1 |
SRP9 | parental protein | 45 | 0.083 | 2308.369 | SRP9-21 (PF05486): Signal recognition particle 9 kDa protein (SRP9) |
2 |
TNKS2 | parental protein | 16 | 0.010 | 992.689 | Ank (PF00023, IPR002110, SM00248): Ankyrin repeat PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies) |
3 |
AAMP | interactor | 5 | 0.700 | 6.000 | PQQ (PF01011, IPR002372, SM00564): PQQ enzyme repeat WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
4 |
AARS | interactor | 8 | 0.357 | 28.015 | DHHA1 (PF02272, IPR003156): DHHA1 domain Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal tRNA-synt_2c (PF01411, IPR018164): tRNA synthetases class II (A) tRNA_SAD (PF07973, IPR012947, SM00863): Threonyl and Alanyl tRNA synthetase second additional domain |
5 |
ABCE1 | interactor | 7 | 0.333 | 85.973 | ABC_tran (PF00005, IPR003439): ABC transporter Fer4 (PF00037, IPR001450): 4Fe-4S binding domain RLI (PF04068, IPR007209): Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain Fer4_7 (PF12838, IPR001450): 4Fe-4S dicluster domain AAA_29 (PF13555): P-loop containing region of AAA domain |
6 |
ACTR2 | interactor | 6 | 0.333 | 8.500 | Actin (PF00022, IPR004000, SM00268): Actin |
7 |
AP2M1 | protein found in more fusions | 3 | 0 | 95.051 | Adap_comp_sub (PF00928, IPR008968): Adaptor complexes medium subunit family Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain |
8 |
AURKA | oncoprotein | 4 | 0.333 | 106.574 | Pkinase (PF00069, IPR000719): Protein kinase domain MTBP_C (PF14920, IPR029418): MDM2-binding |
9 |
BABAM1 | interactor | 2 | 0 | 66.074 | VWA_2 (PF13519, IPR002035): von Willebrand factor type A domain |
10 |
BMI1 | oncoprotein | 8 | 0.524 | 124.580 | zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like |
11 |
CC2D2A | interactor | 1 | 0 | 0 | C2 (PF00168, IPR000008, SM00239): C2 domain ZnuA (PF01297, IPR006127): Zinc-uptake complex component A periplasmic DUF4240 (PF14024, IPR025334): Protein of unknown function (DUF4240) SPT6_acidic (PF14632, IPR028083): Acidic N-terminal SPT6 CC2D2AN-C2 (PF15625, IPR028928): CC2D2A N-terminal C2 domain |
12 |
CEP152 | interactor | 2 | 1.000 | 0 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641) ZapB (PF06005, IPR009252): Cell division protein ZapB DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) Ribosomal_S13 (PF00416, IPR001892): Ribosomal protein S13/S18 FAD-SLDH (PF12318, IPR024651): Membrane bound FAD containing D-sorbitol dehydrogenase YtxH (PF12732, IPR024623): YtxH-like protein ADH_zinc_N_2 (PF13602): Zinc-binding dehydrogenase TolA_bind_tri (PF16331, IPR032519): TolA binding protein trimerisation HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 |
13 |
CEP19 | interactor | 1 | 0 | 0 | CEP19 (PF14933, IPR029412): CEP19-like protein |
14 |
CNTRL | oncoprotein | 2 | 1.000 | 0 | APG6 (PF04111, IPR007243): Autophagy protein Apg6 BcrAD_BadFG (PF01869, IPR002731): BadF/BadG/BcrA/BcrD ATPase family DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724) DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) Fez1 (PF06818): Fez1 Laminin_II (PF06009, IPR010307): Laminin Domain II Ly49 (PF08391, IPR013600): Ly49-like protein, N-terminal region Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal TBPIP (PF07106, IPR010776): Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TMPIT (PF07851, IPR012926): TMPIT-like protein TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5 DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968) LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) LRR_9 (PF14580): Leucine-rich repeat |
15 |
CUL5 | suppressor | 2 | 0 | 100.863 | Cullin (PF00888, IPR001373, SM00182): Cullin family GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
16 |
DCTN1 | protein found in more fusions | 3 | 0 | 105.241 | Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like CAP_GLY (PF01302, IPR000938, SM01052): CAP-Gly domain FlgN (PF05130, IPR007809): FlgN protein HOOK (PF05622, IPR008636): HOOK protein SlyX (PF04102, IPR007236): SlyX TSC22 (PF01166, IPR000580): TSC-22/dip/bun family DUF2443 (PF10398, IPR019469): Protein of unknown function (DUF2443) ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding Dynactin (PF12455, IPR022157): Dynein associated protein Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease KELK (PF15796, IPR031597): KELK-motif containing domain of MRCK Ser/Thr protein kinase |
17 |
DDX20 | interactor | 9 | 0.643 | 9.844 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
18 |
DHPS | protein found in more fusions | 7 | 0.533 | 8.214 | DS (PF01916, IPR002773): Deoxyhypusine synthase |
19 |
DPP8 | interactor | 5 | 0.500 | 3.500 | DPPIV_N (PF00930, IPR002469): Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S15 (PF02129, IPR000383): X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 (PF00326, IPR001375): Prolyl oligopeptidase family |
20 |
EEF2K | interactor | 4 | 0.500 | 2.167 | Alpha_kinase (PF02816, IPR004166, SM00811): Alpha-kinase family Sel1 (PF08238, IPR006597, SM00671): Sel1 repeat |
21 |
EPN3 | interactor | 1 | 0 | 0 | ENTH (PF01417, IPR001026, SM00273): ENTH domain UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif |
22 |
EXOSC1 | interactor | 1 | 0 | 0 | EXOSC1 (PF10447, IPR019495): Exosome component EXOSC1/CSL4 ECR1_N (PF14382, IPR025721): Exosome complex exonuclease RRP4 N-terminal region |
23 |
FTCD | interactor | 2 | 1.000 | 0 | FTCD (PF02971, IPR013802): Formiminotransferase domain FTCD_C (PF04961, IPR007044): Formiminotransferase-cyclodeaminase FTCD_N (PF07837, IPR012886): Formiminotransferase domain, N-terminal subdomain |
24 |
GEMIN2 | interactor | 7 | 0.905 | 1.206 | SIP1 (PF04938): Survival motor neuron (SMN) interacting protein 1 (SIP1) Glyco_trans_4_4 (PF13579, IPR028098): Glycosyl transferase 4-like domain |
25 |
GEMIN4 | interactor | 9 | 0.750 | 6.661 | NA |
26 |
GEMIN5 | interactor | 9 | 0.556 | 168.085 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
27 |
GRB14 | interactor | 2 | 1.000 | 0 | BPS (PF08947, IPR015042): BPS (Between PH and SH2) PH (PF00169, IPR001849, SM00233): PH domain RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain SH2 (PF00017, IPR000980, SM00252): SH2 domain |
28 |
HSF1 | protein found in more fusions | 10 | 0.361 | 155.080 | DUF247 (PF03140, IPR004158): Plant protein of unknown function Vert_HS_TF (PF06546, IPR010542): Vertebrate heat shock transcription factor HSF_DNA-bind (PF00447, IPR000232, SM00415): HSF-type DNA-binding |
29 |
IL7R | interactor | 3 | 0.667 | 1.000 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain |
30 |
IPO11 | interactor | 4 | 0.833 | 0.667 | DUF1539 (PF07560, IPR011436): Domain of Unknown Function (DUF1539) HEAT (PF02985, IPR000357): HEAT repeat IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein HEAT_2 (PF13646): HEAT repeats |
31 |
ITGA4 | interactor | 7 | 0.400 | 158.070 | FG-GAP (PF01839, IPR013517): FG-GAP repeat Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region Integrin_alpha2 (PF08441, IPR013649): Integrin alpha |
32 |
LARS | interactor | 4 | 0.667 | 2.500 | Anticodon_1 (PF08264, IPR013155): Anticodon-binding domain of tRNA tRNA-synt_1 (PF00133, IPR002300): tRNA synthetases class I (I, L, M and V) |
33 |
LNPEP | oncoprotein | 1 | 0 | 0 | Peptidase_M1 (PF01433, IPR014782): Peptidase family M1 ERAP1_C (PF11838, IPR024571): ERAP1-like C-terminal domain Dynactin (PF12455, IPR022157): Dynein associated protein |
34 |
MAPK1 | oncoprotein | 6 | 0 | 369.408 | Pkinase (PF00069, IPR000719): Protein kinase domain |
35 |
METTL18 | interactor | 3 | 1.000 | 0 | Methyltransf_23 (PF13489): Methyltransferase domain |
36 |
MGMT | interactor | 1 | 0 | 0 | DNA_binding_1 (PF01035, IPR014048): 6-O-methylguanine DNA methyltransferase, DNA binding domain Methyltransf_1N (PF02870, IPR008332): 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain |
37 |
MYC | oncoprotein | 8 | 0.286 | 103.684 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region |
38 |
OTUB1 | interactor | 4 | 0.333 | 42.104 | Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain |
39 |
P3H1 | interactor | 7 | 0.429 | 14.339 | TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat YfiO (PF13525): Outer membrane lipoprotein 2OG-FeII_Oxy_3 (PF13640, IPR005123): 2OG-Fe(II) oxygenase superfamily MCM_N (PF14551, IPR027925): MCM N-terminal domain Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat |
40 |
PAXIP1 | interactor | 4 | 0.333 | 124.908 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain IPT (PF01745, IPR002648, SM00429): Isopentenyl transferase SURF6 (PF04935, IPR007019): Surfeit locus protein 6 DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance PTCB-BRCT (PF12738, IPR001357): twin BRCT domain BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT (PF16759, IPR031916): DNA ligase 3 BRCT domain RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain |
41 |
PLIN3 | interactor | 9 | 0.429 | 13.405 | Perilipin (PF03036, IPR004279): Perilipin family |
42 |
POU5F1 | oncoprotein | 8 | 0.333 | 18.289 | Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
43 |
PTEN | suppressor | 3 | 0 | 154.743 | DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein |
44 |
PTGES3 | interactor | 4 | 0.667 | 0.500 | CS (PF04969, IPR007052): CS domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
45 |
RNF166 | interactor | 1 | 0 | 0 | zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding zinc-ribbons_6 (PF07191, IPR010807): zinc-ribbons Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif zinc_ribbon_2 (PF13240, IPR026870): zinc-ribbon domain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain |
46 |
RPRD1A | interactor | 5 | 0.500 | 5.460 | CTD_bind (PF04818, IPR006903): RNA polymerase II-binding domain. GlutR_N (PF05201, IPR015895): Glutamyl-tRNAGlu reductase, N-terminal domain CTK3 (PF12243, IPR024638): CTD kinase subunit gamma CTK3 CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour |
47 |
S100A10 | oncoprotein | 3 | 1.000 | 0 | S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain EF-hand_7 (PF13499, IPR011992): EF-hand domain pair |
48 |
SCLT1 | oncoprotein | 2 | 1.000 | 0 | DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641) DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) SlyX (PF04102, IPR007236): SlyX XhlA (PF10779, IPR019715): Haemolysin XhlA TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding Imm7 (PF15585, IPR028965): Immunity protein 7 CCCAP (PF15964, IPR031887): Centrosomal colon cancer autoantigen protein family DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082) |
49 |
SF1 | protein found in more fusions | 5 | 0.500 | 7.885 | UPF0181 (PF03701, IPR005371): Uncharacterised protein family (UPF0181) zf-CCHC (PF00098, IPR001878): Zinc knuckle KH_1 (PF00013, IPR004088, SM00322): KH domain RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein PRIMA1 (PF16101): Proline-rich membrane anchor 1 SF1-HH (PF16275, IPR032570): Splicing factor 1 helix-hairpin domain |
50 |
SH3BP2 | oncoprotein | 1 | 0 | 0 | PH (PF00169, IPR001849, SM00233): PH domain SH2 (PF00017, IPR000980, SM00252): SH2 domain |
51 |
SLC35A5 | interactor | 1 | 0 | 0 | Nuc_sug_transp (PF04142, IPR007271): Nucleotide-sugar transporter |
52 |
SMN1 | interactor | 9 | 0.750 | 8.106 | SMN (PF06003, IPR010304): Survival motor neuron protein (SMN) |
53 |
SRP14 | interactor | 13 | 0.218 | 69.378 | SRP14 (PF02290, IPR003210): Signal recognition particle 14kD protein |
54 |
SRP54 | interactor | 9 | 0.679 | 8.367 | 5_3_exonuc (PF01367, IPR020045, SM00475): 5'-3' exonuclease, C-terminal SAM fold ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit SRP54 (PF00448, IPR000897, SM00962): SRP54-type protein, GTPase domain SRP54_N (PF02881, IPR013822, SM00963): SRP54-type protein, helical bundle domain SRP_SPB (PF02978, IPR004125): Signal peptide binding domain YlbD_coat (PF14071, IPR025953): Putative coat protein |
55 |
SRP68 | interactor | 5 | 0.700 | 2.167 | RhlB (PF12300, IPR022077): ATP-dependent RNA helicase RhlB SRP68 (PF16969, IPR026258): RNA-binding signal recognition particle 68 |
56 |
SZRD1 | interactor | 3 | 1.000 | 0 | SUZ (PF12752, IPR024771): SUZ domain SUZ-C (PF12901, IPR024642): SUZ-C motif T3SSipB (PF16535, IPR032391): Type III cell invasion protein SipB |
57 |
TERF1 | interactor | 2 | 0 | 0 | TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF) Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain |
58 |
TMEM237 | interactor | 1 | 0 | 0 | TMEM237 (PF15383, IPR029409): Transmembrane protein 237 |
59 |
TNKS1BP1 | interactor | 2 | 0 | 47.741 | Tankyrase_bdg_C (PF15327, IPR032764): Tankyrase binding protein C terminal domain |
60 |
TOMM40 | interactor | 2 | 1.000 | 0 | Porin_3 (PF01459, IPR027246): Eukaryotic porin |
61 |
TXN | oncoprotein | 6 | 0.267 | 80.285 | Thioredoxin (PF00085, IPR013766): Thioredoxin |
62 |
ZNF512B | interactor | 2 | 0 | 48.308 | YTV (PF07639, IPR011521): YTV zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2HC5 (PF06221, IPR009349): Putative zinc finger motif, C2HC5-type zf-Nse (PF11789, IPR004181): Zinc-finger of the MIZ type in Nse subunit Zn_Tnp_IS1595 (PF12760, IPR024442): Transposase zinc-ribbon domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2H2_aberr (PF17017, IPR031514): Aberrant zinc-finger |