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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins DNAJC5 (from a repository: Sun Aug 25 15:19:17 2019)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)8
The number (and %) of the onco-proteins1 (12.50 %)
The number (and %) of the tumor suppressors2 (25.00 %)
Total number of binary PPIs (saturation %)14 (50.00 %)
The number (and %) of affected PPIs7 (50.00 %)
The number of possible different fusions3
PPI diameter2
PPI radius1
The average degree of PPI2.500
Assortativity coefficient-0.5345
The network average Clustering coefficient0.393
The number (and %) of a zero Clustering coefficients4 (50.00 %)
The number (and %) of a zero Betweenness Centrality7 (87.50 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: DNAJC5 All fusions
Proteins found in more fusions STUB1 (see 1 fusions); VCL (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 DNAJC5parental protein70.14336.000DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
Baculo_F (PF12259, IPR022048): Baculovirus F protein
2 ATP6V1B1interactor100ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain
ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain
DUF3533 (PF12051, IPR022703): Protein of unknown function (DUF3533)
3 CFTRsuppressor41.0000ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region
ABC_tran (PF00005, IPR003439): ABC transporter
Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
Rotamase_2 (PF13145, IPR000297): PPIC-type PPIASE domain
CFTR_R (PF14396, IPR025837): Cystic fibrosis TM conductance regulator (CFTR), regulator domain
4 ECE1interactor100Peptidase_M13 (PF01431, IPR018497): Peptidase family M13
Peptidase_M13_N (PF05649, IPR008753): Peptidase family M13
5 HSPA4interactor31.0000Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region
HSP70 (PF00012, IPR013126): Hsp70 protein
TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5
6 PTGFRinteractor2007tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
DUF3784 (PF12650, IPR017259): Domain of unknown function (DUF3784)
7 STUB1suppressor41.0000U-box (PF04564, IPR003613, SM00504): U-box domain
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_20 (PF14561): Tetratricopeptide repeat
8 VCLoncoprotein200Vinculin (PF01044, IPR006077): Vinculin family

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