Find Fusion Network

Fusion ID:
Protein names:

Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins CLASRP, DNAJC5 (from a repository: Thu Feb 8 10:36:27 2018)

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Force Directed
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)26
The number (and %) of the onco-proteins8 (30.77 %)
The number (and %) of the tumor suppressors5 (19.23 %)
Total number of binary PPIs (saturation %)77 (23.69 %)
The number (and %) of affected PPIs24 (31.17 %)
The number of possible different fusions11
PPI diameter5
PPI radius3
The average degree of PPI4.615
Assortativity coefficient-0.1567
The network average Clustering coefficient0.356
The number (and %) of a zero Clustering coefficients6 (23.08 %)
The number (and %) of a zero Betweenness Centrality4 (15.38 %)


List of the fusions

PPI for parental proteins: CLASRP,DNAJC5 All fusions
Proteins found in more fusions LUC7L2 (see 2 fusions); VCL (see 2 fusions); LUC7L (see 1 fusions); CDK6 (see 1 fusions); APP (see 4 fusions); ATXN1 (see 3 fusions); STUB1 (see 1 fusions); DAZAP2 (see 2 fusions); SRPK2 (see 1 fusions); VDR (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Domains (Pfam, InterPro, SMART): description
1 CLASRPparental protein170.169265.826Corona_nucleoca (PF00937, IPR001218): Coronavirus nucleocapsid protein
OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain
Pap_E4 (PF02711, IPR003861): E4 protein
RAP1 (PF07218, IPR009864): Rhoptry-associated protein 1 (RAP-1)
S-antigen (PF05756, IPR008825): S-antigen protein
Transformer (PF06495, IPR010519): Fruit fly transformer protein
DRY_EERY (PF09750, IPR019147, SM01141): Alternative splicing regulator
LRRFIP (PF09738, IPR019139): LRRFIP family
DUF4554 (PF15091, IPR028040): Domain of unknown function (DUF4554)
2 DNAJC5parental protein70.143119.519DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
Baculo_F (PF12259, IPR022048): Baculovirus F protein
3 APPprotein found in more fusions80.28647.867APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
4 ATP6V1B1interactor100ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain
ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain
DUF3533 (PF12051, IPR022703): Protein of unknown function (DUF3533)
5 ATXN1protein found in more fusions70.33346.276AXH (PF08517, IPR013723, SM00536): Ataxin-1 and HBP1 module (AXH)
Spt20 (PF12090, IPR021950): Spt20 family
ATXN-1_C (PF12547, IPR020997): Capicua transcriptional repressor modulator
Cnd1_N (PF12922, IPR024324): non-SMC mitotic condensation complex subunit 1, N-term
6 BARD1suppressor70.46719.979BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
zf-RING_6 (PF14835): zf-RING of BARD1-type protein
BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
7 CDK6suppressor50.5003.936Pkinase (PF00069, IPR000719): Protein kinase domain
8 CFTRsuppressor50.50013.327ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region
ABC_tran (PF00005, IPR003439): ABC transporter
Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
Rotamase_2 (PF13145, IPR000297): PPIC-type PPIASE domain
CFTR_R (PF14396, IPR025837): Cystic fibrosis TM conductance regulator (CFTR), regulator domain
9 CLK1interactor40.33332.383PDGF_N (PF04692, IPR006782): Platelet-derived growth factor, N terminal region
Pkinase (PF00069, IPR000719): Protein kinase domain
10 CLK4interactor100Mu-conotoxin (PF05374, IPR008036): Mu-Conotoxin
Pkinase (PF00069, IPR000719): Protein kinase domain
11 DAB1interactor50.5004.333PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
12 DAZAP2protein found in more fusions50.8330.500DAZAP2 (PF11029, IPR022730): DAZ associated protein 2 (DAZAP2)
13 DYRK1Aoncoprotein50.5003.067DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755)
Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region
Pkinase (PF00069, IPR000719): Protein kinase domain
FAM199X (PF15814, IPR029672): Protein family FAM199X
14 ECE1interactor2012.736Peptidase_M13 (PF01431, IPR018497): Peptidase family M13
Peptidase_M13_N (PF05649, IPR008753): Peptidase family M13
15 HSPA4interactor70.28669.011Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region
HSP70 (PF00012, IPR013126): Hsp70 protein
TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5
16 LUC7Lprotein found in more fusions60.7005.967LUC7 (PF03194, IPR004882): LUC7 N_terminus
Hid1 (PF12722): High-temperature-induced dauer-formation protein
17 LUC7L2protein found in more fusions60.8001.352LUC7 (PF03194, IPR004882): LUC7 N_terminus
Paramyxo_ncap (PF00973, IPR002021): Paramyxovirus nucleocapsid protein
Methyltransf_32 (PF13679, IPR025714): Methyltransferase domain
18 PTGFRinteractor2007tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
DUF3784 (PF12650, IPR017259): Domain of unknown function (DUF3784)
19 RHOXF2interactor50.8330.500DUF367 (PF04034, IPR007177): Domain of unknown function (DUF367)
GRP (PF07172, IPR010800): Glycine rich protein family
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
20 SNIP1interactor30.6671.000FHA (PF00498, IPR000253, SM00240): FHA domain
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
FAM176 (PF14851): FAM176 family
21 SRPK2oncoprotein80.47617.962DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
Pkinase (PF00069, IPR000719): Protein kinase domain
S-antigen (PF05756, IPR008825): S-antigen protein
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
22 STUB1suppressor70.40045.108U-box (PF04564, IPR003613, SM00504): U-box domain
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_20 (PF14561): Tetratricopeptide repeat
23 TERF2interactor40.3339.507Aconitase_C (PF00694, IPR000573): Aconitase C-terminal domain
TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF)
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
TERF2_RBM (PF16772, IPR031902): Telomeric repeat-binding factor 2 Rap1-binding motif
24 VCLoncoprotein309.042Vinculin (PF01044, IPR006077): Vinculin family
25 VDRsuppressor200zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
26 XPO1interactor50.20058.802CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region

B a c k    t o    T o p ⇑