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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)123
The number (and %) of the onco-proteins26 (21.14 %)
The number (and %) of the tumor suppressors9 (7.32 %)
Total number of binary PPIs (saturation %)313 (4.17 %)
The number (and %) of affected PPIs121 (38.66 %)
The number of possible different fusions16
PPI diameter5
PPI radius3
The average degree of PPI4.472
Assortativity coefficient-0.4564
The network average Clustering coefficient0.344
The number (and %) of a zero Clustering coefficients48 (39.02 %)
The number (and %) of a zero Betweenness Centrality56 (45.53 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: MUS81,EFEMP2 All fusions
Proteins found in more fusions CREBBP (see 6 fusions); UBQLN1 (see 2 fusions); NEDD4L (see 4 fusions); SREK1 (see 6 fusions); TRAF6 (see 1 fusions); VCP (see 4 fusions); SFPQ (see 6 fusions); BRAF (see 3 fusions); NPM1 (see 1 fusions); ATN1 (see 1 fusions); ATXN1 (see 3 fusions); HDAC4 (see 1 fusions); TP53 (see 3 fusions); RBPMS (see 1 fusions); SNW1 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 MUS81parental protein710.0278715.040ERCC4 (PF02732, IPR006166, SM00891): ERCC4 domain
MutL (PF13941, IPR006230): MutL protein
HHH_8 (PF14716, IPR010996): Helix-hairpin-helix domain
2 EFEMP2parental protein500.0385313.362EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
hEGF (PF12661, IPR013032): Human growth factor-like EGF
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
Adipogenin (PF15202, IPR027938): Adipogenin
3 ALMS1interactor100PAD_M (PF08527, IPR013733): Protein-arginine deiminase (PAD) middle domain
Preseq_ALAS (PF09029, IPR015118): 5-aminolevulinate synthase presequence
DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306)
DUF4193 (PF13834, IPR025242): Domain of unknown function (DUF4193)
ALMS_motif (PF15309, IPR029299): ALMS motif
4 APEX2interactor21.0000Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family
zf-GRF (PF06839, IPR010666): GRF zinc finger
5 AQP1interactor3028.674MIP (PF00230, IPR000425): Major intrinsic protein
6 ATN1protein found in more fusions100.194451.928Atrophin-1 (PF03154, IPR002951): Atrophin-1 family
7 ATXN1protein found in more fusions100.222541.512AXH (PF08517, IPR013723, SM00536): Ataxin-1 and HBP1 module (AXH)
Spt20 (PF12090, IPR021950): Spt20 family
ATXN-1_C (PF12547, IPR020997): Capicua transcriptional repressor modulator
Cnd1_N (PF12922, IPR024324): non-SMC mitotic condensation complex subunit 1, N-term
8 ATXN7interactor30.333187.451DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
SCA7 (PF08313, IPR013243): SCA7, zinc-binding domain
Macoilin (PF09726, IPR019130): Transmembrane protein
DUF3505 (PF12013, IPR022698): Protein of unknown function (DUF3505)
IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
9 ATXN7L1interactor100SCA7 (PF08313, IPR013243): SCA7, zinc-binding domain
TraV (PF09676, IPR014118): Type IV conjugative transfer system lipoprotein (TraV)
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
DUF3505 (PF12013, IPR022698): Protein of unknown function (DUF3505)
10 BAG6interactor90.179510.280DUF1179 (PF06678, IPR009564): Protein of unknown function (DUF1179)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
DUF2939 (PF11159, IPR021330): Protein of unknown function (DUF2939)
DUF3538 (PF12057, IPR021925): Domain of unknown function (DUF3538)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
11 BLOC1S1interactor100GCN5L1 (PF06320, IPR009395): GCN5-like protein 1 (GCN5L1)
DUF4677 (PF15726, IPR031458): Domain of unknown function (DUF4677)
12 BRAFoncoprotein30212.314Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
RBD (PF02196, IPR003116, SM00455): Raf-like Ras-binding domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
13 BRD9interactor100TFIIF_alpha (PF05793, IPR008851): Transcription initiation factor IIF, alpha subunit (TFIIF-alpha)
NPR3 (PF03666, IPR005365): Nitrogen Permease regulator of amino acid transport activity 3
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
DUF3512 (PF12024, IPR021900): Domain of unknown function (DUF3512)
14 C5orf24interactor100AT_hook (PF02178, IPR017956, SM00384): AT hook motif
15 CACNA1Ainteractor100Ca_chan_IQ (PF08763, IPR014873, SM01062): Voltage gated calcium channel IQ domain
GRP (PF07172, IPR010800): Glycine rich protein family
Ion_trans (PF00520, IPR005821): Ion transport protein
Roughex (PF06020, IPR009259): Drosophila roughex protein
SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region
GPHH (PF16905, IPR031649): Voltage-dependent L-type calcium channel, IQ-associated
16 CATSPER1interactor40.33344.875Ion_trans (PF00520, IPR005821): Ion transport protein
MMM1 (PF10296, IPR019411): Maintenance of mitochondrial morphology protein 1
17 CCDC33interactor90.278134.580C2 (PF00168, IPR000008, SM00239): C2 domain
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
SlyX (PF04102, IPR007236): SlyX
18 CCND3oncoprotein2085.139Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
19 CCNKinteractor41.0000Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387)
20 CCT7interactor40.66729.557Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
21 CDK5RAP2interactor100APG6 (PF04111, IPR007243): Autophagy protein Apg6
bZIP_1 (PF00170, IPR004827): bZIP transcription factor
CALCOCO1 (PF07888, IPR012852): Calcium binding and coiled-coil domain (CALCOCO1) like
DUF16 (PF01519, IPR002862): Protein of unknown function DUF16
DUF1993 (PF09351, IPR018531): Domain of unknown function (DUF1993)
IncA (PF04156, IPR007285): IncA protein
LPP (PF04728, IPR006817): Lipoprotein leucine-zipper
Cnn_1N (PF07989, IPR012943): Centrosomin N-terminal motif 1
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
Tup_N (PF08581, IPR013890): Tup N-terminal
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
Snapin_Pallidin (PF14712, IPR028119): Snapin/Pallidin
GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor
Cyclin_C_2 (PF16899, IPR031658): Cyclin C-terminal domain
22 CHEK2suppressor60.60078.215FHA (PF00498, IPR000253, SM00240): FHA domain
Pkinase (PF00069, IPR000719): Protein kinase domain
23 COL8A1interactor30.6671.000C1q (PF00386, IPR001073, SM00110): C1q domain
Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
24 CREB5interactor50.333114.882bZIP_1 (PF00170, IPR004827): bZIP transcription factor
Zip (PF02535, IPR003689): ZIP Zinc transporter
Shisa (PF13908, IPR026910): Wnt and FGF inhibitory regulator
25 CREBBPsuppressor60.300220.532Creb_binding (PF09030, IPR014744): Creb binding
DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902)
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
KIX (PF02172, IPR003101): KIX domain
MAS20 (PF02064, IPR002056): MAS20 protein import receptor
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger
ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26
HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729)
DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
26 DDX23interactor30.6671.533DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
FUSC (PF04632, IPR006726): Fusaric acid resistance protein family
Transformer (PF06495, IPR010519): Fruit fly transformer protein
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
DUF3698 (PF12479, IPR022167): Protein of unknown function (DUF3698)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
27 DGCR6interactor40.33361.249DGCR6 (PF07324, IPR010849): DiGeorge syndrome critical region 6 (DGCR6) protein
28 DNAJB9interactor31.0000DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
29 DUS3Linteractor100Dus (PF01207, IPR001269): Dihydrouridine synthase (Dus)
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
30 ELK4oncoprotein100Ets (PF00178, IPR000418, SM00413): Ets-domain
31 EME1interactor100.31135.785ERCC4 (PF02732, IPR006166, SM00891): ERCC4 domain
32 EME2interactor100ERCC4 (PF02732, IPR006166, SM00891): ERCC4 domain
HEAT_PBS (PF03130, IPR004155, SM00567): PBS lyase HEAT-like repeat
33 ERCC1oncoprotein50.6003.143Rad10 (PF03834, IPR004579): Binding domain of DNA repair protein Ercc1 (rad10/Swi10)
HHH_5 (PF14520): Helix-hairpin-helix domain
34 FAM107Ainteractor100DUF1151 (PF06625, IPR009533): Protein of unknown function (DUF1151)
35 FAM124Binteractor30.33338.628FAM124 (PF15067, IPR029380): FAM124 family
36 FAM74A4interactor21.0000NA
37 FANCD2oncoprotein30249.317FancD2 (PF14631, IPR029448): Fanconi anaemia protein FancD2 nuclease
38 FBXL5interactor40.6670.952Hemerythrin (PF01814, IPR012312): Hemerythrin HHE cation binding domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
F-box-like (PF12937, IPR001810): F-box-like
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
39 GFI1Boncoprotein100zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
40 GLRX3interactor50.6673.370Glutaredoxin (PF00462, IPR002109): Glutaredoxin
Thioredoxin (PF00085, IPR013766): Thioredoxin
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
41 GTPBP8interactor100GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
MMR_HSR1 (PF01926, IPR006073): 50S ribosome-binding GTPase
42 HDAC4oncoprotein31.0000Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
43 HERC2interactor50.33357.497ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
Cyt-b5 (PF00173, IPR001199, SM01117): Cytochrome b5-like Heme/Steroid binding domain
MIB_HERC2 (PF06701, IPR010606): Mib_herc2
RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat
zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box)
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal
RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
44 HHEXoncoprotein100Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
45 HIST1H2BGoncoprotein50.5005.649Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
46 HNRNPUinteractor110.364139.968CDC45 (PF02724, IPR003874): CDC45-like protein
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SAP (PF02037, IPR003034, SM00513): SAP domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
AAA_33 (PF13671): AAA domain
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
47 HOXA1interactor60.50056.162Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
48 IDH2oncoprotein100Iso_dh (PF00180, IPR024084): Isocitrate/isopropylmalate dehydrogenase
49 IL16oncoprotein200PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
SUZ (PF12752, IPR024771): SUZ domain
50 INO80interactor100Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
RNA_pol_Rbc25 (PF08292, IPR013238): RNA polymerase III subunit Rpc25
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
POTRA (PF07244, IPR010827): Surface antigen variable number repeat
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
DBINO (PF13892, IPR020838): DNA-binding domain
FAM176 (PF14851): FAM176 family
MAP17 (PF15807, IPR031627): Membrane-associated protein 117 kDa, PDZK1-interacting protein 1
51 KIAA2026interactor20137.969IncA (PF04156, IPR007285): IncA protein
FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger
SRP72 (PF08492, IPR013699): SRP72 RNA-binding domain
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
NEXCaM_BD (PF16644, IPR032103): Regulatory region of Na+/H+ exchanger NHE binds to calmodulin
52 KPNA6interactor21.0000Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
IBB (PF01749, IPR002652): Importin beta binding domain
Arm_3 (PF16186, IPR032413): Atypical Arm repeat
53 LCE2Dinteractor41.0000LCE (PF14672, IPR028205): Late cornified envelope
54 LCE3Cinteractor21.0000LCE (PF14672, IPR028205): Late cornified envelope
55 LINGO1interactor100I-set (PF07679, IPR013098): Immunoglobulin I-set domain
LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain
LRR_5 (PF13306, IPR026906): Leucine rich repeats (6 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
56 LTKinteractor100Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Gly_rich (PF12810): Glycine rich protein
FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site
57 MBPinteractor30259.380Myelin_MBP (PF01669, IPR000548): Myelin basic protein
58 MDFIinteractor110.0221539.813MDFI (PF15316, IPR026134): MyoD family inhibitor
59 MEOX2interactor60.267255.888Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
60 NEDD4Lsuppressor40.333173.787WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
61 NOS3interactor200FAD_binding_1 (PF00667, IPR003097): FAD binding domain
Flavodoxin_1 (PF00258, IPR008254): Flavodoxin
NAD_binding_1 (PF00175, IPR001433): Oxidoreductase NAD-binding domain
NO_synthase (PF02898, IPR004030): Nitric oxide synthase, oxygenase domain
HTH_15 (PF12324, IPR024259): Helix-turn-helix domain of alkylmercury lyase
62 NPM1suppressor80.61964.740Nucleoplasmin (PF03066): Nucleoplasmin/nucleophosmin domain
SDA1 (PF05285, IPR007949): SDA1
NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain
63 NUFIP2interactor20138.014PAT1 (PF09770, IPR019167): Topoisomerase II-associated protein PAT1
NUFIP2 (PF15293, IPR032747): Nuclear fragile X mental retardation-interacting protein 2
64 PCNX2interactor100Pecanex_C (PF05041, IPR007735): Pecanex protein (C-terminus)
DUF4131 (PF13567, IPR025405): Domain of unknown function (DUF4131)
65 PIDD1interactor2028.674Death (PF00531, IPR000488, SM00005): Death domain
ZU5 (PF00791, IPR000906, SM00218): ZU5 domain
Peptidase_S68 (PF10461, IPR019502): Peptidase S68
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
66 PIGBinteractor100Glyco_transf_22 (PF03901, IPR005599): Alg9-like mannosyltransferase family
67 PLEK2oncoprotein100DEP (PF00610, IPR000591, SM00049): Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)
PH (PF00169, IPR001849, SM00233): PH domain
68 PLK1suppressor110.291372.593Pkinase (PF00069, IPR000719): Protein kinase domain
POLO_box (PF00659, IPR000959): POLO box duplicated region
69 PLSCR1interactor120.227104.231Scramblase (PF03803, IPR005552): Scramblase
70 PLSCR4interactor21.0000Scramblase (PF03803, IPR005552): Scramblase
71 POLD2interactor100DNA_pol_E_B (PF04042, IPR007185): DNA polymerase alpha/epsilon subunit B
72 POLR2Linteractor21.0000RNA_pol_N (PF01194, IPR000268): RNA polymerases N / 8 kDa subunit
73 POLR3Kinteractor100RNA_POL_M_15KD (PF02150, IPR001529): RNA polymerases M/15 Kd subunit
TFIIS_C (PF01096, IPR001222): Transcription factor S-II (TFIIS)
zf-ribbon_3 (PF13248): zinc-ribbon domain
zf-SAP30 (PF13866, IPR025717): SAP30 zinc-finger
74 PTGER3interactor40.33364.3697tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
FtsX (PF02687, IPR003838): FtsX-like permease family
75 RAMP1oncoprotein200RAMP (PF04901, IPR006985): Receptor activity modifying family
76 RBPMSprotein found in more fusions90.39321.635RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
77 REREoncoprotein31.0000Atrophin-1 (PF03154, IPR002951): Atrophin-1 family
BAH (PF01426, IPR001025, SM00439): BAH domain
ELM2 (PF01448, IPR000949): ELM2 domain
POPLD (PF08170, IPR012590): POPLD (NUC188) domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
GATA (PF00320, IPR000679, SM00401): GATA zinc finger
78 RFC1interactor40.50042.696AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
GAGA_bind (PF06217, IPR010409): GAGA binding protein-like family
Nexin_C (PF08628, IPR013937): Sorting nexin C terminal
RFC1 (PF08519, IPR013725): Replication factor RFC1 C terminal domain
DUF2316 (PF10078, IPR018757): Uncharacterized protein conserved in bacteria (DUF2316)
79 RFTN1interactor100Raftlin (PF15250, IPR028169): Raftlin
80 RHOXF2interactor70.6006.808DUF367 (PF04034, IPR007177): Domain of unknown function (DUF367)
GRP (PF07172, IPR010800): Glycine rich protein family
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
81 RHPN1interactor100BRO1 (PF03097, IPR004328, SM01041): BRO1-like domain
HR1 (PF02185, IPR011072, SM00742): Hr1 repeat
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
82 RIBC2interactor100RIB43A (PF05914, IPR008805): RIB43A
83 RPL10suppressor70.429189.068Ribosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e
84 RPS3interactor60.73333.309KH_2 (PF07650, IPR004044): KH domain
Ribosomal_S3_C (PF00189, IPR001351): Ribosomal protein S3, C-terminal domain
85 SAMD4Binteractor100PHAT (PF09246, IPR015327): PHAT
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
86 SF3A2interactor30.6670.667Cytadhesin_P30 (PF07271, IPR009896): Cytadhesin P30/P32
PRP4 (PF08799, IPR014906): pre-mRNA processing factor 4 (PRP4) like
Totivirus_coat (PF05518, IPR008871): Totivirus coat protein
zf-met (PF12874): Zinc-finger of C2H2 type
ARL6IP6 (PF15062, IPR029383): Haemopoietic lineage transmembrane helix
SF3A2 (PF16835, IPR031781): Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11)
87 SFPQoncoprotein40.6671.515GRP (PF07172, IPR010800): Glycine rich protein family
Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
NOPS (PF08075, IPR012975): NOPS (NUC059) domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
PAT1 (PF09770, IPR019167): Topoisomerase II-associated protein PAT1
CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
88 SGTAinteractor21.0000TOM20_plant (PF06552, IPR010547): Plant specific mitochondrial import receptor subunit TOM20
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
XPC-binding (PF09280, IPR015360): XPC-binding domain
TPR_17 (PF13431): Tetratricopeptide repeat
SGTA_dimer (PF16546, IPR032374): Homodimerisation domain of SGTA
89 SGTBinteractor21.0000TOM20_plant (PF06552, IPR010547): Plant specific mitochondrial import receptor subunit TOM20
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
XPC-binding (PF09280, IPR015360): XPC-binding domain
TPR_11 (PF13414, IPR011990): TPR repeat
SGTA_dimer (PF16546, IPR032374): Homodimerisation domain of SGTA
90 SLX1Ainteractor40.8330.400GIY-YIG (PF01541, IPR000305, SM00465): GIY-YIG catalytic domain
FANCL_C (PF11793, IPR026850): FANCL C-terminal domain
91 SLX1Binteractor50.7003.530GIY-YIG (PF01541, IPR000305, SM00465): GIY-YIG catalytic domain
FANCL_C (PF11793, IPR026850): FANCL C-terminal domain
92 SLX4suppressor90.47247.915BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Slx4 (PF09494, IPR018574): Slx4 endonuclease
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
93 SNW1protein found in more fusions90.286301.114SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
SIR4_SID (PF16991, IPR031556): Sir4 SID domain
94 SORT1interactor30.6671.000Sortilin_C (PF15901, IPR031777): Sortilin, neurotensin receptor 3, C-terminal
Sortilin-Vps10 (PF15902, IPR031778): Sortilin, neurotensin receptor 3,
95 SREK1protein found in more fusions50.6671.667Ureide_permease (PF07168, IPR009834): Ureide permease
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RP-C_C (PF11800, IPR021760): Replication protein C C-terminal region
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
BRD4_CDT (PF17105, IPR031354): C-terminal domain of bromodomain protein 4
96 STILoncoprotein100STIL_N (PF15253, IPR026123): SCL-interrupting locus protein N-terminus
97 STK16interactor50.6673.209Pkinase (PF00069, IPR000719): Protein kinase domain
98 SUMO2interactor80.429150.630Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like
99 TCAF1interactor21.0000Peptidase_M60 (PF13402, IPR031161): Peptidase M60, enhancin and enhancin-like
100 TERF2interactor70.400186.334Aconitase_C (PF00694, IPR000573): Aconitase C-terminal domain
TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF)
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
TERF2_RBM (PF16772, IPR031902): Telomeric repeat-binding factor 2 Rap1-binding motif
101 TERToncoprotein2027.655RVT_1 (PF00078, IPR000477): Reverse transcriptase (RNA-dependent DNA polymerase)
Telomerase_RBD (PF12009, IPR021891, SM00975): Telomerase ribonucleoprotein complex - RNA binding domain
102 TFB1Minteractor21.0000RrnaAD (PF00398, IPR001737, SM00650): Ribosomal RNA adenine dimethylase
103 TIMELESSinteractor100Myc_N (PF01056, IPR012682): Myc amino-terminal region
TIMELESS (PF04821, IPR006906): Timeless protein
TIMELESS_C (PF05029, IPR007725): Timeless protein C terminal region
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
104 TMEM209interactor100CytochromB561_N (PF09786, IPR019176): Cytochrome B561, N terminal
105 TP53suppressor170.1331718.186DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
106 TRAF6protein found in more fusions50.333301.536SlyX (PF04102, IPR007236): SlyX
zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
107 TRIM24suppressor3027.655PHD (PF00628, IPR019787, SM00249): PHD-finger
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
Siva (PF05458, IPR022773): Cd27 binding protein (Siva)
zf-MYND (PF01753, IPR002893): MYND finger
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
Imm68 (PF15583, IPR028276): Immunity protein 68
SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1
108 UBQLN1protein found in more fusions40.33359.418Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
XPC-binding (PF09280, IPR015360): XPC-binding domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
Fur_reg_FbpB (PF13040, IPR025004): Fur-regulated basic protein B
FAM199X (PF15814, IPR029672): Protein family FAM199X
109 UBQLN4interactor70.33318.233CRF (PF00473, IPR000187, SM00039): Corticotropin-releasing factor family
DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
Arm_2 (PF04826, IPR006911): Armadillo-like
NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
XPC-binding (PF09280, IPR015360): XPC-binding domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
Fur_reg_FbpB (PF13040, IPR025004): Fur-regulated basic protein B
partial_CstF (PF15861, IPR031721): Partial cleavage stimulation factor domain
110 UHRF1interactor80.429106.390PHD (PF00628, IPR019787, SM00249): PHD-finger
SAD_SRA (PF02182, IPR003105, SM00466): SAD/SRA domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
TTD (PF12148, IPR021991): Tandem tudor domain within UHRF1
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
zf-RING_10 (PF16685, IPR032043): zinc RING finger of MSL2
111 VCPprotein found in more fusions190.176988.696AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2
CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain
TniB (PF05621, IPR008868): Bacterial TniB protein
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
112 VWCEinteractor100EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
RecO_C (PF02565, IPR003717): Recombination protein O C terminal
VWC (PF00093, IPR001007, SM00214): von Willebrand factor type C domain
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
113 WEE1interactor21.0000Pkinase (PF00069, IPR000719): Protein kinase domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
114 WRNoncoprotein70.53336.985DNA_pol_A_exo1 (PF01612, IPR002562, SM00474): 3'-5' exonuclease
DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
HRDC (PF00570, IPR002121, SM00341): HRDC domain
Laminin_II (PF06009, IPR010307): Laminin Domain II
RQC (PF09382, IPR018982, SM00956): RQC domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
HTH_40 (PF14493, IPR029491): Helix-turn-helix domain
RecQ_Zn_bind (PF16124, IPR032284): RecQ zinc-binding
115 XIAPinteractor40.6674.330BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
116 ZNF142interactor100DUF1610 (PF07754, IPR011668): Domain of unknown function (DUF1610)
FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zinc_ribbon_12 (PF11331, IPR021480): Probable zinc-ribbon domain
DUF3505 (PF12013, IPR022698): Protein of unknown function (DUF3505)
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zinc_ribbon_4 (PF13717): zinc-ribbon domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain
zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
CpXC (PF14353, IPR025682): CpXC protein
zf-tcix (PF14952, IPR029269): Putative treble-clef, zinc-finger, Zn-binding
FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain
117 ZNF17interactor100KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-LYAR (PF08790, IPR014898): LYAR-type C2HC zinc finger
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2HE (PF16278, IPR032566): C2HE / C2H2 / C2HC zinc-binding finger
118 ZNF181interactor100KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
119 ZNF263interactor21.0000KRAB (PF01352, IPR001909, SM00349): KRAB box
SCAN (PF02023, IPR003309, SM00431): SCAN domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zinc_ribbon_2 (PF13240, IPR026870): zinc-ribbon domain
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
120 ZNF358interactor100Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
121 ZNF426interactor30.333105.400KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
122 ZNF496interactor21.0000zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding
KRAB (PF01352, IPR001909, SM00349): KRAB box
SCAN (PF02023, IPR003309, SM00431): SCAN domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
123 ZNF638interactor30.333135.966RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
zf-met (PF12874): Zinc-finger of C2H2 type
Ferlin_C (PF16165, IPR032362): Ferlin C-terminus

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