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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins FAM19A1, ABHD16A (from a repository: Fri Jul 26 07:03:11 2019)

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)22
The number (and %) of the onco-proteins2 (9.09 %)
The number (and %) of the tumor suppressors2 (9.09 %)
Total number of binary PPIs (saturation %)28 (12.12 %)
The number (and %) of affected PPIs20 (71.43 %)
The number of possible different fusions1
PPI diameter2
PPI radiusinf
The average degree of PPI2.182
Assortativity coefficient-0.3507
The network average Clustering coefficient0.190
The number (and %) of a zero Clustering coefficients16 (72.73 %)
The number (and %) of a zero Betweenness Centrality19 (86.36 %)


List of the fusions

Proteins found in more fusions

List of active interactors

# Name Type Number of PPI (degree) Clustering
Domains (Pfam, InterPro, SMART): description
1 FAM19A1parental protein100TAFA (PF12020, IPR020350): TAFA family
2 ABHD16Aparental protein190.023330.000Abhydrolase_1 (PF00561, IPR000073): alpha/beta hydrolase fold
Abhydrolase_6 (PF12697, IPR000073): Alpha/beta hydrolase family
3 ATP5G3interactor21.0000ATP-synt_C (PF00137, IPR002379): ATP synthase subunit C
TM1506 (PF08973, IPR015067): Domain of unknown function (DUF1893)
4 CREB3interactor31.0000bZIP_1 (PF00170, IPR004827): bZIP transcription factor
GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor
5 DNAJC1interactor100DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
DUF4234 (PF14018, IPR025328): Domain of unknown function (DUF4234)
6 DTX2oncoprotein200WWE (PF02825, IPR004170, SM00678): WWE domain
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
zf-UDP (PF14569, IPR027934): Zinc-binding RING-finger
7 FAM134Cinteractor21.0000Reticulon (PF02453, IPR003388): Reticulon
8 GPRC5Cinteractor1007tm_3 (PF00003, IPR017978): 7 transmembrane sweet-taste receptor of 3 GCPR
DUF1467 (PF07330, IPR009935): Protein of unknown function (DUF1467)
9 HM13interactor100Peptidase_A22B (PF04258, IPR007369): Signal peptide peptidase
DUF4345 (PF14248, IPR025597): Domain of unknown function (DUF4345)
10 HTR3Cinteractor100Neur_chan_LBD (PF02931, IPR006202): Neurotransmitter-gated ion-channel ligand binding domain
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
11 IFITM1interactor100CD225 (PF04505, IPR007593): Interferon-induced transmembrane protein
12 MCOLN3interactor100PKD_channel (PF08016, IPR013122): Polycystin cation channel
13 MLH1suppressor100DNA_mis_repair (PF01119, IPR013507): DNA mismatch repair protein, C-terminal domain
HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
Mlh1_C (PF16413, IPR032189): DNA mismatch repair protein Mlh1 C-terminus
14 NXF1interactor50.5003.000NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding
TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
15 RABGGTBoncoprotein100Prenyltrans (PF00432, IPR001330): Prenyltransferase and squalene oxidase repeat
16 RICTORinteractor100RasGEF_N_2 (PF14663, IPR029453): Rapamycin-insensitive companion of mTOR RasGEF_N domain
RICTOR_N (PF14664, IPR028267): Rapamycin-insensitive companion of mTOR, N-term
RICTOR_phospho (PF14665, IPR029259): Rapamycin-insensitive companion of mTOR, phosphorylation-site
RICTOR_M (PF14666, IPR029451): Rapamycin-insensitive companion of mTOR, middle domain
RICTOR_V (PF14668, IPR029452): Rapamycin-insensitive companion of mTOR, domain 5
17 RNF5interactor200zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
18 SAFBsuppressor100RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SAP (PF02037, IPR003034, SM00513): SAP domain
Ferlin_C (PF16165, IPR032362): Ferlin C-terminus
19 SPAG7interactor100DUF1451 (PF07295, IPR009912): Zinc-ribbon containing domain
R3H (PF01424, IPR001374, SM00393): R3H domain
20 TMEM147interactor100DUF2053 (PF09767, IPR019164): Predicted membrane protein (DUF2053)
21 TMEM222interactor30.6671.000DUF778 (PF05608, IPR008496): Protein of unknown function (DUF778)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
22 UPF1interactor100UPF1_Zn_bind (PF09416, IPR018999): RNA helicase (UPF2 interacting domain)
AAA_11 (PF13086): AAA domain
AAA_12 (PF13087): AAA domain

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