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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins DDX39B, HIVEP1 (from a repository: Sun Sep 23 03:57:30 2018)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)126
The number (and %) of the onco-proteins40 (31.75 %)
The number (and %) of the tumor suppressors14 (11.11 %)
Total number of binary PPIs (saturation %)785 (9.97 %)
The number (and %) of affected PPIs125 (15.92 %)
The number of possible different fusions25
PPI diameter4
PPI radius2
The average degree of PPI11.587
Assortativity coefficient-0.1831
The network average Clustering coefficient0.395
The number (and %) of a zero Clustering coefficients16 (12.70 %)
The number (and %) of a zero Betweenness Centrality13 (10.32 %)

ACTIVE INTERACTORS


List of the fusions

Proteins found in more fusions SREK1 (see 4 fusions); SMAD4 (see 2 fusions); MAGED1 (see 1 fusions); STAU1 (see 2 fusions); YWHAG (see 1 fusions); U2AF2 (see 2 fusions); CUL7 (see 2 fusions); PABPC1 (see 2 fusions); ATXN1 (see 3 fusions); SRPK2 (see 1 fusions); MAPK14 (see 1 fusions); PRKAR1A (see 2 fusions); STAT3 (see 2 fusions); EIF4A2 (see 2 fusions); IMMT (see 4 fusions); FANCA (see 1 fusions); THOC1 (see 3 fusions); HDAC5 (see 1 fusions); FN1/YWHAG (see 1 fusions); UBC (see 1 fusions); APH1A (see 2 fusions); SMAD3 (see 3 fusions); SUZ12 (see 2 fusions); SNW1 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 DDX39Bparental protein790.1393921.154DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
2 HIVEP1parental protein460.0343902.521PHD (PF00628, IPR019787, SM00249): PHD-finger
PyrI_C (PF02748, IPR020542): Aspartate carbamoyltransferase regulatory chain, metal binding domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain
zf-C2H2_7 (PF15269): Zinc-finger
3 ACADMoncoprotein90.6119.607Acyl-CoA_dh_1 (PF00441, IPR009075): Acyl-CoA dehydrogenase, C-terminal domain
Acyl-CoA_dh_M (PF02770, IPR006091): Acyl-CoA dehydrogenase, middle domain
Acyl-CoA_dh_N (PF02771, IPR013786): Acyl-CoA dehydrogenase, N-terminal domain
4 AHSA1interactor120.33358.910Aha1_N (PF09229, IPR015310, SM01000): Activator of Hsp90 ATPase, N-terminal
AHSA1 (PF08327, IPR013538): Activator of Hsp90 ATPase homolog 1-like protein
5 ALDOBoncoprotein100Glycolytic (PF00274, IPR000741): Fructose-bisphosphate aldolase class-I
6 ALYREFinteractor330.351245.387FYTT (PF07078, IPR009782): Forty-two-three protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
7 APH1Aoncoprotein40.6676.866Aph-1 (PF06105, IPR009294): Aph-1 protein
8 APTXinteractor2030.169FHA (PF00498, IPR000253, SM00240): FHA domain
DcpS_C (PF11969): Scavenger mRNA decapping enzyme C-term binding
zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
zf-C2HE (PF16278, IPR032566): C2HE / C2H2 / C2HC zinc-binding finger
9 ASGR1interactor100Lectin_N (PF03954, IPR005640): Hepatic lectin, N-terminal domain
Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain
10 ATF2oncoprotein130.212104.145bZIP_1 (PF00170, IPR004827): bZIP transcription factor
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
11 ATXN1protein found in more fusions60.40013.867AXH (PF08517, IPR013723, SM00536): Ataxin-1 and HBP1 module (AXH)
Spt20 (PF12090, IPR021950): Spt20 family
ATXN-1_C (PF12547, IPR020997): Capicua transcriptional repressor modulator
Cnd1_N (PF12922, IPR024324): non-SMC mitotic condensation complex subunit 1, N-term
12 ATXN1Linteractor40.33315.439AXH (PF08517, IPR013723, SM00536): Ataxin-1 and HBP1 module (AXH)
13 BACH1interactor60.5007.557BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor
Cep57_CLD_2 (PF14197, IPR025925): Centrosome localisation domain of PPC89
14 BARD1suppressor160.190164.712BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
zf-RING_6 (PF14835): zf-RING of BARD1-type protein
BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
15 BCLAF1oncoprotein220.355170.131API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5)
GRP (PF07172, IPR010800): Glycine rich protein family
Apis_Csd (PF11671, IPR021007): Complementary sex determiner protein
FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal
THRAP3_BCLAF1 (PF15440, IPR029199): THRAP3/BCLAF1 family
16 BHLHE40interactor80.52415.986Hairy_orange (PF07527, IPR003650): Hairy Orange
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
17 BMI1oncoprotein180.287109.995zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
18 BNIP3oncoprotein3032.392BNIP3 (PF06553, IPR010548): BNIP3
19 BRCA1suppressor220.138507.405BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT
20 BTRConcoprotein180.199230.890WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
21 C12orf10interactor40.8330.275UPF0160 (PF03690, IPR003226): Uncharacterised protein family (UPF0160)
22 CACNA1Ainteractor2015.667Ca_chan_IQ (PF08763, IPR014873, SM01062): Voltage gated calcium channel IQ domain
GRP (PF07172, IPR010800): Glycine rich protein family
Ion_trans (PF00520, IPR005821): Ion transport protein
Roughex (PF06020, IPR009259): Drosophila roughex protein
SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region
GPHH (PF16905, IPR031649): Voltage-dependent L-type calcium channel, IQ-associated
23 CDC5Linteractor250.330147.989OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component
Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
24 CDK2suppressor150.28689.580Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
25 CDKN2AIPinteractor60.40054.333XTBD (PF11952, IPR021859): XRN-Two Binding Domain, XTBD
26 CHST15interactor100Sulfotransfer_3 (PF13469): Sulfotransferase family
27 CLK1interactor60.40076.159PDGF_N (PF04692, IPR006782): Platelet-derived growth factor, N terminal region
Pkinase (PF00069, IPR000719): Protein kinase domain
28 CUL7protein found in more fusions270.298204.206ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
Cullin (PF00888, IPR001373, SM00182): Cullin family
DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918)
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
29 DDOSTinteractor160.40043.523DDOST_48kD (PF03345, IPR005013): Oligosaccharyltransferase 48 kDa subunit beta
30 DDX39Ainteractor240.273192.488DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
31 DHX38interactor40.6672.255DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold
DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2)
Nucleo_P87 (PF07267, IPR009893): Nucleopolyhedrovirus capsid protein P87
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
DUF2956 (PF11169, IPR021339): Protein of unknown function (DUF2956)
32 DNAJA1interactor120.318139.945DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
33 DNM2interactor80.5005.058Dynamin_M (PF01031, IPR000375): Dynamin central region
GED (PF02212, IPR003130, SM00302): Dynamin GTPase effector domain
PH (PF00169, IPR001849, SM00233): PH domain
Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family
34 EEDsuppressor230.342117.113WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
35 EIF4A2oncoprotein50.5001.291DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
36 ELAVL1oncoprotein410.2031122.701RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
37 EMDinteractor150.35244.579LEM (PF03020, IPR003887, SM00540): LEM domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
38 ETFAinteractor80.50011.815ETF (PF01012, IPR014730, SM00893): Electron transfer flavoprotein domain
ETF_alpha (PF00766, IPR014731): Electron transfer flavoprotein FAD-binding domain
39 FANCAoncoprotein300.811Fanconi_A (PF03511, IPR003516): Fanconi anaemia group A protein
Fanconi_A_N (PF15865, IPR031729): Fanconi anaemia group A protein N terminus
40 FBXW11interactor120.327130.959WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
41 FN1oncoprotein180.31468.987fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
42 FYTTD1interactor110.62214.252FYTT (PF07078, IPR009782): Forty-two-three protein
43 GAAinteractor2010.844Glyco_hydro_31 (PF01055, IPR000322): Glycosyl hydrolases family 31
Trefoil (PF00088, IPR000519, SM00018): Trefoil (P-type) domain
Gal_mutarotas_2 (PF13802, IPR025887): Galactose mutarotase-like
NtCtMGAM_N (PF16863, IPR031727): N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase
DUF5110 (PF17137): Domain of unknown function (DUF5110)
44 GSDMBinteractor21.0000Gasdermin (PF04598, IPR007677): Gasdermin family
45 GSRinteractor80.57111.568Pyr_redox_2 (PF07992, IPR023753): Pyridine nucleotide-disulphide oxidoreductase
Pyr_redox_dim (PF02852, IPR004099): Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
46 HDAC5protein found in more fusions170.32562.559Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NOA36 (PF06524, IPR010531): NOA36 protein
Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
47 HPDinteractor21.0000Glyoxalase (PF00903, IPR004360): Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
Glyoxalase_3 (PF13468, IPR025870): Glyoxalase-like domain
48 HSPA1Ainteractor170.221253.498HSP70 (PF00012, IPR013126): Hsp70 protein
49 HSPD1suppressor240.257210.753Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
50 IL7Rinteractor70.8570.507fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
51 IMMTprotein found in more fusions110.067100.961Mitofilin (PF09731, IPR019133): Mitochondrial inner membrane protein
52 IRF5suppressor200IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor
IRF-3 (PF10401, IPR019471): Interferon-regulatory factor 3
53 ITGA4interactor160.40056.055FG-GAP (PF01839, IPR013517): FG-GAP repeat
Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region
Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
54 KBTBD7interactor40.16736.224BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_2 (PF07646, IPR011498): Kelch motif
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_4 (PF13418): Galactose oxidase, central domain
Kelch_6 (PF13964): Kelch motif
55 LSM4interactor21.0000LSM (PF01423, IPR001163): LSM domain
56 LUZP4interactor110.51115.037Pox_Ag35 (PF03286, IPR004966): Pox virus Ag35 surface protein
ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26
DUF2570 (PF10828, IPR022538): Protein of unknown function (DUF2570)
57 MAGED1protein found in more fusions60.30032.121MAGE (PF01454, IPR002190): MAGE family
58 MAGOHBinteractor70.38110.812Mago_nashi (PF02792, IPR004023): Mago nashi protein
59 MAPK14oncoprotein80.28649.923Pkinase (PF00069, IPR000719): Protein kinase domain
60 MAPK8oncoprotein60.30035.976DUF530 (PF04409, IPR007503): Protein of unknown function (DUF530)
Pkinase (PF00069, IPR000719): Protein kinase domain
61 MOB4interactor40.5002.500Mob1_phocein (PF03637, IPR005301): Mob1/phocein family
62 MTMR3oncoprotein2017.248FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
Myotub-related (PF06602, IPR010569): Myotubularin-like phosphatase domain
FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger
63 MYO1Cinteractor60.6003.738IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_TH1 (PF06017, IPR010926): Unconventional myosin tail, actin- and lipid-binding
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
64 NCBP1interactor210.400204.011MIF4G (PF02854, IPR003890, SM00543): MIF4G domain
MIF4G_like (PF09088, IPR015172): MIF4G like
MIF4G_like_2 (PF09090, IPR015174): MIF4G like
SlyX (PF04102, IPR007236): SlyX
65 NCBP2interactor40.6671.591RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
66 NCBP3interactor170.50063.922Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM)
TLP-20 (PF06088, IPR009092): Nucleopolyhedrovirus telokin-like protein-20 (TLP20)
TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit
NCBP3 (PF10309, IPR019416): Nuclear cap-binding protein subunit 3
RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31
CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal
67 NDRG1suppressor60.4673.788Ndr (PF03096, IPR004142): Ndr family
68 NHLH1interactor206.866HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
69 NINJ1suppressor100Ninjurin (PF04923, IPR007007): Ninjurin
70 NR5A1interactor50.7002.067zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
PRIMA1 (PF16101): Proline-rich membrane anchor 1
71 NTRK1oncoprotein470.1591328.370I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
72 NUCB1interactor100DUF1104 (PF06518, IPR009488): Protein of unknown function (DUF1104)
Spc24 (PF08286, IPR013252): Spc24 subunit of Ndc80
DUF2967 (PF11179, IPR021349): Protein of unknown function (DUF2967)
DUF3552 (PF12072, IPR022711): Domain of unknown function (DUF3552)
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
73 OBSL1interactor240.316183.832BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
74 PABPC1oncoprotein270.274219.646RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain
YflT (PF11181, IPR025889): Heat induced stress protein YflT
75 PABPC4interactor220.346132.430ApbA_C (PF08546, IPR013752): Ketopantoate reductase PanE/ApbA C terminal
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain
HHV-5_US34A (PF17087, IPR031384): Herpesvirus US34A protein family
76 PRKAR1Asuppressor70.40030.292RIIa (PF02197, IPR003117, SM00394): Regulatory subunit of type II PKA R-subunit
cNMP_binding (PF00027, IPR000595, SM00100): Cyclic nucleotide-binding domain
77 PYM1interactor40.6671.400CcmD (PF04995, IPR007078): Heme exporter protein D (CcmD)
Mago-bind (PF09282, IPR015362): Mago binding
AAA_23 (PF13476): AAA domain
78 RAB1Aoncoprotein100.311176.793Ras (PF00071, IPR001806, SM00173): Ras family
79 RAB5Aoncoprotein70.47653.342Ras (PF00071, IPR001806, SM00173): Ras family
80 RAE1interactor110.47343.036Exonuc_X-T_C (PF08411, IPR013620): Exonuclease C-terminal
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
81 RBBP4oncoprotein140.45124.395eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein
CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
82 RBM8Ainteractor160.248193.371RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
83 RIDAinteractor40.6671.000Ribonuc_L-PSP (PF01042, IPR006175): Endoribonuclease L-PSP
84 RNASEH2Ainteractor40.16733.343RNase_HII (PF01351, IPR024567): Ribonuclease HII
85 RNASEH2Binteractor3043.716RNase_H2-Ydr279 (PF09468, IPR019024): Ydr279p protein family (RNase H2 complex component)
86 RNF2interactor270.354157.107zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
87 RPN1oncoprotein220.342152.284Ribophorin_I (PF04597, IPR007676): Ribophorin I
CtIP_N (PF10482, IPR019518): Tumour-suppressor protein CtIP N-terminal domain
88 RPN2interactor100.55622.915Ribophorin_II (PF05817, IPR008814): Oligosaccharyltransferase subunit Ribophorin II
89 RPS7interactor110.27336.537Ribosomal_S7e (PF01251, IPR000554): Ribosomal protein S7e
90 SDCBPinteractor60.46729.578PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
91 SERTAD1interactor30.6671.783CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
SERTA (PF06031, IPR009263): SERTA motif
92 SHFM1interactor50.7002.354CLLAC (PF15675, IPR031379): CLLAC-motif containing domain
93 SMAD3oncoprotein140.205239.218MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
94 SMAD4suppressor110.42241.391MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
95 SNW1protein found in more fusions250.297213.717SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
SIR4_SID (PF16991, IPR031556): Sir4 SID domain
96 SNX4interactor100PX (PF00787, IPR001683, SM00312): PX domain
Vps5 (PF09325, IPR015404): Vps5 C terminal like
97 SOCS3suppressor206.866SH2 (PF00017, IPR000980, SM00252): SH2 domain
SOCS_box (PF07525, IPR001496): SOCS box
98 SOD1interactor60.50033.317Sod_Cu (PF00080, IPR001424): Copper/zinc superoxide dismutase (SODC)
99 SREK1protein found in more fusions80.7621.119Ureide_permease (PF07168, IPR009834): Ureide permease
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RP-C_C (PF11800, IPR021760): Replication protein C C-terminal region
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
BRD4_CDT (PF17105, IPR031354): C-terminal domain of bromodomain protein 4
100 SRPK2oncoprotein170.325422.366DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
Pkinase (PF00069, IPR000719): Protein kinase domain
S-antigen (PF05756, IPR008825): S-antigen protein
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
101 SSR3interactor50.9000.628TRAP-gamma (PF07074, IPR009779): Translocon-associated protein, gamma subunit (TRAP-gamma)
102 STAT3suppressor70.40041.801SH2 (PF00017, IPR000980, SM00252): SH2 domain
STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain
STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain
STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
103 STAT5Boncoprotein60.30051.156SH2 (PF00017, IPR000980, SM00252): SH2 domain
STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain
STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain
STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
104 STAU1protein found in more fusions170.43339.377dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
Staufen_C (PF16482, IPR032478): Staufen C-terminal domain
105 STRN4interactor40.6675.011CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
Striatin (PF08232, IPR013258): Striatin family
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
106 SUZ12suppressor270.265263.345DUF2070 (PF09843, IPR019204): Predicted membrane protein (DUF2070)
VEFS-Box (PF09733, IPR019135): VEFS-Box of polycomb protein
107 TECRinteractor90.61112.856Steroid_dh (PF02544, IPR001104): 3-oxo-5-alpha-steroid 4-dehydrogenase
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
108 TFAP4oncoprotein50.4009.318DivIC (PF04977, IPR007060): Septum formation initiator
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
DUF2407 (PF10302, IPR019413): DUF2407 ubiquitin-like domain
109 THOC1protein found in more fusions160.68611.741Death (PF00531, IPR000488, SM00005): Death domain
efThoc1 (PF11957, IPR021861): THO complex subunit 1 transcription elongation factor
110 THOC2interactor260.332407.033Sec62 (PF03839, IPR004728): Translocation protein Sec62
Tho2 (PF11262, IPR021418): Transcription factor/nuclear export subunit protein 2
Thoc2 (PF11732, IPR021726): Transcription- and export-related complex subunit
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
THOC2_N (PF16134, IPR032302): THO complex subunit 2 N-terminus
111 THOC3interactor100.75613.586eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
112 THOC5oncoprotein170.53741.313FimP (PF09766, IPR019163): Fms-interacting protein
113 THOC6interactor150.64843.379WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
Ge1_WD40 (PF16529, IPR032401): WD40 region of Ge1, enhancer of mRNA-decapping protein
114 THOC7interactor120.7129.835EcoEI_R_C (PF08463, IPR013670): EcoEI R protein C-terminal
THOC7 (PF05615, IPR008501): Tho complex subunit 7
UPF0193 (PF05250, IPR007914): Uncharacterised protein family (UPF0193)
115 TMEM176Ainteractor21.0000CD20 (PF04103, IPR007237): CD20-like family
116 TUBB3interactor60.7332.030Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
117 TXNL1interactor60.60010.207PITH (PF06201, IPR010400): PITH domain
Thioredoxin (PF00085, IPR013766): Thioredoxin
118 U2AF2protein found in more fusions240.399177.859RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Transformer (PF06495, IPR010519): Fruit fly transformer protein
119 UBCprotein found in more fusions250.250425.642ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
120 UBE3Aoncoprotein100.41738.288HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
PCM1_C (PF15717, IPR031446): Pericentriolar material 1 C terminus
AZUL (PF16558, IPR032353): Amino-terminal Zinc-binding domain of ubiquitin ligase E3A
121 UQCRC2oncoprotein140.429166.279Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16)
Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain
122 VCAM1interactor160.258117.160C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
123 VPS33Binteractor41.0000Sec1 (PF00995, IPR001619): Sec1 family
124 WDR74interactor31.0000WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
125 WWOXsuppressor100.244103.186adh_short (PF00106, IPR002198): short chain dehydrogenase
WW (PF00397, IPR001202, SM00456): WW domain
126 YWHAGprotein found in more fusions210.311181.76614-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein

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