Find Fusion Network

Enter
Fusion ID:
Protein names:


Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins DSC2, GDAP1L1 (from a repository: Mon Jul 29 00:31:28 2019)
Examples

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Circle
Radial
Force Directed
Preset
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)15
The number (and %) of the onco-proteins3 (20.00 %)
The number (and %) of the tumor suppressors1 (6.67 %)
Total number of binary PPIs (saturation %)34 (32.38 %)
The number (and %) of affected PPIs13 (38.24 %)
The number of possible different fusions1
PPI diameter2
PPI radiusinf
The average degree of PPI4.133
Assortativity coefficient-0.1291
The network average Clustering coefficient0.543
The number (and %) of a zero Clustering coefficients3 (20.00 %)
The number (and %) of a zero Betweenness Centrality5 (33.33 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: DSC2,GDAP1L1 All fusions
Proteins found in more fusions

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 DSC2parental protein130.23192.667Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region
Cadherin_pro (PF08758, IPR014868, SM01055): Cadherin prodomain like
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
Cadherin_3 (PF16184): Cadherin-like
2 GDAP1L1interactor000Nsp1 (PF11501, IPR021590): Non structural protein Nsp1
GST_C_2 (PF13410): Glutathione S-transferase, C-terminal domain
GST_N_3 (PF13417, IPR004045): Glutathione S-transferase, N-terminal domain
3 CLK1interactor200PDGF_N (PF04692, IPR006782): Platelet-derived growth factor, N terminal region
Pkinase (PF00069, IPR000719): Protein kinase domain
4 CSNK2A2interactor100Pkinase (PF00069, IPR000719): Protein kinase domain
5 DSG1interactor40.8330.500Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
Cadherin_3 (PF16184): Cadherin-like
6 DSG2oncoprotein70.4769.833BAT2_N (PF07001, IPR009738): BAT2 N-terminus
Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
Cadherin_3 (PF16184): Cadherin-like
7 ELAVL1oncoprotein60.4005.667RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
8 GMCL1interactor40.6671.000BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
9 JUPsuppressor70.5717.333Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
10 PKP2interactor50.8001.167Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
DUF383 (PF04063, IPR007205): Domain of unknown function (DUF383)
11 PKP3interactor40.8330.500Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
DUF383 (PF04063, IPR007205): Domain of unknown function (DUF383)
12 RYKoncoprotein30.6670.667Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
WIF (PF02019, IPR003306, SM00469): WIF domain
13 SKA1interactor21.0000SKA1 (PF07160, IPR009829): Spindle and kinetochore-associated protein 1
14 TMEM17interactor41.0000Transmemb_17 (PF09799, IPR019184): Predicted membrane protein
DUF3043 (PF11241, IPR021403): Protein of unknown function (DUF3043)
15 TMEM216interactor30.6670.667Transmemb_17 (PF09799, IPR019184): Predicted membrane protein

B a c k    t o    T o p ⇑