1 |
GOSR1 | parental protein | 26 | 0.231 | 808.882 | V-SNARE_C (PF12352): Snare region anchored in the vesicle membrane C-terminus Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein |
2 |
YES1 | parental protein | 85 | 0.052 | 7548.862 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain YdjC (PF04794, IPR006879): YdjC-like protein SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
3 |
ACSL3 | oncoprotein | 5 | 0.400 | 20.223 | AMP-binding (PF00501, IPR000873): AMP-binding enzyme AMP-binding_C (PF13193, IPR025110): AMP-binding enzyme C-terminal domain |
4 |
ADAM15 | interactor | 2 | 1.000 | 0 | CD20 (PF04103, IPR007237): CD20-like family Pep_M12B_propep (PF01562, IPR002870): Reprolysin family propeptide Reprolysin (PF01421, IPR001590): Reprolysin (M12B) family zinc metalloprotease ADAM_CR (PF08516, IPR006586, SM00608): ADAM cysteine-rich Disintegrin (PF00200, IPR001762, SM00050): Disintegrin |
5 |
ANKRD12 | oncoprotein | 2 | 1.000 | 0 | CDK5_activator (PF03261, IPR004944): Cyclin-dependent kinase 5 activator protein GAGA_bind (PF06217, IPR010409): GAGA binding protein-like family DUF2370 (PF10176, IPR019325): Protein of unknown function (DUF2370) Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies) UPF0767 (PF15990, IPR031933): UPF0767 family PNISR (PF15996, IPR031937): Arginine/serine-rich protein PNISR |
6 |
ANLN | oncoprotein | 7 | 0.714 | 3.047 | Anillin (PF08174, IPR012966): Cell division protein anillin PH (PF00169, IPR001849, SM00233): PH domain Anillin_N (PF16018, IPR031970): Anillin N-terminus |
7 |
APP | protein found in more fusions | 25 | 0.105 | 678.714 | APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP) BUD22 (PF09073, IPR015158): BUD22 IncA (PF04156, IPR007285): IncA protein Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein |
8 |
ARRB1 | interactor | 11 | 0.291 | 82.849 | Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain |
9 |
ATAD1 | interactor | 5 | 0.400 | 23.525 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) PhoH (PF02562, IPR003714): PhoH-like protein DUF3240 (PF11582, IPR021634): Protein of unknown function (DUF3240) AAA_18 (PF13238): AAA domain |
10 |
ATP6AP2 | interactor | 7 | 0.533 | 12.526 | Phosphodiest (PF01663, IPR002591): Type I phosphodiesterase / nucleotide pyrophosphatase Renin_r (PF07850, IPR012493): Renin receptor-like protein |
11 |
ATP6V1E1 | interactor | 3 | 0.333 | 21.154 | vATP-synt_E (PF01991, IPR002842): ATP synthase (E/31 kDa) subunit |
12 |
BECN1 | suppressor | 5 | 0.500 | 1.086 | APG6 (PF04111, IPR007243): Autophagy protein Apg6 Ima1_N (PF09779, IPR018617): Ima1 N-terminal domain BH3 (PF15285, IPR029318): Beclin-1 BH3 domain, Bcl-2-interacting |
13 |
BET1 | interactor | 7 | 0.810 | 2.857 | Use1 (PF09753, IPR019150): Membrane fusion protein Use1 |
14 |
BET1L | interactor | 6 | 0.733 | 9.011 | CDV3 (PF15359, IPR026806): Carnitine deficiency-associated protein 3 |
15 |
C1orf94 | interactor | 3 | 0 | 34.457 | DUF4688 (PF15752, IPR031496): Domain of unknown function (DUF4688) |
16 |
CBL | suppressor | 10 | 0.389 | 23.730 | Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1 Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain Prok-RING_4 (PF14447): Prokaryotic RING finger family 4 zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain |
17 |
CCNL2 | interactor | 2 | 1.000 | 0 | Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term |
18 |
CCR1 | oncoprotein | 1 | 0 | 0 | 7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) |
19 |
CD36 | interactor | 3 | 0.333 | 7.318 | CD36 (PF01130, IPR002159): CD36 family |
20 |
CD46 | oncoprotein | 1 | 0 | 0 | Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region Sushi (PF00084, IPR000436, SM00032): Sushi repeat (SCR repeat) DUF3188 (PF11384, IPR021524): Protein of unknown function (DUF3188) ECSCR (PF15820, IPR026247): Endothelial cell-specific chemotaxis regulator |
21 |
CDH1 | suppressor | 7 | 0.667 | 3.378 | Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region Cadherin_pro (PF08758, IPR014868, SM01055): Cadherin prodomain like Cadherin (PF00028, IPR002126, SM00112): Cadherin domain |
22 |
CLEC12A | interactor | 3 | 1.000 | 0 | Ly49 (PF08391, IPR013600): Ly49-like protein, N-terminal region Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain |
23 |
CSF1R | oncoprotein | 6 | 0.533 | 3.419 | ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain |
24 |
CTNND1 | suppressor | 8 | 0.357 | 59.113 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Ebp2 (PF05890, IPR008610): Eukaryotic rRNA processing protein EBP2 Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain |
25 |
CUL7 | protein found in more fusions | 13 | 0.288 | 95.437 | ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7 |
26 |
CYP51A1 | interactor | 3 | 0.667 | 0.402 | p450 (PF00067, IPR001128): Cytochrome P450 |
27 |
DBN1 | oncoprotein | 10 | 0.556 | 15.208 | Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein CAF-1_p150 (PF11600): Chromatin assembly factor 1 complex p150 subunit, N-terminal MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c |
28 |
DOK1 | suppressor | 5 | 0.667 | 3.763 | IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type) PH (PF00169, IPR001849, SM00233): PH domain |
29 |
DSC1 | interactor | 2 | 1.000 | 0 | Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region Cadherin_pro (PF08758, IPR014868, SM01055): Cadherin prodomain like UPF0114 (PF03350, IPR005134): Uncharacterized protein family, UPF0114 Cadherin (PF00028, IPR002126, SM00112): Cadherin domain |
30 |
DVL2 | interactor | 8 | 0.333 | 17.223 | DEP (PF00610, IPR000591, SM00049): Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Dishevelled (PF02377, IPR003351): Dishevelled specific domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) DIX (PF00778, IPR001158, SM00021): DIX domain Dsh_C (PF12316, IPR024580): Segment polarity protein dishevelled (Dsh) C terminal |
31 |
DYNLT1 | interactor | 4 | 0.333 | 13.912 | Tctex-1 (PF03645, IPR005334): Tctex-1 family |
32 |
EGFR | oncoprotein | 26 | 0.157 | 557.604 | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT) GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV |
33 |
ELAVL1 | oncoprotein | 25 | 0.145 | 560.472 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
34 |
EPHB2 | suppressor | 3 | 1.000 | 0 | EGF_2 (PF07974, IPR013111): EGF-like domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) Ephrin_lbd (PF01404, IPR001090, SM00615): Ephrin receptor ligand binding domain cEGF (PF12662, IPR026823): Complement Clr-like EGF-like EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain |
35 |
FAF2 | interactor | 6 | 0.400 | 39.498 | DUF1682 (PF07946, IPR012879): Protein of unknown function (DUF1682) UBX (PF00789, IPR001012, SM00166): UBX domain Thioredoxin_7 (PF13899): Thioredoxin-like UBA_4 (PF14555): UBA-like domain |
36 |
FASLG | interactor | 3 | 0.667 | 0.957 | PAP_PilO (PF06864, IPR009663): Pilin accessory protein (PilO) TNF (PF00229, IPR006052, SM00207): TNF(Tumour Necrosis Factor) family PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
37 |
FLOT1 | interactor | 12 | 0.288 | 183.101 | CrtC (PF07143, IPR010791): CrtC N-terminal lipocalin domain Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family Flot (PF15975, IPR031905): Flotillin |
38 |
FN1 | oncoprotein | 18 | 0.229 | 323.498 | fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) |
39 |
FUNDC1 | interactor | 1 | 0 | 0 | FUN14 (PF04930, IPR007014): FUN14 family |
40 |
FXR2 | protein found in more fusions | 7 | 0.400 | 20.047 | Agenet (PF05641, IPR008395, SM00743): Agenet domain REV (PF00424, IPR000625): REV protein (anti-repression trans-activator protein) KH_1 (PF00013, IPR004088, SM00322): KH domain FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2 |
41 |
FYN | oncoprotein | 29 | 0.101 | 357.496 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
42 |
FYTTD1 | interactor | 2 | 0 | 0 | FYTT (PF07078, IPR009782): Forty-two-three protein |
43 |
GPR35 | interactor | 1 | 0 | 0 | 7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) |
44 |
GRPEL2 | interactor | 2 | 1.000 | 0 | GrpE (PF01025, IPR000740): GrpE GOLGA2L5 (PF15070, IPR024858): Putative golgin subfamily A member 2-like protein 5 |
45 |
HNRNPH1 | oncoprotein | 10 | 0.356 | 105.305 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger |
46 |
HOXB5 | interactor | 2 | 1.000 | 0 | DUF739 (PF05339, IPR008003): Protein of unknown function (DUF739) Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
47 |
HSP90AA1 | oncoprotein | 16 | 0.314 | 92.055 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein |
48 |
ILF2 | interactor | 7 | 0.524 | 33.334 | DZF (PF07528, IPR006561, SM00572): DZF domain |
49 |
JSRP1 | interactor | 1 | 0 | 0 | SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal JSRP (PF15312, IPR026178): Junctional sarcoplasmic reticulum protein PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
50 |
KHDRBS1 | protein found in more fusions | 7 | 0.267 | 68.137 | KH_1 (PF00013, IPR004088, SM00322): KH domain Qua1 (PF16274, IPR032571): Qua1 domain Sam68-YY (PF16568, IPR032335): Tyrosine-rich domain of Sam68 |
51 |
KIT | oncoprotein | 3 | 0.667 | 0.667 | ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain |
52 |
LIMA1 | suppressor | 14 | 0.363 | 85.984 | LIM (PF00412, IPR001781, SM00132): LIM domain ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain |
53 |
LIMCH1 | interactor | 6 | 0.533 | 14.185 | LIM (PF00412, IPR001781, SM00132): LIM domain MAS20 (PF02064, IPR002056): MAS20 protein import receptor DUF3435 (PF11917, IPR021842): Protein of unknown function (DUF3435) DUF4757 (PF15949, IPR031865): Domain of unknown function (DUF4757) |
54 |
MAPRE1 | oncoprotein | 8 | 0.381 | 18.775 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain EB1 (PF03271, IPR004953): EB1-like C-terminal motif SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3 |
55 |
MED28 | interactor | 4 | 0.667 | 1.189 | cwf21 (PF08312, IPR013170, SM01115): cwf21 domain Med28 (PF11594, IPR021640): Mediator complex subunit 28 |
56 |
MYC | oncoprotein | 10 | 0.278 | 220.201 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region |
57 |
MYH9 | suppressor | 15 | 0.343 | 127.668 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) |
58 |
NEDD4 | suppressor | 10 | 0.333 | 19.645 | Rota_NS26 (PF01525, IPR002512): Rotavirus NS26 WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) |
59 |
NFKBIA | oncoprotein | 4 | 0.667 | 1.167 | Ank (PF00023, IPR002110, SM00248): Ankyrin repeat Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies) |
60 |
NIF3L1 | interactor | 4 | 1.000 | 0 | NIF3 (PF01784, IPR002678): NIF3 (NGG1p interacting factor 3) |
61 |
NPHS1 | interactor | 3 | 1.000 | 0 | C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain DUF4643 (PF15485, IPR028004): Domain of unknown function (DUF4643) |
62 |
NSF | interactor | 11 | 0.511 | 83.548 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2 CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain ATPase (PF06745, IPR014774): KaiC AAA_19 (PF13245): AAA domain |
63 |
NSUN2 | interactor | 3 | 0.667 | 1.389 | Methyltr_RsmB-F (PF01189, IPR001678): 16S rRNA methyltransferase RsmB/F |
64 |
OCLN | interactor | 3 | 0.333 | 13.289 | MARVEL (PF01284, IPR008253): Membrane-associating domain Occludin_ELL (PF07303, IPR010844): Occludin homology domain EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal |
65 |
OGT | interactor | 4 | 0.500 | 2.500 | TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat Glyco_transf_41 (PF13844, IPR029489): Glycosyl transferase family 41 TPR_19 (PF14559): Tetratricopeptide repeat |
66 |
OLIG1 | interactor | 2 | 1.000 | 0 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446) Metal_resist (PF13801, IPR025961): Heavy-metal resistance |
67 |
PAN2 | interactor | 10 | 0.422 | 20.614 | RNase_T (PF00929, IPR013520): Exonuclease UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase WD40_like (PF17005, IPR031544): WD40-like domain |
68 |
PDCD6IP | interactor | 6 | 0.700 | 2.196 | BRO1 (PF03097, IPR004328, SM01041): BRO1-like domain MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c ALIX_LYPXL_bnd (PF13949, IPR025304): ALIX V-shaped domain binding to HIV |
69 |
PDLIM7 | interactor | 6 | 0.400 | 9.120 | LIM (PF00412, IPR001781, SM00132): LIM domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein DUF4749 (PF15936, IPR031847): Domain of unknown function (DUF4749) |
70 |
PECAM1 | oncoprotein | 3 | 1.000 | 0 | C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain V-set_CD47 (PF08204, IPR013270): CD47 immunoglobulin-like domain Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain MAP17 (PF15807, IPR031627): Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 |
71 |
PHB2 | interactor | 5 | 0.600 | 7.589 | DUF2605 (PF10792, IPR019728): Protein of unknown function (DUF2605) Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family |
72 |
PIFO | interactor | 1 | 0 | 0 | SHIPPO-rpt (PF07004, IPR010736): Sperm-tail PG-rich repeat |
73 |
PKP1 | interactor | 3 | 0.333 | 50.759 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat |
74 |
PPP1CB | interactor | 11 | 0.436 | 30.083 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain |
75 |
PTEN | suppressor | 10 | 0.311 | 26.082 | DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein |
76 |
PTK2 | protein found in more fusions | 12 | 0.436 | 33.181 | FERM_M (PF00373, IPR019748): FERM central domain Focal_AT (PF03623, IPR005189): Focal adhesion targeting region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase UCMA (PF17085, IPR031386): Unique cartilage matrix associated protein |
77 |
PTPN1 | suppressor | 6 | 0.200 | 27.955 | Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase |
78 |
RAB5C | oncoprotein | 12 | 0.273 | 97.391 | Ras (PF00071, IPR001806, SM00173): Ras family |
79 |
RASA1 | oncoprotein | 9 | 0.333 | 58.762 | C2 (PF00168, IPR000008, SM00239): C2 domain PH (PF00169, IPR001849, SM00233): PH domain RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
80 |
RPL10 | suppressor | 8 | 0.321 | 20.481 | Ribosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e |
81 |
SCFD1 | interactor | 12 | 0.394 | 84.021 | Sec1 (PF00995, IPR001619): Sec1 family |
82 |
SEC22B | interactor | 8 | 0.393 | 42.157 | Synaptobrevin (PF00957, IPR001388): Synaptobrevin Longin (PF13774, IPR010908): Regulated-SNARE-like domain |
83 |
SLC16A14 | interactor | 1 | 0 | 0 | MFS_1 (PF07690, IPR011701): Major Facilitator Superfamily |
84 |
SLC25A11 | protein found in more fusions | 5 | 0.500 | 3.445 | Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein |
85 |
SLC25A41 | interactor | 2 | 1.000 | 0 | Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein |
86 |
SLC30A4 | interactor | 1 | 0 | 0 | Cation_efflux (PF01545, IPR002524): Cation efflux family |
87 |
SLC9A3R1 | suppressor | 3 | 1.000 | 0 | EBP50_C (PF09007, IPR015098): EBP50, C-terminal PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) |
88 |
SNAP23 | interactor | 15 | 0.407 | 387.667 | DivIC (PF04977, IPR007060): Septum formation initiator DUF16 (PF01519, IPR002862): Protein of unknown function DUF16 SNAP-25 (PF00835, IPR000928): SNAP-25 family DUF5089 (PF17002, IPR031547): Domain of unknown function (DUF5089) |
89 |
SNAP25 | interactor | 6 | 0.600 | 17.345 | SNAP-25 (PF00835, IPR000928): SNAP-25 family Use1 (PF09753, IPR019150): Membrane fusion protein Use1 |
90 |
SOCS3 | suppressor | 9 | 0.417 | 33.594 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SOCS_box (PF07525, IPR001496): SOCS box |
91 |
SPRR2A | interactor | 1 | 0 | 0 | SPRR2 (PF14820, IPR029142): Small proline-rich 2 |
92 |
SSBP3 | oncoprotein | 2 | 0 | 4.483 | SSDP (PF04503): Single-stranded DNA binding protein, SSDP |
93 |
STX12 | interactor | 13 | 0.513 | 119.029 | PEP-utilisers_N (PF05524, IPR008731): PEP-utilising enzyme, N-terminal SNARE (PF05739, IPR000727, SM00397): SNARE domain DUF2776 (PF10951, IPR021240): Protein of unknown function (DUF2776) Syntaxin_2 (PF14523): Syntaxin-like protein |
94 |
STX3 | interactor | 8 | 0.500 | 43.551 | XhlA (PF10779, IPR019715): Haemolysin XhlA Syntaxin (PF00804, IPR006011, SM00503): Syntaxin SNARE (PF05739, IPR000727, SM00397): SNARE domain |
95 |
STX5 | interactor | 17 | 0.463 | 110.837 | Apolipoprotein (PF01442, IPR000074): Apolipoprotein A1/A4/E domain CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Syntaxin-18_N (PF10496, IPR019529): SNARE-complex protein Syntaxin-18 N-terminus Syntaxin (PF00804, IPR006011, SM00503): Syntaxin SNARE (PF05739, IPR000727, SM00397): SNARE domain Syntaxin-5_N (PF11416, IPR021538): Syntaxin-5 N-terminal, Sly1p-binding domain |
96 |
STX6 | interactor | 11 | 0.655 | 55.261 | Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal SNARE (PF05739, IPR000727, SM00397): SNARE domain |
97 |
STX7 | interactor | 13 | 0.551 | 59.658 | SNARE (PF05739, IPR000727, SM00397): SNARE domain Cep57_CLD_2 (PF14197, IPR025925): Centrosome localisation domain of PPC89 Syntaxin_2 (PF14523): Syntaxin-like protein |
98 |
THAP1 | interactor | 6 | 0.300 | 19.480 | THAP (PF05485, IPR006612, SM00980): THAP domain Tho2 (PF11262, IPR021418): Transcription factor/nuclear export subunit protein 2 Cep57_CLD (PF14073, IPR025913): Centrosome localisation domain of Cep57 |
99 |
TMEM17 | interactor | 19 | 0.263 | 830.270 | Transmemb_17 (PF09799, IPR019184): Predicted membrane protein DUF3043 (PF11241, IPR021403): Protein of unknown function (DUF3043) |
100 |
TMEM185A | interactor | 3 | 0.333 | 67.186 | Tmemb_185A (PF10269, IPR019396): Transmembrane Fragile-X-F protein |
101 |
TMEM216 | interactor | 19 | 0.263 | 203.974 | Transmemb_17 (PF09799, IPR019184): Predicted membrane protein |
102 |
TNFSF11 | interactor | 1 | 0 | 0 | TNF (PF00229, IPR006052, SM00207): TNF(Tumour Necrosis Factor) family DUF2735 (PF10931, IPR021232): Protein of unknown function (DUF2735) |
103 |
TNK2 | protein found in more fusions | 6 | 0.800 | 1.179 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal GTPase_binding (PF09027, IPR015116): GTPase binding Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Inhibitor_Mig-6 (PF11555, IPR021619): EGFR receptor inhibitor Mig-6 UBA_4 (PF14555): UBA-like domain SH3_9 (PF14604, IPR001452): Variant SH3 domain |
104 |
TRAF2 | interactor | 10 | 0.306 | 31.136 | MATH (PF00917, IPR002083, SM00061): MATH domain Sina (PF03145, IPR018121): Seven in absentia protein family SlyX (PF04102, IPR007236): SlyX zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain zf-C3HC4_5 (PF17121, IPR001841): Zinc finger, C3HC4 type (RING finger) |
105 |
TRAF6 | protein found in more fusions | 9 | 0.286 | 28.914 | SlyX (PF04102, IPR007236): SlyX zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) |
106 |
TRPV4 | interactor | 2 | 1.000 | 0 | Ion_trans (PF00520, IPR005821): Ion transport protein Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) |
107 |
TSR1 | interactor | 2 | 1.000 | 0 | AARP2CN (PF08142, IPR012948, SM00785): AARP2CN (NUC121) domain RIBIOP_C (PF04950, IPR007034): 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal NUSAP (PF16006, IPR026756): Nucleolar and spindle-associated protein |
108 |
USO1 | interactor | 9 | 0.429 | 69.020 | Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region Uso1_p115_head (PF04869, IPR006953): Uso1 / p115 like vesicle tethering protein, head region Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain MutS_III (PF05192, IPR007696, SM00533): MutS domain III ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding MG1 (PF11974, IPR021868): Alpha-2-macroglobulin MG1 domain TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding |
109 |
VAPA | interactor | 10 | 0.356 | 68.101 | DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) UL45 (PF05473, IPR008646): UL45 protein, carbohydrate-binding C-type lectin-like Motile_Sperm (PF00635, IPR000535): MSP (Major sperm protein) domain |
110 |
YKT6 | interactor | 10 | 0.533 | 33.175 | Synaptobrevin (PF00957, IPR001388): Synaptobrevin Longin (PF13774, IPR010908): Regulated-SNARE-like domain |
111 |
ZBTB8A | interactor | 4 | 0.667 | 0.500 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein Zn_Tnp_IS1595 (PF12760, IPR024442): Transposase zinc-ribbon domain zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger |
112 |
ZNF512B | interactor | 1 | 0 | 0 | YTV (PF07639, IPR011521): YTV zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2HC5 (PF06221, IPR009349): Putative zinc finger motif, C2HC5-type zf-Nse (PF11789, IPR004181): Zinc-finger of the MIZ type in Nse subunit Zn_Tnp_IS1595 (PF12760, IPR024442): Transposase zinc-ribbon domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2H2_aberr (PF17017, IPR031514): Aberrant zinc-finger |