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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)210
The number (and %) of the onco-proteins57 (27.14 %)
The number (and %) of the tumor suppressors17 (8.10 %)
Total number of binary PPIs (saturation %)1165 (5.31 %)
The number (and %) of affected PPIs209 (17.94 %)
The number of possible different fusions30
PPI diameter4
PPI radius2
The average degree of PPI10.457
Assortativity coefficient-0.3876
The network average Clustering coefficient0.379
The number (and %) of a zero Clustering coefficients54 (25.71 %)
The number (and %) of a zero Betweenness Centrality62 (29.52 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: TFIP11,VTN All fusions
Proteins found in more fusions PRPF19 (see 2 fusions); CUL7 (see 2 fusions); SMARCB1 (see 12 fusions); SSX2IP (see 1 fusions); CEP57L1 (see 1 fusions); NDC80 (see 1 fusions); COPS5 (see 1 fusions); TXLNA (see 3 fusions); NDE1 (see 3 fusions); DDX5 (see 1 fusions); PRPF40A (see 2 fusions); IK (see 1 fusions); TP53 (see 3 fusions); THAP7 (see 1 fusions); HOOK1 (see 2 fusions); PRPF3 (see 1 fusions); SNW1 (see 1 fusions); APP (see 5 fusions); LMNA (see 4 fusions); SFPQ (see 6 fusions); PRDX4 (see 1 fusions); VEGFA (see 1 fusions); DSP (see 4 fusions); PRPF8 (see 3 fusions); SRSF1 (see 1 fusions); LUC7L3 (see 1 fusions); ADH5 (see 3 fusions); DDB1 (see 4 fusions); TNNT1 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 TFIP11parental protein1320.02323493.778G-patch (PF01585, IPR000467, SM00443): G-patch domain
GCFC (PF07842, IPR022783): GC-rich sequence DNA-binding factor-like protein
TIP_N (PF12457, IPR022159): Tuftelin interacting protein N terminal
2 VTNparental protein770.1227943.426Hemopexin (PF00045, IPR018487, SM00120): Hemopexin
Somatomedin_B (PF01033, IPR001212, SM00201): Somatomedin B domain
3 ABI2suppressor80.33346.322Abi_HHR (PF07815, IPR012849): Abl-interactor HHR
NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region
SH3_9 (PF14604, IPR001452): Variant SH3 domain
TMEM171 (PF15471, IPR029173): Transmembrane protein family 171
ATP-synt_ab_Xtn (PF16886, IPR031686): ATPsynthase alpha/beta subunit N-term extension
4 ADH5protein found in more fusions50.5009.886ADH_N (PF08240, IPR013154): Alcohol dehydrogenase GroES-like domain
ADH_zinc_N (PF00107, IPR013149): Zinc-binding dehydrogenase
ADH_zinc_N_2 (PF13602): Zinc-binding dehydrogenase
5 ADTRPinteractor100Far-17a_AIG1 (PF04750, IPR006838): FAR-17a/AIG1-like protein
6 AIMP2suppressor60.30027.181GST_C_2 (PF13410): Glutathione S-transferase, C-terminal domain
GST_C_3 (PF14497, IPR004046): Glutathione S-transferase, C-terminal domain
AIMP2_LysRS_bd (PF16780, IPR031889): AIMP2 lysyl-tRNA synthetase binding domain
7 ALS2CR11interactor21.0000DUF2680 (PF10925, IPR024485): Protein of unknown function (DUF2680)
ALS2CR11 (PF15729, IPR031462): Amyotrophic lateral sclerosis 2 candidate 11
8 AMPHoncoprotein100BAR (PF03114, IPR004148, SM00721): BAR domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
PBP_N (PF17093, IPR031375): Penicillin-binding protein N-terminus
9 ANKRD11interactor30.6671.405DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
Pap_E4 (PF02711, IPR003861): E4 protein
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
DUF3408 (PF11888, IPR021823): Protein of unknown function (DUF3408)
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
AAA_11 (PF13086): AAA domain
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
10 APPprotein found in more fusions500.0573416.616APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
11 ARMCX1oncoprotein100Arm_2 (PF04826, IPR006911): Armadillo-like
12 ARNT2interactor80.25069.821HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
PAS (PF00989, IPR013767, SM00091): PAS fold
PAS_3 (PF08447, IPR013655): PAS fold
PAP2 (PF01569, IPR000326, SM00014): PAP2 superfamily
13 ATP5POinteractor50.300100.035OSCP (PF00213, IPR000711): ATP synthase delta (OSCP) subunit
14 BMFsuppressor100BMF (PF15185, IPR028192): Bcl-2-modifying factor, apoptosis
15 BMI1oncoprotein210.216573.171zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
16 BUD31interactor80.42929.529G10 (PF01125, IPR001748): G10 protein
17 C1orf109interactor40.5002.284CK2S (PF15011, IPR029159): Casein Kinase 2 substrate
18 CARD9interactor120.27339.823CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
IncA (PF04156, IPR007285): IncA protein
NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein
19 CBX1interactor31.0000Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
Chromo_shadow (PF01393, IPR008251, SM00300): Chromo shadow domain
20 CCDC116interactor100DUF4702 (PF15774, IPR031532): Domain of unknown function (DUF4702)
21 CCDC121interactor100DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Methyltransf_32 (PF13679, IPR025714): Methyltransferase domain
DUF4515 (PF14988, IPR032777): Domain of unknown function (DUF4515)
22 CCDC146interactor21.0000ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724)
DUF745 (PF05335, IPR007999): Protein of unknown function (DUF745)
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
Med21 (PF11221, IPR021384): Subunit 21 of Mediator complex
Kinetocho_Slk19 (PF12709, IPR024312): Central kinetochore-associated
FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain
BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
23 CCDC151interactor2051.962DUF16 (PF01519, IPR002862): Protein of unknown function DUF16
Radial_spoke_3 (PF06098, IPR009290): Radial spoke protein 3
SAE2 (PF08573, IPR013882): DNA repair protein endonuclease SAE2/CtIP C-terminus
DUF2721 (PF11026, IPR021279): Protein of unknown function (DUF2721)
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
DUF4140 (PF13600, IPR025554): N-terminal domain of unknown function (DUF4140)
Nup54 (PF13874, IPR025712): Nucleoporin complex subunit 54
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
24 CCDC42interactor100Hom_end_hint (PF05203, IPR007868): Hom_end-associated Hint
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
25 CCDC68interactor21.0000bZIP_1 (PF00170, IPR004827): bZIP transcription factor
Med9 (PF07544, IPR011425): RNA polymerase II transcription mediator complex subunit 9
Spore_YhcN_YlaJ (PF09580, IPR019076): Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
26 CCHCR1interactor80.4768.365HCR (PF07111, IPR009800): Alpha helical coiled-coil rod protein (HCR)
27 CCND3oncoprotein3033.539Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
28 CCNG1oncoprotein60.46720.508Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
29 CCNL1interactor2015.903Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
DUF936 (PF06075, IPR010341): Plant protein of unknown function (DUF936)
30 CD247interactor100ITAM (PF02189, IPR003110, SM00077): Immunoreceptor tyrosine-based activation motif
TCR_zetazeta (PF11628, IPR021663): T-cell surface glycoprotein CD3 zeta chain
31 CDC5Linteractor460.3241060.858OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component
Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
32 CENPUinteractor100Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain
XhlA (PF10779, IPR019715): Haemolysin XhlA
CENP-U (PF13097, IPR025214): CENP-A nucleosome associated complex (NAC) subunit
33 CEP57interactor80.179147.397Cep57_MT_bd (PF06657, IPR024957): Centrosome microtubule-binding domain of Cep57
Tup_N (PF08581, IPR013890): Tup N-terminal
CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit
Cep57_CLD (PF14073, IPR025913): Centrosome localisation domain of Cep57
TRIQK (PF15168, IPR024842): Triple QxxK/R motif-containing protein family
34 CEP57L1protein found in more fusions120.21841.068Cep57_MT_bd (PF06657, IPR024957): Centrosome microtubule-binding domain of Cep57
XhlA (PF10779, IPR019715): Haemolysin XhlA
YqzE (PF14038, IPR025622): YqzE-like protein
Cep57_CLD (PF14073, IPR025913): Centrosome localisation domain of Cep57
35 CFAP206interactor31.0000THP2 (PF09432, IPR018557): Tho complex subunit THP2
DUF3508 (PF12018, IPR021897): Domain of unknown function (DUF3508)
36 CKS2oncoprotein200CKS (PF01111, IPR000789, SM01084): Cyclin-dependent kinase regulatory subunit
37 COMTD1interactor100FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
38 COPS5protein found in more fusions390.292643.827JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
39 COQ8Ainteractor31.0000ABC1 (PF03109, IPR004147): ABC1 family
CbtA (PF09490, IPR012666): Probable cobalt transporter subunit (CbtA)
40 COX5Binteractor30.6670.071COX5B (PF01215, IPR002124): Cytochrome c oxidase subunit Vb
41 CRADDinteractor21.0000CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain
Death (PF00531, IPR000488, SM00005): Death domain
42 CUL7protein found in more fusions480.265928.551ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
Cullin (PF00888, IPR001373, SM00182): Cullin family
DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918)
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
43 DDB1protein found in more fusions160.267160.635CPSF_A (PF03178, IPR004871): CPSF A subunit region
MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term
44 DDX23interactor150.552115.415DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
FUSC (PF04632, IPR006726): Fusaric acid resistance protein family
Transformer (PF06495, IPR010519): Fruit fly transformer protein
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
DUF3698 (PF12479, IPR022167): Protein of unknown function (DUF3698)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
45 DDX5oncoprotein240.636120.608DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
P68HR (PF08061, IPR012587): P68HR (NUC004) repeat
ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
46 DEKoncoprotein60.6671.455DEK_C (PF08766, IPR014876): DEK C terminal domain
Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family
SAP (PF02037, IPR003034, SM00513): SAP domain
Bud13 (PF09736, IPR018609): Pre-mRNA-splicing factor of RES complex
DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052)
TFIIE-A_C (PF11521, IPR021600): C-terminal general transcription factor TFIIE alpha
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
47 DGCR6interactor30.66715.903DGCR6 (PF07324, IPR010849): DiGeorge syndrome critical region 6 (DGCR6) protein
48 DHX15interactor280.463349.148DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
AAA_29 (PF13555): P-loop containing region of AAA domain
49 DHX9oncoprotein240.51492.066DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold
T2SSE (PF00437, IPR001482): Type II/IV secretion system protein
HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
50 DISC1interactor60.33332.048HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
Mnd1 (PF03962, IPR005647): Mnd1 family
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
Tropomyosin (PF00261, IPR000533): Tropomyosin
UVR (PF02151, IPR001943): UvrB/uvrC motif
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
51 DSPsuppressor90.50012.467APG6 (PF04111, IPR007243): Autophagy protein Apg6
ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
BRE1 (PF08647, IPR013956): BRE1 E3 ubiquitin ligase
CLP_protease (PF00574, IPR023562): Clp protease
DUF1192 (PF06698, IPR009579): Protein of unknown function (DUF1192)
DUF16 (PF01519, IPR002862): Protein of unknown function DUF16
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
Fez1 (PF06818): Fez1
FIVAR (PF07554, IPR011490): Uncharacterised Sugar-binding Domain
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
Occludin_ELL (PF07303, IPR010844): Occludin homology domain
Rho_Binding (PF08912, IPR015008): Rho Binding
Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Spectrin (PF00435, IPR002017): Spectrin repeat
TBPIP (PF07106, IPR010776): Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
Plectin (PF00681, IPR001101, SM00250): Plectin repeat
DUF2570 (PF10828, IPR022538): Protein of unknown function (DUF2570)
SOGA (PF11365, IPR027881): Protein SOGA
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
FAM184 (PF15665): Family with sequence similarity 184, A and B
JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
52 EEDsuppressor450.248775.083WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
53 EGFoncoprotein303.738EGF (PF00008, IPR000742, SM00181): EGF-like domain
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
SGL (PF08450, IPR013658): SMP-30/Gluconolaconase/LRE-like region
Ldl_recept_b (PF00058, IPR000033, SM00135): Low-density lipoprotein receptor repeat class B
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
EGF_3 (PF12947, IPR024731): EGF domain
FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site
DUF5050 (PF16472, IPR032485): Domain of unknown function (DUF5050)
54 EIF3Aoncoprotein30.33314.081DUF1003 (PF06210, IPR010406): Protein of unknown function (DUF1003)
Ly49 (PF08391, IPR013600): Ly49-like protein, N-terminal region
PCI (PF01399, IPR000717, SM00088): PCI domain
AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3
55 ETV7interactor100Ets (PF00178, IPR000418, SM00413): Ets-domain
SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain
56 FAM13Cinteractor200Mnd1 (PF03962, IPR005647): Mnd1 family
SlyX (PF04102, IPR007236): SlyX
MRI (PF15325, IPR028278): Modulator of retrovirus infection
Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease
57 FAM156Ainteractor100PGC7_Stella (PF15549, IPR029096): PGC7/Stella/Dppa3 domain
58 FAM161Ainteractor70.5335.189YajC (PF02699, IPR003849): Preprotein translocase subunit
UPF0564 (PF10595, IPR019579): Uncharacterised protein family UPF0564
59 FAM50Binteractor21.0000Atrophin-1 (PF03154, IPR002951): Atrophin-1 family
XAP5 (PF04921, IPR007005): XAP5, circadian clock regulator
60 FGF2oncoprotein100FGF (PF00167, IPR002209, SM00442): Fibroblast growth factor
61 FGL1interactor100Fibrinogen_C (PF00147, IPR002181, SM00186): Fibrinogen beta and gamma chains, C-terminal globular domain
62 GCC1interactor50.40064.363DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC)
GRIP (PF01465, IPR000237, SM00755): GRIP domain
IFP_35_N (PF07334, IPR009938): Interferon-induced 35 kDa protein (IFP 35) N-terminus
LPP (PF04728, IPR006817): Lipoprotein leucine-zipper
DUF2335 (PF10097, IPR019284): Predicted membrane protein (DUF2335)
Kinetocho_Slk19 (PF12709, IPR024312): Central kinetochore-associated
Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit
FAM184 (PF15665): Family with sequence similarity 184, A and B
63 GEMinteractor30.3331307.192Ras (PF00071, IPR001806, SM00173): Ras family
AAA_22 (PF13401, IPR003593): AAA domain
64 GINM1interactor100NA
65 GLUD1interactor30.3334.418ELFV_dehydrog (PF00208, IPR006096, SM00839): Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
ELFV_dehydrog_N (PF02812, IPR006097): Glu/Leu/Phe/Val dehydrogenase, dimerisation domain
SF3b10 (PF07189, IPR009846): Splicing factor 3B subunit 10 (SF3b10)
66 GNG4interactor100G-gamma (PF00631, IPR015898, SM00224): GGL domain
67 GOLGA1interactor21.0000GRIP (PF01465, IPR000237, SM00755): GRIP domain
Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
68 GOPConcoprotein5085.850DUF903 (PF06004, IPR010305): Bacterial protein of unknown function (DUF903)
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
DUF3209 (PF11483, IPR021577): Protein of unknown function (DUF3209)
69 GPS2oncoprotein30.6675.289G_path_suppress (PF15991, IPR026094): G-protein pathway suppressor
70 HAUS1interactor100.30662.636THP2 (PF09432, IPR018557): Tho complex subunit THP2
XhlA (PF10779, IPR019715): Haemolysin XhlA
DUF3496 (PF12001, IPR021885): Domain of unknown function (DUF3496)
71 HDAC11interactor50.40035.944Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
72 HMG20Binteractor30.66715.903IncA (PF04156, IPR007285): IncA protein
NEMP (PF10225, IPR019358): NEMP family
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
DUF3496 (PF12001, IPR021885): Domain of unknown function (DUF3496)
73 HNRNPMinteractor290.475233.512RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNP_M (PF11532, IPR024666): Heterogeneous nuclear ribonucleoprotein M
Collagen_mid (PF15984, IPR031929): Bacterial collagen, middle region
74 HNRNPRinteractor260.62550.710RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Limkain-b1 (PF11608, IPR024582): Limkain b1
75 HNRNPUinteractor410.339421.979CDC45 (PF02724, IPR003874): CDC45-like protein
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SAP (PF02037, IPR003034, SM00513): SAP domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
AAA_33 (PF13671): AAA domain
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
76 HOOK1protein found in more fusions307.622HOOK (PF05622, IPR008636): HOOK protein
77 HP1BP3interactor110.34565.135RXT2_N (PF08595, IPR013904): RXT2-like, N-terminal
SDA1 (PF05285, IPR007949): SDA1
YL1 (PF05764, IPR008895): YL1 nuclear protein
Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family
78 IGF2oncoprotein21.0000IGF2_C (PF08365, IPR013576): Insulin-like growth factor II E-peptide
Insulin (PF00049, IPR016179, SM00078): Insulin/IGF/Relaxin family
79 IGFBP5suppressor30.6671.000IGFBP (PF00219, IPR000867, SM00121): Insulin-like growth factor binding protein
Thyroglobulin_1 (PF00086, IPR000716, SM00211): Thyroglobulin type-1 repeat
80 IKprotein found in more fusions190.431137.671Lsm_interact (PF05391, IPR008669): Lsm interaction motif
RED_C (PF07807, IPR012492): RED-like protein C-terminal region
RED_N (PF07808, IPR012916): RED-like protein N-terminal region
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
81 IKBIPinteractor2015.903Fez1 (PF06818): Fez1
Occludin_ELL (PF07303, IPR010844): Occludin homology domain
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
SesA (PF17107, IPR031352): N-terminal domain on NACHT_NTPase and P-loop NTPases
82 IL16oncoprotein3073.575PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
SUZ (PF12752, IPR024771): SUZ domain
83 ILF2interactor130.67919.715DZF (PF07528, IPR006561, SM00572): DZF domain
84 ILF3oncoprotein210.500214.594dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
DZF (PF07528, IPR006561, SM00572): DZF domain
85 IMP3interactor30.33314.304Ribosomal_S4 (PF00163, IPR001912): Ribosomal protein S4/S9 N-terminal domain
S4 (PF01479, IPR002942, SM00363): S4 domain
86 ING3suppressor40.16740.866PHD (PF00628, IPR019787, SM00249): PHD-finger
Rifin_STEVOR (PF02009, IPR002858): Rifin/stevor family
ING (PF12998, IPR024610): Inhibitor of growth proteins N-terminal histone-binding
87 IQCF1interactor100IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
DUF3176 (PF11374, IPR021514): Protein of unknown function (DUF3176)
88 KANSL1interactor30.6677.622PEHE (PF15275, IPR029332): PEHE domain
89 KNG1interactor100Bradykinin (PF06753, IPR009608): Bradykinin
Chorion_2 (PF03964, IPR005649): Chorion family 2
Cystatin (PF00031, IPR000010, SM00043): Cystatin domain
90 KRT20interactor50.5002.600Duffy_binding (PF05424, IPR008602): Duffy binding domain
Filament (PF00038, IPR001664): Intermediate filament protein
91 KRT6Ainteractor3023.723Filament (PF00038, IPR001664): Intermediate filament protein
Keratin_2_head (PF16208, IPR032444): Keratin type II head
92 KRT6Binteractor30.33310.634Filament (PF00038, IPR001664): Intermediate filament protein
Keratin_2_head (PF16208, IPR032444): Keratin type II head
93 KRT6Cinteractor3030.398Filament (PF00038, IPR001664): Intermediate filament protein
Keratin_2_head (PF16208, IPR032444): Keratin type II head
94 KRT8interactor2013.856Filament (PF00038, IPR001664): Intermediate filament protein
Keratin_2_head (PF16208, IPR032444): Keratin type II head
95 LACRTinteractor30.66724.992NA
96 LATS1suppressor50.40042.329Cas_Cas6 (PF01881, IPR010156): CRISPR associated protein Cas6
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
97 LCA5interactor50.6003.758IncA (PF04156, IPR007285): IncA protein
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
Tantalus (PF15386, IPR028149): Drosophila Tantalus-like
Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease
98 LCA5Linteractor100DUF1515 (PF07439, IPR010889): Protein of unknown function (DUF1515)
Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
99 LENG1interactor50.40061.262Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR
DUF3323 (PF11796, IPR024466): Protein of unknown function N-terminus (DUF3323)
100 LIN37interactor100LIN37 (PF15306, IPR028226): LIN37
101 LINC00238interactor100MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
102 LMNAprotein found in more fusions190.379437.266Filament (PF00038, IPR001664): Intermediate filament protein
LTD (PF00932, IPR001322): Lamin Tail Domain
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
103 LMO1oncoprotein21.0000LIM (PF00412, IPR001781, SM00132): LIM domain
Vps39_2 (PF10367, IPR019453): Vacuolar sorting protein 39 domain 2
104 LMO4interactor50.40017.687LIM (PF00412, IPR001781, SM00132): LIM domain
zf-dskA_traR (PF01258, IPR000962): Prokaryotic dksA/traR C4-type zinc finger
105 LNX2interactor60.30084.851PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
DZR (PF12773, IPR025874): Double zinc ribbon
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
106 LSP1P3interactor100NA
107 LUC7L3protein found in more fusions160.43856.381LUC7 (PF03194, IPR004882): LUC7 N_terminus
Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
DDRGK (PF09756, IPR019153, SM01128): DDRGK domain
108 MDM2oncoprotein210.311352.049Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region
Presenilin (PF01080, IPR001108): Presenilin
SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain
zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
109 MED17oncoprotein40.5008.256Med17 (PF10156, IPR019313): Subunit 17 of Mediator complex
110 MED24interactor30.33327.951Med24_N (PF11277, IPR021429): Mediator complex subunit 24 N-terminal
111 METTL17interactor100Rsm22 (PF09243, IPR015324): Mitochondrial small ribosomal subunit Rsm22
112 MOV10interactor330.152968.698AAA_12 (PF13087): AAA domain
AAA_30 (PF13604): AAA domain
113 MPGinteractor50.50030.025Pur_DNA_glyco (PF02245, IPR003180): Methylpurine-DNA glycosylase (MPG)
114 MTFR2interactor100Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
115 NDC80protein found in more fusions140.269158.624DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
Ly49 (PF08391, IPR013600): Ly49-like protein, N-terminal region
Ndc80_HEC (PF03801, IPR005550): HEC/Ndc80p family
SlyX (PF04102, IPR007236): SlyX
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein
116 NDE1protein found in more fusions70.40012.912NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
117 NDNsuppressor60.50074.768MAGE (PF01454, IPR002190): MAGE family
118 NFIAinteractor100.37819.515CTF_NFI (PF00859, IPR000647): CTF/NF-I family transcription modulation region
NfI_DNAbd_pre-N (PF10524, IPR019548): Nuclear factor I protein pre-N-terminus
MH1 (PF03165, IPR003619, SM00523): MH1 domain
119 NFU1interactor100Nfu_N (PF08712, IPR014824, SM00932): Scaffold protein Nfu/NifU N terminal
NifU (PF01106, IPR001075): NifU-like domain
120 NTRK1oncoprotein580.2042430.812I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
121 NXF1interactor400.1521335.953NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding
TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
122 OIP5interactor21.0000Yippee-Mis18 (PF03226, IPR004910): Yippee zinc-binding/DNA-binding /Mis18, centromere assembly
123 PAXBP1interactor100.42220.636DUF1773 (PF08593, IPR013902): Domain of unknown function
GCFC (PF07842, IPR022783): GC-rich sequence DNA-binding factor-like protein
EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
124 PBX4interactor100PBC (PF03792, IPR005542): PBC domain
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
125 PDE4DIPoncoprotein140.121252.795ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
Med9 (PF07544, IPR011425): RNA polymerase II transcription mediator complex subunit 9
DivIC (PF04977, IPR007060): Septum formation initiator
DUF1220 (PF06758, IPR010630, SM01148): Repeat of unknown function (DUF1220)
DUF1515 (PF07439, IPR010889): Protein of unknown function (DUF1515)
IncA (PF04156, IPR007285): IncA protein
Cnn_1N (PF07989, IPR012943): Centrosomin N-terminal motif 1
Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
SlyX (PF04102, IPR007236): SlyX
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
DUF4140 (PF13600, IPR025554): N-terminal domain of unknown function (DUF4140)
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
Nup54 (PF13874, IPR025712): Nucleoporin complex subunit 54
FAM76 (PF16046, IPR032017): FAM76 protein
MPS2 (PF17060, IPR031433): Monopolar spindle protein 2
126 PHGDHinteractor150.49577.5522-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
127 PNKDinteractor2015.903Lactamase_B (PF00753, IPR001279, SM00849): Metallo-beta-lactamase superfamily
HAGH_C (PF16123, IPR032282): Hydroxyacylglutathione hydrolase C-terminus
128 POLLinteractor40.333158.956HHH (PF00633, IPR000445): Helix-hairpin-helix motif
DNA_pol_lambd_f (PF10391, IPR018944): Fingers domain of DNA polymerase lambda
HHH_5 (PF14520): Helix-hairpin-helix domain
HHH_8 (PF14716, IPR010996): Helix-hairpin-helix domain
DNA_pol_B_thumb (PF14791, IPR029398): DNA polymerase beta thumb
DNA_pol_B_palm (PF14792, IPR028207): DNA polymerase beta palm
BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
129 POMCinteractor21.0000ACTH_domain (PF00976, IPR013531): Corticotropin ACTH domain
NPP (PF08384, IPR013593): Pro-opiomelanocortin, N-terminal region
Op_neuropeptide (PF08035, IPR013532): Opioids neuropeptide
ACTH_assoc (PF16102, IPR032246): ACTH-associated domain
130 PPP1CAsuppressor150.257353.229Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
131 PPP1R16Ainteractor3014.916Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
132 PPP1R18interactor40.33330.478Totivirus_coat (PF05518, IPR008871): Totivirus coat protein
DUF4124 (PF13511, IPR025392): Domain of unknown function (DUF4124)
Phostensin (PF13914, IPR025907): Phostensin PP1-binding and SH3-binding region
Phostensin_N (PF13916, IPR025903): PP1-regulatory protein, Phostensin N-terminal
133 PRDX4protein found in more fusions80.28635.381AhpC-TSA (PF00578, IPR000866): AhpC/TSA family
1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin
134 PRKACAinteractor5093.447Pkinase (PF00069, IPR000719): Protein kinase domain
135 PRKCAinteractor80.38131.679C2 (PF00168, IPR000008, SM00239): C2 domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
136 PRPF19protein found in more fusions300.539111.530Prp19 (PF08606, IPR013915): Prp19/Pso4-like
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
U-box (PF04564, IPR003613, SM00504): U-box domain
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
137 PRPF3protein found in more fusions220.548247.717DUF1115 (PF06544, IPR010541): Protein of unknown function (DUF1115)
PRP3 (PF08572, IPR013881): pre-mRNA processing factor 3 (PRP3)
PWI (PF01480, IPR002483, SM00311): PWI domain
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
138 PRPF31interactor190.477219.289Nop (PF01798, IPR002687): snoRNA binding domain, fibrillarin
Cytokin_check_N (PF10407, IPR018844): Cdc14 phosphatase binding protein N-terminus
Prp31_C (PF09785, IPR019175): Prp31 C terminal domain
139 PRPF4interactor230.545250.789PRP4 (PF08799, IPR014906): pre-mRNA processing factor 4 (PRP4) like
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
WD40_like (PF17005, IPR031544): WD40-like domain
140 PRPF40Aprotein found in more fusions240.56568.634FF (PF01846, IPR002713, SM00441): FF domain
MCR_alpha (PF02249, IPR009047): Methyl-coenzyme M reductase alpha subunit, C-terminal domain
Transformer (PF06495, IPR010519): Fruit fly transformer protein
WW (PF00397, IPR001202, SM00456): WW domain
YqzE (PF14038, IPR025622): YqzE-like protein
SPT6_acidic (PF14632, IPR028083): Acidic N-terminal SPT6
SRRM_C (PF15230, IPR029360): Serine/arginine repetitive matrix protein C-terminus
SOBP (PF15279, IPR026092): Sine oculis-binding protein
IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
141 PRPF8oncoprotein320.473167.994PRO8NT (PF08082, IPR012591): PRO8NT (NUC069), PrP8 N-terminal domain
PROCN (PF08083, IPR012592): PROCN (NUC071) domain
PROCT (PF08084, IPR012984): PROCT (NUC072) domain
RRM_4 (PF10598, IPR019582): RNA recognition motif of the spliceosomal PrP8
U5_2-snRNA_bdg (PF10597, IPR019581): U5-snRNA binding site 2 of PrP8
U6-snRNA_bdg (PF10596, IPR019580): U6-snRNA interacting domain of PrP8
JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
PRP8_domainIV (PF12134, IPR021983): PRP8 domain IV core
142 PVRinteractor100C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain
CD34_antigen (PF06365, IPR013836): CD34/Podocalyxin family
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
143 RBM25interactor160.40865.104Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
PWI (PF01480, IPR002483, SM00311): PWI domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SMN (PF06003, IPR010304): Survival motor neuron protein (SMN)
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
DUF3441 (PF11923, IPR021846): Domain of unknown function (DUF3441)
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
DUF4778 (PF16008, IPR031958): Domain of unknown function (DUF4778)
144 RBM39oncoprotein280.413219.035RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
RBM39linker (PF15519, IPR029123): linker between RRM2 and RRM3 domains in RBM39 protein
145 RCOR3interactor50.50048.245ELM2 (PF01448, IPR000949): ELM2 domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
Myb_DNA-bind_7 (PF15963): Myb DNA-binding like
146 RHNO1interactor100RHINO (PF15319, IPR029293): RAD9, RAD1, HUS1-interacting nuclear orphan protein
147 RHOXF1interactor100Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
HTH_31 (PF13560): Helix-turn-helix domain
148 RPL13Ainteractor60.46746.562Ribosomal_L13 (PF00572, IPR005822): Ribosomal protein L13
149 RPS11interactor140.418100.215Ribosomal_S17 (PF00366, IPR000266): Ribosomal protein S17
Ribosomal_S17_N (PF16205, IPR032440): Ribosomal_S17 N-terminal
150 RRP7Ainteractor80.286209.026RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RRP7 (PF12923, IPR024326): Ribosomal RNA-processing protein 7 (RRP7)
151 RSRC1interactor80.50013.146DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755)
SOBP (PF15279, IPR026092): Sine oculis-binding protein
Ferlin_C (PF16165, IPR032362): Ferlin C-terminus
152 S100A9oncoprotein150.51628.775S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
153 S100Poncoprotein200S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
154 SAFBsuppressor110.47328.861RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SAP (PF02037, IPR003034, SM00513): SAP domain
Ferlin_C (PF16165, IPR032362): Ferlin C-terminus
155 SAP18interactor200.41663.589SAP18 (PF06487, IPR010516): Sin3 associated polypeptide p18 (SAP18)
156 SAP30BPinteractor80.50031.455Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein
HCNGP (PF07818, IPR012479): HCNGP-like protein
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
157 SART1interactor360.418721.784SART-1 (PF03343, IPR005011): SART-1 family
Dsh_C (PF12316, IPR024580): Segment polarity protein dishevelled (Dsh) C terminal
158 SEPT7interactor130.50022.077Fez1 (PF06818): Fez1
Septin (PF00735, IPR000038): Septin
159 SERPINE1interactor31.0000Serpin (PF00079, IPR023796, SM00093): Serpin (serine protease inhibitor)
160 SF3A1interactor270.610108.819TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
Surp (PF01805, IPR000061, SM00648): Surp module
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
PRP21_like_P (PF12230, IPR022030): Pre-mRNA splicing factor PRP21 like protein
161 SF3B1oncoprotein290.58667.699Dopey_N (PF04118, IPR007249): Dopey, N-terminal
HEAT (PF02985, IPR000357): HEAT repeat
SF3b1 (PF08920, IPR015016): Splicing factor 3B subunit 1
UNC45-central (PF11701, IPR024660): Myosin-binding striated muscle assembly central
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
162 SF3B3interactor290.55495.561CPSF_A (PF03178, IPR004871): CPSF A subunit region
MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term
163 SF3B6interactor200.53263.486RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
164 SFPQoncoprotein210.62644.085GRP (PF07172, IPR010800): Glycine rich protein family
Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
NOPS (PF08075, IPR012975): NOPS (NUC059) domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
PAT1 (PF09770, IPR019167): Topoisomerase II-associated protein PAT1
CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
165 SFR1interactor30.6677.622Mei5 (PF10376, IPR018468): Double-strand recombination repair protein
166 SH2D4Ainteractor30.6671.234Cytochrom_NNT (PF03264, IPR005126): NapC/NirT cytochrome c family, N-terminal region
Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal
SH2 (PF00017, IPR000980, SM00252): SH2 domain
DUF2039 (PF10217, IPR019351): Uncharacterized conserved protein (DUF2039)
167 SH3GLB1suppressor50.16762.112BAR (PF03114, IPR004148, SM00721): BAR domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
168 SIX1oncoprotein100KilA-N (PF04383, IPR018004): KilA-N domain
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
SIX1_SD (PF16878, IPR031701): Transcriptional regulator, SIX1, N-terminal SD domain
169 SMARCB1suppressor80.33368.876SNF5 (PF04855, IPR006939): SNF5 / SMARCB1 / INI1
170 SMARCE1interactor70.33372.086DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
GCN5L1 (PF06320, IPR009395): GCN5-like protein 1 (GCN5L1)
Ndc1_Nup (PF09531, IPR019049): Nucleoporin protein Ndc1-Nup
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
Ferlin_C (PF16165, IPR032362): Ferlin C-terminus
171 SMU1interactor150.53317.695LisH (PF08513, IPR013720, SM00667): LisH
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
172 SNRNP40interactor180.477149.353WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
173 SNRNP70interactor190.526267.957RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
174 SNRPA1interactor260.517160.672LRR_9 (PF14580): Leucine-rich repeat
175 SNRPBinteractor50.30056.173LSM (PF01423, IPR001163): LSM domain
176 SNU13interactor210.35878.546Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
177 SNW1protein found in more fusions460.3171078.281SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
SIR4_SID (PF16991, IPR031556): Sir4 SID domain
178 SNX20interactor100PX (PF00787, IPR001683, SM00312): PX domain
TPR_12 (PF13424): Tetratricopeptide repeat
179 SRSF1protein found in more fusions360.462259.202Corona_nucleoca (PF00937, IPR001218): Coronavirus nucleocapsid protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
180 SRSF10interactor140.46228.023RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
181 SRSF11interactor230.379132.722Rtf2 (PF04641, IPR027799): Rtf2 RING-finger
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TP2 (PF01254, IPR000678): Nuclear transition protein 2
Transformer (PF06495, IPR010519): Fruit fly transformer protein
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
182 SSX2IPprotein found in more fusions190.157279.581ZapB (PF06005, IPR009252): Cell division protein ZapB
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
Surfac_D-trimer (PF09006, IPR015097): Lung surfactant protein D coiled-coil trimerisation
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
YqzH (PF14164, IPR025546): YqzH-like protein
183 STRNoncoprotein30.66713.686CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
Nucleoporin_N (PF08801, IPR014908): Nup133 N terminal like
Striatin (PF08232, IPR013258): Striatin family
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
184 TCAF1interactor21.0000Peptidase_M60 (PF13402, IPR031161): Peptidase M60, enhancin and enhancin-like
185 TERF2interactor110.222117.188Aconitase_C (PF00694, IPR000573): Aconitase C-terminal domain
TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF)
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
TERF2_RBM (PF16772, IPR031902): Telomeric repeat-binding factor 2 Rap1-binding motif
186 TFPToncoprotein40.33323.241GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor
187 TGFB1suppressor21.0000TGFb_propeptide (PF00688, IPR001111): TGF-beta propeptide
TGF_beta (PF00019, IPR001839, SM00204): Transforming growth factor beta like domain
188 TGFB2oncoprotein21.0000TGFb_propeptide (PF00688, IPR001111): TGF-beta propeptide
TGF_beta (PF00019, IPR001839, SM00204): Transforming growth factor beta like domain
189 THAP7protein found in more fusions4087.464THAP (PF05485, IPR006612, SM00980): THAP domain
Tho2 (PF11262, IPR021418): Transcription factor/nuclear export subunit protein 2
190 THAP8interactor21.0000THAP (PF05485, IPR006612, SM00980): THAP domain
DUF4124 (PF13511, IPR025392): Domain of unknown function (DUF4124)
191 TNNT1protein found in more fusions40.66716.172Troponin (PF00992, IPR001978): Troponin
DUF4050 (PF13259, IPR025124): Protein of unknown function (DUF4050)
192 TP53suppressor310.186972.229DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
193 TRAF3IP3interactor21.0000ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
FUSC (PF04632, IPR006726): Fusaric acid resistance protein family
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
194 TRAPPC4interactor3015.903Sybindin (PF04099, IPR007233): Sybindin-like family
195 TSHZ3interactor100LMP (PF04778, IPR006864): LMP repeated region
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
zf-met (PF12874): Zinc-finger of C2H2 type
zf-C2HE (PF16278, IPR032566): C2HE / C2H2 / C2HC zinc-binding finger
196 TSPYL4interactor100Lipoprotein_7 (PF01540, IPR002520): Adhesin lipoprotein
NAP (PF00956, IPR002164): Nucleosome assembly protein (NAP)
AXIN1_TNKS_BD (PF16646, IPR032101): Axin-1 tankyrase binding domain
197 TSSC4suppressor100.400125.061TSSC4 (PF15264, IPR029338): Tumour suppressing sub-chromosomal transferable candidate 4
198 TUFT1interactor100USP8_interact (PF08941, IPR015036): USP8 interacting
Hrs_helical (PF12210, IPR024641): Hepatocyte growth factor-regulated tyrosine kinase substrate
2_5_RNA_ligase2 (PF13563): 2'-5' RNA ligase superfamily
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
199 TXLNAprotein found in more fusions130.303191.730Taxilin (PF09728, IPR026183): Myosin-like coiled-coil protein
KELK (PF15796, IPR031597): KELK-motif containing domain of MRCK Ser/Thr protein kinase
200 USP39oncoprotein230.502110.139UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
201 USP7oncoprotein140.359148.473MATH (PF00917, IPR002083, SM00061): MATH domain
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
USP7_ICP0_bdg (PF12436, IPR024729): ICP0-binding domain of Ubiquitin-specific protease 7
USP7_C2 (PF14533, IPR029346): Ubiquitin-specific protease C-terminal
202 VEGFAsuppressor31.0000PDGF (PF00341, IPR000072, SM00141): PDGF/VEGF domain
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
VEGF_C (PF14554, IPR027928): VEGF heparin-binding domain
203 VPS37Cinteractor2015.903Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein
204 WDR18interactor130.56425.618WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
WD40_alt (PF14077, IPR026987): Alternative WD40 repeat motif
205 ZC2HC1Cinteractor21.0000zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
zf-C2HC_2 (PF13913): zinc-finger of a C2HC-type
206 ZFYVE26oncoprotein21.0000FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
MerR-DNA-bind (PF09278, IPR015358): MerR, DNA binding
FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_14 (PF13428): Tetratricopeptide repeat
207 ZGPATinteractor70.28644.347Agenet (PF05641, IPR008395, SM00743): Agenet domain
G-patch (PF01585, IPR000467, SM00443): G-patch domain
Laminin_I (PF06008, IPR009254): Laminin Domain I
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167
208 ZMAT2interactor21.0000Cgr1 (PF03879, IPR005579): Cgr1 family
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
209 ZNF417interactor31.0000A2L_zn_ribbon (PF08792, IPR014900): A2L zinc ribbon domain
C1_4 (PF07975, IPR004595, SM01047): TFIIH C1-like domain
KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
210 ZSCAN12interactor31.0000Zn-ribbon_8 (PF09723, IPR013429, SM00834): Zinc ribbon domain
SCAN (PF02023, IPR003309, SM00431): SCAN domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain

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