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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)193
The number (and %) of the onco-proteins63 (32.64 %)
The number (and %) of the tumor suppressors29 (15.03 %)
Total number of binary PPIs (saturation %)1216 (6.56 %)
The number (and %) of affected PPIs195 (16.04 %)
The number of possible different fusions47
PPI diameter4
PPI radius2
The average degree of PPI11.513
Assortativity coefficient-0.3161
The network average Clustering coefficient0.479
The number (and %) of a zero Clustering coefficients16 (8.29 %)
The number (and %) of a zero Betweenness Centrality41 (21.24 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: UBE2N,BRAF All fusions
Proteins found in more fusions TRIM25 (see 2 fusions); GNPNAT1 (see 1 fusions); MAPK1 (see 2 fusions); RNF168 (see 2 fusions); UBE2N (see 1 fusions); PARK2 (see 1 fusions); UBA1 (see 2 fusions); YWHAH (see 2 fusions); KSR1 (see 1 fusions); ARIH2 (see 2 fusions); CCDC88A (see 3 fusions); SH3RF1 (see 1 fusions); AURKA (see 1 fusions); YWHAZ (see 5 fusions); MYLIP (see 1 fusions); PJA2 (see 1 fusions); FN1/YWHAG (see 1 fusions); PAK2 (see 3 fusions); UBC (see 7 fusions); DZIP3 (see 1 fusions); LIMK1 (see 1 fusions); TP53 (see 3 fusions); SNW1 (see 1 fusions); ARIH1 (see 4 fusions); TRAF6 (see 1 fusions); RNF11 (see 1 fusions); TNF (see 1 fusions); YWHAG (see 1 fusions); HSP90AA1 (see 6 fusions); TRIM28 (see 1 fusions); TRIM33 (see 1 fusions); SFN (see 1 fusions); HSP90AB1 (see 3 fusions); ZNRF1 (see 1 fusions); NEDD4L (see 4 fusions); MALT1 (see 1 fusions); RNF111 (see 1 fusions); SF1 (see 1 fusions); BAG3 (see 4 fusions); RIPK1 (see 1 fusions); BRAF (see 3 fusions); HSPB1 (see 1 fusions); CDC37 (see 2 fusions); PRKCE (see 3 fusions); MFN2 (see 2 fusions); MIB1 (see 4 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 UBE2Nparental protein1530.04320563.133UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
2 BRAFparental protein420.2111323.817Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
RBD (PF02196, IPR003116, SM00455): Raf-like Ras-binding domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
3 ACACAinteractor40.5000.765ACC_central (PF08326, IPR013537): Acetyl-CoA carboxylase, central region
Biotin_carb_C (PF02785, IPR005482, SM00878): Biotin carboxylase C-terminal domain
Biotin_lipoyl (PF00364, IPR000089): Biotin-requiring enzyme
Carboxyl_trans (PF01039, IPR000022): Carboxyl transferase domain
Biotin_carb_N (PF00289, IPR005481): Biotin carboxylase, N-terminal domain
CPSase_L_D2 (PF02786, IPR005479): Carbamoyl-phosphate synthase L chain, ATP binding domain
DUF445 (PF04286, IPR007383): Protein of unknown function (DUF445)
4 ACOT13interactor40.6670.1184HBT (PF03061, IPR006683): Thioesterase superfamily
DUF4442 (PF14539, IPR027961): Domain of unknown function (DUF4442)
5 ACTR2interactor90.47246.085Actin (PF00022, IPR004000, SM00268): Actin
6 AKT1oncoprotein280.251319.345PH (PF00169, IPR001849, SM00233): PH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
7 AMFRoncoprotein100.36126.044CUE (PF02845, IPR003892, SM00546): CUE domain
UbiA (PF01040, IPR000537): UbiA prenyltransferase family
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
8 ARAFoncoprotein170.41270.801Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
RBD (PF02196, IPR003116, SM00455): Raf-like Ras-binding domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
9 ARF4interactor80.39322.386Arf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family
10 ARIH1protein found in more fusions40.6670.167CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
Med14 (PF08638, IPR013947): Mediator complex subunit MED14
zinc_ribbon_2 (PF13240, IPR026870): zinc-ribbon domain
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain
11 ARIH2protein found in more fusions70.8001.132IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
zinc_ribbon_12 (PF11331, IPR021480): Probable zinc-ribbon domain
zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
PRAS (PF15798, IPR026682): Proline-rich AKT1 substrate 1
12 ASPDHinteractor21.0000DUF108 (PF01958, IPR002811): Domain of unknown function DUF108
NAD_binding_3 (PF03447, IPR005106): Homoserine dehydrogenase, NAD binding domain
13 ATP2B3interactor21.0000Cation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus
Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus
E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
ATP_Ca_trans_C (PF12424, IPR022141): Plasma membrane calcium transporter ATPase C terminal
Cation_ATPase (PF13246): Cation transport ATPase (P-type)
14 ATP6V1Hinteractor100V-ATPase_H_N (PF03224, IPR004908): V-ATPase subunit H
V-ATPase_H_C (PF11698, IPR011987): V-ATPase subunit H
15 AURKAoncoprotein210.363156.861Pkinase (PF00069, IPR000719): Protein kinase domain
MTBP_C (PF14920, IPR029418): MDM2-binding
16 BADoncoprotein130.66713.770Bcl-2_BAD (PF10514, IPR018868): Pro-apoptotic Bcl-2 protein, BAD
17 BAG3oncoprotein180.434106.795BAG (PF02179, IPR003103, SM00264): BAG domain
WW (PF00397, IPR001202, SM00456): WW domain
18 BARD1suppressor130.348145.860BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
zf-RING_6 (PF14835): zf-RING of BARD1-type protein
BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
19 BCL10suppressor150.35280.612CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain
20 BFARinteractor31.0000SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
DUF2231 (PF09990, IPR019251): Predicted membrane protein (DUF2231)
zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
21 BIRC3oncoprotein160.42975.828BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain
CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
22 BIRC8interactor40.8330.397BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
23 BRAPinteractor80.47648.751BRAP2 (PF07576, IPR011422): BRCA1-associated protein 2
DUF87 (PF01935, IPR002789): Domain of unknown function DUF87
zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
KASH_CCD (PF14662, IPR028168): Coiled-coil region of CCDC155 or KASH
24 BRCA1suppressor250.199408.606BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT
25 CAB39interactor40.5003.000Mo25 (PF08569, IPR013878): Mo25-like
26 CADPS2oncoprotein100DUF1041 (PF06292, IPR010439, SM01145): Domain of Unknown Function (DUF1041)
PH (PF00169, IPR001849, SM00233): PH domain
27 CCDC88Aprotein found in more fusions70.3339.070bZIP_1 (PF00170, IPR004827): bZIP transcription factor
ZapB (PF06005, IPR009252): Cell division protein ZapB
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
HOOK (PF05622, IPR008636): HOOK protein
Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein
BLOC1_2 (PF10046, IPR019269): Biogenesis of lysosome-related organelles complex-1 subunit 2
KxDL (PF10241, IPR019371): Uncharacterized conserved protein
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472)
TolA_bind_tri (PF16331, IPR032519): TolA binding protein trimerisation
APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain
28 CDC37protein found in more fusions190.45184.601CDC37_C (PF08564, IPR013873, SM01069): Cdc37 C terminal domain
CDC37_M (PF08565, IPR013874, SM01070): Cdc37 Hsp90 binding domain
CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding
Rho_Binding (PF08912, IPR015008): Rho Binding
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
29 CDC5Linteractor220.314176.600OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component
Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
30 CDK2suppressor260.260274.301Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
31 CHFRsuppressor50.5001.945FHA (PF00498, IPR000253, SM00240): FHA domain
Glyco_hydro_92 (PF07971, IPR012939): Glycosyl hydrolase family 92
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
LAX (PF15681, IPR031393): Lymphocyte activation family X
32 CHUKsuppressor170.43375.440Pkinase (PF00069, IPR000719): Protein kinase domain
IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain
33 CNEP1R1interactor21.0000Tmemb_18A (PF09771, IPR019168): Transmembrane protein 188
34 CNOT4interactor31.0000RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain
Nup35_RRM_2 (PF14605): Nup53/35/40-type RNA recognition motif
zf-CCCH_2 (PF14608): RNA-binding, Nab2-type zinc finger
35 DTLinteractor120.43983.858WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
36 DTX1interactor200WWE (PF02825, IPR004170, SM00678): WWE domain
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
zf-UDP (PF14569, IPR027934): Zinc-binding RING-finger
PRIMA1 (PF16101): Proline-rich membrane anchor 1
37 DZIP3protein found in more fusions60.7000.806DUF16 (PF01519, IPR002862): Protein of unknown function DUF16
SlyX (PF04102, IPR007236): SlyX
zf-RING-like (PF08746, IPR014857): RING-like domain
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
PKcGMP_CC (PF16808, IPR031831): Coiled-coil N-terminus of cGMP-dependent protein kinase
38 ELAVL1oncoprotein490.0792020.524RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
39 EPM2Ainteractor60.6003.232CBM_20 (PF00686, IPR002044): Starch binding domain
DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
40 F12interactor200EGF (PF00008, IPR000742, SM00181): EGF-like domain
fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
Kringle (PF00051, IPR000001): Kringle domain
Trypsin (PF00089, IPR001254, SM00020): Trypsin
41 FBXW7suppressor110.15665.531Mem_trans (PF03547, IPR004776): Membrane transport protein
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
F-box-like (PF12937, IPR001810): F-box-like
42 FHsuppressor60.46714.687Lyase_1 (PF00206, IPR022761): Lyase
FumaraseC_C (PF10415, IPR018951): Fumarase C C-terminus
43 FN1oncoprotein280.249332.473fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
44 GNPNAT1protein found in more fusions40.6671.000Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family
45 HADHinteractor30.33324.4543HCDH (PF00725, IPR006108): 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain
3HCDH_N (PF02737, IPR006176): 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
Pyr_redox_2 (PF07992, IPR023753): Pyridine nucleotide-disulphide oxidoreductase
46 HERC2interactor140.192316.250ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
Cyt-b5 (PF00173, IPR001199, SM01117): Cytochrome b5-like Heme/Steroid binding domain
MIB_HERC2 (PF06701, IPR010606): Mib_herc2
RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat
zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box)
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal
RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
47 HLTFsuppressor120.36444.328HIRAN (PF08797, IPR014905, SM00910): HIRAN domain
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
48 HNRNPA3oncoprotein90.61116.817IATP (PF04568, IPR007648): Mitochondrial ATPase inhibitor, IATP
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
49 HRASoncoprotein70.28626.728Ras (PF00071, IPR001806, SM00173): Ras family
50 HSP90AA1oncoprotein460.1961301.230HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
51 HSP90AB1oncoprotein300.379189.864HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
52 HSPA1Ainteractor210.386145.289HSP70 (PF00012, IPR013126): Hsp70 protein
53 HSPA5oncoprotein280.356222.854HSP70 (PF00012, IPR013126): Hsp70 protein
54 HSPA8oncoprotein330.347257.847HSP70 (PF00012, IPR013126): Hsp70 protein
55 HSPA9oncoprotein150.39040.933HSP70 (PF00012, IPR013126): Hsp70 protein
56 HSPB1oncoprotein300.328334.444HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
57 IDH3Ainteractor2014.337Iso_dh (PF00180, IPR024084): Isocitrate/isopropylmalate dehydrogenase
58 IL1Boncoprotein21.0000IL1 (PF00340, IPR000975, SM00125): Interleukin-1 / 18
IL1_propep (PF02394, IPR003502): Interleukin-1 propeptide
59 IQGAP1interactor200.253181.675CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
DUF87 (PF01935, IPR002789): Domain of unknown function DUF87
IDEAL (PF08858, IPR014957, SM00914): IDEAL domain
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase
RasGAP_C (PF03836, IPR000593): RasGAP C-terminus
WW (PF00397, IPR001202, SM00456): WW domain
60 ISG15suppressor130.35969.161ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
61 KIF1Cinteractor70.57128.504FHA (PF00498, IPR000253, SM00240): FHA domain
IncA (PF04156, IPR007285): IncA protein
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
Kinesin_assoc (PF16183, IPR032405): Kinesin-associated
62 KSR1oncoprotein80.7146.545Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
KSR1-SAM (PF13543, IPR025561): SAM like domain present in kinase suppressor RAS 1
63 LDHAL6Ainteractor31.0000Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain
Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain
64 LDHBinteractor170.342152.922Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain
Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain
65 LDHCinteractor30.6671.287Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain
Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain
66 LGALS1interactor60.26756.853Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin
67 LIMK1oncoprotein70.40021.541LIM (PF00412, IPR001781, SM00132): LIM domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
68 LIPFinteractor205.370Abhydro_lipase (PF04083, IPR006693): Partial alpha/beta-hydrolase lipase region
Abhydrolase_1 (PF00561, IPR000073): alpha/beta hydrolase fold
69 LRSAM1interactor90.357247.682Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
70 MALT1oncoprotein90.6793.260Peptidase_C14 (PF00656, IPR011600): Caspase domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
71 MAP2K1oncoprotein170.38398.097Pkinase (PF00069, IPR000719): Protein kinase domain
DUF3216 (PF11505, IPR023108): Protein of unknown function (DUF3216)
72 MAP2K2interactor110.46727.421Pkinase (PF00069, IPR000719): Protein kinase domain
CAMSAP_CC1 (PF17095, IPR031372): Spectrin-binding region of Ca2+-Calmodulin
73 MAPK1oncoprotein130.34868.917Pkinase (PF00069, IPR000719): Protein kinase domain
74 MAPK3oncoprotein140.256119.008Pkinase (PF00069, IPR000719): Protein kinase domain
75 MARCH5interactor50.6671.914DUF2517 (PF10725, IPR019663): Protein of unknown function (DUF2517)
RINGv (PF12906, IPR011016, SM00744): RING-variant domain
76 MARCH7interactor51.0000RINGv (PF12906, IPR011016, SM00744): RING-variant domain
77 MDM2oncoprotein240.257208.166Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region
Presenilin (PF01080, IPR001108): Presenilin
SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain
zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
78 MFN2protein found in more fusions41.0000Apolipoprotein (PF01442, IPR000074): Apolipoprotein A1/A4/E domain
Fzo_mitofusin (PF04799, IPR006884): fzo-like conserved region
Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family
79 MIB1protein found in more fusions31.0000Ank (PF00023, IPR002110, SM00248): Ankyrin repeat
MIB_HERC2 (PF06701, IPR010606): Mib_herc2
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
80 MIB2oncoprotein21.0000Ank (PF00023, IPR002110, SM00248): Ankyrin repeat
KOW (PF00467, IPR005824, SM00739): KOW motif
MIB_HERC2 (PF06701, IPR010606): Mib_herc2
TPR_4 (PF07721, IPR011717): Tetratricopeptide repeat
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
81 MID1oncoprotein90.42918.229Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
82 MID2interactor70.5333.788fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
CEBP_ZZ (PF16366, IPR032296): Cytoplasmic polyadenylation element-binding protein ZZ domain
APC_u15 (PF16636): Unstructured region on APC between APC_crr regions 5 and 6
83 MKRN3oncoprotein100.44431.193zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
MKRN1_C (PF15815, IPR031644): E3 ubiquitin-protein ligase makorin-1, C-terminal
Torus (PF16131, IPR032297): Torus domain
zf-3CxxC_2 (PF17180): Zinc-binding domain
84 MRASoncoprotein21.0000Ras (PF00071, IPR001806, SM00173): Ras family
85 MUS81suppressor50.10014.704ERCC4 (PF02732, IPR006166, SM00891): ERCC4 domain
MutL (PF13941, IPR006230): MutL protein
HHH_8 (PF14716, IPR010996): Helix-hairpin-helix domain
86 MYLIPprotein found in more fusions200FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
87 NBNsuppressor80.39325.946FHA (PF00498, IPR000253, SM00240): FHA domain
Nbs1_C (PF08599, IPR013908): DNA damage repair protein Nbs1
NIBRIN_BRCT_II (PF16508, IPR032429): Second BRCT domain on Nijmegen syndrome breakage protein
RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
88 NEDD4Lsuppressor150.462212.079WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
89 NEURL1suppressor21.0000Neuralized (PF07177, IPR006573, SM00588): Neuralized
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
90 NFX1interactor207.436R3H (PF01424, IPR001374, SM00393): R3H domain
XPG_I (PF00867, IPR006086, SM00484): XPG I-region
zf-NF-X1 (PF01422, IPR000967, SM00438): NF-X1 type zinc finger
91 NHLRC1interactor50.8332.117NHL (PF01436, IPR001258): NHL repeat
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
92 OTUB1interactor180.294166.189Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain
93 OTUB2interactor120.36430.111Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain
94 PAK2protein found in more fusions120.50925.248PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain
Pkinase (PF00069, IPR000719): Protein kinase domain
95 PARK2suppressor290.198597.805IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
96 PCinteractor100Biotin_carb_C (PF02785, IPR005482, SM00878): Biotin carboxylase C-terminal domain
Biotin_lipoyl (PF00364, IPR000089): Biotin-requiring enzyme
Biotin_carb_N (PF00289, IPR005481): Biotin carboxylase, N-terminal domain
CPSase_L_D2 (PF02786, IPR005479): Carbamoyl-phosphate synthase L chain, ATP binding domain
HMGL-like (PF00682, IPR000891): HMGL-like
PYC_OADA (PF02436, IPR003379): Conserved carboxylase domain
97 PCCAinteractor31.0000Biotin_carb_C (PF02785, IPR005482, SM00878): Biotin carboxylase C-terminal domain
Biotin_lipoyl (PF00364, IPR000089): Biotin-requiring enzyme
Biotin_carb_N (PF00289, IPR005481): Biotin carboxylase, N-terminal domain
CPSase_L_D2 (PF02786, IPR005479): Carbamoyl-phosphate synthase L chain, ATP binding domain
SLT_beta (PF02258, IPR003189): Shiga-like toxin beta subunit
98 PCCBinteractor31.0000Carboxyl_trans (PF01039, IPR000022): Carboxyl transferase domain
99 PELI1interactor50.8000.592Pellino (PF04710, IPR006800): Pellino
100 PELI3interactor41.0000Pellino (PF04710, IPR006800): Pellino
101 PHGDHinteractor120.28847.7792-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
102 PHKBinteractor30.3333.783Glyco_hydro_15 (PF00723, IPR011613): Glycosyl hydrolases family 15
103 PJA2protein found in more fusions31.0000zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding
Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
104 PPIAinteractor90.38921.434Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
105 PRKCEsuppressor100.41730.360C2 (PF00168, IPR000008, SM00239): C2 domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
106 RAD23Aoncoprotein160.33371.581UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
XPC-binding (PF09280, IPR015360): XPC-binding domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
107 RAD23Bsuppressor110.43618.004K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
XPC-binding (PF09280, IPR015360): XPC-binding domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
DUF3123 (PF11321, IPR021470): Protein of unknown function (DUF3123)
108 RAF1oncoprotein300.264496.670Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
RBD (PF02196, IPR003116, SM00455): Raf-like Ras-binding domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
109 RAP1Asuppressor50.30082.516Ras (PF00071, IPR001806, SM00173): Ras family
110 RAP1GAPsuppressor21.0000GoLoco (PF02188, IPR003109, SM00390): GoLoco motif
Rap_GAP (PF02145, IPR000331): Rap/ran-GAP
111 RBCK1interactor150.40741.870GAGA (PF09237, IPR015318): GAGA factor
IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
112 RC3H1interactor40.6671.018PaaA_PaaC (PF05138, IPR007814): Phenylacetic acid catabolic protein
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
113 RC3H2interactor70.6673.097Xin (PF08043, IPR012510): Xin repeat
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
114 RFWD3interactor60.60022.476OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
115 RHNO1interactor21.0000RHINO (PF15319, IPR029293): RAD9, RAD1, HUS1-interacting nuclear orphan protein
116 RIPK1protein found in more fusions140.48725.504Death (PF00531, IPR000488, SM00005): Death domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
RHIM (PF12721, IPR025735): RIP homotypic interaction motif
117 RNF103interactor100VWC (PF00093, IPR001007, SM00214): von Willebrand factor type C domain
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
118 RNF11protein found in more fusions110.35635.441zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
zf-ANAPC11 (PF12861, IPR024991): Anaphase-promoting complex subunit 11 RING-H2 finger
119 RNF111suppressor80.6198.677zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
Prok-RING_1 (PF14446): Prokaryotic RING finger family 1
RNF111_N (PF15303, IPR029306): E3 ubiquitin-protein ligase Arkadia N-terminus
120 RNF115interactor100.25093.750Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
zinc_ribbon_9 (PF14369): zinc-ribbon
121 RNF122interactor31.0000zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
Prok-RING_1 (PF14446): Prokaryotic RING finger family 1
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
122 RNF125interactor60.7004.647zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding
Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
123 RNF126interactor70.5337.053Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
zinc_ribbon_9 (PF14369): zinc-ribbon
124 RNF128interactor41.0000CcmD (PF04995, IPR007078): Heme exporter protein D (CcmD)
PA (PF02225, IPR003137): PA domain
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
125 RNF13interactor100DNA_ligase_ZBD (PF03119, IPR004149): NAD-dependent DNA ligase C4 zinc finger domain
PA (PF02225, IPR003137): PA domain
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
FAM176 (PF14851): FAM176 family
STAC2_u1 (PF16664): Unstructured on SH3 and cysteine-rich domain-containing protein 2
126 RNF130interactor30.6670.231PA (PF02225, IPR003137): PA domain
PspB (PF06667, IPR009554): Phage shock protein B
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
Prok-RING_1 (PF14446): Prokaryotic RING finger family 1
127 RNF149interactor203.277PA (PF02225, IPR003137): PA domain
UPF0233 (PF06781, IPR009619): Uncharacterised protein family (UPF0233)
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
Zn_ribbon_17 (PF17120): Zinc-ribbon, C4HC2 type
128 RNF152interactor100VMA21 (PF09446, IPR019013): VMA21-like domain
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
129 RNF165interactor21.0000zf-P11 (PF03854, IPR003224): P-11 zinc finger
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
130 RNF167interactor31.0000DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
PA (PF02225, IPR003137): PA domain
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
Glucos_trans_II (PF14264, IPR025686): Glucosyl transferase GtrII
Prok-RING_1 (PF14446): Prokaryotic RING finger family 1
131 RNF168protein found in more fusions60.6002.707ATP-synt_E (PF05680, IPR008386): ATP synthase E chain
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
132 RNF181interactor50.6670.740AhpC-TSA (PF00578, IPR000866): AhpC/TSA family
133 RNF182interactor30.6670.200zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
134 RNF4interactor50.8330.368Sgf11 (PF08209, IPR013246): Sgf11 (transcriptional regulation protein)
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
zf-UDP (PF14569, IPR027934): Zinc-binding RING-finger
135 RNF43oncoprotein31.0000IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
136 RNF5interactor70.7331.564zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
137 RNF8suppressor100.41715.028FHA (PF00498, IPR000253, SM00240): FHA domain
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
DUF4665 (PF15679, IPR031389): Domain of unknown function (DUF4665)
138 RPS6KB2interactor150.42941.226Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
139 SARDHinteractor100DAO (PF01266, IPR006076): FAD dependent oxidoreductase
GCV_T (PF01571, IPR006222): Aminomethyltransferase folate-binding domain
GCV_T_C (PF08669, IPR013977): Glycine cleavage T-protein C-terminal barrel domain
FAO_M (PF16350, IPR032503): FAD dependent oxidoreductase central domain
140 SF1protein found in more fusions70.33314.849UPF0181 (PF03701, IPR005371): Uncharacterised protein family (UPF0181)
zf-CCHC (PF00098, IPR001878): Zinc knuckle
KH_1 (PF00013, IPR004088, SM00322): KH domain
RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein
PRIMA1 (PF16101): Proline-rich membrane anchor 1
SF1-HH (PF16275, IPR032570): Splicing factor 1 helix-hairpin domain
141 SFNsuppressor220.300175.23814-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
142 SH3RF1protein found in more fusions60.20027.279zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
143 SH3RF2interactor40.5002.758SH3_2 (PF07653, IPR011511): Variant SH3 domain
TUDOR (PF00567, IPR002999, SM00333): Tudor domain
UPF0547 (PF10571, IPR018886): Uncharacterised protein family UPF0547
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
SH3_9 (PF14604, IPR001452): Variant SH3 domain
144 SHPRHsuppressor50.50023.673SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
GIT1_C (PF12205, IPR022018): G protein-coupled receptor kinase-interacting protein 1 C term
TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
145 SIAH1suppressor80.4298.012Sina (PF03145, IPR018121): Seven in absentia protein family
146 SLC2A4interactor21.0000Sugar_tr (PF00083, IPR005828): Sugar (and other) transporter
147 SNW1protein found in more fusions210.300250.101SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
SIR4_SID (PF16991, IPR031556): Sir4 SID domain
148 STAMBPL1interactor50.50021.831CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain
USP8_dimer (PF08969, IPR015063): USP8 dimerisation domain
JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
149 STUB1suppressor300.315453.688U-box (PF04564, IPR003613, SM00504): U-box domain
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_20 (PF14561): Tetratricopeptide repeat
150 TERF1interactor130.27393.443TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF)
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
151 TMEM189interactor50.40032.334MARVEL (PF01284, IPR008253): Membrane-associating domain
TMEM189_B_dmain (PF10520, IPR019547): B domain of TMEM189, localisation domain
152 TMEM189-UBE2V1interactor30.6670.878MARVEL (PF01284, IPR008253): Membrane-associating domain
UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
TMEM189_B_dmain (PF10520, IPR019547): B domain of TMEM189, localisation domain
153 TNFoncoprotein140.385128.356TNF (PF00229, IPR006052, SM00207): TNF(Tumour Necrosis Factor) family
154 TNFAIP3suppressor230.338187.711OTU (PF02338, IPR003323): OTU-like cysteine protease
zf-A20 (PF01754, IPR002653, SM00259): A20-like zinc finger
Thioredoxin_3 (PF13192, IPR012336): Thioredoxin domain
155 TOPORSsuppressor50.7003.956Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif
Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
156 TP53suppressor450.1901208.863DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
157 TRAF2interactor190.47748.086MATH (PF00917, IPR002083, SM00061): MATH domain
Sina (PF03145, IPR018121): Seven in absentia protein family
SlyX (PF04102, IPR007236): SlyX
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger
TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain
zf-C3HC4_5 (PF17121, IPR001841): Zinc finger, C3HC4 type (RING finger)
158 TRAF6protein found in more fusions220.319185.403SlyX (PF04102, IPR007236): SlyX
zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
159 TRIM11interactor40.6670.400ATP-synt_B (PF00430, IPR002146): ATP synthase B/B' CF(0)
SPRY (PF00622, IPR003877, SM00449): SPRY domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
160 TRIM17interactor60.5337.368NlpE (PF04170, IPR007298): NlpE N-terminal domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
zf-Nse (PF11789, IPR004181): Zinc-finger of the MIZ type in Nse subunit
zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
161 TRIM25protein found in more fusions110.26767.735Fes1 (PF08609, IPR013918): Nucleotide exchange factor Fes1
Pox_Rif (PF03340, IPR005008): Poxvirus rifampicin resistance protein
SPRY (PF00622, IPR003877, SM00449): SPRY domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
162 TRIM27oncoprotein150.34164.735IncA (PF04156, IPR007285): IncA protein
SPRY (PF00622, IPR003877, SM00449): SPRY domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease
163 TRIM28protein found in more fusions150.33086.700ASFV_J13L (PF05568, IPR008385): African swine fever virus J13L protein
K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
PHD (PF00628, IPR019787, SM00249): PHD-finger
FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2
164 TRIM32suppressor200.327197.702NHL (PF01436, IPR001258): NHL repeat
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
Zn_Tnp_IS1595 (PF12760, IPR024442): Transposase zinc-ribbon domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
165 TRIM33oncoprotein31.0000PHD (PF00628, IPR019787, SM00249): PHD-finger
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
Siva (PF05458, IPR022773): Cd27 binding protein (Siva)
Spectrin (PF00435, IPR002017): Spectrin repeat
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
166 TRIM39interactor80.6195.689Exonuc_VII_L (PF02601, IPR020579): Exonuclease VII, large subunit
Prim_Zn_Ribbon (PF08273, IPR013237, SM00778): Zinc-binding domain of primase-helicase
SPRY (PF00622, IPR003877, SM00449): SPRY domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
167 TRIM5interactor100.5837.143Baculo_IE-1 (PF05290, IPR007954): Baculovirus immediate-early protein (IE-0)
Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus
SPRY (PF00622, IPR003877, SM00449): SPRY domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
168 TRIM50interactor100Trimer_CC (PF08954, IPR015049, SM01167): Trimerisation motif
SPRY (PF00622, IPR003877, SM00449): SPRY domain
Trm112p (PF03966, IPR005651): Trm112p-like protein
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
169 TRIM72interactor21.0000HrpB7 (PF09486, IPR013392): Bacterial type III secretion protein (HrpB7)
IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
170 TXNDC17interactor21.0000DUF953 (PF06110, IPR010357): Eukaryotic protein of unknown function (DUF953)
Glutaredoxin (PF00462, IPR002109): Glutaredoxin
171 UBA1protein found in more fusions160.29591.247ThiF (PF00899, IPR000594): ThiF family
E1_UFD (PF09358, IPR018965, SM00985): Ubiquitin fold domain
UBA_e1_thiolCys (PF10585, IPR019572): Ubiquitin-activating enzyme active site
172 UBCprotein found in more fusions730.1152507.037ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
173 UBE2Kinteractor310.159392.560UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
174 UBE2V1interactor300.228375.041UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
175 UBE2V2interactor220.260135.647UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
176 UBL5interactor30.6671.000ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
177 UFD1Linteractor60.6005.622UFD1 (PF03152, IPR004854): Ubiquitin fusion degradation protein UFD1
178 USP14interactor50.8001.067UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
179 VASPinteractor80.47613.426ASD2 (PF08687, IPR014799): Apx/Shroom domain ASD2
CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
VASP_tetra (PF08776, IPR014885): VASP tetramerisation domain
WH1 (PF00568, IPR000697, SM00461): WH1 domain
180 VCAM1interactor210.257161.928C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
181 VPS33Binteractor50.4008.571Sec1 (PF00995, IPR001619): Sec1 family
182 XIAPinteractor200.345213.182BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
183 YWHABinteractor300.313365.66714-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
Virulence_fact (PF13769, IPR025989): Virulence factor
184 YWHAEoncoprotein320.333282.84914-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
185 YWHAGprotein found in more fusions290.360219.26514-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
186 YWHAHprotein found in more fusions230.411133.64714-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
187 YWHAQinteractor330.275353.65014-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
188 YWHAZprotein found in more fusions330.317325.31014-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
189 ZDHHC5interactor30.33311.8187TMR-DISM_7TM (PF07695, IPR011623): 7TM diverse intracellular signalling
zf-DHHC (PF01529, IPR001594): DHHC palmitoyltransferase
190 ZNRF1protein found in more fusions70.6677.563zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
RNF220 (PF15926, IPR031824): E3 ubiquitin-protein ligase RNF220
191 ZNRF2interactor50.5009.497zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
SelK_SelG (PF10961, IPR024491): Selenoprotein SelK_SelG
RNF220 (PF15926, IPR031824): E3 ubiquitin-protein ligase RNF220
192 ZNRF3interactor21.0000PA (PF02225, IPR003137): PA domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
Cadherin_C_2 (PF16492, IPR032455): Cadherin cytoplasmic C-terminal
zf-C3H2C3 (PF17122, IPR001841): Zinc-finger
193 ZNRF4interactor100PA (PF02225, IPR003137): PA domain
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger

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