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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)116
The number (and %) of the onco-proteins25 (21.55 %)
The number (and %) of the tumor suppressors6 (5.17 %)
Total number of binary PPIs (saturation %)348 (5.22 %)
The number (and %) of affected PPIs116 (33.33 %)
The number of possible different fusions18
PPI diameter5
PPI radius3
The average degree of PPI5.069
Assortativity coefficient-0.4331
The network average Clustering coefficient0.437
The number (and %) of a zero Clustering coefficients31 (26.72 %)
The number (and %) of a zero Betweenness Centrality49 (42.24 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: UBE2H,RBFOX1 All fusions
Proteins found in more fusions RNF216 (see 1 fusions); RBFOX2 (see 2 fusions); UBE2H (see 4 fusions); MAGED1 (see 1 fusions); PRDX1 (see 1 fusions); EPS15 (see 1 fusions); TRIM28 (see 1 fusions); RNF114 (see 1 fusions); ATN1 (see 1 fusions); QKI (see 3 fusions); PTK2 (see 2 fusions); ATXN1 (see 3 fusions); DAZAP2 (see 2 fusions); DTX3L (see 2 fusions); UBA1 (see 2 fusions); UBA3 (see 1 fusions); RBPMS (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 UBE2Hparental protein790.0258938.089UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
Uteroglobin (PF01099, IPR016126, SM00096): Uteroglobin family
2 RBFOX1parental protein370.1171976.920RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Fox-1_C (PF12414, IPR025670): Calcitonin gene-related peptide regulator C terminal
3 ALG13interactor21.0000Glyco_tran_28_C (PF04101, IPR007235): Glycosyltransferase family 28 C-terminal domain
OTU (PF02338, IPR003323): OTU-like cysteine protease
SMN (PF06003, IPR010304): Survival motor neuron protein (SMN)
4 ANXA6interactor50.7002.167Annexin (PF00191, IPR018502, SM00335): Annexin
5 ATN1protein found in more fusions90.46444.208Atrophin-1 (PF03154, IPR002951): Atrophin-1 family
6 ATXN1protein found in more fusions190.196817.141AXH (PF08517, IPR013723, SM00536): Ataxin-1 and HBP1 module (AXH)
Spt20 (PF12090, IPR021950): Spt20 family
ATXN-1_C (PF12547, IPR020997): Capicua transcriptional repressor modulator
Cnd1_N (PF12922, IPR024324): non-SMC mitotic condensation complex subunit 1, N-term
7 ATXN2interactor31.0000LsmAD (PF06741, IPR009604): LsmAD domain
PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446)
Spt20 (PF12090, IPR021950): Spt20 family
SM-ATX (PF14438, IPR025852): Ataxin 2 SM domain
8 BHLHE40interactor70.467112.310Hairy_orange (PF07527, IPR003650): Hairy Orange
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
9 BRAPinteractor200BRAP2 (PF07576, IPR011422): BRCA1-associated protein 2
DUF87 (PF01935, IPR002789): Domain of unknown function DUF87
zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
KASH_CCD (PF14662, IPR028168): Coiled-coil region of CCDC155 or KASH
10 BYSLinteractor70.190549.219Bystin (PF05291, IPR007955): Bystin
MEA1 (PF06910, IPR009685): Male enhanced antigen 1 (MEA1)
11 C1orf94interactor130.485149.564DUF4688 (PF15752, IPR031496): Domain of unknown function (DUF4688)
12 CBLConcoprotein100Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1
Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain
Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
13 CD99interactor100CD99L2 (PF12301, IPR022078): CD99 antigen like protein 2
14 CELF3interactor100RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
15 CRXinteractor100TF_Otx (PF03529, IPR013851): Otx1 transcription factor
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
16 DAB1interactor90.6397.772PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
17 DAZAP2protein found in more fusions150.418453.305DAZAP2 (PF11029, IPR022730): DAZ associated protein 2 (DAZAP2)
18 DMRTB1interactor31.0000DM (PF00751, IPR001275, SM00301): DM DNA binding domain
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
VIR_N (PF15912, IPR031801): Virilizer, N-terminal
19 DTX3oncoprotein31.0000zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
20 DTX3Lprotein found in more fusions31.0000KH_1 (PF00013, IPR004088, SM00322): KH domain
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
21 DVL2interactor90.214363.859DEP (PF00610, IPR000591, SM00049): Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)
Dishevelled (PF02377, IPR003351): Dishevelled specific domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
DIX (PF00778, IPR001158, SM00021): DIX domain
Dsh_C (PF12316, IPR024580): Segment polarity protein dishevelled (Dsh) C terminal
22 DZIP3interactor70.200273.908DUF16 (PF01519, IPR002862): Protein of unknown function DUF16
SlyX (PF04102, IPR007236): SlyX
zf-RING-like (PF08746, IPR014857): RING-like domain
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
PKcGMP_CC (PF16808, IPR031831): Coiled-coil N-terminus of cGMP-dependent protein kinase
23 ELAVL1oncoprotein240.0831840.070RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
24 EPS15oncoprotein50.5006.891Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391)
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
25 FAM168Ainteractor90.57154.025TCRP1 (PF14944, IPR029247): Tongue Cancer Chemotherapy Resistant Protein 1
26 GCAinteractor40.33342.236EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
DUF2835 (PF11197, IPR021363): Protein of unknown function (DUF2835)
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
27 GOT1interactor40.8330.500Aminotran_1_2 (PF00155, IPR004839): Aminotransferase class I and II
28 HDAC2suppressor50.8337.095Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
29 HDAC6oncoprotein40.6673.519Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
PSGP (PF07276, IPR009900): Apopolysialoglycoprotein (PSGP)
zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
30 HNRNPFinteractor70.286250.937RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Spot_14 (PF07084, IPR009786): Thyroid hormone-inducible hepatic protein Spot 14
zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger
31 HSFX1interactor21.0000HSF_DNA-bind (PF00447, IPR000232, SM00415): HSF-type DNA-binding
32 HSFY1interactor21.0000HSF_DNA-bind (PF00447, IPR000232, SM00415): HSF-type DNA-binding
33 IDH1suppressor50.60035.362Iso_dh (PF00180, IPR024084): Isocitrate/isopropylmalate dehydrogenase
34 JADE1interactor100C1_2 (PF03107, IPR004146): C1 domain
Glyco_hydro_57 (PF03065, IPR004300): Glycosyl hydrolase family 57
EPL1 (PF10513, IPR019542): Enhancer of polycomb-like
eIF-5_eIF-2B (PF01873, IPR002735, SM00653): Domain found in IF2B/IF5
PHD_2 (PF13831): PHD-finger
zf-HC5HC2H_2 (PF13832): PHD-zinc-finger like domain
35 KIFAP3interactor100KAP (PF05804): Kinesin-associated protein (KAP)
36 KLC1interactor2044.324Gly_radical (PF01228, IPR001150): Glycine radical
SOGA (PF11365, IPR027881): Protein SOGA
TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat
TPR_12 (PF13424): Tetratricopeptide repeat
JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II
37 LACTB2interactor30.6671.000E2_bind (PF08825, IPR014929): E2 binding domain
Lactamase_B (PF00753, IPR001279, SM00849): Metallo-beta-lactamase superfamily
Metallophos_3 (PF14582, IPR029461): Metallophosphoesterase, calcineurin superfamily
38 LRSAM1interactor60.200328.932Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
39 LZTS2suppressor60.33386.558CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
DUF1127 (PF06568, IPR009506): Domain of unknown function (DUF1127)
Fez1 (PF06818): Fez1
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
DUF4250 (PF14056, IPR025346): Domain of unknown function (DUF4250)
40 MAGED1protein found in more fusions140.333309.798MAGE (PF01454, IPR002190): MAGE family
41 MARCH1interactor100zf-CSL (PF05207, IPR007872): CSL zinc finger
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
RINGv (PF12906, IPR011016, SM00744): RING-variant domain
42 MARCH10interactor100RINGv (PF12906, IPR011016, SM00744): RING-variant domain
PARM (PF17061, IPR031431): PARM
43 MARCH2interactor21.0000Vpu (PF00558, IPR008187): Vpu protein
RINGv (PF12906, IPR011016, SM00744): RING-variant domain
44 MARCH4interactor100Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
RINGv (PF12906, IPR011016, SM00744): RING-variant domain
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
45 MARCH8interactor100DctQ (PF04290, IPR007387): Tripartite ATP-independent periplasmic transporters, DctQ component
RINGv (PF12906, IPR011016, SM00744): RING-variant domain
46 MKRN3oncoprotein60.40012.701zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
MKRN1_C (PF15815, IPR031644): E3 ubiquitin-protein ligase makorin-1, C-terminal
Torus (PF16131, IPR032297): Torus domain
zf-3CxxC_2 (PF17180): Zinc-binding domain
47 MTAPsuppressor40.66720.794PNP_UDP_1 (PF01048, IPR000845): Phosphorylase superfamily
48 NEURL1suppressor21.0000Neuralized (PF07177, IPR006573, SM00588): Neuralized
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
49 NHLRC1interactor3058.816NHL (PF01436, IPR001258): NHL repeat
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
50 NOC2Linteractor40.33388.108CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
DNA_pol_phi (PF04931, IPR007015): DNA polymerase phi
Noc2 (PF03715, IPR005343): Noc2p family
CEND1 (PF15677, IPR020162): Cell cycle exit and neuronal differentiation protein 1
51 NUMBLinteractor40.6672.881DUF1932 (PF09130, IPR015814): Domain of unknown function (DUF1932)
NumbF (PF06311, IPR010449): NUMB domain
PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
DUF2722 (PF10846, IPR021216): Protein of unknown function (DUF2722)
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
52 PCBP4interactor21.0000KH_1 (PF00013, IPR004088, SM00322): KH domain
53 PLK4interactor40.6671.083ABC1 (PF03109, IPR004147): ABC1 family
Pkinase (PF00069, IPR000719): Protein kinase domain
POLO_box (PF00659, IPR000959): POLO box duplicated region
DUF4520 (PF15016, IPR027865): Domain of unknown function (DUF4520)
54 POLLinteractor21.0000HHH (PF00633, IPR000445): Helix-hairpin-helix motif
DNA_pol_lambd_f (PF10391, IPR018944): Fingers domain of DNA polymerase lambda
HHH_5 (PF14520): Helix-hairpin-helix domain
HHH_8 (PF14716, IPR010996): Helix-hairpin-helix domain
DNA_pol_B_thumb (PF14791, IPR029398): DNA polymerase beta thumb
DNA_pol_B_palm (PF14792, IPR028207): DNA polymerase beta palm
BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
55 POLMinteractor100HHH_8 (PF14716, IPR010996): Helix-hairpin-helix domain
DNA_pol_B_thumb (PF14791, IPR029398): DNA polymerase beta thumb
56 PRDX1oncoprotein60.300107.937AhpC-TSA (PF00578, IPR000866): AhpC/TSA family
1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin
57 PRDX2interactor40.5005.019AhpC-TSA (PF00578, IPR000866): AhpC/TSA family
1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin
58 PRR20Ainteractor80.8573.525PRR20 (PF15708, IPR031439): Proline-rich protein family 20
59 PRRC2Ainteractor50.60045.437BAT2_N (PF07001, IPR009738): BAT2 N-terminus
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
60 PSMF1interactor50.8330.400PI31_Prot_C (PF08577, IPR013886): PI31 proteasome regulator
PI31_Prot_N (PF11566, IPR021625): PI31 proteasome regulator N-terminal
61 PTK2protein found in more fusions40.66713.902FERM_M (PF00373, IPR019748): FERM central domain
Focal_AT (PF03623, IPR005189): Focal adhesion targeting region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
UCMA (PF17085, IPR031386): Unique cartilage matrix associated protein
62 QKIprotein found in more fusions80.476237.741KH_1 (PF00013, IPR004088, SM00322): KH domain
STAR_dimer (PF16544, IPR032377): Homodimerisation region of STAR domain protein
Quaking_NLS (PF16551, IPR032367): Putative nuclear localisation signal of quaking
63 RAG1interactor200zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
zf-RAG1 (PF10426, IPR019485): Recombination-activating protein 1 zinc-finger domain
RAG1_imp_bd (PF12560): RAG1 importin binding
RAG1 (PF12940, IPR024627): Recombination-activation protein 1 (RAG1), recombinase
64 RBFOX2protein found in more fusions170.375385.504RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Fox-1_C (PF12414, IPR025670): Calcitonin gene-related peptide regulator C terminal
65 RBM24interactor100RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RskA (PF10099, IPR018764): Anti-sigma-K factor rskA
TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence
66 RBPMSprotein found in more fusions150.44054.535RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
67 RELAoncoprotein41.0000DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
68 RHOXF2interactor120.50939.910DUF367 (PF04034, IPR007177): Domain of unknown function (DUF367)
GRP (PF07172, IPR010800): Glycine rich protein family
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
69 RNF10interactor100GCS2 (PF04107, IPR006336): Glutamate-cysteine ligase family 2(GCS2)
IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
RNA_pol_Rpb2_5 (PF04567, IPR007647): RNA polymerase Rpb2, domain 5
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
zf-RING_6 (PF14835): zf-RING of BARD1-type protein
70 RNF103interactor100VWC (PF00093, IPR001007, SM00214): von Willebrand factor type C domain
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
71 RNF113Binteractor100zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
72 RNF114protein found in more fusions60.50010.932zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding
HypA (PF01155, IPR000688): Hydrogenase/urease nickel incorporation, metallochaperone, hypA
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain
73 RNF128interactor200CcmD (PF04995, IPR007078): Heme exporter protein D (CcmD)
PA (PF02225, IPR003137): PA domain
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
74 RNF133interactor100PA (PF02225, IPR003137): PA domain
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
75 RNF139oncoprotein100zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
TRC8_N (PF13705, IPR025754): TRC8 N-terminal domain
Prok-RING_1 (PF14446): Prokaryotic RING finger family 1
76 RNF144Asuppressor200IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
77 RNF146interactor200WWE (PF02825, IPR004170, SM00678): WWE domain
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
78 RNF166interactor21.0000zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding
zinc-ribbons_6 (PF07191, IPR010807): zinc-ribbons
Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
zinc_ribbon_2 (PF13240, IPR026870): zinc-ribbon domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain
79 RNF185interactor40183.168zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
80 RNF186interactor100zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
81 RNF2interactor120.200466.502zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
82 RNF216oncoprotein200DUF226 (PF02890, IPR004180): Borrelia family of unknown function DUF226
IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
DUF4645 (PF15488, IPR027891): Domain of unknown function (DUF4645)
83 RNF34interactor21.0000Cwf_Cwc_15 (PF04889, IPR006973): Cwf15/Cwc15 cell cycle control protein
FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
SAP (PF02037, IPR003034, SM00513): SAP domain
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
84 RNF38interactor60.50027.798zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
85 RNF4interactor50.333141.682Sgf11 (PF08209, IPR013246): Sgf11 (transcriptional regulation protein)
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
zf-UDP (PF14569, IPR027934): Zinc-binding RING-finger
86 RNF6interactor100zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
FANCL_C (PF11793, IPR026850): FANCL C-terminal domain
87 SEC23IPinteractor30.6671.000DDHD (PF02862, IPR004177, SM01127): DDHD domain
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
WWE (PF02825, IPR004170, SM00678): WWE domain
88 SNRPNinteractor2052.523LSM (PF01423, IPR001163): LSM domain
89 SSU72interactor40.5003.000Ssu72 (PF04722, IPR006811): Ssu72-like protein
90 STAM2interactor40.333167.355GAT (PF03127, IPR004152): GAT domain
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
VHS (PF00790, IPR002014, SM00288): VHS domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
91 THOP1interactor40.6672.000Peptidase_M3 (PF01432, IPR001567): Peptidase family M3
92 TNIP1interactor40.33325.469ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724)
Filament (PF00038, IPR001664): Intermediate filament protein
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
DUF4201 (PF13870, IPR025254): Domain of unknown function (DUF4201)
FlxA (PF14282, IPR025577): FlxA-like protein
CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
93 TRAIPinteractor60.5008.248Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
ORF6C (PF10552, IPR018878): ORF6C domain
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
94 TRIM17interactor21.0000NlpE (PF04170, IPR007298): NlpE N-terminal domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
zf-Nse (PF11789, IPR004181): Zinc-finger of the MIZ type in Nse subunit
zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
95 TRIM2interactor21.0000Filamin (PF00630, IPR017868): Filamin/ABP280 repeat
NHL (PF01436, IPR001258): NHL repeat
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
ALMT (PF11744, IPR020966): Aluminium activated malate transporter
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
VCBS (PF13517): Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella
Caskin-tail (PF16632, IPR032117): C-terminal region of Caskin
DUF5128 (PF17170): 6-bladed beta-propeller
96 TRIM21interactor50.5005.993DUF313 (PF03754, IPR005508): Domain of unknown function (DUF313)
SPRY (PF00622, IPR003877, SM00449): SPRY domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
Prok-RING_1 (PF14446): Prokaryotic RING finger family 1
zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
97 TRIM23interactor90.28632.727Arf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family
FemAB (PF02388, IPR003447): FemAB family
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
98 TRIM27oncoprotein80.286128.025IncA (PF04156, IPR007285): IncA protein
SPRY (PF00622, IPR003877, SM00449): SPRY domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease
99 TRIM28protein found in more fusions60.300175.357ASFV_J13L (PF05568, IPR008385): African swine fever virus J13L protein
K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
PHD (PF00628, IPR019787, SM00249): PHD-finger
FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2
100 TRIM36interactor200ATP-synt_B (PF00430, IPR002146): ATP synthase B/B' CF(0)
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
zf-RING_10 (PF16685, IPR032043): zinc RING finger of MSL2
101 TRIM37oncoprotein40.6671.797MATH (PF00917, IPR002083, SM00061): MATH domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
Kinetocho_Slk19 (PF12709, IPR024312): Central kinetochore-associated
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
MRFAP1 (PF15155, IPR029254): MORF4 family-associated protein1
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
DUF5071 (PF16804, IPR031837): Domain of unknown function (DUF5071)
102 TRIM5interactor50.5004.923Baculo_IE-1 (PF05290, IPR007954): Baculovirus immediate-early protein (IE-0)
Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus
SPRY (PF00622, IPR003877, SM00449): SPRY domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
103 TRIM56interactor21.0000Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
UPF0547 (PF10571, IPR018886): Uncharacterised protein family UPF0547
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
DUF3583 (PF12126, IPR021978): Protein of unknown function (DUF3583)
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
Phytase-like (PF13449, IPR027372): Esterase-like activity of phytase
104 TRIM72interactor21.0000HrpB7 (PF09486, IPR013392): Bacterial type III secretion protein (HrpB7)
IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
105 TSNAXinteractor40.167151.143Translin (PF01997, IPR002848): Translin family
106 TXNDC17interactor40.6674.494DUF953 (PF06110, IPR010357): Eukaryotic protein of unknown function (DUF953)
Glutaredoxin (PF00462, IPR002109): Glutaredoxin
107 TXNL1interactor40.6674.514PITH (PF06201, IPR010400): PITH domain
Thioredoxin (PF00085, IPR013766): Thioredoxin
108 UBA1protein found in more fusions31.0000ThiF (PF00899, IPR000594): ThiF family
E1_UFD (PF09358, IPR018965, SM00985): Ubiquitin fold domain
UBA_e1_thiolCys (PF10585, IPR019572): Ubiquitin-activating enzyme active site
109 UBA3protein found in more fusions50.5003.000E2_bind (PF08825, IPR014929): E2 binding domain
ThiF (PF00899, IPR000594): ThiF family
110 UBAP2Linteractor40.333243.783CUE (PF02845, IPR003892, SM00546): CUE domain
DUF3484 (PF11983, IPR021873): Membrane-attachment and polymerisation-promoting switch
DUF3697 (PF12478, IPR022166): Ubiquitin-associated protein 2
UBA_4 (PF14555): UBA-like domain
Comm (PF15957, IPR031878): Commissureless
111 UBASH3Binteractor60.400289.944His_Phos_1 (PF00300, IPR013078, SM00855): Histidine phosphatase superfamily (branch 1)
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
2_5_RNA_ligase2 (PF13563): 2'-5' RNA ligase superfamily
SH3_9 (PF14604, IPR001452): Variant SH3 domain
112 UBOX5interactor41.0000U-box (PF04564, IPR003613, SM00504): U-box domain
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
113 UBR2interactor100ClpS (PF02617, IPR003769): ATP-dependent Clp protease adaptor protein ClpS
zinc-ribbons_6 (PF07191, IPR010807): zinc-ribbons
zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box)
zf-ANAPC11 (PF12861, IPR024991): Anaphase-promoting complex subunit 11 RING-H2 finger
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
114 UBR3interactor21.0000zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box)
CRAL_TRIO (PF00650, IPR001251, SM00516): CRAL/TRIO domain
115 UFC1interactor21.0000UFC1 (PF08694, IPR014806): Ubiquitin-fold modifier-conjugating enzyme 1
116 USP5interactor80.214302.621UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein

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