Statistic of PPI	Value(s)
The number of interactors (fusion and proteins)	91
The number (and %) of the onco-proteins	21 (23.08 %)
The number (and %) of the tumor suppressors	7 (7.69 %)
Total number of binary PPIs (saturation %)	226 (5.52 %)
The number (and %) of affected PPIs	90 (39.82 %)
The number of possible different fusions	16
PPI diameter	5
PPI radius	3
The average degree of PPI	4.066
Assortativity coefficient	-0.3711
The network average Clustering coefficient	0.427
The number (and %) of a zero Clustering coefficients	30 (32.97 %)
The number (and %) of a zero Betweenness Centrality	46 (50.55 %)

ACTIVE INTERACTORS

List of the fusions
PPI for parental proteins: CFH,UBE2H	All fusions
Proteins found in more fusions	RNF216 (see 1 fusions); UBE2H (see 4 fusions); PTK2 (see 2 fusions); EP300 (see 1 fusions); VDR (see 2 fusions); GRB2 (see 1 fusions); PRDX1 (see 1 fusions); ZBTB16 (see 3 fusions); EPS15 (see 1 fusions); DTX3L (see 2 fusions); TRIM28 (see 1 fusions); UBA1 (see 2 fusions); UBA3 (see 1 fusions); SMAD3 (see 3 fusions); RNF114 (see 1 fusions);

List of the fusions

PPI for parental proteins: CFH,UBE2H

All fusions

Proteins found in more fusions

RNF216 (see 1 fusions); UBE2H (see 4 fusions); PTK2 (see 2 fusions); EP300 (see 1 fusions); VDR (see 2 fusions); GRB2 (see 1 fusions); PRDX1 (see 1 fusions); ZBTB16 (see 3 fusions); EPS15 (see 1 fusions); DTX3L (see 2 fusions); TRIM28 (see 1 fusions); UBA1 (see 2 fusions); UBA3 (see 1 fusions); SMAD3 (see 3 fusions); RNF114 (see 1 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	CFH	parental protein	11	0.145	744.210	DUF1962 (PF09227, IPR015308): Domain of unknown function (DUF1962) Sushi (PF00084, IPR000436, SM00032): Sushi repeat (SCR repeat)
2	UBE2H	parental protein	79	0.025	6895.641	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme Uteroglobin (PF01099, IPR016126, SM00096): Uteroglobin family
3	ALB	interactor	1	0	0	Serum_albumin (PF00273, IPR014760, SM00103): Serum albumin family
4	ANXA6	interactor	5	0.700	2.167	Annexin (PF00191, IPR018502, SM00335): Annexin
5	BRAP	interactor	2	0	0	BRAP2 (PF07576, IPR011422): BRCA1-associated protein 2 DUF87 (PF01935, IPR002789): Domain of unknown function DUF87 zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain KASH_CCD (PF14662, IPR028168): Coiled-coil region of CCDC155 or KASH
6	BYSL	interactor	4	0.667	2.167	Bystin (PF05291, IPR007955): Bystin MEA1 (PF06910, IPR009685): Male enhanced antigen 1 (MEA1)
7	C3	interactor	1	0	0	A2M (PF00207, IPR001599): Alpha-2-macroglobulin family A2M_comp (PF07678, IPR011626): A-macroglobulin complement component A2M_N (PF01835, IPR002890): MG2 domain A2M_N_2 (PF07703, IPR011625): Alpha-2-macroglobulin family N-terminal region A2M_recep (PF07677, IPR009048): A-macroglobulin receptor ANATO (PF01821, IPR000020, SM00104): Anaphylotoxin-like domain NTR (PF01759, IPR018933, SM00206): UNC-6/NTR/C345C module Thiol-ester_cl (PF10569, IPR019565): Alpha-macro-globulin thiol-ester bond-forming region
8	CBLC	oncoprotein	1	0	0	Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1 Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
9	CD99	interactor	1	0	0	CD99L2 (PF12301, IPR022078): CD99 antigen like protein 2
10	CRP	interactor	1	0	0	Pentaxin (PF00354, IPR001759, SM00159): Pentaxin family
11	DTX3	oncoprotein	3	1.000	0	zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) PRIMA1 (PF16101): Proline-rich membrane anchor 1
12	DTX3L	protein found in more fusions	3	1.000	0	KH_1 (PF00013, IPR004088, SM00322): KH domain zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
13	DZIP3	interactor	5	0.500	3.000	DUF16 (PF01519, IPR002862): Protein of unknown function DUF16 SlyX (PF04102, IPR007236): SlyX zf-RING-like (PF08746, IPR014857): RING-like domain zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2 PKcGMP_CC (PF16808, IPR031831): Coiled-coil N-terminus of cGMP-dependent protein kinase
14	ELAVL1	oncoprotein	18	0.140	347.217	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
15	EP300	oncoprotein	8	0.429	151.198	Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
16	EPS15	oncoprotein	6	0.400	97.838	Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391) EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
17	GOT1	interactor	4	0.833	0.500	Aminotran_1_2 (PF00155, IPR004839): Aminotransferase class I and II
18	GRB2	oncoprotein	11	0.111	689.966	SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093)
19	HDAC2	suppressor	6	0.500	110.136	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
20	HDAC6	oncoprotein	6	0.400	226.102	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain PSGP (PF07276, IPR009900): Apopolysialoglycoprotein (PSGP) zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
21	IDH1	suppressor	5	0.600	6.306	Iso_dh (PF00180, IPR024084): Isocitrate/isopropylmalate dehydrogenase
22	JADE1	interactor	1	0	0	C1_2 (PF03107, IPR004146): C1 domain Glyco_hydro_57 (PF03065, IPR004300): Glycosyl hydrolase family 57 EPL1 (PF10513, IPR019542): Enhancer of polycomb-like eIF-5_eIF-2B (PF01873, IPR002735, SM00653): Domain found in IF2B/IF5 PHD_2 (PF13831): PHD-finger zf-HC5HC2H_2 (PF13832): PHD-zinc-finger like domain
23	LACTB2	interactor	3	0.667	1.000	E2_bind (PF08825, IPR014929): E2 binding domain Lactamase_B (PF00753, IPR001279, SM00849): Metallo-beta-lactamase superfamily Metallophos_3 (PF14582, IPR029461): Metallophosphoesterase, calcineurin superfamily
24	LRSAM1	interactor	4	0.667	1.000	Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) LRR_8 (PF13855, IPR001611): Leucine rich repeat zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
25	MARCH1	interactor	1	0	0	zf-CSL (PF05207, IPR007872): CSL zinc finger zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain RINGv (PF12906, IPR011016, SM00744): RING-variant domain
26	MARCH10	interactor	1	0	0	RINGv (PF12906, IPR011016, SM00744): RING-variant domain PARM (PF17061, IPR031431): PARM
27	MARCH2	interactor	2	1.000	0	Vpu (PF00558, IPR008187): Vpu protein RINGv (PF12906, IPR011016, SM00744): RING-variant domain
28	MARCH4	interactor	1	0	0	Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator RINGv (PF12906, IPR011016, SM00744): RING-variant domain MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
29	MARCH8	interactor	1	0	0	DctQ (PF04290, IPR007387): Tripartite ATP-independent periplasmic transporters, DctQ component RINGv (PF12906, IPR011016, SM00744): RING-variant domain
30	MKRN3	oncoprotein	6	0.400	6.000	zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) MKRN1_C (PF15815, IPR031644): E3 ubiquitin-protein ligase makorin-1, C-terminal Torus (PF16131, IPR032297): Torus domain zf-3CxxC_2 (PF17180): Zinc-binding domain
31	MTAP	suppressor	4	0.667	3.472	PNP_UDP_1 (PF01048, IPR000845): Phosphorylase superfamily
32	NEURL1	suppressor	2	1.000	0	Neuralized (PF07177, IPR006573, SM00588): Neuralized zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
33	NHLRC1	interactor	2	0	0	NHL (PF01436, IPR001258): NHL repeat zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
34	POLL	interactor	2	1.000	0	HHH (PF00633, IPR000445): Helix-hairpin-helix motif DNA_pol_lambd_f (PF10391, IPR018944): Fingers domain of DNA polymerase lambda HHH_5 (PF14520): Helix-hairpin-helix domain HHH_8 (PF14716, IPR010996): Helix-hairpin-helix domain DNA_pol_B_thumb (PF14791, IPR029398): DNA polymerase beta thumb DNA_pol_B_palm (PF14792, IPR028207): DNA polymerase beta palm BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
35	POLM	interactor	1	0	0	HHH_8 (PF14716, IPR010996): Helix-hairpin-helix domain DNA_pol_B_thumb (PF14791, IPR029398): DNA polymerase beta thumb
36	PRDX1	oncoprotein	5	0.500	4.167	AhpC-TSA (PF00578, IPR000866): AhpC/TSA family 1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin
37	PRDX2	interactor	4	0.500	3.000	AhpC-TSA (PF00578, IPR000866): AhpC/TSA family 1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin
38	PTK2	protein found in more fusions	6	0.300	265.653	FERM_M (PF00373, IPR019748): FERM central domain Focal_AT (PF03623, IPR005189): Focal adhesion targeting region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase UCMA (PF17085, IPR031386): Unique cartilage matrix associated protein
39	RAG1	interactor	2	0	0	zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) zf-RAG1 (PF10426, IPR019485): Recombination-activating protein 1 zinc-finger domain RAG1_imp_bd (PF12560): RAG1 importin binding RAG1 (PF12940, IPR024627): Recombination-activation protein 1 (RAG1), recombinase
40	RELA	oncoprotein	6	0.400	322.223	DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
41	RNF10	interactor	2	0	63.338	GCS2 (PF04107, IPR006336): Glutamate-cysteine ligase family 2(GCS2) IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain RNA_pol_Rpb2_5 (PF04567, IPR007647): RNA polymerase Rpb2, domain 5 zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain zf-RING_6 (PF14835): zf-RING of BARD1-type protein
42	RNF103	interactor	1	0	0	VWC (PF00093, IPR001007, SM00214): von Willebrand factor type C domain zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
43	RNF113B	interactor	1	0	0	zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
44	RNF114	protein found in more fusions	6	0.500	4.667	zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding HypA (PF01155, IPR000688): Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain
45	RNF128	interactor	2	0	0	CcmD (PF04995, IPR007078): Heme exporter protein D (CcmD) PA (PF02225, IPR003137): PA domain zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
46	RNF133	interactor	1	0	0	PA (PF02225, IPR003137): PA domain zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
47	RNF139	oncoprotein	1	0	0	zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain TRC8_N (PF13705, IPR025754): TRC8 N-terminal domain Prok-RING_1 (PF14446): Prokaryotic RING finger family 1
48	RNF144A	suppressor	2	0	0	IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
49	RNF146	interactor	2	0	0	WWE (PF02825, IPR004170, SM00678): WWE domain zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
50	RNF166	interactor	2	1.000	0	zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding zinc-ribbons_6 (PF07191, IPR010807): zinc-ribbons Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif zinc_ribbon_2 (PF13240, IPR026870): zinc-ribbon domain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain
51	RNF185	interactor	2	0	0	zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
52	RNF186	interactor	1	0	0	zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
53	RNF2	interactor	10	0.306	44.751	zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
54	RNF216	oncoprotein	2	0	0	DUF226 (PF02890, IPR004180): Borrelia family of unknown function DUF226 IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain DUF4645 (PF15488, IPR027891): Domain of unknown function (DUF4645)
55	RNF34	interactor	2	1.000	0	Cwf_Cwc_15 (PF04889, IPR006973): Cwf15/Cwc15 cell cycle control protein FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger SAP (PF02037, IPR003034, SM00513): SAP domain zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
56	RNF38	interactor	6	0.500	7.742	zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
57	RNF4	interactor	4	0.667	0.667	Sgf11 (PF08209, IPR013246): Sgf11 (transcriptional regulation protein) zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain zf-UDP (PF14569, IPR027934): Zinc-binding RING-finger
58	RNF6	interactor	1	0	0	zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain FANCL_C (PF11793, IPR026850): FANCL C-terminal domain
59	SEC23IP	interactor	3	0.667	1.000	DDHD (PF02862, IPR004177, SM01127): DDHD domain SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) WWE (PF02825, IPR004170, SM00678): WWE domain
60	SELL	interactor	2	1.000	0	EGF (PF00008, IPR000742, SM00181): EGF-like domain Sushi (PF00084, IPR000436, SM00032): Sushi repeat (SCR repeat) Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain MWFE (PF15879, IPR017384): NADH-ubiquinone oxidoreductase MWFE subunit
61	SMAD3	oncoprotein	6	0.700	66.670	MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain
62	SSU72	interactor	4	0.500	3.000	Ssu72 (PF04722, IPR006811): Ssu72-like protein
63	STAM2	interactor	2	1.000	0	GAT (PF03127, IPR004152): GAT domain UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif VHS (PF00790, IPR002014, SM00288): VHS domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
64	THOP1	interactor	4	0.667	2.000	Peptidase_M3 (PF01432, IPR001567): Peptidase family M3
65	TRAIP	interactor	6	0.500	4.667	Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein ORF6C (PF10552, IPR018878): ORF6C domain zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
66	TRIM17	interactor	2	1.000	0	NlpE (PF04170, IPR007298): NlpE N-terminal domain SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-Nse (PF11789, IPR004181): Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
67	TRIM2	interactor	2	1.000	0	Filamin (PF00630, IPR017868): Filamin/ABP280 repeat NHL (PF01436, IPR001258): NHL repeat zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger ALMT (PF11744, IPR020966): Aluminium activated malate transporter zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger VCBS (PF13517): Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Caskin-tail (PF16632, IPR032117): C-terminal region of Caskin DUF5128 (PF17170): 6-bladed beta-propeller
68	TRIM21	interactor	5	0.500	7.813	DUF313 (PF03754, IPR005508): Domain of unknown function (DUF313) SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain Prok-RING_1 (PF14446): Prokaryotic RING finger family 1 zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
69	TRIM23	interactor	9	0.286	33.836	Arf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family FemAB (PF02388, IPR003447): FemAB family zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
70	TRIM27	oncoprotein	9	0.250	262.043	IncA (PF04156, IPR007285): IncA protein SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease
71	TRIM28	protein found in more fusions	5	0.500	2.333	ASFV_J13L (PF05568, IPR008385): African swine fever virus J13L protein K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PHD (PF00628, IPR019787, SM00249): PHD-finger FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2
72	TRIM36	interactor	2	0	0	ATP-synt_B (PF00430, IPR002146): ATP synthase B/B' CF(0) fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger zf-RING_10 (PF16685, IPR032043): zinc RING finger of MSL2
73	TRIM37	oncoprotein	4	0.667	0.667	MATH (PF00917, IPR002083, SM00061): MATH domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger Kinetocho_Slk19 (PF12709, IPR024312): Central kinetochore-associated zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) MRFAP1 (PF15155, IPR029254): MORF4 family-associated protein1 PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain DUF5071 (PF16804, IPR031837): Domain of unknown function (DUF5071)
74	TRIM5	interactor	5	0.500	3.000	Baculo_IE-1 (PF05290, IPR007954): Baculovirus immediate-early protein (IE-0) Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
75	TRIM56	interactor	2	1.000	0	Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein UPF0547 (PF10571, IPR018886): Uncharacterised protein family UPF0547 zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger DUF3583 (PF12126, IPR021978): Protein of unknown function (DUF3583) zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger Phytase-like (PF13449, IPR027372): Esterase-like activity of phytase
76	TRIM72	interactor	2	1.000	0	HrpB7 (PF09486, IPR013392): Bacterial type III secretion protein (HrpB7) IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
77	TXNDC17	interactor	4	0.667	2.000	DUF953 (PF06110, IPR010357): Eukaryotic protein of unknown function (DUF953) Glutaredoxin (PF00462, IPR002109): Glutaredoxin
78	TXNL1	interactor	4	0.667	2.000	PITH (PF06201, IPR010400): PITH domain Thioredoxin (PF00085, IPR013766): Thioredoxin
79	UBA1	protein found in more fusions	4	0.333	81.870	ThiF (PF00899, IPR000594): ThiF family E1_UFD (PF09358, IPR018965, SM00985): Ubiquitin fold domain UBA_e1_thiolCys (PF10585, IPR019572): Ubiquitin-activating enzyme active site
80	UBA3	protein found in more fusions	5	0.500	3.000	E2_bind (PF08825, IPR014929): E2 binding domain ThiF (PF00899, IPR000594): ThiF family
81	UBAP2L	interactor	2	1.000	0	CUE (PF02845, IPR003892, SM00546): CUE domain DUF3484 (PF11983, IPR021873): Membrane-attachment and polymerisation-promoting switch DUF3697 (PF12478, IPR022166): Ubiquitin-associated protein 2 UBA_4 (PF14555): UBA-like domain Comm (PF15957, IPR031878): Commissureless
82	UBASH3B	interactor	4	0.667	63.338	His_Phos_1 (PF00300, IPR013078, SM00855): Histidine phosphatase superfamily (branch 1) UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain 2_5_RNA_ligase2 (PF13563): 2'-5' RNA ligase superfamily SH3_9 (PF14604, IPR001452): Variant SH3 domain
83	UBOX5	interactor	4	1.000	0	U-box (PF04564, IPR003613, SM00504): U-box domain zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
84	UBR2	interactor	1	0	0	ClpS (PF02617, IPR003769): ATP-dependent Clp protease adaptor protein ClpS zinc-ribbons_6 (PF07191, IPR010807): zinc-ribbons zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box) zf-ANAPC11 (PF12861, IPR024991): Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
85	UBR3	interactor	2	1.000	0	zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box) CRAL_TRIO (PF00650, IPR001251, SM00516): CRAL/TRIO domain
86	UFC1	interactor	2	1.000	0	UFC1 (PF08694, IPR014806): Ubiquitin-fold modifier-conjugating enzyme 1
87	USP5	interactor	6	0.400	12.366	UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
88	VDR	suppressor	5	1.000	0	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
89	VPS16	interactor	2	0	46.927	Vps16_C (PF04840, IPR006925): Vps16, C-terminal region Vps16_N (PF04841, IPR006926): Vps16, N-terminal region
90	YTHDC1	interactor	1	0	0	DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family YTH (PF04146, IPR007275): YT521-B-like domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term TFB6 (PF17110, IPR031349): Subunit 11 of the general transcription factor TFIIH
91	ZBTB16	suppressor	8	0.381	243.344	BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger

B a c k t o T o p ⇑

Fusion ID: Protein names:	7328 3075
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