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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins TP53BP2, USP8 (from a repository: Mon Mar 13 06:44:25 2017)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)166
The number (and %) of the onco-proteins44 (26.51 %)
The number (and %) of the tumor suppressors20 (12.05 %)
Total number of binary PPIs (saturation %)1018 (7.43 %)
The number (and %) of affected PPIs171 (16.80 %)
The number of possible different fusions28
PPI diameter4
PPI radius2
The average degree of PPI11.470
Assortativity coefficient-0.2274
The network average Clustering coefficient0.448
The number (and %) of a zero Clustering coefficients12 (7.23 %)
The number (and %) of a zero Betweenness Centrality26 (15.66 %)

ACTIVE INTERACTORS


List of the fusions

Proteins found in more fusions BIRC6 (see 1 fusions); YWHAG (see 1 fusions); CHMP2B (see 1 fusions); EPS15 (see 1 fusions); HNRNPUL1 (see 1 fusions); UBE2G1 (see 1 fusions); EEF1A1 (see 1 fusions); NIN (see 1 fusions); GRB2 (see 1 fusions); SIAH1 (see 4 fusions); OFD1 (see 1 fusions); TCL1A (see 1 fusions); YWHAH (see 2 fusions); CHMP1A (see 2 fusions); TRAF4 (see 1 fusions); BCL2L1 (see 1 fusions); YWHAZ (see 1 fusions); NDC80 (see 1 fusions); EGFR (see 2 fusions); HTT (see 1 fusions); AMOTL2 (see 1 fusions); SIAH2 (see 1 fusions); TXLNA (see 3 fusions); EP300 (see 1 fusions); UBE2E1 (see 2 fusions); UBC (see 1 fusions); TP53 (see 3 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 TP53BP2parental protein1040.08410261.152ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
Erp_C (PF06780, IPR009618): Erp protein C-terminus
SlyX (PF04102, IPR007236): SlyX
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
2 USP8parental protein670.0785664.688DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
USP8_dimer (PF08969, IPR015063): USP8 dimerisation domain
SET (PF00856, IPR001214, SM00317): SET domain
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
Rhodanese (PF00581, IPR001763, SM00450): Rhodanese-like domain
NAM-associated (PF14303, IPR029466): No apical meristem-associated C-terminal domain
3 ACAA2interactor21.0000Thiolase_C (PF02803, IPR020617): Thiolase, C-terminal domain
Thiolase_N (PF00108, IPR020616): Thiolase, N-terminal domain
4 AKT1oncoprotein190.203261.325PH (PF00169, IPR001849, SM00233): PH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
5 AMOToncoprotein210.274216.417FAP (PF07174, IPR010801): Fibronectin-attachment protein (FAP)
Gastrin (PF00918, IPR001651, SM00029): Gastrin/cholecystokinin family
DUF2162 (PF09930, IPR017199): Predicted transporter (DUF2162)
Angiomotin_C (PF12240, IPR024646): Angiomotin C terminal
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
6 AMOTL2protein found in more fusions110.35672.602HOOK (PF05622, IPR008636): HOOK protein
SlyX (PF04102, IPR007236): SlyX
Angiomotin_C (PF12240, IPR024646): Angiomotin C terminal
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
7 ANXA1suppressor120.23696.681Annexin (PF00191, IPR018502, SM00335): Annexin
8 ATPAF2interactor100ATP12 (PF07542, IPR011419): ATP12 chaperone protein
Ribosomal_L14e (PF01929, IPR002784): Ribosomal protein L14
9 ATXN7interactor70.33350.615DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
SCA7 (PF08313, IPR013243): SCA7, zinc-binding domain
Macoilin (PF09726, IPR019130): Transmembrane protein
DUF3505 (PF12013, IPR022698): Protein of unknown function (DUF3505)
IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
10 BAIAP2interactor80.42915.080IMD (PF08397, IPR013606): IRSp53/MIM homology domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
11 BCL2oncoprotein90.57121.730Bcl-2 (PF00452, IPR026298): Apoptosis regulator proteins, Bcl-2 family
BH4 (PF02180, IPR003093, SM00265): Bcl-2 homology region 4
12 BCL2L1oncoprotein100.47241.649Bcl-2 (PF00452, IPR026298): Apoptosis regulator proteins, Bcl-2 family
BH4 (PF02180, IPR003093, SM00265): Bcl-2 homology region 4
13 BECN1suppressor60.50012.365APG6 (PF04111, IPR007243): Autophagy protein Apg6
Ima1_N (PF09779, IPR018617): Ima1 N-terminal domain
BH3 (PF15285, IPR029318): Beclin-1 BH3 domain, Bcl-2-interacting
14 BIRC6oncoprotein80.286123.321BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain
SlyX (PF04102, IPR007236): SlyX
UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
BIRC6 (PF12356, IPR022103): Baculoviral IAP repeat-containing protein 6
ABC_tran_CTD (PF16326, IPR032524): ABC transporter C-terminal domain
15 CCDC85Binteractor80.39317.161CCDC85 (PF10226, IPR019359): CCDC85 family
16 CCDC85Cinteractor230.336138.338bZIP_1 (PF00170, IPR004827): bZIP transcription factor
CCDC85 (PF10226, IPR019359): CCDC85 family
17 CCDC92interactor21.0000Exonuc_VII_L (PF02601, IPR020579): Exonuclease VII, large subunit
CCDC92 (PF14916): Coiled-coil domain of unknown function
18 CENPJinteractor180.38683.542DASH_Hsk3 (PF08227, IPR013183): DASH complex subunit Hsk3 like
DUF1795 (PF08786, IPR014894): Domain of unknown function (DUF1795)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Rota_VP2 (PF05087, IPR007779): Rotavirus VP2 protein
Tcp10_C (PF07202, IPR009852): T-complex protein 10 C-terminus
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
AAA_23 (PF13476): AAA domain
DUF4140 (PF13600, IPR025554): N-terminal domain of unknown function (DUF4140)
19 CEP104interactor80.6796.259ATP-synt_E_2 (PF08112, IPR012508): ATP synthase epsilon subunit
zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding
HEAT (PF02985, IPR000357): HEAT repeat
PRP1_N (PF06424, IPR010491): PRP1 splicing factor, N-terminal
UVR (PF02151, IPR001943): UvrB/uvrC motif
zf-BED (PF02892, IPR003656, SM00614): BED zinc finger
CLASP_N (PF12348, IPR024395): CLASP N terminal
DZR (PF12773, IPR025874): Double zinc ribbon
zf-C2H2_4 (PF13894): C2H2-type zinc finger
20 CEP120interactor140.69217.297C2 (PF00168, IPR000008, SM00239): C2 domain
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
DUF3668 (PF12416, IPR022136): Cep120 protein
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
21 CEP128interactor310.400200.961DUF1129 (PF06570, IPR009214): Protein of unknown function (DUF1129)
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
SpoOE-like (PF09388, IPR018540): Spo0E like sporulation regulatory protein
DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968)
TraF_2 (PF13729, IPR032811): F plasmid transfer operon, TraF, protein
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
HAUS6_N (PF14661, IPR028163): HAUS augmin-like complex subunit 6 N-terminus
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
22 CEP135interactor170.566136.135DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724)
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
LPP (PF04728, IPR006817): Lipoprotein leucine-zipper
RasGAP_C (PF03836, IPR000593): RasGAP C-terminus
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
TPD52 (PF04201, IPR007327): Tumour protein D52 family
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
zf-C4H2 (PF10146, IPR018482): Zinc finger-containing protein
KASH_CCD (PF14662, IPR028168): Coiled-coil region of CCDC155 or KASH
HMMR_N (PF15905, IPR031787): Hyaluronan mediated motility receptor N-terminal
GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor
PKcGMP_CC (PF16808, IPR031831): Coiled-coil N-terminus of cGMP-dependent protein kinase
23 CEP152interactor150.56223.701bZIP_1 (PF00170, IPR004827): bZIP transcription factor
CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding
CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641)
ZapB (PF06005, IPR009252): Cell division protein ZapB
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Ribosomal_S13 (PF00416, IPR001892): Ribosomal protein S13/S18
FAD-SLDH (PF12318, IPR024651): Membrane bound FAD containing D-sorbitol dehydrogenase
YtxH (PF12732, IPR024623): YtxH-like protein
ADH_zinc_N_2 (PF13602): Zinc-binding dehydrogenase
TolA_bind_tri (PF16331, IPR032519): TolA binding protein trimerisation
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
24 CEP162interactor190.532102.285DivIC (PF04977, IPR007060): Septum formation initiator
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
Methyltransf_14 (PF08484, IPR013691): C-methyltransferase C-terminal domain
OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Phage_GP20 (PF06810, IPR009636): Phage minor structural protein GP20
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5
DUF2553 (PF10830, IPR020140): Protein of unknown function (DUF2553)
DUF3073 (PF11273, IPR021426): Protein of unknown function (DUF3073)
PIP49_N (PF14875, IPR029244): N-term cysteine-rich ER, FAM69
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
FAM76 (PF16046, IPR032017): FAM76 protein
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
25 CEP44interactor70.8571.183DUF16 (PF01519, IPR002862): Protein of unknown function DUF16
NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein
Utp12 (PF04003, IPR007148): Dip2/Utp12 Family
CEP44 (PF15007, IPR029157): Centrosomal spindle body, CEP44
26 CEP89interactor150.61026.092ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
CorA (PF01544, IPR002523): CorA-like Mg2+ transporter protein
Exonuc_VII_L (PF02601, IPR020579): Exonuclease VII, large subunit
Lectin_N (PF03954, IPR005640): Hepatic lectin, N-terminal domain
Spc24 (PF08286, IPR013252): Spc24 subunit of Ndc80
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
27 CEP97interactor140.53838.275IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
LRR_8 (PF13855, IPR001611): Leucine rich repeat
LRR_9 (PF14580): Leucine-rich repeat
28 CHMP1Aprotein found in more fusions60.50018.484Snf7 (PF03357, IPR005024): Snf7
29 CHMP1Binteractor50.33354.868Snf7 (PF03357, IPR005024): Snf7
30 CHMP2Ainteractor50.33341.042Snf7 (PF03357, IPR005024): Snf7
31 CHMP2Bprotein found in more fusions31.0000Involucrin (PF00904, IPR000354): Involucrin repeat
Snf7 (PF03357, IPR005024): Snf7
32 CHMP4Cinteractor31.0000Snf7 (PF03357, IPR005024): Snf7
33 CHMP7interactor203.668Snf7 (PF03357, IPR005024): Snf7
34 CNTRLoncoprotein160.6929.803APG6 (PF04111, IPR007243): Autophagy protein Apg6
BcrAD_BadFG (PF01869, IPR002731): BadF/BadG/BcrA/BcrD ATPase family
DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Fez1 (PF06818): Fez1
Laminin_II (PF06009, IPR010307): Laminin Domain II
Ly49 (PF08391, IPR013600): Ly49-like protein, N-terminal region
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal
TBPIP (PF07106, IPR010776): Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
TMPIT (PF07851, IPR012926): TMPIT-like protein
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5
DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968)
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
LRR_9 (PF14580): Leucine-rich repeat
35 CNTROBinteractor90.6943.455DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724)
FadA (PF09403, IPR018543): Adhesion protein FadA
Flavodoxin_5 (PF12724, IPR026816): Flavodoxin domain
DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472)
36 CPVLinteractor90.33342.843Peptidase_S10 (PF00450, IPR001563): Serine carboxypeptidase
37 CSNK2Binteractor140.333115.379CK_II_beta (PF01214, IPR000704, SM01085): Casein kinase II regulatory subunit
38 CWF19L2interactor309.788CwfJ_C_1 (PF04677, IPR006768): Protein similar to CwfJ C-terminus 1
CwfJ_C_2 (PF04676, IPR006767): Protein similar to CwfJ C-terminus 2
DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755)
Pap_E4 (PF02711, IPR003861): E4 protein
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
DUF4519 (PF15012, IPR027960): Domain of unknown function (DUF4519)
MRI (PF15325, IPR028278): Modulator of retrovirus infection
39 DCUN1D1interactor90.38928.894Cullin_binding (PF03556, IPR005176): Cullin binding
UBA_4 (PF14555): UBA-like domain
40 DYNLT1interactor21.0000Tctex-1 (PF03645, IPR005334): Tctex-1 family
41 EEF1A1suppressor140.295126.969GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
42 EGFRoncoprotein300.217653.402Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
43 EP300oncoprotein170.225289.039Creb_binding (PF09030, IPR014744): Creb binding
DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902)
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
KIX (PF02172, IPR003101): KIX domain
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger
HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
44 EPS15oncoprotein110.44456.323Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391)
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
45 ERBB4suppressor90.42979.371Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
DUF3951 (PF13131, IPR025028): Protein of unknown function (DUF3951)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
46 FARSBinteractor50.40022.724B3_4 (PF03483, IPR005146, SM00873): B3/4 domain
B5 (PF03484, IPR005147, SM00874): tRNA synthetase B5 domain
47 FBF1interactor170.309149.546DUF737 (PF05300, IPR007964): Protein of unknown function (DUF737)
OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Sacchrp_dh_NADP (PF03435, IPR005097): Saccharopine dehydrogenase NADP binding domain
Spc24 (PF08286, IPR013252): Spc24 subunit of Ndc80
Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14
Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family
YlqD (PF11068, IPR021297): YlqD protein
KfrA_N (PF11740, IPR021104): Plasmid replication region DNA-binding N-term
48 FRMD6interactor90.47214.857FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
HTH_24 (PF13412, IPR011991): Winged helix-turn-helix DNA-binding
49 GRAP2interactor50.5004.101NADH_dhqG_C (PF09326, IPR015405): NADH-ubiquinone oxidoreductase subunit G, C-terminal
SH2 (PF00017, IPR000980, SM00252): SH2 domain
DUF2076 (PF09849, IPR018648): Uncharacterized protein conserved in bacteria (DUF2076)
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
50 GRB2oncoprotein260.283635.628SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093)
51 HIST1H2BCinteractor100Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
52 HIST2H2ACinteractor60.6679.677Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
53 HIST2H2BEinteractor80.42942.919Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
54 HNRNPUL1protein found in more fusions100.36141.942Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
Rox3 (PF08633, IPR013942): Rox3 mediator complex subunit
SAP (PF02037, IPR003034, SM00513): SAP domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
AAA_33 (PF13671): AAA domain
PRIMA1 (PF16101): Proline-rich membrane anchor 1
55 HOMER1interactor21.0000WH1 (PF00568, IPR000697, SM00461): WH1 domain
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
56 HSPA4interactor160.333134.338Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region
HSP70 (PF00012, IPR013126): Hsp70 protein
TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5
57 HSPH1oncoprotein70.38160.553HSP70 (PF00012, IPR013126): Hsp70 protein
SICA_alpha (PF12887, IPR024290): SICA extracellular alpha domain
58 HTTprotein found in more fusions100.27883.245HEAT (PF02985, IPR000357): HEAT repeat
SPX (PF03105, IPR004331): SPX domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
DUF3652 (PF12372, IPR024613): Huntingtin protein region
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
59 ITCHinteractor200.187669.362C2 (PF00168, IPR000008, SM00239): C2 domain
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
60 KCNN4interactor100CaMBD (PF02888, IPR004178, SM01053): Calmodulin binding domain
Ion_trans_2 (PF07885, IPR013099): Ion channel
SK_channel (PF03530, IPR015449): Calcium-activated SK potassium channel
61 KIF23interactor140.341142.582DUF730 (PF05325, IPR007989): Protein of unknown function (DUF730)
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
MKLP1_Arf_bdg (PF16540, IPR032384): Arf6-interacting domain of mitotic kinesin-like protein 1
62 KIF5Ainteractor30.6670.656ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724)
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
BLOC1_2 (PF10046, IPR019269): Biogenesis of lysosome-related organelles complex-1 subunit 2
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
Microtub_bd (PF16796, IPR031852): Microtubule binding
63 KRT31interactor110.164161.065Filament (PF00038, IPR001664): Intermediate filament protein
64 KRT36interactor31.0000Filament (PF00038, IPR001664): Intermediate filament protein
65 KRT85interactor50.6003.102Filament (PF00038, IPR001664): Intermediate filament protein
Keratin_2_head (PF16208, IPR032444): Keratin type II head
66 LATS2suppressor230.346190.823Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
67 LMO4interactor70.42920.159LIM (PF00412, IPR001781, SM00132): LIM domain
zf-dskA_traR (PF01258, IPR000962): Prokaryotic dksA/traR C4-type zinc finger
68 LRIG1suppressor31.0000I-set (PF07679, IPR013098): Immunoglobulin I-set domain
LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
LRR_2 (PF07723, IPR013101): Leucine Rich Repeat
LRRCT (PF01463, IPR000483, SM00082): Leucine rich repeat C-terminal domain
LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
Ig_3 (PF13927): Immunoglobulin domain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
69 MAPK8IP2interactor50.33310.873BUD22 (PF09073, IPR015158): BUD22
CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
SH3_9 (PF14604, IPR001452): Variant SH3 domain
70 MCPH1suppressor21.0000BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
MSP (PF01716, IPR002628): Manganese-stabilising protein / photosystem II polypeptide
Spectrin (PF00435, IPR002017): Spectrin repeat
Microcephalin (PF12258, IPR022047): Microcephalin protein
PTCB-BRCT (PF12738, IPR001357): twin BRCT domain
BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
71 MED4interactor230.379225.002Med4 (PF10018, IPR019258): Vitamin-D-receptor interacting Mediator subunit 4
72 MRPL20interactor100Herpes_UL49_5 (PF05702, IPR008647): Herpesvirus UL49.5 envelope/tegument protein
Ribosomal_L20 (PF00453, IPR005813): Ribosomal protein L20
73 MTMR14interactor100Myotub-related (PF06602, IPR010569): Myotubularin-like phosphatase domain
Y_phosphatase3 (PF13350, IPR026893): Tyrosine phosphatase family
74 NAE1interactor40.33352.742ThiF (PF00899, IPR000594): ThiF family
75 NBR1oncoprotein50.33331.640CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
PB1 (PF00564, IPR000270, SM00666): PB1 domain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
DUF2681 (PF10883, IPR020274): Protein of unknown function (DUF2681)
N_BRCA1_IG (PF16158, IPR032350): Ig-like domain from next to BRCA1 gene
76 NDC80protein found in more fusions120.43637.994DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
Ly49 (PF08391, IPR013600): Ly49-like protein, N-terminal region
Ndc80_HEC (PF03801, IPR005550): HEC/Ndc80p family
SlyX (PF04102, IPR007236): SlyX
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein
77 NINoncoprotein160.54326.560BRE1 (PF08647, IPR013956): BRE1 E3 ubiquitin ligase
bZIP_1 (PF00170, IPR004827): bZIP transcription factor
DivIC (PF04977, IPR007060): Septum formation initiator
DivIVA (PF05103, IPR007793): DivIVA protein
DUF342 (PF03961, IPR005646): Protein of unknown function (DUF342)
ZapB (PF06005, IPR009252): Cell division protein ZapB
FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC)
Fzo_mitofusin (PF04799, IPR006884): fzo-like conserved region
Cnn_1N (PF07989, IPR012943): Centrosomin N-terminal motif 1
Rho_Binding (PF08912, IPR015008): Rho Binding
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
DUF2205 (PF10224, IPR019357): Predicted coiled-coil protein (DUF2205)
Kinetocho_Slk19 (PF12709, IPR024312): Central kinetochore-associated
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
Cep57_CLD_2 (PF14197, IPR025925): Centrosome localisation domain of PPC89
FlxA (PF14282, IPR025577): FlxA-like protein
DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472)
Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein
DUF4665 (PF15679, IPR031389): Domain of unknown function (DUF4665)
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
78 NINLinteractor170.50747.084PD40 (PF07676, IPR011659): WD40-like Beta Propeller Repeat
TBCA (PF02970, IPR004226): Tubulin binding cofactor A
DUF2389 (PF09493, IPR012663): Tryptophan-rich protein (DUF2389)
Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5
EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein
FAM184 (PF15665): Family with sequence similarity 184, A and B
TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain
79 NTRK1oncoprotein380.1731141.209I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
80 NUTM1oncoprotein21.0000NUT (PF12881, IPR024309): NUT protein
81 NXF1interactor280.120816.861NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding
TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
82 ODF2interactor130.7317.371ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
NAT (PF04768, IPR006855): NAT, N-acetyltransferase, of N-acetylglutamate synthase
Invasin_D3 (PF09134, IPR015217): Invasin, domain 3
Mt_ATP-synt_D (PF05873, IPR008689): ATP synthase D chain, mitochondrial (ATP5H)
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
83 OFD1protein found in more fusions330.363324.209APG6 (PF04111, IPR007243): Autophagy protein Apg6
Exonuc_VII_L (PF02601, IPR020579): Exonuclease VII, large subunit
GrpE (PF01025, IPR000740): GrpE
NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein
XhlA (PF10779, IPR019715): Haemolysin XhlA
DUF3372 (PF11852, IPR024561): Domain of unknown function (DUF3372)
LisH_2 (PF16045, IPR006594): LisH
84 OTUB1interactor180.261250.421Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain
85 OTUB2interactor100.267251.223Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain
86 PARD3interactor190.368119.813PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
DUF3534 (PF12053, IPR021922): Domain of unknown function (DUF3534)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
87 PARD6Ainteractor70.7623.719PB1 (PF00564, IPR000270, SM00666): PB1 domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
88 PARD6Binteractor70.7621.921PB1 (PF00564, IPR000270, SM00666): PB1 domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
89 PCM1oncoprotein330.331291.429FliD_N (PF02465, IPR003481): Flagellar hook-associated protein 2 N-terminus
FUSC (PF04632, IPR006726): Fusaric acid resistance protein family
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein
Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family
RseA_C (PF03873, IPR005573): Anti sigma-E protein RseA, C-terminal domain
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
V_ATPase_I (PF01496, IPR002490): V-type ATPase 116kDa subunit family
AAA_23 (PF13476): AAA domain
zf-C4pol (PF14260, IPR025687): C4-type zinc-finger of DNA polymerase delta
PCM1_C (PF15717, IPR031446): Pericentriolar material 1 C terminus
DUF4829 (PF16111, IPR032256): Domain of unknown function (DUF4829)
90 PJA1interactor70.7337.876zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
91 PLA2G2Asuppressor50.8333.668Phospholip_A2_1 (PF00068, IPR016090, SM00085): Phospholipase A2
92 PLEKHN1interactor100PH (PF00169, IPR001849, SM00233): PH domain
93 PLK1suppressor230.332299.612Pkinase (PF00069, IPR000719): Protein kinase domain
POLO_box (PF00659, IPR000959): POLO box duplicated region
94 POLD3interactor30.33331.233CDC27 (PF09507, IPR019038): DNA polymerase subunit Cdc27
95 POLR2Linteractor30.33318.281RNA_pol_N (PF01194, IPR000268): RNA polymerases N / 8 kDa subunit
96 PPHLN1interactor50.6005.985Lge1 (PF11488): Transcriptional regulatory protein LGE1
HERV-K_REC (PF15695): Rec (regulator of expression encoded by corf) of HERV-K-113
97 PPP1CAsuppressor280.235532.567Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
98 PPP1CBinteractor160.333143.042Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
99 PPP1CConcoprotein200.274186.444Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
100 PPP1R2interactor90.33390.945IPP-2 (PF04979, IPR007062): Protein phosphatase inhibitor 2 (IPP-2)
101 PPP1R3Ainteractor60.6673.467CBM_21 (PF03370, IPR005036): Carbohydrate/starch-binding module (family 21)
102 PRKAB2interactor31.0000AMPKBI (PF04739, IPR006828, SM01010): 5'-AMP-activated protein kinase beta subunit, interaction domain
AMPK1_CBM (PF16561, IPR032640): Glycogen recognition site of AMP-activated protein kinase
103 PRPF31interactor70.40023.727Nop (PF01798, IPR002687): snoRNA binding domain, fibrillarin
Cytokin_check_N (PF10407, IPR018844): Cdc14 phosphatase binding protein N-terminus
Prp31_C (PF09785, IPR019175): Prp31 C terminal domain
104 PTENsuppressor90.30666.487DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein
105 PTNoncoprotein31.0000PTN_MK_C (PF01091, IPR020090): PTN/MK heparin-binding protein family, C-terminal domain
PTN_MK_N (PF05196, IPR020089): PTN/MK heparin-binding protein family, N-terminal domain
106 PTPN23suppressor80.6797.825BRO1 (PF03097, IPR004328, SM01041): BRO1-like domain
Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
SOGA (PF11365, IPR027881): Protein SOGA
ALIX_LYPXL_bnd (PF13949, IPR025304): ALIX V-shaped domain binding to HIV
107 RASSF10suppressor80.42913.097DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
FliJ (PF02050, IPR012823): Flagellar FliJ protein
Mt_ATP-synt_B (PF05405, IPR008688): Mitochondrial ATP synthase B chain precursor (ATP-synt_B)
PAP_RNA-bind (PF04926, IPR007010): Poly(A) polymerase predicted RNA binding domain
RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain
IMUP (PF15761, IPR026621): Immortalisation up-regulated protein
108 RASSF7interactor110.364161.528RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain
SlyX (PF04102, IPR007236): SlyX
Tryp_alpha_amyl (PF00234, IPR016140, SM00499): Protease inhibitor/seed storage/LTP family
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
109 RASSF8suppressor170.36061.481ETC_C1_NDUFA5 (PF04716, IPR006806): ETC complex I subunit conserved region
FliD_C (PF07195, IPR010809): Flagellar hook-associated protein 2 C-terminus
PEARLI-4 (PF05278, IPR007942): Arabidopsis phospholipase-like protein (PEARLI 4)
RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain
TBPIP (PF07106, IPR010776): Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
110 RASSF9interactor100.55620.584RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain
Spore_III_AB (PF09548, IPR014198): Stage III sporulation protein AB (spore_III_AB)
DUF3087 (PF11286, IPR021438): Protein of unknown function (DUF3087)
111 RNF128interactor60.7006.489CcmD (PF04995, IPR007078): Heme exporter protein D (CcmD)
PA (PF02225, IPR003137): PA domain
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
112 RNF41interactor40.6670.721Sina (PF03145, IPR018121): Seven in absentia protein family
USP8_interact (PF08941, IPR015036): USP8 interacting
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
113 RPGRIP1interactor31.0000C2 (PF00168, IPR000008, SM00239): C2 domain
CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
RNA_binding (PF01877, IPR002739): RNA binding
DUF3037 (PF11236, IPR021398): Protein of unknown function (DUF3037)
C2-C2_1 (PF11618, IPR021656): First C2 domain of RPGR-interacting protein 1
COX16 (PF14138, IPR020164): Cytochrome c oxidase assembly protein COX16
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
114 RPGRIP1Linteractor150.55245.005bZIP_1 (PF00170, IPR004827): bZIP transcription factor
C2 (PF00168, IPR000008, SM00239): C2 domain
DivIC (PF04977, IPR007060): Septum formation initiator
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
FtsL (PF04999, IPR011922): Cell division protein FtsL
T3SS_needle_F (PF09392, IPR021123): Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
C2-C2_1 (PF11618, IPR021656): First C2 domain of RPGR-interacting protein 1
BNIP2 (PF12496, IPR022181): Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
DUF4497 (PF14924): Protein of unknown function (DUF4497)
115 RPL6P1interactor100NA
116 SCLT1oncoprotein100.42229.775DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
SlyX (PF04102, IPR007236): SlyX
XhlA (PF10779, IPR019715): Haemolysin XhlA
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
Imm7 (PF15585, IPR028965): Immunity protein 7
CCCAP (PF15964, IPR031887): Centrosomal colon cancer autoantigen protein family
DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
117 SCNN1Ainteractor40.5007.334ASC (PF00858, IPR001873): Amiloride-sensitive sodium channel
118 SCNN1Boncoprotein40.50013.224ASC (PF00858, IPR001873): Amiloride-sensitive sodium channel
119 SCNN1Ginteractor21.0000ASC (PF00858, IPR001873): Amiloride-sensitive sodium channel
120 SFNsuppressor160.343101.06514-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
121 SGF29interactor50.50020.226DUF1325 (PF07039, IPR010750): SGF29 tudor-like domain
Filament (PF00038, IPR001664): Intermediate filament protein
122 SIAH1suppressor110.22277.234Sina (PF03145, IPR018121): Seven in absentia protein family
123 SIAH2oncoprotein50.5007.704Sina (PF03145, IPR018121): Seven in absentia protein family
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
124 SPP1oncoprotein4062.054Osteopontin (PF00865, IPR002038, SM00017): Osteopontin
125 SRConcoprotein80.42972.650Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
126 SRGAP3suppressor21.0000CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
Med9 (PF07544, IPR011425): RNA polymerase II transcription mediator complex subunit 9
DUF16 (PF01519, IPR002862): Protein of unknown function DUF16
FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain
FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC)
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
TMPIT (PF07851, IPR012926): TMPIT-like protein
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
DUF4164 (PF13747, IPR025310): Domain of unknown function (DUF4164)
127 SSX2IPinteractor280.333241.539ZapB (PF06005, IPR009252): Cell division protein ZapB
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
Surfac_D-trimer (PF09006, IPR015097): Lung surfactant protein D coiled-coil trimerisation
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
YqzH (PF14164, IPR025546): YqzH-like protein
128 STAMinteractor160.300183.043GAT (PF03127, IPR004152): GAT domain
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
VHS (PF00790, IPR002014, SM00288): VHS domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
129 STAM2interactor110.455159.816GAT (PF03127, IPR004152): GAT domain
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
VHS (PF00790, IPR002014, SM00288): VHS domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
130 STAT6oncoprotein40.50012.314SH2 (PF00017, IPR000980, SM00252): SH2 domain
STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain
STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain
STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
STAT6_C (PF14596, IPR028187): STAT6 C-terminal
131 TANKsuppressor41.0000DUF3713 (PF12506, IPR022186): Protein of unknown function (DUF3713)
TBD (PF12845, IPR024581): TBD domain
132 TARDBPinteractor90.42947.154RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
133 TATDN1interactor40.33346.264TatD_DNase (PF01026, IPR001130): TatD related DNase
134 TBC1D22Binteractor40.3338.968RabGAP-TBC (PF00566, IPR000195, SM00164): Rab-GTPase-TBC domain
DUF4502 (PF14950, IPR028026): Domain of unknown function (DUF4502)
135 TCL1Aoncoprotein50.5008.890TCL1_MTCP1 (PF01840, IPR004832): TCL1/MTCP1 family
136 TP53suppressor380.1641286.306DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
137 TRAF4oncoprotein50.16723.052MATH (PF00917, IPR002083, SM00061): MATH domain
Sina (PF03145, IPR018121): Seven in absentia protein family
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger
138 TRIM54interactor170.208300.788DUF349 (PF03993, IPR007139): Domain of Unknown Function (DUF349)
zf-HIT (PF04438, IPR007529): HIT zinc finger
zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
139 TRIM55interactor90.53617.671Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein
NABP (PF07990, IPR012940): Nucleic acid binding protein NABP
zf-HIT (PF04438, IPR007529): HIT zinc finger
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
140 TRIM63interactor120.61824.340DUF349 (PF03993, IPR007139): Domain of Unknown Function (DUF349)
KIP1 (PF07765, IPR011684): KIP1-like protein
RED_C (PF07807, IPR012492): RED-like protein C-terminal region
zf-HIT (PF04438, IPR007529): HIT zinc finger
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
YceG_bac (PF14266, IPR025647): Putative component of 'biosynthetic module'
141 TSEN2interactor21.0000tRNA_int_endo (PF01974, IPR006677): tRNA intron endonuclease, catalytic C-terminal domain
tRNA_int_endo_N (PF02778, IPR006678): tRNA intron endonuclease, N-terminal domain
SLY (PF12485, IPR021090): Lymphocyte signaling adaptor protein
142 TXLNAprotein found in more fusions210.395180.071Taxilin (PF09728, IPR026183): Myosin-like coiled-coil protein
KELK (PF15796, IPR031597): KELK-motif containing domain of MRCK Ser/Thr protein kinase
143 UBASH3Ainteractor40.3336.194His_Phos_1 (PF00300, IPR013078, SM00855): Histidine phosphatase superfamily (branch 1)
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
Ste5 (PF11610, IPR021651): Scaffold protein Ste5-Fus5 binding region
SH3_9 (PF14604, IPR001452): Variant SH3 domain
144 UBCprotein found in more fusions330.198697.971ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
145 UBE2E1protein found in more fusions70.4009.836UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
146 UBE2G1protein found in more fusions302.161UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
147 UBE2Iinteractor210.132524.547UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
148 UNC119interactor50.40015.990GMP_PDE_delta (PF05351, IPR008015): GMP-PDE, delta subunit
149 USP15oncoprotein200.281323.902UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
DUSP (PF06337, IPR006615, SM00695): DUSP domain
Ubiquitin_3 (PF14836, IPR028135): Ubiquitin-like domain
150 USP21interactor100.75014.467UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
151 USP22interactor70.190109.940UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
DUF2769 (PF10967, IPR020075): Protein of unknown function (DUF2769)
152 USP28interactor130.59129.777TPR_3 (PF07720, IPR011716): Tetratricopeptide repeat
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
UBA_4 (PF14555): UBA-like domain
DUF4769 (PF15992, IPR031934): Domain of unknown function (DUF4769)
153 USP4oncoprotein160.257372.762UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
DUSP (PF06337, IPR006615, SM00695): DUSP domain
Ubiquitin_3 (PF14836, IPR028135): Ubiquitin-like domain
154 UTP14Ainteractor70.38139.112Utp14 (PF04615, IPR006709): Utp14 protein
155 VAMP8oncoprotein21.0000Synaptobrevin (PF00957, IPR001388): Synaptobrevin
156 VPS4Binteractor60.40030.524AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
AAA_2 (PF07724, IPR013093): AAA domain (Cdc48 subfamily)
MIT (PF04212, IPR007330, SM00745): MIT (microtubule interacting and transport) domain
MMR_HSR1 (PF01926, IPR006073): 50S ribosome-binding GTPase
TIP49 (PF06068, IPR010339): TIP49 C-terminus
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
157 WWTR1interactor80.5367.481WW (PF00397, IPR001202, SM00456): WW domain
158 YAP1suppressor240.272339.370Bindin (PF02084, IPR000775): Bindin
WW (PF00397, IPR001202, SM00456): WW domain
GspL_C (PF12693, IPR025691): GspL periplasmic domain
FAM181 (PF15238, IPR029359): FAM181
159 YWHABinteractor200.437255.24314-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
Virulence_fact (PF13769, IPR025989): Virulence factor
160 YWHAEoncoprotein220.338465.65414-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
161 YWHAGprotein found in more fusions250.337322.07914-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
162 YWHAHprotein found in more fusions280.330243.61314-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
163 YWHAQinteractor200.411268.20714-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
164 YWHAZprotein found in more fusions240.423263.59214-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
165 ZGPATinteractor40.50010.502Agenet (PF05641, IPR008395, SM00743): Agenet domain
G-patch (PF01585, IPR000467, SM00443): G-patch domain
Laminin_I (PF06008, IPR009254): Laminin Domain I
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167
166 ZNF26interactor100KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain

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