1 |
TCF12 | parental protein | 69 | 0.057 | 3535.995 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain |
2 |
ARMC8 | interactor | 4 | 0.500 | 1.833 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat DUF383 (PF04063, IPR007205): Domain of unknown function (DUF383) HEAT (PF02985, IPR000357): HEAT repeat IFRD (PF05004, IPR007701): Interferon-related developmental regulator (IFRD) Uso1_p115_head (PF04869, IPR006953): Uso1 / p115 like vesicle tethering protein, head region V-ATPase_H_C (PF11698, IPR011987): V-ATPase subunit H UNC45-central (PF11701, IPR024660): Myosin-binding striated muscle assembly central HEAT_EZ (PF13513): HEAT-like repeat |
3 |
ASCL4 | interactor | 2 | 1.000 | 0 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain |
4 |
BMF | suppressor | 1 | 0 | 0 | BMF (PF15185, IPR028192): Bcl-2-modifying factor, apoptosis |
5 |
C16orf45 | interactor | 1 | 0 | 0 | DUF3585 (PF12130, IPR022735): Protein of unknown function (DUF3585) PurL_C (PF16904, IPR031652): Phosphoribosylformylglycinamidine synthase II C-terminus |
6 |
C1orf109 | interactor | 5 | 0.500 | 2.952 | CK2S (PF15011, IPR029159): Casein Kinase 2 substrate |
7 |
CDKN2C | suppressor | 3 | 0.667 | 0.667 | Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies) |
8 |
CFAP206 | interactor | 2 | 0 | 0 | THP2 (PF09432, IPR018557): Tho complex subunit THP2 DUF3508 (PF12018, IPR021897): Domain of unknown function (DUF3508) |
9 |
CRCP | interactor | 4 | 0.500 | 2.167 | RNA_pol_Rpb4 (PF03874, IPR005574): RNA polymerase Rpb4 Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein |
10 |
CREBBP | suppressor | 10 | 0.750 | 3.371 | Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain MAS20 (PF02064, IPR002056): MAS20 protein import receptor TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26 HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) |
11 |
DGCR6 | interactor | 2 | 1.000 | 0 | DGCR6 (PF07324, IPR010849): DiGeorge syndrome critical region 6 (DGCR6) protein |
12 |
EDRF1 | oncoprotein | 1 | 0 | 0 | TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat DUF2315 (PF10231, IPR018796): Uncharacterised conserved protein (DUF2315) |
13 |
ELAVL1 | oncoprotein | 15 | 0.385 | 44.271 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
14 |
EP300 | oncoprotein | 14 | 0.436 | 32.086 | Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type |
15 |
FOXH1 | interactor | 4 | 0.667 | 0.619 | Forkhead (PF00250, IPR001766, SM00339): Forkhead domain |
16 |
FRMD6 | interactor | 1 | 0 | 0 | FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain HTH_24 (PF13412, IPR011991): Winged helix-turn-helix DNA-binding |
17 |
HEXIM2 | interactor | 4 | 0.667 | 0.286 | bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper HEXIM (PF15313, IPR024872): Hexamethylene bis-acetamide-inducible protein GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor |
18 |
HOPX | suppressor | 1 | 0 | 0 | Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
19 |
ID1 | interactor | 3 | 1.000 | 0 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain |
20 |
ID2 | oncoprotein | 4 | 1.000 | 0 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain |
21 |
ID3 | oncoprotein | 4 | 1.000 | 0 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain |
22 |
LYSMD1 | interactor | 1 | 0 | 0 | LysM (PF01476, IPR018392, SM00257): LysM domain |
23 |
MAPKBP1 | interactor | 2 | 1.000 | 0 | eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain WD40_like (PF17005, IPR031544): WD40-like domain |
24 |
MESP2 | interactor | 3 | 1.000 | 0 | DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain |
25 |
MLLT6 | oncoprotein | 3 | 0.667 | 0.400 | DUF572 (PF04502, IPR007590): Family of unknown function (DUF572) HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper SpoIIIAH (PF12685, IPR024232): SpoIIIAH-like protein zf-HC5HC2H (PF13771): PHD-like zinc-binding domain PHD_2 (PF13831): PHD-finger zf-HC5HC2H_2 (PF13832): PHD-zinc-finger like domain SOBP (PF15279, IPR026092): Sine oculis-binding protein SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2 |
26 |
MORN4 | interactor | 2 | 1.000 | 0 | MORN (PF02493, IPR003409, SM00698): MORN repeat |
27 |
MOV10 | interactor | 6 | 0.400 | 6.500 | AAA_12 (PF13087): AAA domain AAA_30 (PF13604): AAA domain |
28 |
MYC | oncoprotein | 12 | 0.545 | 15.919 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region |
29 |
MYF6 | interactor | 2 | 1.000 | 0 | Basic (PF01586, IPR002546, SM00520): Myogenic Basic domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myf5 (PF12232, IPR022032): Myogenic determination factor 5 |
30 |
MYOG | interactor | 3 | 1.000 | 0 | Basic (PF01586, IPR002546, SM00520): Myogenic Basic domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain |
31 |
NAGK | protein found in more fusions | 5 | 0.500 | 2.667 | BcrAD_BadFG (PF01869, IPR002731): BadF/BadG/BcrA/BcrD ATPase family |
32 |
NEUROD1 | interactor | 4 | 1.000 | 0 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain YL1 (PF05764, IPR008895): YL1 nuclear protein Neuro_bHLH (PF12533, IPR022575): Neuronal helix-loop-helix transcription factor |
33 |
NEUROG3 | interactor | 1 | 0 | 0 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Umbravirus_LDM (PF04817, IPR006902): Umbravirus long distance movement (LDM) family |
34 |
NOTCH1 | suppressor | 6 | 0.700 | 2.333 | Ank (PF00023, IPR002110, SM00248): Ankyrin repeat EGF (PF00008, IPR000742, SM00181): EGF-like domain EGF_2 (PF07974, IPR013111): EGF-like domain EGF_alliinase (PF04863, IPR006947): Alliinase EGF-like domain EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain NOD (PF06816, IPR010660): NOTCH protein NODP (PF07684, IPR011656): NOTCH protein TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit Notch (PF00066, IPR000800, SM00004): LNR domain DUF3454 (PF11936, IPR024600): Domain of unknown function (DUF3454) hEGF (PF12661, IPR013032): Human growth factor-like EGF cEGF (PF12662, IPR026823): Complement Clr-like EGF-like Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) |
35 |
NTRK1 | oncoprotein | 12 | 0.382 | 27.638 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
36 |
NXF1 | interactor | 6 | 0.500 | 3.667 | NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain LRR_8 (PF13855, IPR001611): Leucine rich repeat |
37 |
OLIG3 | interactor | 1 | 0 | 0 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain |
38 |
OSGIN1 | suppressor | 3 | 0.667 | 0.667 | Pyr_redox_2 (PF07992, IPR023753): Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 (PF13738): Pyridine nucleotide-disulphide oxidoreductase |
39 |
PRSS23 | interactor | 2 | 1.000 | 0 | Trypsin (PF00089, IPR001254, SM00020): Trypsin |
40 |
PSMA1 | interactor | 5 | 0.833 | 0.500 | Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature |
41 |
QARS | interactor | 4 | 0.667 | 1.167 | tRNA-synt_1c (PF00749, IPR020058): tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C (PF03950, IPR020059): tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 (PF04558, IPR007639): Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_synt_1c_R2 (PF04557, IPR007638): Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 |
42 |
RNASEL | suppressor | 1 | 0 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain Ribonuc_2-5A (PF06479, IPR010513): Ribonuclease 2-5A Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies) |
43 |
RUNX1 | suppressor | 14 | 0.526 | 20.443 | Runt (PF00853, IPR013524): Runt domain RunxI (PF08504, IPR013711): Runx inhibition domain DUF3037 (PF11236, IPR021398): Protein of unknown function (DUF3037) |
44 |
RUNX1T1 | oncoprotein | 7 | 0.733 | 2.667 | NHR2 (PF08788, IPR014896): NHR2 domain like TAFH (PF07531, IPR003894, SM00549): NHR1 homology to TAF zf-MYND (PF01753, IPR002893): MYND finger DUF3731 (PF12531, IPR021030): DNA-K related protein |
45 |
SGF29 | interactor | 2 | 1.000 | 0 | DUF1325 (PF07039, IPR010750): SGF29 tudor-like domain Filament (PF00038, IPR001664): Intermediate filament protein |
46 |
SHMT2 | interactor | 4 | 0.500 | 2.333 | SHMT (PF00464, IPR001085): Serine hydroxymethyltransferase |
47 |
SMAD2 | suppressor | 12 | 0.491 | 21.857 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
48 |
SMAD3 | oncoprotein | 10 | 0.639 | 6.738 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
49 |
SOX2 | oncoprotein | 7 | 0.667 | 3.333 | HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box SOXp (PF12336, IPR022097): SOX transcription factor |
50 |
SPG21 | interactor | 3 | 0.667 | 0.500 | Abhydrolase_1 (PF00561, IPR000073): alpha/beta hydrolase fold |
51 |
SRI | oncoprotein | 3 | 1.000 | 0 | EF-hand_1 (PF00036, IPR002048, SM00054): EF hand EF-hand_7 (PF13499, IPR011992): EF-hand domain pair EF-hand_8 (PF13833, IPR002048): EF-hand domain pair |
52 |
STAT5A | suppressor | 3 | 1.000 | 0 | SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain |
53 |
STK16 | interactor | 4 | 0.667 | 0.667 | Pkinase (PF00069, IPR000719): Protein kinase domain |
54 |
STRN3 | interactor | 4 | 1.000 | 0 | Striatin (PF08232, IPR013258): Striatin family WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
55 |
TAF4 | protein found in more fusions | 4 | 1.000 | 0 | TAF4 (PF05236, IPR007900): Transcription initiation factor TFIID component TAF4 family TAFH (PF07531, IPR003894, SM00549): NHR1 homology to TAF TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) |
56 |
TAL1 | oncoprotein | 7 | 0.867 | 0.619 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain SelK_SelG (PF10961, IPR024491): Selenoprotein SelK_SelG |
57 |
TAL2 | oncoprotein | 3 | 1.000 | 0 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain |
58 |
TBP | interactor | 7 | 0.733 | 2.619 | TBP (PF00352, IPR000814): Transcription factor TFIID (or TATA-binding protein, TBP) EPL1 (PF10513, IPR019542): Enhancer of polycomb-like Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal |
59 |
TCF21 | interactor | 3 | 1.000 | 0 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain |
60 |
TCF23 | interactor | 1 | 0 | 0 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain |
61 |
TCF3 | suppressor | 21 | 0.253 | 110.557 | CDC45 (PF02724, IPR003874): CDC45-like protein HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain DUF3682 (PF12446, IPR022152): Protein of unknown function (DUF3682) |
62 |
TCF4 | suppressor | 31 | 0.103 | 388.586 | CDC45 (PF02724, IPR003874): CDC45-like protein HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain |
63 |
TRIM33 | oncoprotein | 13 | 0.500 | 17.171 | PHD (PF00628, IPR019787, SM00249): PHD-finger Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Siva (PF05458, IPR022773): Cd27 binding protein (Siva) Spectrin (PF00435, IPR002017): Spectrin repeat TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger Bromodomain (PF00439, IPR001487, SM00297): Bromodomain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger |
64 |
TRIM72 | interactor | 1 | 0 | 0 | HrpB7 (PF09486, IPR013392): Bacterial type III secretion protein (HrpB7) IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING |
65 |
TSNAX | interactor | 1 | 0 | 0 | Translin (PF01997, IPR002848): Translin family |
66 |
TWIST2 | suppressor | 2 | 1.000 | 0 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain |
67 |
VPS28 | interactor | 3 | 0.667 | 0.286 | VPS28 (PF03997, IPR007143): VPS28 protein |
68 |
XPO1 | interactor | 12 | 0.348 | 33.919 | CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region |
69 |
ZWINT | interactor | 2 | 0 | 0 | Zwint (PF15556, IPR029092): ZW10 interactor |