Find Fusion Network

Visualization interactions

Powered by Cytoscape Web for: parental proteins SRP14, VPS13B (from a repository: Thu Jul 25 19:44:25 2019)

Examples AFF1 MLL ACTN4 + MLLAFF1 + MLLALK + MSNALK + TFGALK + TPM3ALK + TPM4ASXL2 + KAT6AATF1 + FUSBCR + ABL1BCR + FGFR1CCND1 + TACSTD2CD74 + ROS1CDK6 + MLLCOL1A1 + PDGFBCREB3L2 + PPARGCREB3L2 + FUSCREBBP + KAT6ADAZAP1 + MEF2DELL + MLLEPS15 + MLLERG + EWSR1ERG + FUSERG + TMPRSS2ETV5 + TMPRSS2ETV6 + ABL1ETV6 + NTRK3ETV6 + PAX5EWSR1 + FLI1EWSR1 + WT1FOXO1 + PAX3FOXP1 + PAX5FRYL + MLLGAS7 + MLLGMPS + MLLGOLGA5 + RETHOOK3 + RETHOXC13 + NUP98HOXD13 + NUP98MECOM + RUNX1MKL1 + RBM15MLL + MLLT1MLL + MLLT4MLL + MLLT10MLL + PICALMMLLT10 + PICALMNCOA1 + PAX3NIN + PDGFRBNPM1 + RARANRG1 + ODZ4NTRK1 + TFGNUMA1 + RARANUP98 + PHF23PAX5 + ZNF521PBX1 + TCF3RET + TRIM27ROS1 + SLC34A2PML + RARAPRKAR1A + RARAPRKAR1A + RETRUNX1 + RUNX1T1RUNX1 + SH3D19	Cytoscape Web will replace the contents your graph	PPI Properties: Click on nodes or edges
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Statistics and Network structure information

Statistic of PPI Value(s) The number of interactors (fusion and proteins) 76 The number (and %) of the onco-proteins 16 (21.05 %) The number (and %) of the tumor suppressors 5 (6.58 %) Total number of binary PPIs (saturation %) 459 (16.11 %) The number (and %) of affected PPIs 74 (16.12 %) The number of possible different fusions 12 PPI diameter 5 PPI radius 3 The average degree of PPI 11.526 Assortativity coefficient -0.1844 The network average Clustering coefficient 0.519 The number (and %) of a zero Clustering coefficients 8 (10.53 %) The number (and %) of a zero Betweenness Centrality 12 (15.79 %)

ACTIVE INTERACTORS

List of the fusions
PPI for parental proteins: VPS13B,SRP14	All fusions
Proteins found in more fusions	PRKDC (see 2 fusions); PRPF19 (see 2 fusions); MCM2 (see 1 fusions); DKC1 (see 2 fusions); COPS5 (see 1 fusions); HUWE1 (see 4 fusions); CUL1 (see 3 fusions); CUL3 (see 1 fusions); FN1/RPL6 (see 1 fusions); DDX5 (see 1 fusions); LAMP2 (see 1 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	VPS13B	parental protein	4	0	297.250	ATG_C (PF09333, IPR015412): Autophagy-related protein C terminal domain SHR-BD (PF06650, IPR009543): SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N (PF12624, IPR026854): N-terminal region of Chorein or VPS13 VPS13 (PF16908, IPR031646): Vacuolar sorting-associated protein 13, N-terminal VPS13_C (PF16909, IPR031645): Vacuolar-sorting-associated 13 protein C-terminal
2	SRP14	parental protein	70	0.149	2831.595	SRP14 (PF02290, IPR003210): Signal recognition particle 14kD protein
3	ACIN1	interactor	7	0.714	2.378	Calc_CGRP_IAPP (PF00214, IPR021116): Calcitonin / CGRP / IAPP family CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755) OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAP (PF02037, IPR003034, SM00513): SAP domain V_ATPase_I (PF01496, IPR002490): V-type ATPase 116kDa subunit family FAM27 (PF15832, IPR031672): FAM27 D and E protein family DUF4746 (PF15928, IPR031827): Domain of unknown function (DUF4746) RSB_motif (PF16294, IPR032552): RNSP1-SAP18 binding (RSB) motif SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal
4	ANP32A	suppressor	5	1.000	0	SDA1 (PF05285, IPR007949): SDA1 LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_9 (PF14580): Leucine-rich repeat
5	ASB3	interactor	1	0	0	Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) SOCS_box (PF07525, IPR001496): SOCS box
6	BMI1	oncoprotein	14	0.372	37.977	zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
7	CALM1	interactor	9	0.528	5.292	EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
8	CAND1	interactor	30	0.414	114.601	Adaptin_N (PF01602, IPR002553): Adaptin N terminal region DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981) HEAT (PF02985, IPR000357): HEAT repeat TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20) RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
9	CBS	interactor	7	1.000	0	CBS (PF00571, IPR000644, SM00116): CBS domain DUF1414 (PF07208, IPR009857): Protein of unknown function (DUF1414) PALP (PF00291, IPR001926): Pyridoxal-phosphate dependent enzyme
10	CDC5L	interactor	27	0.378	123.482	OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
11	CLCN2	interactor	1	0	0	CBS (PF00571, IPR000644, SM00116): CBS domain Voltage_CLC (PF00654, IPR001807): Voltage gated chloride channel
12	COPS3	interactor	4	1.000	0	RasGEF (PF00617, IPR001895, SM00147): RasGEF domain TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat PCI (PF01399, IPR000717, SM00088): PCI domain
13	COPS5	protein found in more fusions	23	0.481	50.223	JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
14	CSNK1E	interactor	4	0	93.496	APH (PF01636, IPR002575): Phosphotransferase enzyme family Pkinase (PF00069, IPR000719): Protein kinase domain
15	CUL1	suppressor	21	0.516	34.297	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
16	CUL3	protein found in more fusions	35	0.308	440.085	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
17	DDX5	oncoprotein	23	0.494	58.709	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase P68HR (PF08061, IPR012587): P68HR (NUC004) repeat ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
18	DDX56	interactor	9	0.694	2.943	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
19	DKC1	oncoprotein	13	0.576	13.545	DKCLD (PF08068, IPR012960, SM01136): DKCLD (NUC011) domain PUA (PF01472, IPR002478, SM00359): PUA domain RNA_polI_A34 (PF08208, IPR013240): DNA-directed RNA polymerase I subunit RPA34.5 TruB_N (PF01509, IPR002501): TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 (PF16198, IPR032819): tRNA pseudouridylate synthase B C-terminal domain
20	DNAJC7	interactor	4	0.333	334.897	DnaJ (PF00226, IPR001623, SM00271): DnaJ domain TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat Rapsyn_N (PF10579, IPR019568): Rapsyn N-terminal myristoylation and linker region ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 (PF13414, IPR011990): TPR repeat TPR_17 (PF13431): Tetratricopeptide repeat
21	DPP8	interactor	4	0.833	0.500	DPPIV_N (PF00930, IPR002469): Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S15 (PF02129, IPR000383): X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 (PF00326, IPR001375): Prolyl oligopeptidase family
22	DRICH1	interactor	2	0	53.353	Cwf_Cwc_15 (PF04889, IPR006973): Cwf15/Cwc15 cell cycle control protein DUF2729 (PF10870, IPR022621): Protein of unknown function (DUF2729)
23	EED	suppressor	22	0.414	54.470	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
24	EEF2K	interactor	3	0.667	0.500	Alpha_kinase (PF02816, IPR004166, SM00811): Alpha-kinase family Sel1 (PF08238, IPR006597, SM00671): Sel1 repeat
25	EIF4A3	interactor	26	0.393	122.199	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
26	FAM177A1	interactor	1	0	0	Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Connexin (PF00029, IPR013092, SM00037): Connexin FAM177 (PF14774, IPR028260): FAM177 family
27	FN1	oncoprotein	18	0.405	44.250	fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
28	GAR1	interactor	6	0.667	2.994	Gar1 (PF04410, IPR007504): Gar1/Naf1 RNA binding region
29	HUWE1	oncoprotein	13	0.530	11.427	BUD22 (PF09073, IPR015158): BUD22 DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908) DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Mucin (PF01456, IPR000458): Mucin-like glycoprotein Nop14 (PF04147, IPR007276): Nop14-like family PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32 RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain WWE (PF02825, IPR004170, SM00678): WWE domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)
30	ICAM1	oncoprotein	6	0.600	1.532	Adhes-Ig_like (PF09085, IPR015169): Adhesion molecule, immunoglobulin-like C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain ICAM_N (PF03921, IPR013768): Intercellular adhesion molecule (ICAM), N-terminal domain Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain
31	IGSF8	oncoprotein	8	0.500	3.495	V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain
32	IL7R	interactor	6	0.533	4.200	fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
33	IPO9	interactor	4	0.667	1.333	IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain RIX1 (PF08167, IPR012583): rRNA processing/ribosome biogenesis Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Xpo1 (PF08389, IPR013598): Exportin 1-like protein UNC45-central (PF11701, IPR024660): Myosin-binding striated muscle assembly central HEAT_EZ (PF13513): HEAT-like repeat
34	ITGB1BP2	interactor	2	1.000	0	CHORD (PF04968, IPR007051): CHORD CS (PF04969, IPR007052): CS domain
35	KLC2	interactor	1	0	0	TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat TPR_12 (PF13424): Tetratricopeptide repeat JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II
36	LAMP2	protein found in more fusions	4	1.000	0	Lamp (PF01299, IPR002000): Lysosome-associated membrane glycoprotein (Lamp)
37	LARS	interactor	4	0.500	2.153	Anticodon_1 (PF08264, IPR013155): Anticodon-binding domain of tRNA tRNA-synt_1 (PF00133, IPR002300): tRNA synthetases class I (I, L, M and V)
38	LIN28A	interactor	6	0.533	2.886	CSD (PF00313, IPR002059): 'Cold-shock' DNA-binding domain zf-CCHC (PF00098, IPR001878): Zinc knuckle zf-CCHC_6 (PF15288): Zinc knuckle
39	LYAR	interactor	8	0.821	1.664	DEK_C (PF08766, IPR014876): DEK C terminal domain zf-LYAR (PF08790, IPR014898): LYAR-type C2HC zinc finger DUF3499 (PF12005, IPR021888): Protein of unknown function (DUF3499) U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
40	MCM2	oncoprotein	19	0.320	164.630	AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain
41	METTL18	interactor	6	0.533	3.467	Methyltransf_23 (PF13489): Methyltransferase domain
42	NIFK	interactor	11	0.673	6.763	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) hNIFK_binding (PF12196, IPR021043): FHA Ki67 binding domain of hNIFK
43	NOLC1	interactor	11	0.582	7.130	DTHCT (PF08070, IPR012542): DTHCT (NUC029) region SRP40_C (PF05022, IPR007718): SRP40, C-terminal domain Stm1_N (PF09598, IPR019084): Stm1 stn_TNFRSF12A (PF12191, IPR022316): Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain NST1 (PF13945, IPR025279): Salt tolerance down-regulator SEEEED (PF14797, IPR029394): Serine-rich region of AP3B1, clathrin-adaptor complex DUF4611 (PF15387, IPR027893): Domain of unknown function (DUF4611) PAF (PF15715, IPR031444): PCNA-associated factor IMUP (PF15761, IPR026621): Immortalisation up-regulated protein NuDC (PF16273, IPR032572): Nuclear distribution C domain PHC2_SAM_assoc (PF16616): Unstructured region on Polyhomeotic-like protein 1 and 2
44	NOP56	interactor	17	0.596	20.446	Cytochrom_NNT (PF03264, IPR005126): NapC/NirT cytochrome c family, N-terminal region Nop (PF01798, IPR002687): snoRNA binding domain, fibrillarin NOP5NT (PF08156, IPR012974): NOP5NT (NUC127) domain RNA_polI_A34 (PF08208, IPR013240): DNA-directed RNA polymerase I subunit RPA34.5 SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
45	NPLOC4	interactor	10	0.578	17.673	NPL4 (PF05021, IPR007717): NPL4 family zf-NPL4 (PF05020, IPR007716): NPL4 family, putative zinc binding region UN_NPL4 (PF11543, IPR024682): Nuclear pore localisation protein NPL4
46	P3H1	interactor	7	0.476	12.360	TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat YfiO (PF13525): Outer membrane lipoprotein 2OG-FeII_Oxy_3 (PF13640, IPR005123): 2OG-Fe(II) oxygenase superfamily MCM_N (PF14551, IPR027925): MCM N-terminal domain Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat
47	PAN2	interactor	13	0.372	15.242	RNase_T (PF00929, IPR013520): Exonuclease UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase WD40_like (PF17005, IPR031544): WD40-like domain
48	PDCD2L	interactor	2	1.000	0	PDCD2_C (PF04194, IPR007320): Programmed cell death protein 2, C-terminal putative domain zf-RRN7 (PF11781, IPR021752): Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7
49	PDLIM5	interactor	10	0.622	9.667	LIM (PF00412, IPR001781, SM00132): LIM domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) DUF4749 (PF15936, IPR031847): Domain of unknown function (DUF4749)
50	PHF6	suppressor	6	0.800	1.500	zf-HC5HC2H (PF13771): PHD-like zinc-binding domain YqfQ (PF14181, IPR025571): YqfQ-like protein
51	PKM	oncoprotein	16	0.358	56.935	PK (PF00224, IPR015793): Pyruvate kinase, barrel domain PK_C (PF02887, IPR015795): Pyruvate kinase, alpha/beta domain
52	PLIN3	interactor	12	0.491	21.367	Perilipin (PF03036, IPR004279): Perilipin family
53	POU5F1	oncoprotein	8	0.524	6.629	Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
54	PRKDC	protein found in more fusions	14	0.359	100.721	FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain NUC194 (PF08163, IPR012582): NUC194 domain PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
55	PRPF19	protein found in more fusions	18	0.618	26.650	Prp19 (PF08606, IPR013915): Prp19/Pso4-like WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat U-box (PF04564, IPR003613, SM00504): U-box domain ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
56	RPL10	suppressor	17	0.566	21.990	Ribosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e
57	RPL14	interactor	16	0.625	14.070	KOW (PF00467, IPR005824, SM00739): KOW motif Ribosomal_L14e (PF01929, IPR002784): Ribosomal protein L14 UPF0688 (PF15772, IPR031530): UPF0688 family
58	RPL19	interactor	18	0.556	24.686	DUF1682 (PF07946, IPR012879): Protein of unknown function (DUF1682) Ribosomal_L19e (PF01280, IPR000196): Ribosomal protein L19e
59	RPL6	protein found in more fusions	21	0.452	54.457	Ribosomal_L6e (PF01159, IPR000915): Ribosomal protein L6e Ribosomal_L6e_N (PF03868, IPR005568): Ribosomal protein L6, N-terminal domain
60	RPS4X	interactor	22	0.455	51.791	KOW (PF00467, IPR005824, SM00739): KOW motif Ribosomal_S4e (PF00900, IPR013845): Ribosomal family S4e RS4NT (PF08071, IPR013843): RS4NT (NUC023) domain S4 (PF01479, IPR002942, SM00363): S4 domain 40S_S4_C (PF16121, IPR032277): 40S ribosomal protein S4 C-terminus
61	SAE1	interactor	4	0.833	0.500	ThiF (PF00899, IPR000594): ThiF family
62	SEPT7	interactor	6	0.733	1.888	Fez1 (PF06818): Fez1 Septin (PF00735, IPR000038): Septin
63	SNRPA1	interactor	17	0.426	51.571	LRR_9 (PF14580): Leucine-rich repeat
64	SNRPD1	interactor	18	0.562	25.344	API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5) LSM (PF01423, IPR001163): LSM domain
65	SNRPD2	interactor	18	0.575	27.996	LSM (PF01423, IPR001163): LSM domain
66	SNU13	interactor	17	0.483	33.141	Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
67	SPACA1	interactor	1	0	0	DUF912 (PF06024, IPR009261): Nucleopolyhedrovirus protein of unknown function (DUF912) PRIMA1 (PF16101): Proline-rich membrane anchor 1
68	SRP54	interactor	6	0.700	2.010	5_3_exonuc (PF01367, IPR020045, SM00475): 5'-3' exonuclease, C-terminal SAM fold ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit SRP54 (PF00448, IPR000897, SM00962): SRP54-type protein, GTPase domain SRP54_N (PF02881, IPR013822, SM00963): SRP54-type protein, helical bundle domain SRP_SPB (PF02978, IPR004125): Signal peptide binding domain YlbD_coat (PF14071, IPR025953): Putative coat protein
69	SRP68	interactor	11	0.509	18.519	RhlB (PF12300, IPR022077): ATP-dependent RNA helicase RhlB SRP68 (PF16969, IPR026258): RNA-binding signal recognition particle 68
70	SRP72	interactor	10	0.556	12.599	BTAD (PF03704, IPR005158, SM01043): Bacterial transcriptional activator domain SRP72 (PF08492, IPR013699): SRP72 RNA-binding domain TPR_12 (PF13424): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat SRP_TPR_like (PF17004, IPR031545): Putative TPR-like repeat
71	SRP9	interactor	13	0.218	53.667	SRP9-21 (PF05486): Signal recognition particle 9 kDa protein (SRP9)
72	SRRM2	interactor	17	0.618	21.232	cwf21 (PF08312, IPR013170, SM01115): cwf21 domain DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Pap_E4 (PF02711, IPR003861): E4 protein RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 CTD (PF12815, IPR024945, SM01104): Spt5 C-terminal nonapeptide repeat binding Spt4 DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614)
73	SZRD1	interactor	3	1.000	0	SUZ (PF12752, IPR024771): SUZ domain SUZ-C (PF12901, IPR024642): SUZ-C motif T3SSipB (PF16535, IPR032391): Type III cell invasion protein SipB
74	TRA2A	interactor	13	0.449	177.466	DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RSRP (PF17069): Arginine/Serine-Rich protein 1
75	UBA2	interactor	7	0.810	2.500	ThiF (PF00899, IPR000594): ThiF family UAE_UbL (PF14732, IPR028077): Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA2_C (PF16195, IPR032426): SUMO-activating enzyme subunit 2 C-terminus
76	WDR4	interactor	7	0.429	9.667	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat

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