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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)251
The number (and %) of the onco-proteins81 (32.27 %)
The number (and %) of the tumor suppressors63 (25.10 %)
Total number of binary PPIs (saturation %)2412 (7.69 %)
The number (and %) of affected PPIs256 (10.61 %)
The number of possible different fusions54
PPI diameter4
PPI radius2
The average degree of PPI18.438
Assortativity coefficient-0.1685
The network average Clustering coefficient0.420
The number (and %) of a zero Clustering coefficients12 (4.78 %)
The number (and %) of a zero Betweenness Centrality19 (7.57 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: MAD1L1,SMARCA4 All fusions
Proteins found in more fusions NPM1 (see 1 fusions); HSF1 (see 3 fusions); BCL6 (see 2 fusions); WDR77 (see 1 fusions); RCOR1 (see 2 fusions); PAX6 (see 2 fusions); IKZF1 (see 1 fusions); APC (see 1 fusions); AMOTL2 (see 1 fusions); FANCA (see 1 fusions); SMARCC1 (see 2 fusions); DDX5 (see 1 fusions); STAT1 (see 1 fusions); SNW1 (see 1 fusions); HSPB1/OBSL1 (see 1 fusions); TPM1 (see 2 fusions); PRMT5 (see 2 fusions); NCOA1 (see 2 fusions); USF1 (see 3 fusions); NTRK1/TPM3 (see 3 fusions); STAT3 (see 2 fusions); MAD1L1 (see 3 fusions); TOPBP1 (see 2 fusions); SETD7 (see 2 fusions); MYOD1 (see 1 fusions); HSPB1 (see 4 fusions); POLR2A (see 2 fusions); EPAS1 (see 1 fusions); TSC22D3 (see 2 fusions); PML (see 4 fusions); CHD4 (see 6 fusions); CUL3 (see 1 fusions); SMARCB1 (see 12 fusions); MYC (see 1 fusions); RUNX1 (see 1 fusions); ACTB (see 3 fusions); RXRA (see 2 fusions); COPS5 (see 1 fusions); UBC (see 1 fusions); SS18 (see 1 fusions); TP53 (see 3 fusions); AHR (see 1 fusions); FOXO1 (see 1 fusions); TRIM28 (see 1 fusions); NR3C1 (see 8 fusions); TPM3 (see 2 fusions); CREB1 (see 2 fusions); SP1 (see 1 fusions); CREBBP (see 6 fusions); HNRNPC (see 1 fusions); NTRK1/TPR (see 1 fusions); SMAD3 (see 3 fusions); TRIM29 (see 3 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 MAD1L1parental protein560.0616734.845MAD (PF05557, IPR008672): Mitotic checkpoint protein
Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14
2 SMARCA4parental protein2000.08823130.137DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840)
HSA (PF07529, IPR014012, SM00573): HSA
QLQ (PF08880, IPR014978, SM00951): QLQ
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
BRK (PF07533, IPR006576, SM00592): BRK domain
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
DUF4065 (PF13274, IPR025272): Protein of unknown function (DUF4065)
SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
3 ACTBoncoprotein280.276252.231Actin (PF00022, IPR004000, SM00268): Actin
4 ACTC1interactor50.70010.083Actin (PF00022, IPR004000, SM00268): Actin
5 ACTL6Ainteractor310.437143.826Actin (PF00022, IPR004000, SM00268): Actin
6 ADD1interactor80.57113.758Aldolase_II (PF00596, IPR001303, SM01007): Class II Aldolase and Adducin N-terminal domain
CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
7 ADNPinteractor170.29469.814zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding
PHD_Oberon (PF07227, IPR032881): PHD - plant homeodomain finger protein
E6 (PF00518, IPR001334): Early Protein (E6)
zf-BED (PF02892, IPR003656, SM00614): BED zinc finger
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
8 AHRsuppressor110.6443.411HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
PAS (PF00989, IPR013767, SM00091): PAS fold
PAS_3 (PF08447, IPR013655): PAS fold
PAS_4 (PF08448, IPR013656): PAS fold
9 ALOX5oncoprotein100Lipoxygenase (PF00305, IPR013819): Lipoxygenase
PLAT (PF01477, IPR001024, SM00308): PLAT/LH2 domain
10 AMOTL2protein found in more fusions50.33327.478HOOK (PF05622, IPR008636): HOOK protein
SlyX (PF04102, IPR007236): SlyX
Angiomotin_C (PF12240, IPR024646): Angiomotin C terminal
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
11 ANGPTL4suppressor50.9000.133SlyX (PF04102, IPR007236): SlyX
Fibrinogen_C (PF00147, IPR002181, SM00186): Fibrinogen beta and gamma chains, C-terminal globular domain
12 APCsuppressor100.27853.499APC_15aa (PF05972, IPR009240): APC 15 residue motif
APC_basic (PF05956, IPR009234): APC basic domain
APC_r (PF05923): APC repeat
Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
EB1_binding (PF05937, IPR009232): EB-1 Binding Domain
FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
SAMP (PF05924, IPR009224): SAMP Motif
Suppressor_APC (PF11414, IPR026831): Adenomatous polyposis coli tumour suppressor protein
AIF_C (PF14721, IPR029324): Apoptosis-inducing factor, mitochondrion-associated, C-term
SAS4 (PF15460, IPR029184): Something about silencing, SAS, complex subunit 4
Arm_APC_u3 (PF16629): Armadillo-associated region on APC
APC_u5 (PF16630): Unstructured region on APC between 1st and 2nd catenin-bdg motifs
APC_u9 (PF16633): Unstructured region on APC between 1st two creatine-rich regions
APC_u13 (PF16634): Unstructured region on APC between APC_crr and SAMP
APC_u14 (PF16635): Unstructured region on APC between SAMP and APC_crr
APC_u15 (PF16636): Unstructured region on APC between APC_crr regions 5 and 6
APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain
13 ARoncoprotein400.309244.157Androgen_recep (PF02166, IPR001103): Androgen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
14 ARID1Asuppressor350.418172.163ARID (PF01388, IPR001606, SM00501): ARID/BRIGHT DNA binding domain
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
TAF4 (PF05236, IPR007900): Transcription initiation factor TFIID component TAF4 family
YscJ_FliF_C (PF08345, IPR013556): Flagellar M-ring protein C-terminal
TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence
BAF250_C (PF12031, IPR021906): SWI/SNF-like complex subunit BAF250/Osa
Keratin_2_tail (PF16210, IPR032449): Keratin type II cytoskeletal 1 tail
15 ARID1Boncoprotein230.60139.519ARID (PF01388, IPR001606, SM00501): ARID/BRIGHT DNA binding domain
DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908)
Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
Presenilin (PF01080, IPR001108): Presenilin
DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052)
DUF2235 (PF09994, IPR018712): Uncharacterized alpha/beta hydrolase domain (DUF2235)
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
BAF250_C (PF12031, IPR021906): SWI/SNF-like complex subunit BAF250/Osa
Spt20 (PF12090, IPR021950): Spt20 family
16 ARID2suppressor150.67611.104ARID (PF01388, IPR001606, SM00501): ARID/BRIGHT DNA binding domain
RFX_DNA_binding (PF02257, IPR003150): RFX DNA-binding domain
BAF250_C (PF12031, IPR021906): SWI/SNF-like complex subunit BAF250/Osa
CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain
17 ATF3suppressor170.45026.635bZIP_1 (PF00170, IPR004827): bZIP transcription factor
18 ATL2interactor40.6673.790GBP (PF02263, IPR015894): Guanylate-binding protein, N-terminal domain
GBP_C (PF02841, IPR003191): Guanylate-binding protein, C-terminal domain
19 BAG5interactor40.33312.368BAG (PF02179, IPR003103, SM00264): BAG domain
PDGF_N (PF04692, IPR006782): Platelet-derived growth factor, N terminal region
RRF (PF01765, IPR023584): Ribosome recycling factor
20 BAZ1Binteractor130.39721.574D5_N (PF08706, IPR014818, SM00885): D5 N terminal like
DDT (PF02791, IPR004022, SM00571): DDT domain
DUF106 (PF01956, IPR002809): Integral membrane protein DUF106
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
PHD (PF00628, IPR019787, SM00249): PHD-finger
YL1 (PF05764, IPR008895): YL1 nuclear protein
DDRGK (PF09756, IPR019153, SM01128): DDRGK domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
DUF3635 (PF12330, IPR024604): Domain of unknown function (DUF3635)
Prok-RING_1 (PF14446): Prokaryotic RING finger family 1
FAM176 (PF14851): FAM176 family
WHIM1 (PF15612, IPR028942): WSTF, HB1, Itc1p, MBD9 motif 1
WSD (PF15613, IPR028941): Williams-Beuren syndrome DDT (WSD), D-TOX E motif
21 BCL6oncoprotein210.353106.528BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
DZR (PF12773, IPR025874): Double zinc ribbon
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2HE (PF16278, IPR032566): C2HE / C2H2 / C2HC zinc-binding finger
22 BCL7Asuppressor170.69917.600BCL_N (PF04714, IPR006804): BCL7, N-terminal conserver region
DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
UPF0561 (PF10573, IPR018888): Uncharacterised protein family UPF0561
23 BCL7Bsuppressor140.72523.778BCL_N (PF04714, IPR006804): BCL7, N-terminal conserver region
24 BCL7Csuppressor230.530124.101BCL_N (PF04714, IPR006804): BCL7, N-terminal conserver region
25 BMI1oncoprotein220.39052.563zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
26 BRCA1suppressor530.238859.571BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT
27 BRD4oncoprotein90.30620.290Caldesmon (PF02029, IPR006018): Caldesmon
Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
Stm1_N (PF09598, IPR019084): Stm1
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
NAM-associated (PF14303, IPR029466): No apical meristem-associated C-terminal domain
BET (PF17035, IPR027353): Bromodomain extra-terminal - transcription regulation
BRD4_CDT (PF17105, IPR031354): C-terminal domain of bromodomain protein 4
28 BRD7suppressor180.45176.029HcyBio (PF01837, IPR002708): Homocysteine biosynthesis enzyme, sulfur-incorporation
GntR (PF00392, IPR000524, SM00345): Bacterial regulatory proteins, gntR family
Presenilin (PF01080, IPR001108): Presenilin
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
DUF3512 (PF12024, IPR021900): Domain of unknown function (DUF3512)
MAJIN (PF15077, IPR027816): Membrane-anchored junction protein
29 BRWD1interactor40.8330.406WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
SEEEED (PF14797, IPR029394): Serine-rich region of AP3B1, clathrin-adaptor complex
30 BYSLinteractor70.38134.409Bystin (PF05291, IPR007955): Bystin
MEA1 (PF06910, IPR009685): Male enhanced antigen 1 (MEA1)
31 CADoncoprotein130.308120.679Amidohydro_1 (PF01979, IPR006680): Amidohydrolase family
CPSase_L_D2 (PF02786, IPR005479): Carbamoyl-phosphate synthase L chain, ATP binding domain
CPSase_L_D3 (PF02787, IPR005480, SM01096): Carbamoyl-phosphate synthetase large chain, oligomerisation domain
CPSase_sm_chain (PF00988, IPR002474, SM01097): Carbamoyl-phosphate synthase small chain, CPSase domain
GATase (PF00117, IPR017926): Glutamine amidotransferase class-I
MGS (PF02142, IPR011607, SM00851): MGS-like domain
OTCace (PF00185, IPR006131): Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain
OTCace_N (PF02729, IPR006132): Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain
ATPgrasp_Ter (PF15632, IPR011226): ATP-grasp in the biosynthetic pathway with Ter operon
32 CAND1interactor320.340146.732Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981)
HEAT (PF02985, IPR000357): HEAT repeat
TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20)
RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
33 CARM1oncoprotein250.347291.186K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
PRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase
CBP_GIL (PF10995, IPR017745): GGDEF I-site like or GIL domain
CARM1 (PF11531, IPR020989): Coactivator-associated arginine methyltransferase 1 N terminal
34 CATsuppressor40.6670.168Catalase (PF00199, IPR011614, SM01060): Catalase
Catalase-rel (PF06628, IPR010582): Catalase-related immune-responsive
35 CBX5suppressor200.281219.085Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
Chromo_shadow (PF01393, IPR008251, SM00300): Chromo shadow domain
36 CCDC94interactor31.0000DUF572 (PF04502, IPR007590): Family of unknown function (DUF572)
37 CCHCR1interactor70.46711.902HCR (PF07111, IPR009800): Alpha helical coiled-coil rod protein (HCR)
38 CCNE1oncoprotein140.41884.186Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
39 CDC20oncoprotein180.257213.332WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
40 CDC27oncoprotein210.226285.525TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
41 CDC5Linteractor440.2271411.091OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component
Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
42 CDK19interactor80.6078.149Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
Pkinase (PF00069, IPR000719): Protein kinase domain
43 CDK8interactor250.42084.629Pkinase (PF00069, IPR000719): Protein kinase domain
44 CDKN2Asuppressor210.41985.309Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
45 CDX2suppressor60.5336.333CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Caudal_act (PF04731, IPR006820): Caudal like protein activation region
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
46 CDYLinteractor80.7502.165Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
ECH_1 (PF00378, IPR001753): Enoyl-CoA hydratase/isomerase
ECH_2 (PF16113, IPR032259): Enoyl-CoA hydratase/isomerase
47 CEBPAsuppressor150.56038.142Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
DUF2514 (PF10721, IPR019659): Protein of unknown function (DUF2514)
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
48 CEBPBoncoprotein300.42982.836RhlB (PF12300, IPR022077): ATP-dependent RNA helicase RhlB
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
49 CHD4oncoprotein370.268381.267CDC27 (PF09507, IPR019038): DNA polymerase subunit Cdc27
CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain
CHDNT (PF08073, IPR012958): CHDNT (NUC034) domain
Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
DTHCT (PF08070, IPR012542): DTHCT (NUC029) region
DUF1086 (PF06461, IPR009462, SM01146): Domain of Unknown Function (DUF1086)
DUF1087 (PF06465, IPR009463, SM01147): Domain of Unknown Function (DUF1087)
PHD (PF00628, IPR019787, SM00249): PHD-finger
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
FAM176 (PF14851): FAM176 family
Coilin_N (PF15862, IPR031722): Coilin N-terminus
50 CHD7interactor100.7336.580CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain
Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
BRK (PF07533, IPR006576, SM00592): BRK domain
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
DUF3484 (PF11983, IPR021873): Membrane-attachment and polymerisation-promoting switch
SpoIIIAH (PF12685, IPR024232): SpoIIIAH-like protein
Myb_DNA-bind_7 (PF15963): Myb DNA-binding like
51 CHFRsuppressor100.55634.965FHA (PF00498, IPR000253, SM00240): FHA domain
Glyco_hydro_92 (PF07971, IPR012939): Glycosyl hydrolase family 92
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
LAX (PF15681, IPR031393): Lymphocyte activation family X
52 CHMP5interactor200Snf7 (PF03357, IPR005024): Snf7
53 CIITAoncoprotein80.5005.124NACHT (PF05729): NACHT domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
54 CLEC11Ainteractor100ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
HBS1_N (PF08938, IPR015033): HBS1 N-terminus
Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain
55 COILinteractor90.14377.571CDC45 (PF02724, IPR003874): CDC45-like protein
Macoilin (PF09726, IPR019130): Transmembrane protein
Coilin_N (PF15862, IPR031722): Coilin N-terminus
56 COPS5protein found in more fusions440.243464.624JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
57 CPSF2interactor140.40728.697RMMBL (PF07521, IPR011108): Zn-dependent metallo-hydrolase RNA specificity domain
Beta-Casp (PF10996, IPR022712, SM01027): Beta-Casp domain
CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal
Lactamase_B_6 (PF16661, IPR001279): Metallo-beta-lactamase superfamily domain
58 CREB1oncoprotein190.45840.394bZIP_1 (PF00170, IPR004827): bZIP transcription factor
pKID (PF02173, IPR003102): pKID domain
DUF4988 (PF16378, IPR032149): Domain of unknown function
59 CREBBPsuppressor650.2221013.550Creb_binding (PF09030, IPR014744): Creb binding
DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902)
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
KIX (PF02172, IPR003101): KIX domain
MAS20 (PF02064, IPR002056): MAS20 protein import receptor
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger
ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26
HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729)
DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
60 CTNNB1oncoprotein310.305215.207Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361)
HEAT_EZ (PF13513): HEAT-like repeat
61 CUL3protein found in more fusions560.199982.961Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
62 CWF19L2interactor30.3335.687CwfJ_C_1 (PF04677, IPR006768): Protein similar to CwfJ C-terminus 1
CwfJ_C_2 (PF04676, IPR006767): Protein similar to CwfJ C-terminus 2
DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755)
Pap_E4 (PF02711, IPR003861): E4 protein
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
DUF4519 (PF15012, IPR027960): Domain of unknown function (DUF4519)
MRI (PF15325, IPR028278): Modulator of retrovirus infection
63 DDX5oncoprotein290.336236.736DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
P68HR (PF08061, IPR012587): P68HR (NUC004) repeat
ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
64 DPF1interactor71.0000PHD (PF00628, IPR019787, SM00249): PHD-finger
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
Requiem_N (PF14051, IPR025750): N-terminal domain of DPF2/REQ.
PHD_4 (PF16866, IPR019787): PHD-finger
65 DPF2interactor230.61732.704PHD (PF00628, IPR019787, SM00249): PHD-finger
zf-C2H2_4 (PF13894): C2H2-type zinc finger
Requiem_N (PF14051, IPR025750): N-terminal domain of DPF2/REQ.
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
Zf_RING (PF16744, IPR031946): KIAA1045 RING finger
66 DPF3interactor210.67133.113PHD (PF00628, IPR019787, SM00249): PHD-finger
zf-C2H2_4 (PF13894): C2H2-type zinc finger
Requiem_N (PF14051, IPR025750): N-terminal domain of DPF2/REQ.
Lar_restr_allev (PF14354): Restriction alleviation protein Lar
67 EEDsuppressor390.257251.772WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
68 EP400oncoprotein110.5828.469FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
DDHD (PF02862, IPR004177, SM01127): DDHD domain
GN3L_Grn1 (PF08701, IPR014813): GNL3L/Grn1 putative GTPase
HSA (PF07529, IPR014012, SM00573): HSA
Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
EPL1 (PF10513, IPR019542): Enhancer of polycomb-like
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
DUF3304 (PF11745, IPR021733): Protein of unknown function (DUF3304)
DUF3381 (PF11861, IPR024576): Domain of unknown function (DUF3381)
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
DUF3484 (PF11983, IPR021873): Membrane-attachment and polymerisation-promoting switch
DUF3573 (PF12097, IPR021956): Protein of unknown function (DUF3573)
Myb_DNA-bind_4 (PF13837): Myb/SANT-like DNA-binding domain
EP400_N (PF15790, IPR031575): E1A-binding protein p400, N-terminal
69 EPAS1suppressor220.348104.483Corona_I (PF03187, IPR004876): Corona nucleocapsid I protein
HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
PAS (PF00989, IPR013767, SM00091): PAS fold
HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1
PAS_11 (PF14598): PAS domain
70 ESR1suppressor640.211936.062Oest_recep (PF02159, IPR001292): Oestrogen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
71 FAM131Cinteractor203.717FAM131 (PF15010, IPR026782): Putative cell signalling
72 FANCAoncoprotein70.4673.989Fanconi_A (PF03511, IPR003516): Fanconi anaemia group A protein
Fanconi_A_N (PF15865, IPR031729): Fanconi anaemia group A protein N terminus
73 FBXO6interactor180.17092.841FBA (PF04300, IPR007397): F-box associated region
F-box-like (PF12937, IPR001810): F-box-like
74 FLNBoncoprotein90.22260.401CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
Filamin (PF00630, IPR017868): Filamin/ABP280 repeat
PapC_N (PF13954, IPR025885): PapC N-terminal domain
75 FOXE1oncoprotein90.25024.401Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
76 FOXJ2interactor100.22284.461SARAF (PF06682, IPR009567): SOCE-associated regulatory factor of calcium homoeostasis
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
Spt20 (PF12090, IPR021950): Spt20 family
Pro-rich (PF15240, IPR026086): Proline-rich
77 FOXO1suppressor120.6554.265K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
FOXO_KIX_bdg (PF16675, IPR032068): KIX-binding domain of forkhead box O, CR2
FOXO-TAD (PF16676, IPR032067): Transactivation domain of FOXO protein family
78 GATA1oncoprotein160.425129.370GATA (PF00320, IPR000679, SM00401): GATA zinc finger
Vps36-NZF-N (PF16988, IPR031558): Vacuolar protein sorting 36 NZF-N zinc-finger domain
79 GLI1suppressor80.8210.877zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain
80 GMNNinteractor50.3008.059Geminin (PF07412, IPR022786): Geminin
81 GTF3C3interactor150.33371.848BUD22 (PF09073, IPR015158): BUD22
PGA2 (PF07543, IPR011431): Protein trafficking PGA2
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
Foie-gras_1 (PF11817, IPR021773): Foie gras liver health family 1
DUF3369 (PF11849, IPR021800): Domain of unknown function (DUF3369)
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
TPR_20 (PF14561): Tetratricopeptide repeat
82 H2AFXsuppressor250.290136.088Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
83 HAUS1interactor70.46736.241THP2 (PF09432, IPR018557): Tho complex subunit THP2
XhlA (PF10779, IPR019715): Haemolysin XhlA
DUF3496 (PF12001, IPR021885): Domain of unknown function (DUF3496)
84 HDAC1suppressor840.1982352.938FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
85 HDAC2suppressor700.2081708.932Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
86 HDAC3suppressor380.242310.265Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
87 HDAC9interactor150.374130.186Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
SAE2 (PF08573, IPR013882): DNA repair protein endonuclease SAE2/CtIP C-terminus
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
CEP19 (PF14933, IPR029412): CEP19-like protein
88 HIF1Asuppressor260.49255.824Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein
HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
PAS (PF00989, IPR013767, SM00091): PAS fold
PAS_3 (PF08447, IPR013655): PAS fold
HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1
89 HIST1H3Ainteractor300.273174.390Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
90 HIST1H3Einteractor220.32087.512Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
91 HIST1H4Finteractor70.38154.318CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold
92 HIST2H2BEinteractor190.34596.783Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
93 HIST2H3Cinteractor120.21261.720Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
94 HMGB1oncoprotein110.6008.021HMG_box_2 (PF09011, IPR009071): HMG-box domain
NOA36 (PF06524, IPR010531): NOA36 protein
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
95 HNRNPCprotein found in more fusions250.38869.476APG6 (PF04111, IPR007243): Autophagy protein Apg6
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SURF2 (PF05477, IPR008833): Surfeit locus protein 2 (SURF2)
96 HSF1protein found in more fusions120.41864.967DUF247 (PF03140, IPR004158): Plant protein of unknown function
Vert_HS_TF (PF06546, IPR010542): Vertebrate heat shock transcription factor
HSF_DNA-bind (PF00447, IPR000232, SM00415): HSF-type DNA-binding
97 HSF4interactor30.6670.400Vert_HS_TF (PF06546, IPR010542): Vertebrate heat shock transcription factor
HSF_DNA-bind (PF00447, IPR000232, SM00415): HSF-type DNA-binding
98 HSP90B1suppressor190.36378.273CobT (PF06213, IPR006538): Cobalamin biosynthesis protein CobT
HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
Sigma70_ner (PF04546, IPR007631): Sigma-70, non-essential region
99 HSPB1oncoprotein270.246519.688HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
100 IKZF1suppressor170.43389.794Desulfoferrod_N (PF06397, IPR004462): Desulfoferrodoxin, N-terminal domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-met (PF12874): Zinc-finger of C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
101 IKZF3suppressor100.50033.817C1_2 (PF03107, IPR004146): C1 domain
Desulfoferrod_N (PF06397, IPR004462): Desulfoferrodoxin, N-terminal domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
zf-C2H2_7 (PF15269): Zinc-finger
102 ING1suppressor190.50330.362PHD (PF00628, IPR019787, SM00249): PHD-finger
NPR3 (PF03666, IPR005365): Nitrogen Permease regulator of amino acid transport activity 3
ING (PF12998, IPR024610): Inhibitor of growth proteins N-terminal histone-binding
zf-C4pol (PF14260, IPR025687): C4-type zinc-finger of DNA polymerase delta
103 IRF1suppressor70.7621.133IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor
104 JUNBoncoprotein80.50019.406bZIP_1 (PF00170, IPR004827): bZIP transcription factor
Jun (PF03957, IPR005643): Jun-like transcription factor
105 KCNAB3interactor100Aldo_ket_red (PF00248, IPR023210): Aldo/keto reductase family
106 KDM6Asuppressor70.33317.707JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat
TPR_17 (PF13431): Tetratricopeptide repeat
107 KLF1interactor110.6556.186zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
EKLF_TAD1 (PF16832, IPR031786): Erythroid krueppel-like transcription factor, transactivation 1
EKLF_TAD2 (PF16833, IPR031784): Erythroid krueppel-like transcription factor, transactivation 2
108 KLF4suppressor70.7143.333zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
109 KPNA1interactor200.33276.471Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
IBB (PF01749, IPR002652): Importin beta binding domain
Arm_3 (PF16186, IPR032413): Atypical Arm repeat
110 KPNA2interactor200.36387.571Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
IBB (PF01749, IPR002652): Importin beta binding domain
Arm_3 (PF16186, IPR032413): Atypical Arm repeat
111 LGALSLinteractor100Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin
112 LMNB1interactor100.244243.128Filament (PF00038, IPR001664): Intermediate filament protein
LTD (PF00932, IPR001322): Lamin Tail Domain
113 MAD2L1oncoprotein150.187143.091HORMA (PF02301, IPR003511): HORMA domain
114 MAD2L1BPinteractor70.60012.792p31comet (PF06581, IPR009511): Mad1 and Cdc20-bound-Mad2 binding
115 MAML1interactor70.4296.494MamL-1 (PF09596, IPR019082): MamL-1 domain
Kri1 (PF05178, IPR018034): KRI1-like family
PRIMA1 (PF16101): Proline-rich membrane anchor 1
116 MARK4oncoprotein40.5004.406KA1 (PF02149, IPR001772): Kinase associated domain 1
Pkinase (PF00069, IPR000719): Protein kinase domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
117 MBD3interactor150.51618.959DUF2201_N (PF13203, IPR025154): Putative metallopeptidase domain
118 MCPH1suppressor90.52811.011BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
MSP (PF01716, IPR002628): Manganese-stabilising protein / photosystem II polypeptide
Spectrin (PF00435, IPR002017): Spectrin repeat
Microcephalin (PF12258, IPR022047): Microcephalin protein
PTCB-BRCT (PF12738, IPR001357): twin BRCT domain
BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
119 MDC1suppressor280.257293.683FHA (PF00498, IPR000253, SM00240): FHA domain
DUF3274 (PF11678, IPR021692): Protein of unknown function (DUF3274)
Yop-YscD_cpl (PF16697, IPR032030): Inner membrane component of T3SS, cytoplasmic domain
RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
120 MDM2oncoprotein370.284353.701Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region
Presenilin (PF01080, IPR001108): Presenilin
SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain
zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
121 MED17oncoprotein150.27684.314Med17 (PF10156, IPR019313): Subunit 17 of Mediator complex
122 MED6interactor80.7143.653Med6 (PF04934, IPR007018): MED6 mediator sub complex component
Peptidase_M15 (PF01427, IPR000755): D-ala-D-ala dipeptidase
123 METTL21Cinteractor30.33313.449Methyltransf_16 (PF10294, IPR019410): Lysine methyltransferase
124 MFAP1interactor80.39345.750MFAP1 (PF06991, IPR009730): Microfibril-associated/Pre-mRNA processing
DUF3464 (PF11947, IPR021855): Protein of unknown function (DUF3464)
SIR4_SID (PF16991, IPR031556): Sir4 SID domain
125 MKL1oncoprotein50.7002.465RPEL (PF02755, IPR004018, SM00707): RPEL repeat
SAP (PF02037, IPR003034, SM00513): SAP domain
Troponin-I_N (PF11636, IPR021666): Troponin I residues 1-32
126 MNTsuppressor60.60014.858HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Sipho_Gp157 (PF05565, IPR008840): Siphovirus Gp157
DUF4337 (PF14235, IPR025570): Domain of unknown function (DUF4337)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
127 MPP6interactor21.0000L27 (PF02828, IPR014775, SM00569): L27 domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
SH3_2 (PF07653, IPR011511): Variant SH3 domain
Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase
128 MYConcoprotein550.2271133.824HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain
Myc_N (PF01056, IPR012682): Myc amino-terminal region
129 MYEF2interactor100.311134.961RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
130 MYO18Ainteractor60.20040.639Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
131 MYOCDinteractor60.5333.552BES1_N (PF05687, IPR008540): BES1/BZR1 plant transcription factor, N-terminal
IncA (PF04156, IPR007285): IncA protein
RPEL (PF02755, IPR004018, SM00707): RPEL repeat
SAP (PF02037, IPR003034, SM00513): SAP domain
Totivirus_coat (PF05518, IPR008871): Totivirus coat protein
132 MYOD1oncoprotein240.296127.130Basic (PF01586, IPR002546, SM00520): Myogenic Basic domain
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Mfp-3 (PF04202, IPR007328): Foot protein 3
Myf5 (PF12232, IPR022032): Myogenic determination factor 5
133 MYOGinteractor50.5002.745Basic (PF01586, IPR002546, SM00520): Myogenic Basic domain
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
134 NCOA1oncoprotein260.363109.251DUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518)
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Nuc_rec_co-act (PF08815, IPR014920): Nuclear receptor coactivator
PAS (PF00989, IPR013767, SM00091): PAS fold
PAS_3 (PF08447, IPR013655): PAS fold
SRC-1 (PF08832, IPR014935): Steroid receptor coactivator
PAS_11 (PF14598): PAS domain
DUF4927 (PF16279, IPR032565): Domain of unknown function (DUF4927)
NCOA_u2 (PF16665): Unstructured region on nuclear receptor coactivator protein
135 NCOR1oncoprotein380.329289.403BES1_N (PF05687, IPR008540): BES1/BZR1 plant transcription factor, N-terminal
Lamp (PF01299, IPR002000): Lysosome-associated membrane glycoprotein (Lamp)
MAS20 (PF02064, IPR002056): MAS20 protein import receptor
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein
Hid1 (PF12722): High-temperature-induced dauer-formation protein
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain
DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
RBR (PF17208): RNA binding Region
136 NCOR2oncoprotein260.406133.111CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
MAS20 (PF02064, IPR002056): MAS20 protein import receptor
OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain
PSK (PF06404, IPR009438): Phytosulfokine precursor protein (PSK)
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
Gti1_Pac2 (PF09729, IPR018608): Gti1/Pac2 family
PRCC (PF10253, IPR018800): Mitotic checkpoint regulator, MAD2B-interacting
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
Spt20 (PF12090, IPR021950): Spt20 family
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
DUF4518 (PF15008, IPR026698): Domain of unknown function (DUF4518)
GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain
DUF4820 (PF16091, IPR032150): Domain of unknown function (DUF4820)
137 NEBLinteractor100Bac_small_YrzI (PF09501, IPR012655): Probable sporulation protein (Bac_small_yrzI)
Annexin (PF00191, IPR018502, SM00335): Annexin
Nebulin (PF00880, IPR000900, SM00227): Nebulin repeat
SH3_9 (PF14604, IPR001452): Variant SH3 domain
138 NEIL3interactor30.6670.396Fapy_DNA_glyco (PF01149, IPR012319, SM00898): Formamidopyrimidine-DNA glycosylase N-terminal domain
H2TH (PF06831, IPR015886): Formamidopyrimidine-DNA glycosylase H2TH domain
zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS
zf-GRF (PF06839, IPR010666): GRF zinc finger
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
139 NEUROD1interactor21.0000HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
YL1 (PF05764, IPR008895): YL1 nuclear protein
Neuro_bHLH (PF12533, IPR022575): Neuronal helix-loop-helix transcription factor
140 NEUROG2interactor21.0000Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Pacs-1 (PF10254, IPR019381): PACS-1 cytosolic sorting protein
141 NF1suppressor40.6670.776MIF4G_like_2 (PF09090, IPR015174): MIF4G like
RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase
CRAL_TRIO_2 (PF13716, IPR001251): Divergent CRAL/TRIO domain
MOR2-PAG1_C (PF14225, IPR025481): Cell morphogenesis C-terminal
142 NFATC1oncoprotein150.41028.540RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
143 NFE2L2oncoprotein130.53817.121bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor
144 NINLinteractor120.197196.025PD40 (PF07676, IPR011659): WD40-like Beta Propeller Repeat
TBCA (PF02970, IPR004226): Tubulin binding cofactor A
DUF2389 (PF09493, IPR012663): Tryptophan-rich protein (DUF2389)
Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5
EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein
FAM184 (PF15665): Family with sequence similarity 184, A and B
TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain
145 NONOoncoprotein280.385266.473GvpL_GvpF (PF06386, IPR009430): Gas vesicle synthesis protein GvpL/GvpF
NOPS (PF08075, IPR012975): NOPS (NUC059) domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PAS_7 (PF12860): PAS fold
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
146 NOP56interactor150.36226.644Cytochrom_NNT (PF03264, IPR005126): NapC/NirT cytochrome c family, N-terminal region
Nop (PF01798, IPR002687): snoRNA binding domain, fibrillarin
NOP5NT (PF08156, IPR012974): NOP5NT (NUC127) domain
RNA_polI_A34 (PF08208, IPR013240): DNA-directed RNA polymerase I subunit RPA34.5
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
147 NOTCH1suppressor250.290142.468Ank (PF00023, IPR002110, SM00248): Ankyrin repeat
EGF (PF00008, IPR000742, SM00181): EGF-like domain
EGF_2 (PF07974, IPR013111): EGF-like domain
EGF_alliinase (PF04863, IPR006947): Alliinase EGF-like domain
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
NOD (PF06816, IPR010660): NOTCH protein
NODP (PF07684, IPR011656): NOTCH protein
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
Notch (PF00066, IPR000800, SM00004): LNR domain
DUF3454 (PF11936, IPR024600): Domain of unknown function (DUF3454)
hEGF (PF12661, IPR013032): Human growth factor-like EGF
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
148 NPM1suppressor430.253524.187Nucleoplasmin (PF03066): Nucleoplasmin
SDA1 (PF05285, IPR007949): SDA1
NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain
149 NR1H2oncoprotein60.6007.857zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
150 NR2C1interactor140.6048.639zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
DUF2318 (PF10080, IPR018758): Predicted membrane protein (DUF2318)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
151 NR3C1protein found in more fusions260.430103.981GCR (PF02155, IPR001409): Glucocorticoid receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
152 NR4A2oncoprotein90.44410.007zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
153 NRDCinteractor80.23861.267Cnd2 (PF05786, IPR022816): Condensin complex subunit 2
Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16)
Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain
Tom22 (PF04281, IPR005683): Mitochondrial import receptor subunit Tom22
Peptidase_M16_M (PF16187, IPR032632): Middle or third domain of peptidase_M16
154 NTRK1oncoprotein720.1462966.840I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
155 NUDCinteractor41.0000CS (PF04969, IPR007052): CS domain
D5_N (PF08706, IPR014818, SM00885): D5 N terminal like
Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
Nudc_N (PF14050, IPR025934): N-terminal conserved domain of Nudc.
NuDC (PF16273, IPR032572): Nuclear distribution C domain
156 OBSL1protein found in more fusions410.169545.261BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
157 PABPN1interactor110.54510.848RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain
Shadoo (PF14999, IPR029238): Shadow of prion protein, neuroprotective
158 PAPD5interactor40.5002.574NTP_transf_2 (PF01909, IPR002934): Nucleotidyltransferase domain
PAP_assoc (PF03828, IPR002058): Cid1 family poly A polymerase
Pheromone (PF08015, IPR012597): Fungal mating-type pheromone
Secretin_N_2 (PF07655, IPR011514): Secretin N-terminal domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
159 PARD6Ainteractor30.6671.059PB1 (PF00564, IPR000270, SM00666): PB1 domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
160 PAX6suppressor60.6002.801PAX (PF00292, IPR001523, SM00351): 'Paired box' domain
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
161 PBRM1suppressor230.37998.128BAH (PF01426, IPR001025, SM00439): BAH domain
BRF1 (PF07741, IPR011665): Brf1-like TBP-binding domain
CHDNT (PF08073, IPR012958): CHDNT (NUC034) domain
Sporozoite_P67 (PF05642, IPR008845): Sporozoite P67 surface antigen
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
DUF3504 (PF12012, IPR021893): Domain of unknown function (DUF3504)
162 PBX1oncoprotein110.38217.775PBC (PF03792, IPR005542): PBC domain
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
163 PELOinteractor70.6193.028eRF1_1 (PF03463, IPR005140): eRF1 domain 1
eRF1_2 (PF03464, IPR005141): eRF1 domain 2
eRF1_3 (PF03465, IPR005142): eRF1 domain 3
164 PHBsuppressor240.33390.975Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family
DUF4290 (PF14123, IPR025632): Domain of unknown function (DUF4290)
165 PHF10interactor100.9110.780Herpes_MCP (PF03122, IPR000912): Herpes virus major capsid protein
PHD (PF00628, IPR019787, SM00249): PHD-finger
MRI (PF15325, IPR028278): Modulator of retrovirus infection
166 PMLsuppressor390.314241.255zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
DUF3583 (PF12126, IPR021978): Protein of unknown function (DUF3583)
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
167 PMS2oncoprotein60.46718.901DNA_mis_repair (PF01119, IPR013507): DNA mismatch repair protein, C-terminal domain
MORN_2 (PF07661, IPR011652): MORN repeat variant
MutL_C (PF08676, IPR014790, SM00853): MutL C terminal dimerisation domain
HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
168 POLR2Aprotein found in more fusions290.278141.303RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1
RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2
RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3
RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4
RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5
RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat
169 POLR3Ainteractor80.50032.907RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1
RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2
RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3
RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4
RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5
170 POLR3Cinteractor40.8330.833HTH_9 (PF08221, IPR013197): RNA polymerase III subunit RPC82 helix-turn-helix domain
NIT (PF08376, IPR013587): Nitrate and nitrite sensing
RNA_pol_Rpc82 (PF05645, IPR008806): RNA polymerase III subunit RPC82
HD_4 (PF13328, IPR003607): HD domain
171 POLR3Finteractor31.0000RNA_pol_Rpc34 (PF05158, IPR007832): RNA polymerase Rpc34 subunit
172 PPARGsuppressor260.38390.086zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
PPARgamma_N (PF12577, IPR022590): PPAR gamma N-terminal region
173 PRMT5protein found in more fusions230.333106.224PRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase
174 PSMA1interactor90.28646.039Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
175 RAB5Concoprotein60.6672.776Ras (PF00071, IPR001806, SM00173): Ras family
176 RB1suppressor300.340169.721RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain
RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain
Rb_C (PF08934, IPR015030): Rb C-terminal domain
DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452)
DUF4592 (PF15262, IPR028030): Domain of unknown function (DUF4592)
177 RBBP4oncoprotein390.294290.535eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein
CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
178 RBL1suppressor140.53815.288RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain
RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain
Rb_C (PF08934, IPR015030): Rb C-terminal domain
DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452)
179 RBL2suppressor90.5005.790CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Pap_E4 (PF02711, IPR003861): E4 protein
RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain
RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain
SLH (PF00395, IPR001119): S-layer homology domain
TFIIB (PF00382, IPR013150): Transcription factor TFIIB repeat
DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452)
180 RBPJinteractor160.30089.000BTD (PF09270, IPR015350): Beta-trefoil DNA-binding domain
LAG1-DNAbind (PF09271, IPR015351): LAG1, DNA binding
TIG (PF01833, IPR002909): IPT/TIG domain
181 RCOR1protein found in more fusions120.52727.891DivIC (PF04977, IPR007060): Septum formation initiator
ELM2 (PF01448, IPR000949): ELM2 domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
FAM76 (PF16046, IPR032017): FAM76 protein
182 REEP5interactor30.6670.500Phage_holin_3_6 (PF07332, IPR009937): Putative Actinobacterial Holin-X, holin superfamily III
TB2_DP1_HVA22 (PF03134, IPR004345): TB2/DP1, HVA22 family
183 RELBoncoprotein90.7782.107RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
RelB_leu_zip (PF16180, IPR032399): RelB leucine zipper
RelB_transactiv (PF16181, IPR032400): RelB transactivation domain
184 RESToncoprotein130.56416.488CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
Presenilin (PF01080, IPR001108): Presenilin
RNA_POL_M_15KD (PF02150, IPR001529): RNA polymerases M/15 Kd subunit
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
DNA_RNApol_7kD (PF03604, IPR006591, SM00659): DNA directed RNA polymerase, 7 kDa subunit
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain
SLBP_RNA_bind (PF15247, IPR029344): Histone RNA hairpin-binding protein RNA-binding domain
185 RNF2interactor400.233533.875zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
186 RNF8suppressor100.27876.398FHA (PF00498, IPR000253, SM00240): FHA domain
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
DUF4665 (PF15679, IPR031389): Domain of unknown function (DUF4665)
187 RPS6KA5interactor80.4646.885Choline_kinase (PF01633): Choline/ethanolamine kinase
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
188 RUNX1suppressor190.55618.911Runt (PF00853, IPR013524): Runt domain
RunxI (PF08504, IPR013711): Runx inhibition domain
DUF3037 (PF11236, IPR021398): Protein of unknown function (DUF3037)
189 RXRAoncoprotein200.36399.414zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
Nuc_recep-AF1 (PF11825, IPR021780): Nuclear/hormone receptor activator site AF-1
190 SCARA3interactor100Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
Filament (PF00038, IPR001664): Intermediate filament protein
Flagellin_C (PF00700, IPR001029): Bacterial flagellin C-terminal helical region
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
zf-C2H2_10 (PF16588, IPR001878): C2H2 zinc-finger
191 SCARNA22interactor120.25822.091NA
192 SENP3interactor160.367175.516Nop53 (PF07767, IPR011687): Nop53 (60S ribosomal biogenesis)
Peptidase_C48 (PF02902, IPR003653): Ulp1 protease family, C-terminal catalytic domain
193 SETD7protein found in more fusions120.43615.936MORN (PF02493, IPR003409, SM00698): MORN repeat
MORN_2 (PF07661, IPR011652): MORN repeat variant
SET (PF00856, IPR001214, SM00317): SET domain
194 SIN3Aoncoprotein470.292851.131Sin3_corepress (PF08295, IPR013194, SM00761): Sin3 family co-repressor
PAH (PF02671, IPR003822, SM00309): Paired amphipathic helix repeat
Sin3a_C (PF16879, IPR031693): C-terminal domain of Sin3a protein
195 SIN3Binteractor160.51749.601Sin3_corepress (PF08295, IPR013194, SM00761): Sin3 family co-repressor
PAH (PF02671, IPR003822, SM00309): Paired amphipathic helix repeat
Sin3a_C (PF16879, IPR031693): C-terminal domain of Sin3a protein
196 SIRT7interactor300.234306.674DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563)
SIR2 (PF02146, IPR003000): Sir2 family
197 SMAD2suppressor300.347196.144MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
198 SMAD3oncoprotein420.301409.616MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
199 SMARCA1interactor120.33347.510ATP-synt_E (PF05680, IPR008386): ATP synthase E chain
HAND (PF09110, IPR015194): HAND
SLIDE (PF09111, IPR015195): SLIDE
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
DBINO (PF13892, IPR020838): DNA-binding domain
200 SMARCA2suppressor620.241818.651DUF1168 (PF06658, IPR009548): Protein of unknown function (DUF1168)
DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840)
HSA (PF07529, IPR014012, SM00573): HSA
QLQ (PF08880, IPR014978, SM00951): QLQ
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
YL1 (PF05764, IPR008895): YL1 nuclear protein
BRK (PF07533, IPR006576, SM00592): BRK domain
DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052)
EPL1 (PF10513, IPR019542): Enhancer of polycomb-like
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
201 SMARCAD1interactor240.40286.974CUE (PF02845, IPR003892, SM00546): CUE domain
Pox_D5 (PF03288, IPR004968): Poxvirus D5 protein-like
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
202 SMARCB1suppressor570.276581.258SNF5 (PF04855, IPR006939): SNF5 / SMARCB1 / INI1
203 SMARCC1suppressor740.2231090.349SWIRM (PF04433, IPR007526): SWIRM domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
DUF2618 (PF10940, IPR021237): Protein of unknown function (DUF2618)
PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1
SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal
SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal
204 SMARCC2interactor620.244736.796GHMP_kinases_N (PF00288, IPR006204): GHMP kinases N terminal domain
SWIRM (PF04433, IPR007526): SWIRM domain
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1
SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal
SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal
205 SMARCD1interactor450.323376.817ATP-synt_G (PF04718, IPR006808): Mitochondrial ATP synthase g subunit
DivIC (PF04977, IPR007060): Septum formation initiator
SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain
206 SMARCD2interactor270.51975.720SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain
207 SMARCD3interactor230.51068.182SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain
208 SMARCE1interactor540.269802.747DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
GCN5L1 (PF06320, IPR009395): GCN5-like protein 1 (GCN5L1)
Ndc1_Nup (PF09531, IPR019049): Nucleoporin protein Ndc1-Nup
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
Ferlin_C (PF16165, IPR032362): Ferlin C-terminus
209 SMC3oncoprotein230.285143.050SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
210 SNW1protein found in more fusions500.1811299.050SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
SIR4_SID (PF16991, IPR031556): Sir4 SID domain
211 SP1protein found in more fusions440.330406.443zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding
Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
Miga (PF10265, IPR019392): Mitoguardin
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
212 SPATA2interactor100zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
213 SRFinteractor140.42333.121SRF-TF (PF00319, IPR002100, SM00432): SRF-type transcription factor (DNA-binding and dimerisation domain)
214 SS18oncoprotein260.60354.919SSXT (PF05030, IPR007726): SSXT protein (N-terminal region)
Rrn6 (PF10214, IPR019350): RNA polymerase I-specific transcription-initiation factor
215 SS18L1oncoprotein150.42922.611DUF1313 (PF07011, IPR009741): Protein of unknown function (DUF1313)
SSXT (PF05030, IPR007726): SSXT protein (N-terminal region)
216 STAT1suppressor210.34771.808SH2 (PF00017, IPR000980, SM00252): SH2 domain
STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain
STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain
STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
STAT1_TAZ2bind (PF12162, IPR022752): STAT1 TAZ2 binding domain
217 STAT2oncoprotein80.4644.559SH2 (PF00017, IPR000980, SM00252): SH2 domain
STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain
STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain
STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
STAT2_C (PF12188, IPR022756): Signal transducer and activator of transcription 2 C terminal
218 STAT3suppressor260.40788.360SH2 (PF00017, IPR000980, SM00252): SH2 domain
STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain
STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain
STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
219 STAT5Asuppressor110.4678.693SH2 (PF00017, IPR000980, SM00252): SH2 domain
STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain
STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain
STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
220 STK11suppressor60.40067.249Pkinase (PF00069, IPR000719): Protein kinase domain
221 STK24interactor50.33337.600DUF1241 (PF06840, IPR009652): Protein of unknown function (DUF1241)
Pkinase (PF00069, IPR000719): Protein kinase domain
222 TAF10interactor80.35710.533TFIID_30kDa (PF03540, IPR003923): Transcription initiation factor TFIID 23-30kDa subunit
223 TBX5suppressor21.0000T-box (PF00907, IPR001699, SM00425): T-box
224 TEX11interactor30.33315.714SPO22 (PF08631, IPR013940): Meiosis protein SPO22/ZIP4 like
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
DUF2547 (PF10818, IPR020508): Protein of unknown function (DUF2547)
TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat
AAA_28 (PF13521): AAA domain
TPR_19 (PF14559): Tetratricopeptide repeat
225 TOP2Boncoprotein200.40571.632CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
DASH_Spc19 (PF08287, IPR013251): Spc19
DNA_gyraseB (PF00204, IPR013506): DNA gyrase B
DTHCT (PF08070, IPR012542): DTHCT (NUC029) region
HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
Toprim (PF01751, IPR006171, SM00493): Toprim domain
Anophelin (PF10731, IPR018932): Thrombin inhibitor from mosquito
DNA_topoisoIV (PF00521, IPR002205, SM00434): DNA gyrase/topoisomerase IV, subunit A
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
TOPRIM_C (PF16898, IPR031660): C-terminal associated domain of TOPRIM
226 TOPBP1protein found in more fusions80.5244.954BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
PTCB-BRCT (PF12738, IPR001357): twin BRCT domain
RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
227 TP53suppressor790.1782413.775DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
228 TPM1protein found in more fusions110.289100.441Tropomyosin (PF00261, IPR000533): Tropomyosin
Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
229 TPM3oncoprotein150.253155.988Tropomyosin (PF00261, IPR000533): Tropomyosin
Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
230 TPRoncoprotein100.24453.486Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus
ZapB (PF06005, IPR009252): Cell division protein ZapB
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
IncA (PF04156, IPR007285): IncA protein
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
XhlA (PF10779, IPR019715): Haemolysin XhlA
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein
DUF3373 (PF11853, IPR021803): Protein of unknown function (DUF3373)
DUF4107 (PF13389, IPR025180): Protein of unknown function (DUF4107)
JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II
CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour
DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
231 TRIM28protein found in more fusions380.299211.630ASFV_J13L (PF05568, IPR008385): African swine fever virus J13L protein
K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
PHD (PF00628, IPR019787, SM00249): PHD-finger
FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2
232 TRIM29protein found in more fusions70.06770.586MIS13 (PF08202, IPR013218): Mis12-Mtw1 protein family
TP2 (PF01254, IPR000678): Nuclear transition protein 2
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
233 TRIP13interactor120.38261.578AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
234 TSC22D3protein found in more fusions80.52425.617TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
235 TSHZ3interactor100LMP (PF04778, IPR006864): LMP repeated region
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
zf-met (PF12874): Zinc-finger of C2H2 type
zf-C2HE (PF16278, IPR032566): C2HE / C2H2 / C2HC zinc-binding finger
236 TUBGCP4interactor30.6671.138Spc97_Spc98 (PF04130, IPR007259): Spc97 / Spc98 family
237 UBCprotein found in more fusions420.1621051.183ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
238 UPF1interactor120.6067.310UPF1_Zn_bind (PF09416, IPR018999): RNA helicase (UPF2 interacting domain)
AAA_11 (PF13086): AAA domain
AAA_12 (PF13087): AAA domain
239 USF1oncoprotein50.6670.554HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
240 USP15oncoprotein140.46272.066UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
DUSP (PF06337, IPR006615, SM00695): DUSP domain
Ubiquitin_3 (PF14836, IPR028135): Ubiquitin-like domain
241 VAPAinteractor60.7332.222DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
UL45 (PF05473, IPR008646): UL45 protein, carbohydrate-binding C-type lectin-like
Motile_Sperm (PF00635, IPR000535): MSP (Major sperm protein) domain
242 VPS28interactor30.33325.665VPS28 (PF03997, IPR007143): VPS28 protein
243 WDR77oncoprotein140.38537.457LT-IIB (PF06453, IPR010503): Type II heat-labile enterotoxin , B subunit (LT-IIB)
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
244 WHSC1L1suppressor110.40016.435PHD (PF00628, IPR019787, SM00249): PHD-finger
Presenilin (PF01080, IPR001108): Presenilin
PWWP (PF00855, IPR000313, SM00293): PWWP domain
SET (PF00856, IPR001214, SM00317): SET domain
zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain
zf-HC5HC2H_2 (PF13832): PHD-zinc-finger like domain
FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2
245 WWOXsuppressor170.27990.754adh_short (PF00106, IPR002198): short chain dehydrogenase
WW (PF00397, IPR001202, SM00456): WW domain
246 ZEB1interactor41.0000CDC27 (PF09507, IPR019038): DNA polymerase subunit Cdc27
zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding
GET2 (PF08690, IPR028143): GET complex subunit GET2
Pox_Ag35 (PF03286, IPR004966): Pox virus Ag35 surface protein
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
247 ZMIZ2interactor40.8330.198zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger
248 ZMYND8oncoprotein70.76212.597DUF1640 (PF07798, IPR024461): Protein of unknown function (DUF1640)
Mucin (PF01456, IPR000458): Mucin-like glycoprotein
PHD (PF00628, IPR019787, SM00249): PHD-finger
PWWP (PF00855, IPR000313, SM00293): PWWP domain
RNA_pol_Rbc25 (PF08292, IPR013238): RNA polymerase III subunit Rpc25
TCP (PF03634, IPR005333): TCP family transcription factor
zf-MYND (PF01753, IPR002893): MYND finger
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
DUF3544 (PF12064, IPR021931): Domain of unknown function (DUF3544)
CAML (PF14963, IPR016719): Calcium signal-modulating cyclophilin ligand
249 ZSCAN32interactor200KRAB (PF01352, IPR001909, SM00349): KRAB box
SCAN (PF02023, IPR003309, SM00431): SCAN domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
Mu-like_Com (PF10122, IPR019294): Mu-like prophage protein Com
DUF3613 (PF12266, IPR022053): Protein of unknown function (DUF3613)
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
Myb_DNA-bind_4 (PF13837): Myb/SANT-like DNA-binding domain
250 ZW10interactor40.6672.669Zw10 (PF06248, IPR009361): Centromere/kinetochore Zw10
DUF2203 (PF09969, IPR018699): Uncharacterized conserved protein (DUF2203)
251 ZZEF1interactor209.450ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
CUB (PF00431, IPR000859, SM00042): CUB domain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair

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