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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins SMARCA1, TSC22D1 (from a repository: Sat Aug 24 06:52:51 2019)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)122
The number (and %) of the onco-proteins25 (20.49 %)
The number (and %) of the tumor suppressors19 (15.57 %)
Total number of binary PPIs (saturation %)431 (5.84 %)
The number (and %) of affected PPIs122 (28.31 %)
The number of possible different fusions19
PPI diameter4
PPI radius2
The average degree of PPI6.443
Assortativity coefficient-0.3374
The network average Clustering coefficient0.399
The number (and %) of a zero Clustering coefficients27 (22.13 %)
The number (and %) of a zero Betweenness Centrality30 (24.59 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: TSC22D1,SMARCA1 All fusions
Proteins found in more fusions CD2AP (see 1 fusions); SNRNP200 (see 2 fusions); GRK5 (see 2 fusions); RUVBL1 (see 1 fusions); BMPR1A (see 1 fusions); NCOA5 (see 1 fusions); CHD3 (see 1 fusions); TSC22D1 (see 4 fusions); SMARCC1 (see 2 fusions); RPL5 (see 1 fusions); PARP1 (see 1 fusions); TSC22D1/MTR (see 1 fusions); CRMP1 (see 1 fusions); USF1 (see 3 fusions); FAF1 (see 3 fusions); VIM (see 1 fusions); TSC22D1/FAF1 (see 1 fusions); TP53 (see 3 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 TSC22D1parental protein870.0279291.057SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
2 SMARCA1parental protein350.1391526.197ATP-synt_E (PF05680, IPR008386): ATP synthase E chain
HAND (PF09110, IPR015194): HAND
SLIDE (PF09111, IPR015195): SLIDE
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
DBINO (PF13892, IPR020838): DNA-binding domain
3 A2Minteractor200A2M (PF00207, IPR001599): Alpha-2-macroglobulin family
A2M_comp (PF07678, IPR011626): A-macroglobulin complement component
A2M_N (PF01835, IPR002890): MG2 domain
A2M_N_2 (PF07703, IPR011625): Alpha-2-macroglobulin family N-terminal region
A2M_recep (PF07677, IPR009048): A-macroglobulin receptor
MP (PF01107, IPR028919): Viral movement protein (MP)
SVA (PF05326, IPR007990): Seminal vesicle autoantigen (SVA)
Thiol-ester_cl (PF10569, IPR019565): Alpha-macro-globulin thiol-ester bond-forming region
4 ACVR1interactor90.6076.529Activin_recp (PF01064, IPR000472): Activin types I and II receptor domain
Pkinase (PF00069, IPR000719): Protein kinase domain
TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif
5 ACVR1Boncoprotein80.53644.365Activin_recp (PF01064, IPR000472): Activin types I and II receptor domain
Pkinase (PF00069, IPR000719): Protein kinase domain
TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif
6 ACVRL1interactor30.6670.333Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif
7 ALBinteractor21.0000Serum_albumin (PF00273, IPR014760, SM00103): Serum albumin family
8 APLP1interactor41.0000APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
Ints3 (PF10189, IPR019333): Integrator complex subunit 3
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
9 ARID1Boncoprotein50.7005.330ARID (PF01388, IPR001606, SM00501): ARID/BRIGHT DNA binding domain
DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908)
Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
Presenilin (PF01080, IPR001108): Presenilin
DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052)
DUF2235 (PF09994, IPR018712): Uncharacterized alpha/beta hydrolase domain (DUF2235)
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
BAF250_C (PF12031, IPR021906): SWI/SNF-like complex subunit BAF250/Osa
Spt20 (PF12090, IPR021950): Spt20 family
10 ASAH1interactor21.0000CBAH (PF02275, IPR003199): Linear amide C-N hydrolases, choloylglycine hydrolase family
NAAA-beta (PF15508, IPR029130): beta subunit of N-acylethanolamine-hydrolyzing acid amidase
11 BAG6interactor90.42922.371DUF1179 (PF06678, IPR009564): Protein of unknown function (DUF1179)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
DUF2939 (PF11159, IPR021330): Protein of unknown function (DUF2939)
DUF3538 (PF12057, IPR021925): Domain of unknown function (DUF3538)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
12 BMPR1Asuppressor80.6673.567Activin_recp (PF01064, IPR000472): Activin types I and II receptor domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif
13 BMPR1Binteractor50.8330.333Activin_recp (PF01064, IPR000472): Activin types I and II receptor domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif
14 BPTFinteractor110.45547.749Arc_PepC_II (PF06847, IPR009655): Archaeal Peptidase A24 C-terminus Type II
CobT (PF06213, IPR006538): Cobalamin biosynthesis protein CobT
DDT (PF02791, IPR004022, SM00571): DDT domain
DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
GRP (PF07172, IPR010800): Glycine rich protein family
OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain
PHD (PF00628, IPR019787, SM00249): PHD-finger
SDA1 (PF05285, IPR007949): SDA1
Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
WHIM1 (PF15612, IPR028942): WSTF, HB1, Itc1p, MBD9 motif 1
WSD (PF15613, IPR028941): Williams-Beuren syndrome DDT (WSD), D-TOX E motif
CCSAP (PF15748, IPR029774): Centriole, cilia and spindle-associated
PNISR (PF15996, IPR031937): Arginine/serine-rich protein PNISR
15 C14orf1interactor100Erg28 (PF03694, IPR005352): Erg28 like protein
16 C17orf49interactor80.57120.455Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
17 CA10interactor21.0000Carb_anhydrase (PF00194, IPR001148, SM01057): Eukaryotic-type carbonic anhydrase
18 CACNA1Ainteractor30.6671.000Ca_chan_IQ (PF08763, IPR014873, SM01062): Voltage gated calcium channel IQ domain
GRP (PF07172, IPR010800): Glycine rich protein family
Ion_trans (PF00520, IPR005821): Ion transport protein
Roughex (PF06020, IPR009259): Drosophila roughex protein
SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region
GPHH (PF16905, IPR031649): Voltage-dependent L-type calcium channel, IQ-associated
19 CARHSP1interactor100DUF4339 (PF14237, IPR025640): Domain of unknown function (DUF4339)
20 CCDC90Binteractor100DUF1640 (PF07798, IPR024461): Protein of unknown function (DUF1640)
21 CD2APprotein found in more fusions50.5003.462SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
betaPIX_CC (PF16523, IPR032409): betaPIX coiled coil
22 CDK2suppressor160.276362.856Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
23 CHD3oncoprotein110.378208.786CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain
CHDNT (PF08073, IPR012958): CHDNT (NUC034) domain
Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
DUF1086 (PF06461, IPR009462, SM01146): Domain of Unknown Function (DUF1086)
DUF1087 (PF06465, IPR009463, SM01147): Domain of Unknown Function (DUF1087)
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
PHD (PF00628, IPR019787, SM00249): PHD-finger
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SMN (PF06003, IPR010304): Survival motor neuron protein (SMN)
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
DUF2956 (PF11169, IPR021339): Protein of unknown function (DUF2956)
FAM176 (PF14851): FAM176 family
24 COPB2interactor50.5007.773Coatomer_WDAD (PF04053, IPR006692): Coatomer WD associated region
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
25 CORO2Boncoprotein100DivIC (PF04977, IPR007060): Septum formation initiator
DUF1899 (PF08953, IPR015048, SM01166): Domain of unknown function (DUF1899)
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
WD40_4 (PF16300): Type of WD40 repeat
26 CRMP1protein found in more fusions50.50015.198Amidohydro_1 (PF01979, IPR006680): Amidohydrolase family
Amidohydro_3 (PF07969, IPR013108): Amidohydrolase family
27 DDAH2interactor100Amidinotransf (PF02274, IPR003198): Amidinotransferase
28 DDX21interactor70.38178.482CRT10 (PF08728, IPR014839): CRT10
DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
GUCT (PF08152, IPR012562): GUCT (NUC152) domain
Sulfatase (PF00884, IPR000917): Sulfatase
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal
29 DEF6interactor100ArgK (PF03308, IPR005129): ArgK protein
HSP70 (PF00012, IPR013126): Hsp70 protein
PH (PF00169, IPR001849, SM00233): PH domain
zf-C4H2 (PF10146, IPR018482): Zinc finger-containing protein
EF-hand_6 (PF13405, IPR002048): EF-hand domain
30 DHDHinteractor100GFO_IDH_MocA (PF01408, IPR000683): Oxidoreductase family, NAD-binding Rossmann fold
31 DNAAF5interactor30.3335.877HEAT (PF02985, IPR000357): HEAT repeat
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
RasGEF_N_2 (PF14663, IPR029453): Rapamycin-insensitive companion of mTOR RasGEF_N domain
32 DNMT3Bsuppressor60.533100.383DNA_methylase (PF00145, IPR001525): C-5 cytosine-specific DNA methylase
PWWP (PF00855, IPR000313, SM00293): PWWP domain
33 DYNC1H1interactor90.194207.297AAA_5 (PF07728, IPR011704): AAA domain (dynein-related subfamily)
DHC_N1 (PF08385, IPR013594): Dynein heavy chain, N-terminal region 1
DHC_N2 (PF08393, IPR013602): Dynein heavy chain, N-terminal region 2
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948)
Dynein_heavy (PF03028, IPR004273): Dynein heavy chain and region D6 of dynein motor
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
AAA_6 (PF12774): Hydrolytic ATP binding site of dynein motor region D1
AAA_7 (PF12775): P-loop containing dynein motor region D3
MT (PF12777, IPR024743): Microtubule-binding stalk of dynein motor
AAA_8 (PF12780, IPR024317): P-loop containing dynein motor region D4
AAA_9 (PF12781): ATP-binding dynein motor region D5
34 EEDsuppressor180.279764.708WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
35 EMC1interactor202.246DUF1620 (PF07774, IPR011678): Protein of unknown function (DUF1620)
PQQ (PF01011, IPR002372, SM00564): PQQ enzyme repeat
PQQ_2 (PF13360, IPR002372): PQQ-like domain
36 EPPK1interactor30.6671.500DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840)
HupF_HypC (PF01455, IPR001109): HupF/HypC family
Plectin (PF00681, IPR001101, SM00250): Plectin repeat
RPA_interact_N (PF14766, IPR028158): Replication protein A interacting N-terminal
37 FAF1protein found in more fusions40.6672.246UBX (PF00789, IPR001012, SM00166): UBX domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
AAA_11 (PF13086): AAA domain
UBA_4 (PF14555): UBA-like domain
38 FAM20Cinteractor100Fam20C (PF06702, IPR009581): Golgi casein kinase, C-terminal, Fam20
FAM198 (PF15051, IPR029207): FAM198 protein
39 FBN3interactor100EGF (PF00008, IPR000742, SM00181): EGF-like domain
EGF_2 (PF07974, IPR013111): EGF-like domain
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
TB (PF00683, IPR017878): TB domain
hEGF (PF12661, IPR013032): Human growth factor-like EGF
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site
40 FOXC1suppressor40.66716.230TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence
Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
PAF (PF15715, IPR031444): PCNA-associated factor
PRIMA1 (PF16101): Proline-rich membrane anchor 1
41 FOXE1oncoprotein50.4008.970Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
42 FOXG1oncoprotein60.13362.553SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region
SPX (PF03105, IPR004331): SPX domain
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
43 FOXJ2interactor31.0000SARAF (PF06682, IPR009567): SOCE-associated regulatory factor of calcium homoeostasis
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
Spt20 (PF12090, IPR021950): Spt20 family
Pro-rich (PF15240, IPR026086): Proline-rich
44 FOXK2interactor110.36478.030FHA (PF00498, IPR000253, SM00240): FHA domain
Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
45 FOXL1oncoprotein40.16727.257Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
46 FOXQ1interactor50.20020.036Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
47 GCN1interactor40.50019.245Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
HEAT (PF02985, IPR000357): HEAT repeat
CLASP_N (PF12348, IPR024395): CLASP N terminal
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
TFCD_C (PF12612, IPR022577): Tubulin folding cofactor D C terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
48 GNB2interactor50.50017.581WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
CALM_bind (PF16025): Calcium-dependent calmodulin binding
WD40_like (PF17005, IPR031544): WD40-like domain
49 GNB5interactor100WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
WD40_like (PF17005, IPR031544): WD40-like domain
50 GRK5protein found in more fusions40.6670.500Pkinase (PF00069, IPR000719): Protein kinase domain
RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
51 GSTK1interactor60.4006.734DSBA (PF01323, IPR001853): DSBA-like thioredoxin domain
52 HIST1H3Ainteractor140.295229.419Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
53 HMGXB4oncoprotein50.500147.858DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
RNA_polI_A34 (PF08208, IPR013240): DNA-directed RNA polymerase I subunit RPA34.5
Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
DUF4171 (PF13775, IPR025228): Domain of unknown function (DUF4171)
RMP (PF14996, IPR029239): Retinal Maintenance
54 HNRNPMinteractor100.422113.287RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNP_M (PF11532, IPR024666): Heterogeneous nuclear ribonucleoprotein M
Collagen_mid (PF15984, IPR031929): Bacterial collagen, middle region
55 IARSinteractor70.286115.549Anticodon_1 (PF08264, IPR013155): Anticodon-binding domain of tRNA
tRNA-synt_1 (PF00133, IPR002300): tRNA synthetases class I (I, L, M and V)
56 IFI16suppressor80.17995.859HIN (PF02760, IPR004021): HIN-200/IF120x domain
PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain
Mitofilin (PF09731, IPR019133): Mitochondrial inner membrane protein
57 IKBKAPinteractor80.47622.066IKI3 (PF04762, IPR006849): IKI3 family
Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS
MMU163 (PF17119, IPR031342): Mitochondrial protein up-regulated during meiosis
58 KMT2Boncoprotein2017.331FLO_LFY (PF01698, IPR002910): Floricaula / Leafy protein
FYRC (PF05965, IPR003889, SM00542): F/Y rich C-terminus
FYRN (PF05964, IPR003888, SM00541): F/Y-rich N-terminus
GRP (PF07172, IPR010800): Glycine rich protein family
PHD (PF00628, IPR019787, SM00249): PHD-finger
SET (PF00856, IPR001214, SM00317): SET domain
zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
Fer4_2 (PF12797, IPR001450): 4Fe-4S binding domain
zf-HC5HC2H (PF13771): PHD-like zinc-binding domain
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3
59 KMT2Csuppressor2017.331AT_hook (PF02178, IPR017956, SM00384): AT hook motif
FYRC (PF05965, IPR003889, SM00542): F/Y rich C-terminus
FYRN (PF05964, IPR003888, SM00541): F/Y-rich N-terminus
SLC12 (PF03522, IPR018491): Solute carrier family 12
MAP7 (PF05672, IPR008604): MAP7 (E-MAP-115) family
PHD (PF00628, IPR019787, SM00249): PHD-finger
SET (PF00856, IPR001214, SM00317): SET domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
zf-HC5HC2H (PF13771): PHD-like zinc-binding domain
zf-HC5HC2H_2 (PF13832): PHD-zinc-finger like domain
60 LARP7interactor50.20060.487Agouti (PF05039, IPR007733, SM00792): Agouti protein
DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
La (PF05383, IPR006630, SM00715): La domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RRM_3 (PF08777, IPR014886): RNA binding motif
61 LRIF1interactor80.52444.413LRIF1 (PF15741, IPR026191): Ligand-dependent nuclear receptor-interacting factor 1
62 MAP3K12interactor21.0000APH (PF01636, IPR002575): Phosphotransferase enzyme family
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
63 MAXsuppressor70.33344.115ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
SlyX (PF04102, IPR007236): SlyX
64 MCM3APinteractor2019.705RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SAC3_GANP (PF03399, IPR005062): SAC3/GANP family
G_path_suppress (PF15991, IPR026094): G-protein pathway suppressor
CID_GANP (PF16766, IPR031910): Binding region of GANP to ENY2
NupH_GANP (PF16768, IPR031908): Nucleoporin homology of Germinal-centre associated nuclear protein
MCM3AP_GANP (PF16769, IPR031907): MCM3AP domain of GANP
65 MTRprotein found in more fusions202.246B12-binding (PF02310, IPR006158): B12 binding domain
B12-binding_2 (PF02607, IPR003759, SM01018): B12 binding domain
IPT (PF01745, IPR002648, SM00429): Isopentenyl transferase
Met_synt_B12 (PF02965, IPR004223): Vitamin B12 dependent methionine synthase, activation domain
Pterin_bind (PF00809, IPR000489): Pterin binding enzyme
S-methyl_trans (PF02574, IPR003726): Homocysteine S-methyltransferase
DUF2760 (PF10816, IPR021212): Domain of unknown function (DUF2760)
66 NANOGinteractor40.6671.000Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
67 NCOA5suppressor40.6672.469Macoilin (PF09726, IPR019130): Transmembrane protein
68 NDUFA9interactor202.246Epimerase (PF01370, IPR001509): NAD dependent epimerase/dehydratase family
69 NRBP1suppressor50.4006.857Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
70 NTRK1oncoprotein390.0731631.065I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
71 NUP50interactor70.286127.027NUP50 (PF08911, IPR015007): NUP50 (Nucleoporin 50 kDa)
Ran_BP1 (PF00638, IPR000156, SM00160): RanBP1 domain
72 NUP93oncoprotein50.30030.138Nic96 (PF04097, IPR007231): Nup93/Nic96
73 OTUB1interactor130.269143.105Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain
74 PARP1suppressor90.32152.676BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
PADR1 (PF08063, IPR012982): PADR1 (NUC008) domain
PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain
PARP_reg (PF02877, IPR004102): Poly(ADP-ribose) polymerase, regulatory domain
WGR (PF05406, IPR008893, SM00773): WGR domain
zf-PARP (PF00645, IPR001510): Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
75 PDHBinteractor30.3334.162Transket_pyr (PF02779, IPR005475, SM00861): Transketolase, pyrimidine binding domain
Transketolase_C (PF02780, IPR005476): Transketolase, C-terminal domain
76 PGRsuppressor50.5005.891Prog_receptor (PF02161, IPR000128): Progesterone receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
77 POLE3interactor21.0000BUD22 (PF09073, IPR015158): BUD22
CBFD_NFYB_HMF (PF00808, IPR003958): Histone-like transcription factor (CBF/NF-Y) and archaeal histone
78 PRKCIinteractor100PB1 (PF00564, IPR000270, SM00666): PB1 domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
79 PTNoncoprotein40.6671.182PTN_MK_C (PF01091, IPR020090): PTN/MK heparin-binding protein family, C-terminal domain
PTN_MK_N (PF05196, IPR020089): PTN/MK heparin-binding protein family, N-terminal domain
80 QARSinteractor40.8332.246tRNA-synt_1c (PF00749, IPR020058): tRNA synthetases class I (E and Q), catalytic domain
tRNA-synt_1c_C (PF03950, IPR020059): tRNA synthetases class I (E and Q), anti-codon binding domain
tRNA_synt_1c_R1 (PF04558, IPR007639): Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1
tRNA_synt_1c_R2 (PF04557, IPR007638): Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2
81 RBBP4oncoprotein140.451104.235eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein
CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
82 RBBP7suppressor120.54544.066WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein
CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
83 RBPJinteractor30.6670.182BTD (PF09270, IPR015350): Beta-trefoil DNA-binding domain
LAG1-DNAbind (PF09271, IPR015351): LAG1, DNA binding
TIG (PF01833, IPR002909): IPT/TIG domain
84 RGS1oncoprotein21.0000RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
85 RPA3interactor80.238138.496Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3
86 RPL5suppressor70.53361.985Ribosomal_L18_c (PF14204, IPR025607): Ribosomal L18 C-terminal region
Ribosomal_L5e (PF17144): Ribosomal large subunit proteins 60S L5, and 50S L18
87 RPS2interactor70.47626.848Ribosomal_S5 (PF00333, IPR013810): Ribosomal protein S5, N-terminal domain
Ribosomal_S5_C (PF03719, IPR005324): Ribosomal protein S5, C-terminal domain
88 RUVBL1oncoprotein90.429154.774TIP49 (PF06068, IPR010339): TIP49 C-terminus
89 SETD1Ainteractor50.20023.483E7 (PF00527, IPR000148): E7 protein, Early protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SET (PF00856, IPR001214, SM00317): SET domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
N-SET (PF11764, IPR024657): COMPASS (Complex proteins associated with Set1p) component N
DUF4632 (PF15451, IPR027952): Domain of unknown function (DUF4632)
DUF4667 (PF15700, IPR031426): Domain of unknown function (DUF4667)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
90 SETDB1interactor80.35753.169MBD (PF01429, IPR001739, SM00391): Methyl-CpG binding domain
Pre-SET (PF05033, IPR007728): Pre-SET motif
SET (PF00856, IPR001214, SM00317): SET domain
DUF4537 (PF15057, IPR032770): Domain of unknown function (DUF4537)
PNRC (PF15365, IPR028322): Proline-rich nuclear receptor coactivator
91 SFXN1interactor202.246Mtc (PF03820, IPR004686): Tricarboxylate carrier
92 SLC25A22interactor202.246Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
DUF4257 (PF14074, IPR025353): Protein of unknown function (DUF4257)
93 SMAD6interactor70.6193.967MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
94 SMAD7interactor80.60741.336MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
95 SMARCA4suppressor120.364141.065DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840)
HSA (PF07529, IPR014012, SM00573): HSA
QLQ (PF08880, IPR014978, SM00951): QLQ
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
BRK (PF07533, IPR006576, SM00592): BRK domain
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
DUF4065 (PF13274, IPR025272): Protein of unknown function (DUF4065)
SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
96 SMARCA5interactor300.180950.489HAND (PF09110, IPR015194): HAND
SLIDE (PF09111, IPR015195): SLIDE
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
DBINO (PF13892, IPR020838): DNA-binding domain
RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein
97 SMARCC1suppressor90.64342.055SWIRM (PF04433, IPR007526): SWIRM domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
DUF2618 (PF10940, IPR021237): Protein of unknown function (DUF2618)
PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1
SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal
SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal
98 SMARCC2interactor120.394109.450GHMP_kinases_N (PF00288, IPR006204): GHMP kinases N terminal domain
SWIRM (PF04433, IPR007526): SWIRM domain
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1
SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal
SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal
99 SNRNP200protein found in more fusions90.143178.981DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
DUF603 (PF04645, IPR006739): Protein of unknown function, DUF603
Sec63 (PF02889, IPR004179, SM00973): Sec63 Brl domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
100 SP110oncoprotein100Asp-B-Hydro_N (PF05279, IPR007943): Aspartyl beta-hydroxylase N-terminal region
PHD (PF00628, IPR019787, SM00249): PHD-finger
SAND (PF01342, IPR000770, SM00258): SAND domain
HSR (PF03172, IPR004865): HSR domain
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
101 SPACA9interactor100DUF4561 (PF15120, IPR027818): Domain of unknown function (DUF4561)
102 SPRED1interactor100SMC_ScpA (PF02616, IPR003768): Segregation and condensation protein ScpA
Sprouty (PF05210, IPR007875): Sprouty protein (Spry)
WH1 (PF00568, IPR000697, SM00461): WH1 domain
103 SRPRBinteractor30.6672.246MHYT (PF03707, IPR005330): Bacterial signalling protein N terminal repeat
SRPRB (PF09439, IPR019009): Signal recognition particle receptor beta subunit
104 TAF5Linteractor21.0000TFIID_NTD2 (PF04494, IPR007582): WD40 associated region in TFIID subunit, NTD2 domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
105 TEAD2interactor40.6675.978TEA (PF01285, IPR000818, SM00426): TEA/ATTS domain family
106 TFPToncoprotein31.0000GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor
107 TGFBR1oncoprotein60.4674.131Activin_recp (PF01064, IPR000472): Activin types I and II receptor domain
Pkinase (PF00069, IPR000719): Protein kinase domain
TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif
108 TGFBR2suppressor60.7331.467ecTbetaR2 (PF08917, IPR015013): Transforming growth factor beta receptor 2 ectodomain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
109 TLE1interactor3026.593TLE_N (PF03920, IPR005617): Groucho/TLE N-terminal Q-rich domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
110 TP53suppressor240.138955.807DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
111 TSC22D4interactor30.6671.000AflR (PF08493, IPR013700): Aflatoxin regulatory protein
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
112 TTI1interactor50.50082.360Dopey_N (PF04118, IPR007249): Dopey, N-terminal
HEAT (PF02985, IPR000357): HEAT repeat
VHS (PF00790, IPR002014, SM00288): VHS domain
CLASP_N (PF12348, IPR024395): CLASP N terminal
113 UBE2D1interactor40.6671.000UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
114 UNC119interactor100GMP_PDE_delta (PF05351, IPR008015): GMP-PDE, delta subunit
115 UNKinteractor50.4009.310MbeD_MobD (PF04899, IPR006983): MbeD/MobD like
NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
zf-CCCH_2 (PF14608): RNA-binding, Nab2-type zinc finger
Torus (PF16131, IPR032297): Torus domain
116 USF1oncoprotein100.41715.156HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
117 VIMsuppressor100.41750.412Filament (PF00038, IPR001664): Intermediate filament protein
Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region
118 WDR73interactor100WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
119 WDYHV1interactor21.0000Nt_Gln_amidase (PF09764, IPR023128): N-terminal glutamine amidase
120 WIZinteractor60.067236.501AnfO_nitrog (PF09582, IPR014287): Iron only nitrogenase protein AnfO (AnfO_nitrog)
C1_2 (PF03107, IPR004146): C1 domain
Zn-ribbon_8 (PF09723, IPR013429, SM00834): Zinc ribbon domain
Enterotoxin_ST (PF02048, IPR001489): Heat-stable enterotoxin ST
zf-C2H2_4 (PF13894): C2H2-type zinc finger
121 WNK1interactor31.0000SynMuv_product (PF06047, IPR009269): Ras-induced vulval development antagonist
Pkinase (PF00069, IPR000719): Protein kinase domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
OSR1_C (PF12202, IPR024678): Oxidative-stress-responsive kinase 1 C terminal
122 ZC3HC1interactor100Rsm1 (PF08600, IPR013909): Rsm1-like
zf-C3HC (PF07967, IPR012935): C3HC zinc finger-like

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