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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins C5orf42, RPS4XP7 (from a repository: Tue Apr 14 19:06:52 2020)

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)6
The number (and %) of the onco-proteins2 (33.33 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)8 (53.33 %)
The number (and %) of affected PPIs4 (50.00 %)
The number of possible different fusions3
PPI diameter2
PPI radiusinf
The average degree of PPI1.667
Assortativity coefficient-0.4082
The network average Clustering coefficient0.361
The number (and %) of a zero Clustering coefficients3 (50.00 %)
The number (and %) of a zero Betweenness Centrality5 (83.33 %)


List of the fusions

PPI for parental proteins: C5orf42,RPS4XP7 All fusions
Proteins found in more fusions SRPK2 (see 1 fusions); PAK1 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Domains (Pfam, InterPro, SMART): description
1 C5orf42parental protein40.16710.000Joubert (PF15392, IPR028236): Joubert syndrome-associated
2 RPS4XP7interactor000NA
3 CAND1interactor31.0000Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981)
HEAT (PF02985, IPR000357): HEAT repeat
TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20)
RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
4 PAK1oncoprotein200PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain
Pkinase (PF00069, IPR000719): Protein kinase domain
5 SRPK2oncoprotein31.0000DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
Pkinase (PF00069, IPR000719): Protein kinase domain
S-antigen (PF05756, IPR008825): S-antigen protein
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
6 TUBGCP4interactor100Spc97_Spc98 (PF04130, IPR007259): Spc97 / Spc98 family

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