Find Fusion Network

Fusion ID:
Protein names:

Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins CAMLG, CDCP1 (from a repository: Tue Mar 7 15:45:55 2017)

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Force Directed
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)18
The number (and %) of the onco-proteins2 (11.11 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)21 (13.73 %)
The number (and %) of affected PPIs16 (76.19 %)
The number of possible different fusions2
PPI diameter2
PPI radiusinf
The average degree of PPI1.889
Assortativity coefficient-0.1335
The network average Clustering coefficient0.112
The number (and %) of a zero Clustering coefficients15 (83.33 %)
The number (and %) of a zero Betweenness Centrality16 (88.89 %)


List of the fusions

PPI for parental proteins: CAMLG,CDCP1 All fusions
Proteins found in more fusions EGFR (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Domains (Pfam, InterPro, SMART): description
1 CAMLGparental protein130.013154.000CAML (PF14963, IPR016719): Calcium signal-modulating cyclophilin ligand
2 CDCP1parental protein306.000CUB (PF00431, IPR000859, SM00042): CUB domain
3 ALBinteractor100Serum_albumin (PF00273, IPR014760, SM00103): Serum albumin family
4 CLK1interactor200PDGF_N (PF04692, IPR006782): Platelet-derived growth factor, N terminal region
Pkinase (PF00069, IPR000719): Protein kinase domain
5 EGFRoncoprotein200Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
6 EVC2interactor100HBS1_N (PF08938, IPR015033): HBS1 N-terminus
DUF342 (PF03961, IPR005646): Protein of unknown function (DUF342)
Histone_HNS (PF00816, IPR001801): H-NS histone family
EVC2_like (PF12297, IPR022076): Ellis van Creveld protein 2 like protein
7 KCNA2interactor200Ion_trans (PF00520, IPR005821): Ion transport protein
BTB_2 (PF02214, IPR003131): BTB/POZ domain
Sigma_reg_N (PF13800, IPR029101): Sigma factor regulator N-terminal
8 PPIBinteractor21.0000Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
9 RNF122interactor200zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
Prok-RING_1 (PF14446): Prokaryotic RING finger family 1
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
10 SDCBPinteractor100PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
11 TCTN2interactor100DUF1619 (PF07773, IPR011677): Protein of unknown function (DUF1619)
12 TCTN3interactor21.0000DUF1619 (PF07773, IPR011677): Protein of unknown function (DUF1619)
13 TMEM17interactor100Transmemb_17 (PF09799, IPR019184): Predicted membrane protein
DUF3043 (PF11241, IPR021403): Protein of unknown function (DUF3043)
14 TMEM216interactor100Transmemb_17 (PF09799, IPR019184): Predicted membrane protein
15 TMEM67interactor100Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like
NCD3G (PF07562, IPR011500): Nine Cysteines Domain of family 3 GPCR
Tme5_EGF_like (PF09064, IPR015149): Thrombomodulin like fifth domain, EGF-like
Meckelin (PF09773, IPR019170): Meckelin (Transmembrane protein 67)
hEGF (PF12661, IPR013032): Human growth factor-like EGF
16 TMUB1interactor100DUF347 (PF03988, IPR007136): Repeat of Unknown Function (DUF347)
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
DUF4227 (PF14004, IPR025321): Protein of unknown function (DUF4227)
17 TNFRSF13Boncoprotein100TACI-CRD2 (PF09305, IPR015384): TACI, cysteine-rich domain
18 WRBinteractor100CHD5 (PF04420, IPR028945): CHD5-like protein
DUF2868 (PF11067, IPR021296): Protein of unknown function (DUF2868)

B a c k    t o    T o p ⇑