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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins CHRM3, NORAD (from a repository: Thu Aug 8 16:05:15 2019)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)8
The number (and %) of the onco-proteins2 (25.00 %)
The number (and %) of the tumor suppressors2 (25.00 %)
Total number of binary PPIs (saturation %)9 (32.14 %)
The number (and %) of affected PPIs6 (66.67 %)
The number of possible different fusions3
PPI diameter2
PPI radiusinf
The average degree of PPI1.500
Assortativity coefficient0
The network average Clustering coefficient0.000
The number (and %) of a zero Clustering coefficients8 (100.00 %)
The number (and %) of a zero Betweenness Centrality6 (75.00 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: CHRM3,NORAD All fusions
Proteins found in more fusions ARF1 (see 2 fusions); SET (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 CHRM3parental protein4012.0007tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
GWT1 (PF06423, IPR009447): GWT1
2 NORADparental protein202.000NA
3 ARF1suppressor200Arf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family
4 ARF6oncoprotein100Arf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family
5 CSNK1A1suppressor100Pkinase (PF00069, IPR000719): Protein kinase domain
6 MOV10interactor100AAA_12 (PF13087): AAA domain
AAA_30 (PF13604): AAA domain
7 NXF1interactor200NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding
TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
8 SEToncoprotein200NAP (PF00956, IPR002164): Nucleosome assembly protein (NAP)
Nop14 (PF04147, IPR007276): Nop14-like family
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)

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