1 |
HNRNPA3 | parental protein | 113 | 0.243 | 3968.755 | IATP (PF04568, IPR007648): Mitochondrial ATPase inhibitor, IATP RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
2 |
ITSN1 | parental protein | 104 | 0.034 | 13150.037 | C2 (PF00168, IPR000008, SM00239): C2 domain VIT1 (PF01988, IPR008217): VIT family DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) FmdE (PF02663, IPR003814): FmdE, Molybdenum formylmethanofuran dehydrogenase operon GSH_synthase (PF03199, IPR004887): Eukaryotic glutathione synthase RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) SH3_9 (PF14604, IPR001452): Variant SH3 domain DUF4748 (PF15932, IPR031833): Domain of unknown function (DUF4748) INTAP (PF16617): Intersectin and clathrin adaptor AP2 binding region PH_13 (PF16652, IPR001849): Pleckstrin homology domain |
3 |
AGFG1 | interactor | 6 | 0.333 | 25.766 | ArfGap (PF01412, IPR001164, SM00105): Putative GTPase activating protein for Arf |
4 |
AGFG2 | interactor | 3 | 0.667 | 0.286 | ArfGap (PF01412, IPR001164, SM00105): Putative GTPase activating protein for Arf |
5 |
AMPH | oncoprotein | 13 | 0.282 | 101.723 | BAR (PF03114, IPR004148, SM00721): BAR domain SH3_9 (PF14604, IPR001452): Variant SH3 domain PBP_N (PF17093, IPR031375): Penicillin-binding protein N-terminus |
6 |
AP2B1 | interactor | 18 | 0.412 | 113.565 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region Alpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain B2-adapt-app_C (PF09066, IPR015151, SM01020): Beta2-adaptin appendage, C-terminal sub-domain |
7 |
AP2M1 | protein found in more fusions | 28 | 0.319 | 367.041 | Adap_comp_sub (PF00928, IPR008968): Adaptor complexes medium subunit family Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain |
8 |
ARF6 | oncoprotein | 6 | 0.200 | 52.922 | Arf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family |
9 |
ARFIP2 | interactor | 5 | 0.333 | 14.735 | Arfaptin (PF06456, IPR010504, SM01015): Arfaptin-like domain |
10 |
ARHGAP31 | interactor | 1 | 0 | 0 | RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain |
11 |
ARHGDIA | interactor | 13 | 0.500 | 32.065 | Rho_GDI (PF02115, IPR000406): RHO protein GDP dissociation inhibitor |
12 |
ARRB1 | interactor | 21 | 0.314 | 405.278 | Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain |
13 |
ASAP2 | interactor | 3 | 0.333 | 5.038 | ArfGap (PF01412, IPR001164, SM00105): Putative GTPase activating protein for Arf PH (PF00169, IPR001849, SM00233): PH domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404) SH3_9 (PF14604, IPR001452): Variant SH3 domain BAR_3 (PF16746): BAR domain of APPL family |
14 |
ATP1B1 | interactor | 5 | 0.700 | 3.171 | Na_K-ATPase (PF00287, IPR000402): Sodium / potassium ATPase beta chain |
15 |
ATP5B | interactor | 25 | 0.447 | 75.754 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain NACHT (PF05729): NACHT domain |
16 |
BTRC | oncoprotein | 20 | 0.386 | 121.645 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like |
17 |
CAND1 | interactor | 60 | 0.454 | 281.008 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981) HEAT (PF02985, IPR000357): HEAT repeat TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20) RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II |
18 |
CBL | suppressor | 22 | 0.252 | 460.677 | Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1 Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain Prok-RING_4 (PF14447): Prokaryotic RING finger family 4 zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain |
19 |
CBLB | oncoprotein | 10 | 0.500 | 65.659 | Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1 Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain Prok-RING_4 (PF14447): Prokaryotic RING finger family 4 PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
20 |
CCNO | interactor | 1 | 0 | 0 | Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain |
21 |
CD81 | interactor | 24 | 0.451 | 55.299 | Tetraspannin (PF00335, IPR018499): Tetraspanin family |
22 |
CDC42 | oncoprotein | 17 | 0.167 | 481.038 | Ras (PF00071, IPR001806, SM00173): Ras family |
23 |
CEP85L | interactor | 1 | 0 | 0 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) DUF16 (PF01519, IPR002862): Protein of unknown function DUF16 Phage_GP20 (PF06810, IPR009636): Phage minor structural protein GP20 Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein SlyX (PF04102, IPR007236): SlyX Spc42p (PF11544, IPR021611): Spindle pole body component Spc42p |
24 |
CHMP2A | interactor | 5 | 0.333 | 2.176 | Snf7 (PF03357, IPR005024): Snf7 |
25 |
CLIP2 | interactor | 1 | 0 | 0 | APG6 (PF04111, IPR007243): Autophagy protein Apg6 CAP_GLY (PF01302, IPR000938, SM01052): CAP-Gly domain CorA (PF01544, IPR002523): CorA-like Mg2+ transporter protein DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641) ZapB (PF06005, IPR009252): Cell division protein ZapB DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) Fez1 (PF06818): Fez1 Sas10 (PF09368, IPR018972): Sas10 C-terminal domain Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal BLOC1_2 (PF10046, IPR019269): Biogenesis of lysosome-related organelles complex-1 subunit 2 Caskin1-CID (PF16600): Caskin1 CASK-interaction domain BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2 |
26 |
CLK1 | interactor | 7 | 0.867 | 0.548 | PDGF_N (PF04692, IPR006782): Platelet-derived growth factor, N terminal region Pkinase (PF00069, IPR000719): Protein kinase domain |
27 |
CLTC | oncoprotein | 45 | 0.203 | 1240.194 | Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker Clathrin_propel (PF01394, IPR022365): Clathrin propeller repeat Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS Clathrin_H_link (PF13838): Clathrin-H-link |
28 |
CNBP | oncoprotein | 8 | 0.607 | 1.910 | zf-CCHC (PF00098, IPR001878): Zinc knuckle zf-ribbon_3 (PF13248): zinc-ribbon domain |
29 |
COPS5 | protein found in more fusions | 53 | 0.498 | 160.767 | JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease |
30 |
CRIP1 | interactor | 5 | 0.500 | 13.801 | LIM (PF00412, IPR001781, SM00132): LIM domain |
31 |
CRY1 | interactor | 22 | 0.386 | 42.232 | DNA_photolyase (PF00875, IPR006050): DNA photolyase FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase |
32 |
CSNK2B | interactor | 18 | 0.228 | 213.758 | CK_II_beta (PF01214, IPR000704, SM01085): Casein kinase II regulatory subunit |
33 |
CUL1 | suppressor | 59 | 0.448 | 357.253 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
34 |
CUL2 | suppressor | 41 | 0.541 | 146.680 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
35 |
CUL3 | protein found in more fusions | 72 | 0.353 | 804.377 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal |
36 |
CUL4B | oncoprotein | 32 | 0.679 | 28.609 | Cullin (PF00888, IPR001373, SM00182): Cullin family EBP50_C (PF09007, IPR015098): EBP50, C-terminal Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain PG_binding_4 (PF12229, IPR022029): Putative peptidoglycan binding domain MDFI (PF15316, IPR026134): MyoD family inhibitor |
37 |
CUL5 | suppressor | 41 | 0.578 | 83.581 | Cullin (PF00888, IPR001373, SM00182): Cullin family GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
38 |
CUL7 | protein found in more fusions | 55 | 0.356 | 269.906 | ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7 |
39 |
CYB5B | interactor | 3 | 1.000 | 0 | Cyt-b5 (PF00173, IPR001199, SM01117): Cytochrome b5-like Heme/Steroid binding domain MIP (PF00230, IPR000425): Major intrinsic protein |
40 |
CYTH1 | interactor | 3 | 0.667 | 7.434 | DUF342 (PF03961, IPR005646): Protein of unknown function (DUF342) PH (PF00169, IPR001849, SM00233): PH domain Sec7 (PF01369, IPR000904, SM00222): Sec7 domain |
41 |
DAB2 | suppressor | 8 | 0.607 | 25.851 | PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) zf-C2H2_assoc3 (PF16637): Putative zinc-finger between two C2H2 zinc-fingers on Patz |
42 |
DCUN1D1 | interactor | 32 | 0.694 | 27.832 | Cullin_binding (PF03556, IPR005176): Cullin binding UBA_4 (PF14555): UBA-like domain |
43 |
DDX17 | protein found in more fusions | 56 | 0.392 | 406.055 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Ferritin (PF00210, IPR008331): Ferritin-like domain GRP (PF07172, IPR010800): Glycine rich protein family Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
44 |
DES | interactor | 1 | 0 | 0 | Filament (PF00038, IPR001664): Intermediate filament protein Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region HAUS-augmin3 (PF14932, IPR032733): HAUS augmin-like complex subunit 3 |
45 |
DISC1 | interactor | 6 | 0.200 | 86.787 | HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper Mnd1 (PF03962, IPR005647): Mnd1 family TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Tropomyosin (PF00261, IPR000533): Tropomyosin UVR (PF02151, IPR001943): UvrB/uvrC motif CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding |
46 |
DLGAP1 | oncoprotein | 2 | 1.000 | 0 | Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein GKAP (PF03359, IPR005026): Guanylate-kinase-associated protein (GKAP) protein |
47 |
DNM1 | interactor | 10 | 0.389 | 52.539 | Dynamin_M (PF01031, IPR000375): Dynamin central region GED (PF02212, IPR003130, SM00302): Dynamin GTPase effector domain PH (PF00169, IPR001849, SM00233): PH domain Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family |
48 |
DNM2 | interactor | 20 | 0.263 | 342.267 | Dynamin_M (PF01031, IPR000375): Dynamin central region GED (PF02212, IPR003130, SM00302): Dynamin GTPase effector domain PH (PF00169, IPR001849, SM00233): PH domain Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family |
49 |
DSTN | interactor | 4 | 0 | 89.619 | Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein |
50 |
DTX3 | oncoprotein | 2 | 1.000 | 0 | zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
51 |
EED | suppressor | 42 | 0.371 | 405.305 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
52 |
EEF1A1 | suppressor | 51 | 0.362 | 877.056 | GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain |
53 |
EEF1G | protein found in more fusions | 29 | 0.439 | 80.567 | EF1G (PF00647, IPR001662): Elongation factor 1 gamma, conserved domain GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain GST_N (PF02798, IPR004045): Glutathione S-transferase, N-terminal domain SAPS (PF04499, IPR007587): SIT4 phosphatase-associated protein |
54 |
EEF2 | interactor | 30 | 0.547 | 76.434 | EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 EFG_II (PF14492, IPR009022): Elongation Factor G, domain II |
55 |
EPHB2 | suppressor | 2 | 0 | 0 | EGF_2 (PF07974, IPR013111): EGF-like domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) Ephrin_lbd (PF01404, IPR001090, SM00615): Ephrin receptor ligand binding domain cEGF (PF12662, IPR026823): Complement Clr-like EGF-like EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain |
56 |
EPN2 | interactor | 4 | 0.333 | 19.167 | ENTH (PF01417, IPR001026, SM00273): ENTH domain Pheromone (PF08015, IPR012597): Fungal mating-type pheromone UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif |
57 |
EPS15 | oncoprotein | 24 | 0.308 | 497.692 | Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391) EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand EF-hand_7 (PF13499, IPR011992): EF-hand domain pair |
58 |
EPS15L1 | oncoprotein | 8 | 0.321 | 40.414 | CALCOCO1 (PF07888, IPR012852): Calcium binding and coiled-coil domain (CALCOCO1) like Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand |
59 |
ESR1 | suppressor | 41 | 0.341 | 361.254 | Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal |
60 |
EWSR1 | oncoprotein | 58 | 0.313 | 1127.133 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head |
61 |
FBXW11 | interactor | 28 | 0.430 | 440.277 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like |
62 |
FCHSD2 | protein found in more fusions | 7 | 0.400 | 20.775 | Cortex-I_coil (PF09304, IPR015383): Cortexillin I, coiled coil DivIC (PF04977, IPR007060): Septum formation initiator FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain DUF4665 (PF15679, IPR031389): Domain of unknown function (DUF4665) Rit1_C (PF17184): Rit1 N-terminal domain |
63 |
FDPS | interactor | 5 | 0.800 | 2.790 | polyprenyl_synt (PF00348, IPR000092): Polyprenyl synthetase |
64 |
FN1 | oncoprotein | 66 | 0.271 | 1239.890 | fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) |
65 |
FNBP1 | oncoprotein | 6 | 0.500 | 3.114 | FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain HR1 (PF02185, IPR011072, SM00742): Hr1 repeat Laminin_II (PF06009, IPR010307): Laminin Domain II DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) SH3_9 (PF14604, IPR001452): Variant SH3 domain T3SSipB (PF16535, IPR032391): Type III cell invasion protein SipB |
66 |
FNBP4 | oncoprotein | 4 | 0.667 | 7.045 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal DUF1115 (PF06544, IPR010541): Protein of unknown function (DUF1115) Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator Pap_E4 (PF02711, IPR003861): E4 protein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 SMN (PF06003, IPR010304): Survival motor neuron protein (SMN) WW (PF00397, IPR001202, SM00456): WW domain DUF4637 (PF15470, IPR029174): Domain of unknown function (DUF4637) |
67 |
FUS | suppressor | 59 | 0.473 | 240.400 | Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others Limkain-b1 (PF11608, IPR024582): Limkain b1 FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head |
68 |
GAPDH | oncoprotein | 36 | 0.422 | 128.495 | Gp_dh_C (PF02800, IPR020829): Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N (PF00044, IPR020828, SM00846): Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain OstA (PF03968, IPR005653): OstA-like protein |
69 |
GAREM2 | interactor | 3 | 0.333 | 5.993 | SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) CABIT (PF12736, IPR025946): Cell-cycle sustaining, positive selection, |
70 |
GCC1 | interactor | 1 | 0 | 0 | DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC) GRIP (PF01465, IPR000237, SM00755): GRIP domain IFP_35_N (PF07334, IPR009938): Interferon-induced 35 kDa protein (IFP 35) N-terminus LPP (PF04728, IPR006817): Lipoprotein leucine-zipper DUF2335 (PF10097, IPR019284): Predicted membrane protein (DUF2335) Kinetocho_Slk19 (PF12709, IPR024312): Central kinetochore-associated Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit FAM184 (PF15665): Family with sequence similarity 184, A and B |
71 |
GCN1 | interactor | 15 | 0.438 | 10.680 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat HEAT (PF02985, IPR000357): HEAT repeat CLASP_N (PF12348, IPR024395): CLASP N terminal MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal TFCD_C (PF12612, IPR022577): Tubulin folding cofactor D C terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II |
72 |
GOLGA5 | oncoprotein | 3 | 0.667 | 15.072 | Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5 |
73 |
HDAC5 | protein found in more fusions | 29 | 0.444 | 49.631 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NOA36 (PF06524, IPR010531): NOA36 protein Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3 HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4 |
74 |
HDGF | interactor | 14 | 0.538 | 12.420 | PWWP (PF00855, IPR000313, SM00293): PWWP domain |
75 |
HIP1 | oncoprotein | 5 | 0.500 | 6.257 | ANTH (PF07651, IPR011417): ANTH domain Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Ribosomal_S2 (PF00318, IPR001865): Ribosomal protein S2 I_LWEQ (PF01608, IPR002558, SM00307): I/LWEQ domain HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 |
76 |
HNRNPA1 | interactor | 93 | 0.323 | 1909.892 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1 |
77 |
HNRNPA1L2 | interactor | 12 | 0.576 | 14.764 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1 |
78 |
HNRNPA2B1 | oncoprotein | 67 | 0.378 | 564.898 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
79 |
HNRNPAB | interactor | 50 | 0.408 | 414.709 | CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain GRP (PF07172, IPR010800): Glycine rich protein family NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2462 (PF09495, IPR019034): Protein of unknown function (DUF2462) |
80 |
HNRNPD | oncoprotein | 65 | 0.417 | 495.374 | CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Keratin_2_head (PF16208, IPR032444): Keratin type II head |
81 |
HNRNPDL | interactor | 44 | 0.578 | 99.355 | CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
82 |
HNRNPF | interactor | 49 | 0.481 | 151.019 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spot_14 (PF07084, IPR009786): Thyroid hormone-inducible hepatic protein Spot 14 zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger |
83 |
HNRNPH1 | oncoprotein | 59 | 0.468 | 445.399 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger |
84 |
HNRNPH2 | interactor | 38 | 0.563 | 73.810 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger |
85 |
HNRNPH3 | protein found in more fusions | 43 | 0.481 | 204.489 | Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
86 |
HNRNPK | oncoprotein | 64 | 0.381 | 709.178 | ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain KH_1 (PF00013, IPR004088, SM00322): KH domain |
87 |
HNRNPL | protein found in more fusions | 50 | 0.497 | 245.673 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dscam_C (PF12355, IPR021012): Down syndrome cell adhesion molecule C terminal RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
88 |
HNRNPU | interactor | 67 | 0.384 | 527.293 | CDC45 (PF02724, IPR003874): CDC45-like protein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SAP (PF02037, IPR003034, SM00513): SAP domain SPRY (PF00622, IPR003877, SM00449): SPRY domain AAA_33 (PF13671): AAA domain WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
89 |
HSD17B10 | interactor | 25 | 0.477 | 46.883 | adh_short (PF00106, IPR002198): short chain dehydrogenase |
90 |
HSPA5 | oncoprotein | 57 | 0.435 | 632.203 | HSP70 (PF00012, IPR013126): Hsp70 protein |
91 |
HSPA8 | oncoprotein | 48 | 0.371 | 420.067 | HSP70 (PF00012, IPR013126): Hsp70 protein |
92 |
ICAM1 | oncoprotein | 13 | 0.564 | 4.193 | Adhes-Ig_like (PF09085, IPR015169): Adhesion molecule, immunoglobulin-like C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain ICAM_N (PF03921, IPR013768): Intercellular adhesion molecule (ICAM), N-terminal domain Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain |
93 |
IFIT3 | interactor | 9 | 0.929 | 0.125 | TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_17 (PF13431): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat |
94 |
IGBP1 | interactor | 4 | 0.167 | 31.779 | TAP42 (PF04177, IPR007304): TAP42-like family |
95 |
IGSF8 | oncoprotein | 15 | 0.610 | 5.941 | V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain |
96 |
IL7R | interactor | 16 | 0.492 | 24.395 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain |
97 |
ITCH | interactor | 14 | 0.256 | 166.614 | C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) |
98 |
ITGA4 | interactor | 55 | 0.314 | 604.147 | FG-GAP (PF01839, IPR013517): FG-GAP repeat Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region Integrin_alpha2 (PF08441, IPR013649): Integrin alpha |
99 |
ITPA | protein found in more fusions | 4 | 1.000 | 0 | Ham1p_like (PF01725, IPR002637): Ham1 family |
100 |
ITSN2 | protein found in more fusions | 24 | 0.166 | 383.276 | C2 (PF00168, IPR000008, SM00239): C2 domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH3_2 (PF07653, IPR011511): Variant SH3 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) SH3_9 (PF14604, IPR001452): Variant SH3 domain MRP-S26 (PF14943, IPR026140): Mitochondrial ribosome subunit S26 VIR_N (PF15912, IPR031801): Virilizer, N-terminal PH_13 (PF16652, IPR001849): Pleckstrin homology domain |
101 |
KHDRBS1 | protein found in more fusions | 33 | 0.331 | 638.796 | KH_1 (PF00013, IPR004088, SM00322): KH domain Qua1 (PF16274, IPR032571): Qua1 domain Sam68-YY (PF16568, IPR032335): Tyrosine-rich domain of Sam68 |
102 |
KIF16B | interactor | 1 | 0 | 0 | DivIC (PF04977, IPR007060): Septum formation initiator NAD_binding_1 (PF00175, IPR001433): Oxidoreductase NAD-binding domain Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain DUF2721 (PF11026, IPR021279): Protein of unknown function (DUF2721) DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) VGCC_beta4Aa_N (PF12052, IPR000584): Voltage gated calcium channel subunit beta domain 4Aa N terminal Kinesin_assoc (PF16183, IPR032405): Kinesin-associated Yop-YscD_cpl (PF16697, IPR032030): Inner membrane component of T3SS, cytoplasmic domain |
103 |
KIF5A | interactor | 4 | 0.333 | 9.207 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724) Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein BLOC1_2 (PF10046, IPR019269): Biogenesis of lysosome-related organelles complex-1 subunit 2 Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding Microtub_bd (PF16796, IPR031852): Microtubule binding |
104 |
LIN28A | interactor | 3 | 0.667 | 0.268 | CSD (PF00313, IPR002059): 'Cold-shock' DNA-binding domain zf-CCHC (PF00098, IPR001878): Zinc knuckle zf-CCHC_6 (PF15288): Zinc knuckle |
105 |
LMO4 | interactor | 5 | 0.300 | 27.285 | LIM (PF00412, IPR001781, SM00132): LIM domain zf-dskA_traR (PF01258, IPR000962): Prokaryotic dksA/traR C4-type zinc finger |
106 |
MAP3K20 | protein found in more fusions | 7 | 0.400 | 31.793 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) DUF3552 (PF12072, IPR022711): Domain of unknown function (DUF3552) |
107 |
MAPK6 | oncoprotein | 11 | 0.222 | 110.589 | Pkinase (PF00069, IPR000719): Protein kinase domain |
108 |
MAPK8IP2 | interactor | 4 | 0.333 | 14.524 | BUD22 (PF09073, IPR015158): BUD22 CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal SH3_9 (PF14604, IPR001452): Variant SH3 domain |
109 |
MATR3 | protein found in more fusions | 45 | 0.518 | 202.533 | DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-U1 (PF06220, IPR013085, SM00451): U1 zinc finger Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAM60A (PF15396, IPR026065): Protein Family FAM60A |
110 |
MCM2 | oncoprotein | 60 | 0.393 | 499.868 | AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
111 |
MCM5 | oncoprotein | 28 | 0.492 | 84.982 | MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
112 |
MRPL20 | interactor | 2 | 0 | 10.355 | Herpes_UL49_5 (PF05702, IPR008647): Herpesvirus UL49.5 envelope/tegument protein Ribosomal_L20 (PF00453, IPR005813): Ribosomal protein L20 |
113 |
MRPS26 | interactor | 5 | 0.700 | 0.266 | MRP-S26 (PF14943, IPR026140): Mitochondrial ribosome subunit S26 |
114 |
MTUS2 | suppressor | 6 | 0.300 | 15.756 | DUF496 (PF04363, IPR007458): Protein of unknown function (DUF496) RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat FAM184 (PF15665): Family with sequence similarity 184, A and B |
115 |
NECAP2 | interactor | 6 | 0.800 | 14.004 | DUF1681 (PF07933, IPR012466): Protein of unknown function (DUF1681) |
116 |
NEDD8 | interactor | 39 | 0.566 | 140.442 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
117 |
NONO | oncoprotein | 39 | 0.364 | 295.275 | GvpL_GvpF (PF06386, IPR009430): Gas vesicle synthesis protein GvpL/GvpF NOPS (PF08075, IPR012975): NOPS (NUC059) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAS_7 (PF12860): PAS fold SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3 |
118 |
NTRK1 | oncoprotein | 92 | 0.211 | 3675.733 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
119 |
OBSL1 | interactor | 46 | 0.407 | 147.817 | BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain |
120 |
PACSIN3 | interactor | 12 | 0.218 | 94.382 | FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain GrpE (PF01025, IPR000740): GrpE SH3_9 (PF14604, IPR001452): Variant SH3 domain |
121 |
PAK3 | interactor | 3 | 1.000 | 0 | PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain Pkinase (PF00069, IPR000719): Protein kinase domain Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal |
122 |
PAN2 | interactor | 23 | 0.415 | 109.541 | RNase_T (PF00929, IPR013520): Exonuclease UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase WD40_like (PF17005, IPR031544): WD40-like domain |
123 |
PARK2 | suppressor | 31 | 0.430 | 93.619 | IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
124 |
PDCD6IP | interactor | 16 | 0.210 | 212.775 | BRO1 (PF03097, IPR004328, SM01041): BRO1-like domain MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c ALIX_LYPXL_bnd (PF13949, IPR025304): ALIX V-shaped domain binding to HIV |
125 |
PDE4D | oncoprotein | 5 | 0.167 | 65.150 | Na_trans_assoc (PF06512, IPR010526): Sodium ion transport-associated PDEase_I (PF00233, IPR002073): 3'5'-cyclic nucleotide phosphodiesterase |
126 |
PFDN5 | interactor | 5 | 0.100 | 44.257 | Prefoldin (PF02996, IPR004127): Prefoldin subunit UPF0693 (PF16088, IPR032143): UPF0693 family |
127 |
PGK1 | interactor | 22 | 0.558 | 66.919 | PGK (PF00162, IPR001576): Phosphoglycerate kinase |
128 |
PHB2 | interactor | 18 | 0.510 | 52.580 | DUF2605 (PF10792, IPR019728): Protein of unknown function (DUF2605) Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family |
129 |
PHF6 | suppressor | 9 | 0.806 | 2.170 | zf-HC5HC2H (PF13771): PHD-like zinc-binding domain YqfQ (PF14181, IPR025571): YqfQ-like protein |
130 |
PHGDH | interactor | 22 | 0.450 | 323.415 | 2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain |
131 |
PICALM | oncoprotein | 20 | 0.537 | 143.828 | ANTH (PF07651, IPR011417): ANTH domain |
132 |
PIK3AP1 | interactor | 2 | 1.000 | 0 | OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) DBB (PF14545, IPR017893): Dof, BCAP, and BANK (DBB) motif, |
133 |
PIK3C2B | interactor | 3 | 0.333 | 5.993 | C2 (PF00168, IPR000008, SM00239): C2 domain PI3K_C2 (PF00792, IPR002420, SM00142): Phosphoinositide 3-kinase C2 PI3K_rbd (PF00794, IPR000341, SM00144): PI3-kinase family, ras-binding domain PI3Ka (PF00613, IPR001263, SM00145): Phosphoinositide 3-kinase family, accessory domain (PIK domain) PX (PF00787, IPR001683, SM00312): PX domain PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase |
134 |
PIK3R1 | oncoprotein | 13 | 0.379 | 112.145 | RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain PI3K_P85_iSH2 (PF16454, IPR032498): Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain |
135 |
PLK1 | suppressor | 14 | 0.209 | 186.331 | Pkinase (PF00069, IPR000719): Protein kinase domain POLO_box (PF00659, IPR000959): POLO box duplicated region |
136 |
PPFIA2 | interactor | 2 | 0 | 0 | DUF745 (PF05335, IPR007999): Protein of unknown function (DUF745) HrpB7 (PF09486, IPR013392): Bacterial type III secretion protein (HrpB7) HWE_HK (PF07536, IPR011102, SM00911): HWE histidine kinase IFP_35_N (PF07334, IPR009938): Interferon-induced 35 kDa protein (IFP 35) N-terminus SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) SlyX (PF04102, IPR007236): SlyX TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein BLOC1_2 (PF10046, IPR019269): Biogenesis of lysosome-related organelles complex-1 subunit 2 CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour |
137 |
PPL | interactor | 4 | 0.333 | 32.393 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) Cortex-I_coil (PF09304, IPR015383): Cortexillin I, coiled coil DivIC (PF04977, IPR007060): Septum formation initiator MCU (PF04678, IPR006769): Mitochondrial calcium uniporter ZapB (PF06005, IPR009252): Cell division protein ZapB Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family FliT (PF05400, IPR008622): Flagellar protein FliT M (PF02370, IPR003345): M protein repeat Mnd1 (PF03962, IPR005647): Mnd1 family Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain Spectrin (PF00435, IPR002017): Spectrin repeat Plectin (PF00681, IPR001101, SM00250): Plectin repeat TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit DUF4140 (PF13600, IPR025554): N-terminal domain of unknown function (DUF4140) DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472) |
138 |
PREX1 | oncoprotein | 1 | 0 | 0 | DEP (PF00610, IPR000591, SM00049): Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) PH (PF00169, IPR001849, SM00233): PH domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain |
139 |
PROSC | interactor | 7 | 0.714 | 1.282 | Ala_racemase_N (PF01168, IPR001608): Alanine racemase, N-terminal domain |
140 |
PTBP1 | oncoprotein | 45 | 0.551 | 108.717 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
141 |
PUF60 | protein found in more fusions | 25 | 0.630 | 21.869 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Titin_Z (PF09042, IPR015129): Titin Z TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence |
142 |
RAB10 | oncoprotein | 11 | 0.436 | 8.293 | Ras (PF00071, IPR001806, SM00173): Ras family |
143 |
RAB11FIP2 | protein found in more fusions | 5 | 0.333 | 13.228 | C2 (PF00168, IPR000008, SM00239): C2 domain RBD-FIP (PF09457, IPR019018): FIP domain |
144 |
RAB1A | oncoprotein | 17 | 0.279 | 240.378 | Ras (PF00071, IPR001806, SM00173): Ras family |
145 |
RAB5A | oncoprotein | 9 | 0.222 | 107.092 | Ras (PF00071, IPR001806, SM00173): Ras family |
146 |
RAB7A | suppressor | 19 | 0.415 | 101.971 | Ras (PF00071, IPR001806, SM00173): Ras family |
147 |
RABEP1 | oncoprotein | 9 | 0.214 | 79.280 | Fib_succ_major (PF09603, IPR011871): Fibrobacter succinogenes major domain (Fib_succ_major) Rab5-bind (PF09311, IPR015390): Rabaptin-like protein Rabaptin (PF03528, IPR018514): Rabaptin |
148 |
RAD18 | interactor | 7 | 0.267 | 55.249 | PhoU_div (PF01865, IPR018445): Protein of unknown function DUF47 SAP (PF02037, IPR003034, SM00513): SAP domain zf-CpG_bind_C (PF12269, IPR022056): CpG binding protein zinc finger C terminal domain zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) |
149 |
RAD21 | oncoprotein | 23 | 0.383 | 260.643 | Rad21_Rec8 (PF04824, IPR006909): Conserved region of Rad21 / Rec8 like protein Rad21_Rec8_N (PF04825, IPR006910): N terminus of Rad21 / Rec8 like protein FAM176 (PF14851): FAM176 family WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
150 |
RAI14 | interactor | 6 | 0.400 | 41.475 | Ank (PF00023, IPR002110, SM00248): Ankyrin repeat Fez1 (PF06818): Fez1 FliJ (PF02050, IPR012823): Flagellar FliJ protein Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region DUF2408 (PF10303, IPR018810): Protein of unknown function (DUF2408) TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding MscS_porin (PF12795, IPR024393): Mechanosensitive ion channel porin domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) AAA_13 (PF13166, IPR026866): AAA domain Ank_5 (PF13857): Ankyrin repeats (many copies) PKcGMP_CC (PF16808, IPR031831): Coiled-coil N-terminus of cGMP-dependent protein kinase |
151 |
REPS1 | protein found in more fusions | 9 | 0.429 | 77.958 | Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator MCLC (PF05934, IPR009231): Mid-1-related chloride channel (MCLC) DUF3123 (PF11321, IPR021470): Protein of unknown function (DUF3123) EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand |
152 |
RNASEH2A | interactor | 3 | 0.333 | 16.430 | RNase_HII (PF01351, IPR024567): Ribonuclease HII |
153 |
RNF2 | interactor | 35 | 0.296 | 218.529 | zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like |
154 |
RNF40 | protein found in more fusions | 6 | 0.400 | 25.860 | BRE1 (PF08647, IPR013956): BRE1 E3 ubiquitin ligase DUF745 (PF05335, IPR007999): Protein of unknown function (DUF745) ZapB (PF06005, IPR009252): Cell division protein ZapB EzrA (PF06160, IPR010379): Septation ring formation regulator, EzrA FlgN (PF05130, IPR007809): FlgN protein Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat SpoIIE (PF07228, IPR001932): Stage II sporulation protein E (SpoIIE) T5orf172 (PF10544, IPR018306, SM00974): T5orf172 domain XhlA (PF10779, IPR019715): Haemolysin XhlA ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) KASH_CCD (PF14662, IPR028168): Coiled-coil region of CCDC155 or KASH Snapin_Pallidin (PF14712, IPR028119): Snapin/Pallidin zf-RING_6 (PF14835): zf-RING of BARD1-type protein |
155 |
RPA1 | suppressor | 54 | 0.366 | 716.322 | Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain |
156 |
RPA2 | oncoprotein | 45 | 0.433 | 385.265 | RPA_C (PF08784, IPR014892): Replication protein A C terminal tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2 |
157 |
RPA3 | interactor | 43 | 0.444 | 212.611 | Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3 |
158 |
RPLP2 | protein found in more fusions | 26 | 0.503 | 42.244 | Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein |
159 |
RPS13 | interactor | 26 | 0.391 | 71.196 | Ribosomal_S13_N (PF08069, IPR012606): Ribosomal S13/S15 N-terminal domain Ribosomal_S15 (PF00312, IPR000589): Ribosomal protein S15 |
160 |
RPS28 | interactor | 19 | 0.538 | 20.808 | Ribosomal_S28e (PF01200, IPR000289): Ribosomal protein S28e |
161 |
RPS6KA5 | interactor | 6 | 0.467 | 33.309 | Choline_kinase (PF01633): Choline/ethanolamine kinase Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein |
162 |
RSU1 | interactor | 2 | 1.000 | 0 | LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat |
163 |
SCAMP1 | interactor | 5 | 0.500 | 10.335 | SCAMP (PF04144, IPR007273): SCAMP family DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) |
164 |
SCARNA22 | interactor | 18 | 0.654 | 7.181 | NA |
165 |
SCOC | interactor | 2 | 0 | 20.881 | DUF2205 (PF10224, IPR019357): Predicted coiled-coil protein (DUF2205) |
166 |
SETD3 | interactor | 3 | 0.333 | 19.690 | Pertussis_S2S3 (PF02918, IPR020063): Pertussis toxin, subunit 2 and 3, C-terminal domain Rubis-subs-bind (PF09273, IPR015353): Rubisco LSMT substrate-binding SET (PF00856, IPR001214, SM00317): SET domain Transposase_1 (PF01359, IPR001888): Transposase (partial DDE domain) |
167 |
SF3A2 | interactor | 20 | 0.574 | 24.992 | Cytadhesin_P30 (PF07271, IPR009896): Cytadhesin P30/P32 PRP4 (PF08799, IPR014906): pre-mRNA processing factor 4 (PRP4) like Totivirus_coat (PF05518, IPR008871): Totivirus coat protein zf-met (PF12874): Zinc-finger of C2H2 type ARL6IP6 (PF15062, IPR029383): Haemopoietic lineage transmembrane helix SF3A2 (PF16835, IPR031781): Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) |
168 |
SF3B4 | interactor | 16 | 0.558 | 181.495 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
169 |
SFPQ | oncoprotein | 46 | 0.386 | 224.408 | GRP (PF07172, IPR010800): Glycine rich protein family Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein NOPS (PF08075, IPR012975): NOPS (NUC059) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit PAT1 (PF09770, IPR019167): Topoisomerase II-associated protein PAT1 CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance |
170 |
SGIP1 | interactor | 3 | 1.000 | 0 | muHD (PF10291, IPR018808): Muniscin C-terminal mu homology domain |
171 |
SH3GL2 | oncoprotein | 10 | 0.528 | 12.322 | BAR (PF03114, IPR004148, SM00721): BAR domain SH3_2 (PF07653, IPR011511): Variant SH3 domain |
172 |
SH3KBP1 | protein found in more fusions | 27 | 0.191 | 480.506 | Tmemb_cc2 (PF10267, IPR019394): Predicted transmembrane and coiled-coil 2 protein SH3_9 (PF14604, IPR001452): Variant SH3 domain |
173 |
SIRT7 | interactor | 29 | 0.278 | 184.273 | DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563) SIR2 (PF02146, IPR003000): Sir2 family |
174 |
SKIV2L | interactor | 4 | 0.500 | 13.576 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase DSHCT (PF08148, IPR012961, SM01142): DSHCT (NUC185) domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain DUF3516 (PF12029, IPR021904): Domain of unknown function (DUF3516) rRNA_proc-arch (PF13234, IPR025696): rRNA-processing arch domain |
175 |
SMARCC2 | interactor | 13 | 0.359 | 96.988 | GHMP_kinases_N (PF00288, IPR006204): GHMP kinases N terminal domain SWIRM (PF04433, IPR007526): SWIRM domain DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1 SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal |
176 |
SMURF1 | interactor | 22 | 0.495 | 18.910 | C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) |
177 |
SNAP23 | interactor | 8 | 0.238 | 178.058 | DivIC (PF04977, IPR007060): Septum formation initiator DUF16 (PF01519, IPR002862): Protein of unknown function DUF16 SNAP-25 (PF00835, IPR000928): SNAP-25 family DUF5089 (PF17002, IPR031547): Domain of unknown function (DUF5089) |
178 |
SNAP25 | interactor | 2 | 1.000 | 0 | SNAP-25 (PF00835, IPR000928): SNAP-25 family Use1 (PF09753, IPR019150): Membrane fusion protein Use1 |
179 |
SNW1 | protein found in more fusions | 47 | 0.384 | 422.584 | SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term SIR4_SID (PF16991, IPR031556): Sir4 SID domain |
180 |
SNX5 | oncoprotein | 3 | 0.667 | 2.131 | PX (PF00787, IPR001683, SM00312): PX domain Vps5 (PF09325, IPR015404): Vps5 C terminal like |
181 |
SOS1 | oncoprotein | 6 | 0.733 | 6.821 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 PH (PF00169, IPR001849, SM00233): PH domain RasGEF (PF00617, IPR001895, SM00147): RasGEF domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain RasGEF_N (PF00618, IPR000651, SM00229): RasGEF N-terminal motif |
182 |
SPDL1 | protein found in more fusions | 3 | 0 | 5.052 | Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein DUF2911 (PF11138, IPR021314): Protein of unknown function (DUF2911) ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II |
183 |
SPRY2 | suppressor | 7 | 0.467 | 42.767 | KAR9 (PF08580, IPR013889): Yeast cortical protein KAR9 Sprouty (PF05210, IPR007875): Sprouty protein (Spry) |
184 |
SREK1 | protein found in more fusions | 15 | 0.604 | 33.566 | Ureide_permease (PF07168, IPR009834): Ureide permease RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RP-C_C (PF11800, IPR021760): Replication protein C C-terminal region PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) BRD4_CDT (PF17105, IPR031354): C-terminal domain of bromodomain protein 4 |
185 |
SRPK2 | oncoprotein | 22 | 0.471 | 183.278 | DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387) Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator Pkinase (PF00069, IPR000719): Protein kinase domain S-antigen (PF05756, IPR008825): S-antigen protein DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) |
186 |
SRRM2 | interactor | 36 | 0.476 | 193.761 | cwf21 (PF08312, IPR013170, SM01115): cwf21 domain DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Pap_E4 (PF02711, IPR003861): E4 protein RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 CTD (PF12815, IPR024945, SM01104): Spt5 C-terminal nonapeptide repeat binding Spt4 DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614) |
187 |
STAU1 | protein found in more fusions | 43 | 0.384 | 402.200 | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Staufen_C (PF16482, IPR032478): Staufen C-terminal domain |
188 |
STK24 | interactor | 5 | 0.333 | 3.095 | DUF1241 (PF06840, IPR009652): Protein of unknown function (DUF1241) Pkinase (PF00069, IPR000719): Protein kinase domain |
189 |
STON2 | interactor | 9 | 0.722 | 25.418 | Adap_comp_sub (PF00928, IPR008968): Adaptor complexes medium subunit family Stonin2_N (PF12016, IPR022699): Stonin 2 |
190 |
SYNCRIP | interactor | 58 | 0.386 | 424.006 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1 |
191 |
SYNJ1 | interactor | 7 | 0.524 | 7.852 | DUF1866 (PF08952, IPR015047, SM01165): Domain of unknown function (DUF1866) Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family Syja_N (PF02383, IPR002013): SacI homology domain YppG (PF14179, IPR025555): YppG-like protein |
192 |
SYNJ2 | interactor | 3 | 1.000 | 0 | DUF1866 (PF08952, IPR015047, SM01165): Domain of unknown function (DUF1866) Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family Syja_N (PF02383, IPR002013): SacI homology domain TSKS (PF15358, IPR028214): Testis-specific serine kinase substrate |
193 |
TARDBP | interactor | 44 | 0.543 | 90.946 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
194 |
TFG | oncoprotein | 22 | 0.438 | 347.191 | ARS2 (PF04959, IPR007042): Arsenite-resistance protein 2 MucBP (PF06458, IPR009459): MucBP domain PB1 (PF00564, IPR000270, SM00666): PB1 domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit |
195 |
TK1 | oncoprotein | 9 | 0.393 | 73.980 | TK (PF00265, IPR001267, SM00203): Thymidine kinase |
196 |
TOP1 | oncoprotein | 30 | 0.517 | 46.849 | DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) Topoisom_I (PF01028, IPR013500): Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N (PF02919, IPR008336): Eukaryotic DNA topoisomerase I, DNA binding fragment MCM_bind (PF09739, IPR019140): Mini-chromosome maintenance replisome factor Sox_N (PF12444, IPR022151): Sox developmental protein N terminal Topo_C_assoc (PF14370, IPR025834): C-terminal topoisomerase domain DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614) TonB_N (PF16031): TonB N-terminal region |
197 |
TP63 | suppressor | 13 | 0.470 | 12.032 | Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) |
198 |
TRIM8 | interactor | 4 | 0.667 | 0.771 | dCache_2 (PF08269, IPR004010, SM01049): Cache domain CASP_C (PF08172, IPR012955): CASP C terminal zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger Zn_ribbon_recom (PF13408, IPR025827): Recombinase zinc beta ribbon domain zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING |
199 |
TSG101 | suppressor | 12 | 0.345 | 85.017 | APG6 (PF04111, IPR007243): Autophagy protein Apg6 Laminin_II (PF06009, IPR010307): Laminin Domain II UEV (PF05743, IPR008883): UEV domain Vps23_core (PF09454, IPR017916): Vps23 core domain |
200 |
TTC37 | interactor | 7 | 0.476 | 67.128 | DUF982 (PF06169, IPR010385): Protein of unknown function (DUF982) Sel1 (PF08238, IPR006597, SM00671): Sel1 repeat TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat TPR_3 (PF07720, IPR011716): Tetratricopeptide repeat Vps39_1 (PF10366, IPR019452): Vacuolar sorting protein 39 domain 1 Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_15 (PF13429): Tetratricopeptide repeat TPR_17 (PF13431): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat Retrotran_gag_2 (PF14223): gag-polypeptide of LTR copia-type TPR_19 (PF14559): Tetratricopeptide repeat |
201 |
U2AF2 | protein found in more fusions | 53 | 0.477 | 181.616 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein |
202 |
UBC | protein found in more fusions | 64 | 0.291 | 1373.258 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
203 |
UBE2K | interactor | 8 | 0.250 | 197.925 | UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
204 |
UBE2N | protein found in more fusions | 9 | 0.429 | 8.850 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
205 |
UBQLN2 | protein found in more fusions | 13 | 0.394 | 71.156 | Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family SUZ (PF12752, IPR024771): SUZ domain Fur_reg_FbpB (PF13040, IPR025004): Fur-regulated basic protein B |
206 |
UNC119 | interactor | 7 | 0.333 | 30.333 | GMP_PDE_delta (PF05351, IPR008015): GMP-PDE, delta subunit |
207 |
UQCRC2 | oncoprotein | 12 | 0.288 | 64.207 | Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16) Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain |
208 |
USP37 | interactor | 11 | 0.578 | 13.295 | UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase UCH_N (PF16674, IPR032069): N-terminal of ubiquitin carboxyl-terminal hydrolase 37 |
209 |
VCAM1 | interactor | 46 | 0.302 | 361.662 | C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain |
210 |
VHL | suppressor | 25 | 0.717 | 114.398 | Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) VHL (PF01847, IPR022772): VHL beta domain VHL_C (PF17211): VHL box domain |
211 |
WAS | oncoprotein | 9 | 0.389 | 20.060 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain WH1 (PF00568, IPR000697, SM00461): WH1 domain WH2 (PF02205, IPR003124, SM00246): WH2 motif PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
212 |
WASL | interactor | 9 | 0.222 | 84.415 | Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain WH1 (PF00568, IPR000697, SM00461): WH1 domain WH2 (PF02205, IPR003124, SM00246): WH2 motif RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein Caskin-Pro-rich (PF16907): Proline rich region of Caskin proteins |
213 |
WBP11 | interactor | 8 | 0.571 | 65.949 | BUD22 (PF09073, IPR015158): BUD22 Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region SspB (PF04386, IPR007481): Stringent starvation protein B Wbp11 (PF09429, IPR019007): WW domain binding protein 11 ABC_trans_N (PF14510, IPR029481): ABC-transporter extracellular N-terminal |
214 |
WWOX | suppressor | 18 | 0.366 | 66.446 | adh_short (PF00106, IPR002198): short chain dehydrogenase WW (PF00397, IPR001202, SM00456): WW domain |
215 |
YWHAE | oncoprotein | 35 | 0.326 | 370.290 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
216 |
ZBTB1 | interactor | 6 | 0.333 | 47.920 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-BED (PF02892, IPR003656, SM00614): BED zinc finger zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies) zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger |
217 |
ZFAND6 | interactor | 3 | 0.667 | 0.189 | zf-A20 (PF01754, IPR002653, SM00259): A20-like zinc finger zf-AN1 (PF01428, IPR000058, SM00154): AN1-like Zinc finger |
218 |
ZFPM2 | interactor | 1 | 0 | 0 | LIM (PF00412, IPR001781, SM00132): LIM domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-met (PF12874): Zinc-finger of C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_3 (PF13878, IPR028005): zinc-finger of acetyl-transferase ESCO zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain |