Find Fusion Network

Visualization interactions

Powered by Cytoscape Web for: parental proteins CUL4A, SIL1 (from a repository: Fri Aug 9 11:45:13 2019)

Examples AFF1 MLL ACTN4 + MLLAFF1 + MLLALK + MSNALK + TFGALK + TPM3ALK + TPM4ASXL2 + KAT6AATF1 + FUSBCR + ABL1BCR + FGFR1CCND1 + TACSTD2CD74 + ROS1CDK6 + MLLCOL1A1 + PDGFBCREB3L2 + PPARGCREB3L2 + FUSCREBBP + KAT6ADAZAP1 + MEF2DELL + MLLEPS15 + MLLERG + EWSR1ERG + FUSERG + TMPRSS2ETV5 + TMPRSS2ETV6 + ABL1ETV6 + NTRK3ETV6 + PAX5EWSR1 + FLI1EWSR1 + WT1FOXO1 + PAX3FOXP1 + PAX5FRYL + MLLGAS7 + MLLGMPS + MLLGOLGA5 + RETHOOK3 + RETHOXC13 + NUP98HOXD13 + NUP98MECOM + RUNX1MKL1 + RBM15MLL + MLLT1MLL + MLLT4MLL + MLLT10MLL + PICALMMLLT10 + PICALMNCOA1 + PAX3NIN + PDGFRBNPM1 + RARANRG1 + ODZ4NTRK1 + TFGNUMA1 + RARANUP98 + PHF23PAX5 + ZNF521PBX1 + TCF3RET + TRIM27ROS1 + SLC34A2PML + RARAPRKAR1A + RARAPRKAR1A + RETRUNX1 + RUNX1T1RUNX1 + SH3D19	Cytoscape Web will replace the contents your graph	PPI Properties: Click on nodes or edges
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Statistics and Network structure information

Statistic of PPI Value(s) The number of interactors (fusion and proteins) 289 The number (and %) of the onco-proteins 81 (28.03 %) The number (and %) of the tumor suppressors 32 (11.07 %) Total number of binary PPIs (saturation %) 3225 (7.75 %) The number (and %) of affected PPIs 289 (8.96 %) The number of possible different fusions 44 PPI diameter 3 PPI radius 2 The average degree of PPI 21.792 Assortativity coefficient -0.2996 The network average Clustering coefficient 0.582 The number (and %) of a zero Clustering coefficients 9 (3.11 %) The number (and %) of a zero Betweenness Centrality 43 (14.88 %)

ACTIVE INTERACTORS

List of the fusions
PPI for parental proteins: CUL4A,SIL1	All fusions
Proteins found in more fusions	GRK5 (see 2 fusions); NPM1 (see 1 fusions); DCAF1 (see 1 fusions); COMMD1 (see 1 fusions); CUL1 (see 3 fusions); LGALS3BP (see 2 fusions); PCBD1 (see 1 fusions); RPS18/TUBG1 (see 1 fusions); UBQLN1 (see 2 fusions); EWSR1 (see 1 fusions); PRDX1 (see 1 fusions); SAMHD1 (see 1 fusions); PCNA (see 1 fusions); DDX5 (see 1 fusions); RPLP2 (see 1 fusions); ARIH1 (see 4 fusions); CUL4A (see 4 fusions); VCP (see 4 fusions); HSP90AA1 (see 6 fusions); PRMT5 (see 1 fusions); TLE2 (see 2 fusions); HSP90AB1 (see 3 fusions); COPS5/HNRNPH3 (see 3 fusions); HNRNPD (see 1 fusions); NF2 (see 1 fusions); TUBA1B/TUBA1C (see 11 fusions); HSP90AA1/BAG4 (see 1 fusions); DDB1 (see 4 fusions); NCL (see 4 fusions); HSPA8/HSPD1 (see 1 fusions); TUBG1 (see 1 fusions); EEF1A1 (see 6 fusions); CUL3 (see 1 fusions); MYC (see 2 fusions); UBE2E3 (see 5 fusions); COPS5 (see 1 fusions); UBC (see 7 fusions); HSP90AA1/TUBB (see 1 fusions); TP53 (see 3 fusions); PABPC1 (see 3 fusions); NFKB1 (see 2 fusions); MCM2 (see 1 fusions); RPTOR (see 3 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	CUL4A	parental protein	279	0.072	35920.040	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
2	SIL1	parental protein	10	0.156	115.345	Fes1 (PF08609, IPR013918): Nucleotide exchange factor Fes1 HEAT (PF02985, IPR000357): HEAT repeat RTTN_N (PF14726, IPR029249): Rotatin, an armadillo repeat protein, centriole functioning DUF4704 (PF15787, IPR031570): Domain of unknown function (DUF4704)
3	ABCA10	interactor	2	1.000	0	ABC_tran (PF00005, IPR003439): ABC transporter DUF258 (PF03193, IPR004881): Protein of unknown function, DUF258 Wzy_C (PF04932, IPR007016): O-Antigen ligase ABC2_membrane_3 (PF12698): ABC-2 family transporter protein AAA_21 (PF13304, IPR003959): AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C (PF13558): Putative exonuclease SbcCD, C subunit DUF4162 (PF13732, IPR025302): Domain of unknown function (DUF4162) Cadherin_C_2 (PF16492, IPR032455): Cadherin cytoplasmic C-terminal
4	ABCE1	interactor	16	0.257	90.794	ABC_tran (PF00005, IPR003439): ABC transporter Fer4 (PF00037, IPR001450): 4Fe-4S binding domain RLI (PF04068, IPR007209): Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain Fer4_7 (PF12838, IPR001450): 4Fe-4S dicluster domain AAA_29 (PF13555): P-loop containing region of AAA domain
5	AK9	oncoprotein	2	1.000	0	ADK (PF00406, IPR000850): Adenylate kinase Cwf_Cwc_15 (PF04889, IPR006973): Cwf15/Cwc15 cell cycle control protein GN3L_Grn1 (PF08701, IPR014813): GNL3L/Grn1 putative GTPase Josephin (PF02099, IPR006155): Josephin MAS20 (PF02064, IPR002056): MAS20 protein import receptor YHS (PF04945, IPR007029): YHS domain RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31 DUF3508 (PF12018, IPR021897): Domain of unknown function (DUF3508) AAA_14 (PF13173): AAA domain AAA_16 (PF13191): AAA ATPase domain AAA_17 (PF13207): AAA domain AAA_18 (PF13238): AAA domain
6	AMBRA1	interactor	18	0.405	100.623	Acyl_CoA_thio (PF02551, IPR025652): Acyl-CoA thioesterase eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Spt20 (PF12090, IPR021950): Spt20 family ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
7	ANAPC5	interactor	3	0.667	0.333	TPR_4 (PF07721, IPR011717): Tetratricopeptide repeat ANAPC5 (PF12862, IPR026000): Anaphase-promoting complex subunit 5 TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat
8	ARIH1	protein found in more fusions	8	0.762	1.264	CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain Med14 (PF08638, IPR013947): Mediator complex subunit MED14 zinc_ribbon_2 (PF13240, IPR026870): zinc-ribbon domain zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain
9	ASB4	interactor	7	0.524	1.887	Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies) SOCS_box (PF07525, IPR001496): SOCS box
10	BAG4	protein found in more fusions	13	0.859	0.998	BAG (PF02179, IPR003103, SM00264): BAG domain DMP12 (PF16779, IPR031891): DNA-mimic protein
11	BANF1	interactor	11	0.378	12.328	BAF (PF02961, IPR004122, SM01023): Barrier to autointegration factor
12	BRWD1	interactor	5	0.900	0.154	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain SEEEED (PF14797, IPR029394): Serine-rich region of AP3B1, clathrin-adaptor complex
13	BTRC	oncoprotein	34	0.299	351.480	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like
14	C1QBP	interactor	25	0.523	30.953	MAM33 (PF02330, IPR003428): Mitochondrial glycoprotein DUF3053 (PF11254, IPR021413): Protein of unknown function (DUF3053)
15	CA2	interactor	6	0.867	0.589	Carb_anhydrase (PF00194, IPR001148, SM01057): Eukaryotic-type carbonic anhydrase
16	CAND1	interactor	118	0.186	1616.939	Adaptin_N (PF01602, IPR002553): Adaptin N terminal region DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981) HEAT (PF02985, IPR000357): HEAT repeat TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20) RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
17	CARNMT1	interactor	2	1.000	0	N2227 (PF07942, IPR012901): N2227-like protein RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
18	CAST	oncoprotein	3	1.000	0	Band_3_cyto (PF07565, IPR013769): Band 3 cytoplasmic domain Calpain_inhib (PF00748, IPR001259): Calpain inhibitor Maf_N (PF08383, IPR013592): Maf N-terminal region
19	CCND3	oncoprotein	7	0.286	27.718	Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
20	CCNG1	oncoprotein	4	1.000	0	Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
21	CCT5	interactor	23	0.289	89.531	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
22	CDKN1A	suppressor	30	0.352	186.629	CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor
23	CDKN1B	suppressor	16	0.592	77.050	CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor Multi-haem_cyto (PF13447): Seven times multi-haem cytochrome CxxCH
24	CDT1	oncoprotein	13	0.500	17.083	CDT1 (PF08839, IPR014939, SM01075): DNA replication factor CDT1 like CDT1_C (PF16679, IPR032054): DNA replication factor Cdt1 C-terminal domain
25	CDY2A	interactor	1	0	0	Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain ECH_1 (PF00378, IPR001753): Enoyl-CoA hydratase/isomerase Mrr_cat (PF04471, IPR007560): Restriction endonuclease DUF2607 (PF10795, IPR019731): Protein of unknown function (DUF2607)
26	CDY2B	interactor	1	0	0	Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain ECH_1 (PF00378, IPR001753): Enoyl-CoA hydratase/isomerase Mrr_cat (PF04471, IPR007560): Restriction endonuclease DUF2607 (PF10795, IPR019731): Protein of unknown function (DUF2607)
27	CENPA	interactor	12	0.364	9.351	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
28	CHEK1	suppressor	13	0.615	5.357	Pkinase (PF00069, IPR000719): Protein kinase domain
29	CHEK2	suppressor	9	0.571	3.330	FHA (PF00498, IPR000253, SM00240): FHA domain Pkinase (PF00069, IPR000719): Protein kinase domain
30	CLCN1	interactor	4	1.000	0	CBS (PF00571, IPR000644, SM00116): CBS domain Voltage_CLC (PF00654, IPR001807): Voltage gated chloride channel
31	COMMD1	protein found in more fusions	9	0.679	2.766	COMMD1_N (PF17221): COMMD1 N-terminal domain COMM_domain (PF07258): COMM domain
32	COPS2	suppressor	33	0.492	111.466	YozE_SAM_like (PF06855, IPR023089): YozE SAM-like fold TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat DUF2087 (PF09860, IPR018656): Uncharacterized protein conserved in bacteria (DUF2087) PCI (PF01399, IPR000717, SM00088): PCI domain TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat
33	COPS3	interactor	38	0.498	99.256	RasGEF (PF00617, IPR001895, SM00147): RasGEF domain TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat PCI (PF01399, IPR000717, SM00088): PCI domain
34	COPS4	interactor	37	0.514	97.337	DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) PCI (PF01399, IPR000717, SM00088): PCI domain TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_14 (PF13428): Tetratricopeptide repeat
35	COPS5	protein found in more fusions	155	0.153	3868.277	JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
36	COPS6	interactor	109	0.194	1699.064	DUF320 (PF03777, IPR005528): Small secreted domain (DUF320) JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function
37	COPS7A	interactor	33	0.545	79.610	PCI (PF01399, IPR000717, SM00088): PCI domain
38	COPS7B	interactor	22	0.831	6.940	PCI (PF01399, IPR000717, SM00088): PCI domain
39	COPS8	interactor	27	0.680	28.607	CSN8_PSD8_EIF3K (PF10075): CSN8/PSMD8/EIF3K family
40	COPS9	interactor	15	0.829	4.198	MYEOV2 (PF15004, IPR029391): Myeloma-overexpressed-like
41	CRBN	interactor	12	0.576	11.308	LON_substr_bdg (PF02190, IPR003111, SM00464): ATP-dependent protease La (LON) substrate-binding domain Yippee-Mis18 (PF03226, IPR004910): Yippee zinc-binding/DNA-binding /Mis18, centromere assembly
42	CSN1S1	interactor	4	1.000	0	zf-Tim10_DDP (PF02953, IPR004217): Tim10/DDP family zinc finger Gly-rich_Ago1 (PF12764, IPR024357): Glycine-rich region of argonaut
43	CTNNB1	oncoprotein	28	0.310	98.529	Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361) HEAT_EZ (PF13513): HEAT-like repeat
44	CUL1	suppressor	154	0.147	3680.600	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
45	CUL3	protein found in more fusions	153	0.144	4325.314	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
46	CUL4B	oncoprotein	152	0.130	4600.707	Cullin (PF00888, IPR001373, SM00182): Cullin family EBP50_C (PF09007, IPR015098): EBP50, C-terminal Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain PG_binding_4 (PF12229, IPR022029): Putative peptidoglycan binding domain MDFI (PF15316, IPR026134): MyoD family inhibitor
47	CUL5	suppressor	133	0.170	2389.752	Cullin (PF00888, IPR001373, SM00182): Cullin family GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
48	DAB2IP	suppressor	5	0.900	0.033	C2 (PF00168, IPR000008, SM00239): C2 domain PH_2 (PF08458, IPR013666): Plant pleckstrin homology-like region RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase DUF3498 (PF12004, IPR021887): Domain of unknown function (DUF3498)
49	DCAF1	protein found in more fusions	32	0.432	95.478	DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) LisH (PF08513, IPR013720, SM00667): LisH ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
50	DCAF10	interactor	6	1.000	0	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
51	DCAF11	interactor	15	0.848	2.517	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
52	DCAF12	interactor	5	1.000	0	ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain WD40_like (PF17005, IPR031544): WD40-like domain
53	DCAF12L2	interactor	2	1.000	0	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
54	DCAF15	interactor	3	1.000	0	DCAF15_WD40 (PF14939, IPR032734): DDB1-and CUL4-substrate receptor 15, WD repeat
55	DCAF16	interactor	6	1.000	0	DCA16 (PF15349, IPR028216): DDB1- and CUL4-associated factor 16
56	DCAF17	interactor	5	1.000	0	DCAF17 (PF15802, IPR031620): DDB1- and CUL4-associated factor 17
57	DCAF4	interactor	9	0.889	1.002	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain DUF4221 (PF13970, IPR025316): Domain of unknown function (DUF4221)
58	DCAF4L1	interactor	3	1.000	0	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat zf-CHC2 (PF01807, IPR002694): CHC2 zinc finger ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
59	DCAF4L2	interactor	3	1.000	0	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
60	DCAF5	interactor	8	0.393	78.286	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat DUF2634 (PF10934, IPR020288): Protein of unknown function (DUF2634) IMUP (PF15761, IPR026621): Immortalisation up-regulated protein
61	DCAF6	interactor	6	1.000	0	Herpes_pp85 (PF04637, IPR006731): Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat DUF3408 (PF11888, IPR021823): Protein of unknown function (DUF3408) ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain ATAD4 (PF15321, IPR028237): ATPase family AAA domain containing 4 MRI (PF15325, IPR028278): Modulator of retrovirus infection WD40_like (PF17005, IPR031544): WD40-like domain
62	DCAF7	interactor	7	0.667	0.846	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
63	DCAF8	interactor	14	0.703	6.759	DUF1635 (PF07795, IPR012862): Protein of unknown function (DUF1635) WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain DUF4661 (PF15576, IPR029073): Domain of unknown function (DUF4661)
64	DCST1	interactor	1	0	0	DC_STAMP (PF07782, IPR012858): DC-STAMP-like protein zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
65	DCUN1D1	interactor	89	0.250	717.962	Cullin_binding (PF03556, IPR005176): Cullin binding UBA_4 (PF14555): UBA-like domain
66	DCUN1D2	interactor	9	0.889	0.792	Cullin_binding (PF03556, IPR005176): Cullin binding UBA_4 (PF14555): UBA-like domain
67	DCUN1D3	suppressor	8	0.893	0.459	Cullin_binding (PF03556, IPR005176): Cullin binding
68	DCUN1D4	interactor	8	0.893	0.459	Cullin_binding (PF03556, IPR005176): Cullin binding
69	DCUN1D5	interactor	9	0.889	0.681	Cullin_binding (PF03556, IPR005176): Cullin binding
70	DDA1	interactor	37	0.324	210.425	DDA1 (PF10172, IPR018276): Det1 complexing ubiquitin ligase
71	DDB1	protein found in more fusions	102	0.139	2833.088	CPSF_A (PF03178, IPR004871): CPSF A subunit region MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term
72	DDB2	suppressor	26	0.507	214.226	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
73	DDIT4	interactor	3	1.000	0	RTP801_C (PF07809, IPR012918): RTP801 C-terminal region
74	DDX21	interactor	8	0.393	3.245	CRT10 (PF08728, IPR014839): CRT10 DEAD (PF00270, IPR011545): DEAD/DEAH box helicase GUCT (PF08152, IPR012562): GUCT (NUC152) domain Sulfatase (PF00884, IPR000917): Sulfatase MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal
75	DDX5	oncoprotein	30	0.520	40.523	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase P68HR (PF08061, IPR012587): P68HR (NUC004) repeat ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
76	DET1	interactor	9	0.750	1.743	Det1 (PF09737, IPR019138): De-etiolated protein 1 Det1
77	DHX15	interactor	26	0.483	41.941	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain AAA_29 (PF13555): P-loop containing region of AAA domain
78	DHX9	oncoprotein	30	0.464	157.288	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold T2SSE (PF00437, IPR001482): Type II/IV secretion system protein HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
79	DICER1	suppressor	8	0.619	1.284	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Dicer_dimer (PF03368, IPR005034): Dicer dimerisation domain PAZ (PF02170, IPR003100, SM00949): PAZ domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain Ribonuclease_3 (PF00636, IPR000999, SM00535): Ribonuclease III domain PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 (PF15387, IPR027893): Domain of unknown function (DUF4611)
80	DLC1	suppressor	5	1.000	0	RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) START (PF01852, IPR002913, SM00234): START domain DUF4561 (PF15120, IPR027818): Domain of unknown function (DUF4561)
81	DNAJC10	interactor	15	0.648	145.468	DnaJ (PF00226, IPR001623, SM00271): DnaJ domain Thioredoxin (PF00085, IPR013766): Thioredoxin Thioredoxin_6 (PF13848): Thioredoxin-like domain
82	DNMT3B	suppressor	9	0.556	4.713	DNA_methylase (PF00145, IPR001525): C-5 cytosine-specific DNA methylase PWWP (PF00855, IPR000313, SM00293): PWWP domain
83	DPPA4	interactor	10	0.444	8.198	Ribosomal_L40e (PF01020, IPR001975): Ribosomal L40e family DCR (PF14047, IPR025891): Dppa2/4 conserved region Dppa2_A (PF14049, IPR025892): Dppa2/4 conserved region in higher vertebrates
84	DTL	interactor	21	0.457	50.671	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
85	EED	suppressor	51	0.198	315.949	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
86	EEF1A1	suppressor	50	0.395	225.909	GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
87	EEF1A2	oncoprotein	16	0.725	2.790	GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
88	EMD	interactor	20	0.357	46.877	LEM (PF03020, IPR003887, SM00540): LEM domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
89	ENO1	oncoprotein	20	0.547	28.921	Enolase_C (PF00113, IPR020810): Enolase, C-terminal TIM barrel domain Enolase_N (PF03952, IPR020811): Enolase, N-terminal domain
90	ERCC6	oncoprotein	17	0.515	16.200	Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Spt5-NGN (PF03439, IPR005100): Early transcription elongation factor of RNA pol II, NGN section Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
91	ERCC8	oncoprotein	26	0.517	51.688	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain DUF4859 (PF16151, IPR032339): Domain of unknown function (DUF4859)
92	EWSR1	oncoprotein	45	0.353	242.684	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head
93	FBXO6	interactor	65	0.182	867.978	FBA (PF04300, IPR007397): F-box associated region F-box-like (PF12937, IPR001810): F-box-like
94	FBXW5	interactor	8	0.679	4.007	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat F-box-like (PF12937, IPR001810): F-box-like
95	FBXW8	interactor	10	0.867	0.617	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like
96	FUS	suppressor	48	0.419	170.059	Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others Limkain-b1 (PF11608, IPR024582): Limkain b1 FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head
97	GLB1L3	interactor	2	1.000	0	Glyco_hydro_35 (PF01301, IPR001944): Glycosyl hydrolases family 35 BetaGal_dom4_5 (PF13364, IPR025300): Beta-galactosidase jelly roll domain
98	GLMN	oncoprotein	6	0.867	0.491	Kinetochor_Ybp2 (PF08568, IPR013877): Uncharacterised protein family, YAP/Alf4/glomulin
99	GNB1	interactor	6	0.267	31.012	Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
100	GNB2	interactor	5	0.900	0.168	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat CALM_bind (PF16025): Calcium-dependent calmodulin binding WD40_like (PF17005, IPR031544): WD40-like domain
101	GNB3	interactor	1	0	0	Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
102	GNB4	interactor	4	0.500	1.968	Spore_YhcN_YlaJ (PF09580, IPR019076): Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
103	GNB5	interactor	5	0.500	0.963	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain WD40_like (PF17005, IPR031544): WD40-like domain
104	GPS1	interactor	30	0.533	75.440	RPN7 (PF10602, IPR019585): 26S proteasome subunit RPN7 PCI (PF01399, IPR000717, SM00088): PCI domain
105	GRK5	protein found in more fusions	24	0.257	73.242	Pkinase (PF00069, IPR000719): Protein kinase domain RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
106	GRWD1	interactor	16	0.617	12.672	Voldacs (PF03517): Regulator of volume decrease after cellular swelling WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
107	H2AFV	interactor	10	0.644	2.011	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
108	HAX1	interactor	10	0.511	4.672	Mlf1IP (PF10248, IPR019376): Myelodysplasia-myeloid leukemia factor 1-interacting protein
109	HIST1H1A	interactor	16	0.317	31.166	Mucin (PF01456, IPR000458): Mucin-like glycoprotein Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal
110	HIST1H1C	oncoprotein	21	0.505	28.751	Amelin (PF05111, IPR007798, SM00817): Ameloblastin precursor (Amelin) Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family DUF4349 (PF14257, IPR025645): Domain of unknown function (DUF4349)
111	HIST1H2AB	interactor	13	0.603	7.333	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
112	HIST1H2AE	interactor	8	0.786	0.164	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
113	HIST1H2AG	interactor	11	0.691	2.995	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
114	HIST1H2AI	interactor	8	0.786	0.164	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
115	HIST1H2AJ	interactor	8	0.786	0.164	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
116	HIST1H2AK	interactor	8	0.786	0.164	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
117	HIST1H2AL	interactor	8	0.786	0.164	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
118	HIST1H2AM	interactor	8	0.786	0.164	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
119	HIST1H2BG	oncoprotein	7	0.524	6.167	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
120	HIST1H3A	interactor	25	0.217	124.539	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
121	HNRNPA2B1	oncoprotein	29	0.579	35.890	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
122	HNRNPAB	interactor	19	0.719	6.737	CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain GRP (PF07172, IPR010800): Glycine rich protein family NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2462 (PF09495, IPR019034): Protein of unknown function (DUF2462)
123	HNRNPD	oncoprotein	35	0.512	87.175	CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Keratin_2_head (PF16208, IPR032444): Keratin type II head
124	HNRNPDL	interactor	27	0.641	31.171	CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
125	HNRNPF	interactor	30	0.616	35.614	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spot_14 (PF07084, IPR009786): Thyroid hormone-inducible hepatic protein Spot 14 zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger
126	HNRNPH1	oncoprotein	32	0.609	33.488	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger
127	HNRNPH3	protein found in more fusions	25	0.725	11.796	Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
128	HNRNPUL1	interactor	20	0.813	2.470	Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator Rox3 (PF08633, IPR013942): Rox3 mediator complex subunit SAP (PF02037, IPR003034, SM00513): SAP domain SPRY (PF00622, IPR003877, SM00449): SPRY domain AAA_33 (PF13671): AAA domain PRIMA1 (PF16101): Proline-rich membrane anchor 1
129	HOXA9	oncoprotein	3	1.000	0	Hox9_act (PF04617, IPR006711): Hox9 activation region Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
130	HOXB4	interactor	3	1.000	0	DUF4106 (PF13388, IPR025179): Protein of unknown function (DUF4106)
131	HSP90AA1	oncoprotein	63	0.309	549.572	HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein
132	HSP90AB1	oncoprotein	38	0.444	96.579	HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein
133	HSP90B1	suppressor	18	0.490	168.720	CobT (PF06213, IPR006538): Cobalamin biosynthesis protein CobT HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein Sigma70_ner (PF04546, IPR007631): Sigma-70, non-essential region
134	HSPA1A	interactor	30	0.616	27.820	HSP70 (PF00012, IPR013126): Hsp70 protein
135	HSPA1B	interactor	16	0.625	11.824	HSP70 (PF00012, IPR013126): Hsp70 protein
136	HSPA1L	interactor	19	0.643	80.622	HSP70 (PF00012, IPR013126): Hsp70 protein
137	HSPA5	oncoprotein	56	0.379	1406.222	HSP70 (PF00012, IPR013126): Hsp70 protein
138	HSPA7	interactor	13	0.667	2.292	NA
139	HSPA8	oncoprotein	47	0.405	204.767	HSP70 (PF00012, IPR013126): Hsp70 protein
140	HSPA9	oncoprotein	30	0.462	59.404	HSP70 (PF00012, IPR013126): Hsp70 protein
141	HSPD1	suppressor	31	0.447	94.955	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
142	IARS	interactor	12	0.515	9.966	Anticodon_1 (PF08264, IPR013155): Anticodon-binding domain of tRNA tRNA-synt_1 (PF00133, IPR002300): tRNA synthetases class I (I, L, M and V)
143	IFI16	suppressor	11	0.255	19.305	HIN (PF02760, IPR004021): HIN-200/IF120x domain PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain Mitofilin (PF09731, IPR019133): Mitochondrial inner membrane protein
144	IGF2BP1	oncoprotein	14	0.495	7.284	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_1 (PF00013, IPR004088, SM00322): KH domain KH_4 (PF13083): KH domain MOEP19 (PF16005, IPR031952): KH-like RNA-binding domain
145	IGHV3OR15-7	interactor	8	0.964	0.018	V-set (PF07686, IPR013106): Immunoglobulin V-set domain
146	IP6K1	interactor	5	0.900	0.133	IPK (PF03770, IPR005522): Inositol polyphosphate kinase SIN1 (PF05422, IPR008828): Stress-activated map kinase interacting protein 1 (SIN1)
147	KAT14	oncoprotein	4	1.000	0	Acetyltransf_10 (PF13673, IPR000182): Acetyltransferase (GNAT) domain
148	KAT2A	interactor	17	0.283	157.687	Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain NICE-1 (PF15845, IPR031698): Cysteine-rich C-terminal 1 family
149	KLHL9	interactor	6	1.000	0	BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
150	KRT1	interactor	17	0.713	6.345	Filament (PF00038, IPR001664): Intermediate filament protein Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region Keratin_2_head (PF16208, IPR032444): Keratin type II head Keratin_2_tail (PF16210, IPR032449): Keratin type II cytoskeletal 1 tail
151	KRT10	interactor	13	0.846	1.082	Filament (PF00038, IPR001664): Intermediate filament protein FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
152	KRT2	interactor	18	0.582	13.767	Filament (PF00038, IPR001664): Intermediate filament protein Keratin_2_head (PF16208, IPR032444): Keratin type II head
153	KRT24	interactor	9	0.972	0.018	Filament (PF00038, IPR001664): Intermediate filament protein DUF4766 (PF15973, IPR031903): Domain of unknown function (DUF4766)
154	KRT75	interactor	10	0.933	0.072	Filament (PF00038, IPR001664): Intermediate filament protein Keratin_2_head (PF16208, IPR032444): Keratin type II head
155	KRT76	interactor	7	0.905	0.054	Filament (PF00038, IPR001664): Intermediate filament protein Keratin_2_head (PF16208, IPR032444): Keratin type II head
156	KRT9	interactor	12	0.818	1.082	Filament (PF00038, IPR001664): Intermediate filament protein FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
157	LGALS3BP	oncoprotein	25	0.670	25.281	BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch SRCR (PF00530, IPR001190): Scavenger receptor cysteine-rich domain SRCR_2 (PF15494, IPR017448): Scavenger receptor cysteine-rich domain
158	LOC285556	interactor	1	0	0	Apt1 (PF10351, IPR019443): Golgi-body localisation protein domain DUF4585 (PF15232, IPR027838): Domain of unknown function (DUF4585)
159	LRWD1	interactor	3	0.667	0.200	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat
160	MAP4	oncoprotein	8	0.429	7.190	SdiA-regulated (PF06977, IPR009722): SdiA-regulated Tubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeat DUF3275 (PF11679, IPR021693): Protein of unknown function (DUF3275)
161	MCM10	interactor	8	0.464	44.114	Mcm10 (PF09332, IPR015411): Mcm10 replication factor zf-primase (PF09329, IPR015408): Primase zinc finger AATF-Che1 (PF13339, IPR025160): Apoptosis antagonizing transcription factor
162	MCM2	oncoprotein	92	0.158	1270.699	AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain
163	MDM2	oncoprotein	48	0.286	290.480	Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region Presenilin (PF01080, IPR001108): Presenilin SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
164	MRPS11	interactor	7	0.619	4.256	Ribosomal_S11 (PF00411, IPR001971): Ribosomal protein S11
165	MTM1	interactor	1	0	0	GRAM (PF02893, IPR004182, SM00568): GRAM domain Myotub-related (PF06602, IPR010569): Myotubularin-like phosphatase domain 3-PAP (PF12578, IPR022587): Myotubularin-associated protein
166	MYB	oncoprotein	10	0.356	54.073	Cmyb_C (PF09316, IPR015395): C-myb, C-terminal LMSTEN (PF07988, IPR012642): LMSTEN motif Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
167	MYC	oncoprotein	36	0.222	178.096	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region
168	NACC1	interactor	3	1.000	0	BTB (PF00651, IPR013069, SM00225): BTB/POZ domain BEN (PF10523, IPR018379, SM01025): BEN domain
169	NANOG	interactor	19	0.183	46.846	Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
170	NCL	protein found in more fusions	37	0.446	88.702	DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Myc_N (PF01056, IPR012682): Myc amino-terminal region RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YL1 (PF05764, IPR008895): YL1 nuclear protein Limkain-b1 (PF11608, IPR024582): Limkain b1
171	NEDD8	interactor	99	0.213	981.603	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
172	NF2	suppressor	22	0.195	59.206	ERM (PF00769, IPR011259): Ezrin/radixin/moesin family FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain
173	NFKB1	suppressor	16	0.600	9.659	Death (PF00531, IPR000488, SM00005): Death domain GHMP_kinases_C (PF08544, IPR013750): GHMP kinases C terminal RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
174	NPM1	suppressor	60	0.365	351.687	Nucleoplasmin (PF03066): Nucleoplasmin/nucleophosmin domain SDA1 (PF05285, IPR007949): SDA1 NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain
175	NUP43	interactor	4	0.667	0.848	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
176	NXPH3	interactor	2	1.000	0	Neurexophilin (PF06312, IPR026845): Neurexophilin
177	OTULIN	interactor	3	1.000	0	Peptidase_C101 (PF16218, IPR023235): Peptidase family C101
178	PABPC1	oncoprotein	29	0.601	47.069	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain YflT (PF11181, IPR025889): Heat induced stress protein YflT
179	PABPC4	interactor	19	0.602	198.391	ApbA_C (PF08546, IPR013752): Ketopantoate reductase PanE/ApbA C terminal RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain HHV-5_US34A (PF17087, IPR031384): Herpesvirus US34A protein family
180	PCBD1	protein found in more fusions	10	0.778	1.356	Pterin_4a (PF01329, IPR001533): Pterin 4 alpha carbinolamine dehydratase
181	PCNA	oncoprotein	27	0.382	165.222	PCNA_C (PF02747, IPR022649): Proliferating cell nuclear antigen, C-terminal domain PCNA_N (PF00705, IPR022648): Proliferating cell nuclear antigen, N-terminal domain
182	PFDN4	interactor	5	0	20.282	Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit
183	PHIP	oncoprotein	9	0.528	7.101	DTHCT (PF08070, IPR012542): DTHCT (NUC029) region DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) E7 (PF00527, IPR000148): E7 protein, Early protein WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
184	POC1B	interactor	4	0.500	80.577	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
185	PON2	interactor	4	0.667	11.910	Arylesterase (PF01731, IPR002640): Arylesterase
186	POU5F1	oncoprotein	29	0.172	107.471	Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
187	PPP2R1A	oncoprotein	19	0.462	25.187	TAF6_C (PF07571, IPR011442): TAF6 C-terminal HEAT repeat domain HEAT (PF02985, IPR000357): HEAT repeat HEAT_PBS (PF03130, IPR004155, SM00567): PBS lyase HEAT-like repeat HEAT_2 (PF13646): HEAT repeats
188	PRDX1	oncoprotein	17	0.567	7.950	AhpC-TSA (PF00578, IPR000866): AhpC/TSA family 1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin
189	PRMT5	protein found in more fusions	18	0.353	38.155	PRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase
190	PSMC6	interactor	12	0.327	39.631	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) AAA_2 (PF07724, IPR013093): AAA domain (Cdc48 subfamily) TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Prot_ATP_ID_OB (PF16450, IPR032501): Proteasomal ATPase OB/ID domain
191	PSMD8	interactor	8	0.179	42.946	CSN8_PSD8_EIF3K (PF10075): CSN8/PSMD8/EIF3K family
192	PTGS2	oncoprotein	11	0.689	2.261	An_peroxidase (PF03098, IPR002007): Animal haem peroxidase EGF (PF00008, IPR000742, SM00181): EGF-like domain
193	PWP1	interactor	13	0.667	9.395	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
194	PYGO2	interactor	9	0.607	4.904	PHD (PF00628, IPR019787, SM00249): PHD-finger
195	QPCT	interactor	9	0.944	0.043	Peptidase_M28 (PF04389, IPR007484): Peptidase family M28
196	RAD21	oncoprotein	24	0.413	32.462	Rad21_Rec8 (PF04824, IPR006909): Conserved region of Rad21 / Rec8 like protein Rad21_Rec8_N (PF04825, IPR006910): N terminus of Rad21 / Rec8 like protein FAM176 (PF14851): FAM176 family WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
197	RAG1	interactor	8	0.619	1.731	zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) zf-RAG1 (PF10426, IPR019485): Recombination-activating protein 1 zinc-finger domain RAG1_imp_bd (PF12560): RAG1 importin binding RAG1 (PF12940, IPR024627): Recombination-activation protein 1 (RAG1), recombinase
198	RASSF1	suppressor	10	0.667	2.282	RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) Nore1-SARAH (PF16517, IPR011524): Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain
199	RBBP4	oncoprotein	16	0.408	31.210	eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
200	RBBP5	oncoprotein	11	0.533	9.297	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457) ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
201	RBBP7	suppressor	12	0.470	17.782	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
202	RBX1	oncoprotein	56	0.265	692.845	zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain
203	RFWD2	suppressor	28	0.587	35.820	Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein IncA (PF04156, IPR007285): IncA protein WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) WD40_like (PF17005, IPR031544): WD40-like domain
204	RGS12	interactor	2	1.000	0	PT-HINT (PF07591): Pretoxin HINT domain GoLoco (PF02188, IPR003109, SM00390): GoLoco motif PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) RBD (PF02196, IPR003116, SM00455): Raf-like Ras-binding domain RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain RGS12_us2 (PF16611): Unstructured region between RBD and GoLoco RGS12_usC (PF16612): C-terminal unstructured region of RGS12 RGS12_us1 (PF16613): Unstructured region of RGS12
205	RNF7	oncoprotein	15	0.495	18.090	zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain Prok-RING_1 (PF14446): Prokaryotic RING finger family 1
206	RPL10A	interactor	35	0.649	39.836	Ribosomal_L1 (PF00687, IPR028364): Ribosomal protein L1p/L10e family
207	RPL11	suppressor	38	0.654	39.151	Ribosomal_L5 (PF00281, IPR002132): Ribosomal protein L5 Ribosomal_L5_C (PF00673, IPR002132): ribosomal L5P family C-terminus
208	RPL15	interactor	37	0.676	39.526	Ribosomal_L15e (PF00827, IPR000439): Ribosomal L15
209	RPL19	interactor	30	0.754	20.606	DUF1682 (PF07946, IPR012879): Protein of unknown function (DUF1682) Ribosomal_L19e (PF01280, IPR000196): Ribosomal protein L19e
210	RPL22	oncoprotein	32	0.633	42.636	Ribosomal_L22e (PF01776, IPR002671): Ribosomal L22e protein family
211	RPL23A	interactor	35	0.699	25.197	Ribosomal_L23 (PF00276, IPR013025): Ribosomal protein L23 Ribosomal_L23eN (PF03939, IPR005633): Ribosomal protein L23, N-terminal domain
212	RPL26	oncoprotein	16	0.792	3.064	TP2 (PF01254, IPR000678): Nuclear transition protein 2 Ribosomal_L26 (PF16906, IPR005756): Ribosomal proteins L26 eukaryotic, L24P archaeal
213	RPL38	interactor	30	0.697	39.527	Ribosomal_L38e (PF01781, IPR002675): Ribosomal L38e protein family
214	RPL4	interactor	42	0.567	105.212	Ribosomal_L4 (PF00573, IPR002136): Ribosomal protein L4/L1 family Ribos_L4_asso_C (PF14374, IPR025755): 60S ribosomal protein L4 C-terminal domain
215	RPL7A	interactor	31	0.630	28.652	Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
216	RPL7AP27	interactor	10	0.800	0.552	NA
217	RPLP1	interactor	29	0.831	10.329	Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
218	RPLP2	protein found in more fusions	36	0.667	31.529	Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
219	RPS14	interactor	36	0.649	45.274	Ribosomal_S11 (PF00411, IPR001971): Ribosomal protein S11
220	RPS15A	interactor	36	0.622	56.137	Ribosomal_S8 (PF00410, IPR000630): Ribosomal protein S8
221	RPS18	protein found in more fusions	30	0.717	28.678	Ribosomal_S13 (PF00416, IPR001892): Ribosomal protein S13/S18
222	RPS2	interactor	39	0.575	85.095	Ribosomal_S5 (PF00333, IPR013810): Ribosomal protein S5, N-terminal domain Ribosomal_S5_C (PF03719, IPR005324): Ribosomal protein S5, C-terminal domain
223	RPS20	interactor	34	0.684	39.745	Ribosomal_S10 (PF00338, IPR027486): Ribosomal protein S10p/S20e
224	RPS3	interactor	42	0.541	101.666	KH_2 (PF07650, IPR004044): KH domain Ribosomal_S3_C (PF00189, IPR001351): Ribosomal protein S3, C-terminal domain
225	RPTOR	protein found in more fusions	6	0.700	2.667	HEAT (PF02985, IPR000357): HEAT repeat WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain HEAT_2 (PF13646): HEAT repeats Raptor_N (PF14538, IPR029347): Raptor N-terminal CASPase like domain
226	SALL2	suppressor	7	0.619	2.549	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type MPP6 (PF10175, IPR019324): M-phase phosphoprotein 6 zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding Astro_capsid_p (PF12226, IPR022027): Turkey astrovirus capsid protein zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
227	SAMHD1	protein found in more fusions	12	0.636	4.448	HD (PF01966, IPR006674): HD domain SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
228	SAP130	interactor	10	0.511	6.447	SAP130_C (PF16014, IPR031963): Histone deacetylase complex subunit SAP130 C-terminus
229	SCAF11	interactor	8	0.393	7.958	DUF566 (PF04484, IPR007573): Family of unknown function (DUF566) Phage_XkdX (PF09693, IPR010022): Phage uncharacterised protein (Phage_XkdX) zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
230	SDHA	suppressor	12	0.864	1.311	FAD_binding_2 (PF00890, IPR003953): FAD binding domain Succ_DH_flav_C (PF02910, IPR015939): Fumarate reductase flavoprotein C-term
231	SENP8	interactor	6	0.800	0.517	Peptidase_C48 (PF02902, IPR003653): Ulp1 protease family, C-terminal catalytic domain
232	SF3B3	interactor	21	0.500	29.405	CPSF_A (PF03178, IPR004871): CPSF A subunit region MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term
233	SFXN1	interactor	3	0.333	21.523	Mtc (PF03820, IPR004686): Tricarboxylate carrier
234	SH3RF2	interactor	2	1.000	0	SH3_2 (PF07653, IPR011511): Variant SH3 domain TUDOR (PF00567, IPR002999, SM00333): Tudor domain UPF0547 (PF10571, IPR018886): Uncharacterised protein family UPF0547 SH3_1 (PF00018, IPR001452, SM00326): SH3 domain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger SH3_9 (PF14604, IPR001452): Variant SH3 domain
235	SKP1	oncoprotein	37	0.353	147.611	Skp1 (PF01466, IPR016072, SM00512): Skp1 family, dimerisation domain Skp1_POZ (PF03931, IPR016073): Skp1 family, tetramerisation domain
236	SKP2	suppressor	22	0.468	46.697	LRR_1 (PF00560, IPR001611): Leucine Rich Repeat LRR_2 (PF07723, IPR013101): Leucine Rich Repeat LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) F-box-like (PF12937, IPR001810): F-box-like LRR_6 (PF13516, IPR001611): Leucine Rich repeat LRR_8 (PF13855, IPR001611): Leucine rich repeat
237	SLA	interactor	1	0	0	SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
238	SLC25A22	interactor	5	0.400	4.532	Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein DUF4257 (PF14074, IPR025353): Protein of unknown function (DUF4257)
239	SLC25A5	interactor	29	0.650	21.718	Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
240	SLC25A6	interactor	12	0.439	15.060	Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
241	SMAD9	interactor	7	0.200	23.125	MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain
242	SNRNP40	interactor	5	0.800	0.536	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
243	SNRNP70	interactor	23	0.518	288.891	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
244	SNRPA	interactor	15	0.714	3.405	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
245	SNRPB	interactor	13	0.756	5.846	LSM (PF01423, IPR001163): LSM domain
246	SNRPD1	interactor	28	0.524	54.648	API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5) LSM (PF01423, IPR001163): LSM domain
247	SNRPD3	interactor	19	0.573	20.503	LSM (PF01423, IPR001163): LSM domain
248	SNRPE	interactor	16	0.717	11.948	LSM (PF01423, IPR001163): LSM domain
249	SRSF3	oncoprotein	19	0.561	25.019	DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
250	SSBP1	interactor	22	0.538	28.694	SSB (PF00436, IPR000424): Single-strand binding protein family
251	SUGT1	interactor	9	0.500	8.244	CheC (PF04509, IPR007597): CheC-like family CS (PF04969, IPR007052): CS domain SGS (PF05002, IPR007699): SGS domain TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat
252	SYNM	suppressor	2	1.000	0	Filament (PF00038, IPR001664): Intermediate filament protein CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167
253	TAF15	oncoprotein	16	0.625	5.959	API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5) GRP (PF07172, IPR010800): Glycine rich protein family Presenilin (PF01080, IPR001108): Presenilin RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
254	TCHP	suppressor	2	1.000	0	TAF8_C (PF10406, IPR019473): Transcription factor TFIID complex subunit 8 C-term TPH (PF13868): Trichohyalin-plectin-homology domain PNRC (PF15365, IPR028322): Proline-rich nuclear receptor coactivator
255	TCTN1	interactor	4	0.500	3.331	DUF1619 (PF07773, IPR011677): Protein of unknown function (DUF1619)
256	TFG	oncoprotein	21	0.595	22.302	ARS2 (PF04959, IPR007042): Arsenite-resistance protein 2 MucBP (PF06458, IPR009459): MucBP domain PB1 (PF00564, IPR000270, SM00666): PB1 domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
257	TIA1	interactor	12	0.591	8.847	Calcipressin (PF04847, IPR006931): Calcipressin RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt (PF14703, IPR027815): Cytosolic domain of 10TM putative phosphate transporter
258	TIAL1	interactor	13	0.654	4.244	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
259	TLE2	protein found in more fusions	3	1.000	0	TLE_N (PF03920, IPR005617): Groucho/TLE N-terminal Q-rich domain WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain WD40_like (PF17005, IPR031544): WD40-like domain
260	TOR1AIP2	interactor	11	0.800	2.250	LAP1C (PF05609, IPR008662): Lamina-associated polypeptide 1C (LAP1C)
261	TP53	suppressor	85	0.184	1221.884	DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
262	TRPC4AP	interactor	7	0.810	0.857	Put_DNA-bind_N (PF06971, IPR009718): Putative DNA-binding protein N-terminus DUF3689 (PF12463, IPR022162): Protein of unknown function (DUF3689)
263	TUBA1B	protein found in more fusions	10	0.400	6.815	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
264	TUBA1C	protein found in more fusions	34	0.469	73.642	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
265	TUBA4A	interactor	22	0.649	32.183	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
266	TUBA4B	interactor	10	0.822	1.080	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
267	TUBB	protein found in more fusions	38	0.457	112.018	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
268	TUBB1	interactor	11	0.655	3.155	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
269	TUBB4B	interactor	27	0.536	32.703	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
270	TUBG1	protein found in more fusions	44	0.249	361.881	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
271	UBC	protein found in more fusions	66	0.258	980.393	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
272	UBE2E3	protein found in more fusions	11	0.689	3.373	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
273	UBQLN1	protein found in more fusions	10	0.083	56.604	Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family Fur_reg_FbpB (PF13040, IPR025004): Fur-regulated basic protein B FAM199X (PF15814, IPR029672): Protein family FAM199X
274	UBXN7	interactor	15	0.562	17.667	UBX (PF00789, IPR001012, SM00166): UBX domain UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif Thioredoxin_7 (PF13899): Thioredoxin-like UBA_4 (PF14555): UBA-like domain
275	UNK	interactor	24	0.254	96.925	MbeD_MobD (PF04899, IPR006983): MbeD/MobD like NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) zf-CCCH_2 (PF14608): RNA-binding, Nab2-type zinc finger Torus (PF16131, IPR032297): Torus domain
276	USP7	oncoprotein	26	0.380	73.441	MATH (PF00917, IPR002083, SM00061): MATH domain UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg (PF12436, IPR024729): ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 (PF14533, IPR029346): Ubiquitin-specific protease C-terminal
277	VCP	protein found in more fusions	57	0.259	562.279	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2 CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain TniB (PF05621, IPR008868): Bacterial TniB protein Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
278	WDR26	interactor	8	0.464	7.123	eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
279	WDR5	interactor	26	0.274	134.753	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
280	WDR5B	interactor	3	1.000	0	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
281	WDR61	interactor	8	0.571	4.766	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
282	WDR76	interactor	11	0.418	13.661	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat SPATIAL (PF15256): SPATIAL
283	WDR82	oncoprotein	9	0.583	5.324	MinC_C (PF03775, IPR005526): Septum formation inhibitor MinC, C-terminal domain WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Frtz (PF11768, IPR024511): WD repeat-containing and planar cell polarity effector protein Fritz ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
284	WDTC1	interactor	6	0.667	2.664	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat
285	WSB1	interactor	4	1.000	0	PD40 (PF07676, IPR011659): WD40-like Beta Propeller Repeat WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain SOCS_box (PF07525, IPR001496): SOCS box
286	WSB2	interactor	4	0.833	0.074	PD40 (PF07676, IPR011659): WD40-like Beta Propeller Repeat WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 SOCS_box (PF07525, IPR001496): SOCS box
287	XXYLT1	oncoprotein	1	0	0	Glyco_transf_8 (PF01501, IPR002495): Glycosyl transferase family 8
288	ZNF407	interactor	2	1.000	0	AKAP95 (PF04988, IPR007071): A-kinase anchoring protein 95 (AKAP95) zf-BED (PF02892, IPR003656, SM00614): BED zinc finger zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies) zf-met (PF12874): Zinc-finger of C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zinc_ribbon_4 (PF13717): zinc-ribbon domain zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain
289	ZNF525	interactor	2	1.000	0	KRAB (PF01352, IPR001909, SM00349): KRAB box zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger

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