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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)133
The number (and %) of the onco-proteins32 (24.06 %)
The number (and %) of the tumor suppressors15 (11.28 %)
Total number of binary PPIs (saturation %)2918 (33.24 %)
The number (and %) of affected PPIs133 (4.56 %)
The number of possible different fusions27
PPI diameter4
PPI radius2
The average degree of PPI43.353
Assortativity coefficient0.3253
The network average Clustering coefficient0.731
The number (and %) of a zero Clustering coefficients5 (3.76 %)
The number (and %) of a zero Betweenness Centrality14 (10.53 %)


List of the fusions

PPI for parental proteins: RPS21,MITF All fusions
Proteins found in more fusions NPM1 (see 1 fusions); CUL1 (see 3 fusions); PAX6 (see 1 fusions); PIAS1 (see 3 fusions); MARK3 (see 1 fusions); EP300 (see 1 fusions); HNRNPU/RPL24 (see 1 fusions); RPLP2 (see 1 fusions); APP (see 5 fusions); APP/RPL34 (see 1 fusions); RPS24/RPS23 (see 1 fusions); RPL27/RPS6 (see 1 fusions); HINT1 (see 3 fusions); EPAS1 (see 1 fusions); CUL3 (see 1 fusions); RPLP0/RPLP0P6 (see 10 fusions); PIAS2 (see 2 fusions); RPL37A/RPS24 (see 1 fusions); COPS5 (see 1 fusions); RACK1/FN1 (see 1 fusions); SFN (see 1 fusions); RPL5 (see 1 fusions); PABPC1 (see 3 fusions); RACK1 (see 3 fusions); FOS (see 4 fusions); FN1/RPL6 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Domains (Pfam, InterPro, SMART): description
1 RPS21parental protein1080.4553002.510Ribosomal_S21e (PF01249, IPR001931): Ribosomal protein S21e
2 MITFparental protein250.1201585.906HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
DUF3371 (PF11851, IPR021802): Domain of unknown function (DUF3371)
DUF4355 (PF14265, IPR025580): Domain of unknown function (DUF4355)
Di19_C (PF14571, IPR027935): Stress-induced protein Di19, C-terminal
MITF_TFEB_C_3_N (PF15951, IPR031867): MITF/TFEB/TFEC/TFE3 N-terminus
3 ABL1oncoprotein80.23852.393Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
FRG2 (PF15315, IPR026245): Facioscapulohumeral muscular dystrophy candidate 2
4 ADRM1interactor150.81915.737Proteasom_Rpn13 (PF04683, IPR006773): Proteasome complex subunit Rpn13 ubiquitin receptor
GET2 (PF08690, IPR028143): GET complex subunit GET2
RPN13_C (PF16550, IPR032368): UCH-binding domain
5 ANXA11interactor21.0000Annexin (PF00191, IPR018502, SM00335): Annexin
6 APPprotein found in more fusions340.455712.086APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
7 ATP5Iinteractor50.60028.950ATP-synt_E (PF05680, IPR008386): ATP synthase E chain
8 CAND1interactor700.81584.883Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981)
HEAT (PF02985, IPR000357): HEAT repeat
TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20)
RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
9 CCDC68interactor21.0000bZIP_1 (PF00170, IPR004827): bZIP transcription factor
Med9 (PF07544, IPR011425): RNA polymerase II transcription mediator complex subunit 9
Spore_YhcN_YlaJ (PF09580, IPR019076): Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
10 CDK2suppressor610.623796.103Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
11 CLCA2interactor100CLCA (PF08434, IPR013642): Calcium-activated chloride channel
12 CLNS1Ainteractor50.8000.153Voldacs (PF03517): Regulator of volume decrease after cellular swelling
13 COPS5protein found in more fusions660.82756.927JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
14 CUL1suppressor670.81468.376Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
15 CUL3protein found in more fusions710.704248.984Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
16 DYNLL1interactor90.8930.153Dynein_light (PF01221, IPR001372): Dynein light chain type 1
17 EBPinteractor30.6670.400Phage_holin_3_6 (PF07332, IPR009937): Putative Actinobacterial Holin-X, holin superfamily III
EBP (PF05241, IPR007905): Emopamil binding protein
18 ELAVL1oncoprotein180.360237.589RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
19 EP300oncoprotein130.303336.298Creb_binding (PF09030, IPR014744): Creb binding
DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902)
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
KIX (PF02172, IPR003101): KIX domain
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger
HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
20 EPAS1suppressor80.42923.634Corona_I (PF03187, IPR004876): Corona nucleocapsid I protein
HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
PAS (PF00989, IPR013767, SM00091): PAS fold
HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1
PAS_11 (PF14598): PAS domain
21 FN1oncoprotein660.739187.425fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
22 FOSoncoprotein80.28685.736bZIP_1 (PF00170, IPR004827): bZIP transcription factor
23 HINT1suppressor31.0000HIT (PF01230, IPR001310): HIT domain
24 HIST1H3Einteractor210.7952.419Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
25 HK3interactor100Hexokinase_1 (PF00349, IPR022672): Hexokinase
Hexokinase_2 (PF03727, IPR022673): Hexokinase
26 HNRNPA1interactor280.624227.380RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
27 HNRNPMinteractor540.743185.947RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNP_M (PF11532, IPR024666): Heterogeneous nuclear ribonucleoprotein M
Collagen_mid (PF15984, IPR031929): Bacterial collagen, middle region
28 HNRNPUprotein found in more fusions710.769221.302CDC45 (PF02724, IPR003874): CDC45-like protein
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SAP (PF02037, IPR003034, SM00513): SAP domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
AAA_33 (PF13671): AAA domain
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
29 ITGA4interactor570.738100.713FG-GAP (PF01839, IPR013517): FG-GAP repeat
Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region
Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
30 LEF1oncoprotein30.6673.910CTNNB1_binding (PF08347, IPR013558): N-terminal CTNNB1 binding
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
31 MARK3protein found in more fusions3012.134KA1 (PF02149, IPR001772): Kinase associated domain 1
Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
Pkinase (PF00069, IPR000719): Protein kinase domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
32 MAST3interactor21.0000DUF1908 (PF08926, IPR015022): Domain of unknown function (DUF1908)
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Pkinase (PF00069, IPR000719): Protein kinase domain
ACTL7A_N (PF16840, IPR031769): Actin-like protein 7A N-terminus
33 MRPS21interactor51.0000Ribosomal_S21 (PF01165, IPR001911): Ribosomal protein S21
34 MTHFD1interactor60.8000.127FTHFS (PF01268, IPR000559): Formate--tetrahydrofolate ligase
THF_DHG_CYH (PF00763, IPR020630): Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
THF_DHG_CYH_C (PF02882, IPR020631): Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
35 NACA2interactor50.9000.041NAC (PF01849, IPR002715): NAC domain
36 NPM1suppressor700.757269.773Nucleoplasmin (PF03066): Nucleoplasmin/nucleophosmin domain
SDA1 (PF05285, IPR007949): SDA1
NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain
37 NUDCD2interactor30.33311.302CS (PF04969, IPR007052): CS domain
DUF3110 (PF11360, IPR021503): Protein of unknown function (DUF3110)
38 PABPC1oncoprotein450.681146.143RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain
YflT (PF11181, IPR025889): Heat induced stress protein YflT
39 PATZ1oncoprotein200AT_hook (PF02178, IPR017956, SM00384): AT hook motif
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
zf-C2H2_assoc3 (PF16637): Putative zinc-finger between two C2H2 zinc-fingers on Patz
40 PAX6suppressor40.6670.500PAX (PF00292, IPR001523, SM00351): 'Paired box' domain
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
41 PIAS1suppressor51.0000Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein
zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger
PINIT (PF14324, IPR023321): PINIT domain
UPF0544 (PF15749, IPR032739): Uncharacterised protein family UPF0544
42 PIAS2protein found in more fusions51.0000SAP (PF02037, IPR003034, SM00513): SAP domain
zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger
PINIT (PF14324, IPR023321): PINIT domain
43 PIAS3oncoprotein60.40016.199SAP (PF02037, IPR003034, SM00513): SAP domain
zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger
PINIT (PF14324, IPR023321): PINIT domain
44 PSMC1interactor200.574116.418AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
DivIC (PF04977, IPR007060): Septum formation initiator
DUF815 (PF05673, IPR008533): Protein of unknown function (DUF815)
Prot_ATP_ID_OB (PF16450, IPR032501): Proteasomal ATPase OB/ID domain
45 PSMC2interactor170.67538.287AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
46 PSMC6interactor190.70630.207AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
AAA_2 (PF07724, IPR013093): AAA domain (Cdc48 subfamily)
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
Prot_ATP_ID_OB (PF16450, IPR032501): Proteasomal ATPase OB/ID domain
47 PSMD1interactor210.552112.985PA26 (PF04636, IPR006730): PA26 p53-induced protein (sestrin)
PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat
HEAT_2 (PF13646): HEAT repeats
48 PSMD11interactor180.65434.501DUF247 (PF03140, IPR004158): Plant protein of unknown function
PCI (PF01399, IPR000717, SM00088): PCI domain
AAA_16 (PF13191): AAA ATPase domain
TPR_12 (PF13424): Tetratricopeptide repeat
49 PSMD13interactor150.81915.026Mitovir_RNA_pol (PF05919, IPR008686): Mitovirus RNA-dependent RNA polymerase
PCI (PF01399, IPR000717, SM00088): PCI domain
50 PSMD14interactor150.638140.303JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function
51 PSMD2oncoprotein210.500112.145PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat
THAP (PF05485, IPR006612, SM00980): THAP domain
HEAT_2 (PF13646): HEAT repeats
52 PSMD3interactor190.64942.387Rpn3_C (PF08375, IPR013586): Proteasome regulatory subunit C-terminal
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
PCI (PF01399, IPR000717, SM00088): PCI domain
Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat
TSKS (PF15358, IPR028214): Testis-specific serine kinase substrate
53 PSMD8interactor150.81016.789CSN8_PSD8_EIF3K (PF10075): CSN8/PSMD8/EIF3K family
54 RACK1suppressor440.76942.454WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
55 RAD21oncoprotein350.72350.116Rad21_Rec8 (PF04824, IPR006909): Conserved region of Rad21 / Rec8 like protein
Rad21_Rec8_N (PF04825, IPR006910): N terminus of Rad21 / Rec8 like protein
FAM176 (PF14851): FAM176 family
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
56 RAD23Bsuppressor130.61541.815K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
XPC-binding (PF09280, IPR015360): XPC-binding domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
DUF3123 (PF11321, IPR021470): Protein of unknown function (DUF3123)
57 RPL10suppressor700.85226.971Ribosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e
58 RPL10Ainteractor720.87322.704Ribosomal_L1 (PF00687, IPR028364): Ribosomal protein L1p/L10e family
59 RPL10Linteractor540.9622.507Ribosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e
Cytochrome_P460 (PF16694, IPR032033): Cytochrome P460
60 RPL11suppressor720.86230.014Ribosomal_L5 (PF00281, IPR002132): Ribosomal protein L5
Ribosomal_L5_C (PF00673, IPR002132): ribosomal L5P family C-terminus
61 RPL12interactor710.87625.304Ribosomal_L11 (PF00298, IPR020783): Ribosomal protein L11, RNA binding domain
Ribosomal_L11_N (PF03946, IPR020784): Ribosomal protein L11, N-terminal domain
62 RPL13interactor700.84926.665Ribosomal_L13e (PF01294, IPR001380): Ribosomal protein L13e
63 RPL14interactor720.86520.669KOW (PF00467, IPR005824, SM00739): KOW motif
Ribosomal_L14e (PF01929, IPR002784): Ribosomal protein L14
UPF0688 (PF15772, IPR031530): UPF0688 family
64 RPL15interactor680.90310.684Ribosomal_L15e (PF00827, IPR000439): Ribosomal L15
65 RPL17interactor630.85524.032Ribosomal_L22 (PF00237, IPR001063): Ribosomal protein L22p/L17e
66 RPL18interactor740.85630.643Ribosomal_L18 (PF17135): Ribosomal protein 60S L18 and 50S L18e
67 RPL18Ainteractor640.90717.769Ribosomal_L18A (PF01775, IPR023573): Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A
68 RPL19interactor710.86820.956DUF1682 (PF07946, IPR012879): Protein of unknown function (DUF1682)
Ribosomal_L19e (PF01280, IPR000196): Ribosomal protein L19e
69 RPL21interactor710.88320.545Ribosomal_L21e (PF01157, IPR001147): Ribosomal protein L21e
70 RPL22oncoprotein690.89312.708Ribosomal_L22e (PF01776, IPR002671): Ribosomal L22e protein family
71 RPL23interactor730.84161.239Ribosomal_L14 (PF00238, IPR000218): Ribosomal protein L14p/L23e
72 RPL23Ainteractor740.84238.743Ribosomal_L23 (PF00276, IPR013025): Ribosomal protein L23
Ribosomal_L23eN (PF03939, IPR005633): Ribosomal protein L23, N-terminal domain
73 RPL24protein found in more fusions720.84243.394MAS20 (PF02064, IPR002056): MAS20 protein import receptor
Ribosomal_L24e (PF01246, IPR000988): Ribosomal protein L24e
74 RPL27protein found in more fusions680.865102.360Ribosomal_L27e (PF01777, IPR001141): Ribosomal L27e protein family
75 RPL30interactor680.87625.366NCBP3 (PF10309, IPR019416): Nuclear cap-binding protein subunit 3
76 RPL31interactor680.87428.571Ribosomal_L31e (PF01198, IPR000054): Ribosomal protein L31e
77 RPL34protein found in more fusions480.89617.744Redoxin (PF08534, IPR013740): Redoxin
Ribosomal_L34e (PF01199, IPR008195): Ribosomal protein L34e
78 RPL37Aprotein found in more fusions690.86630.067Ribosomal_L37ae (PF01780, IPR002674): Ribosomal L37ae protein family
79 RPL4interactor740.84336.527Ribosomal_L4 (PF00573, IPR002136): Ribosomal protein L4/L1 family
Ribos_L4_asso_C (PF14374, IPR025755): 60S ribosomal protein L4 C-terminal domain
80 RPL5suppressor750.85327.867Ribosomal_L18_c (PF14204, IPR025607): Ribosomal L18 C-terminal region
Ribosomal_L5e (PF17144): Ribosomal large subunit proteins 60S L5, and 50S L18
81 RPL6protein found in more fusions730.84666.972Ribosomal_L6e (PF01159, IPR000915): Ribosomal protein L6e
Ribosomal_L6e_N (PF03868, IPR005568): Ribosomal protein L6, N-terminal domain
82 RPL7interactor730.826124.729Ribosomal_L30 (PF00327, IPR016082): Ribosomal protein L30p/L7e
Ribosomal_L30_N (PF08079, IPR012988): Ribosomal L30 N-terminal domain
83 RPL7Ainteractor710.84235.110Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
84 RPL9interactor700.89412.075Ribosomal_L6 (PF00347, IPR020040): Ribosomal protein L6
85 RPLP0protein found in more fusions710.86839.502Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
Ribosomal_L10 (PF00466, IPR001790): Ribosomal protein L10
86 RPLP0P6protein found in more fusions560.9562.798NA
87 RPLP1interactor600.92840.280Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
88 RPLP2protein found in more fusions660.86252.126Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
89 RPS10interactor710.85341.349S10_plectin (PF03501, IPR005326): Plectin/S10 domain
90 RPS11interactor730.84942.986Ribosomal_S17 (PF00366, IPR000266): Ribosomal protein S17
Ribosomal_S17_N (PF16205, IPR032440): Ribosomal_S17 N-terminal
91 RPS12interactor700.786141.052Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
92 RPS13interactor770.785128.660Ribosomal_S13_N (PF08069, IPR012606): Ribosomal S13/S15 N-terminal domain
Ribosomal_S15 (PF00312, IPR000589): Ribosomal protein S15
93 RPS15Ainteractor790.747176.368Ribosomal_S8 (PF00410, IPR000630): Ribosomal protein S8
94 RPS16interactor780.798109.719Ribosomal_S9 (PF00380, IPR000754): Ribosomal protein S9/S16
95 RPS17interactor580.85821.741Ribosomal_S17e (PF00833, IPR001210): Ribosomal S17
96 RPS18interactor720.83150.490Ribosomal_S13 (PF00416, IPR001892): Ribosomal protein S13/S18
97 RPS19interactor730.84143.019Ribosomal_S19e (PF01090, IPR001266): Ribosomal protein S19e
98 RPS2interactor790.781124.040Ribosomal_S5 (PF00333, IPR013810): Ribosomal protein S5, N-terminal domain
Ribosomal_S5_C (PF03719, IPR005324): Ribosomal protein S5, C-terminal domain
99 RPS20interactor750.80060.116Ribosomal_S10 (PF00338, IPR027486): Ribosomal protein S10p/S20e
100 RPS23protein found in more fusions690.88520.758Ribosom_S12_S23 (PF00164, IPR006032): Ribosomal protein S12/S23
101 RPS24protein found in more fusions700.88813.525Fascin (PF06268, IPR022768): Fascin domain
Ribosomal_S24e (PF01282, IPR001976): Ribosomal protein S24e
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
102 RPS25interactor770.79894.390Ribosomal_S25 (PF03297, IPR004977): S25 ribosomal protein
103 RPS26interactor650.863109.430Ribosomal_S26e (PF01283, IPR000892): Ribosomal protein S26e
104 RPS27Linteractor460.9286.228E7 (PF00527, IPR000148): E7 protein, Early protein
Ribosomal_S27e (PF01667, IPR000592): Ribosomal protein S27
zf-C2HC5 (PF06221, IPR009349): Putative zinc finger motif, C2HC5-type
DUF3382 (PF11862, IPR021807): Domain of unknown function (DUF3382)
105 RPS28interactor650.78787.885Ribosomal_S28e (PF01200, IPR000289): Ribosomal protein S28e
106 RPS29interactor330.9730.513Ribosomal_S14 (PF00253, IPR001209): Ribosomal protein S14p/S29e
107 RPS3interactor790.770279.388KH_2 (PF07650, IPR004044): KH domain
Ribosomal_S3_C (PF00189, IPR001351): Ribosomal protein S3, C-terminal domain
108 RPS3Ainteractor780.795136.067Ribosomal_S3Ae (PF01015, IPR001593): Ribosomal S3Ae family
109 RPS4Xinteractor750.83736.290KOW (PF00467, IPR005824, SM00739): KOW motif
Ribosomal_S4e (PF00900, IPR013845): Ribosomal family S4e
RS4NT (PF08071, IPR013843): RS4NT (NUC023) domain
S4 (PF01479, IPR002942, SM00363): S4 domain
40S_S4_C (PF16121, IPR032277): 40S ribosomal protein S4 C-terminus
110 RPS5interactor730.81965.523Ribosomal_S7 (PF00177, IPR023798): Ribosomal protein S7p/S5e
111 RPS6protein found in more fusions770.81551.820Ribosomal_S6e (PF01092, IPR001377): Ribosomal protein S6e
DUF4574 (PF15141, IPR027896): Domain of unknown function (DUF4574)
112 RPS7interactor730.82449.788Ribosomal_S7e (PF01251, IPR000554): Ribosomal protein S7e
113 RPS8interactor860.680394.314Ribosomal_S8e (PF01201, IPR022309): Ribosomal protein S8e
114 RPS9interactor700.86037.280Ribosomal_S4 (PF00163, IPR001912): Ribosomal protein S4/S9 N-terminal domain
S4 (PF01479, IPR002942, SM00363): S4 domain
115 RPSAinteractor780.773172.343Ribosomal_S2 (PF00318, IPR001865): Ribosomal protein S2
40S_SA_C (PF16122, IPR032281): 40S ribosomal protein SA C-terminus
116 SFNsuppressor320.789207.76414-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
117 SLC25A5interactor410.86665.910Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
118 SPI1suppressor21.0000Ets (PF00178, IPR000418, SM00413): Ets-domain
p47_phox_C (PF08944, IPR015039): NADPH oxidase subunit p47Phox, C terminal domain
119 STUB1suppressor100.25086.926U-box (PF04564, IPR003613, SM00504): U-box domain
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_20 (PF14561): Tetratricopeptide repeat
120 SUMO1interactor100.250188.732Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like
121 SYNCRIPinteractor240.59118.377RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Limkain-b1 (PF11608, IPR024582): Limkain b1
122 TFE3oncoprotein50.6674.217HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
DUF3371 (PF11851, IPR021802): Domain of unknown function (DUF3371)
MITF_TFEB_C_3_N (PF15951, IPR031867): MITF/TFEB/TFEC/TFE3 N-terminus
123 TFEBoncoprotein31.0000HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
DDRGK (PF09756, IPR019153, SM01128): DDRGK domain
DUF3371 (PF11851, IPR021802): Domain of unknown function (DUF3371)
MITF_TFEB_C_3_N (PF15951, IPR031867): MITF/TFEB/TFEC/TFE3 N-terminus
124 TFECinteractor40.3333.906HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
DUF3371 (PF11851, IPR021802): Domain of unknown function (DUF3371)
125 THOC2interactor21.0000Sec62 (PF03839, IPR004728): Translocation protein Sec62
Tho2 (PF11262, IPR021418): Transcription factor/nuclear export subunit protein 2
Thoc2 (PF11732, IPR021726): Transcription- and export-related complex subunit
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
THOC2_N (PF16134, IPR032302): THO complex subunit 2 N-terminus
126 UBA52interactor230.82210.408Ribosomal_L40e (PF01020, IPR001975): Ribosomal L40e family
VWC (PF00093, IPR001007, SM00214): von Willebrand factor type C domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
127 UBE2Iinteractor160.324348.396UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
128 UBE2V2interactor30.6676.786UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
129 UBL4Ainteractor630.82065.877ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
130 UCHL5oncoprotein150.85711.725Peptidase_C12 (PF01088, IPR001578): Ubiquitin carboxyl-terminal hydrolase, family 1
131 VCAM1interactor590.680235.092C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
132 XPO1interactor430.606837.596CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
133 ZUFSPinteractor100zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding
Peptidase_C78 (PF07910, IPR012462): Peptidase family C78
zf-C2H2_4 (PF13894): C2H2-type zinc finger

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