1 |
IMMP2L | parental protein | 1 | 0 | 0 | Peptidase_S24 (PF00717, IPR019759): Peptidase S24-like Peptidase_S26 (PF10502, IPR019533): Signal peptidase, peptidase S26 DUF2798 (PF11391, IPR021529): Protein of unknown function (DUF2798) |
2 |
RPS6KA3 | parental protein | 42 | 0.100 | 1309.516 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
3 |
ATP5J | interactor | 2 | 1.000 | 0 | ATP-synt_F6 (PF05511, IPR008387): Mitochondrial ATP synthase coupling factor 6 |
4 |
BARX1 | interactor | 1 | 0 | 0 | Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
5 |
CDC37 | protein found in more fusions | 8 | 0.667 | 5.000 | CDC37_C (PF08564, IPR013873, SM01069): Cdc37 C terminal domain CDC37_M (PF08565, IPR013874, SM01070): Cdc37 Hsp90 binding domain CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding Rho_Binding (PF08912, IPR015008): Rho Binding TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding |
6 |
CREBBP | suppressor | 8 | 0.524 | 9.141 | Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain MAS20 (PF02064, IPR002056): MAS20 protein import receptor TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26 HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) |
7 |
CSE1L | oncoprotein | 8 | 0.607 | 7.511 | CAS_CSE1 (PF03378, IPR005043): CAS/CSE protein, C-terminus Cse1 (PF08506, IPR013713): Cse1 IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein |
8 |
DFFA | suppressor | 2 | 1.000 | 0 | CIDE-N (PF02017, IPR003508): CIDE-N domain DFF-C (PF09033, IPR015121): DNA Fragmentation factor 45kDa, C terminal domain T2SSppdC (PF12528, IPR022204): Type II secretion prepilin peptidase dependent protein C SAPIS-gp6 (PF16722, IPR031999): Pathogenicity island protein gp6 in Staphylococcus |
9 |
EGFR | oncoprotein | 15 | 0.330 | 50.597 | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT) GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV |
10 |
EIF3C | oncoprotein | 2 | 1.000 | 0 | eIF-3c_N (PF05470, IPR008905): Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI (PF01399, IPR000717, SM00088): PCI domain |
11 |
ESR1 | suppressor | 11 | 0.489 | 31.380 | Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal |
12 |
FGFR1 | oncoprotein | 5 | 0.500 | 1.900 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase |
13 |
GBA | interactor | 5 | 0.600 | 3.971 | Glyco_hydro_30 (PF02055, IPR001139): Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C (PF17189): Glycosyl hydrolase family 30 beta sandwich domain |
14 |
GDA | interactor | 4 | 1.000 | 0 | Amidohydro_1 (PF01979, IPR006680): Amidohydrolase family |
15 |
H2AFX | suppressor | 7 | 0.429 | 25.883 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A |
16 |
HIST1H3A | interactor | 4 | 0.667 | 0.667 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
17 |
HMGN1 | interactor | 2 | 0 | 0 | HMG14_17 (PF01101, IPR000079, SM00527): HMG14 and HMG17 |
18 |
HNRNPD | oncoprotein | 8 | 0.286 | 90.817 | CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Keratin_2_head (PF16208, IPR032444): Keratin type II head |
19 |
HNRNPH1 | oncoprotein | 4 | 0.667 | 10.549 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger |
20 |
HSP90AA1 | oncoprotein | 12 | 0.491 | 19.450 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein |
21 |
HSPA8 | oncoprotein | 11 | 0.418 | 46.737 | HSP70 (PF00012, IPR013126): Hsp70 protein |
22 |
KIAA1456 | interactor | 1 | 0 | 0 | Methyltransf_11 (PF08241, IPR013216): Methyltransferase domain Methyltransf_23 (PF13489): Methyltransferase domain |
23 |
MAPK1 | oncoprotein | 10 | 0.528 | 14.864 | Pkinase (PF00069, IPR000719): Protein kinase domain |
24 |
MAPK14 | oncoprotein | 6 | 0.500 | 3.833 | Pkinase (PF00069, IPR000719): Protein kinase domain |
25 |
MAPK3 | oncoprotein | 7 | 0.667 | 3.167 | Pkinase (PF00069, IPR000719): Protein kinase domain |
26 |
MAPT | protein found in more fusions | 5 | 0.667 | 0.667 | Tubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeat |
27 |
MASP1 | interactor | 3 | 0.667 | 0.500 | CUB (PF00431, IPR000859, SM00042): CUB domain Sushi (PF00084, IPR000436, SM00032): Sushi repeat (SCR repeat) Trypsin (PF00089, IPR001254, SM00020): Trypsin FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site |
28 |
NAPRT | interactor | 3 | 0.667 | 1.571 | NAPRTase (PF04095, IPR007229): Nicotinate phosphoribosyltransferase (NAPRTase) family |
29 |
NEDD4 | suppressor | 6 | 0.600 | 2.833 | Rota_NS26 (PF01525, IPR002512): Rotavirus NS26 WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) |
30 |
NFATC1 | oncoprotein | 1 | 0 | 0 | RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain |
31 |
NFKBIA | oncoprotein | 3 | 0.667 | 0.500 | Ank (PF00023, IPR002110, SM00248): Ankyrin repeat Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) Ank_5 (PF13857): Ankyrin repeats (many copies) |
32 |
NPEPPS | interactor | 6 | 0.733 | 2.733 | Peptidase_M1 (PF01433, IPR014782): Peptidase family M1 ERAP1_C (PF11838, IPR024571): ERAP1-like C-terminal domain |
33 |
NTRK1 | oncoprotein | 20 | 0.263 | 148.044 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
34 |
PDPK1 | interactor | 3 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain PH_3 (PF14593): PH domain |
35 |
PEA15 | suppressor | 4 | 0.667 | 2.000 | DED (PF01335, IPR001875, SM00031): Death effector domain |
36 |
RASAL1 | suppressor | 2 | 1.000 | 0 | BTK (PF00779, IPR001562, SM00107): BTK motif C2 (PF00168, IPR000008, SM00239): C2 domain PH (PF00169, IPR001849, SM00233): PH domain RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase |
37 |
RPS6KA1 | oncoprotein | 12 | 0.379 | 33.740 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
38 |
SLC9A3R1 | suppressor | 8 | 0.714 | 3.844 | EBP50_C (PF09007, IPR015098): EBP50, C-terminal PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) |
39 |
SMS | interactor | 5 | 0.900 | 0.944 | Spermine_synth (PF01564, IPR001045): Spermine/spermidine synthase |
40 |
STIP1 | interactor | 5 | 1.000 | 0 | TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_17 (PF13431): Tetratricopeptide repeat Wtap (PF17098, IPR029732): WTAP/Mum2p family |
41 |
TGM2 | protein found in more fusions | 6 | 0.700 | 1.833 | Transglut_C (PF00927, IPR008958): Transglutaminase family, C-terminal ig like domain Transglut_N (PF00868, IPR001102): Transglutaminase family Transglut_core (PF01841, IPR002931, SM00460): Transglutaminase-like superfamily |
42 |
TMEM139 | interactor | 1 | 0 | 0 | TMEM51 (PF15345, IPR029265): Transmembrane protein 51 |
43 |
TRAF2 | interactor | 3 | 1.000 | 0 | MATH (PF00917, IPR002083, SM00061): MATH domain Sina (PF03145, IPR018121): Seven in absentia protein family SlyX (PF04102, IPR007236): SlyX zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain zf-C3HC4_5 (PF17121, IPR001841): Zinc finger, C3HC4 type (RING finger) |
44 |
YBX1 | oncoprotein | 6 | 0.733 | 13.807 | CSD (PF00313, IPR002059): 'Cold-shock' DNA-binding domain PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2 |
45 |
ZMYM5 | interactor | 1 | 0 | 0 | DUF2116 (PF09889, IPR019216): Uncharacterized protein containing a Zn-ribbon (DUF2116) zf-FCS (PF06467, IPR010507): MYM-type Zinc finger with FCS sequence motif V-ATPase_H_C (PF11698, IPR011987): V-ATPase subunit H zinc_ribbon_2 (PF13240, IPR026870): zinc-ribbon domain |