1 |
RPS6 | parental protein | 193 | 0.343 | 5055.709 | Ribosomal_S6e (PF01092, IPR001377): Ribosomal protein S6e DUF4574 (PF15141, IPR027896): Domain of unknown function (DUF4574) |
2 |
PARD6G | parental protein | 17 | 0.213 | 563.502 | PB1 (PF00564, IPR000270, SM00666): PB1 domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) |
3 |
ARRB2 | interactor | 59 | 0.550 | 148.694 | Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain |
4 |
ATF4 | oncoprotein | 4 | 0.667 | 0.511 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor |
5 |
BRINP1 | suppressor | 5 | 0.300 | 18.793 | MACPF (PF01823, IPR020864, SM00457): MAC/Perforin domain |
6 |
CAND1 | interactor | 118 | 0.573 | 297.029 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981) HEAT (PF02985, IPR000357): HEAT repeat TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20) RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II |
7 |
CBX8 | interactor | 22 | 0.590 | 58.702 | Atrophin-1 (PF03154, IPR002951): Atrophin-1 family Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain RBR (PF17208): RNA binding Region CBX7_C (PF17218): CBX family C-terminal motif |
8 |
CD81 | interactor | 48 | 0.723 | 26.056 | Tetraspannin (PF00335, IPR018499): Tetraspanin family |
9 |
CDC42 | oncoprotein | 8 | 0.333 | 48.385 | Ras (PF00071, IPR001806, SM00173): Ras family |
10 |
CEP250 | interactor | 60 | 0.769 | 43.652 | ACCA (PF03255, IPR001095): Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DASH_Dam1 (PF08653, IPR013962): DASH complex subunit Dam1 DivIC (PF04977, IPR007060): Septum formation initiator DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) EHN (PF06441, IPR010497): Epoxide hydrolase N terminus ERM (PF00769, IPR011259): Ezrin/radixin/moesin family Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family IncA (PF04156, IPR007285): IncA protein Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain SlyX (PF04102, IPR007236): SlyX Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal TSC22 (PF01166, IPR000580): TSC-22/dip/bun family CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Endonuc_Holl (PF10107, IPR019287): Endonuclease related to archaeal Holliday junction resolvase DUF2570 (PF10828, IPR022538): Protein of unknown function (DUF2570) DGF-1_C (PF11040, IPR021053): Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968) DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404) DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472) Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion KAsynt_C_assoc (PF16197, IPR032821): Ketoacyl-synthetase C-terminal extension HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 |
11 |
CLINT1 | protein found in more fusions | 9 | 0.571 | 0.600 | ENTH (PF01417, IPR001026, SM00273): ENTH domain |
12 |
COPS5 | protein found in more fusions | 105 | 0.615 | 182.898 | JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease |
13 |
CRY2 | protein found in more fusions | 19 | 0.542 | 4.914 | DNA_photolyase (PF00875, IPR006050): DNA photolyase FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase |
14 |
CUL1 | suppressor | 109 | 0.577 | 252.721 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
15 |
CUL2 | suppressor | 74 | 0.682 | 111.428 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
16 |
CUL3 | protein found in more fusions | 117 | 0.534 | 543.029 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal |
17 |
CUL4B | oncoprotein | 62 | 0.654 | 86.578 | Cullin (PF00888, IPR001373, SM00182): Cullin family EBP50_C (PF09007, IPR015098): EBP50, C-terminal Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain PG_binding_4 (PF12229, IPR022029): Putative peptidoglycan binding domain MDFI (PF15316, IPR026134): MyoD family inhibitor |
18 |
CUL5 | suppressor | 75 | 0.667 | 86.959 | Cullin (PF00888, IPR001373, SM00182): Cullin family GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
19 |
CUL7 | protein found in more fusions | 79 | 0.546 | 174.909 | ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7 |
20 |
DCC | suppressor | 12 | 0.803 | 1.601 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain Neogenin_C (PF06583, IPR010560): Neogenin C-terminus DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) Ig_3 (PF13927): Immunoglobulin domain EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain |
21 |
DCUN1D1 | interactor | 34 | 0.749 | 10.275 | Cullin_binding (PF03556, IPR005176): Cullin binding UBA_4 (PF14555): UBA-like domain |
22 |
DDX18 | interactor | 37 | 0.688 | 14.284 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase NPR3 (PF03666, IPR005365): Nitrogen Permease regulator of amino acid transport activity 3 Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain DUF4217 (PF13959, IPR025313, SM01178): Domain of unknown function (DUF4217) |
23 |
DHX9 | oncoprotein | 51 | 0.511 | 62.738 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold T2SSE (PF00437, IPR001482): Type II/IV secretion system protein HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
24 |
EBNA1BP2 | interactor | 35 | 0.739 | 10.237 | Ebp2 (PF05890, IPR008610): Eukaryotic rRNA processing protein EBP2 |
25 |
EEF1A1 | suppressor | 84 | 0.564 | 251.941 | GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain |
26 |
EEF2 | interactor | 57 | 0.630 | 52.579 | EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 EFG_II (PF14492, IPR009022): Elongation Factor G, domain II |
27 |
EIF2A | interactor | 16 | 0.600 | 18.099 | Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A |
28 |
EIF3B | interactor | 25 | 0.187 | 70.965 | eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A PD40 (PF07676, IPR011659): WD40-like Beta Propeller Repeat RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PGBA_C (PF15437, IPR032737): Plasminogen-binding protein pgbA C-terminal PALB2_WD40 (PF16756, IPR031920): Partner and localizer of BRCA2 WD40 domain Methyltr_RsmF_N (PF17125, IPR031341): N-terminal domain of 16S rRNA methyltransferase RsmF |
29 |
EIF3CL | interactor | 22 | 0.766 | 5.544 | eIF-3c_N (PF05470, IPR008905): Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI (PF01399, IPR000717, SM00088): PCI domain |
30 |
EIF4A3 | interactor | 53 | 0.650 | 37.682 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
31 |
EIF5 | interactor | 8 | 0.643 | 4.233 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Hist_rich_Ca-bd (PF10529, IPR019552): Histidine-rich Calcium-binding repeat region eIF-5_eIF-2B (PF01873, IPR002735, SM00653): Domain found in IF2B/IF5 W2 (PF02020, IPR003307, SM00515): eIF4-gamma/eIF5/eIF2-epsilon |
32 |
EIF5B | interactor | 11 | 0.600 | 1.190 | GAGA_bind (PF06217, IPR010409): GAGA binding protein-like family DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 MIase (PF02426, IPR026029): Muconolactone delta-isomerase NOA36 (PF06524, IPR010531): NOA36 protein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306) IF-2 (PF11987, IPR023115): Translation-initiation factor 2 DUF3807 (PF12720, IPR024526): Protein of unknown function (DUF3807) GTP_EFTU_D4 (PF14578, IPR029459): Elongation factor Tu domain 4 DUF4632 (PF15451, IPR027952): Domain of unknown function (DUF4632) Coilin_N (PF15862, IPR031722): Coilin N-terminus DUF4820 (PF16091, IPR032150): Domain of unknown function (DUF4820) |
33 |
EIF6 | interactor | 40 | 0.687 | 24.306 | eIF-6 (PF01912, IPR002769, SM00654): eIF-6 family |
34 |
ESR1 | suppressor | 88 | 0.554 | 336.091 | Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal |
35 |
FAU | interactor | 45 | 0.785 | 14.669 | Ribosomal_S30 (PF04758, IPR006846): Ribosomal protein S30 ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
36 |
FBL | interactor | 61 | 0.627 | 84.484 | Fibrillarin (PF01269, IPR000692): Fibrillarin |
37 |
FBXO6 | interactor | 44 | 0.483 | 61.268 | FBA (PF04300, IPR007397): F-box associated region F-box-like (PF12937, IPR001810): F-box-like |
38 |
FN1 | oncoprotein | 103 | 0.552 | 435.284 | fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) |
39 |
FRS2 | interactor | 3 | 0.333 | 2.783 | IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type) |
40 |
GAN | protein found in more fusions | 32 | 0.615 | 19.343 | BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif Kelch_3 (PF13415): Galactose oxidase, central domain Kelch_5 (PF13854): Kelch motif |
41 |
GNL3 | interactor | 46 | 0.750 | 17.115 | GN3L_Grn1 (PF08701, IPR014813): GNL3L/Grn1 putative GTPase GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain MMR_HSR1 (PF01926, IPR006073): 50S ribosome-binding GTPase Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family FAM176 (PF14851): FAM176 family |
42 |
HDAC6 | oncoprotein | 9 | 0.643 | 5.361 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain PSGP (PF07276, IPR009900): Apopolysialoglycoprotein (PSGP) zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein |
43 |
HIST1H2AD | interactor | 16 | 0.817 | 1.108 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A |
44 |
HNRNPA0 | interactor | 30 | 0.607 | 9.478 | SAP130_C (PF16014, IPR031963): Histone deacetylase complex subunit SAP130 C-terminus |
45 |
HNRNPA1 | interactor | 69 | 0.399 | 477.992 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1 |
46 |
HNRNPM | interactor | 77 | 0.581 | 103.215 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNP_M (PF11532, IPR024666): Heterogeneous nuclear ribonucleoprotein M Collagen_mid (PF15984, IPR031929): Bacterial collagen, middle region |
47 |
HNRNPU | protein found in more fusions | 126 | 0.519 | 400.719 | CDC45 (PF02724, IPR003874): CDC45-like protein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SAP (PF02037, IPR003034, SM00513): SAP domain SPRY (PF00622, IPR003877, SM00449): SPRY domain AAA_33 (PF13671): AAA domain WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
48 |
HSP90AA1 | oncoprotein | 63 | 0.447 | 294.987 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein |
49 |
HSP90AB1 | oncoprotein | 59 | 0.458 | 145.667 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein |
50 |
HSPA4 | interactor | 29 | 0.360 | 261.356 | Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region HSP70 (PF00012, IPR013126): Hsp70 protein TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5 |
51 |
ICAM1 | oncoprotein | 53 | 0.779 | 25.533 | Adhes-Ig_like (PF09085, IPR015169): Adhesion molecule, immunoglobulin-like C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain ICAM_N (PF03921, IPR013768): Intercellular adhesion molecule (ICAM), N-terminal domain Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain |
52 |
IGSF8 | oncoprotein | 56 | 0.752 | 30.906 | V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain |
53 |
ILF2 | interactor | 71 | 0.639 | 76.544 | DZF (PF07528, IPR006561, SM00572): DZF domain |
54 |
ILF3 | oncoprotein | 85 | 0.650 | 109.726 | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif DZF (PF07528, IPR006561, SM00572): DZF domain |
55 |
IMPDH2 | protein found in more fusions | 17 | 0.358 | 13.021 | IMPDH (PF00478, IPR001093): IMP dehydrogenase / GMP reductase domain |
56 |
ITGA4 | interactor | 79 | 0.641 | 133.793 | FG-GAP (PF01839, IPR013517): FG-GAP repeat Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region Integrin_alpha2 (PF08441, IPR013649): Integrin alpha |
57 |
KIF11 | protein found in more fusions | 16 | 0.467 | 65.373 | Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus COG2 (PF06148, IPR024602): COG (conserved oligomeric Golgi) complex component, COG2 DUF106 (PF01956, IPR002809): Integral membrane protein DUF106 DUF16 (PF01519, IPR002862): Protein of unknown function DUF16 Gag_p17 (PF00540, IPR000071): gag gene protein p17 (matrix protein) Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein KxDL (PF10241, IPR019371): Uncharacterized conserved protein Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain DUF3510 (PF12022, IPR024603): Domain of unknown function (DUF3510) Microtub_bind (PF13931, IPR025901): Kinesin-associated microtubule-binding |
58 |
LLGL1 | suppressor | 9 | 0.444 | 42.917 | Lgl_C (PF08596, IPR013905): Lethal giant larvae(Lgl) like, C-terminal LLGL (PF08366, IPR013577): LLGL2 WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
59 |
LLGL2 | interactor | 8 | 0.286 | 29.617 | Lgl_C (PF08596, IPR013905): Lethal giant larvae(Lgl) like, C-terminal LLGL (PF08366, IPR013577): LLGL2 WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N (PF14655, IPR032839): Rab3 GTPase-activating protein regulatory subunit N-terminus |
60 |
LOC101929876 | interactor | 62 | 0.939 | 5.197 | NA |
61 |
MAGOH | interactor | 38 | 0.670 | 35.963 | Mago_nashi (PF02792, IPR004023): Mago nashi protein |
62 |
MAPKAP1 | interactor | 7 | 0.667 | 2.424 | SIN1 (PF05422, IPR008828): Stress-activated map kinase interacting protein 1 (SIN1) CRIM (PF16978, IPR031567): SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH (PF16979, IPR031313): SAPK-interacting protein 1 (Sin1), Pleckstrin-homology |
63 |
MARK2 | protein found in more fusions | 10 | 0.556 | 24.876 | DUF702 (PF05142, IPR007818): Domain of unknown function (DUF702) KA1 (PF02149, IPR001772): Kinase associated domain 1 Pkinase (PF00069, IPR000719): Protein kinase domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain |
64 |
MDM2 | oncoprotein | 49 | 0.441 | 246.965 | Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region Presenilin (PF01080, IPR001108): Presenilin SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
65 |
MTOR | oncoprotein | 18 | 0.419 | 81.680 | DUF1104 (PF06518, IPR009488): Protein of unknown function (DUF1104) EPSP_synthase (PF00275, IPR001986): EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain HEAT (PF02985, IPR000357): HEAT repeat FRB_dom (PF08771, IPR009076): FKBP12-rapamycin binding domain V-ATPase_H_N (PF03224, IPR004908): V-ATPase subunit H PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats TPR_19 (PF14559): Tetratricopeptide repeat |
66 |
MYBBP1A | suppressor | 42 | 0.722 | 16.289 | DNA_pol_phi (PF04931, IPR007015): DNA polymerase phi Pol_alpha_B_N (PF08418, IPR013627): DNA polymerase alpha subunit B N-terminal |
67 |
NAP1L1 | protein found in more fusions | 34 | 0.723 | 15.159 | NAP (PF00956, IPR002164): Nucleosome assembly protein (NAP) RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31 PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term |
68 |
NCL | protein found in more fusions | 76 | 0.508 | 259.238 | DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Myc_N (PF01056, IPR012682): Myc amino-terminal region RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YL1 (PF05764, IPR008895): YL1 nuclear protein Limkain-b1 (PF11608, IPR024582): Limkain b1 |
69 |
NDRG1 | suppressor | 22 | 0.645 | 7.398 | Ndr (PF03096, IPR004142): Ndr family |
70 |
NFIA | interactor | 11 | 0.691 | 1.209 | CTF_NFI (PF00859, IPR000647): CTF/NF-I family transcription modulation region NfI_DNAbd_pre-N (PF10524, IPR019548): Nuclear factor I protein pre-N-terminus MH1 (PF03165, IPR003619, SM00523): MH1 domain |
71 |
NIFK | interactor | 42 | 0.674 | 42.073 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) hNIFK_binding (PF12196, IPR021043): FHA Ki67 binding domain of hNIFK |
72 |
NOLC1 | interactor | 27 | 0.652 | 128.958 | DTHCT (PF08070, IPR012542): DTHCT (NUC029) region SRP40_C (PF05022, IPR007718): SRP40, C-terminal domain Stm1_N (PF09598, IPR019084): Stm1 stn_TNFRSF12A (PF12191, IPR022316): Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain NST1 (PF13945, IPR025279): Salt tolerance down-regulator SEEEED (PF14797, IPR029394): Serine-rich region of AP3B1, clathrin-adaptor complex DUF4611 (PF15387, IPR027893): Domain of unknown function (DUF4611) PAF (PF15715, IPR031444): PCNA-associated factor IMUP (PF15761, IPR026621): Immortalisation up-regulated protein NuDC (PF16273, IPR032572): Nuclear distribution C domain PHC2_SAM_assoc (PF16616): Unstructured region on Polyhomeotic-like protein 1 and 2 |
73 |
NOP2 | interactor | 51 | 0.705 | 40.460 | BSP_II (PF05432, IPR008412): Bone sialoprotein II (BSP-II) Methyltr_RsmB-F (PF01189, IPR001678): 16S rRNA methyltransferase RsmB/F P120R (PF08062, IPR012586): P120R (NUC006) repeat Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein DUF2477 (PF10631, IPR018904): Protein of unknown function (DUF2477) FAM176 (PF14851): FAM176 family Methyltr_RsmF_N (PF17125, IPR031341): N-terminal domain of 16S rRNA methyltransferase RsmF |
74 |
NOP56 | interactor | 87 | 0.649 | 428.016 | Cytochrom_NNT (PF03264, IPR005126): NapC/NirT cytochrome c family, N-terminal region Nop (PF01798, IPR002687): snoRNA binding domain, fibrillarin NOP5NT (PF08156, IPR012974): NOP5NT (NUC127) domain RNA_polI_A34 (PF08208, IPR013240): DNA-directed RNA polymerase I subunit RPA34.5 SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal |
75 |
NOP58 | protein found in more fusions | 42 | 0.729 | 16.537 | Cellulose_synt (PF03552, IPR005150): Cellulose synthase Nop (PF01798, IPR002687): snoRNA binding domain, fibrillarin NOP5NT (PF08156, IPR012974): NOP5NT (NUC127) domain Selenoprotein_S (PF06936, IPR009703): Selenoprotein S (SelS) |
76 |
NOP9 | interactor | 6 | 0.667 | 0.816 | PUF (PF00806, IPR001313, SM00025): Pumilio-family RNA binding repeat |
77 |
NPM1 | suppressor | 130 | 0.485 | 1172.731 | Nucleoplasmin (PF03066): Nucleoplasmin/nucleophosmin domain SDA1 (PF05285, IPR007949): SDA1 NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain |
78 |
NTRK1 | oncoprotein | 95 | 0.376 | 1024.349 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
79 |
OBSL1 | interactor | 58 | 0.548 | 80.229 | BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain |
80 |
PABPC1 | oncoprotein | 73 | 0.577 | 116.830 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain YflT (PF11181, IPR025889): Heat induced stress protein YflT |
81 |
PAN2 | interactor | 84 | 0.676 | 140.452 | RNase_T (PF00929, IPR013520): Exonuclease UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase WD40_like (PF17005, IPR031544): WD40-like domain |
82 |
PARD3 | interactor | 13 | 0.385 | 77.850 | PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) DUF3534 (PF12053, IPR021922): Domain of unknown function (DUF3534) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term |
83 |
PARD6B | interactor | 12 | 0.364 | 63.765 | PB1 (PF00564, IPR000270, SM00666): PB1 domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) |
84 |
PARK2 | suppressor | 44 | 0.471 | 140.337 | IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
85 |
PCK1 | interactor | 10 | 0.933 | 0.108 | PEPCK (PF00821, IPR008209): Phosphoenolpyruvate carboxykinase |
86 |
PLA2G12A | interactor | 2 | 1.000 | 0 | PLA2G12 (PF06951, IPR010711): Group XII secretory phospholipase A2 precursor (PLA2G12) |
87 |
PNMA2 | interactor | 4 | 0.167 | 22.741 | PNMA (PF14893, IPR026523): PNMA |
88 |
PNMA3 | interactor | 3 | 0 | 16.049 | zf-CCHC (PF00098, IPR001878): Zinc knuckle PNMA (PF14893, IPR026523): PNMA |
89 |
PNMAL1 | interactor | 1 | 0 | 0 | PNMA (PF14893, IPR026523): PNMA |
90 |
PNO1 | interactor | 26 | 0.732 | 9.591 | KH_1 (PF00013, IPR004088, SM00322): KH domain |
91 |
POT1 | interactor | 13 | 0.470 | 8.529 | POT1 (PF02765, IPR011564, SM00976): Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain POT1PC (PF16686, IPR032042): ssDNA-binding domain of telomere protection protein |
92 |
PRKACB | interactor | 6 | 0.733 | 0.227 | Pkinase (PF00069, IPR000719): Protein kinase domain |
93 |
PRKCI | interactor | 14 | 0.407 | 78.832 | PB1 (PF00564, IPR000270, SM00666): PB1 domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
94 |
PRKCSH | interactor | 5 | 0.400 | 0.324 | CDC45 (PF02724, IPR003874): CDC45-like protein Ax_dynein_light (PF10211, IPR019347): Axonemal dynein light chain PRKCSH-like (PF12999, IPR028146): Glucosidase II beta subunit-like PRKCSH_1 (PF13015, IPR009011): Glucosidase II beta subunit-like protein EF-hand_5 (PF13202, IPR002048): EF hand |
95 |
PRKCZ | interactor | 14 | 0.410 | 84.432 | PB1 (PF00564, IPR000270, SM00666): PB1 domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
96 |
PTEN | suppressor | 35 | 0.714 | 171.945 | DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein |
97 |
PTOV1 | interactor | 6 | 0.400 | 5.252 | Med25 (PF11232, IPR021394): Mediator complex subunit 25 PTOV activation and synapsin 2 |
98 |
PYM1 | interactor | 33 | 0.797 | 13.637 | CcmD (PF04995, IPR007078): Heme exporter protein D (CcmD) Mago-bind (PF09282, IPR015362): Mago binding AAA_23 (PF13476): AAA domain |
99 |
RAC1 | oncoprotein | 10 | 0.306 | 63.319 | Ras (PF00071, IPR001806, SM00173): Ras family |
100 |
RACK1 | suppressor | 59 | 0.636 | 438.505 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
101 |
RAD21 | oncoprotein | 39 | 0.727 | 16.674 | Rad21_Rec8 (PF04824, IPR006909): Conserved region of Rad21 / Rec8 like protein Rad21_Rec8_N (PF04825, IPR006910): N terminus of Rad21 / Rec8 like protein FAM176 (PF14851): FAM176 family WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
102 |
RICTOR | interactor | 15 | 0.543 | 17.241 | RasGEF_N_2 (PF14663, IPR029453): Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_N (PF14664, IPR028267): Rapamycin-insensitive companion of mTOR, N-term RICTOR_phospho (PF14665, IPR029259): Rapamycin-insensitive companion of mTOR, phosphorylation-site RICTOR_M (PF14666, IPR029451): Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V (PF14668, IPR029452): Rapamycin-insensitive companion of mTOR, domain 5 |
103 |
RPL10 | suppressor | 114 | 0.628 | 203.640 | Ribosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e |
104 |
RPL10A | interactor | 109 | 0.689 | 126.616 | Ribosomal_L1 (PF00687, IPR028364): Ribosomal protein L1p/L10e family |
105 |
RPL10L | interactor | 67 | 0.886 | 21.178 | Ribosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e Cytochrome_P460 (PF16694, IPR032033): Cytochrome P460 |
106 |
RPL11 | suppressor | 122 | 0.616 | 213.552 | Ribosomal_L5 (PF00281, IPR002132): Ribosomal protein L5 Ribosomal_L5_C (PF00673, IPR002132): ribosomal L5P family C-terminus |
107 |
RPL12 | protein found in more fusions | 108 | 0.693 | 107.881 | Ribosomal_L11 (PF00298, IPR020783): Ribosomal protein L11, RNA binding domain Ribosomal_L11_N (PF03946, IPR020784): Ribosomal protein L11, N-terminal domain |
108 |
RPL13 | interactor | 114 | 0.614 | 295.409 | Ribosomal_L13e (PF01294, IPR001380): Ribosomal protein L13e |
109 |
RPL13A | interactor | 88 | 0.782 | 49.283 | Ribosomal_L13 (PF00572, IPR005822): Ribosomal protein L13 |
110 |
RPL14 | interactor | 121 | 0.620 | 208.954 | KOW (PF00467, IPR005824, SM00739): KOW motif Ribosomal_L14e (PF01929, IPR002784): Ribosomal protein L14 UPF0688 (PF15772, IPR031530): UPF0688 family |
111 |
RPL15 | interactor | 116 | 0.644 | 214.242 | Ribosomal_L15e (PF00827, IPR000439): Ribosomal L15 |
112 |
RPL17 | interactor | 99 | 0.681 | 99.748 | Ribosomal_L22 (PF00237, IPR001063): Ribosomal protein L22p/L17e |
113 |
RPL18 | interactor | 121 | 0.637 | 174.340 | Ribosomal_L18 (PF17135): Ribosomal protein 60S L18 and 50S L18e |
114 |
RPL18A | interactor | 102 | 0.691 | 119.306 | Ribosomal_L18A (PF01775, IPR023573): Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A |
115 |
RPL19 | interactor | 117 | 0.638 | 173.719 | DUF1682 (PF07946, IPR012879): Protein of unknown function (DUF1682) Ribosomal_L19e (PF01280, IPR000196): Ribosomal protein L19e |
116 |
RPL21 | interactor | 112 | 0.694 | 107.106 | Ribosomal_L21e (PF01157, IPR001147): Ribosomal protein L21e |
117 |
RPL22 | oncoprotein | 100 | 0.732 | 159.636 | Ribosomal_L22e (PF01776, IPR002671): Ribosomal L22e protein family |
118 |
RPL23 | interactor | 120 | 0.589 | 513.000 | Ribosomal_L14 (PF00238, IPR000218): Ribosomal protein L14p/L23e |
119 |
RPL23A | interactor | 125 | 0.585 | 367.378 | Ribosomal_L23 (PF00276, IPR013025): Ribosomal protein L23 Ribosomal_L23eN (PF03939, IPR005633): Ribosomal protein L23, N-terminal domain |
120 |
RPL24 | protein found in more fusions | 109 | 0.683 | 123.983 | MAS20 (PF02064, IPR002056): MAS20 protein import receptor Ribosomal_L24e (PF01246, IPR000988): Ribosomal protein L24e |
121 |
RPL26 | oncoprotein | 67 | 0.682 | 77.496 | TP2 (PF01254, IPR000678): Nuclear transition protein 2 Ribosomal_L26 (PF16906, IPR005756): Ribosomal proteins L26 eukaryotic, L24P archaeal |
122 |
RPL26L1 | interactor | 54 | 0.739 | 22.978 | Ribosomal_L26 (PF16906, IPR005756): Ribosomal proteins L26 eukaryotic, L24P archaeal |
123 |
RPL27 | protein found in more fusions | 95 | 0.759 | 65.004 | Ribosomal_L27e (PF01777, IPR001141): Ribosomal L27e protein family |
124 |
RPL27A | interactor | 98 | 0.711 | 152.750 | Ribosomal_L27A (PF00828, IPR021131): Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A |
125 |
RPL28 | interactor | 52 | 0.679 | 70.125 | Ribosomal_L28e (PF01778, IPR029004): Ribosomal L28e protein family |
126 |
RPL29 | interactor | 42 | 0.818 | 26.290 | BRF1 (PF07741, IPR011665): Brf1-like TBP-binding domain Ribosomal_L29e (PF01779, IPR002673): Ribosomal L29e protein family |
127 |
RPL3 | protein found in more fusions | 108 | 0.686 | 207.631 | Ribosomal_L3 (PF00297, IPR000597): Ribosomal protein L3 |
128 |
RPL30 | protein found in more fusions | 96 | 0.739 | 71.023 | NCBP3 (PF10309, IPR019416): Nuclear cap-binding protein subunit 3 |
129 |
RPL31 | interactor | 106 | 0.679 | 116.110 | Ribosomal_L31e (PF01198, IPR000054): Ribosomal protein L31e |
130 |
RPL32 | interactor | 62 | 0.831 | 26.650 | Ribosomal_L32e (PF01655, IPR001515): Ribosomal protein L32 |
131 |
RPL34 | interactor | 64 | 0.863 | 16.425 | Redoxin (PF08534, IPR013740): Redoxin Ribosomal_L34e (PF01199, IPR008195): Ribosomal protein L34e |
132 |
RPL35 | interactor | 89 | 0.786 | 48.162 | Ribosomal_L29 (PF00831, IPR001854): Ribosomal L29 protein XFP_N (PF09364, IPR018970): XFP N-terminal domain |
133 |
RPL35A | interactor | 67 | 0.886 | 12.573 | Ribosomal_L35Ae (PF01247, IPR001780): Ribosomal protein L35Ae |
134 |
RPL36 | interactor | 88 | 0.807 | 39.456 | Ribosomal_L36e (PF01158, IPR000509): Ribosomal protein L36e |
135 |
RPL37A | interactor | 102 | 0.664 | 181.109 | Ribosomal_L37ae (PF01780, IPR002674): Ribosomal L37ae protein family |
136 |
RPL38 | protein found in more fusions | 82 | 0.816 | 47.602 | Ribosomal_L38e (PF01781, IPR002675): Ribosomal L38e protein family |
137 |
RPL3L | interactor | 34 | 0.998 | 0.032 | Ribosomal_L3 (PF00297, IPR000597): Ribosomal protein L3 |
138 |
RPL4 | interactor | 132 | 0.571 | 338.523 | Ribosomal_L4 (PF00573, IPR002136): Ribosomal protein L4/L1 family Ribos_L4_asso_C (PF14374, IPR025755): 60S ribosomal protein L4 C-terminal domain |
139 |
RPL5 | suppressor | 140 | 0.538 | 539.924 | Ribosomal_L18_c (PF14204, IPR025607): Ribosomal L18 C-terminal region Ribosomal_L5e (PF17144): Ribosomal large subunit proteins 60S L5, and 50S L18 |
140 |
RPL6 | protein found in more fusions | 136 | 0.560 | 331.468 | Ribosomal_L6e (PF01159, IPR000915): Ribosomal protein L6e Ribosomal_L6e_N (PF03868, IPR005568): Ribosomal protein L6, N-terminal domain |
141 |
RPL7 | interactor | 124 | 0.607 | 226.726 | Ribosomal_L30 (PF00327, IPR016082): Ribosomal protein L30p/L7e Ribosomal_L30_N (PF08079, IPR012988): Ribosomal L30 N-terminal domain |
142 |
RPL7A | protein found in more fusions | 115 | 0.644 | 156.586 | Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family |
143 |
RPL8 | interactor | 116 | 0.626 | 198.012 | Ribosomal_L2 (PF00181, IPR022666): Ribosomal Proteins L2, RNA binding domain Ribosomal_L2_C (PF03947, IPR022669): Ribosomal Proteins L2, C-terminal domain |
144 |
RPL9 | interactor | 112 | 0.665 | 471.790 | Ribosomal_L6 (PF00347, IPR020040): Ribosomal protein L6 |
145 |
RPLP0 | interactor | 119 | 0.624 | 283.999 | Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Ribosomal_L10 (PF00466, IPR001790): Ribosomal protein L10 |
146 |
RPLP0P6 | interactor | 74 | 0.748 | 69.508 | NA |
147 |
RPLP1 | interactor | 75 | 0.857 | 17.743 | Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein |
148 |
RPLP2 | protein found in more fusions | 94 | 0.746 | 62.781 | Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein |
149 |
RPS10 | interactor | 99 | 0.704 | 125.167 | S10_plectin (PF03501, IPR005326): Plectin/S10 domain |
|