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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins RPL18, SYNGR1 (from a repository: Fri Aug 2 10:50:15 2019)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)165
The number (and %) of the onco-proteins44 (26.67 %)
The number (and %) of the tumor suppressors21 (12.73 %)
Total number of binary PPIs (saturation %)5746 (42.47 %)
The number (and %) of affected PPIs163 (2.84 %)
The number of possible different fusions38
PPI diameter5
PPI radius3
The average degree of PPI69.152
Assortativity coefficient-0.0712
The network average Clustering coefficient0.690
The number (and %) of a zero Clustering coefficients3 (1.82 %)
The number (and %) of a zero Betweenness Centrality3 (1.82 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: SYNGR1,RPL18 All fusions
Proteins found in more fusions U2AF2 (see 2 fusions); FANCA (see 1 fusions); HNRNPU/RPL24 (see 1 fusions); RPLP2 (see 1 fusions); RPS24/RPS23 (see 1 fusions); RPS24/RPS27 (see 1 fusions); RPL27/RPS6 (see 1 fusions); HUWE1 (see 4 fusions); EEF1D (see 8 fusions); RPL38/RPL3 (see 1 fusions); NCL (see 4 fusions); RPS19/RPS14 (see 1 fusions); EEF1A1 (see 6 fusions); NTRK1/RPL7A (see 1 fusions); CUL3 (see 1 fusions); MRPL12 (see 1 fusions); RPLP0/RPLP0P6 (see 10 fusions); COPS5 (see 1 fusions); TP53 (see 3 fusions); RPL5 (see 1 fusions); FN1/RPL6 (see 1 fusions); NPM1 (see 1 fusions); CUL1 (see 3 fusions); CENPQ (see 1 fusions); RPA1 (see 1 fusions); NF2 (see 1 fusions); RPL3/RPL13A (see 1 fusions); ATP5A1 (see 1 fusions); STAU1 (see 2 fusions); CUL7 (see 2 fusions); SKI (see 1 fusions); RPL37A/RPS24 (see 1 fusions); NUDT21 (see 2 fusions); SFN (see 1 fusions); PABPC1 (see 3 fusions); ATP5A1/HUWE1 (see 2 fusions); MCM2 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 SYNGR1parental protein30328.000MARVEL (PF01284, IPR008253): Membrane-associating domain
2 RPL18parental protein1600.4351814.928Ribosomal_L18 (PF17135): Ribosomal protein 60S L18 and 50S L18e
3 ACTA2interactor230.6095.308Actin (PF00022, IPR004000, SM00268): Actin
4 ARRB2interactor480.71825.217Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
5 ATP5A1protein found in more fusions290.50518.576ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain
ATP-synt_ab_C (PF00306, IPR000793): ATP synthase alpha/beta chain, C terminal domain
ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain
6 ATP5Binteractor280.444214.918AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain
ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain
NACHT (PF05729): NACHT domain
7 CAND1interactor1080.636198.907Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981)
HEAT (PF02985, IPR000357): HEAT repeat
TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20)
RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
8 CCDC8interactor510.64646.201Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
PNMA (PF14893, IPR026523): PNMA
9 CD4suppressor150.6487.126ATP1G1_PLM_MAT8 (PF02038, IPR000272): ATP1G1/PLM/MAT8 family
C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
CD4-extracel (PF09191, IPR015274): CD4, extracellular
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
Tcell_CD4_C (PF12104, IPR021963): T cell CD4 receptor C terminal region
10 CDK2suppressor800.637105.834Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
11 CDKN1Asuppressor160.7422.748CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor
12 CENPQprotein found in more fusions71.0000CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit
13 CEP250interactor570.83919.585ACCA (PF03255, IPR001095): Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
DASH_Dam1 (PF08653, IPR013962): DASH complex subunit Dam1
DivIC (PF04977, IPR007060): Septum formation initiator
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
EHN (PF06441, IPR010497): Epoxide hydrolase N terminus
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
IncA (PF04156, IPR007285): IncA protein
Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain
SlyX (PF04102, IPR007236): SlyX
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
Endonuc_Holl (PF10107, IPR019287): Endonuclease related to archaeal Holliday junction resolvase
DUF2570 (PF10828, IPR022538): Protein of unknown function (DUF2570)
DGF-1_C (PF11040, IPR021053): Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus
DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968)
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472)
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
KAsynt_C_assoc (PF16197, IPR032821): Ketoacyl-synthetase C-terminal extension
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
14 COPS5protein found in more fusions970.666464.677JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
15 COPS6interactor400.633276.712DUF320 (PF03777, IPR005528): Small secreted domain (DUF320)
JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function
16 CREB3interactor40.333512.026bZIP_1 (PF00170, IPR004827): bZIP transcription factor
GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor
17 CUL1suppressor1030.621179.190Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
18 CUL2suppressor650.77036.324Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
19 CUL3protein found in more fusions1070.585326.803Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
20 CUL4Boncoprotein580.73429.388Cullin (PF00888, IPR001373, SM00182): Cullin family
EBP50_C (PF09007, IPR015098): EBP50, C-terminal
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
PG_binding_4 (PF12229, IPR022029): Putative peptidoglycan binding domain
MDFI (PF15316, IPR026134): MyoD family inhibitor
21 CUL5suppressor690.73747.483Cullin (PF00888, IPR001373, SM00182): Cullin family
GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
22 CUL7protein found in more fusions700.584114.450ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
Cullin (PF00888, IPR001373, SM00182): Cullin family
DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918)
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
23 DCUN1D1interactor320.77818.660Cullin_binding (PF03556, IPR005176): Cullin binding
UBA_4 (PF14555): UBA-like domain
24 DYRK2interactor90.9170.180Pkinase (PF00069, IPR000719): Protein kinase domain
25 EEDsuppressor520.62656.206WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
26 EEF1A1suppressor840.589134.022GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
27 EEF1Dprotein found in more fusions210.4845.705EF1_GNE (PF00736, IPR014038, SM00888): EF-1 guanine nucleotide exchange domain
EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
28 EEF1E1suppressor150.8101.732GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain
29 EEF2interactor510.72919.387EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus
EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV
GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
EFG_II (PF14492, IPR009022): Elongation Factor G, domain II
30 EIF4A3interactor510.69324.857DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
31 ESR1suppressor740.66997.809Oest_recep (PF02159, IPR001292): Oestrogen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
32 FANCAoncoprotein60.6001.894Fanconi_A (PF03511, IPR003516): Fanconi anaemia group A protein
Fanconi_A_N (PF15865, IPR031729): Fanconi anaemia group A protein N terminus
33 FANCConcoprotein40.8330.686Fanconi_C (PF02106, IPR000686): Fanconi anaemia group C protein
34 FATE1interactor100Miff (PF05644, IPR008518): Mitochondrial and peroxisomal fission factor Mff
35 FAUinteractor420.78615.927Ribosomal_S30 (PF04758, IPR006846): Ribosomal protein S30
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
36 FBLinteractor580.66536.514Fibrillarin (PF01269, IPR000692): Fibrillarin
37 FBXO6interactor360.55634.022FBA (PF04300, IPR007397): F-box associated region
F-box-like (PF12937, IPR001810): F-box-like
38 FN1oncoprotein920.625179.465fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
39 FUSsuppressor450.56256.188Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
Limkain-b1 (PF11608, IPR024582): Limkain b1
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
40 HIST1H2ADinteractor170.8161.193Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
41 HMOX2interactor30132.174Heme_oxygenase (PF01126, IPR016053): Heme oxygenase
42 HNRNPMinteractor730.61787.976RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNP_M (PF11532, IPR024666): Heterogeneous nuclear ribonucleoprotein M
Collagen_mid (PF15984, IPR031929): Bacterial collagen, middle region
43 HNRNPUprotein found in more fusions1090.626178.686CDC45 (PF02724, IPR003874): CDC45-like protein
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SAP (PF02037, IPR003034, SM00513): SAP domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
AAA_33 (PF13671): AAA domain
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
44 HNRNPUL2interactor120.4554.326CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SAP (PF02037, IPR003034, SM00513): SAP domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
AAA_33 (PF13671): AAA domain
45 HSP90AA5Pinteractor61.0000NA
46 HUWE1oncoprotein600.64963.006BUD22 (PF09073, IPR015158): BUD22
DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908)
DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913)
FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation
HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM)
Mucin (PF01456, IPR000458): Mucin-like glycoprotein
Nop14 (PF04147, IPR007276): Nop14-like family
PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
WWE (PF02825, IPR004170, SM00678): WWE domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)
47 IARSinteractor200.44713.305Anticodon_1 (PF08264, IPR013155): Anticodon-binding domain of tRNA
tRNA-synt_1 (PF00133, IPR002300): tRNA synthetases class I (I, L, M and V)
48 ICAM1oncoprotein500.8567.475Adhes-Ig_like (PF09085, IPR015169): Adhesion molecule, immunoglobulin-like
C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain
ICAM_N (PF03921, IPR013768): Intercellular adhesion molecule (ICAM), N-terminal domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
49 IGSF8oncoprotein540.76630.311V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
50 IL7Rinteractor210.5818.984fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
51 ILF2interactor730.61971.956DZF (PF07528, IPR006561, SM00572): DZF domain
52 ILF3oncoprotein870.639102.385dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
DZF (PF07528, IPR006561, SM00572): DZF domain
53 ITGA4interactor780.638138.303FG-GAP (PF01839, IPR013517): FG-GAP repeat
Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region
Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
54 LOC101929876interactor620.9395.230NA
55 MAGOHinteractor350.7877.807Mago_nashi (PF02792, IPR004023): Mago nashi protein
56 MCM2oncoprotein1020.550292.775AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
57 MRPL12protein found in more fusions150.9230.176Ribosomal_L12 (PF00542, IPR013823): Ribosomal protein L7/L12 C-terminal domain
Ribosomal_L12_N (PF16320, IPR008932): Ribosomal protein L7/L12 dimerisation domain
58 MYBBP1Asuppressor380.7927.428DNA_pol_phi (PF04931, IPR007015): DNA polymerase phi
Pol_alpha_B_N (PF08418, IPR013627): DNA polymerase alpha subunit B N-terminal
59 MYL12Ainteractor50.7000.521EF-hand_11 (PF08976, IPR015070): EF-hand domain
DUF2267 (PF10025, IPR018727): Uncharacterized conserved protein (DUF2267)
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
60 NCLprotein found in more fusions710.556111.701DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
Myc_N (PF01056, IPR012682): Myc amino-terminal region
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
YL1 (PF05764, IPR008895): YL1 nuclear protein
Limkain-b1 (PF11608, IPR024582): Limkain b1
61 NF2suppressor210.7952.411ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
62 NIFKinteractor340.8165.580RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
hNIFK_binding (PF12196, IPR021043): FHA Ki67 binding domain of hNIFK
63 NOP2interactor430.8029.141BSP_II (PF05432, IPR008412): Bone sialoprotein II (BSP-II)
Methyltr_RsmB-F (PF01189, IPR001678): 16S rRNA methyltransferase RsmB/F
P120R (PF08062, IPR012586): P120R (NUC006) repeat
Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
DUF2477 (PF10631, IPR018904): Protein of unknown function (DUF2477)
FAM176 (PF14851): FAM176 family
Methyltr_RsmF_N (PF17125, IPR031341): N-terminal domain of 16S rRNA methyltransferase RsmF
64 NOP56interactor770.74546.757Cytochrom_NNT (PF03264, IPR005126): NapC/NirT cytochrome c family, N-terminal region
Nop (PF01798, IPR002687): snoRNA binding domain, fibrillarin
NOP5NT (PF08156, IPR012974): NOP5NT (NUC127) domain
RNA_polI_A34 (PF08208, IPR013240): DNA-directed RNA polymerase I subunit RPA34.5
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
65 NPM1suppressor1180.543486.770Nucleoplasmin (PF03066): Nucleoplasmin/nucleophosmin domain
SDA1 (PF05285, IPR007949): SDA1
NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain
66 NTRK1oncoprotein690.594101.721I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
67 NUDT21protein found in more fusions210.4746.408NUDIX_2 (PF13869, IPR016706): Nucleotide hydrolase
68 OBSL1interactor510.61156.226BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
69 PA2G4interactor310.61912.691Peptidase_M24 (PF00557, IPR001714): Metallopeptidase family M24
Ribosomal_S25 (PF03297, IPR004977): S25 ribosomal protein
TraC (PF07820, IPR012930): TraC-like protein
70 PABPC1oncoprotein730.56991.597RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain
YflT (PF11181, IPR025889): Heat induced stress protein YflT
71 PABPC4interactor440.54440.141ApbA_C (PF08546, IPR013752): Ketopantoate reductase PanE/ApbA C terminal
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain
HHV-5_US34A (PF17087, IPR031384): Herpesvirus US34A protein family
72 PAN2interactor760.77651.298RNase_T (PF00929, IPR013520): Exonuclease
UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase
WD40_like (PF17005, IPR031544): WD40-like domain
73 PTGES3interactor110.7560.425CS (PF04969, IPR007052): CS domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
74 RBM4Binteractor100.8000.500RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-CCHC (PF00098, IPR001878): Zinc knuckle
75 RHOAsuppressor60.6670.596Ras (PF00071, IPR001806, SM00173): Ras family
76 RPA1suppressor450.59465.954Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain
Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain
77 RPA2oncoprotein400.65124.579RPA_C (PF08784, IPR014892): Replication protein A C terminal
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2
78 RPA3interactor340.72310.808Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3
79 RPL10suppressor990.73875.017Ribosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e
80 RPL10Ainteractor1050.725110.576Ribosomal_L1 (PF00687, IPR028364): Ribosomal protein L1p/L10e family
81 RPL10Linteractor700.85918.896Ribosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e
Cytochrome_P460 (PF16694, IPR032033): Cytochrome P460
82 RPL11suppressor1160.661152.773Ribosomal_L5 (PF00281, IPR002132): Ribosomal protein L5
Ribosomal_L5_C (PF00673, IPR002132): ribosomal L5P family C-terminus
83 RPL12interactor1070.700112.839Ribosomal_L11 (PF00298, IPR020783): Ribosomal protein L11, RNA binding domain
Ribosomal_L11_N (PF03946, IPR020784): Ribosomal protein L11, N-terminal domain
84 RPL13interactor1040.696164.609Ribosomal_L13e (PF01294, IPR001380): Ribosomal protein L13e
85 RPL13Aprotein found in more fusions940.72281.997Ribosomal_L13 (PF00572, IPR005822): Ribosomal protein L13
86 RPL14interactor1170.628223.482KOW (PF00467, IPR005824, SM00739): KOW motif
Ribosomal_L14e (PF01929, IPR002784): Ribosomal protein L14
UPF0688 (PF15772, IPR031530): UPF0688 family
87 RPL15interactor1230.589321.117Ribosomal_L15e (PF00827, IPR000439): Ribosomal L15
88 RPL17interactor910.73791.020Ribosomal_L22 (PF00237, IPR001063): Ribosomal protein L22p/L17e
89 RPL18Ainteractor1000.703106.862Ribosomal_L18A (PF01775, IPR023573): Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A
90 RPL19interactor1110.663157.044DUF1682 (PF07946, IPR012879): Protein of unknown function (DUF1682)
Ribosomal_L19e (PF01280, IPR000196): Ribosomal protein L19e
91 RPL21interactor1090.690138.502Ribosomal_L21e (PF01157, IPR001147): Ribosomal protein L21e
92 RPL22oncoprotein980.76074.294Ribosomal_L22e (PF01776, IPR002671): Ribosomal L22e protein family
93 RPL23interactor1060.711102.744Ribosomal_L14 (PF00238, IPR000218): Ribosomal protein L14p/L23e
94 RPL23Ainteractor1130.670154.638Ribosomal_L23 (PF00276, IPR013025): Ribosomal protein L23
Ribosomal_L23eN (PF03939, IPR005633): Ribosomal protein L23, N-terminal domain
95 RPL24protein found in more fusions1080.691136.885MAS20 (PF02064, IPR002056): MAS20 protein import receptor
Ribosomal_L24e (PF01246, IPR000988): Ribosomal protein L24e
96 RPL26oncoprotein600.79424.057TP2 (PF01254, IPR000678): Nuclear transition protein 2
Ribosomal_L26 (PF16906, IPR005756): Ribosomal proteins L26 eukaryotic, L24P archaeal
97 RPL26L1interactor520.77324.737Ribosomal_L26 (PF16906, IPR005756): Ribosomal proteins L26 eukaryotic, L24P archaeal
98 RPL27protein found in more fusions950.77355.190Ribosomal_L27e (PF01777, IPR001141): Ribosomal L27e protein family
99 RPL27Ainteractor970.73478.399Ribosomal_L27A (PF00828, IPR021131): Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
100 RPL3protein found in more fusions1050.709113.170Ribosomal_L3 (PF00297, IPR000597): Ribosomal protein L3
101 RPL30interactor970.73190.143NCBP3 (PF10309, IPR019416): Nuclear cap-binding protein subunit 3
102 RPL31interactor1000.73579.629Ribosomal_L31e (PF01198, IPR000054): Ribosomal protein L31e
103 RPL32interactor580.9017.239Ribosomal_L32e (PF01655, IPR001515): Ribosomal protein L32
104 RPL34interactor640.88311.636Redoxin (PF08534, IPR013740): Redoxin
Ribosomal_L34e (PF01199, IPR008195): Ribosomal protein L34e
105 RPL35interactor860.81340.291Ribosomal_L29 (PF00831, IPR001854): Ribosomal L29 protein
XFP_N (PF09364, IPR018970): XFP N-terminal domain
106 RPL35Ainteractor680.87128.565Ribosomal_L35Ae (PF01247, IPR001780): Ribosomal protein L35Ae
107 RPL36interactor870.81838.947Ribosomal_L36e (PF01158, IPR000509): Ribosomal protein L36e
108 RPL37Aprotein found in more fusions930.75970.864Ribosomal_L37ae (PF01780, IPR002674): Ribosomal L37ae protein family
109 RPL38protein found in more fusions790.85930.357Ribosomal_L38e (PF01781, IPR002675): Ribosomal L38e protein family
110 RPL3Linteractor350.9561.865Ribosomal_L3 (PF00297, IPR000597): Ribosomal protein L3
111 RPL4interactor1250.595303.469Ribosomal_L4 (PF00573, IPR002136): Ribosomal protein L4/L1 family
Ribos_L4_asso_C (PF14374, IPR025755): 60S ribosomal protein L4 C-terminal domain
112 RPL5suppressor1220.630254.809Ribosomal_L18_c (PF14204, IPR025607): Ribosomal L18 C-terminal region
Ribosomal_L5e (PF17144): Ribosomal large subunit proteins 60S L5, and 50S L18
113 RPL6protein found in more fusions1260.604229.678Ribosomal_L6e (PF01159, IPR000915): Ribosomal protein L6e
Ribosomal_L6e_N (PF03868, IPR005568): Ribosomal protein L6, N-terminal domain
114 RPL7interactor1200.616274.332Ribosomal_L30 (PF00327, IPR016082): Ribosomal protein L30p/L7e
Ribosomal_L30_N (PF08079, IPR012988): Ribosomal L30 N-terminal domain
115 RPL7Aprotein found in more fusions1140.643188.337Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
116 RPL8interactor1120.649158.742Ribosomal_L2 (PF00181, IPR022666): Ribosomal Proteins L2, RNA binding domain
Ribosomal_L2_C (PF03947, IPR022669): Ribosomal Proteins L2, C-terminal domain
117 RPL9interactor1080.696136.773Ribosomal_L6 (PF00347, IPR020040): Ribosomal protein L6
118 RPLP0protein found in more fusions1160.637230.806Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
Ribosomal_L10 (PF00466, IPR001790): Ribosomal protein L10
119 RPLP0P6protein found in more fusions710.80443.867NA
120 RPLP1interactor770.80454.140Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
121 RPLP2protein found in more fusions930.75271.707Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
122 RPS10interactor910.79554.258S10_plectin (PF03501, IPR005326): Plectin/S10 domain
123 RPS10P5interactor210.9620.386DUF11 (PF01345, IPR001434): Domain of unknown function DUF11
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase (PF00069, IPR000719): Protein kinase domain
PPAK (PF02818, IPR004168): PPAK motif
Titin_Z (PF09042, IPR015129): Titin Z
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Y_Y_Y (PF07495, IPR011123): Y_Y_Y domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
Ig_3 (PF13927): Immunoglobulin domain
124 RPS11interactor1020.720125.050Ribosomal_S17 (PF00366, IPR000266): Ribosomal protein S17
Ribosomal_S17_N (PF16205, IPR032440): Ribosomal_S17 N-terminal
125 RPS12interactor800.85728.401Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
126 RPS13interactor1090.704102.022Ribosomal_S13_N (PF08069, IPR012606): Ribosomal S13/S15 N-terminal domain
Ribosomal_S15 (PF00312, IPR000589): Ribosomal protein S15
127 RPS14protein found in more fusions1060.703156.685Ribosomal_S11 (PF00411, IPR001971): Ribosomal protein S11
128 RPS15interactor730.87813.051Ribosomal_S19 (PF00203, IPR002222): Ribosomal protein S19
Prok_Ub (PF14454, IPR032866): Prokaryotic Ubiquitin
129 RPS15Ainteractor1070.697125.096Ribosomal_S8 (PF00410, IPR000630): Ribosomal protein S8
130 RPS16interactor1160.654237.975Ribosomal_S9 (PF00380, IPR000754): Ribosomal protein S9/S16
131 RPS17interactor660.82815.670Ribosomal_S17e (PF00833, IPR001210): Ribosomal S17
132 RPS18interactor950.77947.228Ribosomal_S13 (PF00416, IPR001892): Ribosomal protein S13/S18
133 RPS19protein found in more fusions980.76366.580Ribosomal_S19e (PF01090, IPR001266): Ribosomal protein S19e
134 RPS2interactor1240.608269.522Ribosomal_S5 (PF00333, IPR013810): Ribosomal protein S5, N-terminal domain
Ribosomal_S5_C (PF03719, IPR005324): Ribosomal protein S5, C-terminal domain
135 RPS20interactor920.78556.781Ribosomal_S10 (PF00338, IPR027486): Ribosomal protein S10p/S20e
136 RPS21interactor730.86813.923Ribosomal_S21e (PF01249, IPR001931): Ribosomal protein S21e
137 RPS23protein found in more fusions1030.703106.720Ribosom_S12_S23 (PF00164, IPR006032): Ribosomal protein S12/S23
138 RPS24protein found in more fusions1010.70696.939Fascin (PF06268, IPR022768): Fascin domain
Ribosomal_S24e (PF01282, IPR001976): Ribosomal protein S24e
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
139 RPS25interactor1020.74378.628Ribosomal_S25 (PF03297, IPR004977): S25 ribosomal protein
140 RPS26interactor880.78448.167Ribosomal_S26e (PF01283, IPR000892): Ribosomal protein S26e
141 RPS27protein found in more fusions770.87416.685Ribosomal_S27e (PF01667, IPR000592): Ribosomal protein S27
DUF3795 (PF12675, IPR024227): Protein of unknown function (DUF3795)
142 RPS27Ainteractor560.80555.626DUF1049 (PF06305, IPR010445): Protein of unknown function (DUF1049)
143 RPS27Linteractor520.87813.640E7 (PF00527, IPR000148): E7 protein, Early protein
Ribosomal_S27e (PF01667, IPR000592): Ribosomal protein S27
zf-C2HC5 (PF06221, IPR009349): Putative zinc finger motif, C2HC5-type
DUF3382 (PF11862, IPR021807): Domain of unknown function (DUF3382)
144 RPS28interactor720.82019.697Ribosomal_S28e (PF01200, IPR000289): Ribosomal protein S28e
145 RPS3interactor1210.617245.578KH_2 (PF07650, IPR004044): KH domain
Ribosomal_S3_C (PF00189, IPR001351): Ribosomal protein S3, C-terminal domain
146 RPS3Ainteractor1200.625760.426Ribosomal_S3Ae (PF01015, IPR001593): Ribosomal S3Ae family
147 RPS4Xinteractor1240.616242.081KOW (PF00467, IPR005824, SM00739): KOW motif
Ribosomal_S4e (PF00900, IPR013845): Ribosomal family S4e
RS4NT (PF08071, IPR013843): RS4NT (NUC023) domain
S4 (PF01479, IPR002942, SM00363): S4 domain
40S_S4_C (PF16121, IPR032277): 40S ribosomal protein S4 C-terminus
148 RPS5interactor990.73479.129Ribosomal_S7 (PF00177, IPR023798): Ribosomal protein S7p/S5e
149 RPS6protein found in more fusions1210.637170.226Ribosomal_S6e (PF01092, IPR001377): Ribosomal protein S6e
DUF4574 (PF15141, IPR027896): Domain of unknown function (DUF4574)
150 RPS7interactor980.72880.954Ribosomal_S7e (PF01251, IPR000554): Ribosomal protein S7e
151 RPS8interactor1280.609246.633Ribosomal_S8e (PF01201, IPR022309): Ribosomal protein S8e
152 RPS9interactor1100.655164.817Ribosomal_S4 (PF00163, IPR001912): Ribosomal protein S4/S9 N-terminal domain
S4 (PF01479, IPR002942, SM00363): S4 domain
153 RPSAinteractor980.74086.808Ribosomal_S2 (PF00318, IPR001865): Ribosomal protein S2
40S_SA_C (PF16122, IPR032281): 40S ribosomal protein SA C-terminus
154 SFNsuppressor400.8117.60114-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
155 SKIoncoprotein200.5618.424c-SKI_SMAD_bind (PF08782, IPR014890, SM01046): c-SKI Smad4 binding domain
Ski_Sno (PF02437, IPR003380): SKI/SNO/DAC family
SlyX (PF04102, IPR007236): SlyX
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
156 SLC25A5interactor630.62292.569Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
157 SNU13interactor480.8219.886Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
158 STAU1protein found in more fusions530.67449.544dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
Staufen_C (PF16482, IPR032478): Staufen C-terminal domain
159 TP53suppressor780.66481.798DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
160 TUBA1Binteractor170.2798.927Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
161 U2AF2protein found in more fusions370.59736.970RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Transformer (PF06495, IPR010519): Fruit fly transformer protein
162 UBL4Ainteractor820.71282.607ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
163 VCAM1interactor770.660103.552C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
164 XPO1interactor490.71926.966CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
165 ZBTB1interactor270.8525.757BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
zf-BED (PF02892, IPR003656, SM00614): BED zinc finger
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger

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