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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)11
The number (and %) of the onco-proteins2 (18.18 %)
The number (and %) of the tumor suppressors1 (9.09 %)
Total number of binary PPIs (saturation %)14 (25.45 %)
The number (and %) of affected PPIs9 (64.29 %)
The number of possible different fusions2
PPI diameter2
PPI radiusinf
The average degree of PPI2.182
Assortativity coefficient-0.2416
The network average Clustering coefficient0.432
The number (and %) of a zero Clustering coefficients5 (45.45 %)
The number (and %) of a zero Betweenness Centrality9 (81.82 %)


List of the fusions

PPI for parental proteins: FHAD1,SMAP1 All fusions
Proteins found in more fusions APP (see 5 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Domains (Pfam, InterPro, SMART): description
1 FHAD1interactor000DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641)
FHA (PF00498, IPR000253, SM00240): FHA domain
IncA (PF04156, IPR007285): IncA protein
LPP (PF04728, IPR006817): Lipoprotein leucine-zipper
Phage_int_SAM_1 (PF02899, IPR004107): Phage integrase, N-terminal SAM-like domain
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
SlyX (PF04102, IPR007236): SlyX
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
TBPIP (PF07106, IPR010776): Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
XhlA (PF10779, IPR019715): Haemolysin XhlA
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
2 SMAP1parental protein90.08365.000ArfGap (PF01412, IPR001164, SM00105): Putative GTPase activating protein for Arf
DUF106 (PF01956, IPR002809): Integral membrane protein DUF106
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
3 APPprotein found in more fusions31.0000APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
4 BRF2interactor100A2L_zn_ribbon (PF08792, IPR014900): A2L zinc ribbon domain
TFIIB (PF00382, IPR013150): Transcription factor TFIIB repeat
TF_Zn_Ribbon (PF08271, IPR013137): TFIIB zinc-binding
5 HSPA1Linteractor21.0000HSP70 (PF00012, IPR013126): Hsp70 protein
6 KLHL18interactor100BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
7 MICU2interactor10023S_rRNA_IVP (PF05635, IPR012657): 23S rRNA-intervening sequence protein
EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
8 PHLDA3suppressor21.0000PH (PF00169, IPR001849, SM00233): PH domain
9 PTP4A3oncoprotein100DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
10 WRAP73interactor31.0000eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
IKI3 (PF04762, IPR006849): IKI3 family
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
DUF2555 (PF10742, IPR019678): Protein of unknown function (DUF2555)
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
11 XPO1interactor30.6671.000CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region

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