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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins PAPPA2, LOC107986521 (from a repository: Fri Nov 30 02:30:42 2018)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)5
The number (and %) of the onco-proteins0 (0.00 %)
The number (and %) of the tumor suppressors2 (40.00 %)
Total number of binary PPIs (saturation %)4 (40.00 %)
The number (and %) of affected PPIs3 (75.00 %)
The number of possible different fusions2
PPI diameter2
PPI radiusinf
The average degree of PPI1.200
Assortativity coefficient0
The network average Clustering coefficient0.000
The number (and %) of a zero Clustering coefficients5 (100.00 %)
The number (and %) of a zero Betweenness Centrality4 (80.00 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: LOC107986521,PAPPA2 All fusions
Proteins found in more fusions SMAD4 (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 LOC107986521interactor000NA
2 PAPPA2parental protein306.000Peptidase_M43 (PF05572, IPR008754): Pregnancy-associated plasma protein-A
Sushi (PF00084, IPR000436, SM00032): Sushi repeat (SCR repeat)
Notch (PF00066, IPR000800, SM00004): LNR domain
Laminin_G_3 (PF13385): Concanavalin A-like lectin/glucanases superfamily
DUF4215 (PF13948, IPR011936): Domain of unknown function (DUF4215)
3 IGFBP3suppressor100IGFBP (PF00219, IPR000867, SM00121): Insulin-like growth factor binding protein
Thyroglobulin_1 (PF00086, IPR000716, SM00211): Thyroglobulin type-1 repeat
4 SMAD4suppressor200MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
5 ZNF512Binteractor100YTV (PF07639, IPR011521): YTV
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-C2HC5 (PF06221, IPR009349): Putative zinc finger motif, C2HC5-type
zf-Nse (PF11789, IPR004181): Zinc-finger of the MIZ type in Nse subunit
Zn_Tnp_IS1595 (PF12760, IPR024442): Transposase zinc-ribbon domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-C2H2_aberr (PF17017, IPR031514): Aberrant zinc-finger

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