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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)109
The number (and %) of the onco-proteins32 (29.36 %)
The number (and %) of the tumor suppressors11 (10.09 %)
Total number of binary PPIs (saturation %)597 (10.14 %)
The number (and %) of affected PPIs108 (18.09 %)
The number of possible different fusions17
PPI diameter5
PPI radius3
The average degree of PPI10.110
Assortativity coefficient-0.2111
The network average Clustering coefficient0.557
The number (and %) of a zero Clustering coefficients7 (6.42 %)
The number (and %) of a zero Betweenness Centrality26 (23.85 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: MYD88,MRPS35 All fusions
Proteins found in more fusions TRAF6 (see 1 fusions); NDUFAF8 (see 1 fusions); SYK (see 1 fusions); PFKL (see 2 fusions); CUL3 (see 1 fusions); SQSTM1 (see 5 fusions); SIAH1 (see 4 fusions); RAC1 (see 1 fusions); ATP6V1C1 (see 3 fusions); PRDX1 (see 1 fusions); SIAH2 (see 1 fusions); MAP3K7 (see 7 fusions); UBC (see 4 fusions); COQ4 (see 1 fusions); CBLB (see 4 fusions); SMAD3 (see 3 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 MYD88parental protein570.0843147.199Death (PF00531, IPR000488, SM00005): Death domain
TIR (PF01582, IPR000157, SM00255): TIR domain
2 MRPS35parental protein510.1962385.766MRP-S28 (PF10213, IPR019349): Mitochondrial ribosomal subunit protein
3 ABCC2interactor21.0000ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region
ABC_tran (PF00005, IPR003439): ABC transporter
DUF805 (PF05656, IPR008523): Protein of unknown function (DUF805)
DUF87 (PF01935, IPR002789): Domain of unknown function DUF87
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
4 ATP1B1interactor21.0000Na_K-ATPase (PF00287, IPR000402): Sodium / potassium ATPase beta chain
5 ATP6V1C1protein found in more fusions200V-ATPase_C (PF03223, IPR004907): V-ATPase subunit C
6 AURKAoncoprotein110.40076.313Pkinase (PF00069, IPR000719): Protein kinase domain
MTBP_C (PF14920, IPR029418): MDM2-binding
7 BST2oncoprotein30.3339.823DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472)
BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
8 BTKsuppressor90.464166.121BTK (PF00779, IPR001562, SM00107): BTK motif
PH (PF00169, IPR001849, SM00233): PH domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
9 BTRConcoprotein160.305396.879WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
10 CAND1interactor220.495110.262Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981)
HEAT (PF02985, IPR000357): HEAT repeat
TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20)
RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
11 CBLBoncoprotein80.47645.522Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1
Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain
Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
PRIMA1 (PF16101): Proline-rich membrane anchor 1
12 CD93interactor100EGF (PF00008, IPR000742, SM00181): EGF-like domain
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
Plasmod_Pvs28 (PF06247, IPR010423): Pvs28 EGF domain
Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site
TMEM154 (PF15102, IPR028064): TMEM154 protein family
13 CEP250interactor100.7114.650ACCA (PF03255, IPR001095): Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
DASH_Dam1 (PF08653, IPR013962): DASH complex subunit Dam1
DivIC (PF04977, IPR007060): Septum formation initiator
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
EHN (PF06441, IPR010497): Epoxide hydrolase N terminus
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
IncA (PF04156, IPR007285): IncA protein
Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain
SlyX (PF04102, IPR007236): SlyX
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
Endonuc_Holl (PF10107, IPR019287): Endonuclease related to archaeal Holliday junction resolvase
DUF2570 (PF10828, IPR022538): Protein of unknown function (DUF2570)
DGF-1_C (PF11040, IPR021053): Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus
DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968)
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472)
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
KAsynt_C_assoc (PF16197, IPR032821): Ketoacyl-synthetase C-terminal extension
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
14 CISHinteractor203.804SH2 (PF00017, IPR000980, SM00252): SH2 domain
ER-remodelling (PF14755, IPR032786): Intracellular membrane remodeller
SOCS_box (PF07525, IPR001496): SOCS box
15 COQ4protein found in more fusions31.0000Coq4 (PF05019, IPR007715): Coenzyme Q (ubiquinone) biosynthesis protein Coq4
16 COQ5interactor31.0000Ubie_methyltran (PF01209, IPR004033): ubiE/COQ5 methyltransferase family
17 CUL3protein found in more fusions290.312961.030Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
18 CYLDsuppressor80.64313.343CAP_GLY (PF01302, IPR000938, SM01052): CAP-Gly domain
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
zf-HIT (PF04438, IPR007529): HIT zinc finger
CYLD_phos_site (PF16607): Phosphorylation region of CYLD, unstructured
19 DAP3interactor230.511188.753DAP3 (PF10236, IPR019368): Mitochondrial ribosomal death-associated protein 3
20 EIF3Concoprotein41.0000eIF-3c_N (PF05470, IPR008905): Eukaryotic translation initiation factor 3 subunit 8 N-terminus
PCI (PF01399, IPR000717, SM00088): PCI domain
21 EPHA2suppressor31.0000fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain
Ephrin_lbd (PF01404, IPR001090, SM00615): Ephrin receptor ligand binding domain
EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain
22 FADDsuppressor60.267107.009Death (PF00531, IPR000488, SM00005): Death domain
DED (PF01335, IPR001875, SM00031): Death effector domain
Hpt (PF01627, IPR008207, SM00073): Hpt domain
23 FLIIoncoprotein40.50071.130Gelsolin (PF00626, IPR007123): Gelsolin repeat
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
24 HAUS2interactor50.6001.335DpnII (PF04556, IPR007637): DpnII restriction endonuclease
HAUS2 (PF15003, IPR028346): HAUS augmin-like complex subunit 2
25 HDAC6oncoprotein100.36173.317Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
PSGP (PF07276, IPR009900): Apopolysialoglycoprotein (PSGP)
zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
26 HNRNPA1interactor230.528126.554RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
27 HNRNPUinteractor250.317441.988CDC45 (PF02724, IPR003874): CDC45-like protein
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SAP (PF02037, IPR003034, SM00513): SAP domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
AAA_33 (PF13671): AAA domain
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
28 IKBKEinteractor80.52451.213IncA (PF04156, IPR007285): IncA protein
Pkinase (PF00069, IPR000719): Protein kinase domain
SlyX (PF04102, IPR007236): SlyX
zf-RING_9 (PF13901, IPR025258): Putative zinc-RING and/or ribbon
29 IKBKGinteractor170.342176.064CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
DUF725 (PF05267, IPR007931): Protein of unknown function (DUF725)
NEMO (PF11577, IPR021063): NF-kappa-B essential modulator NEMO
LLC1 (PF14945, IPR020339): Normal lung function maintenance, Low in Lung Cancer 1 protein
CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
30 IL1R1interactor70.8102.489TIR (PF01582, IPR000157, SM00255): TIR domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
31 IL1RAPinteractor50.6003.333ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
TIR (PF01582, IPR000157, SM00255): TIR domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
32 IL1RL1interactor41.0000I-set (PF07679, IPR013098): Immunoglobulin I-set domain
TIR (PF01582, IPR000157, SM00255): TIR domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
33 ILF3oncoprotein120.59141.849dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
DZF (PF07528, IPR006561, SM00572): DZF domain
34 IRAK1interactor250.243718.073Death (PF00531, IPR000488, SM00005): Death domain
Pkinase (PF00069, IPR000719): Protein kinase domain
35 IRAK2oncoprotein100.6229.211Death (PF00531, IPR000488, SM00005): Death domain
Pkinase (PF00069, IPR000719): Protein kinase domain
36 IRAK3interactor51.0000Death (PF00531, IPR000488, SM00005): Death domain
Pkinase (PF00069, IPR000719): Protein kinase domain
37 IRAK4interactor130.50021.607Death (PF00531, IPR000488, SM00005): Death domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
38 IRF4suppressor31.0000IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor
IRF-3 (PF10401, IPR019471): Interferon-regulatory factor 3
39 IRF5suppressor31.0000IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor
IRF-3 (PF10401, IPR019471): Interferon-regulatory factor 3
40 IRF7interactor60.5002.619IRF (PF00605, IPR001346, SM00348): Interferon regulatory factor transcription factor
IRF-3 (PF10401, IPR019471): Interferon-regulatory factor 3
41 LAMTOR3interactor30.6670.667MAPKK1_Int (PF08923, IPR015019): Mitogen-activated protein kinase kinase 1 interacting
42 LRPPRCinteractor100.31193.669DED (PF01335, IPR001875, SM00031): Death effector domain
MA3 (PF02847, IPR003891, SM00544): MA3 domain
PPR (PF01535, IPR002885): PPR repeat
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
ApoB100_C (PF12491, IPR022176): Apolipoprotein B100 C terminal
PPR_2 (PF13041, IPR002885): PPR repeat family
PPR_3 (PF13812, IPR002885): Pentatricopeptide repeat domain
TPR_19 (PF14559): Tetratricopeptide repeat
PPR_long (PF17177): Pentacotripeptide-repeat region of PROPR
43 LRRFIP1oncoprotein30.6679.809CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
Rxt3 (PF08642, IPR013951): Histone deacetylation protein Rxt3
LRRFIP (PF09738, IPR019139): LRRFIP family
RP-C_C (PF11800, IPR021760): Replication protein C C-terminal region
Coilin_N (PF15862, IPR031722): Coilin N-terminus
44 LRRFIP2interactor21.0000TACC (PF05010, IPR007707): Transforming acidic coiled-coil-containing protein (TACC)
LRRFIP (PF09738, IPR019139): LRRFIP family
45 MALsuppressor21.0000MARVEL (PF01284, IPR008253): Membrane-associating domain
46 MAP3K7oncoprotein140.34638.102Mnd1 (PF03962, IPR005647): Mnd1 family
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
47 MBIPinteractor31.0000DUF1192 (PF06698, IPR009579): Protein of unknown function (DUF1192)
48 MDM2oncoprotein100.361212.081Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region
Presenilin (PF01080, IPR001108): Presenilin
SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain
zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
49 MRPL42interactor70.7621.705MRP-S32 (PF10210, IPR019346): Mitochondrial 28S ribosomal protein S32
50 MRPL50interactor70.7628.663Ribosomal_L50 (PF10501, IPR018305): Ribosomal subunit 39S
51 MRPL58interactor190.53836.192RF-1 (PF00472, IPR000352): RF-1 domain
52 MRPS18Binteractor170.68436.314Ribosomal_S18 (PF01084, IPR001648): Ribosomal protein S18
HTH_21 (PF13276, IPR025948): HTH-like domain
zf-RING_10 (PF16685, IPR032043): zinc RING finger of MSL2
53 MRPS2interactor190.70824.591Ribosomal_S2 (PF00318, IPR001865): Ribosomal protein S2
54 MRPS22interactor280.429486.975MRP-S22 (PF10245, IPR019374): Mitochondrial 28S ribosomal protein S22
55 MRPS23interactor160.70849.402MRP-S23 (PF10484, IPR023611): Mitochondrial ribosomal protein S23
56 MRPS25interactor140.6489.576L51_S25_CI-B8 (PF05047, IPR007741, SM00916): Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain
57 MRPS26interactor170.46370.963MRP-S26 (PF14943, IPR026140): Mitochondrial ribosome subunit S26
58 MRPS31interactor230.542134.169MRP-S31 (PF15433, IPR026299): Mitochondrial 28S ribosomal protein S31
59 MRPS5interactor230.553117.278Ribosomal_S5 (PF00333, IPR013810): Ribosomal protein S5, N-terminal domain
Ribosomal_S5_C (PF03719, IPR005324): Ribosomal protein S5, C-terminal domain
60 MRPS7interactor140.70332.714DUF454 (PF04304, IPR007401): Protein of unknown function (DUF454)
Ribosomal_S7 (PF00177, IPR023798): Ribosomal protein S7p/S5e
61 MRPS9interactor280.489168.779Ribosomal_S9 (PF00380, IPR000754): Ribosomal protein S9/S16
62 NANOGinteractor90.25076.926Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
63 NDUFAF8protein found in more fusions31.0000ZU5 (PF00791, IPR000906, SM00218): ZU5 domain
64 NOL12interactor70.8570.487DUF2357 (PF09823, IPR018633): Domain of unknown function (DUF2357)
Nop25 (PF09805, IPR019186): Nucleolar protein 12 (25kDa)
65 NTRK1oncoprotein330.2261517.887I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
66 PELI1interactor80.60739.135Pellino (PF04710, IPR006800): Pellino
67 PFKLprotein found in more fusions40.6679.809PFK (PF00365, IPR000023): Phosphofructokinase
68 PHF8interactor21.0000JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase
PHD (PF00628, IPR019787, SM00249): PHD-finger
TSGP1 (PF07771, IPR011694): Tick salivary peptide group 1
AC_N (PF16214, IPR032628): Adenylyl cyclase N-terminal extracellular and transmembrane region
69 POLR1Cinteractor50.400106.332RNA_pol_A_bac (PF01000, IPR011262): RNA polymerase Rpb3/RpoA insert domain
70 POU5F1oncoprotein80.33347.450Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
71 PRDX1oncoprotein80.429103.012AhpC-TSA (PF00578, IPR000866): AhpC/TSA family
1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin
72 PTCD3interactor220.532118.146PPR (PF01535, IPR002885): PPR repeat
PPR_2 (PF13041, IPR002885): PPR repeat family
PPR_3 (PF13812, IPR002885): Pentatricopeptide repeat domain
73 RAC1oncoprotein40.33320.431Ras (PF00071, IPR001806, SM00173): Ras family
74 RAP1Boncoprotein100Ras (PF00071, IPR001806, SM00173): Ras family
75 RPLP1interactor51.0000Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
76 SARM1interactor50.70029.148Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Carb_kinase (PF01256, IPR000631): Carbohydrate kinase
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
HEAT_2 (PF13646): HEAT repeats
TIR_2 (PF13676, IPR000157): TIR domain
77 SASH1suppressor50.9000.333PGA2 (PF07543, IPR011431): Protein trafficking PGA2
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
SH3_2 (PF07653, IPR011511): Variant SH3 domain
Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
SLY (PF12485, IPR021090): Lymphocyte signaling adaptor protein
78 SIAH1suppressor40.6674.193Sina (PF03145, IPR018121): Seven in absentia protein family
79 SIAH2oncoprotein31.0000Sina (PF03145, IPR018121): Seven in absentia protein family
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
80 SLC1A5interactor41.0000SDF (PF00375, IPR001991): Sodium:dicarboxylate symporter family
81 SMAD3oncoprotein90.25039.470MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
82 SMAD6interactor40.5003.558MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
83 SMURF1interactor140.256445.749C2 (PF00168, IPR000008, SM00239): C2 domain
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
84 SOX2oncoprotein90.50025.600HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
SOXp (PF12336, IPR022097): SOX transcription factor
85 SPOPsuppressor60.30046.008BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
MATH (PF00917, IPR002083, SM00061): MATH domain
86 SQSTM1oncoprotein110.48955.904PB1 (PF00564, IPR000270, SM00666): PB1 domain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
UBA_5 (PF16577, IPR015940): UBA domain
87 STAP2interactor100SH2 (PF00017, IPR000980, SM00252): SH2 domain
88 SYKsuppressor110.51114.182Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
89 TIRAPinteractor110.53315.157TIR_2 (PF13676, IPR000157): TIR domain
90 TLR2interactor41.0000LRRCT (PF01463, IPR000483, SM00082): Leucine rich repeat C-terminal domain
TIR (PF01582, IPR000157, SM00255): TIR domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
91 TLR3interactor60.7332.248LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
LRRCT (PF01463, IPR000483, SM00082): Leucine rich repeat C-terminal domain
LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain
TIR (PF01582, IPR000157, SM00255): TIR domain
LRR_5 (PF13306, IPR026906): Leucine rich repeats (6 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
92 TLR4interactor90.5289.297LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
TIR (PF01582, IPR000157, SM00255): TIR domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
LRR_9 (PF14580): Leucine-rich repeat
93 TLR5interactor100LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
LRRCT (PF01463, IPR000483, SM00082): Leucine rich repeat C-terminal domain
TIR (PF01582, IPR000157, SM00255): TIR domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
LRR_8 (PF13855, IPR001611): Leucine rich repeat
94 TLR7interactor100LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain
TIR (PF01582, IPR000157, SM00255): TIR domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
LRR_8 (PF13855, IPR001611): Leucine rich repeat
95 TLR9interactor60.6671.773LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
TIR (PF01582, IPR000157, SM00255): TIR domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
LRR_8 (PF13855, IPR001611): Leucine rich repeat
96 TNFRSF13Boncoprotein50.7001.015TACI-CRD2 (PF09305, IPR015384): TACI, cysteine-rich domain
97 TNIP1interactor60.8005.692ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724)
Filament (PF00038, IPR001664): Intermediate filament protein
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
DUF4201 (PF13870, IPR025254): Domain of unknown function (DUF4201)
FlxA (PF14282, IPR025577): FlxA-like protein
CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
98 TRA2Ainteractor170.65430.604DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RSRP (PF17069): Arginine/Serine-Rich protein 1
99 TRAF3oncoprotein140.29566.292ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
S-AdoMet_synt_M (PF02772, IPR022629): S-adenosylmethionine synthetase, central domain
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
MPS2 (PF17060, IPR031433): Monopolar spindle protein 2
Spc29 (PF17082, IPR031392): Spindle Pole Component 29
100 TRAF6protein found in more fusions290.220842.053SlyX (PF04102, IPR007236): SlyX
zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
101 TRMT10Binteractor130.7823.190tRNA_m1G_MT (PF01746, IPR016009): tRNA (Guanine-1)-methyltransferase
102 TRUB2interactor90.46411.061TruB_N (PF01509, IPR002501): TruB family pseudouridylate synthase (N terminal domain)
TruB_C_2 (PF16198, IPR032819): tRNA pseudouridylate synthase B C-terminal domain
103 TXNoncoprotein60.200140.894Thioredoxin (PF00085, IPR013766): Thioredoxin
104 UBCprotein found in more fusions270.2281055.079ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
105 UQCRFS1P1interactor40.33343.866NA
106 USP42interactor60.40015.080TFIIF_alpha (PF05793, IPR008851): Transcription initiation factor IIF, alpha subunit (TFIIF-alpha)
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19
AP3D1 (PF06375): AP-3 complex subunit delta-1
107 USP7oncoprotein160.190492.342MATH (PF00917, IPR002083, SM00061): MATH domain
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
USP7_ICP0_bdg (PF12436, IPR024729): ICP0-binding domain of Ubiquitin-specific protease 7
USP7_C2 (PF14533, IPR029346): Ubiquitin-specific protease C-terminal
108 ZBTB38interactor31.0000BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-met (PF12874): Zinc-finger of C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-C2H2_7 (PF15269): Zinc-finger
zf-C2H2_8 (PF15909, IPR031799): C2H2-type zinc ribbon
109 ZC3H3interactor110.7095.691zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
CCDC24 (PF15669, IPR031367): Coiled-coil domain-containing protein 24 family

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