1 |
ACTB | parental protein | 223 | 0.076 | 28937.125 | Actin (PF00022, IPR004000, SM00268): Actin |
2 |
A2M | protein found in more fusions | 14 | 0.218 | 35.317 | A2M (PF00207, IPR001599): Alpha-2-macroglobulin family A2M_comp (PF07678, IPR011626): A-macroglobulin complement component A2M_N (PF01835, IPR002890): MG2 domain A2M_N_2 (PF07703, IPR011625): Alpha-2-macroglobulin family N-terminal region A2M_recep (PF07677, IPR009048): A-macroglobulin receptor MP (PF01107, IPR028919): Viral movement protein (MP) SVA (PF05326, IPR007990): Seminal vesicle autoantigen (SVA) Thiol-ester_cl (PF10569, IPR019565): Alpha-macro-globulin thiol-ester bond-forming region |
3 |
ABLIM1 | interactor | 9 | 1.000 | 0 | LIM (PF00412, IPR001781, SM00132): LIM domain VHP (PF02209, IPR003128, SM00153): Villin headpiece domain zf-dskA_traR (PF01258, IPR000962): Prokaryotic dksA/traR C4-type zinc finger DUF2175 (PF09943, IPR018686): Uncharacterized protein conserved in archaea (DUF2175) AbLIM_anchor (PF16182, IPR032402): Putative adherens-junction anchoring region of AbLIM |
4 |
ACD | interactor | 5 | 0.600 | 3.400 | TPP1 (PF10341, IPR019437): Shelterin complex subunit, TPP1/ACD |
5 |
ACE | interactor | 2 | 1.000 | 0 | Peptidase_M2 (PF01401, IPR001548): Angiotensin-converting enzyme |
6 |
ACTG1 | protein found in more fusions | 53 | 0.198 | 659.982 | Actin (PF00022, IPR004000, SM00268): Actin |
7 |
ACTR2 | interactor | 27 | 0.467 | 53.810 | Actin (PF00022, IPR004000, SM00268): Actin |
8 |
ACTR3 | interactor | 17 | 0.559 | 22.639 | Actin (PF00022, IPR004000, SM00268): Actin |
9 |
ADA | interactor | 3 | 0.667 | 1.000 | A_deaminase (PF00962, IPR001365): Adenosine/AMP deaminase |
10 |
AGO4 | interactor | 4 | 0.500 | 0.693 | ArgoL1 (PF08699, IPR014811, SM01163): Argonaute linker 1 domain PAZ (PF02170, IPR003100, SM00949): PAZ domain Piwi (PF02171, IPR003165, SM00950): Piwi domain ArgoN (PF16486, IPR032474): N-terminal domain of argonaute ArgoMid (PF16487, IPR032473): Mid domain of argonaute ArgoL2 (PF16488, IPR032472): Argonaute linker 2 domain |
11 |
AIMP2 | suppressor | 8 | 0.619 | 2.114 | GST_C_2 (PF13410): Glutathione S-transferase, C-terminal domain GST_C_3 (PF14497, IPR004046): Glutathione S-transferase, C-terminal domain AIMP2_LysRS_bd (PF16780, IPR031889): AIMP2 lysyl-tRNA synthetase binding domain |
12 |
AKT1 | oncoprotein | 26 | 0.267 | 117.606 | PH (PF00169, IPR001849, SM00233): PH domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
13 |
ALK | oncoprotein | 7 | 0.619 | 3.870 | MAM (PF00629, IPR000998, SM00137): MAM domain, meprin/A5/mu Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Ldl_recept_a (PF00057, IPR002172, SM00192): Low-density lipoprotein receptor domain class A Gly_rich (PF12810): Glycine rich protein FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site |
14 |
AMOT | oncoprotein | 8 | 0.381 | 5.416 | FAP (PF07174, IPR010801): Fibronectin-attachment protein (FAP) Gastrin (PF00918, IPR001651, SM00029): Gastrin/cholecystokinin family DUF2162 (PF09930, IPR017199): Predicted transporter (DUF2162) Angiomotin_C (PF12240, IPR024646): Angiomotin C terminal SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3 |
15 |
ANGPTL4 | suppressor | 6 | 0.867 | 0.364 | SlyX (PF04102, IPR007236): SlyX Fibrinogen_C (PF00147, IPR002181, SM00186): Fibrinogen beta and gamma chains, C-terminal globular domain |
16 |
ANXA7 | suppressor | 11 | 0.400 | 10.402 | Annexin (PF00191, IPR018502, SM00335): Annexin |
17 |
AP2M1 | protein found in more fusions | 25 | 0.446 | 47.657 | Adap_comp_sub (PF00928, IPR008968): Adaptor complexes medium subunit family Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain |
18 |
AR | oncoprotein | 26 | 0.257 | 105.765 | Androgen_recep (PF02166, IPR001103): Androgen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
19 |
ARRB2 | interactor | 24 | 0.395 | 52.847 | Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain |
20 |
ASB12 | interactor | 3 | 0.667 | 0.286 | Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_3 (PF13606, IPR002110): Ankyrin repeat SOCS_box (PF07525, IPR001496): SOCS box |
21 |
ASB9 | interactor | 3 | 0.667 | 0.333 | Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies) SOCS_box (PF07525, IPR001496): SOCS box |
22 |
ATF3 | suppressor | 9 | 0.571 | 4.395 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor |
23 |
BBS4 | interactor | 4 | 0.667 | 0.733 | TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat Mu-like_Pro (PF10123, IPR012106): Mu-like prophage I protein TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat |
24 |
BCL2L1 | oncoprotein | 9 | 0.571 | 2.932 | Bcl-2 (PF00452, IPR026298): Apoptosis regulator proteins, Bcl-2 family BH4 (PF02180, IPR003093, SM00265): Bcl-2 homology region 4 |
25 |
BCL7C | suppressor | 5 | 0.700 | 1.000 | BCL_N (PF04714, IPR006804): BCL7, N-terminal conserver region |
26 |
CAD | oncoprotein | 24 | 0.315 | 67.456 | Amidohydro_1 (PF01979, IPR006680): Amidohydrolase family CPSase_L_D2 (PF02786, IPR005479): Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 (PF02787, IPR005480, SM01096): Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_sm_chain (PF00988, IPR002474, SM01097): Carbamoyl-phosphate synthase small chain, CPSase domain GATase (PF00117, IPR017926): Glutamine amidotransferase class-I MGS (PF02142, IPR011607, SM00851): MGS-like domain OTCace (PF00185, IPR006131): Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N (PF02729, IPR006132): Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain ATPgrasp_Ter (PF15632, IPR011226): ATP-grasp in the biosynthetic pathway with Ter operon |
27 |
CAND1 | interactor | 38 | 0.371 | 149.551 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981) HEAT (PF02985, IPR000357): HEAT repeat TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20) RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II |
28 |
CAP2 | interactor | 5 | 1.000 | 0 | CAP_C (PF08603, IPR013912): Adenylate cyclase associated (CAP) C terminal CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator |
29 |
CARM1 | oncoprotein | 16 | 0.542 | 14.707 | K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase CBP_GIL (PF10995, IPR017745): GGDEF I-site like or GIL domain CARM1 (PF11531, IPR020989): Coactivator-associated arginine methyltransferase 1 N terminal |
30 |
CAV1 | suppressor | 14 | 0.330 | 28.835 | Caveolin (PF01146, IPR001612): Caveolin |
31 |
CBL | suppressor | 19 | 0.451 | 39.184 | Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1 Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain Prok-RING_4 (PF14447): Prokaryotic RING finger family 4 zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain |
32 |
CCT2 | interactor | 35 | 0.343 | 110.263 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
33 |
CCT5 | interactor | 28 | 0.336 | 84.927 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
34 |
CD81 | interactor | 17 | 0.300 | 36.486 | Tetraspannin (PF00335, IPR018499): Tetraspanin family |
35 |
CDC5L | interactor | 47 | 0.307 | 259.993 | OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain |
36 |
CDK2 | suppressor | 56 | 0.294 | 382.595 | Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain |
37 |
CDKN1A | suppressor | 25 | 0.363 | 78.121 | CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor |
38 |
CDKN2A | suppressor | 20 | 0.400 | 38.433 | Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies) |
39 |
CENPA | interactor | 8 | 0.667 | 1.078 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
40 |
CEP250 | interactor | 14 | 0.363 | 21.306 | ACCA (PF03255, IPR001095): Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DASH_Dam1 (PF08653, IPR013962): DASH complex subunit Dam1 DivIC (PF04977, IPR007060): Septum formation initiator DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) EHN (PF06441, IPR010497): Epoxide hydrolase N terminus ERM (PF00769, IPR011259): Ezrin/radixin/moesin family Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family IncA (PF04156, IPR007285): IncA protein Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain SlyX (PF04102, IPR007236): SlyX Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal TSC22 (PF01166, IPR000580): TSC-22/dip/bun family CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Endonuc_Holl (PF10107, IPR019287): Endonuclease related to archaeal Holliday junction resolvase DUF2570 (PF10828, IPR022538): Protein of unknown function (DUF2570) DGF-1_C (PF11040, IPR021053): Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968) DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404) DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472) Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion KAsynt_C_assoc (PF16197, IPR032821): Ketoacyl-synthetase C-terminal extension HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 |
41 |
CFL1 | interactor | 32 | 0.341 | 145.758 | Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein |
42 |
CFL2 | interactor | 16 | 0.610 | 19.487 | Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein |
43 |
COPS5 | protein found in more fusions | 34 | 0.498 | 53.318 | JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease |
44 |
COPS6 | interactor | 22 | 0.457 | 35.939 | DUF320 (PF03777, IPR005528): Small secreted domain (DUF320) JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function |
45 |
CORO1B | interactor | 16 | 0.675 | 14.585 | DUF1899 (PF08953, IPR015048, SM01166): Domain of unknown function (DUF1899) Trimer_CC (PF08954, IPR015049, SM01167): Trimerisation motif WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain WD40_4 (PF16300): Type of WD40 repeat |
46 |
CORO1C | oncoprotein | 30 | 0.437 | 75.501 | DUF1899 (PF08953, IPR015048, SM01166): Domain of unknown function (DUF1899) WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat WD40_4 (PF16300): Type of WD40 repeat |
47 |
CORO7 | interactor | 4 | 0.667 | 0.583 | DUF1899 (PF08953, IPR015048, SM01166): Domain of unknown function (DUF1899) WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain WD40_4 (PF16300): Type of WD40 repeat |
48 |
COTL1 | oncoprotein | 4 | 0.667 | 0.325 | Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein |
49 |
CRK | oncoprotein | 23 | 0.316 | 83.479 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
50 |
CSNK2B | interactor | 19 | 0.294 | 45.799 | CK_II_beta (PF01214, IPR000704, SM01085): Casein kinase II regulatory subunit |
51 |
CTGF | suppressor | 2 | 1.000 | 0 | Cys_knot (PF00007, IPR006208): Cystine-knot domain VWC (PF00093, IPR001007, SM00214): von Willebrand factor type C domain IGFBP (PF00219, IPR000867, SM00121): Insulin-like growth factor binding protein TSP_1 (PF00090, IPR000884, SM00209): Thrombospondin type 1 domain |
52 |
CUL1 | suppressor | 44 | 0.401 | 174.603 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
53 |
CUL2 | suppressor | 28 | 0.471 | 55.051 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
54 |
CUL3 | protein found in more fusions | 61 | 0.268 | 519.666 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal |
55 |
CUL5 | suppressor | 31 | 0.396 | 148.229 | Cullin (PF00888, IPR001373, SM00182): Cullin family GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
56 |
CYBB | interactor | 2 | 1.000 | 0 | FAD_binding_8 (PF08022, IPR013112): FAD-binding domain Ferric_reduct (PF01794, IPR013130): Ferric reductase like transmembrane component NAD_binding_6 (PF08030, IPR013121): Ferric reductase NAD binding domain |
57 |
DAB2 | suppressor | 13 | 0.744 | 4.968 | PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) zf-C2H2_assoc3 (PF16637): Putative zinc-finger between two C2H2 zinc-fingers on Patz |
58 |
DHX9 | oncoprotein | 39 | 0.323 | 162.625 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold T2SSE (PF00437, IPR001482): Type II/IV secretion system protein HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
59 |
DMAP1 | interactor | 10 | 0.800 | 2.662 | DMAP1 (PF05499, IPR008468): DNA methyltransferase 1-associated protein 1 (DMAP1) SANT_DAMP1_like (PF16282, IPR032563): SANT/Myb-like domain of DAMP1 |
60 |
DSTN | interactor | 15 | 0.314 | 44.103 | Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein |
61 |
DTNA | interactor | 2 | 1.000 | 0 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) CRISPR_Cse2 (PF09485, IPR013382): CRISPR-associated protein Cse2 (CRISPR_cse2) EF-hand_2 (PF09068, IPR015153): EF hand EF-hand_3 (PF09069, IPR015154): EF-hand PMC2NT (PF08066, IPR012588): PMC2NT (NUC016) domain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type |
62 |
DUSP19 | interactor | 2 | 1.000 | 0 | DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain |
63 |
EEF1A1 | suppressor | 69 | 0.166 | 960.106 | GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain |
64 |
EEF1A2 | oncoprotein | 25 | 0.283 | 79.687 | GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain |
65 |
EHHADH | interactor | 3 | 0.667 | 0.667 | 2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH (PF00725, IPR006108): 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 3HCDH_N (PF02737, IPR006176): 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 (PF00378, IPR001753): Enoyl-CoA hydratase/isomerase |
66 |
EIF4A3 | interactor | 22 | 0.510 | 30.518 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
67 |
ELAVL1 | oncoprotein | 56 | 0.173 | 708.186 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
68 |
EMD | interactor | 16 | 0.371 | 25.597 | LEM (PF03020, IPR003887, SM00540): LEM domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein |
69 |
ENC1 | oncoprotein | 4 | 0.667 | 0.500 | BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain HTH_12 (PF08461, IPR013668): Ribonuclease R winged-helix domain Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif |
70 |
EP300 | oncoprotein | 31 | 0.317 | 138.014 | Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type |
71 |
EPS15 | oncoprotein | 18 | 0.529 | 20.392 | Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391) EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand EF-hand_7 (PF13499, IPR011992): EF-hand domain pair |
72 |
ERBB2 | oncoprotein | 13 | 0.470 | 17.645 | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV |
73 |
ERBB3 | oncoprotein | 16 | 0.390 | 30.072 | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV |
74 |
ERG | oncoprotein | 11 | 0.491 | 5.707 | Ets (PF00178, IPR000418, SM00413): Ets-domain SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain |
75 |
ERRFI1 | suppressor | 10 | 0.611 | 4.511 | GTPase_binding (PF09027, IPR015116): GTPase binding Inhibitor_Mig-6 (PF11555, IPR021619): EGFR receptor inhibitor Mig-6 |
76 |
ESR1 | suppressor | 59 | 0.221 | 556.825 | Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal |
77 |
ESR2 | suppressor | 11 | 0.556 | 6.456 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ERbeta_N (PF12497, IPR021064): Estrogen receptor beta |
78 |
FABP4 | interactor | 2 | 1.000 | 0 | Lipocalin (PF00061, IPR000566): Lipocalin / cytosolic fatty-acid binding protein family |
79 |
FBXO25 | suppressor | 17 | 0.338 | 30.383 | Elongin_A (PF06881, IPR010684): RNA polymerase II transcription factor SIII (Elongin) subunit A |
80 |
FHOD1 | interactor | 10 | 0.389 | 8.963 | Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator FH2 (PF02181, IPR015425, SM00498): Formin Homology 2 Domain |
81 |
FLNA | suppressor | 53 | 0.285 | 421.754 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Filamin (PF00630, IPR017868): Filamin/ABP280 repeat |
82 |
FN1 | oncoprotein | 49 | 0.264 | 327.255 | fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) |
83 |
FPR1 | interactor | 1 | 0 | 0 | 7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) Phage_holin_2_1 (PF04971, IPR007054): Bacteriophage P21 holin S |
84 |
FUS | suppressor | 40 | 0.409 | 133.847 | Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others Limkain-b1 (PF11608, IPR024582): Limkain b1 FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head |
85 |
GRB2 | oncoprotein | 47 | 0.268 | 354.782 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093) |
86 |
H2AFX | suppressor | 23 | 0.304 | 63.069 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A |
87 |
HAUS1 | interactor | 7 | 0.467 | 2.282 | THP2 (PF09432, IPR018557): Tho complex subunit THP2 XhlA (PF10779, IPR019715): Haemolysin XhlA DUF3496 (PF12001, IPR021885): Domain of unknown function (DUF3496) |
88 |
HCK | oncoprotein | 6 | 0.400 | 3.608 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
89 |
HDAC6 | oncoprotein | 20 | 0.205 | 64.662 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain PSGP (PF07276, IPR009900): Apopolysialoglycoprotein (PSGP) zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein |
90 |
HMMR | interactor | 3 | 0.667 | 0.400 | APG6 (PF04111, IPR007243): Autophagy protein Apg6 Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family ApoO (PF09769, IPR019166): Apolipoprotein O Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5 HMMR_N (PF15905, IPR031787): Hyaluronan mediated motility receptor N-terminal HMMR_C (PF15908, IPR031794): Hyaluronan mediated motility receptor C-terminal |
91 |
HNF1A | oncoprotein | 5 | 0.667 | 0.417 | HNF-1_N (PF04814, IPR006899): Hepatocyte nuclear factor 1 (HNF-1), N terminus HNF-1A_C (PF04813, IPR006898): Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus HNF-1B_C (PF04812, IPR006897): Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
92 |
HNRNPA1 | interactor | 58 | 0.320 | 409.699 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1 |
93 |
HNRNPD | oncoprotein | 42 | 0.332 | 158.732 | CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Keratin_2_head (PF16208, IPR032444): Keratin type II head |
94 |
HNRNPU | interactor | 64 | 0.241 | 608.990 | CDC45 (PF02724, IPR003874): CDC45-like protein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SAP (PF02037, IPR003034, SM00513): SAP domain SPRY (PF00622, IPR003877, SM00449): SPRY domain AAA_33 (PF13671): AAA domain WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
95 |
HOMER1 | interactor | 3 | 1.000 | 0 | WH1 (PF00568, IPR000697, SM00461): WH1 domain TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding |
96 |
HOXB5 | interactor | 3 | 0.667 | 0.333 | DUF739 (PF05339, IPR008003): Protein of unknown function (DUF739) Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
97 |
HSD17B3 | interactor | 1 | 0 | 0 | adh_short (PF00106, IPR002198): short chain dehydrogenase |
98 |
HSPA5 | oncoprotein | 65 | 0.247 | 627.118 | HSP70 (PF00012, IPR013126): Hsp70 protein |
99 |
HSPB2 | interactor | 8 | 0.381 | 5.577 | Crystallin (PF00525, IPR003090): Alpha crystallin A chain, N terminal HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family |
100 |
ICAM1 | oncoprotein | 5 | 0.900 | 0.087 | Adhes-Ig_like (PF09085, IPR015169): Adhesion molecule, immunoglobulin-like C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain ICAM_N (PF03921, IPR013768): Intercellular adhesion molecule (ICAM), N-terminal domain Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain |
101 |
ICAM3 | interactor | 1 | 0 | 0 | C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain ICAM_N (PF03921, IPR013768): Intercellular adhesion molecule (ICAM), N-terminal domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Ig_2 (PF13895, IPR007110): Immunoglobulin domain |
102 |
INO80 | interactor | 4 | 1.000 | 0 | Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein RNA_pol_Rbc25 (PF08292, IPR013238): RNA polymerase III subunit Rpc25 SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain POTRA (PF07244, IPR010827): Surface antigen variable number repeat Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain DBINO (PF13892, IPR020838): DNA-binding domain FAM176 (PF14851): FAM176 family MAP17 (PF15807, IPR031627): Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 |
103 |
IQCB1 | interactor | 11 | 0.382 | 9.423 | DUF1765 (PF08578, IPR013887): Protein of unknown function (DUF1765) IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif HJURP_C (PF12347, IPR022102): Holliday junction regulator protein family C-terminal repeat Condensin2nSMC (PF12422, IPR024741): Condensin II non structural maintenance of chromosomes subunit |
104 |
IQGAP1 | interactor | 57 | 0.268 | 515.203 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain DUF87 (PF01935, IPR002789): Domain of unknown function DUF87 IDEAL (PF08858, IPR014957, SM00914): IDEAL domain IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase RasGAP_C (PF03836, IPR000593): RasGAP C-terminus WW (PF00397, IPR001202, SM00456): WW domain |
105 |
ISG15 | suppressor | 16 | 0.333 | 22.102 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
106 |
ITGA4 | interactor | 37 | 0.319 | 139.145 | FG-GAP (PF01839, IPR013517): FG-GAP repeat Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region Integrin_alpha2 (PF08441, IPR013649): Integrin alpha |
107 |
IVNS1ABP | protein found in more fusions | 13 | 0.652 | 3.606 | BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif |
108 |
KAT2B | protein found in more fusions | 22 | 0.367 | 76.564 | Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain |
109 |
KAT5 | suppressor | 23 | 0.394 | 62.035 | MOZ_SAS (PF01853, IPR002717): MOZ/SAS family Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain |
110 |
KHDRBS1 | protein found in more fusions | 26 | 0.243 | 129.520 | KH_1 (PF00013, IPR004088, SM00322): KH domain Qua1 (PF16274, IPR032571): Qua1 domain Sam68-YY (PF16568, IPR032335): Tyrosine-rich domain of Sam68 |
111 |
LGALS3BP | oncoprotein | 25 | 0.409 | 52.511 | BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch SRCR (PF00530, IPR001190): Scavenger receptor cysteine-rich domain SRCR_2 (PF15494, IPR017448): Scavenger receptor cysteine-rich domain |
112 |
LGR4 | interactor | 13 | 0.379 | 8.844 | 7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) LRR_1 (PF00560, IPR001611): Leucine Rich Repeat LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat |
113 |
LIMA1 | suppressor | 33 | 0.422 | 94.230 | LIM (PF00412, IPR001781, SM00132): LIM domain ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain |
114 |
LMX1B | interactor | 1 | 0 | 0 | LIM (PF00412, IPR001781, SM00132): LIM domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain PNISR (PF15996, IPR031937): Arginine/serine-rich protein PNISR |
115 |
LRRK2 | oncoprotein | 15 | 0.396 | 27.561 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain DUF1043 (PF06295, IPR009386): Protein of unknown function (DUF1043) T2SSE (PF00437, IPR001482): Type II/IV secretion system protein Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase Pkinase (PF00069, IPR000719): Protein kinase domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) PQQ_2 (PF13360, IPR002372): PQQ-like domain LRR_8 (PF13855, IPR001611): Leucine rich repeat COR (PF16095, IPR032171): C-terminal of Roc, COR, domain |
116 |
MAGEA10 | interactor | 2 | 1.000 | 0 | MAGE (PF01454, IPR002190): MAGE family SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal |
117 |
MAGOH | interactor | 9 | 0.694 | 2.006 | Mago_nashi (PF02792, IPR004023): Mago nashi protein |
118 |
MAP1A | interactor | 3 | 0.667 | 0.500 | Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) DUF572 (PF04502, IPR007590): Family of unknown function (DUF572) DUF3552 (PF12072, IPR022711): Domain of unknown function (DUF3552) Lactamase_B_6 (PF16661, IPR001279): Metallo-beta-lactamase superfamily domain |
119 |
MAP2 | oncoprotein | 5 | 0.667 | 0.515 | MAP2_projctn (PF08377, IPR013588): MAP2/Tau projection domain Tubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeat RII_binding_1 (PF10522, IPR018459): RII binding domain CCSAP (PF15748, IPR029774): Centriole, cilia and spindle-associated |
120 |
MAPK7 | oncoprotein | 4 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain Rrn6 (PF10214, IPR019350): RNA polymerase I-specific transcription-initiation factor |
121 |
MDM2 | oncoprotein | 34 | 0.309 | 155.743 | Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region Presenilin (PF01080, IPR001108): Presenilin SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
122 |
MEPCE | protein found in more fusions | 14 | 0.505 | 9.860 | Bin3 (PF06859, IPR010675): Bicoid-interacting protein 3 (Bin3) Methyltransf_23 (PF13489): Methyltransferase domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 DLEU7 (PF15760, IPR031510): Leukemia-associated protein 7 |
123 |
MGMT | interactor | 8 | 0.643 | 2.751 | DNA_binding_1 (PF01035, IPR014048): 6-O-methylguanine DNA methyltransferase, DNA binding domain Methyltransf_1N (PF02870, IPR008332): 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain |
124 |
MKL1 | oncoprotein | 3 | 1.000 | 0 | RPEL (PF02755, IPR004018, SM00707): RPEL repeat SAP (PF02037, IPR003034, SM00513): SAP domain Troponin-I_N (PF11636, IPR021666): Troponin I residues 1-32 |
125 |
MORF4L1 | interactor | 13 | 0.667 | 5.484 | MRG (PF05712, IPR026541): MRG Fmp27_WPPW (PF10359, IPR019449): RNA pol II promoter Fmp27 protein domain Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain |
126 |
MORF4L2 | interactor | 12 | 0.667 | 7.302 | MRG (PF05712, IPR026541): MRG |
127 |
MRGBP | interactor | 10 | 0.778 | 1.862 | Eaf7 (PF07904, IPR012423): Chromatin modification-related protein EAF7 |
128 |
MYC | oncoprotein | 35 | 0.346 | 133.799 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region |
129 |
MYH11 | oncoprotein | 14 | 0.275 | 22.922 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator |
130 |
MYH9 | suppressor | 61 | 0.261 | 585.008 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) |
131 |
MYO18A | interactor | 27 | 0.484 | 72.362 | Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1 IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_tail_1 (PF01576, IPR002928): Myosin tail PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2 |
132 |
MYOC | interactor | 8 | 0.476 | 4.541 | IncA (PF04156, IPR007285): IncA protein OLF (PF02191, IPR003112, SM00284): Olfactomedin-like domain |
133 |
NCALD | interactor | 1 | 0 | 0 | EF-hand_7 (PF13499, IPR011992): EF-hand domain pair EF-hand_8 (PF13833, IPR002048): EF-hand domain pair |
134 |
NCF1 | interactor | 4 | 0.667 | 0.333 | p47_phox_C (PF08944, IPR015039): NADPH oxidase subunit p47Phox, C terminal domain PX (PF00787, IPR001683, SM00312): PX domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain NECFESHC (PF16621, IPR032136): SH3 terminal domain of 2nd SH3 on Neutrophil cytosol factor 1 |
135 |
NEDD1 | interactor | 11 | 0.564 | 5.126 | NRBF2 (PF08961, IPR015056): Nuclear receptor-binding factor 2, autophagy regulator eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A FliM (PF02154, IPR001689): Flagellar motor switch protein FliM WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Mto2_bdg (PF12808, IPR024545): Micro-tubular organiser Mto1 C-term Mto2-binding region ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
136 |
NEDD8 | interactor | 23 | 0.576 | 33.548 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
137 |
NOS3 | interactor | 6 | 0.400 | 2.805 | FAD_binding_1 (PF00667, IPR003097): FAD binding domain Flavodoxin_1 (PF00258, IPR008254): Flavodoxin NAD_binding_1 (PF00175, IPR001433): Oxidoreductase NAD-binding domain NO_synthase (PF02898, IPR004030): Nitric oxide synthase, oxygenase domain HTH_15 (PF12324, IPR024259): Helix-turn-helix domain of alkylmercury lyase |
138 |
NSMAF | interactor | 4 | 1.000 | 0 | Beach (PF02138, IPR000409, SM01026): Beige/BEACH domain GRAM (PF02893, IPR004182, SM00568): GRAM domain NABP (PF07990, IPR012940): Nucleic acid binding protein NABP WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain PH_BEACH (PF14844, IPR023362): PH domain associated with Beige/BEACH |
139 |
OSTF1 | interactor | 5 | 0.400 | 3.867 | SH3_1 (PF00018, IPR001452, SM00326): SH3 domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) |
140 |
OTUB1 | interactor | 18 | 0.275 | 57.461 | Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain |
141 |
PA2G4 | interactor | 14 | 0.374 | 21.514 | Peptidase_M24 (PF00557, IPR001714): Metallopeptidase family M24 Ribosomal_S25 (PF03297, IPR004977): S25 ribosomal protein TraC (PF07820, IPR012930): TraC-like protein |
142 |
PAN2 | interactor | 29 | 0.337 | 86.985 | RNase_T (PF00929, IPR013520): Exonuclease UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase WD40_like (PF17005, IPR031544): WD40-like domain |
143 |
PARK2 | suppressor | 28 | 0.293 | 113.023 | IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
144 |
PCK1 | interactor | 8 | 0.464 | 3.528 | PEPCK (PF00821, IPR008209): Phosphoenolpyruvate carboxykinase |
145 |
PCYT1B | interactor | 1 | 0 | 0 | ApoC-I (PF04691, IPR006781): Apolipoprotein C-I (ApoC-1) CTP_transf_like (PF01467, IPR004821): Cytidylyltransferase-like FTO_CTD (PF12934, IPR024366): FTO C-terminal domain |
146 |
PFN1 | suppressor | 18 | 0.412 | 40.176 | Profilin (PF00235, IPR005455, SM00392): Profilin |
147 |
PHB | suppressor | 17 | 0.353 | 32.035 | Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family DUF4290 (PF14123, IPR025632): Domain of unknown function (DUF4290) |
148 |
PIK3R2 | oncoprotein | 19 | 0.515 | 26.229 | RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain PI3K_P85_iSH2 (PF16454, IPR032498): Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain |
149 |
PLG | interactor | 4 | 0.667 | 0.508 | Kringle (PF00051, IPR000001): Kringle domain PAN_1 (PF00024, IPR003014): PAN domain Trypsin (PF00089, IPR001254, SM00020): Trypsin |
150 |
PNMA1 | oncoprotein | 4 | 0.500 | 2.667 | PNMA (PF14893, IPR026523): PNMA |
151 |
POLR1B | interactor | 8 | 0.429 | 7.019 | RNA_pol_Rpa2_4 (PF06883, IPR009674): RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_1 (PF04563, IPR007644): RNA polymerase beta subunit RNA_pol_Rpb2_3 (PF04565, IPR007645): RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_6 (PF00562, IPR007120): RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 (PF04560, IPR007641): RNA polymerase Rpb2, domain 7 |
152 |
POLR2A | protein found in more fusions | 31 | 0.308 | 115.310 | RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat |
153 |
POT1 | interactor | 11 | 0.267 | 24.375 | POT1 (PF02765, IPR011564, SM00976): Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain POT1PC (PF16686, IPR032042): ssDNA-binding domain of telomere protection protein |
154 |
PPP1CA | suppressor | 33 | 0.348 | 99.336 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain |
155 |
PPP1CB | interactor | 35 | 0.360 | 144.015 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain |
156 |
PPP1CC | oncoprotein | 30 | 0.451 | 64.150 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain |
157 |
PROM1 | interactor | 1 | 0 | 0 | Prominin (PF05478, IPR008795): Prominin |
158 |
PROSER2 | interactor | 2 | 1.000 | 0 | SARG (PF15385): Specifically androgen-regulated gene protein |
159 |
PRSS23 | interactor | 3 | 0.667 | 0.143 | Trypsin (PF00089, IPR001254, SM00020): Trypsin |
160 |
PSMA3 | interactor | 20 | 0.427 | 27.879 | Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature |
161 |
PSTPIP1 | interactor | 4 | 0.500 | 1.417 | ABATE (PF07336, IPR010852): Putative stress-induced transcription regulator FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain WXG100 (PF06013, IPR010310): Proteins of 100 residues with WXG Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5 |
162 |
RAB2A | oncoprotein | 10 | 0.511 | 10.626 | Ras (PF00071, IPR001806, SM00173): Ras family |
163 |
RAB8B | oncoprotein | 5 | 0.400 | 3.786 | Ras (PF00071, IPR001806, SM00173): Ras family |
164 |
RAC1 | oncoprotein | 16 | 0.438 | 20.213 | Ras (PF00071, IPR001806, SM00173): Ras family |
165 |
RAC2 | oncoprotein | 5 | 0.600 | 0.746 | Ras (PF00071, IPR001806, SM00173): Ras family |
166 |
RAD52 | oncoprotein | 8 | 0.667 | 1.809 | Rad52_Rad22 (PF04098, IPR007232): Rad52/22 family double-strand break repair protein DUF2335 (PF10097, IPR019284): Predicted membrane protein (DUF2335) |
167 |
RCC1 | interactor | 7 | 0.524 | 2.179 | RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat |
168 |
RPA1 | suppressor | 45 | 0.315 | 252.541 | Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain |
169 |
RPA2 | oncoprotein | 33 | 0.405 | 92.552 | RPA_C (PF08784, IPR014892): Replication protein A C terminal tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2 |
170 |
RPA3 | interactor | 32 | 0.383 | 87.261 | Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3 |
171 |
RPL10A | interactor | 21 | 0.448 | 21.218 | Ribosomal_L1 (PF00687, IPR028364): Ribosomal protein L1p/L10e family |
172 |
RUVBL1 | oncoprotein | 37 | 0.254 | 209.395 | TIP49 (PF06068, IPR010339): TIP49 C-terminus |
173 |
RUVBL2 | oncoprotein | 42 | 0.295 | 215.513 | TIP49 (PF06068, IPR010339): TIP49 C-terminus |
174 |
SAMHD1 | interactor | 11 | 0.511 | 5.796 | HD (PF01966, IPR006674): HD domain SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) |
175 |
SCARNA22 | interactor | 9 | 0.639 | 1.960 | NA |
176 |
SHBG | oncoprotein | 9 | 0.321 | 10.632 | Laminin_G_1 (PF00054, IPR001791): Laminin G domain Laminin_G_2 (PF02210, IPR001791): Laminin G domain |
177 |
SHC1 | oncoprotein | 27 | 0.394 | 73.053 | PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) SH2 (PF00017, IPR000980, SM00252): SH2 domain |
178 |
SKI | oncoprotein | 10 | 0.639 | 2.723 | c-SKI_SMAD_bind (PF08782, IPR014890, SM01046): c-SKI Smad4 binding domain Ski_Sno (PF02437, IPR003380): SKI/SNO/DAC family SlyX (PF04102, IPR007236): SlyX HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 |
179 |
SLC12A3 | interactor | 1 | 0 | 0 | AA_permease (PF00324, IPR004841): Amino acid permease AA_permease_N (PF08403, IPR013612): Amino acid permease N-terminal SLC12 (PF03522, IPR018491): Solute carrier family 12 |
180 |
SLC30A6 | interactor | 2 | 1.000 | 0 | Cation_efflux (PF01545, IPR002524): Cation efflux family |
181 |
SLC6A2 | interactor | 2 | 1.000 | 0 | SNF (PF00209, IPR000175): Sodium:neurotransmitter symporter family |
182 |
SMAD3 | oncoprotein | 28 | 0.291 | 128.854 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
183 |
SMAD9 | interactor | 7 | 0.533 | 2.458 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
184 |
SMARCA4 | suppressor | 25 | 0.297 | 106.573 | DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) HSA (PF07529, IPR014012, SM00573): HSA QLQ (PF08880, IPR014978, SM00951): QLQ SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain BRK (PF07533, IPR006576, SM00592): BRK domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal DUF4065 (PF13274, IPR025272): Protein of unknown function (DUF4065) SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
185 |
SMARCC2 | interactor | 17 | 0.390 | 34.541 | GHMP_kinases_N (PF00288, IPR006204): GHMP kinases N terminal domain SWIRM (PF04433, IPR007526): SWIRM domain DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1 SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal |
186 |
SMARCE1 | interactor | 11 | 0.545 | 9.912 | DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) GCN5L1 (PF06320, IPR009395): GCN5-like protein 1 (GCN5L1) Ndc1_Nup (PF09531, IPR019049): Nucleoporin protein Ndc1-Nup HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box Ferlin_C (PF16165, IPR032362): Ferlin C-terminus |
187 |
SMN1 | interactor | 16 | 0.390 | 25.612 | SMN (PF06003, IPR010304): Survival motor neuron protein (SMN) |
188 |
SMURF1 | interactor | 20 | 0.474 | 16.474 | C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) |
189 |
SNCA | interactor | 12 | 0.345 | 24.095 | Synuclein (PF01387, IPR001058): Synuclein |
190 |
SNW1 | protein found in more fusions | 43 | 0.319 | 221.199 | SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term SIR4_SID (PF16991, IPR031556): Sir4 SID domain |
191 |
SPTBN2 | interactor | 8 | 1.000 | 0 | BEX (PF04538, IPR021156): Brain expressed X-linked like family CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Spectrin (PF00435, IPR002017): Spectrin repeat Mating_N (PF12731, IPR024333): Mating-type protein beta 1 DUF4110 (PF13422, IPR025183): Domain of unknown function (DUF4110) PH_9 (PF15410): Pleckstrin homology domain |
192 |
SRPK2 | oncoprotein | 13 | 0.439 | 12.614 | DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387) Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator Pkinase (PF00069, IPR000719): Protein kinase domain S-antigen (PF05756, IPR008825): S-antigen protein DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) |
193 |
SSH1 | interactor | 3 | 0.667 | 0.400 | DEK_C (PF08766, IPR014876): DEK C terminal domain DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain |
194 |
SSH2 | interactor | 9 | 0.833 | 0.999 | DEK_C (PF08766, IPR014876): DEK C terminal domain DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain |
195 |
STAU1 | protein found in more fusions | 28 | 0.405 | 51.272 | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Staufen_C (PF16482, IPR032478): Staufen C-terminal domain |
196 |
SVIL | interactor | 16 | 0.575 | 22.761 | Gelsolin (PF00626, IPR007123): Gelsolin repeat VHP (PF02209, IPR003128, SM00153): Villin headpiece domain DUF4695 (PF15766, IPR031521): Domain of unknown function (DUF4695) |
197 |
SYNPO | interactor | 23 | 0.597 | 23.123 | Calsarcin (PF05556, IPR008438): Calcineurin-binding protein (Calsarcin) |
198 |
TAF11 | interactor | 3 | 1.000 | 0 | CENP-X (PF09415, IPR018552): CENP-S associating Centromere protein X TAFII28 (PF04719, IPR006809): hTAFII28-like protein conserved region |
199 |
TCP1 | interactor | 34 | 0.308 | 122.918 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
200 |
TINF2 | interactor | 6 | 0.600 | 3.400 | TINF2_N (PF14973, IPR029400): TERF1-interacting nuclear factor 2 N-terminus |
201 |
TJP1 | interactor | 8 | 0.464 | 11.673 | DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) SH3_2 (PF07653, IPR011511): Variant SH3 domain ZU5 (PF00791, IPR000906, SM00218): ZU5 domain Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase RPOL_N (PF14700, IPR029262): DNA-directed RNA polymerase N-terminal |
202 |
TK1 | oncoprotein | 11 | 0.444 | 8.426 | TK (PF00265, IPR001267, SM00203): Thymidine kinase |
203 |
TP53 | suppressor | 58 | 0.244 | 545.420 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif |
204 |
TPST1 | interactor | 1 | 0 | 0 | Sulfotransfer_3 (PF13469): Sulfotransferase family |
205 |
TRAF3IP1 | interactor | 7 | 0.429 | 5.611 | MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 |
206 |
TRIM15 | suppressor | 11 | 0.267 | 20.071 | Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger zf-C4pol (PF14260, IPR025687): C4-type zinc-finger of DNA polymerase delta |
207 |
TTR | interactor | 5 | 0.500 | 0.715 | Transthyretin (PF00576, IPR023416, SM00095): HIUase/Transthyretin family |
208 |
TUBG1 | protein found in more fusions | 27 | 0.363 | 85.058 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
209 |
TUBGCP2 | interactor | 13 | 0.423 | 16.658 | Spc97_Spc98 (PF04130, IPR007259): Spc97 / Spc98 family zf-Tim10_DDP (PF02953, IPR004217): Tim10/DDP family zinc finger |
210 |
TUBGCP3 | interactor | 13 | 0.628 | 6.467 | Spc97_Spc98 (PF04130, IPR007259): Spc97 / Spc98 family |
211 |
UBASH3B | interactor | 19 | 0.497 | 20.444 | His_Phos_1 (PF00300, IPR013078, SM00855): Histidine phosphatase superfamily (branch 1) UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain 2_5_RNA_ligase2 (PF13563): 2'-5' RNA ligase superfamily SH3_9 (PF14604, IPR001452): Variant SH3 domain |
212 |
UBE3A | oncoprotein | 12 | 0.436 | 15.135 | HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) PCM1_C (PF15717, IPR031446): Pericentriolar material 1 C terminus AZUL (PF16558, IPR032353): Amino-terminal Zinc-binding domain of ubiquitin ligase E3A |
213 |
UBL4A | interactor | 16 | 0.350 | 27.643 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
214 |
UCHL5 | oncoprotein | 16 | 0.352 | 31.768 | Peptidase_C12 (PF01088, IPR001578): Ubiquitin carboxyl-terminal hydrolase, family 1 |
215 |
UNK | interactor | 14 | 0.363 | 19.733 | MbeD_MobD (PF04899, IPR006983): MbeD/MobD like NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) zf-CCCH_2 (PF14608): RNA-binding, Nab2-type zinc finger Torus (PF16131, IPR032297): Torus domain |
216 |
USP46 | interactor | 2 | 1.000 | 0 | UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase |
217 |
VCAM1 | interactor | 36 | 0.286 | 128.393 | C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain |
218 |
VCP | protein found in more fusions | 48 | 0.268 | 344.292 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2 CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain TniB (PF05621, IPR008868): Bacterial TniB protein Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944) |
219 |
VHL | suppressor | 28 | 0.444 | 48.639 | Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) VHL (PF01847, IPR022772): von Hippel-Lindau disease tumour suppressor protein VHL_C (PF17211): VHL box domain |
220 |
WDYHV1 | interactor | 6 | 0.333 | 6.586 | Nt_Gln_amidase (PF09764, IPR023128): N-terminal glutamine amidase |
221 |
YARS | interactor | 8 | 0.643 | 0.978 | tRNA-synt_1b (PF00579, IPR002305): tRNA synthetases class I (W and Y) tRNA_bind (PF01588, IPR002547): Putative tRNA binding domain |
222 |
YWHAQ | interactor | 47 | 0.247 | 346.097 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
223 |
ZBTB1 | interactor | 3 | 1.000 | 0 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-BED (PF02892, IPR003656, SM00614): BED zinc finger zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies) zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger |