Find Fusion Network

Visualization interactions

Powered by Cytoscape Web for: parental proteins ZNF331, ACTA2 (from a repository: Fri Aug 16 10:08:02 2019)

Examples AFF1 MLL ACTN4 + MLLAFF1 + MLLALK + MSNALK + TFGALK + TPM3ALK + TPM4ASXL2 + KAT6AATF1 + FUSBCR + ABL1BCR + FGFR1CCND1 + TACSTD2CD74 + ROS1CDK6 + MLLCOL1A1 + PDGFBCREB3L2 + PPARGCREB3L2 + FUSCREBBP + KAT6ADAZAP1 + MEF2DELL + MLLEPS15 + MLLERG + EWSR1ERG + FUSERG + TMPRSS2ETV5 + TMPRSS2ETV6 + ABL1ETV6 + NTRK3ETV6 + PAX5EWSR1 + FLI1EWSR1 + WT1FOXO1 + PAX3FOXP1 + PAX5FRYL + MLLGAS7 + MLLGMPS + MLLGOLGA5 + RETHOOK3 + RETHOXC13 + NUP98HOXD13 + NUP98MECOM + RUNX1MKL1 + RBM15MLL + MLLT1MLL + MLLT4MLL + MLLT10MLL + PICALMMLLT10 + PICALMNCOA1 + PAX3NIN + PDGFRBNPM1 + RARANRG1 + ODZ4NTRK1 + TFGNUMA1 + RARANUP98 + PHF23PAX5 + ZNF521PBX1 + TCF3RET + TRIM27ROS1 + SLC34A2PML + RARAPRKAR1A + RARAPRKAR1A + RETRUNX1 + RUNX1T1RUNX1 + SH3D19	Cytoscape Web will replace the contents your graph	PPI Properties: Click on nodes or edges
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Statistics and Network structure information

Statistic of PPI Value(s) The number of interactors (fusion and proteins) 93 The number (and %) of the onco-proteins 29 (31.18 %) The number (and %) of the tumor suppressors 11 (11.83 %) Total number of binary PPIs (saturation %) 450 (10.52 %) The number (and %) of affected PPIs 91 (20.22 %) The number of possible different fusions 21 PPI diameter 5 PPI radius 3 The average degree of PPI 8.968 Assortativity coefficient -0.3249 The network average Clustering coefficient 0.410 The number (and %) of a zero Clustering coefficients 25 (26.88 %) The number (and %) of a zero Betweenness Centrality 28 (30.11 %)

ACTIVE INTERACTORS

List of the fusions
PPI for parental proteins: ZNF331,ACTA2	All fusions
Proteins found in more fusions	UBE3A (see 1 fusions); ERBB3 (see 2 fusions); CREBBP (see 6 fusions); LGALS3 (see 2 fusions); TPM1 (see 2 fusions); SMURF2 (see 1 fusions); EGFR (see 2 fusions); MCM2 (see 1 fusions); COPS5 (see 1 fusions); PTK2 (see 3 fusions); CUL1 (see 3 fusions); CUL3 (see 1 fusions); EP300 (see 1 fusions); LRRK2 (see 1 fusions); RPA1 (see 1 fusions); UBAP1 (see 1 fusions); ERRFI1 (see 1 fusions); PARK2 (see 1 fusions); KCNMA1 (see 2 fusions); TP53 (see 3 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	ZNF331	parental protein	9	0.083	300.428	KRAB (PF01352, IPR001909, SM00349): KRAB box zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Zn_ribbon_recom (PF13408, IPR025827): Recombinase zinc beta ribbon domain zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
2	ACTA2	parental protein	82	0.092	5551.992	Actin (PF00022, IPR004000, SM00268): Actin
3	AARS	interactor	1	0	0	DHHA1 (PF02272, IPR003156): DHHA1 domain Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal tRNA-synt_2c (PF01411, IPR018164): tRNA synthetases class II (A) tRNA_SAD (PF07973, IPR012947, SM00863): Threonyl and Alanyl tRNA synthetase second additional domain
4	ACTC1	interactor	7	0.286	13.379	Actin (PF00022, IPR004000, SM00268): Actin
5	ADRA1D	interactor	1	0	0	7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
6	ALOX12	oncoprotein	2	0	0	Lipoxygenase (PF00305, IPR013819): Lipoxygenase PLAT (PF01477, IPR001024, SM00308): PLAT/LH2 domain
7	ARAF	oncoprotein	4	1.000	0	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase RBD (PF02196, IPR003116, SM00455): Raf-like Ras-binding domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
8	C8orf33	interactor	6	0.400	120.144	DUF4615 (PF15393, IPR029274): Domain of unknown function (DUF4615)
9	CAND1	interactor	22	0.557	102.449	Adaptin_N (PF01602, IPR002553): Adaptin N terminal region DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981) HEAT (PF02985, IPR000357): HEAT repeat TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20) RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
10	CAPNS2	interactor	1	0	0	EF-hand_6 (PF13405, IPR002048): EF-hand domain EF-hand_7 (PF13499, IPR011992): EF-hand domain pair EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
11	CASQ2	interactor	1	0	0	Calsequestrin (PF01216, IPR001393): Calsequestrin SDA1 (PF05285, IPR007949): SDA1
12	CCT4	interactor	7	0.619	3.142	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
13	CCT5	interactor	5	0.700	0.736	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
14	CNN2	interactor	4	0.833	0.500	Calponin (PF00402, IPR000557): Calponin family repeat CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
15	COPS5	protein found in more fusions	21	0.611	36.047	JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
16	CREBBP	suppressor	7	0.600	93.687	Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain MAS20 (PF02064, IPR002056): MAS20 protein import receptor TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26 HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
17	CUL1	suppressor	22	0.448	62.713	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
18	CUL2	suppressor	15	0.600	26.115	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
19	CUL3	protein found in more fusions	30	0.330	296.536	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
20	CUL4B	oncoprotein	13	0.705	9.043	Cullin (PF00888, IPR001373, SM00182): Cullin family EBP50_C (PF09007, IPR015098): EBP50, C-terminal Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain PG_binding_4 (PF12229, IPR022029): Putative peptidoglycan binding domain MDFI (PF15316, IPR026134): MyoD family inhibitor
21	DHCR24	interactor	4	0.667	1.319	FAD_binding_4 (PF01565, IPR006094): FAD binding domain
22	DUSP19	interactor	1	0	0	DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
23	EGFR	oncoprotein	21	0.184	248.446	Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT) GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
24	EP300	oncoprotein	9	0.429	152.811	Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
25	ERBB3	oncoprotein	4	0.667	0.986	Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
26	ERRFI1	suppressor	6	0.600	2.371	GTPase_binding (PF09027, IPR015116): GTPase binding Inhibitor_Mig-6 (PF11555, IPR021619): EGFR receptor inhibitor Mig-6
27	FHL2	oncoprotein	7	0.333	323.547	LIM (PF00412, IPR001781, SM00132): LIM domain zf-ribbon_3 (PF13248): zinc-ribbon domain
28	FSCN1	oncoprotein	5	0.600	5.733	Fascin (PF06268, IPR022768): Fascin domain
29	GSTP1	suppressor	6	0.700	1.228	GST_N (PF02798, IPR004045): Glutathione S-transferase, N-terminal domain GST_C_3 (PF14497, IPR004046): Glutathione S-transferase, C-terminal domain
30	ICE2	interactor	1	0	0	NARG2_C (PF10505, IPR019535): NMDA receptor-regulated gene protein 2 C-terminus CLAMP (PF14769, IPR032727): Flagellar C1a complex subunit C1a-32
31	IPO8	interactor	4	0.167	95.206	BUD22 (PF09073, IPR015158): BUD22 Cse1 (PF08506, IPR013713): Cse1 HAND (PF09110, IPR015194): HAND IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein
32	KCNMA1	protein found in more fusions	2	0	0	BK_channel_a (PF03493, IPR003929): Calcium-activated BK potassium channel alpha subunit Ion_trans (PF00520, IPR005821): Ion transport protein TrkA_N (PF02254, IPR003148): TrkA-N domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein SUZ (PF12752, IPR024771): SUZ domain
33	LGALS3	oncoprotein	6	0.400	5.474	Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin
34	LRRK2	oncoprotein	8	0.571	4.533	Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain DUF1043 (PF06295, IPR009386): Protein of unknown function (DUF1043) T2SSE (PF00437, IPR001482): Type II/IV secretion system protein Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase Pkinase (PF00069, IPR000719): Protein kinase domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) PQQ_2 (PF13360, IPR002372): PQQ-like domain LRR_8 (PF13855, IPR001611): Leucine rich repeat COR (PF16095, IPR032171): C-terminal of Roc, COR, domain
35	LRRTM2	interactor	1	0	0	LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain LRR_8 (PF13855, IPR001611): Leucine rich repeat
36	MAP1LC3C	interactor	2	1.000	0	Atg8 (PF02991, IPR004241): Autophagy protein Atg8 ubiquitin like
37	MAPK6	oncoprotein	4	0	41.552	Pkinase (PF00069, IPR000719): Protein kinase domain
38	MCM2	oncoprotein	27	0.274	399.522	AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain
39	MRPL47	interactor	1	0	0	MRP-L47 (PF06984, IPR010729): Mitochondrial 39-S ribosomal protein L47 (MRP-L47)
40	MRPS2	interactor	4	0.667	2.385	Ribosomal_S2 (PF00318, IPR001865): Ribosomal protein S2
41	MRPS7	interactor	8	0.500	9.808	DUF454 (PF04304, IPR007401): Protein of unknown function (DUF454) Ribosomal_S7 (PF00177, IPR023798): Ribosomal protein S7p/S5e
42	MYH10	interactor	10	0.533	13.886	IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
43	MYH11	oncoprotein	7	0.476	7.179	IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
44	MYH9	suppressor	14	0.484	33.388	IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
45	MYO1C	interactor	10	0.667	11.354	IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_TH1 (PF06017, IPR010926): Unconventional myosin tail, actin- and lipid-binding Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
46	MYOC	interactor	5	0.500	2.333	IncA (PF04156, IPR007285): IncA protein OLF (PF02191, IPR003112, SM00284): Olfactomedin-like domain
47	NCF1	interactor	3	1.000	0	p47_phox_C (PF08944, IPR015039): NADPH oxidase subunit p47Phox, C terminal domain PX (PF00787, IPR001683, SM00312): PX domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain NECFESHC (PF16621, IPR032136): SH3 terminal domain of 2nd SH3 on Neutrophil cytosol factor 1
48	NOP56	interactor	14	0.780	34.375	Cytochrom_NNT (PF03264, IPR005126): NapC/NirT cytochrome c family, N-terminal region Nop (PF01798, IPR002687): snoRNA binding domain, fibrillarin NOP5NT (PF08156, IPR012974): NOP5NT (NUC127) domain RNA_polI_A34 (PF08208, IPR013240): DNA-directed RNA polymerase I subunit RPA34.5 SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
49	NR4A1	suppressor	3	0.333	32.309	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
50	PARK2	suppressor	10	0.389	12.237	IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
51	PCYT1B	interactor	1	0	0	ApoC-I (PF04691, IPR006781): Apolipoprotein C-I (ApoC-1) CTP_transf_like (PF01467, IPR004821): Cytidylyltransferase-like FTO_CTD (PF12934, IPR024366): FTO C-terminal domain
52	PECR	interactor	1	0	0	adh_short_C2 (PF13561): Enoyl-(Acyl carrier protein) reductase
53	PNMA1	oncoprotein	2	0	20.895	PNMA (PF14893, IPR026523): PNMA
54	PPP1R1A	oncoprotein	1	0	0	DARPP-32 (PF05395, IPR008466): Protein phosphatase inhibitor 1/DARPP-32
55	PRG2	interactor	1	0	0	Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain DUF4628 (PF15429, IPR027851): Domain of unknown function (DUF4628)
56	PTK2	protein found in more fusions	5	0.167	72.038	FERM_M (PF00373, IPR019748): FERM central domain Focal_AT (PF03623, IPR005189): Focal adhesion targeting region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase UCMA (PF17085, IPR031386): Unique cartilage matrix associated protein
57	RBM18	interactor	1	0	0	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
58	RPA1	suppressor	14	0.615	16.128	Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain
59	RPA2	oncoprotein	15	0.533	30.663	RPA_C (PF08784, IPR014892): Replication protein A C terminal tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2
60	RPA3	interactor	14	0.603	15.938	Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3
61	RPL10A	interactor	19	0.713	17.482	Ribosomal_L1 (PF00687, IPR028364): Ribosomal protein L1p/L10e family
62	RPL14	interactor	20	0.684	60.788	KOW (PF00467, IPR005824, SM00739): KOW motif Ribosomal_L14e (PF01929, IPR002784): Ribosomal protein L14 UPF0688 (PF15772, IPR031530): UPF0688 family
63	RPL17	interactor	17	0.728	15.808	Ribosomal_L22 (PF00237, IPR001063): Ribosomal protein L22p/L17e
64	RPL18	interactor	23	0.609	38.454	Ribosomal_L18 (PF17135): Ribosomal protein 60S L18 and 50S L18e
65	RPL7A	interactor	17	0.654	29.867	Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
66	RPS15A	interactor	21	0.605	45.111	Ribosomal_S8 (PF00410, IPR000630): Ribosomal protein S8
67	RPS16	interactor	21	0.671	25.750	Ribosomal_S9 (PF00380, IPR000754): Ribosomal protein S9/S16
68	RPS23	interactor	15	0.848	4.184	Ribosom_S12_S23 (PF00164, IPR006032): Ribosomal protein S12/S23
69	RPS26	interactor	14	0.791	10.733	Ribosomal_S26e (PF01283, IPR000892): Ribosomal protein S26e
70	RPS4X	interactor	20	0.726	15.176	KOW (PF00467, IPR005824, SM00739): KOW motif Ribosomal_S4e (PF00900, IPR013845): Ribosomal family S4e RS4NT (PF08071, IPR013843): RS4NT (NUC023) domain S4 (PF01479, IPR002942, SM00363): S4 domain 40S_S4_C (PF16121, IPR032277): 40S ribosomal protein S4 C-terminus
71	SELE	oncoprotein	2	0	27.950	EGF (PF00008, IPR000742, SM00181): EGF-like domain Sushi (PF00084, IPR000436, SM00032): Sushi repeat (SCR repeat) Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain
72	SHBG	oncoprotein	3	1.000	0	Laminin_G_1 (PF00054, IPR001791): Laminin G domain Laminin_G_2 (PF02210, IPR001791): Laminin G domain
73	SMURF2	protein found in more fusions	5	0.500	1.650	C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
74	SPTAN1	oncoprotein	11	0.509	108.202	EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand Spectrin (PF00435, IPR002017): Spectrin repeat SH3_1 (PF00018, IPR001452, SM00326): SH3 domain Tetrabrachion (PF11401, IPR021535): Tetrabrachion EF-hand_7 (PF13499, IPR011992): EF-hand domain pair E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain
75	SURF2	interactor	1	0	0	SURF2 (PF05477, IPR008833): Surfeit locus protein 2 (SURF2)
76	TFDP3	interactor	1	0	0	DP (PF08781, IPR014889, SM01138): Transcription factor DP E2F_TDP (PF02319, IPR003316): E2F/DP family winged-helix DNA-binding domain
77	THAP11	interactor	2	0	0	THAP (PF05485, IPR006612, SM00980): THAP domain DUF2722 (PF10846, IPR021216): Protein of unknown function (DUF2722) MRP-S31 (PF15433, IPR026299): Mitochondrial 28S ribosomal protein S31 FAM76 (PF16046, IPR032017): FAM76 protein
78	TP53	suppressor	28	0.236	387.333	DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
79	TPM1	protein found in more fusions	12	0.327	38.956	Tropomyosin (PF00261, IPR000533): Tropomyosin Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
80	TRIM9	interactor	4	0.667	1.000	fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain SPRY (PF00622, IPR003877, SM00449): SPRY domain DUF2203 (PF09969, IPR018699): Uncharacterized conserved protein (DUF2203) zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain Fer4_4 (PF12800, IPR001450): 4Fe-4S binding domain zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) CEBP_ZZ (PF16366, IPR032296): Cytoplasmic polyadenylation element-binding protein ZZ domain
81	UBAP1	protein found in more fusions	2	0	0	MerR-DNA-bind (PF09278, IPR015358): MerR, DNA binding UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain UPF0054 (PF02130, IPR002036): Uncharacterized protein family UPF0054
82	UBE3A	oncoprotein	8	0.333	90.060	HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) PCM1_C (PF15717, IPR031446): Pericentriolar material 1 C terminus AZUL (PF16558, IPR032353): Amino-terminal Zinc-binding domain of ubiquitin ligase E3A
83	UBL4A	interactor	13	0.513	26.231	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
84	UBXN4	interactor	1	0	0	Asp-B-Hydro_N (PF05279, IPR007943): Aspartyl beta-hydroxylase N-terminal region Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like UBX (PF00789, IPR001012, SM00166): UBX domain Thioredoxin_7 (PF13899): Thioredoxin-like
85	YBX1	oncoprotein	11	0.527	22.003	CSD (PF00313, IPR002059): 'Cold-shock' DNA-binding domain PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2
86	YIPF2	interactor	1	0	0	Yip1 (PF04893, IPR006977): Yip1 domain DUF4131 (PF13567, IPR025405): Domain of unknown function (DUF4131)
87	YWHAB	interactor	8	0.607	7.611	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein Virulence_fact (PF13769, IPR025989): Virulence factor
88	YWHAE	oncoprotein	16	0.258	135.416	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
89	YWHAQ	interactor	15	0.333	53.515	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
90	ZMAT3	interactor	1	0	0	zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding zf-met (PF12874): Zinc-finger of C2H2 type
91	ZNF212	interactor	4	1.000	0	KRAB (PF01352, IPR001909, SM00349): KRAB box zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-LYAR (PF08790, IPR014898): LYAR-type C2HC zinc finger DUF3669 (PF12417, IPR022137): Zinc finger protein zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
92	ZNF408	interactor	4	1.000	0	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
93	ZYX	suppressor	5	0.600	4.167	DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) LIM (PF00412, IPR001781, SM00132): LIM domain DUF2757 (PF10955, IPR020115): Protein of unknown function (DUF2757)

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