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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)111
The number (and %) of the onco-proteins30 (27.03 %)
The number (and %) of the tumor suppressors11 (9.91 %)
Total number of binary PPIs (saturation %)725 (11.88 %)
The number (and %) of affected PPIs109 (15.03 %)
The number of possible different fusions20
PPI diameter5
PPI radius3
The average degree of PPI12.270
Assortativity coefficient-0.0437
The network average Clustering coefficient0.539
The number (and %) of a zero Clustering coefficients7 (6.31 %)
The number (and %) of a zero Betweenness Centrality14 (12.61 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: SNX6,ZC3H13 All fusions
Proteins found in more fusions TSN (see 1 fusions); MED21 (see 1 fusions); U2AF2 (see 2 fusions); APEH (see 1 fusions); CSNK2A1/ELAVL1 (see 1 fusions); SRPK2 (see 1 fusions); ATP6V1C1 (see 3 fusions); IMPDH2 (see 2 fusions); NDEL1 (see 1 fusions); GAN (see 1 fusions); EGFR (see 2 fusions); SNX1 (see 1 fusions); POLR2A (see 2 fusions); CSNK2A1 (see 1 fusions); THOC1 (see 3 fusions); VPS35 (see 2 fusions); STAT1 (see 1 fusions); SUZ12 (see 2 fusions); CDK9 (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 SNX6parental protein550.0863948.661PX (PF00787, IPR001683, SM00312): PX domain
Vps5 (PF09325, IPR015404): Vps5 C terminal like
2 ZC3H13parental protein540.2422450.787FGF-BP1 (PF06473, IPR010510): FGF binding protein 1 (FGF-BP1)
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
PET117 (PF15786, IPR031568): PET assembly of cytochrome c oxidase, mitochondrial
3 ACVR2Binteractor40.6672.635Activin_recp (PF01064, IPR000472): Activin types I and II receptor domain
Pkinase (PF00069, IPR000719): Protein kinase domain
4 ACVRL1interactor30.3337.763Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif
5 ALYREFinteractor110.48938.878FYTT (PF07078, IPR009782): Forty-two-three protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
6 ANP32Einteractor50.9000.333BUD22 (PF09073, IPR015158): BUD22
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_9 (PF14580): Leucine-rich repeat
7 APEHoncoprotein61.0000Peptidase_S9 (PF00326, IPR001375): Prolyl oligopeptidase family
8 ATG7interactor80.7146.302ThiF (PF00899, IPR000594): ThiF family
ATG7_N (PF16420, IPR032197): Ubiquitin-like modifier-activating enzyme ATG7 N-terminus
9 ATP6V1C1protein found in more fusions140.57724.059V-ATPase_C (PF03223, IPR004907): V-ATPase subunit C
10 BAP1suppressor50.20045.248Peptidase_C12 (PF01088, IPR001578): Ubiquitin carboxyl-terminal hydrolase, family 1
TFIIIC_delta (PF12657, IPR024761): Transcription factor IIIC subunit delta N-term
11 BMI1oncoprotein140.218242.342zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
12 BMPR1Binteractor3039.723Activin_recp (PF01064, IPR000472): Activin types I and II receptor domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif
13 BRCA1suppressor140.205248.472BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT
14 BRMS1suppressor200Dynactin_p62 (PF05502, IPR008603): Dynactin p62 family
Sds3 (PF08598, IPR013907): Sds3-like
15 CALM1interactor110.255135.286EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
16 CAMKMTinteractor30.6670.803Methyltransf_16 (PF10294, IPR019410): Lysine methyltransferase
17 CBR1interactor30.33313.591adh_short (PF00106, IPR002198): short chain dehydrogenase
18 CCNCsuppressor230.93710.012Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
Cyclin_C_2 (PF16899, IPR031658): Cyclin C-terminal domain
19 CCNL2interactor40.33315.770Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
20 CDK19interactor230.9098.002Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
Pkinase (PF00069, IPR000719): Protein kinase domain
21 CDK9protein found in more fusions110.48930.339Pkinase (PF00069, IPR000719): Protein kinase domain
22 CENPAinteractor70.40051.026Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
23 CLK1interactor40.33317.425PDGF_N (PF04692, IPR006782): Platelet-derived growth factor, N terminal region
Pkinase (PF00069, IPR000719): Protein kinase domain
24 COILinteractor50.66710.182CDC45 (PF02724, IPR003874): CDC45-like protein
Macoilin (PF09726, IPR019130): Transmembrane protein
Coilin_N (PF15862, IPR031722): Coilin N-terminus
25 CSNK2A1oncoprotein100.25080.725Pkinase (PF00069, IPR000719): Protein kinase domain
26 CSNK2A2interactor120.242207.503Pkinase (PF00069, IPR000719): Protein kinase domain
27 DISC1interactor40.33333.390HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
Mnd1 (PF03962, IPR005647): Mnd1 family
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
Tropomyosin (PF00261, IPR000533): Tropomyosin
UVR (PF02151, IPR001943): UvrB/uvrC motif
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
28 DNM3interactor40.6677.239Dynamin_M (PF01031, IPR000375): Dynamin central region
GED (PF02212, IPR003130, SM00302): Dynamin GTPase effector domain
PH (PF00169, IPR001849, SM00233): PH domain
Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family
29 EGFRoncoprotein130.303211.473Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
30 EIF4A3interactor130.409104.711DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
31 ELAVL1oncoprotein260.167918.324RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
32 ESR1suppressor320.2921293.450Oest_recep (PF02159, IPR001292): Oestrogen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
33 FAM129Binteractor90.63910.520PH (PF00169, IPR001849, SM00233): PH domain
34 FAM221Ainteractor21.0000FAM221 (PF14753, IPR026755): Protein FAM221A/B
35 FAM43Ainteractor2017.730PID_2 (PF14719, IPR006020): Phosphotyrosine interaction domain (PTB/PID)
36 GANprotein found in more fusions200BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_3 (PF13415): Galactose oxidase, central domain
Kelch_5 (PF13854): Kelch motif
37 GATSinteractor21.0000ACT_7 (PF13840, IPR027795): ACT domain
38 GIT1interactor40.66712.737ArfGap (PF01412, IPR001164, SM00105): Putative GTPase activating protein for Arf
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
GIT_SHD (PF08518, IPR013724, SM00555): Spa2 homology domain (SHD) of GIT
GIT1_C (PF12205, IPR022018): G protein-coupled receptor kinase-interacting protein 1 C term
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
FlxA (PF14282, IPR025577): FlxA-like protein
GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor
39 GTF2A1oncoprotein60.46736.969TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
40 H3F3Aoncoprotein90.472156.281Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
41 HERC2interactor50.33311.370ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
Cyt-b5 (PF00173, IPR001199, SM01117): Cytochrome b5-like Heme/Steroid binding domain
MIB_HERC2 (PF06701, IPR010606): Mib_herc2
RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat
zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box)
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal
RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
42 ID1interactor21.0000HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
43 IFI16suppressor90.222123.622HIN (PF02760, IPR004021): HIN-200/IF120x domain
PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain
Mitofilin (PF09731, IPR019133): Mitochondrial inner membrane protein
44 IMPDH2protein found in more fusions70.267115.758IMPDH (PF00478, IPR001093): IMP dehydrogenase / GMP reductase domain
45 INSRinteractor40.8330.858fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
46 KIAA1429interactor110.32797.699Mpp10 (PF04006, IPR007151): Mpp10 protein
Sigma70_ner (PF04546, IPR007631): Sigma-70, non-essential region
INTS5_N (PF14837, IPR029445): Integrator complex subunit 5 N-terminus
VIR_N (PF15912, IPR031801): Virilizer, N-terminal
47 KIF26Binteractor31.0000Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
Microtub_bd (PF16796, IPR031852): Microtubule binding
48 KRASoncoprotein100.194355.932Ras (PF00071, IPR001806, SM00173): Ras family
49 LEPRoncoprotein40.8330.858fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Lep_receptor_Ig (PF06328, IPR010457): Ig-like C2-type domain
50 MAGOHinteractor80.50053.602Mago_nashi (PF02792, IPR004023): Mago nashi protein
51 MED1interactor300.74499.596Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
Med1 (PF10744, IPR019680): Mediator of RNA polymerase II transcription subunit 1
DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614)
PNISR (PF15996, IPR031937): Arginine/serine-rich protein PNISR
52 MED12oncoprotein280.74694.133Med12 (PF09497, IPR019035): Transcription mediator complex subunit Med12
Peptidase_S15 (PF02129, IPR000383): X-Pro dipeptidyl-peptidase (S15 family)
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19
DUF2877 (PF11392, IPR021530): Protein of unknown function (DUF2877)
Med12-PQL (PF12144, IPR021989): Eukaryotic Mediator 12 catenin-binding domain
Med12-LCEWAV (PF12145, IPR021990): Eukaryotic Mediator 12 subunit domain
CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
53 MED13oncoprotein240.92010.727Med13_C (PF06333, IPR009401): Mediator complex subunit 13 C-terminal
Med13_N (PF11597, IPR021643): Mediator complex subunit 13 N-terminal
54 MED14interactor240.9289.393Med14 (PF08638, IPR013947): Mediator complex subunit MED14
55 MED15interactor220.9700.756Med15 (PF09606, IPR019087): ARC105 or Med15 subunit of Mediator complex non-fungal
56 MED16interactor260.85251.257WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Med16 (PF11635, IPR021665): Mediator complex subunit 16
57 MED17oncoprotein270.80654.346Med17 (PF10156, IPR019313): Subunit 17 of Mediator complex
58 MED19interactor270.86211.045Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19
59 MED20interactor260.79769.105Med20 (PF08612, IPR013921): TATA-binding related factor (TRF) of subunit 20 of Mediator complex
60 MED21protein found in more fusions260.74781.441Med21 (PF11221, IPR021384): Subunit 21 of Mediator complex
61 MED23interactor290.739102.566Med23 (PF11573, IPR021629): Mediator complex subunit 23
62 MED24interactor250.92010.931Med24_N (PF11277, IPR021429): Mediator complex subunit 24 N-terminal
63 MED25interactor190.9545.579Med25 (PF11232, IPR021394): Mediator complex subunit 25 PTOV activation and synapsin 2
Med25_SD1 (PF11235, IPR021397): Mediator complex subunit 25 synapsin 1
Med25_NR-box (PF11244, IPR021406): Mediator complex subunit 25 C-terminal NR box-containing
Med25_VWA (PF11265, IPR021419): Mediator complex subunit 25 von Willebrand factor type A
64 MED26interactor270.81218.872Med26 (PF08711, IPR017923): TFIIS helical bundle-like domain
Med26_C (PF15693, IPR031416): Mediator complex subunit 26 C-terminal
Med26_M (PF15694, IPR031417): Mediator complex subunit 26 middle domain
65 MED27interactor230.9459.798Med27 (PF11571, IPR021627): Mediator complex subunit 27
66 MED28interactor300.719264.720cwf21 (PF08312, IPR013170, SM01115): cwf21 domain
Med28 (PF11594, IPR021640): Mediator complex subunit 28
67 MED29interactor270.86211.045Med29 (PF11568, IPR021018): Mediator complex subunit 29
68 MED30interactor230.9393.392Med30 (PF11315, IPR021019): Mediator complex subunit 30
69 MED4interactor320.593551.957Med4 (PF10018, IPR019258): Vitamin-D-receptor interacting Mediator subunit 4
70 MED6interactor270.80945.680Med6 (PF04934, IPR007018): MED6 mediator sub complex component
Peptidase_M15 (PF01427, IPR000755): D-ala-D-ala dipeptidase
71 MED8interactor230.9720.670Med8 (PF10232, IPR019364): Mediator of RNA polymerase II transcription complex subunit 8
72 MED9interactor260.84319.586Med9 (PF07544, IPR011425): RNA polymerase II transcription mediator complex subunit 9
73 MZT1interactor100Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif
MOZART1 (PF12554, IPR022214): Mitotic-spindle organizing gamma-tubulin ring associated
74 NDEL1protein found in more fusions40.33337.610HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
75 PAWRsuppressor100.68910.117ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
76 PCID2interactor60.5337.743PCI (PF01399, IPR000717, SM00088): PCI domain
77 PDGFRAoncoprotein80.57111.013Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Ig_3 (PF13927): Immunoglobulin domain
LAT (PF15234, IPR008359): Linker for activation of T-cells
78 PHLPP1suppressor30.66711.728LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
PH (PF00169, IPR001849, SM00233): PH domain
PP2C (PF00481, IPR001932): Protein phosphatase 2C
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
PRIMA1 (PF16101): Proline-rich membrane anchor 1
79 PIM1oncoprotein50.5007.586Pkinase (PF00069, IPR000719): Protein kinase domain
80 POLR2Aprotein found in more fusions230.459206.040RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1
RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2
RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3
RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4
RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5
RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat
81 POLR2Binteractor120.51549.888RNA_pol_Rpb2_1 (PF04563, IPR007644): RNA polymerase beta subunit
RNA_pol_Rpb2_3 (PF04565, IPR007645): RNA polymerase Rpb2, domain 3
RNA_pol_Rpb2_4 (PF04566, IPR007646): RNA polymerase Rpb2, domain 4
RNA_pol_Rpb2_5 (PF04567, IPR007647): RNA polymerase Rpb2, domain 5
RNA_pol_Rpb2_6 (PF00562, IPR007120): RNA polymerase Rpb2, domain 6
RNA_pol_Rpb2_7 (PF04560, IPR007641): RNA polymerase Rpb2, domain 7
82 RTF1interactor40.16732.902K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain
Plus-3 (PF03126, IPR004343): Plus-3 domain
V_ATPase_I (PF01496, IPR002490): V-type ATPase 116kDa subunit family
YL1 (PF05764, IPR008895): YL1 nuclear protein
AAA_23 (PF13476): AAA domain
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
IMUP (PF15761, IPR026621): Immortalisation up-regulated protein
83 SCHIP1interactor200SCHIP-1 (PF10148, IPR015649): Schwannomin-interacting protein 1
84 SHMT1interactor120.60018.808SHMT (PF00464, IPR001085): Serine hydroxymethyltransferase
85 SHMT2interactor150.314369.081SHMT (PF00464, IPR001085): Serine hydroxymethyltransferase
86 SIRT7interactor120.273162.601DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563)
SIR2 (PF02146, IPR003000): Sir2 family
87 SNX1protein found in more fusions160.333298.070PX (PF00787, IPR001683, SM00312): PX domain
Sorting_nexin (PF03700, IPR005329): Sorting nexin, N-terminal domain
Vps5 (PF09325, IPR015404): Vps5 C terminal like
88 SNX2interactor280.201524.252PX (PF00787, IPR001683, SM00312): PX domain
Sorting_nexin (PF03700, IPR005329): Sorting nexin, N-terminal domain
Vps5 (PF09325, IPR015404): Vps5 C terminal like
89 SNX4interactor60.6674.649PX (PF00787, IPR001683, SM00312): PX domain
Vps5 (PF09325, IPR015404): Vps5 C terminal like
90 SRPK2oncoprotein100.306137.860DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
Pkinase (PF00069, IPR000719): Protein kinase domain
S-antigen (PF05756, IPR008825): S-antigen protein
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
91 STAT1suppressor170.358145.891SH2 (PF00017, IPR000980, SM00252): SH2 domain
STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain
STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain
STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
STAT1_TAZ2bind (PF12162, IPR022752): STAT1 TAZ2 binding domain
92 SUZ12suppressor130.39449.552DUF2070 (PF09843, IPR019204): Predicted membrane protein (DUF2070)
VEFS-Box (PF09733, IPR019135): VEFS-Box of polycomb protein
93 TEAD4interactor100TEA (PF01285, IPR000818, SM00426): TEA/ATTS domain family
94 TERF2interactor110.244117.085Aconitase_C (PF00694, IPR000573): Aconitase C-terminal domain
TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF)
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
TERF2_RBM (PF16772, IPR031902): Telomeric repeat-binding factor 2 Rap1-binding motif
95 TGFBR1oncoprotein50.30081.378Activin_recp (PF01064, IPR000472): Activin types I and II receptor domain
Pkinase (PF00069, IPR000719): Protein kinase domain
TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif
96 TGFBR2suppressor40.5004.389ecTbetaR2 (PF08917, IPR015013): Transforming growth factor beta receptor 2 ectodomain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
97 THOC1protein found in more fusions50.8331.262Death (PF00531, IPR000488, SM00005): Death domain
efThoc1 (PF11957, IPR021861): THO complex subunit 1 transcription elongation factor
98 TNIKinteractor21.0000CNH (PF00780, IPR001180, SM00036): CNH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family
DUF3499 (PF12005, IPR021888): Protein of unknown function (DUF3499)
CNDH2_M (PF16869): PF16858
AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3
99 TREML2interactor21.0000Lamp (PF01299, IPR002000): Lysosome-associated membrane glycoprotein (Lamp)
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
100 TSNprotein found in more fusions100.444141.882Translin (PF01997, IPR002848): Translin family
101 TSNAXinteractor50.20087.685Translin (PF01997, IPR002848): Translin family
102 U2AF2protein found in more fusions170.275246.699RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Transformer (PF06495, IPR010519): Fruit fly transformer protein
103 USP15oncoprotein80.190154.379UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
DUSP (PF06337, IPR006615, SM00695): DUSP domain
Ubiquitin_3 (PF14836, IPR028135): Ubiquitin-like domain
104 USP46interactor30.6671.000UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
105 VAPBinteractor21.0000ATP-synt_G (PF04718, IPR006808): Mitochondrial ATP synthase g subunit
ZapB (PF06005, IPR009252): Cell division protein ZapB
Motile_Sperm (PF00635, IPR000535): MSP (Major sperm protein) domain
106 VPS29interactor110.69110.995Metallophos_2 (PF12850, IPR024654): Calcineurin-like phosphoesterase superfamily domain
107 VPS35protein found in more fusions120.49154.554FerA (PF08165, IPR012560): FerA (NUC095) domain
Vps35 (PF03635, IPR005378): Vacuolar protein sorting-associated protein 35
108 WBP11interactor40.6672.233BUD22 (PF09073, IPR015158): BUD22
Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
SspB (PF04386, IPR007481): Stringent starvation protein B
Wbp11 (PF09429, IPR019007): WW domain binding protein 11
ABC_trans_N (PF14510, IPR029481): ABC-transporter extracellular N-terminal
109 WTAPoncoprotein80.32172.063DUF1043 (PF06295, IPR009386): Protein of unknown function (DUF1043)
SOSSC (PF15925, IPR031821): SOSS complex subunit C
Wtap (PF17098, IPR029732): Pre-mRNA-splicing regulator WTAP
110 YWHAQinteractor100.267146.02114-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
111 ZNF645interactor31.0000HNH (PF01844, IPR002711): HNH endonuclease
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)

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