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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins SLC24A3, DDAH1 (from a repository: Sun May 7 20:24:19 2017)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)14
The number (and %) of the onco-proteins2 (14.29 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)26 (28.57 %)
The number (and %) of affected PPIs12 (46.15 %)
The number of possible different fusions2
PPI diameter2
PPI radiusinf
The average degree of PPI2.714
Assortativity coefficient-0.3842
The network average Clustering coefficient0.269
The number (and %) of a zero Clustering coefficients7 (50.00 %)
The number (and %) of a zero Betweenness Centrality7 (50.00 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: SLC24A3,DDAH1 All fusions
Proteins found in more fusions ATP5A1 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 SLC24A3interactor000CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
Na_Ca_ex (PF01699, IPR004837): Sodium/calcium exchanger protein
NOA36 (PF06524, IPR010531): NOA36 protein
SPC25 (PF06703, IPR009582): Microsomal signal peptidase 25 kDa subunit (SPC25)
DUF3040 (PF11239, IPR021401): Protein of unknown function (DUF3040)
2 DDAH1parental protein120.106109.333Amidinotransf (PF02274, IPR003198): Amidinotransferase
3 APOOLinteractor200ApoO (PF09769, IPR019166): Apolipoprotein O
4 ATP5A1protein found in more fusions50.5002.667ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain
ATP-synt_ab_C (PF00306, IPR000793): ATP synthase alpha/beta chain, C terminal domain
ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain
5 BOLA3interactor200BolA (PF01722, IPR002634): BolA-like protein
RNA_binding (PF01877, IPR002739): RNA binding
6 CALM1interactor40.5002.667EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
7 DDAH2interactor100Amidinotransf (PF02274, IPR003198): Amidinotransferase
8 ELAVL1oncoprotein40.6671.000RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
9 IQCB1interactor30.6671.000DUF1765 (PF08578, IPR013887): Protein of unknown function (DUF1765)
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
HJURP_C (PF12347, IPR022102): Holliday junction regulator protein family C-terminal repeat
Condensin2nSMC (PF12422, IPR024741): Condensin II non structural maintenance of chromosomes subunit
10 LACE1interactor200AFG1_ATPase (PF03969, IPR005654): AFG1-like ATPase
11 LYRM4interactor200Complex1_LYR (PF05347, IPR008011): Complex 1 protein (LYR family)
12 MOV10interactor30.6670.667AAA_12 (PF13087): AAA domain
AAA_30 (PF13604): AAA domain
13 NXF1interactor40.6670.667NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding
TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
14 PSMD10interactor100Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)

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