Find Fusion Network

Fusion ID:
Protein names:

Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins TWSG1, ZNF254 (from a repository: Sat Aug 3 00:55:59 2019)

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Force Directed
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)7
The number (and %) of the onco-proteins0 (0.00 %)
The number (and %) of the tumor suppressors1 (14.29 %)
Total number of binary PPIs (saturation %)5 (23.81 %)
The number (and %) of affected PPIs5 (100.00 %)
The number of possible different fusions1
PPI diameter2
PPI radiusinf
The average degree of PPI1.429
Assortativity coefficient0
The network average Clustering coefficient0.000
The number (and %) of a zero Clustering coefficients7 (100.00 %)
The number (and %) of a zero Betweenness Centrality6 (85.71 %)


List of the fusions

PPI for parental proteins: TWSG1,ZNF254 All fusions
Proteins found in more fusions

List of active interactors

# Name Type Number of PPI (degree) Clustering
Domains (Pfam, InterPro, SMART): description
1 TWSG1parental protein5020.000Tsg (PF04668, IPR006761): Twisted gastrulation (Tsg) protein conserved region
2 ZNF254interactor000KRAB (PF01352, IPR001909, SM00349): KRAB box
ROS_MUCR (PF05443, IPR008807): ROS/MUCR transcriptional regulator protein
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
LCE (PF14672, IPR028205): Late cornified envelope
zn-ribbon_14 (PF16503, IPR032442): Zinc-ribbon
3 BMP4suppressor100TGFb_propeptide (PF00688, IPR001111): TGF-beta propeptide
TGF_beta (PF00019, IPR001839, SM00204): Transforming growth factor beta like domain
4 CHRDinteractor100CHRD (PF07452, IPR010895, SM00754): CHRD domain
VWC (PF00093, IPR001007, SM00214): von Willebrand factor type C domain
5 MOV10interactor100AAA_12 (PF13087): AAA domain
AAA_30 (PF13604): AAA domain
6 SGTAinteractor100TOM20_plant (PF06552, IPR010547): Plant specific mitochondrial import receptor subunit TOM20
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
XPC-binding (PF09280, IPR015360): XPC-binding domain
TPR_17 (PF13431): Tetratricopeptide repeat
SGTA_dimer (PF16546, IPR032374): Homodimerisation domain of SGTA
7 TNS2interactor100PTB (PF08416, IPR013625): Phosphotyrosine-binding domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
PRIMA1 (PF16101): Proline-rich membrane anchor 1

B a c k    t o    T o p ⇑