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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins FRMD4B, GSDMC (from a repository: Sat Jun 29 18:39:57 2019)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)4
The number (and %) of the onco-proteins1 (25.00 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)4 (66.67 %)
The number (and %) of affected PPIs2 (50.00 %)
The number of possible different fusions1
PPI diameter3
PPI radius2
The average degree of PPI1.500
Assortativity coefficient0
The network average Clustering coefficient0.000
The number (and %) of a zero Clustering coefficients4 (100.00 %)
The number (and %) of a zero Betweenness Centrality2 (50.00 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: FRMD4B,GSDMC All fusions
Proteins found in more fusions

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 FRMD4Bparental protein100FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
Med30 (PF11315, IPR021019): Mediator complex subunit 30
DUF3338 (PF11819, IPR021774): Domain of unknown function (DUF3338)
2 GSDMCparental protein100Gasdermin (PF04598, IPR007677): Gasdermin family
3 KRASoncoprotein304.000Ras (PF00071, IPR001806, SM00173): Ras family
4 XPO1interactor204.000CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region

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