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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)203
The number (and %) of the onco-proteins54 (26.60 %)
The number (and %) of the tumor suppressors34 (16.75 %)
Total number of binary PPIs (saturation %)1427 (6.96 %)
The number (and %) of affected PPIs203 (14.23 %)
The number of possible different fusions35
PPI diameter4
PPI radius2
The average degree of PPI13.271
Assortativity coefficient-0.2726
The network average Clustering coefficient0.519
The number (and %) of a zero Clustering coefficients13 (6.40 %)
The number (and %) of a zero Betweenness Centrality35 (17.24 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: SKP1,PRIM2 All fusions
Proteins found in more fusions TUBG1 (see 1 fusions); GRK5 (see 4 fusions); KDM2B (see 1 fusions); CUL7 (see 2 fusions); CUL1 (see 3 fusions); CUL3 (see 1 fusions); MYC (see 2 fusions); AHCYL1 (see 3 fusions); PIP4K2B (see 3 fusions); COPS5 (see 1 fusions); PAK2 (see 2 fusions); UBC (see 1 fusions); CCND1 (see 1 fusions); NEDD4 (see 1 fusions); TP53 (see 3 fusions); SUZ12 (see 2 fusions); CUL4A (see 4 fusions); YWHAG (see 1 fusions); CRY2 (see 3 fusions); VCP (see 4 fusions); MED21 (see 1 fusions); HSP90AA1 (see 3 fusions); PRPS2 (see 2 fusions); FAF1 (see 2 fusions); BCOR (see 1 fusions); ETV6 (see 1 fusions); BAG3 (see 4 fusions); MCM2 (see 1 fusions); KDM1A (see 2 fusions); CDC37 (see 2 fusions); PML (see 4 fusions); TBL1X (see 2 fusions); SUV39H1 (see 1 fusions); CDK9 (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 SKP1parental protein1850.05921565.119Skp1 (PF01466, IPR016072, SM00512): Skp1 family, dimerisation domain
Skp1_POZ (PF03931, IPR016073): Skp1 family, tetramerisation domain
2 PRIM2parental protein180.203436.216DNA_primase_lrg (PF04104, IPR007238): Eukaryotic and archaeal DNA primase, large subunit
3 AHCYL1suppressor110.26737.010AdoHcyase (PF05221, IPR000043, SM00996): S-adenosyl-L-homocysteine hydrolase
AdoHcyase_NAD (PF00670, IPR015878, SM00997): S-adenosyl-L-homocysteine hydrolase, NAD binding domain
DUF515 (PF04415, IPR007509): Protein of unknown function (DUF515)
Big_3_5 (PF16640, IPR032109): Bacterial Ig-like domain (group 3)
4 ANKRD36BP1interactor100NA
5 APIPinteractor41.0000Aldolase_II (PF00596, IPR001303, SM01007): Class II Aldolase and Adducin N-terminal domain
6 ARID1Asuppressor100.51113.687ARID (PF01388, IPR001606, SM00501): ARID/BRIGHT DNA binding domain
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
TAF4 (PF05236, IPR007900): Transcription initiation factor TFIID component TAF4 family
YscJ_FliF_C (PF08345, IPR013556): Flagellar M-ring protein C-terminal
TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence
BAF250_C (PF12031, IPR021906): SWI/SNF-like complex subunit BAF250/Osa
Keratin_2_tail (PF16210, IPR032449): Keratin type II cytoskeletal 1 tail
7 ATP6V1B2interactor50.5006.068ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain
ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain
DUF2481 (PF10654, IPR018916): Protein of unknown function (DUF2481)
8 AURKAoncoprotein180.29449.926Pkinase (PF00069, IPR000719): Protein kinase domain
MTBP_C (PF14920, IPR029418): MDM2-binding
9 BAG3oncoprotein110.31199.774BAG (PF02179, IPR003103, SM00264): BAG domain
WW (PF00397, IPR001202, SM00456): WW domain
10 BAG6interactor110.22262.664DUF1179 (PF06678, IPR009564): Protein of unknown function (DUF1179)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
DUF2939 (PF11159, IPR021330): Protein of unknown function (DUF2939)
DUF3538 (PF12057, IPR021925): Domain of unknown function (DUF3538)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
11 BCORoncoprotein100.5568.623Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
BCOR (PF15808, IPR031628): BCL-6 co-repressor, non-ankyrin-repeat region
PUFD (PF16553, IPR032365): BCORL-PCGF1-binding domain
12 BORAinteractor50.7000.384BORA_N (PF15280, IPR023252): Protein aurora borealis N-terminus
13 BRCA1suppressor320.245195.141BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT
14 BTG1oncoprotein90.4728.086BTG (PF07742, IPR002087, SM00099): BTG family
15 BTG2suppressor70.6192.532BTG (PF07742, IPR002087, SM00099): BTG family
16 BTRConcoprotein480.209476.850WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
17 CACYBPinteractor70.6004.335CS (PF04969, IPR007052): CS domain
SGS (PF05002, IPR007699): SGS domain
Siah-Interact_N (PF09032, IPR015120): Siah interacting protein, N terminal
18 CAND1interactor240.43183.374Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981)
HEAT (PF02985, IPR000357): HEAT repeat
TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20)
RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
19 CCDC22interactor40.8330.100DUF812 (PF05667, IPR008530): Protein of unknown function (DUF812)
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
Hrs_helical (PF12210, IPR024641): Hepatocyte growth factor-regulated tyrosine kinase substrate
20 CCDC6oncoprotein60.6672.331CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
DUF2046 (PF09755, IPR019152): Uncharacterized conserved protein H4 (DUF2046)
FAM199X (PF15814, IPR029672): Protein family FAM199X
21 CCNA2oncoprotein200.49182.875Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
Cyclin_N2 (PF16500, IPR032447): N-terminal region of cyclin_N
22 CCND1oncoprotein210.42146.943Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
23 CCNFoncoprotein31.0000Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
Sel1 (PF08238, IPR006597, SM00671): Sel1 repeat
F-box (PF00646, IPR001810, SM00256): F-box domain
24 CCNG2interactor21.0000Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
25 CDC25Aoncoprotein80.6078.235M-inducer_phosp (PF06617, IPR000751): M-phase inducer phosphatase
Rhodanese (PF00581, IPR001763, SM00450): Rhodanese-like domain
26 CDC37protein found in more fusions200.216109.911CDC37_C (PF08564, IPR013873, SM01069): Cdc37 C terminal domain
CDC37_M (PF08565, IPR013874, SM01070): Cdc37 Hsp90 binding domain
CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding
Rho_Binding (PF08912, IPR015008): Rho Binding
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
27 CDCA3interactor40.5002.019NA
28 CDH2interactor60.5334.707Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region
Cadherin_pro (PF08758, IPR014868, SM01055): Cadherin prodomain like
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain
Cadherin_3 (PF16184): Cadherin-like
29 CDK2suppressor380.321265.169Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
30 CDK3interactor110.9450.446Pkinase (PF00069, IPR000719): Protein kinase domain
31 CDK4oncoprotein200.44769.145Pkinase (PF00069, IPR000719): Protein kinase domain
32 CDK9protein found in more fusions120.5829.743Pkinase (PF00069, IPR000719): Protein kinase domain
33 CDKN1Asuppressor250.363144.532CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor
34 CDKN1Bsuppressor210.52936.786CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor
Multi-haem_cyto (PF13447): Seven times multi-haem cytochrome CxxCH
35 CENPEinteractor41.0000bZIP_1 (PF00170, IPR004827): bZIP transcription factor
VIT1 (PF01988, IPR008217): VIT family
DUF1515 (PF07439, IPR010889): Protein of unknown function (DUF1515)
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
ZapB (PF06005, IPR009252): Cell division protein ZapB
Fez1 (PF06818): Fez1
FUSC (PF04632, IPR006726): Fusaric acid resistance protein family
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
IncA (PF04156, IPR007285): IncA protein
NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein
OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Pepsin-I3 (PF06394, IPR010480): Pepsin inhibitor-3-like repeated domain
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
SlyX (PF04102, IPR007236): SlyX
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
TrbI_Ftype (PF09677, IPR014115): Type-F conjugative transfer system protein (TrbI_Ftype)
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
AAA_13 (PF13166, IPR026866): AAA domain
DUF4023 (PF13215, IPR025097): Protein of unknown function (DUF4023)
HAUS6_N (PF14661, IPR028163): HAUS augmin-like complex subunit 6 N-terminus
UPF0449 (PF15136, IPR028227): Uncharacterised protein family UPF0449
HMMR_N (PF15905, IPR031787): Hyaluronan mediated motility receptor N-terminal
T3SSipB (PF16535, IPR032391): Type III cell invasion protein SipB
36 CIAO1interactor60.8671.187WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
37 CKS1Boncoprotein130.8184.254CKS (PF01111, IPR000789, SM01084): Cyclin-dependent kinase regulatory subunit
38 COPS3interactor210.60025.603RasGEF (PF00617, IPR001895, SM00147): RasGEF domain
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
PCI (PF01399, IPR000717, SM00088): PCI domain
39 COPS4interactor220.54547.034DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
PCI (PF01399, IPR000717, SM00088): PCI domain
TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_14 (PF13428): Tetratricopeptide repeat
40 COPS5protein found in more fusions500.283438.623JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
41 COPS6interactor440.276684.626DUF320 (PF03777, IPR005528): Small secreted domain (DUF320)
JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function
42 CORO1Concoprotein80.60711.575DUF1899 (PF08953, IPR015048, SM01166): Domain of unknown function (DUF1899)
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
WD40_4 (PF16300): Type of WD40 repeat
43 CRY1interactor80.57127.703DNA_photolyase (PF00875, IPR006050): DNA photolyase
FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase
44 CRY2protein found in more fusions130.54513.673DNA_photolyase (PF00875, IPR006050): DNA photolyase
FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase
45 CTNNB1oncoprotein300.251249.655Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361)
HEAT_EZ (PF13513): HEAT-like repeat
46 CUL1suppressor1160.1014761.477Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
47 CUL3protein found in more fusions410.291481.120Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
48 CUL4Aprotein found in more fusions370.354165.773Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
49 CUL5suppressor250.50072.415Cullin (PF00888, IPR001373, SM00182): Cullin family
GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
50 CUL7protein found in more fusions210.274118.091ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
Cullin (PF00888, IPR001373, SM00182): Cullin family
DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918)
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
51 DAB2IPsuppressor70.6191.921C2 (PF00168, IPR000008, SM00239): C2 domain
PH_2 (PF08458, IPR013666): Plant pleckstrin homology-like region
RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase
DUF3498 (PF12004, IPR021887): Domain of unknown function (DUF3498)
52 EEDsuppressor190.31481.470WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
53 EEF2Kinteractor50.7007.563Alpha_kinase (PF02816, IPR004166, SM00811): Alpha-kinase family
Sel1 (PF08238, IPR006597, SM00671): Sel1 repeat
54 ELAVL1oncoprotein590.1361729.989RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
55 ESR1suppressor340.269380.084Oest_recep (PF02159, IPR001292): Oestrogen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
56 ETV6suppressor40.6672.248Ets (PF00178, IPR000418, SM00413): Ets-domain
SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain
57 FAF1protein found in more fusions140.56442.862UBX (PF00789, IPR001012, SM00166): UBX domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
AAA_11 (PF13086): AAA domain
UBA_4 (PF14555): UBA-like domain
58 FAM96Binteractor70.38143.778DUF59 (PF01883, IPR002744): Domain of unknown function DUF59
59 FBXL12interactor60.7330.924F-box-like (PF12937, IPR001810): F-box-like
60 FBXL15interactor60.8000.735LRV (PF01816, IPR004830): Leucine rich repeat variant
F-box (PF00646, IPR001810, SM00256): F-box domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
61 FBXL17interactor40.66736.172TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
F-box-like (PF12937, IPR001810): F-box-like
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
62 FBXL19interactor100AF-4 (PF05110, IPR007797): AF-4 proto-oncoprotein
LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain
F-box (PF00646, IPR001810, SM00256): F-box domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
RbpA (PF13397, IPR025182): RNA polymerase-binding protein
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
LRR_8 (PF13855, IPR001611): Leucine rich repeat
PHD_4 (PF16866, IPR019787): PHD-finger
63 FBXL2interactor40.6670.347Ste50p-SAM (PF09235, IPR015316): Ste50p, sterile alpha motif
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
F-box-like (PF12937, IPR001810): F-box-like
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
64 FBXL21interactor41.0000NA
65 FBXL22interactor21.0000F-box-like (PF12937, IPR001810): F-box-like
66 FBXL3interactor80.6074.541F-box-like (PF12937, IPR001810): F-box-like
DUF4116 (PF13475, IPR025197): Domain of unknown function (DUF4116)
67 FBXL4interactor100Adeno_E3_CR2 (PF02439, IPR003470): Adenovirus E3 region protein CR2
LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
F-box (PF00646, IPR001810, SM00256): F-box domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
LRR_8 (PF13855, IPR001611): Leucine rich repeat
LRR_9 (PF14580): Leucine-rich repeat
68 FBXL5interactor90.393127.148Hemerythrin (PF01814, IPR012312): Hemerythrin HHE cation binding domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
F-box-like (PF12937, IPR001810): F-box-like
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
69 FBXL6interactor30.6670.833LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
F-box-like (PF12937, IPR001810): F-box-like
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
70 FBXL7oncoprotein30.6670.667LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
F-box-like (PF12937, IPR001810): F-box-like
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
71 FBXL8interactor31.0000LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
F-box-like (PF12937, IPR001810): F-box-like
72 FBXO11oncoprotein80.7502.089TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box)
F-box-like (PF12937, IPR001810): F-box-like
Beta_helix (PF13229): Right handed beta helix region
73 FBXO17interactor100.8442.368FBA (PF04300, IPR007397): F-box associated region
F-box-like (PF12937, IPR001810): F-box-like
74 FBXO18interactor50.9000.071F-box-like (PF12937, IPR001810): F-box-like
AAA_19 (PF13245): AAA domain
UvrD_C (PF13361, IPR014017): UvrD-like helicase C-terminal domain
AAA_30 (PF13604): AAA domain
75 FBXO2interactor80.46410.044FBA (PF04300, IPR007397): F-box associated region
F-box (PF00646, IPR001810, SM00256): F-box domain
76 FBXO21interactor90.6394.803YccV-like (PF08755, IPR011722, SM00992): Hemimethylated DNA-binding protein YccV like
F-box-like (PF12937, IPR001810): F-box-like
Transglut_core2 (PF13369, IPR032698): Transglutaminase-like superfamily
77 FBXO22interactor60.8002.803FIST (PF08495, IPR013702, SM00897): FIST N domain
FIST_C (PF10442, IPR019494): FIST C domain
F-box (PF00646, IPR001810, SM00256): F-box domain
78 FBXO24interactor31.0000RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat
F-box-like (PF12937, IPR001810): F-box-like
RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
SUKH-3 (PF14433, IPR025850): SUKH-3 immunity protein
79 FBXO25suppressor110.34526.881Elongin_A (PF06881, IPR010684): RNA polymerase II transcription factor SIII (Elongin) subunit A
80 FBXO27interactor50.8000.183FBA (PF04300, IPR007397): F-box associated region
F-box (PF00646, IPR001810, SM00256): F-box domain
81 FBXO28interactor50.5003.867Exonuc_VII_L (PF02601, IPR020579): Exonuclease VII, large subunit
F-box (PF00646, IPR001810, SM00256): F-box domain
FAM76 (PF16046, IPR032017): FAM76 protein
82 FBXO3interactor90.6943.138DUF525 (PF04379, IPR007474): ApaG domain
Elongin_A (PF06881, IPR010684): RNA polymerase II transcription factor SIII (Elongin) subunit A
SMI1_KNR4 (PF09346, IPR018958, SM00860): SMI1 / KNR4 family (SUKH-1)
F-box-like (PF12937, IPR001810): F-box-like
PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
83 FBXO30interactor50.4006.508zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger
zf-C2H2_4 (PF13894): C2H2-type zinc finger
DUF4644 (PF15486, IPR027978): Domain of unknown function (DUF4644)
zf-TRAF_2 (PF15965, IPR001293): TRAF-like zinc-finger
F-box_4 (PF15966, IPR001810): F-box
84 FBXO31suppressor60.8000.868DUF3506 (PF12014, IPR021894): Domain of unknown function (DUF3506)
F-box-like (PF12937, IPR001810): F-box-like
85 FBXO32suppressor30.6670.500Elongin_A (PF06881, IPR010684): RNA polymerase II transcription factor SIII (Elongin) subunit A
86 FBXO34interactor31.0000BTK (PF00779, IPR001562, SM00107): BTK motif
F-box-like (PF12937, IPR001810): F-box-like
87 FBXO36interactor100F-box (PF00646, IPR001810, SM00256): F-box domain
88 FBXO4interactor100.6114.582Arf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family
Elongin_A (PF06881, IPR010684): RNA polymerase II transcription factor SIII (Elongin) subunit A
F-box (PF00646, IPR001810, SM00256): F-box domain
89 FBXO42interactor50.8000.168Kelch_2 (PF07646, IPR011498): Kelch motif
F-box-like (PF12937, IPR001810): F-box-like
Kelch_3 (PF13415): Galactose oxidase, central domain
Kelch_4 (PF13418): Galactose oxidase, central domain
90 FBXO44interactor70.7621.050FBA (PF04300, IPR007397): F-box associated region
F-box-like (PF12937, IPR001810): F-box-like
91 FBXO45interactor70.38111.186SPRY (PF00622, IPR003877, SM00449): SPRY domain
F-box-like (PF12937, IPR001810): F-box-like
92 FBXO46interactor31.0000BTK (PF00779, IPR001562, SM00107): BTK motif
CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
CHORD (PF04968, IPR007051): CHORD
DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
F-box-like (PF12937, IPR001810): F-box-like
93 FBXO5oncoprotein60.6004.900IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
F-box (PF00646, IPR001810, SM00256): F-box domain
94 FBXO6interactor180.47130.519FBA (PF04300, IPR007397): F-box associated region
F-box-like (PF12937, IPR001810): F-box-like
95 FBXO7interactor60.8001.705Elongin_A (PF06881, IPR010684): RNA polymerase II transcription factor SIII (Elongin) subunit A
PI31_Prot_N (PF11566, IPR021625): PI31 proteasome regulator N-terminal
F-box-like (PF12937, IPR001810): F-box-like
96 FBXO8interactor41.0000Sec7 (PF01369, IPR000904, SM00222): Sec7 domain
F-box-like (PF12937, IPR001810): F-box-like
97 FBXO9interactor50.60091.678MIT (PF04212, IPR007330, SM00745): MIT (microtubule interacting and transport) domain
DUF3408 (PF11888, IPR021823): Protein of unknown function (DUF3408)
F-box-like (PF12937, IPR001810): F-box-like
98 FBXW11interactor370.222328.727WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
99 FBXW12interactor100F-box-like (PF12937, IPR001810): F-box-like
100 FBXW2interactor110.45514.898WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
101 FBXW4oncoprotein90.6673.652WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
F-box-like (PF12937, IPR001810): F-box-like
F-box_4 (PF15966, IPR001810): F-box
102 FBXW4P1interactor100NA
103 FBXW5interactor51.0000WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
F-box-like (PF12937, IPR001810): F-box-like
104 FBXW7suppressor280.205212.823Mem_trans (PF03547, IPR004776): Membrane transport protein
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
F-box-like (PF12937, IPR001810): F-box-like
105 FBXW8interactor150.55218.672WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
106 FBXW9interactor41.0000WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
F-box-like (PF12937, IPR001810): F-box-like
PQQ_3 (PF13570): PQQ-like domain
WD40_like (PF17005, IPR031544): WD40-like domain
107 FKBP2interactor2013.080FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase
108 FOXN2interactor50.8000.438Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
109 GATA2oncoprotein80.50014.418GATA (PF00320, IPR000679, SM00401): GATA zinc finger
110 GCM1interactor31.0000DUF1272 (PF06906, IPR010696): Protein of unknown function (DUF1272)
GCM (PF03615, IPR003902): GCM motif protein
111 GFOD1interactor40.3337.878GFO_IDH_MocA (PF01408, IPR000683): Oxidoreductase family, NAD-binding Rossmann fold
GFO_IDH_MocA_C (PF02894, IPR004104): Oxidoreductase family, C-terminal alpha/beta domain
112 GHRoncoprotein90.7861.947EpoR_lig-bind (PF09067, IPR015152): Erythropoietin receptor, ligand binding
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
GHBP (PF12772, IPR025871): Growth hormone receptor binding
113 GJB2suppressor21.0000Connexin (PF00029, IPR013092, SM00037): Connexin
114 GLMNoncoprotein80.6073.176Kinetochor_Ybp2 (PF08568, IPR013877): Uncharacterised protein family, YAP/Alf4/glomulin
115 GPS1interactor170.67612.909RPN7 (PF10602, IPR019585): 26S proteasome subunit RPN7
PCI (PF01399, IPR000717, SM00088): PCI domain
116 GRK5protein found in more fusions110.31154.660Pkinase (PF00069, IPR000719): Protein kinase domain
RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
117 HEY1oncoprotein30.6671.821Hairy_orange (PF07527, IPR003650): Hairy Orange
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
HTH_Crp_2 (PF13545, IPR012318): Crp-like helix-turn-helix domain
118 HSP90AA1oncoprotein640.1691112.021HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
119 IQCB1interactor70.5244.166DUF1765 (PF08578, IPR013887): Protein of unknown function (DUF1765)
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
HJURP_C (PF12347, IPR022102): Holliday junction regulator protein family C-terminal repeat
Condensin2nSMC (PF12422, IPR024741): Condensin II non structural maintenance of chromosomes subunit
120 KCTD9interactor41.0000BTB_2 (PF02214, IPR003131): BTB/POZ domain
Pentapeptide (PF00805, IPR001646): Pentapeptide repeats (8 copies)
KHA (PF11834, IPR021789): KHA, dimerisation domain of potassium ion channel
121 KDM1Aprotein found in more fusions120.30940.400Amino_oxidase (PF01593, IPR002937): Flavin containing amine oxidoreductase
CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
SWIRM (PF04433, IPR007526): SWIRM domain
DUF4298 (PF14131, IPR025384): Domain of unknown function (DUF4298)
122 KDM2Ainteractor31.0000JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain
F-box (PF00646, IPR001810, SM00256): F-box domain
DZR (PF12773, IPR025874): Double zinc ribbon
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
LRR_8 (PF13855, IPR001611): Leucine rich repeat
PHD_4 (PF16866, IPR019787): PHD-finger
123 KDM2Boncoprotein100.5568.530zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain
F-box (PF00646, IPR001810, SM00256): F-box domain
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
Cupin_8 (PF13621): Cupin-like domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
MRI (PF15325, IPR028278): Modulator of retrovirus infection
PHD_4 (PF16866, IPR019787): PHD-finger
124 KLC1interactor30.6670.948Gly_radical (PF01228, IPR001150): Glycine radical
SOGA (PF11365, IPR027881): Protein SOGA
TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat
TPR_12 (PF13424): Tetratricopeptide repeat
JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II
125 KLF4suppressor40.6671.167zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
126 KLHL20interactor80.23830.877BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
127 LATS2suppressor130.37918.854Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
128 LMO2oncoprotein50.5002.000CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
LIM (PF00412, IPR001781, SM00132): LIM domain
129 MAGEA11interactor200MAGE (PF01454, IPR002190): MAGE family
MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal
130 MAGEC2interactor41.0000MAGE (PF01454, IPR002190): MAGE family
MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal
APOC4 (PF15119, IPR028120): Apolipoprotein C4
131 MAP4K1suppressor80.7141.293CNH (PF00780, IPR001180, SM00036): CNH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
132 MCFD2interactor21.0000EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
133 MCM2oncoprotein210.300251.096AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
134 MED21protein found in more fusions90.5717.095Med21 (PF11221, IPR021384): Subunit 21 of Mediator complex
135 MED6interactor70.476228.777Med6 (PF04934, IPR007018): MED6 mediator sub complex component
Peptidase_M15 (PF01427, IPR000755): D-ala-D-ala dipeptidase
136 MMS19interactor140.264252.571DUF3437 (PF11919, IPR021843): Domain of unknown function (DUF3437)
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
HEAT_2 (PF13646): HEAT repeats
MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
137 MOV10interactor230.198229.798AAA_12 (PF13087): AAA domain
AAA_30 (PF13604): AAA domain
138 MTSS1suppressor51.0000IMD (PF08397, IPR013606): IRSp53/MIM homology domain
RAP1 (PF07218, IPR009864): Rhoptry-associated protein 1 (RAP-1)
WH2 (PF02205, IPR003124, SM00246): WH2 motif
MRI (PF15325, IPR028278): Modulator of retrovirus infection
139 MYConcoprotein340.277405.681HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain
Myc_N (PF01056, IPR012682): Myc amino-terminal region
140 NABP2interactor60.6672.559tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
141 NEDD4suppressor140.43618.572Rota_NS26 (PF01525, IPR002512): Rotavirus NS26
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
142 NEDD8interactor230.53733.204ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
143 NFKBIAoncoprotein130.46213.548Ank (PF00023, IPR002110, SM00248): Ankyrin repeat
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
144 NOS2interactor90.5006.821FAD_binding_1 (PF00667, IPR003097): FAD binding domain
Flavodoxin_1 (PF00258, IPR008254): Flavodoxin
NAD_binding_1 (PF00175, IPR001433): Oxidoreductase NAD-binding domain
NO_synthase (PF02898, IPR004030): Nitric oxide synthase, oxygenase domain
145 NTRK1oncoprotein460.194770.913I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
146 NUAK1suppressor80.60710.291Pkinase (PF00069, IPR000719): Protein kinase domain
147 NUDT9P1interactor100NA
148 PAK2protein found in more fusions70.6006.271PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain
Pkinase (PF00069, IPR000719): Protein kinase domain
149 PCGF1interactor100.6116.694zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
150 PCK1interactor60.40019.773PEPCK (PF00821, IPR008209): Phosphoenolpyruvate carboxykinase
151 PIP4K2Ainteractor21.0000PIP5K (PF01504, IPR002498): Phosphatidylinositol-4-phosphate 5-Kinase
152 PIP4K2Bprotein found in more fusions200PIP5K (PF01504, IPR002498): Phosphatidylinositol-4-phosphate 5-Kinase
153 PIP4K2Cinteractor40.6670.867PIP5K (PF01504, IPR002498): Phosphatidylinositol-4-phosphate 5-Kinase
154 PMLsuppressor160.32495.102zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
DUF3583 (PF12126, IPR021978): Protein of unknown function (DUF3583)
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
155 POLA1interactor140.363256.704DNA_pol_B (PF00136, IPR006134): DNA polymerase family B
DNA_pol_B_exo1 (PF03104, IPR006133): DNA polymerase family B, exonuclease domain
zf-DNA_Pol (PF08996, IPR015088): DNA Polymerase alpha zinc finger
DNA_pol_alpha_N (PF12254, IPR024647): DNA polymerase alpha subunit p180 N terminal
156 POLA2interactor60.8674.123DNA_pol_E_B (PF04042, IPR007185): DNA polymerase alpha/epsilon subunit B
Pol_alpha_B_N (PF08418, IPR013627): DNA polymerase alpha subunit B N-terminal
157 PPARGC1Ainteractor70.5713.483Pap_E4 (PF02711, IPR003861): E4 protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RSRP (PF17069): Arginine/Serine-Rich protein 1
158 PPP1CAsuppressor170.42628.513Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
159 PPP1CConcoprotein170.441162.951Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
160 PPP1R12Binteractor30.6670.867Mem_trans (PF03547, IPR004776): Membrane transport protein
SAE2 (PF08573, IPR013882): DNA repair protein endonuclease SAE2/CtIP C-terminus
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
161 PRIM1interactor110.418121.276DNA_primase_S (PF01896, IPR002755): DNA primase small subunit
162 PRPS2protein found in more fusions40.3338.536Pribosyltran (PF00156, IPR000836): Phosphoribosyl transferase domain
Pribosyltran_N (PF13793, IPR029099): N-terminal domain of ribose phosphate pyrophosphokinase
Pribosyl_synth (PF14572, IPR005946): Phosphoribosyl synthetase-associated domain
163 PSMA2interactor180.30151.750Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
164 PTENsuppressor140.34170.364DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein
165 RAE1interactor150.257301.209Exonuc_X-T_C (PF08411, IPR013620): Exonuclease C-terminal
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
166 RASSF1suppressor120.40066.197RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
Nore1-SARAH (PF16517, IPR011524): Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain
167 RBL2suppressor120.56143.517CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Pap_E4 (PF02711, IPR003861): E4 protein
RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain
RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain
SLH (PF00395, IPR001119): S-layer homology domain
TFIIB (PF00382, IPR013150): Transcription factor TFIIB repeat
DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452)
168 RBX1oncoprotein580.183743.154zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain
169 RFWD2suppressor140.7315.419Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein
IncA (PF04156, IPR007285): IncA protein
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
WD40_like (PF17005, IPR031544): WD40-like domain
170 RNF2interactor220.271181.423zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
171 RYBPinteractor80.7145.943DUF11 (PF01345, IPR001434): Domain of unknown function DUF11
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase (PF00069, IPR000719): Protein kinase domain
PPAK (PF02818, IPR004168): PPAK motif
Titin_Z (PF09042, IPR015129): Titin Z
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Y_Y_Y (PF07495, IPR011123): Y_Y_Y domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
Ig_3 (PF13927): Immunoglobulin domain
172 SCNN1Dinteractor21.0000ASC (PF00858, IPR001873): Amiloride-sensitive sodium channel
PRIMA1 (PF16101): Proline-rich membrane anchor 1
173 SF3B3interactor160.48319.708CPSF_A (PF03178, IPR004871): CPSF A subunit region
MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term
174 SKP2suppressor320.343171.983LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
LRR_2 (PF07723, IPR013101): Leucine Rich Repeat
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
F-box-like (PF12937, IPR001810): F-box-like
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
LRR_8 (PF13855, IPR001611): Leucine rich repeat
175 SNRNP70interactor160.49219.155RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
176 SSU72interactor100Ssu72 (PF04722, IPR006811): Ssu72-like protein
177 STN1interactor40.50010.372STN1_2 (PF09170, IPR015253): CST, Suppressor of cdc thirteen homolog, complex subunit STN1
RUN (PF02759, IPR004012, SM00593): RUN domain
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
Stn1 (PF10451, IPR018856): Telomere regulation protein Stn1
178 SUGT1interactor80.46410.096CheC (PF04509, IPR007597): CheC-like family
CS (PF04969, IPR007052): CS domain
SGS (PF05002, IPR007699): SGS domain
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
179 SUV39H1protein found in more fusions100.25033.536Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
Pre-SET (PF05033, IPR007728): Pre-SET motif
SET (PF00856, IPR001214, SM00317): SET domain
180 SUZ12suppressor150.38529.228DUF2070 (PF09843, IPR019204): Predicted membrane protein (DUF2070)
VEFS-Box (PF09733, IPR019135): VEFS-Box of polycomb protein
181 TBK1interactor130.40920.250DUF713 (PF05218, IPR007883): Protein of unknown function (DUF713)
NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein
Pkinase (PF00069, IPR000719): Protein kinase domain
182 TBL1Xprotein found in more fusions70.5334.097K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
LisH (PF08513, IPR013720, SM00667): LisH
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
LCE6A (PF15858, IPR031716): Late cornified envelope protein 6A family
183 TERF1interactor160.26762.118TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF)
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
184 TFAP4oncoprotein100.51112.149DivIC (PF04977, IPR007060): Septum formation initiator
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
DUF2407 (PF10302, IPR019413): DUF2407 ubiquitin-like domain
185 TLN2interactor100FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type)
Talin_middle (PF09141, IPR015224): Talin, middle domain
VBS (PF08913, IPR015009): Vinculin Binding Site
I_LWEQ (PF01608, IPR002558, SM00307): I/LWEQ domain
TAN (PF11640, IPR021668): Telomere-length maintenance and DNA damage repair
FERM_f0 (PF16511, IPR032425): N-terminal or F0 domain of Talin-head FERM
186 TP53suppressor510.199725.040DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
187 TRAF1oncoprotein90.25013.437HypA (PF01155, IPR000688): Hydrogenase/urease nickel incorporation, metallochaperone, hypA
SlyX (PF04102, IPR007236): SlyX
TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain
188 TRIM21interactor150.46218.720DUF313 (PF03754, IPR005508): Domain of unknown function (DUF313)
SPRY (PF00622, IPR003877, SM00449): SPRY domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
Prok-RING_1 (PF14446): Prokaryotic RING finger family 1
zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
189 TRRAPinteractor80.6432.337BALF1 (PF06861, IPR010677): BALF1 protein
BP28CT (PF08146, IPR012954, SM01036): BP28CT (NUC211) domain
DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
FAT (PF02259, IPR003151): FAT domain
FATC (PF02260, IPR003152): FATC domain
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361)
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
CLASP_N (PF12348, IPR024395): CLASP N terminal
Sec7_N (PF12783, IPR032691): Guanine nucleotide exchange factor in Golgi transport N-terminal
HEAT_EZ (PF13513): HEAT-like repeat
TRC8_N (PF13705, IPR025754): TRC8 N-terminal domain
ACDC (PF14733, IPR028078): AP2-coincident C-terminal
190 TTC21Ainteractor100MIT (PF04212, IPR007330, SM00745): MIT (microtubule interacting and transport) domain
23S_rRNA_IVP (PF05635, IPR012657): 23S rRNA-intervening sequence protein
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_21 (PF09976, IPR018704): Tetratricopeptide repeat-like domain
RPN7 (PF10602, IPR019585): 26S proteasome subunit RPN7
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_14 (PF13428): Tetratricopeptide repeat
TPR_17 (PF13431): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
YgaB (PF14182, IPR025572): YgaB-like protein
TPR_19 (PF14559): Tetratricopeptide repeat
Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat
SNAP (PF14938): Soluble NSF attachment protein, SNAP
191 TTC9Cinteractor50.7002.000TPR_17 (PF13431): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
192 TUBG1protein found in more fusions140.50017.270Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
193 TUBGCP3interactor70.5717.576Spc97_Spc98 (PF04130, IPR007259): Spc97 / Spc98 family
194 UBCprotein found in more fusions390.266334.548ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
195 UBE2Binteractor90.5004.808UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
196 UBE2D1interactor250.221123.175UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
197 UBXN7interactor130.56416.325UBX (PF00789, IPR001012, SM00166): UBX domain
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
Thioredoxin_7 (PF13899): Thioredoxin-like
UBA_4 (PF14555): UBA-like domain
198 UHRF2suppressor100.5284.998PHD (PF00628, IPR019787, SM00249): PHD-finger
SAD_SRA (PF02182, IPR003105, SM00466): SAD/SRA domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
TTD (PF12148, IPR021991): Tandem tudor domain within UHRF1
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
UBA2_C (PF16195, IPR032426): SUMO-activating enzyme subunit 2 C-terminus
199 USP37interactor120.50962.224UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
UCH_N (PF16674, IPR032069): N-terminal of ubiquitin carboxyl-terminal hydrolase 37
200 VCPprotein found in more fusions400.310285.524AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2
CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain
TniB (PF05621, IPR008868): Bacterial TniB protein
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
201 YAF2interactor60.7332.314DUF460 (PF04312, IPR007408): Protein of unknown function (DUF460)
OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain
Exo5 (PF09810, IPR019190): Exonuclease V - a 5' deoxyribonuclease
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
MPDZ_u10 (PF16667, IPR032078): Unstructured region 10 on multiple PDZ protein
YAF2_RYBP (PF17219): Yaf2/RYBP C-terminal binding motif
202 YWHAGprotein found in more fusions250.297131.86414-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
203 ZC3HC1interactor31.0000Rsm1 (PF08600, IPR013909): Rsm1-like
zf-C3HC (PF07967, IPR012935): C3HC zinc finger-like

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