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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)198
The number (and %) of the onco-proteins72 (36.36 %)
The number (and %) of the tumor suppressors25 (12.63 %)
Total number of binary PPIs (saturation %)1030 (5.28 %)
The number (and %) of affected PPIs196 (19.03 %)
The number of possible different fusions47
PPI diameter5
PPI radius3
The average degree of PPI9.677
Assortativity coefficient-0.2674
The network average Clustering coefficient0.448
The number (and %) of a zero Clustering coefficients22 (11.11 %)
The number (and %) of a zero Betweenness Centrality42 (21.21 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: MAML3,ISG15 All fusions
Proteins found in more fusions EEF1G (see 1 fusions); SMAD4 (see 2 fusions); TRIM25 (see 2 fusions); EEF1A1 (see 1 fusions); PPP1R10 (see 1 fusions); CSNK2A1/ELAVL1 (see 1 fusions); AHNAK (see 2 fusions); UBE2N (see 1 fusions); UBA1 (see 2 fusions); NFIX (see 3 fusions); EIF2AK2 (see 1 fusions); ACTB (see 3 fusions); PRDX1 (see 1 fusions); HSP90AA1/CALD1 (see 1 fusions); PSMA7 (see 2 fusions); PAFAH1B1 (see 1 fusions); PLOD3 (see 2 fusions); PRDX6 (see 1 fusions); HNRNPU/RPL24 (see 1 fusions); SENP1 (see 1 fusions); STAT1 (see 1 fusions); NEDD4 (see 1 fusions); UGP2 (see 1 fusions); PTBP1 (see 1 fusions); LMNA (see 3 fusions); G3BP1 (see 1 fusions); ELF3 (see 2 fusions); VCP (see 4 fusions); TKT (see 5 fusions); HSP90AA1 (see 2 fusions); ACTN1 (see 3 fusions); HSP90AB1 (see 1 fusions); SQSTM1 (see 5 fusions); SERBP1 (see 1 fusions); HNRNPL (see 2 fusions); SNRNP200 (see 3 fusions); UBE2L6 (see 2 fusions); BAG3 (see 4 fusions); EZR (see 2 fusions); RACK1 (see 3 fusions); HSPB1 (see 4 fusions); CSNK2A1 (see 1 fusions); DDX17 (see 3 fusions); ATP5A1 (see 1 fusions); GAPDH (see 2 fusions); HSPA8/HSPD1 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 MAML3parental protein90.083863.336Drf_GBD (PF06371, IPR010473, SM01140): Diaphanous GTPase-binding Domain
Rtf2 (PF04641, IPR027799): Rtf2 RING-finger
MamL-1 (PF09596, IPR019082): MamL-1 domain
DUF2459 (PF09601, IPR011727): Protein of unknown function (DUF2459)
Kin17_mid (PF10357, IPR019447): Domain of Kin17 curved DNA-binding protein
WBP-1 (PF11669, IPR021684): WW domain-binding protein 1
SprA-related (PF12118, IPR021973): SprA-related family
DUF3682 (PF12446, IPR022152): Protein of unknown function (DUF3682)
CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
AAA_23 (PF13476): AAA domain
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
FAM70 (PF14967, IPR028014): FAM70 protein
2 ISG15parental protein1870.04228752.920ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
3 AAASinteractor100PD40 (PF07676, IPR011659): WD40-like Beta Propeller Repeat
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
DUF4613 (PF15390, IPR028041): Domain of unknown function (DUF4613)
4 AARSinteractor70.4767.972DHHA1 (PF02272, IPR003156): DHHA1 domain
Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal
tRNA-synt_2c (PF01411, IPR018164): tRNA synthetases class II (A)
tRNA_SAD (PF07973, IPR012947, SM00863): Threonyl and Alanyl tRNA synthetase second additional domain
5 ABCF2interactor40.5003.139ABC_tran (PF00005, IPR003439): ABC transporter
VIT1 (PF01988, IPR008217): VIT family
Rop (PF01815, IPR000769): Rop protein
ABC_tran_Xtn (PF12848, IPR032781): ABC transporter
AAA_21 (PF13304, IPR003959): AAA domain, putative AbiEii toxin, Type IV TA system
6 ACLYinteractor50.6001.624ATP-grasp_2 (PF08442, IPR013650): ATP-grasp domain
Citrate_synt (PF00285, IPR002020): Citrate synthase, C-terminal domain
CoA_binding (PF02629, IPR003781, SM00881): CoA binding domain
Ligase_CoA (PF00549, IPR005811): CoA-ligase
Citrate_bind (PF16114, IPR032263): ATP citrate lyase citrate-binding
7 ACOT8interactor1004HBT_3 (PF13622): Thioesterase-like superfamily
8 ACTA1interactor90.33317.900Actin (PF00022, IPR004000, SM00268): Actin
9 ACTBoncoprotein180.301127.503Actin (PF00022, IPR004000, SM00268): Actin
10 ACTN1protein found in more fusions130.48520.930CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
Dak2 (PF02734, IPR004007, SM01120): DAK2 domain
EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand
Spectrin (PF00435, IPR002017): Spectrin repeat
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
Uds1 (PF15456, IPR029191): Up-regulated During Septation
11 ACTN4interactor120.39421.139CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand
Spectrin (PF00435, IPR002017): Spectrin repeat
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
Uds1 (PF15456, IPR029191): Up-regulated During Septation
12 AHNAKsuppressor100.44412.115DUF945 (PF06097, IPR010352): Bacterial protein of unknown function (DUF945)
ELFV_dehydrog_N (PF02812, IPR006097): Glu/Leu/Phe/Val dehydrogenase, dimerisation domain
T2SSN (PF01203, IPR022792): Type II secretion system (T2SS), protein N
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
TT_ORF2a (PF08197, IPR013267): pORF2a truncated protein
DUF2993 (PF11209, IPR021373): Protein of unknown function (DUF2993)
DUF4097 (PF13349, IPR025164): Putative adhesin
Ntox37 (PF15535, IPR029108): Bacterial toxin 37
13 AIFM1oncoprotein50.6002.503Pyr_redox_2 (PF07992, IPR023753): Pyridine nucleotide-disulphide oxidoreductase
AIF_C (PF14721, IPR029324): Apoptosis-inducing factor, mitochondrion-associated, C-term
AIF-MLS (PF14962, IPR032773): Mitochondria Localisation Sequence
14 ALDOAinteractor140.55116.796Glycolytic (PF00274, IPR000741): Fructose-bisphosphate aldolase class-I
15 ANXA2interactor80.42910.843Annexin (PF00191, IPR018502, SM00335): Annexin
16 ANXA3interactor100Annexin (PF00191, IPR018502, SM00335): Annexin
RPT (PF13446, IPR025305): A repeated domain in UCH-protein
17 ANXA5oncoprotein40.6670.440Annexin (PF00191, IPR018502, SM00335): Annexin
18 ARID5Boncoprotein31.0000ARID (PF01388, IPR001606, SM00501): ARID/BRIGHT DNA binding domain
19 ATIConcoprotein70.3819.268AICARFT_IMPCHas (PF01808, IPR002695, SM00798): AICARFT/IMPCHase bienzyme
MGS (PF02142, IPR011607, SM00851): MGS-like domain
20 ATP5A1protein found in more fusions130.54512.632ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain
ATP-synt_ab_C (PF00306, IPR000793): ATP synthase alpha/beta chain, C terminal domain
ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain
21 ATP5Binteractor90.5569.950AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain
ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain
NACHT (PF05729): NACHT domain
22 ATXN2interactor40.6671.682LsmAD (PF06741, IPR009604): LsmAD domain
PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446)
Spt20 (PF12090, IPR021950): Spt20 family
SM-ATX (PF14438, IPR025852): Ataxin 2 SM domain
23 ATXN2Linteractor30.6670.400LsmAD (PF06741, IPR009604): LsmAD domain
PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
SM-ATX (PF14438, IPR025852): Ataxin 2 SM domain
24 BAG3oncoprotein330.153353.349BAG (PF02179, IPR003103, SM00264): BAG domain
WW (PF00397, IPR001202, SM00456): WW domain
25 CALD1protein found in more fusions50.9000.400Caldesmon (PF02029, IPR006018): Caldesmon
DUF1049 (PF06305, IPR010445): Protein of unknown function (DUF1049)
26 CAND1interactor490.151971.866Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981)
HEAT (PF02985, IPR000357): HEAT repeat
TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20)
RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
27 CBX4oncoprotein60.300365.226Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region
CBX7_C (PF17218): CBX family C-terminal motif
28 CCNL1interactor100Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
DUF936 (PF06075, IPR010341): Plant protein of unknown function (DUF936)
29 CCT2interactor130.42325.990Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
30 CCT3interactor120.288113.850Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
31 CCT4interactor70.6194.810Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
32 CFL1interactor160.39248.523Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
33 CHD1suppressor30.6670.182CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain
Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
Serglycin (PF04360, IPR007455): Serglycin
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Zip (PF02535, IPR003689): ZIP Zinc transporter
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
DUF4208 (PF13907, IPR025260): Domain of unknown function (DUF4208)
PNISR (PF15996, IPR031937): Arginine/serine-rich protein PNISR
34 CHMP5interactor200Snf7 (PF03357, IPR005024): Snf7
35 CLIC1interactor21.0000GST_N_2 (PF13409, IPR004045): Glutathione S-transferase, N-terminal domain
GST_C_2 (PF13410): Glutathione S-transferase, C-terminal domain
36 CLK1interactor60.5003.619PDGF_N (PF04692, IPR006782): Platelet-derived growth factor, N terminal region
Pkinase (PF00069, IPR000719): Protein kinase domain
37 CLTConcoprotein100.37819.535Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker
Clathrin_propel (PF01394, IPR022365): Clathrin propeller repeat
Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS
Clathrin_H_link (PF13838): Clathrin-H-link
38 CSNK2A1oncoprotein270.182289.682Pkinase (PF00069, IPR000719): Protein kinase domain
39 CTNNB1oncoprotein180.229166.321Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361)
HEAT_EZ (PF13513): HEAT-like repeat
40 DDB2suppressor90.39311.120WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
41 DDX17protein found in more fusions180.316140.541CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Ferritin (PF00210, IPR008331): Ferritin-like domain
GRP (PF07172, IPR010800): Glycine rich protein family
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
42 DDX42interactor60.4007.219DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
43 DDX58suppressor60.5005.000DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
RIG-I_C-RD (PF11648, IPR021673): C-terminal domain of RIG-I
AAA_22 (PF13401, IPR003593): AAA domain
Syntaxin_2 (PF14523): Syntaxin-like protein
CARD_2 (PF16739, IPR031964): Caspase recruitment domain
44 DEPDC7interactor100DEP (PF00610, IPR000591, SM00049): Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)
45 DNAJB1suppressor50.9000.244DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
46 DNAJB4suppressor60.8670.644DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
47 DSTNinteractor80.4647.461Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
48 DYRK1Aoncoprotein50.5002.295DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755)
Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region
Pkinase (PF00069, IPR000719): Protein kinase domain
FAM199X (PF15814, IPR029672): Protein family FAM199X
49 EEF1A1suppressor260.230165.122GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
50 EEF1A2oncoprotein90.36169.140GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
51 EEF1Gprotein found in more fusions90.35716.232EF1G (PF00647, IPR001662): Elongation factor 1 gamma, conserved domain
GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain
GST_N (PF02798, IPR004045): Glutathione S-transferase, N-terminal domain
SAPS (PF04499, IPR007587): SIT4 phosphatase-associated protein
52 EEF2interactor190.27589.859EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus
EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV
GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
EFG_II (PF14492, IPR009022): Elongation Factor G, domain II
53 EIF2AK2oncoprotein60.7001.190dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
Pkinase (PF00069, IPR000719): Protein kinase domain
54 EIF4G1oncoprotein50.6002.186DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
MA3 (PF02847, IPR003891, SM00544): MA3 domain
MIF4G (PF02854, IPR003890, SM00543): MIF4G domain
Neisseria_TspB (PF05616, IPR008708): Neisseria meningitidis TspB protein
W2 (PF02020, IPR003307, SM00515): eIF4-gamma/eIF5/eIF2-epsilon
55 ELAVL1oncoprotein410.112844.481RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
56 ELF3oncoprotein70.5335.463AT_hook (PF02178, IPR017956, SM00384): AT hook motif
Ets (PF00178, IPR000418, SM00413): Ets-domain
SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain
57 ENO1oncoprotein210.271203.317Enolase_C (PF00113, IPR020810): Enolase, C-terminal TIM barrel domain
Enolase_N (PF03952, IPR020811): Enolase, N-terminal domain
58 EPPK1interactor21.0000DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840)
HupF_HypC (PF01455, IPR001109): HupF/HypC family
Plectin (PF00681, IPR001101, SM00250): Plectin repeat
RPA_interact_N (PF14766, IPR028158): Replication protein A interacting N-terminal
59 EPRSinteractor60.4007.977GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain
HGTP_anticodon (PF03129, IPR004154): Anticodon binding domain
ProRS-C_1 (PF09180, IPR016061, SM00946): Prolyl-tRNA synthetase, C-terminal
tRNA-synt_1c (PF00749, IPR020058): tRNA synthetases class I (E and Q), catalytic domain
tRNA-synt_1c_C (PF03950, IPR020059): tRNA synthetases class I (E and Q), anti-codon binding domain
tRNA-synt_2b (PF00587, IPR002314): tRNA synthetase class II core domain (G, H, P, S and T)
WHEP-TRS (PF00458, IPR000738, SM00991): WHEP-TRS domain
60 ERCC2oncoprotein30.6670.400DEAD_2 (PF06733, IPR010614): DEAD_2
HBB (PF06777, IPR010643): Helical and beta-bridge domain
ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit
Helicase_C_2 (PF13307, IPR006555): Helicase C-terminal domain
TIR_2 (PF13676, IPR000157): TIR domain
SesA (PF17107, IPR031352): N-terminal domain on NACHT_NTPase and P-loop NTPases
61 EZRprotein found in more fusions190.26176.510DUF106 (PF01956, IPR002809): Integral membrane protein DUF106
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
62 FAM120Cinteractor21.0000PRIMA1 (PF16101): Proline-rich membrane anchor 1
63 FARS2interactor21.0000FDX-ACB (PF03147, IPR005121, SM00896): Ferredoxin-fold anticodon binding domain
tRNA-synt_2 (PF00152, IPR004364): tRNA synthetases class II (D, K and N)
tRNA-synt_2d (PF01409, IPR002319): tRNA synthetases class II core domain (F)
64 FASNinteractor50.6670.800Acyl_transf_1 (PF00698, IPR014043): Acyl transferase domain
ADH_zinc_N (PF00107, IPR013149): Zinc-binding dehydrogenase
ketoacyl-synt (PF00109, IPR014030): Beta-ketoacyl synthase, N-terminal domain
Ketoacyl-synt_C (PF02801, IPR014031): Beta-ketoacyl synthase, C-terminal domain
KR (PF08659, IPR013968, SM00130): KR domain
L27 (PF02828, IPR014775, SM00569): L27 domain
Methyltransf_12 (PF08242, IPR013217): Methyltransferase domain
PP-binding (PF00550, IPR009081): Phosphopantetheine attachment site
Thioesterase (PF00975, IPR001031): Thioesterase domain
YjeF_N (PF03853, IPR004443): YjeF-related protein N-terminus
ADH_zinc_N_2 (PF13602): Zinc-binding dehydrogenase
PS-DH (PF14765, IPR020807): Polyketide synthase dehydratase
KAsynt_C_assoc (PF16197, IPR032821): Ketoacyl-synthetase C-terminal extension
65 FLNAsuppressor180.288133.052CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
Filamin (PF00630, IPR017868): Filamin/ABP280 repeat
66 FLNBoncoprotein100.40019.098CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
Filamin (PF00630, IPR017868): Filamin/ABP280 repeat
PapC_N (PF13954, IPR025885): PapC N-terminal domain
67 FUBP3interactor21.0000DUF1897 (PF09005, IPR015096): Domain of unknown function (DUF1897)
KH_1 (PF00013, IPR004088, SM00322): KH domain
68 FUT4interactor100Glyco_transf_10 (PF00852, IPR001503): Glycosyltransferase family 10 (fucosyltransferase) C-term
Glyco_tran_10_N (PF17039, IPR031481): Fucosyltransferase, N-terminal
69 G3BP1protein found in more fusions120.34525.514NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306)
PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
70 GANABsuppressor60.66728.249Glyco_hydro_31 (PF01055, IPR000322): Glycosyl hydrolases family 31
Gal_mutarotas_2 (PF13802, IPR025887): Galactose mutarotase-like
DUF5110 (PF17137): Domain of unknown function (DUF5110)
71 GAPDHoncoprotein160.49530.450Gp_dh_C (PF02800, IPR020829): Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
Gp_dh_N (PF00044, IPR020828, SM00846): Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
OstA (PF03968, IPR005653): OstA-like protein
72 GBP1suppressor30.6670.333GBP (PF02263, IPR015894): Guanylate-binding protein, N-terminal domain
GBP_C (PF02841, IPR003191): Guanylate-binding protein, C-terminal domain
73 GDI2interactor50.7000.759GDI (PF00996, IPR018203): GDP dissociation inhibitor
74 GPIinteractor60.6672.024PGI (PF00342, IPR001672): Phosphoglucose isomerase
75 GSRinteractor70.4005.231Pyr_redox_2 (PF07992, IPR023753): Pyridine nucleotide-disulphide oxidoreductase
Pyr_redox_dim (PF02852, IPR004099): Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
76 GSTP1suppressor200GST_N (PF02798, IPR004045): Glutathione S-transferase, N-terminal domain
GST_C_3 (PF14497, IPR004046): Glutathione S-transferase, C-terminal domain
77 HDAC6oncoprotein220.271114.408Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
PSGP (PF07276, IPR009900): Apopolysialoglycoprotein (PSGP)
zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
78 HELZ2interactor100RNB (PF00773, SM00955): RNB domain
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
AAA_11 (PF13086): AAA domain
AAA_12 (PF13087): AAA domain
79 HERC5interactor110.24434.062Peptidase_S51 (PF03575, IPR005320): Peptidase family S51
RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
80 HNRNPA2B1oncoprotein220.225226.014RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
81 HNRNPKoncoprotein240.237221.815ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain
KH_1 (PF00013, IPR004088, SM00322): KH domain
82 HNRNPLprotein found in more fusions160.43838.895RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Dscam_C (PF12355, IPR021012): Down syndrome cell adhesion molecule C terminal
RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
83 HNRNPUprotein found in more fusions270.202312.695CDC45 (PF02724, IPR003874): CDC45-like protein
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SAP (PF02037, IPR003034, SM00513): SAP domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
AAA_33 (PF13671): AAA domain
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
84 HSP90AA1oncoprotein390.205504.070HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
85 HSP90AB1oncoprotein340.261222.694HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
86 HSPA1Ainteractor170.368133.884HSP70 (PF00012, IPR013126): Hsp70 protein
87 HSPA4interactor210.33385.156Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region
HSP70 (PF00012, IPR013126): Hsp70 protein
TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5
88 HSPA8oncoprotein210.362167.891HSP70 (PF00012, IPR013126): Hsp70 protein
89 HSPB1oncoprotein330.185639.967HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
90 HSPD1suppressor160.35847.724Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
91 IFIT1interactor90.41719.491TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
ANAPC5 (PF12862, IPR026000): Anaphase-promoting complex subunit 5
Sec16_C (PF12931, IPR024298): Sec23-binding domain of Sec16
TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_17 (PF13431): Tetratricopeptide repeat
DUF4268 (PF14088, IPR025364): Domain of unknown function (DUF4268)
TPR_19 (PF14559): Tetratricopeptide repeat
92 IFIT2interactor50.8001.487TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
HTH_WhiA (PF02650, IPR023054): WhiA C-terminal HTH domain
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_17 (PF13431): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
Mad3_BUB1_I_2 (PF17014, IPR031522): Putative Mad3/BUB1 like region 1 protein
93 IFIT3interactor130.34842.116TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_17 (PF13431): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
94 IFIT5interactor40.6672.142TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
Sec16_C (PF12931, IPR024298): Sec23-binding domain of Sec16
TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_15 (PF13429): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
95 IFNA14interactor41.0000Interferon (PF00143, IPR000471, SM00076): Interferon alpha/beta domain
96 IFNA2interactor31.0000Interferon (PF00143, IPR000471, SM00076): Interferon alpha/beta domain
97 IFNA5interactor50.8001.333Interferon (PF00143, IPR000471, SM00076): Interferon alpha/beta domain
98 IFNA8interactor31.0000Interferon (PF00143, IPR000471, SM00076): Interferon alpha/beta domain
99 IQGAP1interactor220.277113.352CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
DUF87 (PF01935, IPR002789): Domain of unknown function DUF87
IDEAL (PF08858, IPR014957, SM00914): IDEAL domain
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase
RasGAP_C (PF03836, IPR000593): RasGAP C-terminus
WW (PF00397, IPR001202, SM00456): WW domain
100 LAP3interactor31.0000Peptidase_M17 (PF00883, IPR000819): Cytosol aminopeptidase family, catalytic domain
Peptidase_M17_N (PF02789, IPR008283): Cytosol aminopeptidase family, N-terminal domain
PAW (PF04721, IPR006588, SM00613): PNGase C-terminal domain, mannose-binding module PAW
101 LDHAinteractor180.33859.955Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain
Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain
102 LGMNinteractor100Peptidase_C13 (PF01650, IPR001096): Peptidase C13 family
103 LMAN2interactor2022.103Lectin_leg-like (PF03388, IPR005052): Legume-like lectin family
Tad (PF13400, IPR028087): Putative Flp pilus-assembly TadE/G-like
104 LMNAprotein found in more fusions150.220105.245Filament (PF00038, IPR001664): Intermediate filament protein
LTD (PF00932, IPR001322): Lamin Tail Domain
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
105 MAML1interactor31.0000MamL-1 (PF09596, IPR019082): MamL-1 domain
Kri1 (PF05178, IPR018034): KRI1-like family
PRIMA1 (PF16101): Proline-rich membrane anchor 1
106 MAP4oncoprotein50.4005.000SdiA-regulated (PF06977, IPR009722): SdiA-regulated
Tubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeat
DUF3275 (PF11679, IPR021693): Protein of unknown function (DUF3275)
107 MDH1interactor50.7001.500Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain
Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain
108 MEPCEinteractor130.35933.050Bin3 (PF06859, IPR010675): Bicoid-interacting protein 3 (Bin3)
Methyltransf_23 (PF13489): Methyltransferase domain
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
DLEU7 (PF15760, IPR031510): Leukemia-associated protein 7
109 MSNoncoprotein170.30860.658DUF883 (PF05957, IPR010279): Bacterial protein of unknown function (DUF883)
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
110 MX1interactor31.0000Dynamin_M (PF01031, IPR000375): Dynamin central region
GED (PF02212, IPR003130, SM00302): Dynamin GTPase effector domain
Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family
111 MYH9suppressor260.246166.505IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
112 MYOFinteractor100C2 (PF00168, IPR000008, SM00239): C2 domain
FerA (PF08165, IPR012560): FerA (NUC095) domain
FerB (PF08150, IPR012561): FerB (NUC096) domain
FerI (PF08151, IPR012968): FerI (NUC094) domain
Pex24p (PF06398, IPR010482): Integral peroxisomal membrane peroxin
Ferlin_C (PF16165, IPR032362): Ferlin C-terminus
113 NACAoncoprotein30.6670.618NAC (PF01849, IPR002715): NAC domain
RNA_pol_Rpo13 (PF12136, IPR021985): RNA polymerase Rpo13 subunit HTH domain
CitT (PF12431, IPR028141): Transcriptional regulator
114 NEDD4suppressor90.35715.731Rota_NS26 (PF01525, IPR002512): Rotavirus NS26
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
115 NFIXoncoprotein40.33361.654CTF_NFI (PF00859, IPR000647): CTF/NF-I family transcription modulation region
NfI_DNAbd_pre-N (PF10524, IPR019548): Nuclear factor I protein pre-N-terminus
MH1 (PF03165, IPR003619, SM00523): MH1 domain
116 NFX1interactor70.048186.971R3H (PF01424, IPR001374, SM00393): R3H domain
XPG_I (PF00867, IPR006086, SM00484): XPG I-region
zf-NF-X1 (PF01422, IPR000967, SM00438): NF-X1 type zinc finger
117 NOTCH1suppressor120.164523.141Ank (PF00023, IPR002110, SM00248): Ankyrin repeat
EGF (PF00008, IPR000742, SM00181): EGF-like domain
EGF_2 (PF07974, IPR013111): EGF-like domain
EGF_alliinase (PF04863, IPR006947): Alliinase EGF-like domain
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
NOD (PF06816, IPR010660): NOTCH protein
NODP (PF07684, IPR011656): NOTCH protein
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
Notch (PF00066, IPR000800, SM00004): LNR domain
DUF3454 (PF11936, IPR024600): Domain of unknown function (DUF3454)
hEGF (PF12661, IPR013032): Human growth factor-like EGF
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
118 NUP43interactor21.0000WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
119 OGDHinteractor30.6670.500E1_dh (PF00676, IPR001017): Dehydrogenase E1 component
Transket_pyr (PF02779, IPR005475, SM00861): Transketolase, pyrimidine binding domain
2-oxogl_dehyd_N (PF16078, IPR032106): 2-oxoglutarate dehydrogenase N-terminus
OxoGdeHyase_C (PF16870, IPR031717): 2-oxoglutarate dehydrogenase C-terminal
120 PAFAH1B1suppressor60.6002.133LisH (PF08513, IPR013720, SM00667): LisH
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
121 PALLDinteractor70.5244.858I-set (PF07679, IPR013098): Immunoglobulin I-set domain
122 PFN1suppressor50.8001.441Profilin (PF00235, IPR005455, SM00392): Profilin
123 PGDoncoprotein60.4673.1836PGD (PF00393, IPR006114): 6-phosphogluconate dehydrogenase, C-terminal domain
NAD_binding_2 (PF03446, IPR006115): NAD binding domain of 6-phosphogluconate dehydrogenase
124 PGK1interactor170.41236.076PGK (PF00162, IPR001576): Phosphoglycerate kinase
125 PHGDHinteractor70.4298.0352-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
126 PKMoncoprotein170.41944.929PK (PF00224, IPR015793): Pyruvate kinase, barrel domain
PK_C (PF02887, IPR015795): Pyruvate kinase, alpha/beta domain
127 PLEConcoprotein100.35616.782CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding
CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
FUSC (PF04632, IPR006726): Fusaric acid resistance protein family
RNA_pol_Rbc25 (PF08292, IPR013238): RNA polymerase III subunit Rpc25
S10_plectin (PF03501, IPR005326): Plectin/S10 domain
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
DUF2229 (PF09989, IPR018709): CoA enzyme activase uncharacterised domain (DUF2229)
Plectin (PF00681, IPR001101, SM00250): Plectin repeat
YlqD (PF11068, IPR021297): YlqD protein
Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein
DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391)
DUF4140 (PF13600, IPR025554): N-terminal domain of unknown function (DUF4140)
128 PLOD1interactor31.00002OG-FeII_Oxy (PF03171, IPR005123): 2OG-Fe(II) oxygenase superfamily
Anp1 (PF03452, IPR005109): Anp1
129 PLOD3protein found in more fusions50.8330.6672OG-FeII_Oxy (PF03171, IPR005123): 2OG-Fe(II) oxygenase superfamily
Anp1 (PF03452, IPR005109): Anp1
130 PLS1interactor50.6002.583CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain
EF-hand_5 (PF13202, IPR002048): EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
131 PLS3interactor60.5334.633CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
EF-hand_5 (PF13202, IPR002048): EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
132 PPM1Binteractor31.0000PP2C (PF00481, IPR001932): Protein phosphatase 2C
PP2C_C (PF07830, IPR012911, SM00332): Protein serine/threonine phosphatase 2C, C-terminal domain
133 PPP1R10protein found in more fusions50.6672.143Med26 (PF08711, IPR017923): TFIIS helical bundle-like domain
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
134 PRDX1oncoprotein80.5247.235AhpC-TSA (PF00578, IPR000866): AhpC/TSA family
1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin
135 PRDX6protein found in more fusions90.32114.483AhpC-TSA (PF00578, IPR000866): AhpC/TSA family
1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin
136 PSMA7protein found in more fusions40.6670.154Proteasome (PF00227, IPR001353): Proteasome subunit
Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
137 PTBP1oncoprotein170.375121.182RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
138 PYM1interactor21.0000CcmD (PF04995, IPR007078): Heme exporter protein D (CcmD)
Mago-bind (PF09282, IPR015362): Mago binding
AAA_23 (PF13476): AAA domain
139 QTRT2interactor100TGT (PF01702, IPR002616): Queuine tRNA-ribosyltransferase
140 RACK1suppressor90.46410.699WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
141 RAI1interactor100Lin-8 (PF03353, IPR005020): Ras-mediated vulval-induction antagonist
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
zf-HC5HC2H (PF13771): PHD-like zinc-binding domain
142 RANoncoprotein40.5002.208Ras (PF00071, IPR001806, SM00173): Ras family
143 RBBP4oncoprotein80.46451.858eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein
CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
144 RBM15Binteractor100CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RRM_3 (PF08777, IPR014886): RNA binding motif
SPOC (PF07744, IPR012921): SPOC domain
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
DUF5094 (PF17015, IPR031519): Domain of unknown function (DUF5094)
145 RBPJinteractor70.143312.554BTD (PF09270, IPR015350): Beta-trefoil DNA-binding domain
LAG1-DNAbind (PF09271, IPR015351): LAG1, DNA binding
TIG (PF01833, IPR002909): IPT/TIG domain
146 RDH11interactor200adh_short (PF00106, IPR002198): short chain dehydrogenase
AdoHcyase_NAD (PF00670, IPR015878, SM00997): S-adenosyl-L-homocysteine hydrolase, NAD binding domain
Acetyltransf_13 (PF13880, IPR028009): ESCO1/2 acetyl-transferase
147 RGS3oncoprotein100C2 (PF00168, IPR000008, SM00239): C2 domain
CDC45 (PF02724, IPR003874): CDC45-like protein
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
Astro_capsid_p (PF12226, IPR022027): Turkey astrovirus capsid protein
148 RPL24protein found in more fusions100.35662.722MAS20 (PF02064, IPR002056): MAS20 protein import receptor
Ribosomal_L24e (PF01246, IPR000988): Ribosomal protein L24e
149 RPL27Ainteractor80.57147.319Ribosomal_L27A (PF00828, IPR021131): Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
150 RPS27Ainteractor60.3337.260DUF1049 (PF06305, IPR010445): Protein of unknown function (DUF1049)
151 SCMH1interactor3021.758MBT (PF02820, IPR004092, SM00561): mbt repeat
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
SLED (PF12140, IPR021987): SLED domain
RBR (PF17208): RNA binding Region
152 SENP1protein found in more fusions60.4005.446Peptidase_C48 (PF02902, IPR003653): Ulp1 protease family, C-terminal catalytic domain
153 SEPT2oncoprotein60.4674.033FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger
Septin (PF00735, IPR000038): Septin
154 SERBP1protein found in more fusions110.42219.025HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family
FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
155 SERPINB5suppressor60.4006.619Serpin (PF00079, IPR023796, SM00093): Serpin (serine protease inhibitor)
156 SF3A2interactor120.34827.717Cytadhesin_P30 (PF07271, IPR009896): Cytadhesin P30/P32
PRP4 (PF08799, IPR014906): pre-mRNA processing factor 4 (PRP4) like
Totivirus_coat (PF05518, IPR008871): Totivirus coat protein
zf-met (PF12874): Zinc-finger of C2H2 type
ARL6IP6 (PF15062, IPR029383): Haemopoietic lineage transmembrane helix
SF3A2 (PF16835, IPR031781): Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11)
157 SF3B4interactor60.5333.975RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
158 SFNsuppressor160.24857.78314-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
159 SIN3Aoncoprotein70.286120.664Sin3_corepress (PF08295, IPR013194, SM00761): Sin3 family co-repressor
PAH (PF02671, IPR003822, SM00309): Paired amphipathic helix repeat
Sin3a_C (PF16879, IPR031693): C-terminal domain of Sin3a protein
160 SMAD4suppressor70.4678.048MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
161 SNRNP200protein found in more fusions80.6192.971DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
DUF603 (PF04645, IPR006739): Protein of unknown function, DUF603
Sec63 (PF02889, IPR004179, SM00973): Sec63 Brl domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
162 SQSTM1oncoprotein110.46711.569PB1 (PF00564, IPR000270, SM00666): PB1 domain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
UBA_5 (PF16577, IPR015940): UBA domain
163 STAT1suppressor100.41713.459SH2 (PF00017, IPR000980, SM00252): SH2 domain
STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain
STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain
STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
STAT1_TAZ2bind (PF12162, IPR022752): STAT1 TAZ2 binding domain
164 STK38interactor70.20095.450MEKHLA (PF08670, IPR013978): MEKHLA domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
165 SUPT5Hinteractor100.178362.820KOW (PF00467, IPR005824, SM00739): KOW motif
Ribonuc_P_40 (PF08584, IPR013893): Ribonuclease P 40kDa (Rpp40) subunit
Spt5-NGN (PF03439, IPR005100): Early transcription elongation factor of RNA pol II, NGN section
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
DUF3912 (PF13051, IPR025023): Protein of unknown function (DUF3912)
166 TAF2interactor21.0000DUF496 (PF04363, IPR007458): Protein of unknown function (DUF496)
HEAT (PF02985, IPR000357): HEAT repeat
Peptidase_M1 (PF01433, IPR014782): Peptidase family M1
HEAT_2 (PF13646): HEAT repeats
AP3D1 (PF06375): AP-3 complex subunit delta-1
167 TAGLNsuppressor90.38914.225Calponin (PF00402, IPR000557): Calponin family repeat
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
168 TARSinteractor70.38113.470HGTP_anticodon (PF03129, IPR004154): Anticodon binding domain
TGS (PF02824, IPR004095): TGS domain
tRNA-synt_2b (PF00587, IPR002314): tRNA synthetase class II core domain (G, H, P, S and T)
tRNA_SAD (PF07973, IPR012947, SM00863): Threonyl and Alanyl tRNA synthetase second additional domain
169 TKTprotein found in more fusions210.31694.690Transket_pyr (PF02779, IPR005475, SM00861): Transketolase, pyrimidine binding domain
Transketolase_C (PF02780, IPR005476): Transketolase, C-terminal domain
Transketolase_N (PF00456, IPR005474): Transketolase, thiamine diphosphate binding domain
170 TMOD3interactor70.5714.639Tropomodulin (PF03250, IPR004934): Tropomodulin
Usher (PF00577, IPR000015): Outer membrane usher protein
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
171 TOP2Aoncoprotein60.4673.781DNA_gyraseB (PF00204, IPR013506): DNA gyrase B
DTHCT (PF08070, IPR012542): DTHCT (NUC029) region
HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
Sec62 (PF03839, IPR004728): Translocation protein Sec62
Toprim (PF01751, IPR006171, SM00493): Toprim domain
DNA_topoisoIV (PF00521, IPR002205, SM00434): DNA gyrase/topoisomerase IV, subunit A
PHC2_SAM_assoc (PF16616): Unstructured region on Polyhomeotic-like protein 1 and 2
TOPRIM_C (PF16898, IPR031660): C-terminal associated domain of TOPRIM
172 TRIM25protein found in more fusions180.176103.380Fes1 (PF08609, IPR013918): Nucleotide exchange factor Fes1
Pox_Rif (PF03340, IPR005008): Poxvirus rifampicin resistance protein
SPRY (PF00622, IPR003877, SM00449): SPRY domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
173 TXNRD1interactor50.4004.558Glutaredoxin (PF00462, IPR002109): Glutaredoxin
Pyr_redox_2 (PF07992, IPR023753): Pyridine nucleotide-disulphide oxidoreductase
Pyr_redox_dim (PF02852, IPR004099): Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
174 UBA1protein found in more fusions130.34832.197ThiF (PF00899, IPR000594): ThiF family
E1_UFD (PF09358, IPR018965, SM00985): Ubiquitin fold domain
UBA_e1_thiolCys (PF10585, IPR019572): Ubiquitin-activating enzyme active site
175 UBA7oncoprotein21.0000ThiF (PF00899, IPR000594): ThiF family
E1_UFD (PF09358, IPR018965, SM00985): Ubiquitin fold domain
176 UBAP2Linteractor40.5001.439CUE (PF02845, IPR003892, SM00546): CUE domain
DUF3484 (PF11983, IPR021873): Membrane-attachment and polymerisation-promoting switch
DUF3697 (PF12478, IPR022166): Ubiquitin-associated protein 2
UBA_4 (PF14555): UBA-like domain
Comm (PF15957, IPR031878): Commissureless
177 UBE2D3interactor90.39313.864UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
178 UBE2L6protein found in more fusions60.5004.400UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
179 UBE2Nprotein found in more fusions100.36174.290UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
180 UGP2protein found in more fusions31.0000UDPGP (PF01704, IPR002618): UTP--glucose-1-phosphate uridylyltransferase
181 USP18interactor100TAFII55_N (PF04658, IPR006751): TAFII55 protein conserved region
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
182 USP21interactor40.6671.000UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
183 UTP4interactor21.0000CPSF_A (PF03178, IPR004871): CPSF A subunit region
PD40 (PF07676, IPR011659): WD40-like Beta Propeller Repeat
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Frtz (PF11768, IPR024511): WD repeat-containing and planar cell polarity effector protein Fritz
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
PQQ_2 (PF13360, IPR002372): PQQ-like domain
184 VCPprotein found in more fusions350.168370.068AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2
CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain
TniB (PF05621, IPR008868): Bacterial TniB protein
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
185 VIMsuppressor80.4767.831Filament (PF00038, IPR001664): Intermediate filament protein
Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region
186 WARSinteractor40.5002.538tRNA-synt_1b (PF00579, IPR002305): tRNA synthetases class I (W and Y)
WHEP-TRS (PF00458, IPR000738, SM00991): WHEP-TRS domain
187 WDR1interactor140.42929.667eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
PQQ (PF01011, IPR002372, SM00564): PQQ enzyme repeat
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
188 WDR33interactor30.6670.889Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
189 XRCC5suppressor120.40023.278Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain
Ku_PK_bind (PF08785, IPR014893): Ku C terminal domain like
190 XRCC6oncoprotein200.251200.365Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain
SAP (PF02037, IPR003034, SM00513): SAP domain
191 YTHDC1interactor30.6670.667DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM)
Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family
YTH (PF04146, IPR007275): YT521-B-like domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
TFB6 (PF17110, IPR031349): Subunit 11 of the general transcription factor TFIIH
192 YTHDF3interactor100Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
YTH (PF04146, IPR007275): YT521-B-like domain
193 ZBTB1interactor80.107215.297BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
zf-BED (PF02892, IPR003656, SM00614): BED zinc finger
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
194 ZC3H15interactor30.6670.810zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
Torus (PF16131, IPR032297): Torus domain
DFRP_C (PF16543, IPR032378): DRG Family Regulatory Proteins, Tma46
195 ZC3HAV1interactor31.0000PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain
WWE (PF02825, IPR004170, SM00678): WWE domain
196 ZNF281oncoprotein21.0000CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
GRP (PF07172, IPR010800): Glycine rich protein family
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
RhlB (PF12300, IPR022077): ATP-dependent RNA helicase RhlB
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
zf-C2H2_4 (PF13894): C2H2-type zinc finger
197 ZNF318oncoprotein100MAS20 (PF02064, IPR002056): MAS20 protein import receptor
zf-U1 (PF06220, IPR013085, SM00451): U1 zinc finger
Phage_Gp23 (PF10669, IPR018926): Protein gp23 (Bacteriophage A118)
DUF2951 (PF11166, IPR021337): Protein of unknown function (DUF2951)
FAM177 (PF14774, IPR028260): FAM177 family
TMEM171 (PF15471, IPR029173): Transmembrane protein family 171
PRIMA1 (PF16101): Proline-rich membrane anchor 1
198 ZZZ3interactor100Cript (PF10235, IPR019367): Microtubule-associated protein CRIPT
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type

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