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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins PPP2CA, RANGAP1 (from a repository: Sat Aug 10 23:25:01 2019)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)311
The number (and %) of the onco-proteins85 (27.33 %)
The number (and %) of the tumor suppressors41 (13.18 %)
Total number of binary PPIs (saturation %)3107 (6.45 %)
The number (and %) of affected PPIs314 (10.11 %)
The number of possible different fusions55
PPI diameter4
PPI radius2
The average degree of PPI19.235
Assortativity coefficient-0.1861
The network average Clustering coefficient0.399
The number (and %) of a zero Clustering coefficients15 (4.82 %)
The number (and %) of a zero Betweenness Centrality16 (5.14 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: RANGAP1,PPP2CA All fusions
Proteins found in more fusions EEF1G (see 1 fusions); U2AF2 (see 2 fusions); NPM1 (see 1 fusions); CUL1 (see 3 fusions); RANGAP1 (see 2 fusions); VAC14 (see 1 fusions); NUP153 (see 2 fusions); PRKDC (see 2 fusions); HDAC5 (see 1 fusions); IKBKB (see 2 fusions); EP300 (see 1 fusions); DAPK1 (see 1 fusions); PRDX6 (see 2 fusions); TPD52L2 (see 2 fusions); RPA1 (see 1 fusions); SNW1 (see 1 fusions); PTBP1 (see 1 fusions); VCP (see 4 fusions); HUWE1 (see 4 fusions); HDAC4 (see 1 fusions); PPFIA1 (see 2 fusions); PRPF8 (see 3 fusions); BAG3 (see 4 fusions); SORD (see 1 fusions); CSNK2A1 (see 2 fusions); NLK (see 4 fusions); MIB1 (see 4 fusions); NCL (see 4 fusions); RAN/CFTR (see 1 fusions); HDAC7 (see 1 fusions); CUL7 (see 2 fusions); PRKCD (see 1 fusions); CUL3 (see 1 fusions); RAC1 (see 2 fusions); CDK6 (see 1 fusions); MYC (see 2 fusions); AHCYL1 (see 2 fusions); RANBP2 (see 1 fusions); HTT (see 1 fusions); UBE2E3 (see 5 fusions); FNBP1 (see 7 fusions); PPP2R5E (see 1 fusions); FECH (see 2 fusions); SENP1 (see 1 fusions); CBX5 (see 1 fusions); LMNA (see 4 fusions); KPNB1 (see 2 fusions); PABPC1 (see 3 fusions); SGK1 (see 5 fusions); NCOA6 (see 1 fusions); EGFR (see 2 fusions); UBR5 (see 4 fusions); CBX5/UNK (see 1 fusions); PCGF2 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 RANGAP1parental protein1100.09810487.492RanGAP1_C (PF07834, IPR009109): RanGAP1 C-terminal domain
SDA1 (PF05285, IPR007949): SDA1
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
LRR_8 (PF13855, IPR001611): Leucine rich repeat
2 PPP2CAparental protein2040.06332385.249Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
3 ACTR2interactor470.288950.304Actin (PF00022, IPR004000, SM00268): Actin
4 ACTR3interactor270.390152.041Actin (PF00022, IPR004000, SM00268): Actin
5 AHCYL1suppressor120.164213.923AdoHcyase (PF05221, IPR000043, SM00996): S-adenosyl-L-homocysteine hydrolase
AdoHcyase_NAD (PF00670, IPR015878, SM00997): S-adenosyl-L-homocysteine hydrolase, NAD binding domain
DUF515 (PF04415, IPR007509): Protein of unknown function (DUF515)
Big_3_5 (PF16640, IPR032109): Bacterial Ig-like domain (group 3)
6 AHI1oncoprotein60.5333.884ArfGap (PF01412, IPR001164, SM00105): Putative GTPase activating protein for Arf
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
7 AKT1oncoprotein220.34898.082PH (PF00169, IPR001849, SM00233): PH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
8 AMBRA1interactor120.45522.920Acyl_CoA_thio (PF02551, IPR025652): Acyl-CoA thioesterase
eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Spt20 (PF12090, IPR021950): Spt20 family
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
9 ANKLE2interactor50.9000.244Cauli_VI (PF01693, IPR011320): Caulimovirus viroplasmin
LEM (PF03020, IPR003887, SM00540): LEM domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Telomere_Sde2_2 (PF13297): Telomere stability C-terminal
10 ARL2interactor60.4005.919Arf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family
11 ARPC1Binteractor180.47157.640WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
12 ARPC2interactor260.382160.054P34-Arc (PF04045, IPR007188): Arp2/3 complex, 34 kD subunit p34-Arc
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
13 ARPC4interactor230.352254.963ARPC4 (PF05856, IPR008384): ARP2/3 complex 20 kDa subunit (ARPC4)
14 ARRB2interactor290.229356.287Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
15 ATP6AP2interactor80.19087.207Phosphodiest (PF01663, IPR002591): Type I phosphodiesterase / nucleotide pyrophosphatase
Renin_r (PF07850, IPR012493): Renin receptor-like protein
16 ATP6V1Dinteractor30.33342.801ATP-synt_D (PF01813, IPR002699): ATP synthase subunit D
17 AURKBinteractor200.222165.050Pkinase (PF00069, IPR000719): Protein kinase domain
18 AXIN1suppressor100.33318.370Axin_b-cat_bind (PF08833, IPR014936): Axin beta-catenin binding domain
RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
DIX (PF00778, IPR001158, SM00021): DIX domain
AXIN1_TNKS_BD (PF16646, IPR032101): Axin-1 tankyrase binding domain
19 BABAM1interactor70.28616.371VWA_2 (PF13519, IPR002035): von Willebrand factor type A domain
20 BAG1oncoprotein160.275111.683BAG (PF02179, IPR003103, SM00264): BAG domain
Presenilin (PF01080, IPR001108): Presenilin
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
21 BAG3oncoprotein230.126384.810BAG (PF02179, IPR003103, SM00264): BAG domain
WW (PF00397, IPR001202, SM00456): WW domain
22 BCL10suppressor120.52719.644CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain
23 BCL2oncoprotein150.31984.789Bcl-2 (PF00452, IPR026298): Apoptosis regulator proteins, Bcl-2 family
BH4 (PF02180, IPR003093, SM00265): Bcl-2 homology region 4
24 BEST1interactor100Bestrophin (PF01062, IPR021134): Bestrophin, RFP-TM, chloride channel
25 BRCA1suppressor400.170769.290BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT
26 C11orf58interactor60.26740.659DUF3408 (PF11888, IPR021823): Protein of unknown function (DUF3408)
SMAP (PF15477, IPR028124): Small acidic protein family
27 CALUinteractor300.333305.696EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
28 CAMK1interactor40.6671.156Pkinase (PF00069, IPR000719): Protein kinase domain
Tyrosinase (PF00264, IPR002227): Common central domain of tyrosinase
29 CARD11oncoprotein70.6671.928CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
Cnn_1N (PF07989, IPR012943): Centrosomin N-terminal motif 1
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
zf-C4H2 (PF10146, IPR018482): Zinc finger-containing protein
Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
30 CAV1suppressor180.248128.362Caveolin (PF01146, IPR001612): Caveolin
31 CBX5suppressor160.200132.765Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
Chromo_shadow (PF01393, IPR008251, SM00300): Chromo shadow domain
32 CCDC6oncoprotein100.48915.453CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
DUF2046 (PF09755, IPR019152): Uncharacterized conserved protein H4 (DUF2046)
FAM199X (PF15814, IPR029672): Protein family FAM199X
33 CCL5interactor3013.164IL8 (PF00048, IPR001811, SM00199): Small cytokines (intecrine/chemokine), interleukin-8 like
34 CCNG2interactor30.6671.087Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
35 CCT2interactor490.385323.528Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
36 CCT3interactor470.378311.790Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
37 CCT4interactor470.384309.216Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
38 CCT5interactor480.377380.553Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
39 CCT6Ainteractor430.422204.172Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
40 CCT7interactor420.417292.607Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
41 CCT8interactor490.365348.842Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
42 CDC20oncoprotein270.345174.776WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
43 CDC27oncoprotein190.222435.931TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
44 CDC5Linteractor600.2501115.977OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component
Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
45 CDK2suppressor470.224659.428Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
46 CDK6suppressor90.42927.438Pkinase (PF00069, IPR000719): Protein kinase domain
47 CDKN2Csuppressor40.5004.089Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
48 CEP131interactor80.50041.016DASH_Spc19 (PF08287, IPR013251): Spc19
DUF342 (PF03961, IPR005646): Protein of unknown function (DUF342)
DUF743 (PF05332, IPR007996): Protein of unknown function (DUF743)
DUF826 (PF05696, IPR008544): Protein of unknown function (DUF826)
FUSC (PF04632, IPR006726): Fusaric acid resistance protein family
Histone_HNS (PF00816, IPR001801): H-NS histone family
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
UCR_hinge (PF02320, IPR023184): Ubiquinol-cytochrome C reductase hinge protein
Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR
DUF2284 (PF10050, IPR019271): Predicted metal-binding protein (DUF2284)
PRKCSH-like (PF12999, IPR028146): Glucosidase II beta subunit-like
Phage_holin_2_4 (PF16082, IPR032124): Bacteriophage holin family, superfamily II-like
49 CEP350interactor80.42911.867CAP_GLY (PF01302, IPR000938, SM01052): CAP-Gly domain
Coatamer_beta_C (PF07718, IPR011710): Coatomer beta C-terminal region
MAS20 (PF02064, IPR002056): MAS20 protein import receptor
Mucin (PF01456, IPR000458): Mucin-like glycoprotein
Topoisom_I_N (PF02919, IPR008336): Eukaryotic DNA topoisomerase I, DNA binding fragment
Complex1_LYR_2 (PF13233): Complex1_LYR-like
AAA_23 (PF13476): AAA domain
MAP17 (PF15807, IPR031627): Membrane-associated protein 117 kDa, PDZK1-interacting protein 1
50 CFTRsuppressor220.214219.457ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region
ABC_tran (PF00005, IPR003439): ABC transporter
Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
Rotamase_2 (PF13145, IPR000297): PPIC-type PPIASE domain
CFTR_R (PF14396, IPR025837): Cystic fibrosis TM conductance regulator (CFTR), regulator domain
51 CHEK2suppressor170.267215.111FHA (PF00498, IPR000253, SM00240): FHA domain
Pkinase (PF00069, IPR000719): Protein kinase domain
52 CHUKsuppressor240.368153.922Pkinase (PF00069, IPR000719): Protein kinase domain
IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain
53 CLNS1Ainteractor120.18282.713Voldacs (PF03517): Regulator of volume decrease after cellular swelling
54 COL4A3BPinteractor40.33315.616Acyl_CoA_thio (PF02551, IPR025652): Acyl-CoA thioesterase
PH (PF00169, IPR001849, SM00233): PH domain
START (PF01852, IPR002913, SM00234): START domain
55 CPSF1interactor140.45130.048CPSF_A (PF03178, IPR004871): CPSF A subunit region
MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term
HPS3_N (PF14761, IPR029437): Hermansky-Pudlak syndrome 3
56 CPSF3Linteractor130.60327.459RMMBL (PF07521, IPR011108): Zn-dependent metallo-hydrolase RNA specificity domain
Beta-Casp (PF10996, IPR022712, SM01027): Beta-Casp domain
Lactamase_B_3 (PF13483): Beta-lactamase superfamily domain
Lactamase_B_6 (PF16661, IPR001279): Metallo-beta-lactamase superfamily domain
57 CPSF4interactor70.28626.058zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
zf-CCHC (PF00098, IPR001878): Zinc knuckle
zf-CCCH_3 (PF15663): Zinc-finger containing family
58 CSNK1A1suppressor160.275147.624Pkinase (PF00069, IPR000719): Protein kinase domain
59 CSNK2A1oncoprotein350.262373.358Pkinase (PF00069, IPR000719): Protein kinase domain
60 CSNK2Binteractor320.249311.283CK_II_beta (PF01214, IPR000704, SM01085): Casein kinase II regulatory subunit
61 CTDP1interactor70.33321.745Biotin_lipoyl (PF00364, IPR000089): Biotin-requiring enzyme
FCP1_C (PF09309, IPR015388): FCP1, C-terminal
NIF (PF03031, IPR004274): NLI interacting factor-like phosphatase
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
Apt1 (PF10351, IPR019443): Golgi-body localisation protein domain
TFIIE-A_C (PF11521, IPR021600): C-terminal general transcription factor TFIIE alpha
CAF1A (PF12253, IPR022043): Chromatin assembly factor 1 subunit A
PTCB-BRCT (PF12738, IPR001357): twin BRCT domain
HlyD_D23 (PF16576, IPR032317): Barrel-sandwich domain of CusB or HlyD membrane-fusion
62 CTTNBP2interactor200.73712.651Carmo_coat_C (PF08462, IPR013669): Carmovirus coat protein
CortBP2 (PF09727, IPR019131): Cortactin-binding protein-2
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour
63 CTTNBP2NLinteractor170.78725.618CortBP2 (PF09727, IPR019131): Cortactin-binding protein-2
RBM39linker (PF15519, IPR029123): linker between RRM2 and RRM3 domains in RBM39 protein
64 CUL1suppressor430.259689.959Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
65 CUL3protein found in more fusions640.2151409.061Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
66 CUL5suppressor210.414134.845Cullin (PF00888, IPR001373, SM00182): Cullin family
GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
67 CUL7protein found in more fusions570.231827.867ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
Cullin (PF00888, IPR001373, SM00182): Cullin family
DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918)
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
68 DAPK1suppressor110.37854.525ABC_tran (PF00005, IPR003439): ABC transporter
Death (PF00531, IPR000488, SM00005): Death domain
Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase
Pkinase (PF00069, IPR000719): Protein kinase domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
AAA_23 (PF13476): AAA domain
Ank_5 (PF13857): Ankyrin repeats (many copies)
COR (PF16095, IPR032171): C-terminal of Roc, COR, domain
69 DBNLinteractor80.32126.569RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
Rrn6 (PF10214, IPR019350): RNA polymerase I-specific transcription-initiation factor
Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
SH3_9 (PF14604, IPR001452): Variant SH3 domain
70 DDTLinteractor201.075MIF (PF01187, IPR001398): Macrophage migration inhibitory factor (MIF)
71 DEC1suppressor90.7149.580DEC1 (PF15859, IPR031718): Deleted in esophageal cancer 1 family
72 DYNC1LI1interactor80.42915.240DLIC (PF05783, IPR022780): Dynein light intermediate chain (DLIC)
73 ECT2suppressor70.28644.394BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
PTCB-BRCT (PF12738, IPR001357): twin BRCT domain
PGBA_C (PF15437, IPR032737): Plasminogen-binding protein pgbA C-terminal
74 EEF1Gprotein found in more fusions240.289162.524EF1G (PF00647, IPR001662): Elongation factor 1 gamma, conserved domain
GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain
GST_N (PF02798, IPR004045): Glutathione S-transferase, N-terminal domain
SAPS (PF04499, IPR007587): SIT4 phosphatase-associated protein
75 EEF2Kinteractor80.67920.531Alpha_kinase (PF02816, IPR004166, SM00811): Alpha-kinase family
Sel1 (PF08238, IPR006597, SM00671): Sel1 repeat
76 EFL1interactor140.53876.144EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus
EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV
GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
EFG_II (PF14492, IPR009022): Elongation Factor G, domain II
77 EFTUD2interactor280.35684.810EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus
EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV
GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
EFG_II (PF14492, IPR009022): Elongation Factor G, domain II
EFTUD2 (PF16004, IPR031950): 116 kDa U5 small nuclear ribonucleoprotein component N-terminus
78 EGFRoncoprotein530.1271579.617Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
79 EP300oncoprotein290.254315.756Creb_binding (PF09030, IPR014744): Creb binding
DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902)
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
KIX (PF02172, IPR003101): KIX domain
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger
HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
80 ESPL1interactor60.40011.224Peptidase_C50 (PF03568, IPR005314): Peptidase family C50
81 ESR1suppressor440.219848.987Oest_recep (PF02159, IPR001292): Oestrogen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
82 ESRRBsuppressor50.6001.854zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
83 ETF1interactor60.4676.194eRF1_1 (PF03463, IPR005140): eRF1 domain 1
eRF1_2 (PF03464, IPR005141): eRF1 domain 2
eRF1_3 (PF03465, IPR005142): eRF1 domain 3
84 FECHprotein found in more fusions50.8330.157Ferrochelatase (PF00762, IPR001015): Ferrochelatase
85 FGFR1OPoncoprotein140.37272.434FOP_dimer (PF09398, IPR018993): FOP N terminal dimerisation domain
86 FGFR1OP2oncoprotein200.73715.979Cauli_AT (PF03233, IPR004917): Aphid transmission protein
DUF837 (PF05769, IPR008555): Protein of unknown function (DUF837)
Snapin_Pallidin (PF14712, IPR028119): Snapin/Pallidin
87 FN1oncoprotein500.214668.804fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
88 FNBP1oncoprotein4016.654FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain
HR1 (PF02185, IPR011072, SM00742): Hr1 repeat
Laminin_II (PF06009, IPR010307): Laminin Domain II
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
SH3_9 (PF14604, IPR001452): Variant SH3 domain
T3SSipB (PF16535, IPR032391): Type III cell invasion protein SipB
89 FOXB1interactor90.33313.890Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
90 FOXD4L6interactor21.0000Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
91 FOXE1oncoprotein40.3334.704Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
92 FOXJ3interactor303.943Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
PAT1 (PF09770, IPR019167): Topoisomerase II-associated protein PAT1
Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
93 FOXL1oncoprotein40.8330.330Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
94 FOXQ1interactor90.36115.956Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
95 FOXS1interactor60.20046.751Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
96 GNAI1oncoprotein50.4006.640G-alpha (PF00503, IPR001019, SM00275): G-protein alpha subunit
97 GNAI3interactor90.38930.336G-alpha (PF00503, IPR001019, SM00275): G-protein alpha subunit
98 GNL1interactor31.0000HbrB (PF08539, IPR013745): HbrB-like
MMR_HSR1 (PF01926, IPR006073): 50S ribosome-binding GTPase
Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family
99 GRNoncoprotein100.26782.906Granulin (PF00396, IPR000118, SM00277): Granulin
Lustrin_cystein (PF14625, IPR028150): Lustrin, cysteine-rich repeated domain
100 GTF3C3interactor120.258123.292BUD22 (PF09073, IPR015158): BUD22
PGA2 (PF07543, IPR011431): Protein trafficking PGA2
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
Foie-gras_1 (PF11817, IPR021773): Foie gras liver health family 1
DUF3369 (PF11849, IPR021800): Domain of unknown function (DUF3369)
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
TPR_20 (PF14561): Tetratricopeptide repeat
101 HDAC4oncoprotein130.333122.720Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
102 HDAC5protein found in more fusions440.234497.908Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NOA36 (PF06524, IPR010531): NOA36 protein
Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
103 HDAC7protein found in more fusions90.42921.500Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
PRIMA1 (PF16101): Proline-rich membrane anchor 1
CBP_BcsO (PF17037, IPR031484): Cellulose biosynthesis protein BcsO
104 HNRNPH1oncoprotein340.314312.658RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger
105 HTTprotein found in more fusions130.25868.459HEAT (PF02985, IPR000357): HEAT repeat
SPX (PF03105, IPR004331): SPX domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
DUF3652 (PF12372, IPR024613): Huntingtin protein region
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
106 HUWE1oncoprotein440.266531.110BUD22 (PF09073, IPR015158): BUD22
DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908)
DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913)
FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation
HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM)
Mucin (PF01456, IPR000458): Mucin-like glycoprotein
Nop14 (PF04147, IPR007276): Nop14-like family
PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
WWE (PF02825, IPR004170, SM00678): WWE domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)
107 ID1interactor40.5002.057HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
108 IGBP1interactor200.379104.125TAP42 (PF04177, IPR007304): TAP42-like family
109 IKBKBprotein found in more fusions200.281114.732FliT (PF05400, IPR008622): Flagellar protein FliT
Glyco_hydro_65m (PF03632, IPR005195): Glycosyl hydrolase family 65 central catalytic domain
Pkinase (PF00069, IPR000719): Protein kinase domain
SlyX (PF04102, IPR007236): SlyX
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain
110 IKBKGinteractor300.172515.192CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
DUF725 (PF05267, IPR007931): Protein of unknown function (DUF725)
NEMO (PF11577, IPR021063): NF-kappa-B essential modulator NEMO
LLC1 (PF14945, IPR020339): Normal lung function maintenance, Low in Lung Cancer 1 protein
CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
111 INTS1interactor210.405166.988DUF3677 (PF12432, IPR022145): Protein of unknown function (DUF3677)
112 INTS10interactor90.8331.615NA
113 INTS12interactor70.9050.983PHD (PF00628, IPR019787, SM00249): PHD-finger
TPPII_N (PF12583, IPR022232): Tripeptidyl peptidase II N terminal
FAM199X (PF15814, IPR029672): Protein family FAM199X
114 INTS2interactor90.77812.993INTS2 (PF14750, IPR029321): Integrator complex subunit 2
115 INTS4interactor100.86715.211Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
HEAT (PF02985, IPR000357): HEAT repeat
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
116 INTS5interactor130.73128.949INTS5_N (PF14837, IPR029445): Integrator complex subunit 5 N-terminus
INTS5_C (PF14838, IPR029444): Integrator complex subunit 5 C-terminus
117 INTS6suppressor190.439147.755VWA_2 (PF13519, IPR002035): von Willebrand factor type A domain
INT_SG_DDX_CT_C (PF15300, IPR029307): INTS6/SAGE1/DDX26B/CT45 C-terminus
DUF4596 (PF15363, IPR027907): Domain of unknown function (DUF4596)
118 INTS9interactor100.80013.885Beta-Casp (PF10996, IPR022712, SM01027): Beta-Casp domain
Lactamase_B_6 (PF16661, IPR001279): Metallo-beta-lactamase superfamily domain
119 IPO11interactor140.39660.603DUF1539 (PF07560, IPR011436): Domain of Unknown Function (DUF1539)
HEAT (PF02985, IPR000357): HEAT repeat
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
HEAT_2 (PF13646): HEAT repeats
120 IPO5interactor260.320127.242HEAT (PF02985, IPR000357): HEAT repeat
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
AAA_30 (PF13604): AAA domain
HEAT_2 (PF13646): HEAT repeats
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
121 IRAK1interactor270.332162.855Death (PF00531, IPR000488, SM00005): Death domain
Pkinase (PF00069, IPR000719): Protein kinase domain
122 ISYNA1interactor40.66714.692NAD_binding_5 (PF07994, IPR002587): Myo-inositol-1-phosphate synthase
123 ITGA4interactor420.244356.989FG-GAP (PF01839, IPR013517): FG-GAP repeat
Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region
Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
124 JUNoncoprotein180.324142.432bZIP_1 (PF00170, IPR004827): bZIP transcription factor
Jun (PF03957, IPR005643): Jun-like transcription factor
125 KDM2Ainteractor30.3333.090JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain
F-box (PF00646, IPR001810, SM00256): F-box domain
DZR (PF12773, IPR025874): Double zinc ribbon
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
LRR_8 (PF13855, IPR001611): Leucine rich repeat
PHD_4 (PF16866, IPR019787): PHD-finger
126 KIF1BPinteractor180.458111.871TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
KBP_C (PF12309, IPR022083): KIF-1 binding protein C terminal
TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat
127 KISS1Rinteractor21.00007tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
128 KLHL15interactor60.8000.881BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_3 (PF13415): Galactose oxidase, central domain
Kelch_6 (PF13964): Kelch motif
129 KNG1interactor100Bradykinin (PF06753, IPR009608): Bradykinin
Chorion_2 (PF03964, IPR005649): Chorion family 2
Cystatin (PF00031, IPR000010, SM00043): Cystatin domain
130 KPNB1protein found in more fusions490.2091237.793Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
HEAT (PF02985, IPR000357): HEAT repeat
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
V-ATPase_H_C (PF11698, IPR011987): V-ATPase subunit H
CLASP_N (PF12348, IPR024395): CLASP N terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
HEAT_EZ (PF13513): HEAT-like repeat
131 LACC1interactor100Cu-oxidase_4 (PF02578, IPR003730): Multi-copper polyphenol oxidoreductase laccase
132 LCMT1interactor30.6670.565LCM (PF04072, IPR007213): Leucine carboxyl methyltransferase
133 LMNAprotein found in more fusions320.271313.356Filament (PF00038, IPR001664): Intermediate filament protein
LTD (PF00932, IPR001322): Lamin Tail Domain
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
134 LPPoncoprotein170.265182.217LIM (PF00412, IPR001781, SM00132): LIM domain
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
135 MAP3K3oncoprotein80.4295.628PB1 (PF00564, IPR000270, SM00666): PB1 domain
Pkinase (PF00069, IPR000719): Protein kinase domain
136 MAPK3oncoprotein160.248110.486Pkinase (PF00069, IPR000719): Protein kinase domain
137 MDC1suppressor220.325161.515FHA (PF00498, IPR000253, SM00240): FHA domain
DUF3274 (PF11678, IPR021692): Protein of unknown function (DUF3274)
Yop-YscD_cpl (PF16697, IPR032030): Inner membrane component of T3SS, cytoplasmic domain
RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
138 MEPCEinteractor170.338101.880Bin3 (PF06859, IPR010675): Bicoid-interacting protein 3 (Bin3)
Methyltransf_23 (PF13489): Methyltransferase domain
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
DLEU7 (PF15760, IPR031510): Leukemia-associated protein 7
139 MIB1protein found in more fusions80.33377.130Ank (PF00023, IPR002110, SM00248): Ankyrin repeat
MIB_HERC2 (PF06701, IPR010606): Mib_herc2
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
140 MID1oncoprotein110.244100.645Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
141 MMS19interactor220.195307.465DUF3437 (PF11919, IPR021843): Domain of unknown function (DUF3437)
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
HEAT_2 (PF13646): HEAT repeats
MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
142 MOB4interactor310.497148.411Mob1_phocein (PF03637, IPR005301): Mob1/phocein family
143 MRPS26interactor80.39321.609MRP-S26 (PF14943, IPR026140): Mitochondrial ribosome subunit S26
144 MYConcoprotein540.221945.986HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain
Myc_N (PF01056, IPR012682): Myc amino-terminal region
145 MYH9suppressor330.235434.925IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
146 MYO18Ainteractor90.50016.119Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
147 NCLprotein found in more fusions420.261416.586DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
Myc_N (PF01056, IPR012682): Myc amino-terminal region
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
YL1 (PF05764, IPR008895): YL1 nuclear protein
Limkain-b1 (PF11608, IPR024582): Limkain b1
148 NCOA6oncoprotein90.42951.167DUF719 (PF05334, IPR007998): Protein of unknown function (DUF719)
Fes1 (PF08609, IPR013918): Nucleotide exchange factor Fes1
Presenilin (PF01080, IPR001108): Presenilin
DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729)
Nucleic_acid_bd (PF13820, IPR032715): Putative nucleic acid-binding region
NST1 (PF13945, IPR025279): Salt tolerance down-regulator
149 NDUFA7interactor30.3334.389CI-B14_5a (PF07347, IPR009947): NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a)
150 NIF3L1interactor220.410519.087NIF3 (PF01784, IPR002678): NIF3 (NGG1p interacting factor 3)
151 NLKprotein found in more fusions60.4008.326Pkinase (PF00069, IPR000719): Protein kinase domain
SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
152 NOSIPinteractor50.9000.157Rtf2 (PF04641, IPR027799): Rtf2 RING-finger
U-box (PF04564, IPR003613, SM00504): U-box domain
zf-NOSIP (PF15906, IPR031790): Zinc-finger of nitric oxide synthase-interacting protein
153 NOTCH1suppressor250.221179.434Ank (PF00023, IPR002110, SM00248): Ankyrin repeat
EGF (PF00008, IPR000742, SM00181): EGF-like domain
EGF_2 (PF07974, IPR013111): EGF-like domain
EGF_alliinase (PF04863, IPR006947): Alliinase EGF-like domain
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
NOD (PF06816, IPR010660): NOTCH protein
NODP (PF07684, IPR011656): NOTCH protein
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
Notch (PF00066, IPR000800, SM00004): LNR domain
DUF3454 (PF11936, IPR024600): Domain of unknown function (DUF3454)
hEGF (PF12661, IPR013032): Human growth factor-like EGF
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
154 NPM1suppressor500.280870.310Nucleoplasmin (PF03066): Nucleoplasmin/nucleophosmin domain
SDA1 (PF05285, IPR007949): SDA1
NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain
155 NPTX1interactor100IncA (PF04156, IPR007285): IncA protein
MRP-S27 (PF10037, IPR019266): Mitochondrial 28S ribosomal protein S27
Pentaxin (PF00354, IPR001759, SM00159): Pentaxin family
156 NRDCinteractor70.40021.613Cnd2 (PF05786, IPR022816): Condensin complex subunit 2
Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16)
Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain
Tom22 (PF04281, IPR005683): Mitochondrial import receptor subunit Tom22
Peptidase_M16_M (PF16187, IPR032632): Middle or third domain of peptidase_M16
157 NSUN2interactor290.264519.849Methyltr_RsmB-F (PF01189, IPR001678): 16S rRNA methyltransferase RsmB/F
158 NTRK1oncoprotein1170.1117562.035I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
159 NUBP2interactor50.4009.519ParA (PF10609, IPR019591): NUBPL iron-transfer P-loop NTPase
160 NUP107interactor260.425281.580Nup84_Nup100 (PF04121, IPR007252): Nuclear pore protein 84 / 107
161 NUP153protein found in more fusions290.376222.222Nup153 (PF08604, IPR013913): Nucleoporin Nup153-like
Nup_retrotrp_bd (PF10599, IPR018892): Retro-transposon transporting motif
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
Nucleoporin_FG (PF13634, IPR025574): Nucleoporin FG repeat region
162 NUP35interactor110.6916.510Nup35_RRM (PF05172, IPR007846): Nup53/35/40-type RNA recognition motif
163 NUP85interactor130.59030.867Nucleopor_Nup85 (PF07575, IPR011502): Nup85 Nucleoporin
164 NXF1interactor640.1102215.807NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding
TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
165 OBSL1interactor490.258513.953BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
166 OSGEPinteractor170.61723.120Peptidase_M22 (PF00814, IPR000905): Glycoprotease family
167 PABPC1oncoprotein340.280282.832RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain
YflT (PF11181, IPR025889): Heat induced stress protein YflT
168 PANK4interactor140.59359.057DUF89 (PF01937, IPR002791): Protein of unknown function DUF89
Fumble (PF03630, IPR004567): Fumble
169 PAXIP1interactor180.235171.426BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
IPT (PF01745, IPR002648, SM00429): Isopentenyl transferase
SURF6 (PF04935, IPR007019): Surfeit locus protein 6
DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052)
CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
PTCB-BRCT (PF12738, IPR001357): twin BRCT domain
BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
LIG3_BRCT (PF16759, IPR031916): DNA ligase 3 BRCT domain
RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
170 PCF11interactor90.30628.197CTD_bind (PF04818, IPR006903): RNA polymerase II-binding domain.
zf-DBF (PF07535, IPR006572, SM00586): DBF zinc finger
CFIA_Pcf11 (PF11526, IPR021605): Subunit of cleavage factor IA Pcf11
171 PCGF2suppressor60.6002.962zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
172 PCM1oncoprotein170.235166.901FliD_N (PF02465, IPR003481): Flagellar hook-associated protein 2 N-terminus
FUSC (PF04632, IPR006726): Fusaric acid resistance protein family
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein
Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family
RseA_C (PF03873, IPR005573): Anti sigma-E protein RseA, C-terminal domain
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
V_ATPase_I (PF01496, IPR002490): V-type ATPase 116kDa subunit family
AAA_23 (PF13476): AAA domain
zf-C4pol (PF14260, IPR025687): C4-type zinc-finger of DNA polymerase delta
PCM1_C (PF15717, IPR031446): Pericentriolar material 1 C terminus
DUF4829 (PF16111, IPR032256): Domain of unknown function (DUF4829)
173 PDCD10interactor250.52394.828DUF1241 (PF06840, IPR009652): Protein of unknown function (DUF1241)
CENP-L (PF13092, IPR025204): Kinetochore complex Sim4 subunit Fta1
174 PFDN1interactor60.40018.365Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit
175 PIM1oncoprotein70.33314.600Pkinase (PF00069, IPR000719): Protein kinase domain
176 PIN1suppressor230.206384.358Rotamase (PF00639, IPR000297): PPIC-type PPIASE domain
WW (PF00397, IPR001202, SM00456): WW domain
177 PIRinteractor40.3338.857Pirin (PF02678, IPR003829): Pirin
Pirin_C (PF05726, IPR008778): Pirin C-terminal cupin domain
178 PKN3interactor31.0000HR1 (PF02185, IPR011072, SM00742): Hr1 repeat
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
179 PMS1oncoprotein100.55618.667DNA_mis_repair (PF01119, IPR013507): DNA mismatch repair protein, C-terminal domain
HTH_Tnp_IS630 (PF01710, IPR002622): Transposase
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
MRP-L46 (PF11788, IPR021757): 39S mitochondrial ribosomal protein L46
HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
180 PMS2oncoprotein100.17835.651DNA_mis_repair (PF01119, IPR013507): DNA mismatch repair protein, C-terminal domain
MORN_2 (PF07661, IPR011652): MORN repeat variant
MutL_C (PF08676, IPR014790, SM00853): MutL C terminal dimerisation domain
HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
181 PNPT1interactor80.6792.911PNPase (PF03726, IPR015848): Polyribonucleotide nucleotidyltransferase, RNA binding domain
RNase_PH (PF01138, IPR001247): 3' exoribonuclease family, domain 1
RNase_PH_C (PF03725, IPR015847): 3' exoribonuclease family, domain 2
S1 (PF00575, IPR003029, SM00316): S1 RNA binding domain
KH_1 (PF00013, IPR004088, SM00322): KH domain
182 POLA1interactor110.32722.792DNA_pol_B (PF00136, IPR006134): DNA polymerase family B
DNA_pol_B_exo1 (PF03104, IPR006133): DNA polymerase family B, exonuclease domain
zf-DNA_Pol (PF08996, IPR015088): DNA Polymerase alpha zinc finger
DNA_pol_alpha_N (PF12254, IPR024647): DNA polymerase alpha subunit p180 N terminal
183 POLR3Cinteractor40.5002.892HTH_9 (PF08221, IPR013197): RNA polymerase III subunit RPC82 helix-turn-helix domain
NIT (PF08376, IPR013587): Nitrate and nitrite sensing
RNA_pol_Rpc82 (PF05645, IPR008806): RNA polymerase III subunit RPC82
HD_4 (PF13328, IPR003607): HD domain
184 PPATinteractor40.5006.439Pribosyltran (PF00156, IPR000836): Phosphoribosyl transferase domain
GATase_6 (PF13522): Glutamine amidotransferase domain
185 PPFIA1protein found in more fusions130.37942.373HWE_HK (PF07536, IPR011102, SM00911): HWE histidine kinase
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
BLOC1_2 (PF10046, IPR019269): Biogenesis of lysosome-related organelles complex-1 subunit 2
Cluap1 (PF10234, IPR019366): Clusterin-associated protein-1
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
Cep57_CLD_2 (PF14197, IPR025925): Centrosome localisation domain of PPC89
DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472)
TSNAXIP1_N (PF15739, IPR032755): Translin-associated factor X-interacting N-terminus
FAM76 (PF16046, IPR032017): FAM76 protein
CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour
186 PPFIA2interactor60.8004.138DUF745 (PF05335, IPR007999): Protein of unknown function (DUF745)
HrpB7 (PF09486, IPR013392): Bacterial type III secretion protein (HrpB7)
HWE_HK (PF07536, IPR011102, SM00911): HWE histidine kinase
IFP_35_N (PF07334, IPR009938): Interferon-induced 35 kDa protein (IFP 35) N-terminus
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
SlyX (PF04102, IPR007236): SlyX
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
BLOC1_2 (PF10046, IPR019269): Biogenesis of lysosome-related organelles complex-1 subunit 2
CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour
187 PPFIA3interactor60.9000.561DUF745 (PF05335, IPR007999): Protein of unknown function (DUF745)
T2SSF (PF00482, IPR018076): Type II secretion system (T2SS), protein F
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
Tup_N (PF08581, IPR013890): Tup N-terminal
FTA4 (PF13093, IPR025207): Kinetochore complex Fta4 of Sim4 subunit, or CENP-50
FAM76 (PF16046, IPR032017): FAM76 protein
188 PPIBinteractor100.31136.931Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
189 PPIFinteractor2017.795Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
190 PPM1Binteractor100.40019.865PP2C (PF00481, IPR001932): Protein phosphatase 2C
PP2C_C (PF07830, IPR012911, SM00332): Protein serine/threonine phosphatase 2C, C-terminal domain
191 PPME1interactor180.309197.091Abhydrolase_6 (PF12697, IPR000073): Alpha/beta hydrolase family
192 PPP2CBsuppressor770.1632212.826Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
193 PPP2R1Aoncoprotein980.1084436.941TAF6_C (PF07571, IPR011442): TAF6 C-terminal HEAT repeat domain
HEAT (PF02985, IPR000357): HEAT repeat
HEAT_PBS (PF03130, IPR004155, SM00567): PBS lyase HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
194 PPP2R1Bsuppressor450.198618.474HEAT (PF02985, IPR000357): HEAT repeat
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_2 (PF13646): HEAT repeats
195 PPP2R2Ainteractor290.404166.126WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Y_phosphatase2 (PF03162, IPR004861): Tyrosine phosphatase family
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
196 PPP2R2Binteractor210.50057.152WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
197 PPP2R2Csuppressor190.50943.996WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
198 PPP2R2Dinteractor230.455122.877WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Y_phosphatase2 (PF03162, IPR004861): Tyrosine phosphatase family
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
199 PPP2R3Ainteractor50.7001.982EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
DUF3924 (PF13062, IPR025038): Protein of unknown function (DUF3924)
DUF4116 (PF13475, IPR025197): Domain of unknown function (DUF4116)
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
DUF4187 (PF13821, IPR025239): Domain of unknown function (DUF4187)
200 PPP2R3Binteractor41.0000EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
201 PPP2R5Ainteractor160.34260.774B56 (PF01603, IPR002554): Protein phosphatase 2A regulatory B subunit (B56 family)
202 PPP2R5Binteractor50.4005.450B56 (PF01603, IPR002554): Protein phosphatase 2A regulatory B subunit (B56 family)
203 PPP2R5Csuppressor150.314269.462B56 (PF01603, IPR002554): Protein phosphatase 2A regulatory B subunit (B56 family)
DUF1616 (PF07760, IPR011674): Protein of unknown function (DUF1616)
204 PPP2R5Dinteractor250.280554.965B56 (PF01603, IPR002554): Protein phosphatase 2A regulatory B subunit (B56 family)
205 PPP2R5Eprotein found in more fusions150.363114.288B56 (PF01603, IPR002554): Protein phosphatase 2A regulatory B subunit (B56 family)
206 PPP4Cinteractor260.406152.025Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
207 PPP4R1interactor80.6794.766HEAT (PF02985, IPR000357): HEAT repeat
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_2 (PF13646): HEAT repeats
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
208 PRDX6protein found in more fusions150.22061.894AhpC-TSA (PF00578, IPR000866): AhpC/TSA family
1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin
209 PRKAA1suppressor100.37814.746Pkinase (PF00069, IPR000719): Protein kinase domain
AdenylateSensor (PF16579, IPR032270): Adenylate sensor of SNF1-like protein kinase
210 PRKCDsuppressor100.4725.936Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
211 PRKDCprotein found in more fusions480.233765.781FAT (PF02259, IPR003151): FAT domain
FATC (PF02260, IPR003152): FATC domain
NUC194 (PF08163, IPR012582): NUC194 domain
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
212 PRPF8oncoprotein320.368157.044PRO8NT (PF08082, IPR012591): PRO8NT (NUC069), PrP8 N-terminal domain
PROCN (PF08083, IPR012592): PROCN (NUC071) domain
PROCT (PF08084, IPR012984): PROCT (NUC072) domain
RRM_4 (PF10598, IPR019582): RNA recognition motif of the spliceosomal PrP8
U5_2-snRNA_bdg (PF10597, IPR019581): U5-snRNA binding site 2 of PrP8
U6-snRNA_bdg (PF10596, IPR019580): U6-snRNA interacting domain of PrP8
JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
PRP8_domainIV (PF12134, IPR021983): PRP8 domain IV core
213 PRR14interactor40.8330.363CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Tantalus (PF15386, IPR028149): Drosophila Tantalus-like
214 PRR14Linteractor31.0000Tantalus (PF15386, IPR028149): Drosophila Tantalus-like
215 PSMC6interactor190.333164.061AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
AAA_2 (PF07724, IPR013093): AAA domain (Cdc48 subfamily)
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
Prot_ATP_ID_OB (PF16450, IPR032501): Proteasomal ATPase OB/ID domain
216 PSMD1interactor170.40468.274PA26 (PF04636, IPR006730): PA26 p53-induced protein (sestrin)
PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat
HEAT_2 (PF13646): HEAT repeats
217 PSMD3interactor190.287153.880Rpn3_C (PF08375, IPR013586): Proteasome regulatory subunit C-terminal
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
PCI (PF01399, IPR000717, SM00088): PCI domain
Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat
TSKS (PF15358, IPR028214): Testis-specific serine kinase substrate
218 PTBP1oncoprotein260.34394.384RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
219 PTNoncoprotein50.50053.660PTN_MK_C (PF01091, IPR020090): PTN/MK heparin-binding protein family, C-terminal domain
PTN_MK_N (PF05196, IPR020089): PTN/MK heparin-binding protein family, N-terminal domain
220 PTPAsuppressor220.299131.696PTPA (PF03095, IPR004327): Phosphotyrosyl phosphate activator (PTPA) protein
221 PXNoncoprotein70.5717.260LIM (PF00412, IPR001781, SM00132): LIM domain
Paxillin (PF03535): Paxillin family
222 PYGMinteractor100Phosphorylase (PF00343, IPR000811): Carbohydrate phosphorylase
223 RAC1oncoprotein120.40019.087Ras (PF00071, IPR001806, SM00173): Ras family
224 RAF1oncoprotein250.239273.421Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
RBD (PF02196, IPR003116, SM00455): Raf-like Ras-binding domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
225 RALAoncoprotein60.26763.277ArgK (PF03308, IPR005129): ArgK protein
Ras (PF00071, IPR001806, SM00173): Ras family
ThiF (PF00899, IPR000594): ThiF family
226 RALYinteractor230.364275.245RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SelK_SelG (PF10961, IPR024491): Selenoprotein SelK_SelG
227 RANoncoprotein270.333210.564Ras (PF00071, IPR001806, SM00173): Ras family
228 RANBP2oncoprotein390.300529.889Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
Ran_BP1 (PF00638, IPR000156, SM00160): RanBP1 domain
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
DUF2693 (PF10902, IPR024401): Protein of unknown function (DUF2693)
IR1-M (PF12185, IPR022011): Nup358/RanBP2 E3 ligase domain
Dmrt1 (PF12374, IPR022114): Double-sex mab3 related transcription factor 1
TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
229 RBL2suppressor70.4296.718CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Pap_E4 (PF02711, IPR003861): E4 protein
RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain
RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain
SLH (PF00395, IPR001119): S-layer homology domain
TFIIB (PF00382, IPR013150): Transcription factor TFIIB repeat
DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452)
230 RBPJinteractor120.24297.780BTD (PF09270, IPR015350): Beta-trefoil DNA-binding domain
LAG1-DNAbind (PF09271, IPR015351): LAG1, DNA binding
TIG (PF01833, IPR002909): IPT/TIG domain
231 RCC1interactor230.336233.998RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat
RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
232 RELAoncoprotein260.293634.272DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
233 RGPD2interactor100GRIP (PF01465, IPR000237, SM00755): GRIP domain
HemX (PF04375, IPR007470): HemX, putative uroporphyrinogen-III C-methyltransferase
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
Tropomyosin (PF00261, IPR000533): Tropomyosin
Ran_BP1 (PF00638, IPR000156, SM00160): RanBP1 domain
Med21 (PF11221, IPR021384): Subunit 21 of Mediator complex
TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat
TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
Rab_bind (PF16704, IPR032023): Rab binding domain
234 RGPD5interactor40.6672.985GRIP (PF01465, IPR000237, SM00755): GRIP domain
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
Ran_BP1 (PF00638, IPR000156, SM00160): RanBP1 domain
TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
FlxA (PF14282, IPR025577): FlxA-like protein
TPR_19 (PF14559): Tetratricopeptide repeat
Rab_bind (PF16704, IPR032023): Rab binding domain
235 RGPD6interactor100GRIP (PF01465, IPR000237, SM00755): GRIP domain
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
Ran_BP1 (PF00638, IPR000156, SM00160): RanBP1 domain
TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
FlxA (PF14282, IPR025577): FlxA-like protein
TPR_19 (PF14559): Tetratricopeptide repeat
Rab_bind (PF16704, IPR032023): Rab binding domain
236 RNF2interactor350.193481.003zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
237 RORConcoprotein70.66740.386zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
238 RP9interactor21.0000Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein
Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
239 RPA1suppressor470.265513.402Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain
Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain
240 RPA2oncoprotein410.216819.847RPA_C (PF08784, IPR014892): Replication protein A C terminal
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2
241 RPA3interactor350.246388.136Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3
242 RPRD1Binteractor210.305163.687CTD_bind (PF04818, IPR006903): RNA polymerase II-binding domain.
Efg1 (PF10153, IPR019310): rRNA-processing protein Efg1
CTK3 (PF12243, IPR024638): CTD kinase subunit gamma CTK3
CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour
243 RPS6KB2interactor220.31270.640Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
244 SAE1interactor150.305107.765ThiF (PF00899, IPR000594): ThiF family
245 SCARNA22interactor80.4296.702NA
246 SEH1Linteractor190.42166.739WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
Ge1_WD40 (PF16529, IPR032401): WD40 region of Ge1, enhancer of mRNA-decapping protein
247 SENP1protein found in more fusions110.48921.764Peptidase_C48 (PF02902, IPR003653): Ulp1 protease family, C-terminal catalytic domain
248 SENP2interactor50.60012.719Peptidase_C48 (PF02902, IPR003653): Ulp1 protease family, C-terminal catalytic domain
249 SERTAD4interactor90.6943.695SERTA (PF06031, IPR009263): SERTA motif
DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446)
250 SETBP1oncoprotein305.651AT_hook (PF02178, IPR017956, SM00384): AT hook motif
251 SGK1oncoprotein60.6001.856Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
PX (PF00787, IPR001683, SM00312): PX domain
252 SGO1interactor50.7000.849DUF778 (PF05608, IPR008496): Protein of unknown function (DUF778)
Menin (PF05053, IPR007747): Menin
Shugoshin_C (PF07557, IPR011515): Shugoshin C terminus
Shugoshin_N (PF07558, IPR011516): Shugoshin N-terminal coiled-coil region
253 SGO2interactor40.5008.340DivIC (PF04977, IPR007060): Septum formation initiator
Shugoshin_C (PF07557, IPR011515): Shugoshin C terminus
VitD-bind_III (PF09164, IPR015247): Vitamin D binding protein, domain III
Tox-SHH (PF15652, IPR028900): HNH/Endo VII superfamily toxin with a SHH signature
254 SH3GLB1suppressor180.50749.456BAR (PF03114, IPR004148, SM00721): BAR domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
255 SIK2interactor80.5009.111Pkinase (PF00069, IPR000719): Protein kinase domain
256 SIKE1interactor170.9122.281DUF837 (PF05769, IPR008555): Protein of unknown function (DUF837)
Rho_Binding (PF08912, IPR015008): Rho Binding
257 SIRT7interactor440.235445.516DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563)
SIR2 (PF02146, IPR003000): Sir2 family
258 SLMAPinteractor170.84610.353Fez1 (PF06818): Fez1
FHA (PF00498, IPR000253, SM00240): FHA domain
Spectrin (PF00435, IPR002017): Spectrin repeat
DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472)
Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease
T3SSipB (PF16535, IPR032391): Type III cell invasion protein SipB
DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
259 SMURF1interactor230.260130.186C2 (PF00168, IPR000008, SM00239): C2 domain
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
260 SNW1protein found in more fusions560.244955.500SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
SIR4_SID (PF16991, IPR031556): Sir4 SID domain
261 SOD1interactor90.214264.094Sod_Cu (PF00080, IPR001424): Copper/zinc superoxide dismutase (SODC)
262 SORDprotein found in more fusions70.26742.495ADH_N (PF08240, IPR013154): Alcohol dehydrogenase GroES-like domain
ADH_zinc_N (PF00107, IPR013149): Zinc-binding dehydrogenase
ADH_zinc_N_2 (PF13602): Zinc-binding dehydrogenase
263 SOX2oncoprotein270.092570.966HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
SOXp (PF12336, IPR022097): SOX transcription factor
264 SPRY2suppressor60.40032.191KAR9 (PF08580, IPR013889): Yeast cortical protein KAR9
Sprouty (PF05210, IPR007875): Sprouty protein (Spry)
265 SSBinteractor160.36746.322HMA (PF00403, IPR006121): Heavy-metal-associated domain
La (PF05383, IPR006630, SM00715): La domain
Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family
Ribosomal_L6e (PF01159, IPR000915): Ribosomal protein L6e
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RRM_3 (PF08777, IPR014886): RNA binding motif
266 STK24interactor300.59491.291DUF1241 (PF06840, IPR009652): Protein of unknown function (DUF1241)
Pkinase (PF00069, IPR000719): Protein kinase domain
267 STK25interactor200.77923.747DUF1241 (PF06840, IPR009652): Protein of unknown function (DUF1241)
Pkinase (PF00069, IPR000719): Protein kinase domain
268 STK26interactor220.64847.109DUF1241 (PF06840, IPR009652): Protein of unknown function (DUF1241)
Pkinase (PF00069, IPR000719): Protein kinase domain
269 STRIP1interactor210.695113.610ELM2 (PF01448, IPR000949): ELM2 domain
N1221 (PF07923, IPR012486): N1221-like protein
DUF3402 (PF11882, IPR021819): Domain of unknown function (DUF3402)
270 STRIP2interactor150.8861.887N1221 (PF07923, IPR012486): N1221-like protein
DUF3402 (PF11882, IPR021819): Domain of unknown function (DUF3402)
271 STRNoncoprotein320.526145.093CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
Nucleoporin_N (PF08801, IPR014908): Nup133 N terminal like
Striatin (PF08232, IPR013258): Striatin family
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
272 STRN3interactor310.563148.633Striatin (PF08232, IPR013258): Striatin family
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
273 STRN4interactor230.557150.054CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
Striatin (PF08232, IPR013258): Striatin family
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
274 SUB1interactor130.19765.560Dehydrin (PF00257, IPR000167): Dehydrin
PC4 (PF02229, IPR003173): Transcriptional Coactivator p15 (PC4)
275 SUMO1interactor240.292258.303Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like
276 SUPT5Hinteractor210.295112.239KOW (PF00467, IPR005824, SM00739): KOW motif
Ribonuc_P_40 (PF08584, IPR013893): Ribonuclease P 40kDa (Rpp40) subunit
Spt5-NGN (PF03439, IPR005100): Early transcription elongation factor of RNA pol II, NGN section
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
DUF3912 (PF13051, IPR025023): Protein of unknown function (DUF3912)
277 TBCDinteractor50.5009.195HEAT (PF02985, IPR000357): HEAT repeat
HEAT_PBS (PF03130, IPR004155, SM00567): PBS lyase HEAT-like repeat
TFCD_C (PF12612, IPR022577): Tubulin folding cofactor D C terminal
HEAT_EZ (PF13513): HEAT-like repeat
278 TCP1interactor440.420250.391Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
279 TERF1interactor210.137456.922TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF)
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
280 THG1Linteractor110.60015.992Thg1 (PF04446, IPR024956): tRNAHis guanylyltransferase
Thg1C (PF14413, IPR025845): Thg1 C terminal domain
281 TIPRLinteractor90.38952.498TIP41 (PF04176, IPR007303): TIP41-like family
282 TLX1oncoprotein21.0000Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal
283 TMUB1interactor30.3332.740DUF347 (PF03988, IPR007136): Repeat of Unknown Function (DUF347)
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
DUF4227 (PF14004, IPR025321): Protein of unknown function (DUF4227)
284 TNPO1interactor170.309232.693Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
HEAT (PF02985, IPR000357): HEAT repeat
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
DUF3437 (PF11919, IPR021843): Domain of unknown function (DUF3437)
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
285 TNPO3interactor130.37249.633HEAT (PF02985, IPR000357): HEAT repeat
IFRD (PF05004, IPR007701): Interferon-related developmental regulator (IFRD)
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
286 TOPORSsuppressor31.0000Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif
Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
287 TP53RKoncoprotein170.61027.478APH (PF01636, IPR002575): Phosphotransferase enzyme family
Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
288 TPD52L2protein found in more fusions250.330222.426TPD52 (PF04201, IPR007327): Tumour protein D52 family
289 TPRKBinteractor190.49754.008CGI-121 (PF08617, IPR013926): Kinase binding protein CGI-121
290 TRAF3IP3interactor150.7815.552ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
FUSC (PF04632, IPR006726): Fusaric acid resistance protein family
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
291 TRIP13interactor150.28675.640AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
292 TUBA8interactor308.079Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
293 TWIST1oncoprotein50.5009.335ACC_epsilon (PF13822, IPR032716): Acyl-CoA carboxylase epsilon subunit
PRR20 (PF15708, IPR031439): Proline-rich protein family 20
FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2
294 U2AF2protein found in more fusions330.423125.334RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Transformer (PF06495, IPR010519): Fruit fly transformer protein
295 UBE2E3protein found in more fusions110.111120.322UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
296 UBE2Iinteractor400.211887.863UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
297 UBR4interactor120.19753.043CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Pheromone (PF08015, IPR012597): Fungal mating-type pheromone
RecR (PF02132, IPR023628): RecR protein
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box)
DZR (PF12773, IPR025874): Double zinc ribbon
E3_UbLigase_R4 (PF13764, IPR025704): E3 ubiquitin-protein ligase UBR4
FAM176 (PF14851): FAM176 family
298 UBR5protein found in more fusions180.243143.919CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
SDA1 (PF05285, IPR007949): SDA1
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain
E3_UbLigase_EDD (PF11547, IPR024725): E3 ubiquitin ligase EDD
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein
299 UFM1interactor120.37988.651Ufm1 (PF03671, IPR005375): Ubiquitin fold modifier 1 protein
300 UNC5Bsuppressor40.6673.441Death (PF00531, IPR000488, SM00005): Death domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
SKG6 (PF08693, IPR014805): Transmembrane alpha-helix domain
ZU5 (PF00791, IPR000906, SM00218): ZU5 domain
TSP_1 (PF00090, IPR000884, SM00209): Thrombospondin type 1 domain
Ig_3 (PF13927): Immunoglobulin domain
UPA (PF17217): UPA domain
301 UNKprotein found in more fusions220.264213.613MbeD_MobD (PF04899, IPR006983): MbeD/MobD like
NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
zf-CCCH_2 (PF14608): RNA-binding, Nab2-type zinc finger
Torus (PF16131, IPR032297): Torus domain
302 USP7oncoprotein290.214487.135MATH (PF00917, IPR002083, SM00061): MATH domain
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
USP7_ICP0_bdg (PF12436, IPR024729): ICP0-binding domain of Ubiquitin-specific protease 7
USP7_C2 (PF14533, IPR029346): Ubiquitin-specific protease C-terminal
303 USPL1interactor40.5001.905zinc_ribbon_2 (PF13240, IPR026870): zinc-ribbon domain
Peptidase_C98 (PF15499, IPR028890): Ubiquitin-specific peptidase-like, SUMO isopeptidase
DUF4650 (PF15509, IPR029388): Domain of unknown function (DUF4650)
304 VAC14oncoprotein50.6672.092TAF6_C (PF07571, IPR011442): TAF6 C-terminal HEAT repeat domain
HEAT (PF02985, IPR000357): HEAT repeat
Vac14_Fig4_bd (PF11916, IPR021841): Vacuolar protein 14 C-terminal Fig4p binding
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
305 VCAM1interactor380.226296.701C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
306 VCPprotein found in more fusions650.1911858.199AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2
CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain
TniB (PF05621, IPR008868): Bacterial TniB protein
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
307 XPO1interactor780.1163216.238CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
308 XRN1interactor120.36427.253XRN_N (PF03159, IPR004859): XRN 5'-3' exonuclease N-terminus
309 ZFP36suppressor90.25028.928zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
310 ZNF114interactor60.7001.882HNH (PF01844, IPR002711): HNH endonuclease
KRAB (PF01352, IPR001909, SM00349): KRAB box
PKI (PF02827, IPR004171): cAMP-dependent protein kinase inhibitor
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
311 ZNF346interactor204.449zf-U1 (PF06220, IPR013085, SM00451): U1 zinc finger
Vps39_2 (PF10367, IPR019453): Vacuolar sorting protein 39 domain 2
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
zf-met (PF12874): Zinc-finger of C2H2 type

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