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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins RALGPS2, SLC22A17 (from a repository: Fri Mar 17 03:44:39 2017)

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)7
The number (and %) of the onco-proteins3 (42.86 %)
The number (and %) of the tumor suppressors1 (14.29 %)
Total number of binary PPIs (saturation %)18 (85.71 %)
The number (and %) of affected PPIs5 (27.78 %)
The number of possible different fusions4
PPI diameter3
PPI radius2
The average degree of PPI4.000
Assortativity coefficient-0.2839
The network average Clustering coefficient0.657
The number (and %) of a zero Clustering coefficients1 (14.29 %)
The number (and %) of a zero Betweenness Centrality1 (14.29 %)


List of the fusions

PPI for parental proteins: RALGPS2,SLC22A17 All fusions
Proteins found in more fusions MCM2 (see 1 fusions); YWHAG (see 1 fusions); YWHAZ (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Domains (Pfam, InterPro, SMART): description
1 RALGPS2parental protein40.8330.500PH (PF00169, IPR001849, SM00233): PH domain
RasGEF (PF00617, IPR001895, SM00147): RasGEF domain
2 SLC22A17parental protein100Sugar_tr (PF00083, IPR005828): Sugar (and other) transporter
3 MCM2oncoprotein60.50010.500AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
4 SFNsuppressor50.8331.00014-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
5 YWHABinteractor40.8331.00014-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
Virulence_fact (PF13769, IPR025989): Virulence factor
6 YWHAGprotein found in more fusions60.8001.50014-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
7 YWHAZprotein found in more fusions60.8001.50014-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein

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