Find Fusion Network

Visualization interactions

Powered by Cytoscape Web for: parental proteins NRDE2, TMIGD3 (from a repository: Sun Aug 18 04:10:51 2019)

Examples AFF1 MLL ACTN4 + MLLAFF1 + MLLALK + MSNALK + TFGALK + TPM3ALK + TPM4ASXL2 + KAT6AATF1 + FUSBCR + ABL1BCR + FGFR1CCND1 + TACSTD2CD74 + ROS1CDK6 + MLLCOL1A1 + PDGFBCREB3L2 + PPARGCREB3L2 + FUSCREBBP + KAT6ADAZAP1 + MEF2DELL + MLLEPS15 + MLLERG + EWSR1ERG + FUSERG + TMPRSS2ETV5 + TMPRSS2ETV6 + ABL1ETV6 + NTRK3ETV6 + PAX5EWSR1 + FLI1EWSR1 + WT1FOXO1 + PAX3FOXP1 + PAX5FRYL + MLLGAS7 + MLLGMPS + MLLGOLGA5 + RETHOOK3 + RETHOXC13 + NUP98HOXD13 + NUP98MECOM + RUNX1MKL1 + RBM15MLL + MLLT1MLL + MLLT4MLL + MLLT10MLL + PICALMMLLT10 + PICALMNCOA1 + PAX3NIN + PDGFRBNPM1 + RARANRG1 + ODZ4NTRK1 + TFGNUMA1 + RARANUP98 + PHF23PAX5 + ZNF521PBX1 + TCF3RET + TRIM27ROS1 + SLC34A2PML + RARAPRKAR1A + RARAPRKAR1A + RETRUNX1 + RUNX1T1RUNX1 + SH3D19	Cytoscape Web will replace the contents your graph	PPI Properties: Click on nodes or edges
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Statistics and Network structure information

Statistic of PPI Value(s) The number of interactors (fusion and proteins) 5 The number (and %) of the onco-proteins 0 (0.00 %) The number (and %) of the tumor suppressors 1 (20.00 %) Total number of binary PPIs (saturation %) 5 (50.00 %) The number (and %) of affected PPIs 3 (60.00 %) The number of possible different fusions 1 PPI diameter 2 PPI radius inf The average degree of PPI 1.600 Assortativity coefficient -0.3333 The network average Clustering coefficient 0.467 The number (and %) of a zero Clustering coefficients 2 (40.00 %) The number (and %) of a zero Betweenness Centrality 4 (80.00 %)

ACTIVE INTERACTORS

List of the fusions
PPI for parental proteins: NRDE2,TMIGD3	All fusions
Proteins found in more fusions

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	NRDE2	parental protein	3	0.333	4.000	NRDE-2 (PF08424, IPR013633): NRDE-2, necessary for RNA interference TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat NPR3 (PF03666, IPR005365): Nitrogen Permease regulator of amino acid transport activity 3 TPR_14 (PF13428): Tetratricopeptide repeat AP3D1 (PF06375): AP-3 complex subunit delta-1
2	TMIGD3	interactor	0	0	0	NA
3	EED	suppressor	3	1.000	0	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
4	RNPS1	interactor	1	0	0	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457) Macoilin (PF09726, IPR019130): Transmembrane protein
5	RPS10	interactor	2	1.000	0	S10_plectin (PF03501, IPR005326): Plectin/S10 domain

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