Find Fusion Network

Enter
Fusion ID:
Protein names:


Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins RBM47, NREP (from a repository: Sat Jul 20 17:10:56 2019)
Examples

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Circle
Radial
Force Directed
Preset
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)11
The number (and %) of the onco-proteins3 (27.27 %)
The number (and %) of the tumor suppressors2 (18.18 %)
Total number of binary PPIs (saturation %)20 (36.36 %)
The number (and %) of affected PPIs11 (55.00 %)
The number of possible different fusions3
PPI diameter4
PPI radius2
The average degree of PPI2.545
Assortativity coefficient-0.2178
The network average Clustering coefficient0.221
The number (and %) of a zero Clustering coefficients6 (54.55 %)
The number (and %) of a zero Betweenness Centrality5 (45.45 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: RBM47,NREP All fusions
Proteins found in more fusions MAGED1 (see 1 fusions); EEF1A1 (see 6 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 RBM47parental protein50.20026.000Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
2 NREPparental protein60.06753.000DUF2719 (PF10891, IPR020122): Protein of unknown function (DUF2719)
Alveol-reg_P311 (PF11092, IPR024417): Neuronal protein 3.1 (p311)
3 ATMsuppressor40.6678.000FAT (PF02259, IPR003151): FAT domain
FATC (PF02260, IPR003152): FATC domain
HEAT (PF02985, IPR000357): HEAT repeat
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
TAN (PF11640, IPR021668): Telomere-length maintenance and DNA damage repair
ANAPC5 (PF12862, IPR026000): Anaphase-promoting complex subunit 5
4 C1orf94interactor305.000DUF4688 (PF15752, IPR031496): Domain of unknown function (DUF4688)
5 EEF1A1suppressor200GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
6 ELAVL1oncoprotein50.50018.000RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
7 HSFY1interactor100HSF_DNA-bind (PF00447, IPR000232, SM00415): HSF-type DNA-binding
8 IGSF21interactor100C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
9 KMT2Boncoprotein100FLO_LFY (PF01698, IPR002910): Floricaula / Leafy protein
FYRC (PF05965, IPR003889, SM00542): F/Y rich C-terminus
FYRN (PF05964, IPR003888, SM00541): F/Y-rich N-terminus
GRP (PF07172, IPR010800): Glycine rich protein family
PHD (PF00628, IPR019787, SM00249): PHD-finger
SET (PF00856, IPR001214, SM00317): SET domain
zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
Fer4_2 (PF12797, IPR001450): 4Fe-4S binding domain
zf-HC5HC2H (PF13771): PHD-like zinc-binding domain
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3
10 MAGED1protein found in more fusions308.000MAGE (PF01454, IPR002190): MAGE family
11 RNF2interactor31.0000zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like

B a c k    t o    T o p ⇑