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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)117
The number (and %) of the onco-proteins35 (29.91 %)
The number (and %) of the tumor suppressors17 (14.53 %)
Total number of binary PPIs (saturation %)1079 (15.90 %)
The number (and %) of affected PPIs120 (11.12 %)
The number of possible different fusions28
PPI diameter4
PPI radius2
The average degree of PPI17.778
Assortativity coefficient-0.0982
The network average Clustering coefficient0.485
The number (and %) of a zero Clustering coefficients5 (4.27 %)
The number (and %) of a zero Betweenness Centrality7 (5.98 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: SERBP1,TMCO1 All fusions
Proteins found in more fusions U2AF2 (see 2 fusions); NPM1 (see 1 fusions); CUL1 (see 3 fusions); CUL3 (see 1 fusions); GRB2 (see 1 fusions); PARK2 (see 1 fusions); KAT2B (see 1 fusions); PIAS1 (see 3 fusions); RPL37A/RPS24 (see 1 fusions); TP53 (see 3 fusions); APP (see 5 fusions); ABCC1 (see 1 fusions); RPS24/RPS23 (see 1 fusions); SFPQ (see 6 fusions); SFN (see 1 fusions); HUWE1 (see 4 fusions); PABPC1 (see 3 fusions); SERBP1 (see 1 fusions); ATP5A1/HUWE1 (see 2 fusions); NF2 (see 1 fusions); MCM2 (see 1 fusions); CSNK2A1 (see 2 fusions); CHD3 (see 1 fusions); ATP5A1 (see 1 fusions); VIM (see 1 fusions); RPS19/RPS14 (see 1 fusions); TRIM29 (see 3 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 SERBP1parental protein860.1933352.903HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family
FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
2 TMCO1parental protein340.201865.687DUF106 (PF01956, IPR002809): Integral membrane protein DUF106
3 ABCC1oncoprotein70.46765.007ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region
ABC_tran (PF00005, IPR003439): ABC transporter
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
ABC_ATPase (PF09818, IPR019195): Predicted ATPase of the ABC class
DUF2304 (PF10066, IPR019277): Uncharacterized conserved protein (DUF2304)
DUF4131 (PF13567, IPR025405): Domain of unknown function (DUF4131)
4 AFG3L2interactor140.50547.001AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
FtsH_ext (PF06480, IPR011546): FtsH Extracellular
Peptidase_M41 (PF01434, IPR000642): Peptidase family M41
TniB (PF05621, IPR008868): Bacterial TniB protein
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
5 AHSA1interactor220.429173.070Aha1_N (PF09229, IPR015310, SM01000): Activator of Hsp90 ATPase, N-terminal
AHSA1 (PF08327, IPR013538): Activator of Hsp90 ATPase homolog 1-like protein
6 APPprotein found in more fusions260.360191.905APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
7 ARRB2interactor180.42549.043Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
8 ATP1A1interactor230.395150.071Cation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus
Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus
E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
Tetraspannin (PF00335, IPR018499): Tetraspanin family
Cation_ATPase (PF13246): Cation transport ATPase (P-type)
9 ATP5A1protein found in more fusions330.304439.395ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain
ATP-synt_ab_C (PF00306, IPR000793): ATP synthase alpha/beta chain, C terminal domain
ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain
10 ATP5F1interactor60.6675.763Mt_ATP-synt_B (PF05405, IPR008688): Mitochondrial ATP synthase B chain precursor (ATP-synt_B)
DUF2105 (PF09878, IPR019212): Predicted membrane protein (DUF2105)
11 ATXN3interactor60.10019.057Josephin (PF02099, IPR006155): Josephin
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
12 BASP1suppressor60.6005.690BASP1 (PF05466, IPR008408): Brain acid soluble protein 1 (BASP1 protein)
13 CAND1interactor380.453220.429Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981)
HEAT (PF02985, IPR000357): HEAT repeat
TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20)
RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
14 CD81interactor160.62910.489Tetraspannin (PF00335, IPR018499): Tetraspanin family
15 CENPAinteractor60.4009.502Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
16 CHD3oncoprotein80.6193.857CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain
CHDNT (PF08073, IPR012958): CHDNT (NUC034) domain
Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
DUF1086 (PF06461, IPR009462, SM01146): Domain of Unknown Function (DUF1086)
DUF1087 (PF06465, IPR009463, SM01147): Domain of Unknown Function (DUF1087)
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
PHD (PF00628, IPR019787, SM00249): PHD-finger
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SMN (PF06003, IPR010304): Survival motor neuron protein (SMN)
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
DUF2956 (PF11169, IPR021339): Protein of unknown function (DUF2956)
FAM176 (PF14851): FAM176 family
17 CLTConcoprotein270.316256.899Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker
Clathrin_propel (PF01394, IPR022365): Clathrin propeller repeat
Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS
Clathrin_H_link (PF13838): Clathrin-H-link
18 CSNK2A1oncoprotein210.363105.572Pkinase (PF00069, IPR000719): Protein kinase domain
19 CTNNB1oncoprotein140.45121.020Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361)
HEAT_EZ (PF13513): HEAT-like repeat
20 CUL1suppressor360.462131.398Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
21 CUL3protein found in more fusions480.345436.338Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
22 CYC1interactor130.66714.850Cytochrom_C1 (PF02167, IPR002326): Cytochrome C1 family
23 DAXXoncoprotein60.6002.764Daxx (PF03344, IPR005012): Daxx N-terminal Rassf1C-interacting domain
Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM)
Nop14 (PF04147, IPR007276): Nop14-like family
RF-1 (PF00472, IPR000352): RF-1 domain
Vpu (PF00558, IPR008187): Vpu protein
DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391)
24 DDX39Ainteractor100.33353.480DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
25 DYNC1H1interactor130.47424.378AAA_5 (PF07728, IPR011704): AAA domain (dynein-related subfamily)
DHC_N1 (PF08385, IPR013594): Dynein heavy chain, N-terminal region 1
DHC_N2 (PF08393, IPR013602): Dynein heavy chain, N-terminal region 2
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948)
Dynein_heavy (PF03028, IPR004273): Dynein heavy chain and region D6 of dynein motor
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
AAA_6 (PF12774): Hydrolytic ATP binding site of dynein motor region D1
AAA_7 (PF12775): P-loop containing dynein motor region D3
MT (PF12777, IPR024743): Microtubule-binding stalk of dynein motor
AAA_8 (PF12780, IPR024317): P-loop containing dynein motor region D4
AAA_9 (PF12781): ATP-binding dynein motor region D5
26 DYNC1I2interactor70.6676.254Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052)
Dynein_IC2 (PF11540, IPR025956): Cytoplasmic dynein 1 intermediate chain 2
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
DUF4329 (PF14220, IPR025479): Domain of unknown function (DUF4329)
27 DYNC1LI1interactor60.8673.684DLIC (PF05783, IPR022780): Dynein light intermediate chain (DLIC)
28 DYNLT3interactor70.6003.430Tctex-1 (PF03645, IPR005334): Tctex-1 family
29 EIF2Ainteractor100.6224.884Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like
eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
30 ELAVL1oncoprotein320.224545.514RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
31 ESR1suppressor320.383156.164Oest_recep (PF02159, IPR001292): Oestrogen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
32 FAUinteractor200.64716.820Ribosomal_S30 (PF04758, IPR006846): Ribosomal protein S30
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
33 FBXO25suppressor100.51110.877Elongin_A (PF06881, IPR010684): RNA polymerase II transcription factor SIII (Elongin) subunit A
34 FBXO6interactor300.262346.364FBA (PF04300, IPR007397): F-box associated region
F-box-like (PF12937, IPR001810): F-box-like
35 FBXW7suppressor50.5007.698Mem_trans (PF03547, IPR004776): Membrane transport protein
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
F-box-like (PF12937, IPR001810): F-box-like
36 FUSsuppressor260.41591.321Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
Limkain-b1 (PF11608, IPR024582): Limkain b1
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
37 FXYD3interactor100ATP1G1_PLM_MAT8 (PF02038, IPR000272): ATP1G1/PLM/MAT8 family
38 FYTTD1interactor200FYTT (PF07078, IPR009782): Forty-two-three protein
39 GARSinteractor50.40032.575HGTP_anticodon (PF03129, IPR004154): Anticodon binding domain
tRNA-synt_2b (PF00587, IPR002314): tRNA synthetase class II core domain (G, H, P, S and T)
WHEP-TRS (PF00458, IPR000738, SM00991): WHEP-TRS domain
40 GRB2oncoprotein160.51422.265SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093)
41 HIST1H3Einteractor110.63612.928Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
42 HNRNPRinteractor210.50551.269RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Limkain-b1 (PF11608, IPR024582): Limkain b1
43 HNRNPUinteractor450.385352.722CDC45 (PF02724, IPR003874): CDC45-like protein
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SAP (PF02037, IPR003034, SM00513): SAP domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
AAA_33 (PF13671): AAA domain
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
44 HSD17B12interactor160.51754.738adh_short (PF00106, IPR002198): short chain dehydrogenase
45 HUWE1oncoprotein290.47698.018BUD22 (PF09073, IPR015158): BUD22
DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908)
DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913)
FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation
HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM)
Mucin (PF01456, IPR000458): Mucin-like glycoprotein
Nop14 (PF04147, IPR007276): Nop14-like family
PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
WWE (PF02825, IPR004170, SM00678): WWE domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)
46 ISG15suppressor110.36415.116ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
47 ITFG1interactor200.883FG-GAP (PF01839, IPR013517): FG-GAP repeat
K1 (PF02960, IPR004121): K1 glycoprotein
VCBS (PF13517): Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella
48 KAT2Bprotein found in more fusions80.38122.850Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family
PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
49 KIF14oncoprotein40.3331.822FHA (PF00498, IPR000253, SM00240): FHA domain
LMBR1 (PF04791, IPR006876): LMBR1-like membrane protein
Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14
SdrG_C_C (PF10425, IPR011266): C-terminus of bacterial fibrinogen-binding adhesin
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
Gluconate_2-dh3 (PF13618, IPR027056): Gluconate 2-dehydrogenase subunit 3
Kinesin_assoc (PF16183, IPR032405): Kinesin-associated
50 KPNA3interactor40.3334.309Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
IBB (PF01749, IPR002652): Importin beta binding domain
Arm_3 (PF16186, IPR032413): Atypical Arm repeat
51 LAMTOR3interactor40.3338.372MAPKK1_Int (PF08923, IPR015019): Mitogen-activated protein kinase kinase 1 interacting
52 MAP1LC3Ainteractor60.3336.900Atg8 (PF02991, IPR004241): Autophagy protein Atg8 ubiquitin like
53 MAP4oncoprotein80.4644.797SdiA-regulated (PF06977, IPR009722): SdiA-regulated
Tubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeat
DUF3275 (PF11679, IPR021693): Protein of unknown function (DUF3275)
54 MCM2oncoprotein430.344430.350AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
55 MDC1suppressor90.50022.004FHA (PF00498, IPR000253, SM00240): FHA domain
DUF3274 (PF11678, IPR021692): Protein of unknown function (DUF3274)
Yop-YscD_cpl (PF16697, IPR032030): Inner membrane component of T3SS, cytoplasmic domain
RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
56 NEDD8interactor180.46365.469ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
57 NF2suppressor70.53310.115ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
58 NPM1suppressor500.410334.189Nucleoplasmin (PF03066): Nucleoplasmin/nucleophosmin domain
SDA1 (PF05285, IPR007949): SDA1
NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain
59 NTRK1oncoprotein560.2281096.134I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
60 OTUB1interactor120.45532.388Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain
61 PA2G4interactor120.5458.003Peptidase_M24 (PF00557, IPR001714): Metallopeptidase family M24
Ribosomal_S25 (PF03297, IPR004977): S25 ribosomal protein
TraC (PF07820, IPR012930): TraC-like protein
62 PABPC1oncoprotein300.411161.113RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain
YflT (PF11181, IPR025889): Heat induced stress protein YflT
63 PAN2interactor230.56143.641RNase_T (PF00929, IPR013520): Exonuclease
UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase
WD40_like (PF17005, IPR031544): WD40-like domain
64 PARK2suppressor240.42398.105IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
65 PCAPoncoprotein100NA
66 PDHBinteractor80.32126.536Transket_pyr (PF02779, IPR005475, SM00861): Transketolase, pyrimidine binding domain
Transketolase_C (PF02780, IPR005476): Transketolase, C-terminal domain
67 PIAS1suppressor60.8000.917Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein
zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger
PINIT (PF14324, IPR023321): PINIT domain
UPF0544 (PF15749, IPR032739): Uncharacterised protein family UPF0544
68 PIAS3oncoprotein21.0000SAP (PF02037, IPR003034, SM00513): SAP domain
zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger
PINIT (PF14324, IPR023321): PINIT domain
69 PIAS4interactor70.5717.953CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
SAP (PF02037, IPR003034, SM00513): SAP domain
zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger
PINIT (PF14324, IPR023321): PINIT domain
70 PPP2R1Aoncoprotein200.45872.213TAF6_C (PF07571, IPR011442): TAF6 C-terminal HEAT repeat domain
HEAT (PF02985, IPR000357): HEAT repeat
HEAT_PBS (PF03130, IPR004155, SM00567): PBS lyase HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
71 PRMT8interactor50.6670.365PrmA (PF06325, IPR010456): Ribosomal protein L11 methyltransferase (PrmA)
72 RAB1Aoncoprotein130.55125.968Ras (PF00071, IPR001806, SM00173): Ras family
73 RAB1Boncoprotein100.62212.867Ras (PF00071, IPR001806, SM00173): Ras family
74 RPL10suppressor310.60069.748Ribosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e
75 RPL37Aprotein found in more fusions250.73015.275Ribosomal_L37ae (PF01780, IPR002674): Ribosomal L37ae protein family
76 RPL4interactor360.53094.859Ribosomal_L4 (PF00573, IPR002136): Ribosomal protein L4/L1 family
Ribos_L4_asso_C (PF14374, IPR025755): 60S ribosomal protein L4 C-terminal domain
77 RPN1oncoprotein270.359255.446Ribophorin_I (PF04597, IPR007676): Ribophorin I
CtIP_N (PF10482, IPR019518): Tumour-suppressor protein CtIP N-terminal domain
78 RPS10interactor340.542167.116S10_plectin (PF03501, IPR005326): Plectin/S10 domain
79 RPS14protein found in more fusions340.60648.650Ribosomal_S11 (PF00411, IPR001971): Ribosomal protein S11
80 RPS19protein found in more fusions360.53387.899Ribosomal_S19e (PF01090, IPR001266): Ribosomal protein S19e
81 RPS20interactor320.57168.765Ribosomal_S10 (PF00338, IPR027486): Ribosomal protein S10p/S20e
82 RPS23protein found in more fusions310.62439.101Ribosom_S12_S23 (PF00164, IPR006032): Ribosomal protein S12/S23
83 RPS24protein found in more fusions300.66433.147Fascin (PF06268, IPR022768): Fascin domain
Ribosomal_S24e (PF01282, IPR001976): Ribosomal protein S24e
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
84 RPS25interactor340.60258.105Ribosomal_S25 (PF03297, IPR004977): S25 ribosomal protein
85 RPS26interactor250.66732.828Ribosomal_S26e (PF01283, IPR000892): Ribosomal protein S26e
86 RPS29interactor190.78418.234Ribosomal_S14 (PF00253, IPR001209): Ribosomal protein S14p/S29e
87 RPS3interactor400.500163.053KH_2 (PF07650, IPR004044): KH domain
Ribosomal_S3_C (PF00189, IPR001351): Ribosomal protein S3, C-terminal domain
88 RPS6interactor370.529115.195Ribosomal_S6e (PF01092, IPR001377): Ribosomal protein S6e
DUF4574 (PF15141, IPR027896): Domain of unknown function (DUF4574)
89 RPS6KB2interactor160.45041.093Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
90 SERINC1interactor100Serinc (PF03348, IPR005016): Serine incorporator (Serinc)
91 SFNsuppressor200.59616.88314-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
92 SFPQoncoprotein220.32486.172GRP (PF07172, IPR010800): Glycine rich protein family
Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
NOPS (PF08075, IPR012975): NOPS (NUC059) domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
PAT1 (PF09770, IPR019167): Topoisomerase II-associated protein PAT1
CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
93 SIRT7interactor300.340182.328DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563)
SIR2 (PF02146, IPR003000): Sir2 family
94 SLC25A3interactor230.391151.111Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
95 SRSF5interactor130.56418.371DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
96 SSR3interactor90.50012.899TRAP-gamma (PF07074, IPR009779): Translocon-associated protein, gamma subunit (TRAP-gamma)
97 TARDBPinteractor300.55754.120RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
98 TCTN2interactor70.6677.252DUF1619 (PF07773, IPR011677): Protein of unknown function (DUF1619)
99 TCTN3interactor90.50029.683DUF1619 (PF07773, IPR011677): Protein of unknown function (DUF1619)
100 TDGinteractor31.0000Pox_Ag35 (PF03286, IPR004966): Pox virus Ag35 surface protein
UDG (PF03167, IPR005122, SM00986): Uracil DNA glycosylase superfamily
101 TDRD3interactor40.6670.268RMI1_N (PF08585, IPR013894, SM01161): RecQ mediated genome instability protein
TUDOR (PF00567, IPR002999, SM00333): Tudor domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
DUF3472 (PF11958, IPR021862): Domain of unknown function (DUF3472)
102 TERToncoprotein40.8330.720RVT_1 (PF00078, IPR000477): Reverse transcriptase (RNA-dependent DNA polymerase)
Telomerase_RBD (PF12009, IPR021891, SM00975): Telomerase ribonucleoprotein complex - RNA binding domain
103 TMEM63Binteractor70.5248.636RSN1_7TM (PF02714, IPR003864): Calcium-dependent channel, 7TM region, putative phosphate
Wzy_C (PF04932, IPR007016): O-Antigen ligase
DUF4006 (PF13179, IPR025065): Family of unknown function (DUF4006)
RSN1_TM (PF13967, IPR032880): Late exocytosis, associated with Golgi transport
PHM7_cyt (PF14703, IPR027815): Cytosolic domain of 10TM putative phosphate transporter
104 TOPORSsuppressor30.6670.267Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif
Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
105 TP53suppressor390.300393.495DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
106 TRIM29protein found in more fusions70.6002.483MIS13 (PF08202, IPR013218): Mis12-Mtw1 protein family
TP2 (PF01254, IPR000678): Nuclear transition protein 2
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
107 TSR1interactor220.71485.659AARP2CN (PF08142, IPR012948, SM00785): AARP2CN (NUC121) domain
RIBIOP_C (PF04950, IPR007034): 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal
NUSAP (PF16006, IPR026756): Nucleolar and spindle-associated protein
108 U2AF2protein found in more fusions240.54938.230RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Transformer (PF06495, IPR010519): Fruit fly transformer protein
109 UBA2interactor30.6670.307ThiF (PF00899, IPR000594): ThiF family
UAE_UbL (PF14732, IPR028077): Ubiquitin/SUMO-activating enzyme ubiquitin-like domain
UBA2_C (PF16195, IPR032426): SUMO-activating enzyme subunit 2 C-terminus
110 UNC93B1interactor40.5002.444UNC-93 (PF05978, IPR010291): Ion channel regulatory protein UNC-93
Ndc1_Nup (PF09531, IPR019049): Nucleoporin protein Ndc1-Nup
DUF4131 (PF13567, IPR025405): Domain of unknown function (DUF4131)
111 UPF2interactor70.6671.136DDHD (PF02862, IPR004177, SM01127): DDHD domain
DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
MIF4G (PF02854, IPR003890, SM00543): MIF4G domain
Upf2 (PF04050, IPR007193): Up-frameshift suppressor 2
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
SUFU_C (PF12470, IPR024314): Suppressor of Fused Gli/Ci N terminal binding domain
112 UQCRC2oncoprotein180.45173.944Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16)
Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain
113 UQCRQinteractor110.47323.391UcrQ (PF02939, IPR004205): UcrQ family
114 VAV2oncoprotein41.0000PH (PF00169, IPR001849, SM00233): PH domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
CAMSAP_CH (PF11971, IPR022613): CAMSAP CH domain
CotJB (PF12652, IPR024207): CotJB protein
115 VIMsuppressor220.229115.621Filament (PF00038, IPR001664): Intermediate filament protein
Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region
116 WDR5interactor90.5287.350WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
117 YIPF5interactor60.40014.242Yip1 (PF04893, IPR006977): Yip1 domain

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