Find Fusion Network

Enter
Fusion ID:
Protein names:


Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins ATAD2B, ATG2B (from a repository: Wed Jun 14 08:14:53 2017)
Examples

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Circle
Radial
Force Directed
Preset
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)14
The number (and %) of the onco-proteins2 (14.29 %)
The number (and %) of the tumor suppressors1 (7.14 %)
Total number of binary PPIs (saturation %)20 (21.98 %)
The number (and %) of affected PPIs12 (60.00 %)
The number of possible different fusions1
PPI diameter2
PPI radiusinf
The average degree of PPI2.714
Assortativity coefficient-0.5487
The network average Clustering coefficient0.485
The number (and %) of a zero Clustering coefficients5 (35.71 %)
The number (and %) of a zero Betweenness Centrality10 (71.43 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: ATG2B,ATAD2B All fusions
Proteins found in more fusions

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 ATG2Bparental protein110.12784.000ATG_C (PF09333, IPR015412): Autophagy-related protein C terminal domain
Chorein_N (PF12624, IPR026854): N-terminal region of Chorein or VPS13
ATG2_CAD (PF13329, IPR026885): Autophagy-related protein 2 CAD motif
VPS13 (PF16908, IPR031646): Vacuolar sorting-associated protein 13, N-terminal
VPS13_C (PF16909, IPR031645): Vacuolar-sorting-associated 13 protein C-terminal
2 ATAD2Bparental protein100AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
AAA_18 (PF13238): AAA domain
AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3
3 ATG2Ainteractor21.0000ATG_C (PF09333, IPR015412): Autophagy-related protein C terminal domain
Chorein_N (PF12624, IPR026854): N-terminal region of Chorein or VPS13
ATG2_CAD (PF13329, IPR026885): Autophagy-related protein 2 CAD motif
VPS13_C (PF16909, IPR031645): Vacuolar-sorting-associated 13 protein C-terminal
4 CEP89interactor30.6671.000ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
CorA (PF01544, IPR002523): CorA-like Mg2+ transporter protein
Exonuc_VII_L (PF02601, IPR020579): Exonuclease VII, large subunit
Lectin_N (PF03954, IPR005640): Hepatic lectin, N-terminal domain
Spc24 (PF08286, IPR013252): Spc24 subunit of Ndc80
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
5 HDAC11interactor100Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
6 LHX6suppressor21.0000BON (PF04972, IPR007055, SM00749): BON domain
LIM (PF00412, IPR001781, SM00132): LIM domain
zf-dskA_traR (PF01258, IPR000962): Prokaryotic dksA/traR C4-type zinc finger
DUF2175 (PF09943, IPR018686): Uncharacterized protein conserved in archaea (DUF2175)
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
7 MED4interactor21.0000Med4 (PF10018, IPR019258): Vitamin-D-receptor interacting Mediator subunit 4
8 MLF1oncoprotein100Mlf1IP (PF10248, IPR019376): Myelodysplasia-myeloid leukemia factor 1-interacting protein
9 NTRK1oncoprotein31.0000I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
10 POC1Ainteractor21.0000WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
11 SIRT7interactor100DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563)
SIR2 (PF02146, IPR003000): Sir2 family
12 TALDO1interactor30.6671.000TAL_FSA (PF00923, IPR001585): Transaldolase/Fructose-6-phosphate aldolase
13 WDR45interactor60.33310.000CNH (PF00780, IPR001180, SM00036): CNH domain
DUF1736 (PF08409, IPR013618): Domain of unknown function (DUF1736)
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
14 ZSCAN26interactor100C1_4 (PF07975, IPR004595, SM01047): TFIIH C1-like domain
SCAN (PF02023, IPR003309, SM00431): SCAN domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain

B a c k    t o    T o p ⇑