1 |
DNAJC10 | parental protein | 32 | 0.250 | 697.254 | DnaJ (PF00226, IPR001623, SM00271): DnaJ domain Thioredoxin (PF00085, IPR013766): Thioredoxin Thioredoxin_6 (PF13848): Thioredoxin-like domain |
2 |
DPYD | parental protein | 9 | 0 | 465.905 | DHO_dh (PF01180, IPR012135): Dihydroorotate dehydrogenase Pyr_redox_2 (PF07992, IPR023753): Pyridine nucleotide-disulphide oxidoreductase Fer4_8 (PF13183, IPR017896): 4Fe-4S dicluster domain Fer4_20 (PF14691, IPR028261): Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_21 (PF14697): 4Fe-4S dicluster domain |
3 |
C9orf64 | interactor | 3 | 0 | 57.681 | Q_salvage (PF10343, IPR019438): Potential Queuosine, Q, salvage protein family |
4 |
CAND1 | interactor | 17 | 0.792 | 22.572 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981) HEAT (PF02985, IPR000357): HEAT repeat TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20) RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II |
5 |
CDC42 | oncoprotein | 5 | 0.667 | 3.797 | Ras (PF00071, IPR001806, SM00173): Ras family |
6 |
CHAC2 | interactor | 1 | 0 | 0 | ChaC (PF04752, IPR006840): ChaC-like protein |
7 |
CLK1 | interactor | 4 | 0.333 | 56.886 | PDGF_N (PF04692, IPR006782): Platelet-derived growth factor, N terminal region Pkinase (PF00069, IPR000719): Protein kinase domain |
8 |
COPS5 | protein found in more fusions | 18 | 0.816 | 23.744 | JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease |
9 |
CUL1 | suppressor | 16 | 0.819 | 22.601 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
10 |
CUL2 | suppressor | 14 | 0.868 | 17.462 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
11 |
CUL3 | protein found in more fusions | 20 | 0.667 | 91.022 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal |
12 |
CUL4A | protein found in more fusions | 15 | 0.736 | 20.818 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
13 |
CUL4B | oncoprotein | 15 | 0.838 | 18.991 | Cullin (PF00888, IPR001373, SM00182): Cullin family EBP50_C (PF09007, IPR015098): EBP50, C-terminal Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain PG_binding_4 (PF12229, IPR022029): Putative peptidoglycan binding domain MDFI (PF15316, IPR026134): MyoD family inhibitor |
14 |
CUL5 | suppressor | 16 | 0.850 | 3.366 | Cullin (PF00888, IPR001373, SM00182): Cullin family GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
15 |
DCUN1D1 | interactor | 13 | 0.936 | 0.786 | Cullin_binding (PF03556, IPR005176): Cullin binding UBA_4 (PF14555): UBA-like domain |
16 |
EDEM1 | interactor | 1 | 0 | 0 | Glyco_hydro_47 (PF01532, IPR001382): Glycosyl hydrolase family 47 |
17 |
ESRRB | suppressor | 3 | 0.333 | 11.766 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
18 |
FOXRED2 | interactor | 1 | 0 | 0 | Pyr_redox_3 (PF13738): Pyridine nucleotide-disulphide oxidoreductase |
19 |
FUS | suppressor | 17 | 0.816 | 22.149 | Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others Limkain-b1 (PF11608, IPR024582): Limkain b1 FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head |
20 |
GAN | protein found in more fusions | 4 | 1.000 | 0 | BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif Kelch_3 (PF13415): Galactose oxidase, central domain Kelch_5 (PF13854): Kelch motif |
21 |
GAPDH | oncoprotein | 14 | 0.590 | 358.370 | Gp_dh_C (PF02800, IPR020829): Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N (PF00044, IPR020828, SM00846): Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain OstA (PF03968, IPR005653): OstA-like protein |
22 |
GOPC | oncoprotein | 2 | 0 | 0 | DUF903 (PF06004, IPR010305): Bacterial protein of unknown function (DUF903) HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper DUF3209 (PF11483, IPR021577): Protein of unknown function (DUF3209) |
23 |
HNRNPA1 | interactor | 20 | 0.608 | 106.437 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1 |
24 |
HSPA4 | interactor | 10 | 0.911 | 0.632 | Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region HSP70 (PF00012, IPR013126): Hsp70 protein TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5 |
25 |
HSPA4L | interactor | 3 | 1.000 | 0 | HSP70 (PF00012, IPR013126): Hsp70 protein |
26 |
HSPA5 | oncoprotein | 23 | 0.506 | 111.306 | HSP70 (PF00012, IPR013126): Hsp70 protein |
27 |
IFI16 | suppressor | 3 | 0.667 | 0.667 | HIN (PF02760, IPR004021): HIN-200/IF120x domain PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain Mitofilin (PF09731, IPR019133): Mitochondrial inner membrane protein |
28 |
LXN | suppressor | 1 | 0 | 0 | Latexin (PF06907, IPR009684): Latexin |
29 |
MAGEA11 | interactor | 2 | 0 | 0 | MAGE (PF01454, IPR002190): MAGE family MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal |
30 |
MCM2 | oncoprotein | 12 | 0.709 | 27.879 | AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
31 |
NAXE | interactor | 1 | 0 | 0 | YjeF_N (PF03853, IPR004443): YjeF-related protein N-terminus |
32 |
NEDD8 | interactor | 16 | 0.714 | 64.402 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
33 |
NTRK1 | oncoprotein | 19 | 0.582 | 124.043 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
34 |
PCSK9 | interactor | 1 | 0 | 0 | Peptidase_S8 (PF00082, IPR000209): Subtilase family Inhibitor_I9 (PF05922, IPR010259): Peptidase inhibitor I9 |
35 |
RPE | interactor | 2 | 0 | 0 | OMPdecase (PF00215, IPR001754, SM00934): Orotidine 5'-phosphate decarboxylase / HUMPS family Ribul_P_3_epim (PF00834, IPR000056): Ribulose-phosphate 3 epimerase family |
36 |
SFTPC | protein found in more fusions | 4 | 1.000 | 0 | BRICHOS (PF04089, IPR007084, SM01039): BRICHOS domain SP_C-Propep (PF08999, IPR015091): Surfactant protein C, N terminal propeptide |
37 |
SMURF2 | protein found in more fusions | 2 | 0 | 0 | C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) |
38 |
TCF3 | suppressor | 2 | 0 | 0 | CDC45 (PF02724, IPR003874): CDC45-like protein HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain DUF3682 (PF12446, IPR022152): Protein of unknown function (DUF3682) |
39 |
TCTN1 | interactor | 2 | 1.000 | 0 | DUF1619 (PF07773, IPR011677): Protein of unknown function (DUF1619) |
40 |
TCTN3 | interactor | 2 | 1.000 | 0 | DUF1619 (PF07773, IPR011677): Protein of unknown function (DUF1619) |
41 |
TRNT1 | interactor | 1 | 0 | 0 | PolyA_pol (PF01743, IPR002646): Poly A polymerase head domain PolyA_pol_RNAbd (PF12627, IPR032828): Probable RNA and SrmB- binding site of polymerase A |
42 |
TXNL1 | interactor | 2 | 1.000 | 0 | PITH (PF06201, IPR010400): PITH domain Thioredoxin (PF00085, IPR013766): Thioredoxin |
43 |
VCP | protein found in more fusions | 15 | 0.725 | 15.464 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2 CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain TniB (PF05621, IPR008868): Bacterial TniB protein Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944) |