1 |
DNAJC10 | parental protein | 32 | 0.250 | 668.523 | DnaJ (PF00226, IPR001623, SM00271): DnaJ domain Thioredoxin (PF00085, IPR013766): Thioredoxin Thioredoxin_6 (PF13848): Thioredoxin-like domain |
2 |
TRIM71 | parental protein | 7 | 0.095 | 234.495 | DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755) Filamin (PF00630, IPR017868): Filamin/ABP280 repeat NHL (PF01436, IPR001258): NHL repeat FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger DUF4094 (PF13334, IPR025298): Domain of unknown function (DUF4094) zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain DUF5128 (PF17170): 6-bladed beta-propeller |
3 |
AGO2 | interactor | 10 | 0.511 | 164.196 | ArgoL1 (PF08699, IPR014811, SM01163): Argonaute linker 1 domain PAZ (PF02170, IPR003100, SM00949): PAZ domain Piwi (PF02171, IPR003165, SM00950): Piwi domain ArgoN (PF16486, IPR032474): N-terminal domain of argonaute ArgoMid (PF16487, IPR032473): Mid domain of argonaute ArgoL2 (PF16488, IPR032472): Argonaute linker 2 domain |
4 |
CAND1 | interactor | 17 | 0.767 | 21.044 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981) HEAT (PF02985, IPR000357): HEAT repeat TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20) RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II |
5 |
CDC42 | oncoprotein | 5 | 0.667 | 1.667 | Ras (PF00071, IPR001806, SM00173): Ras family |
6 |
COPS5 | protein found in more fusions | 19 | 0.706 | 94.629 | JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease |
7 |
CUL1 | suppressor | 16 | 0.800 | 19.353 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
8 |
CUL2 | suppressor | 14 | 0.835 | 17.701 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
9 |
CUL3 | protein found in more fusions | 20 | 0.661 | 74.145 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal |
10 |
CUL4A | protein found in more fusions | 17 | 0.575 | 86.047 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
11 |
CUL4B | oncoprotein | 14 | 0.868 | 2.746 | Cullin (PF00888, IPR001373, SM00182): Cullin family EBP50_C (PF09007, IPR015098): EBP50, C-terminal Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain PG_binding_4 (PF12229, IPR022029): Putative peptidoglycan binding domain MDFI (PF15316, IPR026134): MyoD family inhibitor |
12 |
CUL5 | suppressor | 17 | 0.794 | 21.605 | Cullin (PF00888, IPR001373, SM00182): Cullin family GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
13 |
DCUN1D1 | interactor | 13 | 0.936 | 0.905 | Cullin_binding (PF03556, IPR005176): Cullin binding UBA_4 (PF14555): UBA-like domain |
14 |
DICER1 | suppressor | 6 | 0.500 | 57.934 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Dicer_dimer (PF03368, IPR005034): Dicer dimerisation domain PAZ (PF02170, IPR003100, SM00949): PAZ domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain Ribonuclease_3 (PF00636, IPR000999, SM00535): Ribonuclease III domain PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 (PF15387, IPR027893): Domain of unknown function (DUF4611) |
15 |
EDEM1 | interactor | 1 | 0 | 0 | Glyco_hydro_47 (PF01532, IPR001382): Glycosyl hydrolase family 47 |
16 |
ESRRB | suppressor | 2 | 1.000 | 0 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
17 |
FOXRED2 | interactor | 1 | 0 | 0 | Pyr_redox_3 (PF13738): Pyridine nucleotide-disulphide oxidoreductase |
18 |
FUS | suppressor | 16 | 0.842 | 4.034 | Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others Limkain-b1 (PF11608, IPR024582): Limkain b1 FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head |
19 |
GAN | protein found in more fusions | 4 | 1.000 | 0 | BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif Kelch_3 (PF13415): Galactose oxidase, central domain Kelch_5 (PF13854): Kelch motif |
20 |
HIST1H1A | interactor | 4 | 0.333 | 40.397 | Mucin (PF01456, IPR000458): Mucin-like glycoprotein Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal |
21 |
HNRNPA1 | interactor | 18 | 0.684 | 26.714 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1 |
22 |
HSPA4 | interactor | 10 | 0.911 | 0.671 | Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region HSP70 (PF00012, IPR013126): Hsp70 protein TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5 |
23 |
HSPA4L | interactor | 3 | 1.000 | 0 | HSP70 (PF00012, IPR013126): Hsp70 protein |
24 |
HSPA5 | oncoprotein | 23 | 0.506 | 116.534 | HSP70 (PF00012, IPR013126): Hsp70 protein |
25 |
IFI16 | suppressor | 4 | 0.333 | 14.736 | HIN (PF02760, IPR004021): HIN-200/IF120x domain PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain Mitofilin (PF09731, IPR019133): Mitochondrial inner membrane protein |
26 |
LIN28A | interactor | 1 | 0 | 0 | CSD (PF00313, IPR002059): 'Cold-shock' DNA-binding domain zf-CCHC (PF00098, IPR001878): Zinc knuckle zf-CCHC_6 (PF15288): Zinc knuckle |
27 |
LIN28B | interactor | 3 | 0.333 | 17.491 | CSD (PF00313, IPR002059): 'Cold-shock' DNA-binding domain zf-CCHC (PF00098, IPR001878): Zinc knuckle |
28 |
MAGEA11 | interactor | 2 | 0 | 0 | MAGE (PF01454, IPR002190): MAGE family MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal |
29 |
MCM2 | oncoprotein | 12 | 0.636 | 47.080 | AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
30 |
NEDD8 | interactor | 14 | 0.872 | 2.229 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
31 |
NTRK1 | oncoprotein | 19 | 0.575 | 95.230 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
32 |
PCSK9 | interactor | 1 | 0 | 0 | Peptidase_S8 (PF00082, IPR000209): Subtilase family Inhibitor_I9 (PF05922, IPR010259): Peptidase inhibitor I9 |
33 |
SFTPC | protein found in more fusions | 4 | 1.000 | 0 | BRICHOS (PF04089, IPR007084, SM01039): BRICHOS domain SP_C-Propep (PF08999, IPR015091): Surfactant protein C, N terminal propeptide |
34 |
SMURF2 | protein found in more fusions | 2 | 0 | 0 | C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) |
35 |
TCF3 | suppressor | 2 | 0 | 0 | CDC45 (PF02724, IPR003874): CDC45-like protein HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain DUF3682 (PF12446, IPR022152): Protein of unknown function (DUF3682) |
36 |
TCTN1 | interactor | 2 | 1.000 | 0 | DUF1619 (PF07773, IPR011677): Protein of unknown function (DUF1619) |
37 |
TCTN3 | interactor | 2 | 1.000 | 0 | DUF1619 (PF07773, IPR011677): Protein of unknown function (DUF1619) |
38 |
THAP2 | interactor | 1 | 0 | 0 | THAP (PF05485, IPR006612, SM00980): THAP domain |
39 |
TRAK2 | interactor | 1 | 0 | 0 | ZapB (PF06005, IPR009252): Cell division protein ZapB HAP1_N (PF04849, IPR006933): HAP1 N-terminal conserved region Milton (PF12448, IPR022154): Kinesin associated protein |
40 |
TXNL1 | interactor | 2 | 1.000 | 0 | PITH (PF06201, IPR010400): PITH domain Thioredoxin (PF00085, IPR013766): Thioredoxin |
41 |
VCP | protein found in more fusions | 15 | 0.725 | 15.891 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2 CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain TniB (PF05621, IPR008868): Bacterial TniB protein Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944) |