1 |
BCL11A | parental protein | 31 | 0.131 | 1578.719 | BSP_II (PF05432, IPR008412): Bone sialoprotein II (BSP-II) C1_4 (PF07975, IPR004595, SM01047): TFIIH C1-like domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-HIT (PF04438, IPR007529): HIT zinc finger zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain |
2 |
SRSF1 | parental protein | 156 | 0.198 | 7145.845 | Corona_nucleoca (PF00937, IPR001218): Coronavirus nucleocapsid protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
3 |
ACTC1 | interactor | 6 | 0.200 | 40.909 | Actin (PF00022, IPR004000, SM00268): Actin |
4 |
AHCYL1 | suppressor | 10 | 0.389 | 6.790 | AdoHcyase (PF05221, IPR000043, SM00996): S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD (PF00670, IPR015878, SM00997): S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF515 (PF04415, IPR007509): Protein of unknown function (DUF515) Big_3_5 (PF16640, IPR032109): Bacterial Ig-like domain (group 3) |
5 |
AIRE | interactor | 11 | 0.489 | 5.502 | PHD (PF00628, IPR019787, SM00249): PHD-finger SAND (PF01342, IPR000770, SM00258): SAND domain HSR (PF03172, IPR004865): HSR domain zf-PHD-like (PF15446): PHD/FYVE-zinc-finger like domain |
6 |
ALYREF | interactor | 42 | 0.474 | 79.156 | FYTT (PF07078, IPR009782): Forty-two-three protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
7 |
APP | protein found in more fusions | 45 | 0.237 | 737.392 | APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP) BUD22 (PF09073, IPR015158): BUD22 IncA (PF04156, IPR007285): IncA protein Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein |
8 |
BARD1 | suppressor | 36 | 0.338 | 128.754 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies) zf-RING_6 (PF14835): zf-RING of BARD1-type protein BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain |
9 |
BCL10 | suppressor | 5 | 0.833 | 0.447 | CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain |
10 |
BCL6 | oncoprotein | 9 | 0.357 | 43.932 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding DZR (PF12773, IPR025874): Double zinc ribbon zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2HE (PF16278, IPR032566): C2HE / C2H2 / C2HC zinc-binding finger |
11 |
BRCA1 | suppressor | 24 | 0.399 | 64.221 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT |
12 |
C1QBP | interactor | 27 | 0.342 | 66.880 | MAM33 (PF02330, IPR003428): Mitochondrial glycoprotein DUF3053 (PF11254, IPR021413): Protein of unknown function (DUF3053) |
13 |
CACNA1A | interactor | 2 | 0 | 5.873 | Ca_chan_IQ (PF08763, IPR014873, SM01062): Voltage gated calcium channel IQ domain GRP (PF07172, IPR010800): Glycine rich protein family Ion_trans (PF00520, IPR005821): Ion transport protein Roughex (PF06020, IPR009259): Drosophila roughex protein SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region GPHH (PF16905, IPR031649): Voltage-dependent L-type calcium channel, IQ-associated |
14 |
CAND1 | interactor | 72 | 0.413 | 288.965 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981) HEAT (PF02985, IPR000357): HEAT repeat TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20) RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II |
15 |
CDC5L | interactor | 67 | 0.415 | 336.574 | OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain |
16 |
CDCA3 | interactor | 4 | 0.167 | 17.712 | NA |
17 |
CDK4 | oncoprotein | 10 | 0.422 | 39.180 | Pkinase (PF00069, IPR000719): Protein kinase domain |
18 |
CDK6 | suppressor | 13 | 0.379 | 107.364 | Pkinase (PF00069, IPR000719): Protein kinase domain |
19 |
CHD4 | oncoprotein | 24 | 0.407 | 144.257 | CDC27 (PF09507, IPR019038): DNA polymerase subunit Cdc27 CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain CHDNT (PF08073, IPR012958): CHDNT (NUC034) domain Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain DTHCT (PF08070, IPR012542): DTHCT (NUC029) region DUF1086 (PF06461, IPR009462, SM01146): Domain of Unknown Function (DUF1086) DUF1087 (PF06465, IPR009463, SM01147): Domain of Unknown Function (DUF1087) PHD (PF00628, IPR019787, SM00249): PHD-finger Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain FAM176 (PF14851): FAM176 family Coilin_N (PF15862, IPR031722): Coilin N-terminus |
20 |
CIR1 | interactor | 4 | 1.000 | 0 | DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755) EVI2A (PF05399, IPR008608): Ectropic viral integration site 2A protein (EVI2A) Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 IncA (PF04156, IPR007285): IncA protein Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR YebO (PF13974, IPR025594): YebO-like protein CSRNP_N (PF16019, IPR031972): Cysteine/serine-rich nuclear protein N-terminus |
21 |
CLK1 | interactor | 18 | 0.537 | 7.745 | PDGF_N (PF04692, IPR006782): Platelet-derived growth factor, N terminal region Pkinase (PF00069, IPR000719): Protein kinase domain |
22 |
COPS5 | protein found in more fusions | 62 | 0.438 | 210.398 | JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease |
23 |
CUL1 | suppressor | 59 | 0.467 | 301.333 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
24 |
CUL2 | suppressor | 44 | 0.480 | 69.928 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
25 |
CUL3 | protein found in more fusions | 81 | 0.356 | 755.181 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal |
26 |
CUL4B | oncoprotein | 36 | 0.414 | 149.311 | Cullin (PF00888, IPR001373, SM00182): Cullin family EBP50_C (PF09007, IPR015098): EBP50, C-terminal Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain PG_binding_4 (PF12229, IPR022029): Putative peptidoglycan binding domain MDFI (PF15316, IPR026134): MyoD family inhibitor |
27 |
CUL7 | protein found in more fusions | 69 | 0.340 | 351.672 | ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7 |
28 |
CXCL1 | oncoprotein | 3 | 1.000 | 0 | IL8 (PF00048, IPR001811, SM00199): Small cytokines (intecrine/chemokine), interleukin-8 like |
29 |
DDX17 | protein found in more fusions | 49 | 0.434 | 170.649 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Ferritin (PF00210, IPR008331): Ferritin-like domain GRP (PF07172, IPR010800): Glycine rich protein family Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
30 |
DDX5 | oncoprotein | 63 | 0.414 | 315.322 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase P68HR (PF08061, IPR012587): P68HR (NUC004) repeat ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
31 |
DHX15 | interactor | 54 | 0.474 | 130.353 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain AAA_29 (PF13555): P-loop containing region of AAA domain |
32 |
DHX9 | oncoprotein | 56 | 0.436 | 170.286 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold T2SSE (PF00437, IPR001482): Type II/IV secretion system protein HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
33 |
DIDO1 | suppressor | 6 | 0.733 | 0.552 | PHD (PF00628, IPR019787, SM00249): PHD-finger SlyX (PF04102, IPR007236): SlyX SPOC (PF07744, IPR012921): SPOC domain TFIIS_M (PF07500, IPR003618): Transcription factor S-II (TFIIS), central domain MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 |
34 |
DYRK1A | oncoprotein | 13 | 0.424 | 9.147 | DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755) Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region Pkinase (PF00069, IPR000719): Protein kinase domain FAM199X (PF15814, IPR029672): Protein family FAM199X |
35 |
ECT2 | suppressor | 10 | 0.356 | 16.018 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain PTCB-BRCT (PF12738, IPR001357): twin BRCT domain PGBA_C (PF15437, IPR032737): Plasminogen-binding protein pgbA C-terminal |
36 |
EED | suppressor | 61 | 0.354 | 324.946 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
37 |
EFTUD2 | interactor | 46 | 0.482 | 100.660 | EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 EFG_II (PF14492, IPR009022): Elongation Factor G, domain II EFTUD2 (PF16004, IPR031950): 116 kDa U5 small nuclear ribonucleoprotein component N-terminus |
38 |
EIF4A3 | interactor | 62 | 0.464 | 259.589 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
39 |
ELAVL1 | oncoprotein | 71 | 0.252 | 1429.881 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
40 |
ESR1 | suppressor | 70 | 0.267 | 1060.633 | Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal |
41 |
EWSR1 | oncoprotein | 47 | 0.400 | 230.051 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head |
42 |
EZH2 | suppressor | 36 | 0.382 | 109.217 | CDC45 (PF02724, IPR003874): CDC45-like protein TCR (PF03638, IPR005172, SM01114): Tesmin/TSO1-like CXC domain, cysteine-rich domain SET (PF00856, IPR001214, SM00317): SET domain EZH2_WD-Binding (PF11616, IPR021654): WD repeat binding protein EZH2 Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal |
43 |
FBXO6 | interactor | 28 | 0.439 | 35.364 | FBA (PF04300, IPR007397): F-box associated region F-box-like (PF12937, IPR001810): F-box-like |
44 |
FN1 | oncoprotein | 42 | 0.366 | 126.294 | fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) |
45 |
GCN1 | interactor | 17 | 0.478 | 8.331 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat HEAT (PF02985, IPR000357): HEAT repeat CLASP_N (PF12348, IPR024395): CLASP N terminal MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal TFCD_C (PF12612, IPR022577): Tubulin folding cofactor D C terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II |
46 |
GMCL1P1 | interactor | 4 | 0.500 | 9.996 | NA |
47 |
GNAI2 | oncoprotein | 6 | 0.667 | 0.696 | G-alpha (PF00503, IPR001019, SM00275): G-protein alpha subunit |
48 |
GRK5 | protein found in more fusions | 17 | 0.392 | 44.646 | Pkinase (PF00069, IPR000719): Protein kinase domain RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain |
49 |
HABP4 | interactor | 7 | 0.381 | 13.087 | HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal |
50 |
HDAC1 | suppressor | 34 | 0.297 | 422.234 | FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain |
51 |
HDAC2 | suppressor | 38 | 0.342 | 390.742 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1 |
52 |
HDAC5 | protein found in more fusions | 38 | 0.369 | 232.398 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NOA36 (PF06524, IPR010531): NOA36 protein Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3 HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4 |
53 |
HDGF | interactor | 33 | 0.356 | 109.405 | PWWP (PF00855, IPR000313, SM00293): PWWP domain |
54 |
HIPK3 | interactor | 8 | 0.429 | 64.996 | Pkinase (PF00069, IPR000719): Protein kinase domain |
55 |
HNRNPA0 | interactor | 36 | 0.651 | 29.488 | SAP130_C (PF16014, IPR031963): Histone deacetylase complex subunit SAP130 C-terminus |
56 |
HNRNPA1 | interactor | 70 | 0.423 | 283.435 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1 |
57 |
HNRNPDL | interactor | 31 | 0.596 | 28.453 | CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
58 |
HNRNPF | interactor | 41 | 0.562 | 55.737 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spot_14 (PF07084, IPR009786): Thyroid hormone-inducible hepatic protein Spot 14 zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger |
59 |
HNRNPH3 | protein found in more fusions | 30 | 0.591 | 19.119 | Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
60 |
HNRNPK | oncoprotein | 61 | 0.443 | 389.722 | ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain KH_1 (PF00013, IPR004088, SM00322): KH domain |
61 |
HNRNPM | interactor | 63 | 0.390 | 386.781 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNP_M (PF11532, IPR024666): Heterogeneous nuclear ribonucleoprotein M Collagen_mid (PF15984, IPR031929): Bacterial collagen, middle region |
62 |
HNRNPR | interactor | 56 | 0.488 | 164.812 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1 |
63 |
HNRNPU | interactor | 69 | 0.379 | 313.875 | CDC45 (PF02724, IPR003874): CDC45-like protein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SAP (PF02037, IPR003034, SM00513): SAP domain SPRY (PF00622, IPR003877, SM00449): SPRY domain AAA_33 (PF13671): AAA domain WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
64 |
HUWE1 | oncoprotein | 36 | 0.368 | 99.868 | BUD22 (PF09073, IPR015158): BUD22 DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908) DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Mucin (PF01456, IPR000458): Mucin-like glycoprotein Nop14 (PF04147, IPR007276): Nop14-like family PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32 RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain WWE (PF02825, IPR004170, SM00678): WWE domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414) |
65 |
IGBP1 | interactor | 6 | 0.333 | 9.732 | TAP42 (PF04177, IPR007304): TAP42-like family |
66 |
IK | protein found in more fusions | 29 | 0.489 | 37.569 | Lsm_interact (PF05391, IPR008669): Lsm interaction motif RED_C (PF07807, IPR012492): RED-like protein C-terminal region RED_N (PF07808, IPR012916): RED-like protein N-terminal region PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term |
67 |
ILVBL | interactor | 4 | 0.667 | 1.072 | TPP_enzyme_C (PF02775, IPR011766): Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N (PF02776, IPR012001): Thiamine pyrophosphate enzyme, N-terminal TPP binding domain |
68 |
LMO1 | oncoprotein | 1 | 0 | 0 | LIM (PF00412, IPR001781, SM00132): LIM domain Vps39_2 (PF10367, IPR019453): Vacuolar sorting protein 39 domain 2 |
69 |
LNX1 | protein found in more fusions | 7 | 0.333 | 12.357 | PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) |
70 |
LOC255308 | interactor | 3 | 0.667 | 0.400 | NA |
71 |
LUC7L2 | protein found in more fusions | 46 | 0.392 | 159.504 | LUC7 (PF03194, IPR004882): LUC7 N_terminus Paramyxo_ncap (PF00973, IPR002021): Paramyxovirus nucleocapsid protein Methyltransf_32 (PF13679, IPR025714): Methyltransferase domain |
72 |
LUC7L3 | protein found in more fusions | 31 | 0.405 | 48.151 | LUC7 (PF03194, IPR004882): LUC7 N_terminus Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) DDRGK (PF09756, IPR019153, SM01128): DDRGK domain |
73 |
LUZP4 | interactor | 13 | 0.682 | 2.705 | Pox_Ag35 (PF03286, IPR004966): Pox virus Ag35 surface protein ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26 DUF2570 (PF10828, IPR022538): Protein of unknown function (DUF2570) |
74 |
MAGOH | interactor | 43 | 0.427 | 127.929 | Mago_nashi (PF02792, IPR004023): Mago nashi protein |
75 |
MBD3 | interactor | 17 | 0.442 | 92.979 | DUF2201_N (PF13203, IPR025154): Putative metallopeptidase domain |
76 |
MBD3L1 | interactor | 8 | 1.000 | 0 | MBD_C (PF14048, IPR025884): C-terminal domain of methyl-CpG binding protein 2 and 3 MBDa (PF16564, IPR032343): p55-binding region of Methyl-CpG-binding domain proteins MBD |
77 |
MDC1 | suppressor | 23 | 0.375 | 48.839 | FHA (PF00498, IPR000253, SM00240): FHA domain DUF3274 (PF11678, IPR021692): Protein of unknown function (DUF3274) Yop-YscD_cpl (PF16697, IPR032030): Inner membrane component of T3SS, cytoplasmic domain RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain |
78 |
MOV10 | interactor | 35 | 0.341 | 226.043 | AAA_12 (PF13087): AAA domain AAA_30 (PF13604): AAA domain |
79 |
MPG | interactor | 8 | 0.500 | 3.068 | Pur_DNA_glyco (PF02245, IPR003180): Methylpurine-DNA glycosylase (MPG) |
80 |
MTA1 | oncoprotein | 19 | 0.532 | 87.662 | BAH (PF01426, IPR001025, SM00439): BAH domain ELM2 (PF01448, IPR000949): ELM2 domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain GATA (PF00320, IPR000679, SM00401): GATA zinc finger |
81 |
MTA2 | interactor | 25 | 0.367 | 199.005 | BAH (PF01426, IPR001025, SM00439): BAH domain ELM2 (PF01448, IPR000949): ELM2 domain Resolvase (PF00239, IPR006119, SM00857): Resolvase, N terminal domain DDA1 (PF10172, IPR018276): Det1 complexing ubiquitin ligase Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain GATA (PF00320, IPR000679, SM00401): GATA zinc finger |
82 |
NCK2 | interactor | 7 | 0.200 | 29.343 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain |
83 |
NCSTN | interactor | 25 | 0.343 | 74.366 | Nicastrin (PF05450, IPR008710): Nicastrin Ost4 (PF10215, IPR018943): Oligosaccaryltransferase |
84 |
NPM1 | suppressor | 50 | 0.308 | 295.690 | Nucleoplasmin (PF03066): Nucleoplasmin/nucleophosmin domain SDA1 (PF05285, IPR007949): SDA1 NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain |
85 |
NR2E1 | interactor | 5 | 0.400 | 9.832 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
86 |
NR2E3 | interactor | 1 | 0 | 0 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
87 |
NR2F1 | oncoprotein | 4 | 0 | 20.303 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
88 |
NR2F2 | protein found in more fusions | 6 | 0.300 | 14.172 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
89 |
NR2F6 | oncoprotein | 4 | 0.167 | 22.406 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
90 |
NTRK1 | oncoprotein | 87 | 0.312 | 1070.742 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
91 |
NXF1 | interactor | 45 | 0.407 | 178.220 | NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain LRR_8 (PF13855, IPR001611): Leucine rich repeat |
92 |
OBSL1 | interactor | 73 | 0.324 | 391.216 | BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain |
93 |
PAN2 | interactor | 20 | 0.463 | 48.641 | RNase_T (PF00929, IPR013520): Exonuclease UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase WD40_like (PF17005, IPR031544): WD40-like domain |
94 |
PARK2 | suppressor | 30 | 0.382 | 59.693 | IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
95 |
PAXIP1 | interactor | 25 | 0.360 | 58.645 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain IPT (PF01745, IPR002648, SM00429): Isopentenyl transferase SURF6 (PF04935, IPR007019): Surfeit locus protein 6 DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance PTCB-BRCT (PF12738, IPR001357): twin BRCT domain BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT (PF16759, IPR031916): DNA ligase 3 BRCT domain RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain |
96 |
PHF20L1 | interactor | 9 | 0.639 | 8.891 | MBT (PF02820, IPR004092, SM00561): mbt repeat PHD (PF00628, IPR019787, SM00249): PHD-finger U79_P34 (PF03064, IPR004138): HSV U79 / HCMV P34 DUF3776 (PF12618, IPR022255): Protein of unknown function (DUF3776) CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal DUF4537 (PF15057, IPR032770): Domain of unknown function (DUF4537) PEHE (PF15275, IPR029332): PEHE domain EFTUD2 (PF16004, IPR031950): 116 kDa U5 small nuclear ribonucleoprotein component N-terminus PHD20L1_u1 (PF16660): PHD finger protein 20-like protein 1 |
97 |
PHGDH | interactor | 37 | 0.339 | 120.789 | 2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain |
98 |
PIAS1 | suppressor | 13 | 0.485 | 15.270 | Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger PINIT (PF14324, IPR023321): PINIT domain UPF0544 (PF15749, IPR032739): Uncharacterised protein family UPF0544 |
99 |
PIAS3 | oncoprotein | 7 | 0.381 | 27.013 | SAP (PF02037, IPR003034, SM00513): SAP domain zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger PINIT (PF14324, IPR023321): PINIT domain |
100 |
PRPF19 | protein found in more fusions | 51 | 0.509 | 96.035 | Prp19 (PF08606, IPR013915): Prp19/Pso4-like WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat U-box (PF04564, IPR003613, SM00504): U-box domain ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
101 |
PRPF4 | interactor | 26 | 0.647 | 15.012 | PRP4 (PF08799, IPR014906): pre-mRNA processing factor 4 (PRP4) like WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain WD40_like (PF17005, IPR031544): WD40-like domain |
102 |
PRPF4B | oncoprotein | 18 | 0.503 | 14.008 | Afi1 (PF07792, IPR012860): Docking domain of Afi1 for Arf3 in vesicle trafficking Ureide_permease (PF07168, IPR009834): Ureide permease Pkinase (PF00069, IPR000719): Protein kinase domain Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal |
103 |
PSIP1 | oncoprotein | 13 | 0.474 | 8.569 | AT_hook (PF02178, IPR017956, SM00384): AT hook motif BEX (PF04538, IPR021156): Brain expressed X-linked like family DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510) PGA2 (PF07543, IPR011431): Protein trafficking PGA2 PWWP (PF00855, IPR000313, SM00293): PWWP domain LEDGF (PF11467, IPR021567): Lens epithelium-derived growth factor (LEDGF) TERB2 (PF15101, IPR028065): Telomere-associated protein TERB2 |
104 |
RBBP7 | suppressor | 21 | 0.429 | 114.588 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex |
105 |
RBM14 | suppressor | 37 | 0.455 | 62.592 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1 |
106 |
RBM39 | oncoprotein | 53 | 0.403 | 171.839 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 RBM39linker (PF15519, IPR029123): linker between RRM2 and RRM3 domains in RBM39 protein |
107 |
RNF2 | interactor | 58 | 0.331 | 293.153 | zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like |
108 |
RNPS1 | interactor | 47 | 0.479 | 96.430 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457) Macoilin (PF09726, IPR019130): Transmembrane protein |
109 |
RRP1B | interactor | 22 | 0.506 | 25.931 | Nop52 (PF05997, IPR010301): Nucleolar protein,Nop52 |
110 |
SAP18 | interactor | 32 | 0.389 | 108.854 | SAP18 (PF06487, IPR010516): Sin3 associated polypeptide p18 (SAP18) |
111 |
SART1 | interactor | 47 | 0.434 | 152.954 | SART-1 (PF03343, IPR005011): SART-1 family Dsh_C (PF12316, IPR024580): Segment polarity protein dishevelled (Dsh) C terminal |
112 |
SCAF11 | interactor | 5 | 0.800 | 0.217 | DUF566 (PF04484, IPR007573): Family of unknown function (DUF566) Phage_XkdX (PF09693, IPR010022): Phage uncharacterised protein (Phage_XkdX) zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) |
113 |
SF3A1 | interactor | 50 | 0.457 | 169.608 | TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit Surp (PF01805, IPR000061, SM00648): Surp module ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family PRP21_like_P (PF12230, IPR022030): Pre-mRNA splicing factor PRP21 like protein |
114 |
SF3A2 | interactor | 40 | 0.554 | 44.018 | Cytadhesin_P30 (PF07271, IPR009896): Cytadhesin P30/P32 PRP4 (PF08799, IPR014906): pre-mRNA processing factor 4 (PRP4) like Totivirus_coat (PF05518, IPR008871): Totivirus coat protein zf-met (PF12874): Zinc-finger of C2H2 type ARL6IP6 (PF15062, IPR029383): Haemopoietic lineage transmembrane helix SF3A2 (PF16835, IPR031781): Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) |
115 |
SF3B1 | oncoprotein | 52 | 0.473 | 143.637 | Dopey_N (PF04118, IPR007249): Dopey, N-terminal HEAT (PF02985, IPR000357): HEAT repeat SF3b1 (PF08920, IPR015016): Splicing factor 3B subunit 1 UNC45-central (PF11701, IPR024660): Myosin-binding striated muscle assembly central Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats |
116 |
SF3B3 | interactor | 51 | 0.493 | 108.535 | CPSF_A (PF03178, IPR004871): CPSF A subunit region MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term |
117 |
SFN | suppressor | 21 | 0.374 | 39.440 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
118 |
SHMT2 | interactor | 19 | 0.456 | 19.167 | SHMT (PF00464, IPR001085): Serine hydroxymethyltransferase |
119 |
SIRT1 | suppressor | 18 | 0.419 | 72.827 | DUF592 (PF04574, IPR007654): Protein of unknown function (DUF592) SIR2 (PF02146, IPR003000): Sir2 family TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain |
120 |
SLC30A1 | interactor | 2 | 1.000 | 0 | Cation_efflux (PF01545, IPR002524): Cation efflux family ZT_dimer (PF16916, IPR027470): Dimerisation domain of Zinc Transporter |
121 |
SLC30A5 | oncoprotein | 2 | 1.000 | 0 | Cation_efflux (PF01545, IPR002524): Cation efflux family DUF4199 (PF13858, IPR025250): Protein of unknown function (DUF4199) |
122 |
SMARCAD1 | interactor | 20 | 0.537 | 138.704 | CUE (PF02845, IPR003892, SM00546): CUE domain Pox_D5 (PF03288, IPR004968): Poxvirus D5 protein-like SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
123 |
SMU1 | interactor | 20 | 0.521 | 13.221 | LisH (PF08513, IPR013720, SM00667): LisH WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
124 |
SMURF1 | interactor | 24 | 0.395 | 119.324 | C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) |
125 |
SNAP23 | interactor | 5 | 0.833 | 0.143 | DivIC (PF04977, IPR007060): Septum formation initiator DUF16 (PF01519, IPR002862): Protein of unknown function DUF16 SNAP-25 (PF00835, IPR000928): SNAP-25 family DUF5089 (PF17002, IPR031547): Domain of unknown function (DUF5089) |
126 |
SNIP1 | interactor | 14 | 0.593 | 7.225 | FHA (PF00498, IPR000253, SM00240): FHA domain MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 FAM176 (PF14851): FAM176 family |
127 |
SNRNP200 | protein found in more fusions | 49 | 0.480 | 113.861 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase DUF603 (PF04645, IPR006739): Protein of unknown function, DUF603 Sec63 (PF02889, IPR004179, SM00973): Sec63 Brl domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
128 |
SNRNP70 | interactor | 46 | 0.468 | 89.759 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal |
129 |
SNRPA1 | interactor | 36 | 0.546 | 57.406 | LRR_9 (PF14580): Leucine-rich repeat |
130 |
SNW1 | protein found in more fusions | 66 | 0.409 | 403.165 | SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term SIR4_SID (PF16991, IPR031556): Sir4 SID domain |
131 |
SPRTN | interactor | 12 | 0.470 | 6.302 | GreA_GreB (PF01272, IPR001437): Transcription elongation factor, GreA/GreB, C-term SprT-like (PF10263, IPR006640, SM00731): SprT-like family PRP21_like_P (PF12230, IPR022030): Pre-mRNA splicing factor PRP21 like protein |
132 |
SREK1 | protein found in more fusions | 30 | 0.478 | 28.632 | Ureide_permease (PF07168, IPR009834): Ureide permease RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RP-C_C (PF11800, IPR021760): Replication protein C C-terminal region PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) BRD4_CDT (PF17105, IPR031354): C-terminal domain of bromodomain protein 4 |
133 |
SRPK1 | interactor | 42 | 0.456 | 159.446 | FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid) Pkinase (PF00069, IPR000719): Protein kinase domain NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1 |
134 |
SRPK2 | oncoprotein | 46 | 0.422 | 215.816 | DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387) Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator Pkinase (PF00069, IPR000719): Protein kinase domain S-antigen (PF05756, IPR008825): S-antigen protein DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) |
135 |
SRPK3 | interactor | 18 | 0.464 | 10.892 | Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein Pkinase (PF00069, IPR000719): Protein kinase domain |
136 |
SRRM2 | interactor | 62 | 0.390 | 353.872 | cwf21 (PF08312, IPR013170, SM01115): cwf21 domain DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Pap_E4 (PF02711, IPR003861): E4 protein RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 CTD (PF12815, IPR024945, SM01104): Spt5 C-terminal nonapeptide repeat binding Spt4 DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614) |
137 |
SRSF10 | interactor | 38 | 0.309 | 135.828 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term |
138 |
SRSF11 | interactor | 38 | 0.435 | 92.664 | Rtf2 (PF04641, IPR027799): Rtf2 RING-finger RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TP2 (PF01254, IPR000678): Nuclear transition protein 2 Transformer (PF06495, IPR010519): Fruit fly transformer protein FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
139 |
SRSF2 | oncoprotein | 44 | 0.398 | 139.435 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TP2 (PF01254, IPR000678): Nuclear transition protein 2 Transformer (PF06495, IPR010519): Fruit fly transformer protein Apt1 (PF10351, IPR019443): Golgi-body localisation protein domain DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457) |
140 |
SRSF3 | oncoprotein | 58 | 0.357 | 285.655 | DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
141 |
SRSF4 | interactor | 28 | 0.444 | 45.210 | Corona_nucleoca (PF00937, IPR001218): Coronavirus nucleocapsid protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term |
142 |
SRSF5 | interactor | 49 | 0.366 | 218.945 | DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term |
143 |
SRSF6 | oncoprotein | 43 | 0.426 | 115.202 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Tox-HNH-EHHH (PF15657, IPR028048): HNH/Endo VII superfamily nuclease toxins |
144 |
SRSF7 | interactor | 62 | 0.388 | 281.189 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TP2 (PF01254, IPR000678): Nuclear transition protein 2 zf-CCHC (PF00098, IPR001878): Zinc knuckle |
145 |
SRSF9 | interactor | 37 | 0.450 | 92.103 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
146 |
SSR1 | interactor | 12 | 0.424 | 7.978 | TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit |
147 |
STAU1 | protein found in more fusions | 44 | 0.468 | 94.682 | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Staufen_C (PF16482, IPR032478): Staufen C-terminal domain |
148 |
SUB1 | interactor | 17 | 0.292 | 28.066 | Dehydrin (PF00257, IPR000167): Dehydrin PC4 (PF02229, IPR003173): Transcriptional Coactivator p15 (PC4) |
149 |
SUMO1 | interactor | 15 | 0.352 | 68.588 | Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like |
150 |
SURF4 | interactor | 11 | 0.491 | 4.851 | SURF4 (PF02077, IPR002995): SURF4 family |
151 |
SUZ12 | suppressor | 51 | 0.378 | 211.623 | DUF2070 (PF09843, IPR019204): Predicted membrane protein (DUF2070) VEFS-Box (PF09733, IPR019135): VEFS-Box of polycomb protein |
152 |
SYNCRIP | interactor | 44 | 0.485 | 152.126 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1 |
153 |
TADA2A | interactor | 23 | 0.435 | 54.056 | SWIRM (PF04433, IPR007526): SWIRM domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain |
154 |
TCERG1 | interactor | 20 | 0.521 | 14.114 | FF (PF01846, IPR002713, SM00441): FF domain WW (PF00397, IPR001202, SM00456): WW domain Folliculin (PF11704, IPR021713): Vesicle coat protein involved in Golgi to plasma membrane transport DUF3807 (PF12720, IPR024526): Protein of unknown function (DUF3807) DUF3886 (PF13025, IPR024980): Protein of unknown function (DUF3886) Spore_coat_CotO (PF14153, IPR025439): Spore coat protein CotO FAM150 (PF15129, IPR029364): FAM150 family |
155 |
TMEM43 | interactor | 3 | 1.000 | 0 | TMEM43 (PF07787, IPR012430): Transmembrane protein 43 UPF0697 (PF15117, IPR029368): Uncharacterised protein family UPF0697 |
156 |
TOMM20 | interactor | 5 | 0.500 | 1.653 | RSN1_7TM (PF02714, IPR003864): Calcium-dependent channel, 7TM region, putative phosphate MAS20 (PF02064, IPR002056): MAS20 protein import receptor |
157 |
TOP1 | oncoprotein | 41 | 0.535 | 58.331 | DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) Topoisom_I (PF01028, IPR013500): Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N (PF02919, IPR008336): Eukaryotic DNA topoisomerase I, DNA binding fragment MCM_bind (PF09739, IPR019140): Mini-chromosome maintenance replisome factor Sox_N (PF12444, IPR022151): Sox developmental protein N terminal Topo_C_assoc (PF14370, IPR025834): C-terminal topoisomerase domain DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614) TonB_N (PF16031): TonB N-terminal region |
158 |
TP53 | suppressor | 54 | 0.279 | 479.967 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif |
159 |
TP53BP1 | suppressor | 14 | 0.374 | 18.092 | 53-BP1_Tudor (PF09038, IPR015125): Tumour suppressor p53-binding protein-1 Tudor BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal DUF4772 (PF15997, IPR031940): Domain of unknown function (DUF4772) BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain |
160 |
TRA2B | interactor | 42 | 0.460 | 120.289 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein |
161 |
TRAF2 | interactor | 15 | 0.330 | 63.124 | MATH (PF00917, IPR002083, SM00061): MATH domain Sina (PF03145, IPR018121): Seven in absentia protein family SlyX (PF04102, IPR007236): SlyX zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain zf-C3HC4_5 (PF17121, IPR001841): Zinc finger, C3HC4 type (RING finger) |
162 |
TRAF3IP2 | interactor | 6 | 0.800 | 1.106 | SEFIR (PF08357, IPR013568): SEFIR domain Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) |
163 |
TRAF5 | interactor | 7 | 0.733 | 2.242 | Sina (PF03145, IPR018121): Seven in absentia protein family zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain HMMR_N (PF15905, IPR031787): Hyaluronan mediated motility receptor N-terminal Spc29 (PF17082, IPR031392): Spindle Pole Component 29 |
164 |
TRIM55 | interactor | 17 | 0.417 | 42.857 | Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein NABP (PF07990, IPR012940): Nucleic acid binding protein NABP zf-HIT (PF04438, IPR007529): HIT zinc finger zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger |
165 |
TRMT112 | interactor | 17 | 0.463 | 9.033 | Trm112p (PF03966, IPR005651): Trm112p-like protein |
166 |
U2AF1 | oncoprotein | 49 | 0.451 | 162.299 | DUF1509 (PF07420, IPR010883): Protein of unknown function (DUF1509) KMP11 (PF03037, IPR004132): Kinetoplastid membrane protein 11 RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar) |
167 |
U2AF2 | protein found in more fusions | 74 | 0.452 | 290.901 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein |
168 |
UBC | protein found in more fusions | 47 | 0.360 | 373.002 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
169 |
UBE2I | interactor | 38 | 0.264 | 489.534 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
170 |
UBR5 | protein found in more fusions | 11 | 0.378 | 11.473 | CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain SDA1 (PF05285, IPR007949): SDA1 HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain E3_UbLigase_EDD (PF11547, IPR024725): E3 ubiquitin ligase EDD PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein |
171 |
UBXN4 | interactor | 2 | 0 | 5.545 | Asp-B-Hydro_N (PF05279, IPR007943): Aspartyl beta-hydroxylase N-terminal region Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like UBX (PF00789, IPR001012, SM00166): UBX domain Thioredoxin_7 (PF13899): Thioredoxin-like |
172 |
UTP14A | interactor | 23 | 0.411 | 25.540 | Utp14 (PF04615, IPR006709): Utp14 protein |
173 |
VASN | interactor | 9 | 0.528 | 1.794 | EGF (PF00008, IPR000742, SM00181): EGF-like domain EGF_2 (PF07974, IPR013111): EGF-like domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain TraW_N (PF12477, IPR025864): Sex factor F TraW protein N terminal LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat |
174 |
VTN | interactor | 26 | 0.505 | 24.187 | Hemopexin (PF00045, IPR018487, SM00120): Hemopexin Somatomedin_B (PF01033, IPR001212, SM00201): Somatomedin B domain |
175 |
WDR18 | interactor | 21 | 0.429 | 29.387 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 WD40_alt (PF14077, IPR026987): Alternative WD40 repeat motif |
176 |
XBP1 | protein found in more fusions | 5 | 0.667 | 0.425 | DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper DUF2630 (PF10944, IPR020311): Protein of unknown function (DUF2630) |
177 |
XPO1 | interactor | 43 | 0.274 | 273.156 | CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region |
178 |
YME1L1 | interactor | 2 | 0 | 4.754 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) Peptidase_M41 (PF01434, IPR000642): Peptidase family M41 |
179 |
YWHAE | oncoprotein | 28 | 0.489 | 31.784 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
180 |
YWHAQ | interactor | 28 | 0.484 | 36.618 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
181 |
ZBTB1 | interactor | 10 | 0.400 | 5.934 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-BED (PF02892, IPR003656, SM00614): BED zinc finger zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies) zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger |
182 |
ZBTB24 | interactor | 1 | 0 | 0 | AT_hook (PF02178, IPR017956, SM00384): AT hook motif BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zinc_ribbon_4 (PF13717): zinc-ribbon domain |
183 |
ZMYND11 | suppressor | 17 | 0.325 | 44.726 | DUF1002 (PF06207, IPR009343): Protein of unknown function (DUF1002) DUF1353 (PF07087, IPR010767): Protein of unknown function (DUF1353) PWWP (PF00855, IPR000313, SM00293): PWWP domain zf-MYND (PF01753, IPR002893): MYND finger zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box) Bromodomain (PF00439, IPR001487, SM00297): Bromodomain |
184 |
ZNF326 | interactor | 15 | 0.571 | 19.677 | AKAP95 (PF04988, IPR007071): A-kinase anchoring protein 95 (AKAP95) DUF678 (PF05077, IPR007769): Protein of unknown function (DUF678) PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated |