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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)99
The number (and %) of the onco-proteins14 (14.14 %)
The number (and %) of the tumor suppressors7 (7.07 %)
Total number of binary PPIs (saturation %)617 (12.72 %)
The number (and %) of affected PPIs97 (15.72 %)
The number of possible different fusions12
PPI diameter5
PPI radius3
The average degree of PPI11.838
Assortativity coefficient-0.1800
The network average Clustering coefficient0.527
The number (and %) of a zero Clustering coefficients19 (19.19 %)
The number (and %) of a zero Betweenness Centrality29 (29.29 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: POLR2F,PITX1 All fusions
Proteins found in more fusions EWSR1/MED15 (see 3 fusions); POLR2F/PIH1D1 (see 1 fusions); APP (see 5 fusions); MAGED1 (see 1 fusions); DVL3 (see 1 fusions); RBPMS (see 1 fusions); EWSR1 (see 1 fusions); POLR2E (see 1 fusions); POLR2A (see 2 fusions); SDC2 (see 2 fusions); SMAD3 (see 3 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 POLR2Fparental protein700.1763495.444RNA_pol_Rpb6 (PF01192, IPR006110): RNA polymerase Rpb6
2 PITX1parental protein270.0632003.509Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
OAR (PF03826, IPR003654): OAR domain
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
3 ALG13interactor100Glyco_tran_28_C (PF04101, IPR007235): Glycosyltransferase family 28 C-terminal domain
OTU (PF02338, IPR003323): OTU-like cysteine protease
SMN (PF06003, IPR010304): Survival motor neuron protein (SMN)
4 APPprotein found in more fusions110.244234.617APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
5 BAG5interactor100BAG (PF02179, IPR003103, SM00264): BAG domain
PDGF_N (PF04692, IPR006782): Platelet-derived growth factor, N terminal region
RRF (PF01765, IPR023584): Ribosome recycling factor
6 BDP1interactor21.0000SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein
DUF2917 (PF11142, IPR021317): Protein of unknown function (DUF2917)
UPF0542 (PF15086, IPR027877): Uncharacterised protein family UPF0542
Myb_DNA-bind_7 (PF15963): Myb DNA-binding like
7 C1orf94interactor50.8330.667DUF4688 (PF15752, IPR031496): Domain of unknown function (DUF4688)
8 CD3EAPinteractor80.7148.025Pol_alpha_B_N (PF08418, IPR013627): DNA polymerase alpha subunit B N-terminal
RNA_polI_A34 (PF08208, IPR013240): DNA-directed RNA polymerase I subunit RPA34.5
9 CDX4interactor100Caudal_act (PF04731, IPR006820): Caudal like protein activation region
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
10 CRCPinteractor120.9240.937RNA_pol_Rpb4 (PF03874, IPR005574): RNA polymerase Rpb4
Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein
11 CTDP1interactor140.64816.256Biotin_lipoyl (PF00364, IPR000089): Biotin-requiring enzyme
FCP1_C (PF09309, IPR015388): FCP1, C-terminal
NIF (PF03031, IPR004274): NLI interacting factor-like phosphatase
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
Apt1 (PF10351, IPR019443): Golgi-body localisation protein domain
TFIIE-A_C (PF11521, IPR021600): C-terminal general transcription factor TFIIE alpha
CAF1A (PF12253, IPR022043): Chromatin assembly factor 1 subunit A
PTCB-BRCT (PF12738, IPR001357): twin BRCT domain
HlyD_D23 (PF16576, IPR032317): Barrel-sandwich domain of CusB or HlyD membrane-fusion
12 DCAF4interactor100WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
DUF4221 (PF13970, IPR025316): Domain of unknown function (DUF4221)
13 DNTTIP1interactor4018.836DUF4385 (PF14328, IPR025494): Domain of unknown function (DUF4385)
14 DVL3protein found in more fusions31.0000DEP (PF00610, IPR000591, SM00049): Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)
Dishevelled (PF02377, IPR003351): Dishevelled specific domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
DIX (PF00778, IPR001158, SM00021): DIX domain
Dsh_C (PF12316, IPR024580): Segment polarity protein dishevelled (Dsh) C terminal
15 DYNC2LI1interactor100DLIC (PF05783, IPR022780): Dynein light intermediate chain (DLIC)
16 EGR1suppressor100zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
DUF3432 (PF11914, IPR021839): Domain of unknown function (DUF3432)
DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446)
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
17 ESR1suppressor230.476350.642Oest_recep (PF02159, IPR001292): Oestrogen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
18 EWSR1oncoprotein140.167456.387RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
19 GCOM1interactor100BRE1 (PF08647, IPR013956): BRE1 E3 ubiquitin ligase
DUF148 (PF02520, IPR003677): Domain of unknown function DUF148
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
GPHR_N (PF12537, IPR022535): The Golgi pH Regulator (GPHR) Family N-terminal
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
GCOM2 (PF15328, IPR026213): Putative GRINL1B complex locus protein 2
Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease
20 GPN1interactor140.70324.322ATP_bind_1 (PF03029, IPR004130): Conserved hypothetical ATP binding protein
NB-ARC (PF00931, IPR002182): NB-ARC domain
21 GPN3interactor230.474123.172ATP_bind_1 (PF03029, IPR004130): Conserved hypothetical ATP binding protein
22 GTF2Binteractor130.667200.479Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
TFIIB (PF00382, IPR013150): Transcription factor TFIIB repeat
TF_Zn_Ribbon (PF08271, IPR013137): TFIIB zinc-binding
23 GTF2F1interactor100.88914.411TFIIF_alpha (PF05793, IPR008851): Transcription initiation factor IIF, alpha subunit (TFIIF-alpha)
24 GTF2F2interactor160.64258.347TFIIF_beta (PF02270, IPR003196): Transcription initiation factor IIF, beta subunit
25 GTF3C1interactor30.6670.400B-block_TFIIIC (PF04182, IPR007309): B-block binding subunit of TFIIIC
26 HGSinteractor30.66723.613FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
VHS (PF00790, IPR002014, SM00288): VHS domain
EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
Hrs_helical (PF12210, IPR024641): Hepatocyte growth factor-regulated tyrosine kinase substrate
PIEZO (PF15917, IPR031805): Piezo
27 IL15RAinteractor100NA
28 IPO13interactor100IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
29 KDM3Asuppressor100C1_2 (PF03107, IPR004146): C1 domain
JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase
30 KEAP1oncoprotein40.33312.738BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
31 LZTS2suppressor50.40098.156CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
DUF1127 (PF06568, IPR009506): Domain of unknown function (DUF1127)
Fez1 (PF06818): Fez1
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
DUF4250 (PF14056, IPR025346): Domain of unknown function (DUF4250)
32 MAGED1protein found in more fusions50.8331.786MAGE (PF01454, IPR002190): MAGE family
33 MAP3K4suppressor200CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Pkinase (PF00069, IPR000719): Protein kinase domain
PLU-1 (PF08429, IPR013637): PLU-1-like protein
Radial_spoke_3 (PF06098, IPR009290): Radial spoke protein 3
DUF3682 (PF12446, IPR022152): Protein of unknown function (DUF3682)
DUF3958 (PF13125, IPR025014): Protein of unknown function (DUF3958)
34 MAST3interactor100DUF1908 (PF08926, IPR015022): Domain of unknown function (DUF1908)
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Pkinase (PF00069, IPR000719): Protein kinase domain
ACTL7A_N (PF16840, IPR031769): Actin-like protein 7A N-terminus
35 MED1interactor160.676149.988Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
Med1 (PF10744, IPR019680): Mediator of RNA polymerase II transcription subunit 1
DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614)
PNISR (PF15996, IPR031937): Arginine/serine-rich protein PNISR
36 MED10interactor190.75412.168Med10 (PF09748, IPR019145): Transcription factor subunit Med10 of Mediator complex
37 MED15protein found in more fusions130.538147.585Med15 (PF09606, IPR019087): ARC105 or Med15 subunit of Mediator complex non-fungal
38 MED19interactor210.66828.535Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19
39 MED25interactor110.8002.360Med25 (PF11232, IPR021394): Mediator complex subunit 25 PTOV activation and synapsin 2
Med25_SD1 (PF11235, IPR021397): Mediator complex subunit 25 synapsin 1
Med25_NR-box (PF11244, IPR021406): Mediator complex subunit 25 C-terminal NR box-containing
Med25_VWA (PF11265, IPR021419): Mediator complex subunit 25 von Willebrand factor type A
40 MED26interactor210.65260.412Med26 (PF08711, IPR017923): TFIIS helical bundle-like domain
Med26_C (PF15693, IPR031416): Mediator complex subunit 26 C-terminal
Med26_M (PF15694, IPR031417): Mediator complex subunit 26 middle domain
41 MED29interactor190.73911.828Med29 (PF11568, IPR021018): Mediator complex subunit 29
42 MED30interactor110.8674.651Med30 (PF11315, IPR021019): Mediator complex subunit 30
43 MED9interactor170.72117.052Med9 (PF07544, IPR011425): RNA polymerase II transcription mediator complex subunit 9
44 MGAT5Binteractor30.6671.244Glyco_transf_18 (PF15024): Glycosyltransferase family 18
45 NR5A1interactor30.33395.419zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
PRIMA1 (PF16101): Proline-rich membrane anchor 1
46 PIH1D1protein found in more fusions190.561382.084PIH1 (PF08190, IPR012981): pre-RNA processing PIH1/Nop17
47 PLEKHM2interactor100PH (PF00169, IPR001849, SM00233): PH domain
RUN (PF02759, IPR004012, SM00593): RUN domain
48 PLSCR1interactor60.200157.575Scramblase (PF03803, IPR005552): Scramblase
49 POLR1Ainteractor170.54435.618RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1
RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2
RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3
RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4
RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5
50 POLR1Binteractor120.7425.372RNA_pol_Rpa2_4 (PF06883, IPR009674): RNA polymerase I, Rpa2 specific domain
RNA_pol_Rpb2_1 (PF04563, IPR007644): RNA polymerase beta subunit
RNA_pol_Rpb2_3 (PF04565, IPR007645): RNA polymerase Rpb2, domain 3
RNA_pol_Rpb2_6 (PF00562, IPR007120): RNA polymerase Rpb2, domain 6
RNA_pol_Rpb2_7 (PF04560, IPR007641): RNA polymerase Rpb2, domain 7
51 POLR1Cinteractor250.437329.581RNA_pol_A_bac (PF01000, IPR011262): RNA polymerase Rpb3/RpoA insert domain
52 POLR1Dinteractor160.70812.234RNA_pol_L_2 (PF13656): RNA polymerase Rpb3/Rpb11 dimerisation domain
53 POLR1Einteractor51.0000RNA_pol_I_A49 (PF06870, IPR009668): A49-like RNA polymerase I associated factor
54 POLR2Aprotein found in more fusions400.391402.053RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1
RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2
RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3
RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4
RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5
RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat
55 POLR2Binteractor320.470140.598RNA_pol_Rpb2_1 (PF04563, IPR007644): RNA polymerase beta subunit
RNA_pol_Rpb2_3 (PF04565, IPR007645): RNA polymerase Rpb2, domain 3
RNA_pol_Rpb2_4 (PF04566, IPR007646): RNA polymerase Rpb2, domain 4
RNA_pol_Rpb2_5 (PF04567, IPR007647): RNA polymerase Rpb2, domain 5
RNA_pol_Rpb2_6 (PF00562, IPR007120): RNA polymerase Rpb2, domain 6
RNA_pol_Rpb2_7 (PF04560, IPR007641): RNA polymerase Rpb2, domain 7
56 POLR2Cinteractor340.466165.848RNA_pol_A_bac (PF01000, IPR011262): RNA polymerase Rpb3/RpoA insert domain
57 POLR2Eprotein found in more fusions410.387367.641RNA_pol_Rpb5_C (PF01191, IPR000783): RNA polymerase Rpb5, C-terminal domain
RNA_pol_Rpb5_N (PF03871, IPR005571): RNA polymerase Rpb5, N-terminal domain
58 POLR2Ginteractor360.455201.697SHS2_Rpb7-N (PF03876, IPR005576): SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397
S1 (PF00575, IPR003029, SM00316): S1 RNA binding domain
59 POLR2Hinteractor340.445158.272RNA_pol_Rpb8 (PF03870, IPR005570, SM00658): RNA polymerase Rpb8
60 POLR2Iinteractor240.58073.335RNA_POL_M_15KD (PF02150, IPR001529): RNA polymerases M/15 Kd subunit
TFIIS_C (PF01096, IPR001222): Transcription factor S-II (TFIIS)
CpXC (PF14353, IPR025682): CpXC protein
61 POLR2Jinteractor280.52165.557RNA_pol_L_2 (PF13656): RNA polymerase Rpb3/Rpb11 dimerisation domain
62 POLR2Kinteractor220.61970.917DNA_RNApol_7kD (PF03604, IPR006591, SM00659): DNA directed RNA polymerase, 7 kDa subunit
63 POLR2Minteractor150.80018.993GCOM2 (PF15328, IPR026213): Putative GRINL1B complex locus protein 2
64 POLR3Ainteractor240.533126.471RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1
RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2
RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3
RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4
RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5
65 POLR3Binteractor210.63326.616RNA_pol_Rpb2_1 (PF04563, IPR007644): RNA polymerase beta subunit
RNA_pol_Rpb2_3 (PF04565, IPR007645): RNA polymerase Rpb2, domain 3
RNA_pol_Rpb2_4 (PF04566, IPR007646): RNA polymerase Rpb2, domain 4
RNA_pol_Rpb2_5 (PF04567, IPR007647): RNA polymerase Rpb2, domain 5
RNA_pol_Rpb2_6 (PF00562, IPR007120): RNA polymerase Rpb2, domain 6
RNA_pol_Rpb2_7 (PF04560, IPR007641): RNA polymerase Rpb2, domain 7
66 POLR3Cinteractor170.65457.245HTH_9 (PF08221, IPR013197): RNA polymerase III subunit RPC82 helix-turn-helix domain
NIT (PF08376, IPR013587): Nitrate and nitrite sensing
RNA_pol_Rpc82 (PF05645, IPR008806): RNA polymerase III subunit RPC82
HD_4 (PF13328, IPR003607): HD domain
67 POLR3Dinteractor180.641263.695Atrophin-1 (PF03154, IPR002951): Atrophin-1 family
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
68 POLR3Einteractor210.49098.858Sin_N (PF04801, IPR006886): Sin-like protein conserved region
DUF2382 (PF09557, IPR019060): Domain of unknown function (DUF2382)
69 POLR3Finteractor140.8025.219RNA_pol_Rpc34 (PF05158, IPR007832): RNA polymerase Rpc34 subunit
70 POLR3Ginteractor100.8441.875RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31
71 POLR3GLinteractor21.0000CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31
72 POLR3Hinteractor140.8572.500RNA_pol_Rbc25 (PF08292, IPR013238): RNA polymerase III subunit Rpc25
SHS2_Rpb7-N (PF03876, IPR005576): SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397
73 POLR3Kinteractor120.8643.455RNA_POL_M_15KD (PF02150, IPR001529): RNA polymerases M/15 Kd subunit
TFIIS_C (PF01096, IPR001222): Transcription factor S-II (TFIIS)
zf-ribbon_3 (PF13248): zinc-ribbon domain
zf-SAP30 (PF13866, IPR025717): SAP30 zinc-finger
74 POU1F1interactor2045.052Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
Lsr2 (PF11774, IPR024412): Lsr2
75 PRR20Ainteractor41.0000PRR20 (PF15708, IPR031439): Proline-rich protein family 20
76 PSMB9interactor140.9620.936Proteasome (PF00227, IPR001353): Proteasome subunit
77 RBPMSprotein found in more fusions110.311342.383RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
78 RECQL5oncoprotein91.0000DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
RecQ5 (PF06959, IPR010716): RecQ helicase protein-like 5 (RecQ5)
SRI (PF08236, IPR013257): SRI (Set2 Rpb1 interacting) domain
TFIIS_M (PF07500, IPR003618): Transcription factor S-II (TFIIS), central domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
RecQ_Zn_bind (PF16124, IPR032284): RecQ zinc-binding
TAtT (PF16811, IPR031823): TRAP transporter T-component
79 RFX6interactor100RFX_DNA_binding (PF02257, IPR003150): RFX DNA-binding domain
SapB_1 (PF05184, IPR007856): Saposin-like type B, region 1
80 RHOXF2interactor80.429152.168DUF367 (PF04034, IPR007177): Domain of unknown function (DUF367)
GRP (PF07172, IPR010800): Glycine rich protein family
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
81 RNF31interactor40.66717.293Auto_anti-p27 (PF06677, IPR009563): Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27)
IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
PUB (PF09409, IPR018997): PUB domain
TF_Zn_Ribbon (PF08271, IPR013137): TFIIB zinc-binding
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain
HOIP-UBA (PF16678, IPR032065): UB-associated-like domain of HOIP or E3 ubiquitin-protein ligase
82 RPAP2interactor170.66930.691NAD_Gly3P_dh_N (PF01210, IPR011128): NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus
RPAP2_Rtr1 (PF04181, IPR007308): Rtr1/RPAP2 family
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
83 RPRD1Binteractor150.68631.415CTD_bind (PF04818, IPR006903): RNA polymerase II-binding domain.
Efg1 (PF10153, IPR019310): rRNA-processing protein Efg1
CTK3 (PF12243, IPR024638): CTD kinase subunit gamma CTK3
CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour
84 SDC2protein found in more fusions200Glycophorin_A (PF01102, IPR001195): Glycophorin A
Syndecan (PF01034, IPR027789): Syndecan domain
DUF3275 (PF11679, IPR021693): Protein of unknown function (DUF3275)
85 SETXinteractor41.0000ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit
AAA_11 (PF13086): AAA domain
AAA_12 (PF13087): AAA domain
86 SMAD3oncoprotein70.26784.314MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
87 SMARCA2suppressor40.167127.472DUF1168 (PF06658, IPR009548): Protein of unknown function (DUF1168)
DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840)
HSA (PF07529, IPR014012, SM00573): HSA
QLQ (PF08880, IPR014978, SM00951): QLQ
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
YL1 (PF05764, IPR008895): YL1 nuclear protein
BRK (PF07533, IPR006576, SM00592): BRK domain
DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052)
EPL1 (PF10513, IPR019542): Enhancer of polycomb-like
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
88 SPAG8interactor100Zip (PF02535, IPR003689): ZIP Zinc transporter
89 SRConcoprotein140.83381.025Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
90 SUPT4H1interactor60.60018.264Spt4 (PF06093, IPR022800): Spt4/RpoE2 zinc finger
91 SUPT5Hinteractor130.7319.533KOW (PF00467, IPR005824, SM00739): KOW motif
Ribonuc_P_40 (PF08584, IPR013893): Ribonuclease P 40kDa (Rpp40) subunit
Spt5-NGN (PF03439, IPR005100): Early transcription elongation factor of RNA pol II, NGN section
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
DUF3912 (PF13051, IPR025023): Protein of unknown function (DUF3912)
92 TCEB3suppressor120.9700.282Elongin_A (PF06881, IPR010684): RNA polymerase II transcription factor SIII (Elongin) subunit A
Med26 (PF08711, IPR017923): TFIIS helical bundle-like domain
93 TRAPPC2interactor31.0000Sedlin_N (PF04628, IPR006722): Sedlin, N-terminal conserved region
94 TRIM23interactor200Arf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family
FemAB (PF02388, IPR003447): FemAB family
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
95 TRIOBPinteractor21.0000FadA (PF09403, IPR018543): Adhesion protein FadA
OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
PH (PF00169, IPR001849, SM00233): PH domain
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
96 UPF2interactor31.0000DDHD (PF02862, IPR004177, SM01127): DDHD domain
DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
MIF4G (PF02854, IPR003890, SM00543): MIF4G domain
Upf2 (PF04050, IPR007193): Up-frameshift suppressor 2
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
SUFU_C (PF12470, IPR024314): Suppressor of Fused Gli/Ci N terminal binding domain
97 XPO1interactor220.3291101.877CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
98 ZBTB32interactor31.0000BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-met (PF12874): Zinc-finger of C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
99 ZNRD1interactor41.0000RecR (PF02132, IPR023628): RecR protein
RNA_POL_M_15KD (PF02150, IPR001529): RNA polymerases M/15 Kd subunit
TFIIS_C (PF01096, IPR001222): Transcription factor S-II (TFIIS)

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