Find Fusion Network

Enter
Fusion ID:
Protein names:


Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins NBAS, VPS13B (from a repository: Wed Aug 7 20:52:51 2019)
Examples

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Circle
Radial
Force Directed
Preset
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)16
The number (and %) of the onco-proteins2 (12.50 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)34 (28.33 %)
The number (and %) of affected PPIs14 (41.18 %)
The number of possible different fusions2
PPI diameter5
PPI radius3
The average degree of PPI3.750
Assortativity coefficient0.0549
The network average Clustering coefficient0.495
The number (and %) of a zero Clustering coefficients5 (31.25 %)
The number (and %) of a zero Betweenness Centrality6 (37.50 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: VPS13B,NBAS All fusions
Proteins found in more fusions HSPB1 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 VPS13Bparental protein4055.000ATG_C (PF09333, IPR015412): Autophagy-related protein C terminal domain
SHR-BD (PF06650, IPR009543): SHR-binding domain of vacuolar-sorting associated protein 13
Chorein_N (PF12624, IPR026854): N-terminal region of Chorein or VPS13
VPS13 (PF16908, IPR031646): Vacuolar sorting-associated protein 13, N-terminal
VPS13_C (PF16909, IPR031645): Vacuolar-sorting-associated 13 protein C-terminal
2 NBASparental protein100.289127.833PMEI (PF04043, IPR006501, SM00856): Plant invertase/pectin methylesterase inhibitor
Sec39 (PF08314, IPR013244): Secretory pathway protein Sec39
SLX9 (PF15341): Ribosome biogenesis protein SLX9
Nbas_N (PF15492, IPR029145): Neuroblastoma-amplified sequence, N terminal
3 AK1interactor100AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
ADK (PF00406, IPR000850): Adenylate kinase
4 CSNK1Einteractor40.33344.000APH (PF01636, IPR002575): Phosphotransferase enzyme family
Pkinase (PF00069, IPR000719): Protein kinase domain
5 DNAJC7interactor2022.000DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
Rapsyn_N (PF10579, IPR019568): Rapsyn N-terminal myristoylation and linker region
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_17 (PF13431): Tetratricopeptide repeat
6 DVL2interactor40.66724.000DEP (PF00610, IPR000591, SM00049): Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)
Dishevelled (PF02377, IPR003351): Dishevelled specific domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
DIX (PF00778, IPR001158, SM00021): DIX domain
Dsh_C (PF12316, IPR024580): Segment polarity protein dishevelled (Dsh) C terminal
7 FAM177A1interactor100Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
Connexin (PF00029, IPR013092, SM00037): Connexin
FAM177 (PF14774, IPR028260): FAM177 family
8 HSPB1oncoprotein31.0000HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
9 NAPGinteractor41.0000SNAP (PF14938): Soluble NSF attachment protein, SNAP
10 NTRK1oncoprotein60.30070.000I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
11 SPACA1interactor100DUF912 (PF06024, IPR009261): Nucleopolyhedrovirus protein of unknown function (DUF912)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
12 STX12interactor60.7332.833PEP-utilisers_N (PF05524, IPR008731): PEP-utilising enzyme, N-terminal
SNARE (PF05739, IPR000727, SM00397): SNARE domain
DUF2776 (PF10951, IPR021240): Protein of unknown function (DUF2776)
Syntaxin_2 (PF14523): Syntaxin-like protein
13 STX18interactor50.8001.333Syntaxin-18_N (PF10496, IPR019529): SNARE-complex protein Syntaxin-18 N-terminus
DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391)
Phage_Integr_2 (PF13009, IPR024965): Putative phage integrase
14 STX6interactor50.9000.500Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal
SNARE (PF05739, IPR000727, SM00397): SNARE domain
15 USE1interactor31.0000Use1 (PF09753, IPR019150): Membrane fusion protein Use1
16 VTI1Binteractor50.9000.500Fusion_gly (PF00523, IPR000776): Fusion glycoprotein F0
V-SNARE (PF05008, IPR007705): Vesicle transport v-SNARE protein N-terminus
V-SNARE_C (PF12352): Snare region anchored in the vesicle membrane C-terminus

B a c k    t o    T o p ⇑