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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)197
The number (and %) of the onco-proteins53 (26.90 %)
The number (and %) of the tumor suppressors17 (8.63 %)
Total number of binary PPIs (saturation %)861 (4.46 %)
The number (and %) of affected PPIs197 (22.88 %)
The number of possible different fusions33
PPI diameter4
PPI radius2
The average degree of PPI8.122
Assortativity coefficient-0.2951
The network average Clustering coefficient0.484
The number (and %) of a zero Clustering coefficients37 (18.78 %)
The number (and %) of a zero Betweenness Centrality62 (31.47 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: FOLH1,NF2 All fusions
Proteins found in more fusions MME (see 1 fusions); CUL4A (see 4 fusions); TSN (see 1 fusions); PRPF19 (see 2 fusions); S100A8 (see 3 fusions); DCAF1 (see 1 fusions); SLC9A3R1 (see 2 fusions); GMDS (see 1 fusions); XRCC4 (see 1 fusions); UBA3 (see 1 fusions); SERBP1 (see 1 fusions); SP1 (see 1 fusions); CHMP1A (see 2 fusions); CD2AP (see 1 fusions); NF2 (see 1 fusions); MVP (see 2 fusions); NF2/CPNE3 (see 2 fusions); KSR1 (see 1 fusions); PRDX1 (see 1 fusions); EZR (see 2 fusions); SEC23B (see 2 fusions); RPL3/RPL13A (see 1 fusions); KDM1A (see 3 fusions); TSG101 (see 2 fusions); AMOTL2 (see 1 fusions); CTH (see 3 fusions); LUC7L3 (see 1 fusions); PARP1 (see 1 fusions); DDB1 (see 4 fusions); RPA1 (see 1 fusions); SLC25A11 (see 1 fusions); SMAD3 (see 3 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 FOLH1parental protein40416.876PA (PF02225, IPR003137): PA domain
Peptidase_M28 (PF04389, IPR007484): Peptidase family M28
TFR_dimer (PF04253, IPR007365): Transferrin receptor-like dimerisation domain
UNC-79 (PF14776): Cation-channel complex subunit UNC-79
2 NF2parental protein1930.03332732.286ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
3 AFG3L2interactor40.6671.667AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
FtsH_ext (PF06480, IPR011546): FtsH Extracellular
Peptidase_M41 (PF01434, IPR000642): Peptidase family M41
TniB (PF05621, IPR008868): Bacterial TniB protein
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
4 AGAP2oncoprotein100ArfGap (PF01412, IPR001164, SM00105): Putative GTPase activating protein for Arf
PH (PF00169, IPR001849, SM00233): PH domain
Ras (PF00071, IPR001806, SM00173): Ras family
Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
5 AKAP8Linteractor50.6002.900AKAP95 (PF04988, IPR007071): A-kinase anchoring protein 95 (AKAP95)
DUF3464 (PF11947, IPR021855): Protein of unknown function (DUF3464)
6 AKT1oncoprotein70.4675.800PH (PF00169, IPR001849, SM00233): PH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
7 AMOToncoprotein110.55613.333FAP (PF07174, IPR010801): Fibronectin-attachment protein (FAP)
Gastrin (PF00918, IPR001651, SM00029): Gastrin/cholecystokinin family
DUF2162 (PF09930, IPR017199): Predicted transporter (DUF2162)
Angiomotin_C (PF12240, IPR024646): Angiomotin C terminal
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
8 AMOTL1interactor80.5716.402NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein
Presenilin (PF01080, IPR001108): Presenilin
Angiomotin_C (PF12240, IPR024646): Angiomotin C terminal
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167
APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain
9 AMOTL2protein found in more fusions70.8001.833HOOK (PF05622, IPR008636): HOOK protein
SlyX (PF04102, IPR007236): SlyX
Angiomotin_C (PF12240, IPR024646): Angiomotin C terminal
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
10 ATAD3Ainteractor40.6671.500AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
DUF3523 (PF12037, IPR021911): Domain of unknown function (DUF3523)
11 ATAD3Binteractor21.0000AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
TsaE (PF02367, IPR003442): Threonylcarbamoyl adenosine biosynthesis protein TsaE
DUF3523 (PF12037, IPR021911): Domain of unknown function (DUF3523)
12 ATP6V1Hinteractor100V-ATPase_H_N (PF03224, IPR004908): V-ATPase subunit H
V-ATPase_H_C (PF11698, IPR011987): V-ATPase subunit H
13 C1orf35interactor100Protamine_P1 (PF00260, IPR000221): Protamine P1
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
MMtag (PF10159, IPR019315): Kinase phosphorylation protein
14 CALML5interactor100EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
15 CAPRIN1interactor40.6671.000DUF1140 (PF06600, IPR009520): Protein of unknown function (DUF1140)
Caprin-1_C (PF12287, IPR022070): Cytoplasmic activation/proliferation-associated protein-1 C term
16 CBR4interactor100adh_short_C2 (PF13561): Enoyl-(Acyl carrier protein) reductase
17 CBSinteractor50.333187.133CBS (PF00571, IPR000644, SM00116): CBS domain
DUF1414 (PF07208, IPR009857): Protein of unknown function (DUF1414)
PALP (PF00291, IPR001926): Pyridoxal-phosphate dependent enzyme
18 CCNB1IP1oncoprotein31.0000MAD (PF05557, IPR008672): Mitotic checkpoint protein
Paramyx_P_V_C (PF03210, IPR004897): Paramyxovirus P/V phosphoprotein C-terminal
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
19 CCNL2interactor40.6671.667Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
20 CD2APprotein found in more fusions50.6672.000SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
betaPIX_CC (PF16523, IPR032409): betaPIX coiled coil
21 CD44suppressor40.5003.000VP4_2 (PF08935, IPR015031): Viral protein VP4 subunit
Xlink (PF00193, IPR000538, SM00445): Extracellular link domain
S36_mt (PF10937, IPR020373): Ribosomal protein S36, mitochondrial
22 CDK1oncoprotein70.3338.719Pkinase (PF00069, IPR000719): Protein kinase domain
23 CDK5oncoprotein200Pkinase (PF00069, IPR000719): Protein kinase domain
24 CHMP1Aprotein found in more fusions60.5003.236Snf7 (PF03357, IPR005024): Snf7
25 CHMP4Binteractor90.32117.833Snf7 (PF03357, IPR005024): Snf7
26 CKAP5interactor50.6670.900HEAT (PF02985, IPR000357): HEAT repeat
PAS_6 (PF08348, IPR013559): YheO-like PAS domain
UME (PF08064, IPR012993, SM00802): UME (NUC010) domain
CLASP_N (PF12348, IPR024395): CLASP N terminal
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
27 CLCC1interactor100MCLC (PF05934, IPR009231): Mid-1-related chloride channel (MCLC)
28 CPNE3protein found in more fusions21.0000C2 (PF00168, IPR000008, SM00239): C2 domain
Copine (PF07002, IPR010734): Copine
29 CPSF6interactor2062.068RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
PRIMA1 (PF16101): Proline-rich membrane anchor 1
30 CTHprotein found in more fusions4014.600Cys_Met_Meta_PP (PF01053, IPR000277): Cys/Met metabolism PLP-dependent enzyme
31 CUL4Aprotein found in more fusions220.195151.036Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
32 DARSinteractor80.42914.422tRNA-synt_2 (PF00152, IPR004364): tRNA synthetases class II (D, K and N)
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
33 DBN1oncoprotein70.28612.167Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region
Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
CAF-1_p150 (PF11600): Chromatin assembly factor 1 complex p150 subunit, N-terminal
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
34 DBTinteractor21.00002-oxoacid_dh (PF00198, IPR001078): 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
Biotin_lipoyl (PF00364, IPR000089): Biotin-requiring enzyme
E3_binding (PF02817, IPR004167): e3 binding domain
HlyD_D23 (PF16576, IPR032317): Barrel-sandwich domain of CusB or HlyD membrane-fusion
35 DCAF1protein found in more fusions120.32727.541DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913)
LisH (PF08513, IPR013720, SM00667): LisH
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
36 DDB1protein found in more fusions140.35931.472CPSF_A (PF03178, IPR004871): CPSF A subunit region
MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term
37 DECR1interactor50.6003.400adh_short_C2 (PF13561): Enoyl-(Acyl carrier protein) reductase
38 DHX15interactor110.45515.882DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
AAA_29 (PF13555): P-loop containing region of AAA domain
39 DHX30interactor50.7001.136Bombolitin (PF08096, IPR012534): Bombolitin family
DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
Dicer_dimer (PF03368, IPR005034): Dicer dimerisation domain
OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold
HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
40 DLATinteractor30.6670.6672-oxoacid_dh (PF00198, IPR001078): 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
Biotin_lipoyl (PF00364, IPR000089): Biotin-requiring enzyme
E3_binding (PF02817, IPR004167): e3 binding domain
Rib_recp_KP_reg (PF05104, IPR007794): Ribosome receptor lysine/proline rich region
Stm1_N (PF09598, IPR019084): Stm1
NICE-1 (PF15845, IPR031698): Cysteine-rich C-terminal 1 family
41 DNAJA1interactor80.39317.217DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
42 DNAJA2interactor80.42911.436DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
43 DNPEPinteractor200Peptidase_M18 (PF02127, IPR001948): Aminopeptidase I zinc metalloprotease (M18)
44 DSC1interactor100Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region
Cadherin_pro (PF08758, IPR014868, SM01055): Cadherin prodomain like
UPF0114 (PF03350, IPR005134): Uncharacterized protein family, UPF0114
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
45 DYNLL1interactor100.36128.500Dynein_light (PF01221, IPR001372): Dynein light chain type 1
46 EIF2S3interactor50.5005.000eIF2_C (PF09173, IPR015256): Initiation factor eIF2 gamma, C terminal
GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
47 EIF3Jinteractor30.6671.400eIF3_subunit (PF08597, IPR013906): Translation initiation factor eIF3 subunit
48 EIF3Minteractor21.0000Death (PF00531, IPR000488, SM00005): Death domain
PCI (PF01399, IPR000717, SM00088): PCI domain
49 EMDinteractor100.36114.241LEM (PF03020, IPR003887, SM00540): LEM domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
50 EPDR1interactor100Ependymin (PF00811, IPR001299, SM00026): Ependymin
51 ERLIN2interactor30.6670.650Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family
DUF4346 (PF14251, IPR025595): Domain of unknown function (DUF4346)
52 EZRprotein found in more fusions90.32119.500DUF106 (PF01956, IPR002809): Integral membrane protein DUF106
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
53 FARSAinteractor100tRNA-synt_2d (PF01409, IPR002319): tRNA synthetases class II core domain (F)
MarR_2 (PF12802): MarR family
54 G3BP2interactor30.6670.250NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
55 GMDSprotein found in more fusions40.333181.833GDP_Man_Dehyd (PF16363, IPR016040): GDP-mannose 4,6 dehydratase
56 GPD2interactor100DAO (PF01266, IPR006076): FAD dependent oxidoreductase
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
DAO_C (PF16901, IPR031656): C-terminal domain of alpha-glycerophosphate oxidase
57 GPS1interactor31.0000RPN7 (PF10602, IPR019585): 26S proteasome subunit RPN7
PCI (PF01399, IPR000717, SM00088): PCI domain
58 GRNoncoprotein21.0000Granulin (PF00396, IPR000118, SM00277): Granulin
Lustrin_cystein (PF14625, IPR028150): Lustrin, cysteine-rich repeated domain
59 GRPEL1interactor70.7332.400GrpE (PF01025, IPR000740): GrpE
60 GRSF1interactor60.4675.452RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence
VWA_N2 (PF16164, IPR032361): VWA N-terminal
61 GTPBP1interactor30.6671.000GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
62 HDAC1suppressor180.19196.460FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
63 HGSinteractor90.30622.407FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
VHS (PF00790, IPR002014, SM00288): VHS domain
EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
Hrs_helical (PF12210, IPR024641): Hepatocyte growth factor-regulated tyrosine kinase substrate
PIEZO (PF15917, IPR031805): Piezo
64 HSD17B4interactor21.0000adh_short (PF00106, IPR002198): short chain dehydrogenase
MaoC_dehydratas (PF01575, IPR002539): MaoC like domain
SCP2 (PF02036, IPR003033): SCP-2 sterol transfer family
MaoC_dehydrat_N (PF13452): N-terminal half of MaoC dehydratase
65 HSPA4interactor190.234236.677Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region
HSP70 (PF00012, IPR013126): Hsp70 protein
TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5
66 HSPA9oncoprotein140.30848.675HSP70 (PF00012, IPR013126): Hsp70 protein
67 HSPH1oncoprotein80.5716.633HSP70 (PF00012, IPR013126): Hsp70 protein
SICA_alpha (PF12887, IPR024290): SICA extracellular alpha domain
68 IGF2BP1oncoprotein40.5000.541RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
KH_1 (PF00013, IPR004088, SM00322): KH domain
KH_4 (PF13083): KH domain
MOEP19 (PF16005, IPR031952): KH-like RNA-binding domain
69 IKBIPinteractor40.5003.000Fez1 (PF06818): Fez1
Occludin_ELL (PF07303, IPR010844): Occludin homology domain
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
SesA (PF17107, IPR031352): N-terminal domain on NACHT_NTPase and P-loop NTPases
70 IRS4interactor60.4676.975CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type)
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence
PH_11 (PF15413): Pleckstrin homology domain
71 IST1interactor31.0000Ist1 (PF03398, IPR005061): Regulator of Vps4 activity in the MVB pathway
72 KDM1Aprotein found in more fusions90.39313.900Amino_oxidase (PF01593, IPR002937): Flavin containing amine oxidoreductase
CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
SWIRM (PF04433, IPR007526): SWIRM domain
DUF4298 (PF14131, IPR025384): Domain of unknown function (DUF4298)
73 KPNA2interactor40.6672.000Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
IBB (PF01749, IPR002652): Importin beta binding domain
Arm_3 (PF16186, IPR032413): Atypical Arm repeat
74 KSR1oncoprotein31.0000Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
KSR1-SAM (PF13543, IPR025561): SAM like domain present in kinase suppressor RAS 1
75 LANCL2interactor30.6670.069Glyco_hydro_127 (PF07944, IPR012878): Beta-L-arabinofuranosidase, GH127
LANC_like (PF05147, IPR007822): Lanthionine synthetase C-like protein
76 LATS1suppressor70.6675.333Cas_Cas6 (PF01881, IPR010156): CRISPR associated protein Cas6
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
77 LATS2suppressor90.7143.833Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
78 LEMD2interactor21.0000LEM (PF03020, IPR003887, SM00540): LEM domain
MSC (PF09402, IPR018996): Man1-Src1p-C-terminal domain
79 LIG3interactor110.6916.713DNA_ligase_A_C (PF04679, IPR012309): ATP dependent DNA ligase C terminal region
DNA_ligase_A_M (PF01068, IPR012310): ATP dependent DNA ligase domain
DNA_ligase_A_N (PF04675, IPR012308): DNA ligase N terminus
Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein
zf-PARP (PF00645, IPR001510): Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
HD_2 (PF12917, IPR027366): HD containing hydrolase-like enzyme
Synaptonemal_3 (PF15191, IPR028145): Synaptonemal complex central element protein 3
LIG3_BRCT (PF16759, IPR031916): DNA ligase 3 BRCT domain
80 LIN7Cinteractor70.5719.000His_Phos_2 (PF00328, IPR000560): Histidine phosphatase superfamily (branch 2)
L27 (PF02828, IPR014775, SM00569): L27 domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
81 LPCAT1interactor100JmjN (PF02375, IPR003349, SM00545): jmjN domain
Acyltransferase (PF01553, IPR002123, SM00563): Acyltransferase
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
82 LSM12interactor100AD (PF09793, IPR019181, SM00995): Anticodon-binding domain
83 LUC7L3protein found in more fusions50.5000.969LUC7 (PF03194, IPR004882): LUC7 N_terminus
Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
DDRGK (PF09756, IPR019153, SM01128): DDRGK domain
84 MC1Rinteractor21.00007tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
7tm_4 (PF13853): Olfactory receptor
85 MED28interactor31.0000cwf21 (PF08312, IPR013170, SM01115): cwf21 domain
Med28 (PF11594, IPR021640): Mediator complex subunit 28
86 MMEsuppressor60.10053.781Peptidase_M13 (PF01431, IPR018497): Peptidase family M13
Peptidase_M13_N (PF05649, IPR008753): Peptidase family M13
87 MOV10interactor370.126450.533AAA_12 (PF13087): AAA domain
AAA_30 (PF13604): AAA domain
88 MPP2interactor21.0000L27 (PF02828, IPR014775, SM00569): L27 domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
SH3_2 (PF07653, IPR011511): Variant SH3 domain
Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase
89 MPP6interactor21.0000L27 (PF02828, IPR014775, SM00569): L27 domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
SH3_2 (PF07653, IPR011511): Variant SH3 domain
Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase
90 MTAPsuppressor100PNP_UDP_1 (PF01048, IPR000845): Phosphorylase superfamily
91 MTPAPinteractor40.5001.800PAP_assoc (PF03828, IPR002058): Cid1 family poly A polymerase
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
tRNA_NucTransf2 (PF09249, IPR015329): tRNA nucleotidyltransferase, second domain
92 MTTPinteractor100Vitellogenin_N (PF01347, IPR001747, SM00638): Lipoprotein amino terminal region
93 MVPoncoprotein50.5003.000Vault (PF01505, IPR002499): Major Vault Protein repeat
DUF2543 (PF10820, IPR020251): Protein of unknown function (DUF2543)
MVP_shoulder (PF11978, IPR021870): Shoulder domain
94 NIT1interactor40.6671.000CN_hydrolase (PF00795, IPR003010): Carbon-nitrogen hydrolase
95 NXF1interactor410.094594.633NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding
TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
96 OR4X1interactor1007tm_4 (PF13853): Olfactory receptor
97 PABPC4interactor140.47332.790ApbA_C (PF08546, IPR013752): Ketopantoate reductase PanE/ApbA C terminal
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain
HHV-5_US34A (PF17087, IPR031384): Herpesvirus US34A protein family
98 PANX1interactor100Innexin (PF00876, IPR000990): Innexin
Pannexin_like (PF12534, IPR021040): Pannexin-like TM region of LRRC8
99 PARP1suppressor200.36372.202BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
PADR1 (PF08063, IPR012982): PADR1 (NUC008) domain
PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain
PARP_reg (PF02877, IPR004102): Poly(ADP-ribose) polymerase, regulatory domain
WGR (PF05406, IPR008893, SM00773): WGR domain
zf-PARP (PF00645, IPR001510): Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
100 PDCD6oncoprotein100.30619.736EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
101 PDCD6IPinteractor110.26731.067BRO1 (PF03097, IPR004328, SM01041): BRO1-like domain
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
ALIX_LYPXL_bnd (PF13949, IPR025304): ALIX V-shaped domain binding to HIV
102 PDHXinteractor40.6671.6672-oxoacid_dh (PF00198, IPR001078): 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
Biotin_lipoyl (PF00364, IPR000089): Biotin-requiring enzyme
E3_binding (PF02817, IPR004167): e3 binding domain
103 PEF1interactor40.6671.167EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
104 PGAM5interactor21.0000His_Phos_1 (PF00300, IPR013078, SM00855): Histidine phosphatase superfamily (branch 1)
105 PHBsuppressor80.32116.067Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family
DUF4290 (PF14123, IPR025632): Domain of unknown function (DUF4290)
106 PIP4K2Cinteractor200PIP5K (PF01504, IPR002498): Phosphatidylinositol-4-phosphate 5-Kinase
107 PNKPinteractor150.41047.448PNK3P (PF08645, IPR013954): Polynucleotide kinase 3 phosphatase
AAA_33 (PF13671): AAA domain
108 PPP1R8interactor21.0000FHA (PF00498, IPR000253, SM00240): FHA domain
109 PRDX1oncoprotein60.5002.667AhpC-TSA (PF00578, IPR000866): AhpC/TSA family
1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin
110 PREBinteractor100WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
111 PRKAG2interactor100CBS (PF00571, IPR000644, SM00116): CBS domain
112 PRKCAinteractor90.35716.088C2 (PF00168, IPR000008, SM00239): C2 domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
113 PRPF19protein found in more fusions100.52810.325Prp19 (PF08606, IPR013915): Prp19/Pso4-like
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
U-box (PF04564, IPR003613, SM00504): U-box domain
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
114 PRPF38Binteractor100PRP38 (PF03371, IPR005037): PRP38 family
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
115 PXNoncoprotein40.5002.069LIM (PF00412, IPR001781, SM00132): LIM domain
Paxillin (PF03535): Paxillin family
116 PYCR2interactor100ApbA (PF02558, IPR013332): Ketopantoate reductase PanE/ApbA
F420_oxidored (PF03807, IPR028939): NADP oxidoreductase coenzyme F420-dependent
P5CR_dimer (PF14748, IPR029036): Pyrroline-5-carboxylate reductase dimerisation
117 PYGO2interactor80.5245.108PHD (PF00628, IPR019787, SM00249): PHD-finger
118 RARSinteractor50.6004.000Arg_tRNA_synt_N (PF03485, IPR005148, SM01016): Arginyl tRNA synthetase N terminal domain
DALR_1 (PF05746, IPR008909, SM00836): DALR anticodon binding domain
DivIC (PF04977, IPR007060): Septum formation initiator
tRNA-synt_1d (PF00750, IPR015945): tRNA synthetases class I (R)
Mto2_bdg (PF12808, IPR024545): Micro-tubular organiser Mto1 C-term Mto2-binding region
119 RBBP4oncoprotein90.36117.000eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein
CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
120 RCC2oncoprotein100RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat
RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
121 RFC1interactor80.6076.638AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
GAGA_bind (PF06217, IPR010409): GAGA binding protein-like family
Nexin_C (PF08628, IPR013937): Sorting nexin C terminal
RFC1 (PF08519, IPR013725): Replication factor RFC1 C terminal domain
DUF2316 (PF10078, IPR018757): Uncharacterized protein conserved in bacteria (DUF2316)
122 RFC3interactor50.7001.348CHB_HEX (PF03173, IPR004866, SM01081): Putative carbohydrate binding domain
DNA_pol3_delta (PF06144, IPR010372): DNA polymerase III, delta subunit
Rep_fac_C (PF08542, IPR013748): Replication factor C C-terminal domain
DNA_pol3_delta2 (PF13177): DNA polymerase III, delta subunit
123 RIT1interactor100Ras (PF00071, IPR001806, SM00173): Ras family
124 RNF166interactor70.38115.500zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding
zinc-ribbons_6 (PF07191, IPR010807): zinc-ribbons
Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
zinc_ribbon_2 (PF13240, IPR026870): zinc-ribbon domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain
125 RPA1suppressor370.202337.177Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain
Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain
126 RPA2oncoprotein350.222293.501RPA_C (PF08784, IPR014892): Replication protein A C terminal
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2
127 RPL10suppressor310.335269.195Ribosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e
128 RPL13interactor200.71126.374Ribosomal_L13e (PF01294, IPR001380): Ribosomal protein L13e
129 RPL13Aprotein found in more fusions190.8367.758Ribosomal_L13 (PF00572, IPR005822): Ribosomal protein L13
130 RPL14interactor200.70534.944KOW (PF00467, IPR005824, SM00739): KOW motif
Ribosomal_L14e (PF01929, IPR002784): Ribosomal protein L14
UPF0688 (PF15772, IPR031530): UPF0688 family
131 RPL15interactor220.69725.390Ribosomal_L15e (PF00827, IPR000439): Ribosomal L15
132 RPL18interactor200.79510.714Ribosomal_L18 (PF17135): Ribosomal protein 60S L18 and 50S L18e
133 RPL18Ainteractor200.75824.425Ribosomal_L18A (PF01775, IPR023573): Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A
134 RPL3protein found in more fusions180.81716.600Ribosomal_L3 (PF00297, IPR000597): Ribosomal protein L3
135 RPL4interactor210.67633.717Ribosomal_L4 (PF00573, IPR002136): Ribosomal protein L4/L1 family
Ribos_L4_asso_C (PF14374, IPR025755): 60S ribosomal protein L4 C-terminal domain
136 RPL8interactor180.83710.473Ribosomal_L2 (PF00181, IPR022666): Ribosomal Proteins L2, RNA binding domain
Ribosomal_L2_C (PF03947, IPR022669): Ribosomal Proteins L2, C-terminal domain
137 RPS2interactor220.63645.187Ribosomal_S5 (PF00333, IPR013810): Ribosomal protein S5, N-terminal domain
Ribosomal_S5_C (PF03719, IPR005324): Ribosomal protein S5, C-terminal domain
138 RPS3interactor250.507806.990KH_2 (PF07650, IPR004044): KH domain
Ribosomal_S3_C (PF00189, IPR001351): Ribosomal protein S3, C-terminal domain
139 RPS3Ainteractor230.63642.302Ribosomal_S3Ae (PF01015, IPR001593): Ribosomal S3Ae family
140 RPS4Xinteractor200.70047.756KOW (PF00467, IPR005824, SM00739): KOW motif
Ribosomal_S4e (PF00900, IPR013845): Ribosomal family S4e
RS4NT (PF08071, IPR013843): RS4NT (NUC023) domain
S4 (PF01479, IPR002942, SM00363): S4 domain
40S_S4_C (PF16121, IPR032277): 40S ribosomal protein S4 C-terminus
141 RPS5interactor230.61346.033Ribosomal_S7 (PF00177, IPR023798): Ribosomal protein S7p/S5e
142 RPS7interactor200.74721.804Ribosomal_S7e (PF01251, IPR000554): Ribosomal protein S7e
143 S100A8oncoprotein31.0000S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
144 S100A9oncoprotein90.39313.500S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
145 SARS2interactor100tRNA-synt_2b (PF00587, IPR002314): tRNA synthetase class II core domain (G, H, P, S and T)
DUF2312 (PF10073, IPR018753): Uncharacterized protein conserved in bacteria (DUF2312)
DUF4445 (PF14574, IPR027980): Domain of unknown function (DUF4445)
146 SCHIP1interactor200SCHIP-1 (PF10148, IPR015649): Schwannomin-interacting protein 1
147 SDCBPinteractor50.5005.000PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
148 SEC23Bprotein found in more fusions31.0000Gelsolin (PF00626, IPR007123): Gelsolin repeat
Sec23_BS (PF08033, IPR012990): Sec23/Sec24 beta-sandwich domain
Sec23_helical (PF04815, IPR006900): Sec23/Sec24 helical domain
Sec23_trunk (PF04811, IPR006896): Sec23/Sec24 trunk domain
zf-Sec23_Sec24 (PF04810, IPR006895): Sec23/Sec24 zinc finger
149 SERBP1protein found in more fusions51.0000HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family
FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
150 SERPINB3oncoprotein100Serpin (PF00079, IPR023796, SM00093): Serpin (serine protease inhibitor)
151 SF3B4interactor40.6671.667RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
152 SFXN2interactor30.6671.000Mtc (PF03820, IPR004686): Tricarboxylate carrier
153 SGSM3interactor30.6670.500RUN (PF02759, IPR004012, SM00593): RUN domain
RabGAP-TBC (PF00566, IPR000195, SM00164): Rab-GTPase-TBC domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
154 SH3GL1oncoprotein40.6671.000BAR (PF03114, IPR004148, SM00721): BAR domain
PhnG (PF06754, IPR009609): Phosphonate metabolism protein PhnG
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
155 SLC25A1interactor31.0000Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
156 SLC25A11protein found in more fusions31.0000Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
157 SLC25A12interactor30.6670.500Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
158 SLC25A13interactor100Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
159 SLC25A22interactor21.0000Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
DUF4257 (PF14074, IPR025353): Protein of unknown function (DUF4257)
160 SLC25A3interactor90.36119.302Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
161 SLC25A5interactor120.69712.076Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
162 SLC25A6interactor30.6670.333Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
163 SLC33A1interactor100Acatn (PF13000, IPR024371): Acetyl-coenzyme A transporter 1
164 SLC9A3R1suppressor80.28688.375EBP50_C (PF09007, IPR015098): EBP50, C-terminal
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
165 SMAD3oncoprotein150.23153.791MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
166 SMC1Aoncoprotein70.8001.500SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
167 SMC3oncoprotein60.5336.167SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
168 SOS1oncoprotein100Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
PH (PF00169, IPR001849, SM00233): PH domain
RasGEF (PF00617, IPR001895, SM00147): RasGEF domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
RasGEF_N (PF00618, IPR000651, SM00229): RasGEF N-terminal motif
169 SP1protein found in more fusions120.29129.086zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding
Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
Miga (PF10265, IPR019392): Mitoguardin
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
170 SPTBN1suppressor70.3816.375CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
COG2 (PF06148, IPR024602): COG (conserved oligomeric Golgi) complex component, COG2
DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
Spectrin (PF00435, IPR002017): Spectrin repeat
PH_9 (PF15410): Pleckstrin homology domain
171 SRPRAinteractor30.6670.667SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
SRP54 (PF00448, IPR000897, SM00962): SRP54-type protein, GTPase domain
SRP54_N (PF02881, IPR013822, SM00963): SRP54-type protein, helical bundle domain
172 SRRM2interactor130.26943.833cwf21 (PF08312, IPR013170, SM01115): cwf21 domain
DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
Pap_E4 (PF02711, IPR003861): E4 protein
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
CTD (PF12815, IPR024945, SM01104): Spt5 C-terminal nonapeptide repeat binding Spt4
DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614)
173 SSRP1interactor60.8001.952Rtt106 (PF08512, IPR013719): Histone chaperone Rttp106-like
SSrecog (PF03531, IPR024954): Structure-specific recognition protein (SSRP1)
YABBY (PF04690, IPR006780): YABBY protein
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
DUF3987 (PF13148, IPR025048): Protein of unknown function (DUF3987)
CAML (PF14963, IPR016719): Calcium signal-modulating cyclophilin ligand
CCDC106 (PF15794, IPR031591): Coiled-coil domain-containing protein 106
Coilin_N (PF15862, IPR031722): Coilin N-terminus
174 SUPT16Hinteractor130.51517.225Nop14 (PF04147, IPR007276): Nop14-like family
Peptidase_M24 (PF00557, IPR001714): Metallopeptidase family M24
Rtt106 (PF08512, IPR013719): Histone chaperone Rttp106-like
SPT16 (PF08644, IPR013953): FACT complex subunit (SPT16/CDC68)
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
FACT-Spt16_Nlob (PF14826, IPR029148): FACT complex subunit SPT16 N-terminal lobe domain
175 TAF15oncoprotein60.6672.167API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5)
GRP (PF07172, IPR010800): Glycine rich protein family
Presenilin (PF01080, IPR001108): Presenilin
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
176 TBL2suppressor30.6670.667eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
FdsD (PF11390, IPR021074): NADH-dependant formate dehydrogenase delta subunit FdsD
177 TBPinteractor41.0000TBP (PF00352, IPR000814): Transcription factor TFIID (or TATA-binding protein, TBP)
EPL1 (PF10513, IPR019542): Enhancer of polycomb-like
Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal
178 TFCP2interactor50.4005.667CP2 (PF04516, IPR007604): CP2 transcription factor
DUF2967 (PF11179, IPR021349): Protein of unknown function (DUF2967)
179 TGM3suppressor100Transglut_C (PF00927, IPR008958): Transglutaminase family, C-terminal ig like domain
Transglut_N (PF00868, IPR001102): Transglutaminase family
Transglut_core (PF01841, IPR002931, SM00460): Transglutaminase-like superfamily
180 TMPOinteractor70.5717.238LEM (PF03020, IPR003887, SM00540): LEM domain
Thymopoietin (PF08198, IPR013146): Thymopoietin protein
LAP2alpha (PF11560, IPR021623): Lamina-associated polypeptide 2 alpha
181 TOP1oncoprotein70.5247.905DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
Topoisom_I (PF01028, IPR013500): Eukaryotic DNA topoisomerase I, catalytic core
Topoisom_I_N (PF02919, IPR008336): Eukaryotic DNA topoisomerase I, DNA binding fragment
MCM_bind (PF09739, IPR019140): Mini-chromosome maintenance replisome factor
Sox_N (PF12444, IPR022151): Sox developmental protein N terminal
Topo_C_assoc (PF14370, IPR025834): C-terminal topoisomerase domain
DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614)
TonB_N (PF16031): TonB N-terminal region
182 TPRoncoprotein70.4298.800Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus
ZapB (PF06005, IPR009252): Cell division protein ZapB
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
IncA (PF04156, IPR007285): IncA protein
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
XhlA (PF10779, IPR019715): Haemolysin XhlA
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein
DUF3373 (PF11853, IPR021803): Protein of unknown function (DUF3373)
DUF4107 (PF13389, IPR025180): Protein of unknown function (DUF4107)
JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II
CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour
DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
183 TRIM21interactor31.0000DUF313 (PF03754, IPR005508): Domain of unknown function (DUF313)
SPRY (PF00622, IPR003877, SM00449): SPRY domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
Prok-RING_1 (PF14446): Prokaryotic RING finger family 1
zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
184 TSG101suppressor110.28925.569APG6 (PF04111, IPR007243): Autophagy protein Apg6
Laminin_II (PF06009, IPR010307): Laminin Domain II
UEV (PF05743, IPR008883): UEV domain
Vps23_core (PF09454, IPR017916): Vps23 core domain
185 TSNprotein found in more fusions200Translin (PF01997, IPR002848): Translin family
186 TUBA1Cinteractor150.21068.008Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
187 TUBB4Ainteractor40.5002.500Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
188 UBA3protein found in more fusions31.0000E2_bind (PF08825, IPR014929): E2 binding domain
ThiF (PF00899, IPR000594): ThiF family
189 VTA1interactor30.6671.667Vta1 (PF04652): Vta1 like
190 WBP2interactor21.0000GRAM (PF02893, IPR004182, SM00568): GRAM domain
Vps36_ESCRT-II (PF11605, IPR021648): Vacuolar protein sorting protein 36 Vps36
191 WWC1interactor90.38915.469APG6 (PF04111, IPR007243): Autophagy protein Apg6
bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor
C2 (PF00168, IPR000008, SM00239): C2 domain
Sec2p (PF06428, IPR009449): GDP/GTP exchange factor Sec2p
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Spore_III_AB (PF09548, IPR014198): Stage III sporulation protein AB (spore_III_AB)
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
WW (PF00397, IPR001202, SM00456): WW domain
192 XRCC1interactor70.8102.667BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
SPX (PF03105, IPR004331): SPX domain
XRCC1_N (PF01834, IPR002706): XRCC1 N terminal domain
BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
193 XRCC4protein found in more fusions51.0000XRCC4 (PF06632, IPR010585): DNA double-strand break repair and V(D)J recombination protein XRCC4
194 XRCC5suppressor170.383167.256Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain
Ku_PK_bind (PF08785, IPR014893): Ku C terminal domain like
195 XRCC6oncoprotein170.37552.066Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain
SAP (PF02037, IPR003034, SM00513): SAP domain
196 YAP1suppressor150.29565.993Bindin (PF02084, IPR000775): Bindin
WW (PF00397, IPR001202, SM00456): WW domain
GspL_C (PF12693, IPR025691): GspL periplasmic domain
FAM181 (PF15238, IPR029359): FAM181
197 ZBTB10interactor100BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Ribosomal_L37ae (PF01780, IPR002674): Ribosomal L37ae protein family
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain

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