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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)115
The number (and %) of the onco-proteins28 (24.35 %)
The number (and %) of the tumor suppressors9 (7.83 %)
Total number of binary PPIs (saturation %)757 (11.55 %)
The number (and %) of affected PPIs114 (15.06 %)
The number of possible different fusions22
PPI diameter5
PPI radius3
The average degree of PPI12.591
Assortativity coefficient-0.1195
The network average Clustering coefficient0.511
The number (and %) of a zero Clustering coefficients13 (11.30 %)
The number (and %) of a zero Betweenness Centrality19 (16.52 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: NDUFS4,NR2C2 All fusions
Proteins found in more fusions ITSN2 (see 5 fusions); TAB2 (see 1 fusions); TRAF6 (see 1 fusions); APP (see 5 fusions); ATP1A1/VDAC3 (see 2 fusions); HSP90AA1 (see 6 fusions); TRIM28 (see 1 fusions); DCAF1 (see 1 fusions); HDAC4 (see 1 fusions); PARK2 (see 1 fusions); CD2AP (see 1 fusions); NDUFS3 (see 2 fusions); HNF4A (see 1 fusions); ALDOA (see 2 fusions); KDM1A (see 3 fusions); SMARCC1 (see 2 fusions); EED/TRIM28 (see 1 fusions); ATP5A1 (see 1 fusions); DDB1 (see 4 fusions); PRPF40A (see 2 fusions); CHD4 (see 6 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 NDUFS4parental protein730.1783887.384ETC_C1_NDUFA4 (PF04800, IPR006885): ETC complex I subunit conserved region
2 NR2C2parental protein410.1272745.544Flagellin_N (PF00669, IPR001029): Bacterial flagellin N-terminal helical region
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
3 ABCD3interactor50.8000.284ABC_membrane_2 (PF06472, IPR010509): ABC transporter transmembrane region 2
ABC_tran (PF00005, IPR003439): ABC transporter
4 AFDNoncoprotein2032.617DIL (PF01843, IPR018444, SM01132): DIL domain
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
FHA (PF00498, IPR000253, SM00240): FHA domain
MAP7 (PF05672, IPR008604): MAP7 (E-MAP-115) family
MAS20 (PF02064, IPR002056): MAS20 protein import receptor
Pap_E4 (PF02711, IPR003861): E4 protein
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal
Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain
ARGLU (PF15346): Arginine and glutamate-rich 1
5 ALDOAprotein found in more fusions60.30081.977Glycolytic (PF00274, IPR000741): Fructose-bisphosphate aldolase class-I
6 ALDOCinteractor21.0000Glycolytic (PF00274, IPR000741): Fructose-bisphosphate aldolase class-I
7 APPprotein found in more fusions220.233768.486APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
8 ARoncoprotein120.40044.383Androgen_recep (PF02166, IPR001103): Androgen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
9 ATAD3Ainteractor80.321238.359AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
DUF3523 (PF12037, IPR021911): Domain of unknown function (DUF3523)
10 ATP1A1protein found in more fusions120.6825.333Cation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus
Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus
E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
Tetraspannin (PF00335, IPR018499): Tetraspanin family
Cation_ATPase (PF13246): Cation transport ATPase (P-type)
11 ATP2A2interactor31.0000Cation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus
Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus
E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
HAD (PF12710): haloacid dehalogenase-like hydrolase
Cation_ATPase (PF13246): Cation transport ATPase (P-type)
12 ATP5A1protein found in more fusions150.64862.709ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain
ATP-synt_ab_C (PF00306, IPR000793): ATP synthase alpha/beta chain, C terminal domain
ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain
13 ATP5C1interactor160.61720.520ATP-synt (PF00231, IPR000131): ATP synthase
ACT_4 (PF13291, IPR002912): ACT domain
14 ATP5F1interactor200.447225.231Mt_ATP-synt_B (PF05405, IPR008688): Mitochondrial ATP synthase B chain precursor (ATP-synt_B)
DUF2105 (PF09878, IPR019212): Predicted membrane protein (DUF2105)
15 ATP5POinteractor180.56931.594OSCP (PF00213, IPR000711): ATP synthase delta (OSCP) subunit
16 ATP6V0D1interactor180.47755.729vATP-synt_AC39 (PF01992, IPR002843): ATP synthase (C/AC39) subunit
17 CACNA2D1interactor100dCache_1 (PF02743, IPR004010): Cache domain
VGCC_alpha2 (PF08473, IPR013680): Neuronal voltage-dependent calcium channel alpha 2acd
VWA (PF00092, IPR002035, SM00327): von Willebrand factor type A domain
VWA_N (PF08399, IPR013608): VWA N-terminal
VWA_2 (PF13519, IPR002035): von Willebrand factor type A domain
18 CD2APprotein found in more fusions200SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
betaPIX_CC (PF16523, IPR032409): betaPIX coiled coil
19 CHD4oncoprotein110.8223.967CDC27 (PF09507, IPR019038): DNA polymerase subunit Cdc27
CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain
CHDNT (PF08073, IPR012958): CHDNT (NUC034) domain
Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
DTHCT (PF08070, IPR012542): DTHCT (NUC029) region
DUF1086 (PF06461, IPR009462, SM01146): Domain of Unknown Function (DUF1086)
DUF1087 (PF06465, IPR009463, SM01147): Domain of Unknown Function (DUF1087)
PHD (PF00628, IPR019787, SM00249): PHD-finger
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
FAM176 (PF14851): FAM176 family
Coilin_N (PF15862, IPR031722): Coilin N-terminus
20 COX15interactor70.7622.301COX15-CtaA (PF02628, IPR003780): Cytochrome oxidase assembly protein
Peptidase_S3 (PF00944, IPR000930): Alphavirus core protein
21 COX4I1interactor130.55122.119COX4 (PF02936, IPR004203): Cytochrome c oxidase subunit IV
22 COX6B1interactor100.6946.169COX6B (PF02297, IPR003213): Cytochrome oxidase c subunit VIb
23 COX7A2Linteractor50.7000.700COX7a (PF02238, IPR003177): Cytochrome c oxidase subunit VII
24 CUL4Boncoprotein110.309237.498Cullin (PF00888, IPR001373, SM00182): Cullin family
EBP50_C (PF09007, IPR015098): EBP50, C-terminal
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
PG_binding_4 (PF12229, IPR022029): Putative peptidoglycan binding domain
MDFI (PF15316, IPR026134): MyoD family inhibitor
25 CYC1interactor200.363100.287Cytochrom_C1 (PF02167, IPR002326): Cytochrome C1 family
26 DCAF1protein found in more fusions70.60021.527DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913)
LisH (PF08513, IPR013720, SM00667): LisH
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
27 DDB1protein found in more fusions90.53613.593CPSF_A (PF03178, IPR004871): CPSF A subunit region
MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term
28 DLATinteractor50.6001.7302-oxoacid_dh (PF00198, IPR001078): 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
Biotin_lipoyl (PF00364, IPR000089): Biotin-requiring enzyme
E3_binding (PF02817, IPR004167): e3 binding domain
Rib_recp_KP_reg (PF05104, IPR007794): Ribosome receptor lysine/proline rich region
Stm1_N (PF09598, IPR019084): Stm1
NICE-1 (PF15845, IPR031698): Cysteine-rich C-terminal 1 family
29 DNAJC30interactor40.5005.100DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
30 DNMT1suppressor110.8223.315BAH (PF01426, IPR001025, SM00439): BAH domain
DMAP_binding (PF06464, IPR010506, SM01137): DMAP1-binding Domain
DNA_methylase (PF00145, IPR001525): C-5 cytosine-specific DNA methylase
zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain
DNMT1-RFD (PF12047, IPR022702): Cytosine specific DNA methyltransferase replication foci domain
31 EEDsuppressor200.263462.318WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
32 ESR1suppressor210.247524.178Oest_recep (PF02159, IPR001292): Oestrogen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
33 FOXL1oncoprotein100Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
34 FUBP1oncoprotein60.333121.739DUF1897 (PF09005, IPR015096): Domain of unknown function (DUF1897)
KH_1 (PF00013, IPR004088, SM00322): KH domain
CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
35 FUBP3interactor50.50085.923DUF1897 (PF09005, IPR015096): Domain of unknown function (DUF1897)
KH_1 (PF00013, IPR004088, SM00322): KH domain
36 GOLT1Binteractor320.415415.713Got1 (PF04178, IPR007305): Got1/Sft2-like family
37 HDAC1suppressor170.48353.182FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
38 HDAC3suppressor140.44947.572Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
39 HDAC4oncoprotein100.472246.570Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
40 HNF4Asuppressor51.0000zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
41 HSP90AA1oncoprotein140.295472.630HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
42 ITSN2protein found in more fusions40.333202.564C2 (PF00168, IPR000008, SM00239): C2 domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
SH3_9 (PF14604, IPR001452): Variant SH3 domain
MRP-S26 (PF14943, IPR026140): Mitochondrial ribosome subunit S26
VIR_N (PF15912, IPR031801): Virilizer, N-terminal
PH_13 (PF16652, IPR001849): Pleckstrin homology domain
43 JAZF1oncoprotein100ARS2 (PF04959, IPR007042): Arsenite-resistance protein 2
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain
zf-C2H2_aberr (PF17017, IPR031514): Aberrant zinc-finger
44 KDM1Aprotein found in more fusions170.4331175.412Amino_oxidase (PF01593, IPR002937): Flavin containing amine oxidoreductase
CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
SWIRM (PF04433, IPR007526): SWIRM domain
DUF4298 (PF14131, IPR025384): Domain of unknown function (DUF4298)
45 KLHL7interactor200BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_6 (PF13964): Kelch motif
46 M6PRinteractor21.0000Man-6-P_recep (PF02157, IPR028927): Mannose-6-phosphate receptor
47 MARC1interactor50.4006.638MOSC (PF03473, IPR005302): MOSC domain
MOSC_N (PF03476, IPR005303): MOSC N-terminal beta barrel domain
48 MGST3interactor31.0000MAPEG (PF01124, IPR001129): MAPEG family
49 MRPL15interactor80.42925.704Ribosomal_L27A (PF00828, IPR021131): Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
50 MT-ND5interactor90.9720.083NADH5_C (PF06455, IPR010934): NADH dehydrogenase subunit 5 C-terminus
Proton_antipo_M (PF00361, IPR001750): Proton-conducting membrane transporter
Proton_antipo_N (PF00662, IPR001516): NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus
51 MTA1oncoprotein90.9171.650BAH (PF01426, IPR001025, SM00439): BAH domain
ELM2 (PF01448, IPR000949): ELM2 domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
GATA (PF00320, IPR000679, SM00401): GATA zinc finger
52 ND1interactor80.9640.083NA
53 ND4interactor60.9330.083NA
54 NDUFA11interactor210.66716.0377kD_coat (PF02495, IPR003411): 7kD viral coat protein
Tim17 (PF02466, IPR003397): Tim17/Tim22/Tim23/Pmp24 family
55 NDUFA12interactor350.455146.785NDUFA12 (PF05071, IPR007763): NADH ubiquinone oxidoreductase subunit NDUFA12
56 NDUFA13interactor140.8683.224GRIM-19 (PF06212, IPR009346): GRIM-19 protein
57 NDUFA2interactor170.64729.252L51_S25_CI-B8 (PF05047, IPR007741, SM00916): Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain
58 NDUFA4interactor330.433188.831B12D (PF06522, IPR010530): NADH-ubiquinone reductase complex 1 MLRQ subunit
59 NDUFA7interactor140.527179.016CI-B14_5a (PF07347, IPR009947): NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a)
60 NDUFA8interactor290.466512.145CHCH (PF06747, IPR010625): CHCH domain
Pet191_N (PF10203, IPR018793): Cytochrome c oxidase assembly protein PET191
Cdd1 (PF11731, IPR021725): Pathogenicity locus
61 NDUFA9interactor330.502102.269Epimerase (PF01370, IPR001509): NAD dependent epimerase/dehydratase family
62 NDUFAF3interactor120.652104.314DUF498 (PF04430, IPR007523): Protein of unknown function (DUF498/DUF598)
63 NDUFB10interactor140.65914.586NDUFB10 (PF10249, IPR019377): NADH-ubiquinone oxidoreductase subunit 10
64 NDUFB4interactor170.58155.006NDUF_B4 (PF07225, IPR009866): NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4)
65 NDUFB5interactor120.8332.531NDUF_B5 (PF09781, IPR019173): NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit
66 NDUFB8interactor180.52946.914NDUF_B8 (PF05821, IPR008699): NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8)
67 NDUFS1interactor300.508527.030NADH_dhqG_C (PF09326, IPR015405): NADH-ubiquinone oxidoreductase subunit G, C-terminal
Fer4 (PF00037, IPR001450): 4Fe-4S binding domain
Molybdopterin (PF00384, IPR006656): Molybdopterin oxidoreductase
NADH-G_4Fe-4S_3 (PF10588, IPR019574, SM00929): NADH-ubiquinone oxidoreductase-G iron-sulfur binding region
Fer2_4 (PF13510): 2Fe-2S iron-sulfur cluster binding domain
68 NDUFS2interactor230.577125.300Complex1_49kDa (PF00346, IPR001135): Respiratory-chain NADH dehydrogenase, 49 Kd subunit
NiFeSe_Hases (PF00374, IPR001501): Nickel-dependent hydrogenase
69 NDUFS3protein found in more fusions350.467143.928Complex1_30kDa (PF00329, IPR001268): Respiratory-chain NADH dehydrogenase, 30 Kd subunit
70 NDUFS5interactor280.53767.557Ndufs5 (PF10200, IPR019342): NADH:ubiquinone oxidoreductase, NDUFS5-15kDa
71 NDUFS6interactor230.67231.665Thiolase_C (PF02803, IPR020617): Thiolase, C-terminal domain
zf-CHCC (PF10276, IPR019401, SM00400): Zinc-finger domain
72 NDUFS7interactor200.7848.665Oxidored_q6 (PF01058, IPR006137): NADH ubiquinone oxidoreductase, 20 Kd subunit
73 NDUFS8interactor220.64529.887Fer4_7 (PF12838, IPR001450): 4Fe-4S dicluster domain
Fer4_16 (PF13484): 4Fe-4S double cluster binding domain
74 NDUFV1interactor320.50280.680Complex1_51K (PF01512, IPR011538): Respiratory-chain NADH dehydrogenase 51 Kd subunit
NADH_4Fe-4S (PF10589, IPR019575, SM00928): NADH-ubiquinone oxidoreductase-F iron-sulfur binding region
SLBB (PF10531, IPR019554): SLBB domain
75 NDUFV2interactor240.68819.4572Fe-2S_thioredx (PF01257, IPR002023): Thioredoxin-like [2Fe-2S] ferredoxin
76 NDUFV3interactor150.71425.873DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755)
IMUP (PF15761, IPR026621): Immortalisation up-regulated protein
NDUFV3 (PF15880, IPR026193): NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial
77 NR2C1interactor120.68213.539zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
DUF2318 (PF10080, IPR018758): Predicted membrane protein (DUF2318)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
78 NR2C2APinteractor100F5_F8_type_C (PF00754, IPR000421, SM00231): F5/8 type C domain
79 NUP188interactor2028.322Nup188 (PF10487, IPR018864): Nucleoporin subcomplex protein binding to Pom34
Nup192 (PF11894, IPR021827): Nuclear pore complex scaffold, nucleoporins 186/192/205
80 OGDHinteractor50.7001.556E1_dh (PF00676, IPR001017): Dehydrogenase E1 component
Transket_pyr (PF02779, IPR005475, SM00861): Transketolase, pyrimidine binding domain
2-oxogl_dehyd_N (PF16078, IPR032106): 2-oxoglutarate dehydrogenase N-terminus
OxoGdeHyase_C (PF16870, IPR031717): 2-oxoglutarate dehydrogenase C-terminal
81 PARK2suppressor220.233570.346IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
82 PATZ1oncoprotein40.6670.515AT_hook (PF02178, IPR017956, SM00384): AT hook motif
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
zf-C2H2_assoc3 (PF16637): Putative zinc-finger between two C2H2 zinc-fingers on Patz
83 PDLIM7interactor40.500103.134LIM (PF00412, IPR001781, SM00132): LIM domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein
DUF4749 (PF15936, IPR031847): Domain of unknown function (DUF4749)
84 PELI1interactor21.0000Pellino (PF04710, IPR006800): Pellino
85 PELI2interactor21.0000Pellino (PF04710, IPR006800): Pellino
86 PRPF40Aprotein found in more fusions50.33338.834FF (PF01846, IPR002713, SM00441): FF domain
MCR_alpha (PF02249, IPR009047): Methyl-coenzyme M reductase alpha subunit, C-terminal domain
Transformer (PF06495, IPR010519): Fruit fly transformer protein
WW (PF00397, IPR001202, SM00456): WW domain
YqzE (PF14038, IPR025622): YqzE-like protein
SPT6_acidic (PF14632, IPR028083): Acidic N-terminal SPT6
SRRM_C (PF15230, IPR029360): Serine/arginine repetitive matrix protein C-terminus
SOBP (PF15279, IPR026092): Sine oculis-binding protein
IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
87 PRPHinteractor100Filament (PF00038, IPR001664): Intermediate filament protein
Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region
TolA_bind_tri (PF16331, IPR032519): TolA binding protein trimerisation
88 PRRT2interactor30.6670.182CD225 (PF04505, IPR007593): Interferon-induced transmembrane protein
Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
89 RBBP4oncoprotein120.69715.295eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein
CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
90 RBCK1interactor90.500183.907GAGA (PF09237, IPR015318): GAGA factor
IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
91 RBMX2interactor30.33312.868DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19
92 RPL14interactor110.400365.950KOW (PF00467, IPR005824, SM00739): KOW motif
Ribosomal_L14e (PF01929, IPR002784): Ribosomal protein L14
UPF0688 (PF15772, IPR031530): UPF0688 family
93 RPL23interactor80.60746.971Ribosomal_L14 (PF00238, IPR000218): Ribosomal protein L14p/L23e
94 RPP38interactor100Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
95 RPS14interactor100.444145.827Ribosomal_S11 (PF00411, IPR001971): Ribosomal protein S11
96 RPS2interactor120.424135.184Ribosomal_S5 (PF00333, IPR013810): Ribosomal protein S5, N-terminal domain
Ribosomal_S5_C (PF03719, IPR005324): Ribosomal protein S5, C-terminal domain
97 RXRBinteractor100zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
Nuc_recep-AF1 (PF11825, IPR021780): Nuclear/hormone receptor activator site AF-1
98 S100A4interactor100S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
99 SDHBsuppressor140.60416.704Fer2_3 (PF13085, IPR025192): 2Fe-2S iron-sulfur cluster binding domain
Fer4_8 (PF13183, IPR017896): 4Fe-4S dicluster domain
Fer4_17 (PF13534): 4Fe-4S dicluster domain
100 SLC25A5interactor120.348191.236Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
101 SMARCC1suppressor100.55659.985SWIRM (PF04433, IPR007526): SWIRM domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
DUF2618 (PF10940, IPR021237): Protein of unknown function (DUF2618)
PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1
SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal
SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal
102 TAB1interactor40.8330.476PP2C (PF00481, IPR001932): Protein phosphatase 2C
103 TAB2oncoprotein120.45598.457CUE (PF02845, IPR003892, SM00546): CUE domain
DivIC (PF04977, IPR007060): Septum formation initiator
Mnd1 (PF03962, IPR005647): Mnd1 family
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
104 TANC2interactor100RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat
AAA_16 (PF13191): AAA ATPase domain
TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
105 TOMM20interactor60.46768.138RSN1_7TM (PF02714, IPR003864): Calcium-dependent channel, 7TM region, putative phosphate
MAS20 (PF02064, IPR002056): MAS20 protein import receptor
106 TRAF6protein found in more fusions130.242503.864SlyX (PF04102, IPR007236): SlyX
zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
107 TRIM28protein found in more fusions90.7863.171ASFV_J13L (PF05568, IPR008385): African swine fever virus J13L protein
K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
PHD (PF00628, IPR019787, SM00249): PHD-finger
FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2
108 UBE2G2interactor31.0000UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
109 UQCRBinteractor220.381153.582UCR_14kD (PF02271, IPR003197): Ubiquinol-cytochrome C reductase complex 14kD subunit
110 UQCRC2oncoprotein220.476211.477Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16)
Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain
111 UQCRHinteractor40.6670.422Herpes_pp85 (PF04637, IPR006731): Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25)
112 VAPAinteractor290.419155.930DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
UL45 (PF05473, IPR008646): UL45 protein, carbohydrate-binding C-type lectin-like
Motile_Sperm (PF00635, IPR000535): MSP (Major sperm protein) domain
113 VDAC1interactor210.476287.138Porin_3 (PF01459, IPR027246): Eukaryotic porin
114 VDAC2interactor210.52953.456Porin_3 (PF01459, IPR027246): Eukaryotic porin
115 VDAC3protein found in more fusions180.49038.084Porin_3 (PF01459, IPR027246): Eukaryotic porin

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