Find Fusion Network

Visualization interactions

Powered by Cytoscape Web for: parental proteins NDUFS4, NR2C2 (from a repository: Tue Jul 30 00:32:22 2019)

Examples AFF1 MLL ACTN4 + MLLAFF1 + MLLALK + MSNALK + TFGALK + TPM3ALK + TPM4ASXL2 + KAT6AATF1 + FUSBCR + ABL1BCR + FGFR1CCND1 + TACSTD2CD74 + ROS1CDK6 + MLLCOL1A1 + PDGFBCREB3L2 + PPARGCREB3L2 + FUSCREBBP + KAT6ADAZAP1 + MEF2DELL + MLLEPS15 + MLLERG + EWSR1ERG + FUSERG + TMPRSS2ETV5 + TMPRSS2ETV6 + ABL1ETV6 + NTRK3ETV6 + PAX5EWSR1 + FLI1EWSR1 + WT1FOXO1 + PAX3FOXP1 + PAX5FRYL + MLLGAS7 + MLLGMPS + MLLGOLGA5 + RETHOOK3 + RETHOXC13 + NUP98HOXD13 + NUP98MECOM + RUNX1MKL1 + RBM15MLL + MLLT1MLL + MLLT4MLL + MLLT10MLL + PICALMMLLT10 + PICALMNCOA1 + PAX3NIN + PDGFRBNPM1 + RARANRG1 + ODZ4NTRK1 + TFGNUMA1 + RARANUP98 + PHF23PAX5 + ZNF521PBX1 + TCF3RET + TRIM27ROS1 + SLC34A2PML + RARAPRKAR1A + RARAPRKAR1A + RETRUNX1 + RUNX1T1RUNX1 + SH3D19	Cytoscape Web will replace the contents your graph	PPI Properties: Click on nodes or edges
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Statistics and Network structure information

Statistic of PPI Value(s) The number of interactors (fusion and proteins) 115 The number (and %) of the onco-proteins 28 (24.35 %) The number (and %) of the tumor suppressors 9 (7.83 %) Total number of binary PPIs (saturation %) 757 (11.55 %) The number (and %) of affected PPIs 114 (15.06 %) The number of possible different fusions 22 PPI diameter 5 PPI radius 3 The average degree of PPI 12.591 Assortativity coefficient -0.1195 The network average Clustering coefficient 0.511 The number (and %) of a zero Clustering coefficients 13 (11.30 %) The number (and %) of a zero Betweenness Centrality 19 (16.52 %)

ACTIVE INTERACTORS

List of the fusions
PPI for parental proteins: NDUFS4,NR2C2	All fusions
Proteins found in more fusions	ITSN2 (see 5 fusions); TAB2 (see 1 fusions); TRAF6 (see 1 fusions); APP (see 5 fusions); ATP1A1/VDAC3 (see 2 fusions); HSP90AA1 (see 6 fusions); TRIM28 (see 1 fusions); DCAF1 (see 1 fusions); HDAC4 (see 1 fusions); PARK2 (see 1 fusions); CD2AP (see 1 fusions); NDUFS3 (see 2 fusions); HNF4A (see 1 fusions); ALDOA (see 2 fusions); KDM1A (see 3 fusions); SMARCC1 (see 2 fusions); EED/TRIM28 (see 1 fusions); ATP5A1 (see 1 fusions); DDB1 (see 4 fusions); PRPF40A (see 2 fusions); CHD4 (see 6 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	NDUFS4	parental protein	73	0.178	3887.384	ETC_C1_NDUFA4 (PF04800, IPR006885): ETC complex I subunit conserved region
2	NR2C2	parental protein	41	0.127	2745.544	Flagellin_N (PF00669, IPR001029): Bacterial flagellin N-terminal helical region zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
3	ABCD3	interactor	5	0.800	0.284	ABC_membrane_2 (PF06472, IPR010509): ABC transporter transmembrane region 2 ABC_tran (PF00005, IPR003439): ABC transporter
4	AFDN	oncoprotein	2	0	32.617	DIL (PF01843, IPR018444, SM01132): DIL domain DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) FHA (PF00498, IPR000253, SM00240): FHA domain MAP7 (PF05672, IPR008604): MAP7 (E-MAP-115) family MAS20 (PF02064, IPR002056): MAS20 protein import receptor Pap_E4 (PF02711, IPR003861): E4 protein PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain ARGLU (PF15346): Arginine and glutamate-rich 1
5	ALDOA	protein found in more fusions	6	0.300	81.977	Glycolytic (PF00274, IPR000741): Fructose-bisphosphate aldolase class-I
6	ALDOC	interactor	2	1.000	0	Glycolytic (PF00274, IPR000741): Fructose-bisphosphate aldolase class-I
7	APP	protein found in more fusions	22	0.233	768.486	APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP) BUD22 (PF09073, IPR015158): BUD22 IncA (PF04156, IPR007285): IncA protein Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
8	AR	oncoprotein	12	0.400	44.383	Androgen_recep (PF02166, IPR001103): Androgen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
9	ATAD3A	interactor	8	0.321	238.359	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) DUF3523 (PF12037, IPR021911): Domain of unknown function (DUF3523)
10	ATP1A1	protein found in more fusions	12	0.682	5.333	Cation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase Tetraspannin (PF00335, IPR018499): Tetraspanin family Cation_ATPase (PF13246): Cation transport ATPase (P-type)
11	ATP2A2	interactor	3	1.000	0	Cation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase HAD (PF12710): haloacid dehalogenase-like hydrolase Cation_ATPase (PF13246): Cation transport ATPase (P-type)
12	ATP5A1	protein found in more fusions	15	0.648	62.709	ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C (PF00306, IPR000793): ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain
13	ATP5C1	interactor	16	0.617	20.520	ATP-synt (PF00231, IPR000131): ATP synthase ACT_4 (PF13291, IPR002912): ACT domain
14	ATP5F1	interactor	20	0.447	225.231	Mt_ATP-synt_B (PF05405, IPR008688): Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF2105 (PF09878, IPR019212): Predicted membrane protein (DUF2105)
15	ATP5PO	interactor	18	0.569	31.594	OSCP (PF00213, IPR000711): ATP synthase delta (OSCP) subunit
16	ATP6V0D1	interactor	18	0.477	55.729	vATP-synt_AC39 (PF01992, IPR002843): ATP synthase (C/AC39) subunit
17	CACNA2D1	interactor	1	0	0	dCache_1 (PF02743, IPR004010): Cache domain VGCC_alpha2 (PF08473, IPR013680): Neuronal voltage-dependent calcium channel alpha 2acd VWA (PF00092, IPR002035, SM00327): von Willebrand factor type A domain VWA_N (PF08399, IPR013608): VWA N-terminal VWA_2 (PF13519, IPR002035): von Willebrand factor type A domain
18	CD2AP	protein found in more fusions	2	0	0	SH3_1 (PF00018, IPR001452, SM00326): SH3 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain betaPIX_CC (PF16523, IPR032409): betaPIX coiled coil
19	CHD4	oncoprotein	11	0.822	3.967	CDC27 (PF09507, IPR019038): DNA polymerase subunit Cdc27 CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain CHDNT (PF08073, IPR012958): CHDNT (NUC034) domain Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain DTHCT (PF08070, IPR012542): DTHCT (NUC029) region DUF1086 (PF06461, IPR009462, SM01146): Domain of Unknown Function (DUF1086) DUF1087 (PF06465, IPR009463, SM01147): Domain of Unknown Function (DUF1087) PHD (PF00628, IPR019787, SM00249): PHD-finger Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain FAM176 (PF14851): FAM176 family Coilin_N (PF15862, IPR031722): Coilin N-terminus
20	COX15	interactor	7	0.762	2.301	COX15-CtaA (PF02628, IPR003780): Cytochrome oxidase assembly protein Peptidase_S3 (PF00944, IPR000930): Alphavirus core protein
21	COX4I1	interactor	13	0.551	22.119	COX4 (PF02936, IPR004203): Cytochrome c oxidase subunit IV
22	COX6B1	interactor	10	0.694	6.169	COX6B (PF02297, IPR003213): Cytochrome oxidase c subunit VIb
23	COX7A2L	interactor	5	0.700	0.700	COX7a (PF02238, IPR003177): Cytochrome c oxidase subunit VII
24	CUL4B	oncoprotein	11	0.309	237.498	Cullin (PF00888, IPR001373, SM00182): Cullin family EBP50_C (PF09007, IPR015098): EBP50, C-terminal Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain PG_binding_4 (PF12229, IPR022029): Putative peptidoglycan binding domain MDFI (PF15316, IPR026134): MyoD family inhibitor
25	CYC1	interactor	20	0.363	100.287	Cytochrom_C1 (PF02167, IPR002326): Cytochrome C1 family
26	DCAF1	protein found in more fusions	7	0.600	21.527	DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) LisH (PF08513, IPR013720, SM00667): LisH ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
27	DDB1	protein found in more fusions	9	0.536	13.593	CPSF_A (PF03178, IPR004871): CPSF A subunit region MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term
28	DLAT	interactor	5	0.600	1.730	2-oxoacid_dh (PF00198, IPR001078): 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl (PF00364, IPR000089): Biotin-requiring enzyme E3_binding (PF02817, IPR004167): e3 binding domain Rib_recp_KP_reg (PF05104, IPR007794): Ribosome receptor lysine/proline rich region Stm1_N (PF09598, IPR019084): Stm1 NICE-1 (PF15845, IPR031698): Cysteine-rich C-terminal 1 family
29	DNAJC30	interactor	4	0.500	5.100	DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
30	DNMT1	suppressor	11	0.822	3.315	BAH (PF01426, IPR001025, SM00439): BAH domain DMAP_binding (PF06464, IPR010506, SM01137): DMAP1-binding Domain DNA_methylase (PF00145, IPR001525): C-5 cytosine-specific DNA methylase zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain DNMT1-RFD (PF12047, IPR022702): Cytosine specific DNA methyltransferase replication foci domain
31	EED	suppressor	20	0.263	462.318	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
32	ESR1	suppressor	21	0.247	524.178	Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
33	FOXL1	oncoprotein	1	0	0	Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
34	FUBP1	oncoprotein	6	0.333	121.739	DUF1897 (PF09005, IPR015096): Domain of unknown function (DUF1897) KH_1 (PF00013, IPR004088, SM00322): KH domain CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
35	FUBP3	interactor	5	0.500	85.923	DUF1897 (PF09005, IPR015096): Domain of unknown function (DUF1897) KH_1 (PF00013, IPR004088, SM00322): KH domain
36	GOLT1B	interactor	32	0.415	415.713	Got1 (PF04178, IPR007305): Got1/Sft2-like family
37	HDAC1	suppressor	17	0.483	53.182	FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
38	HDAC3	suppressor	14	0.449	47.572	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
39	HDAC4	oncoprotein	10	0.472	246.570	Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
40	HNF4A	suppressor	5	1.000	0	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
41	HSP90AA1	oncoprotein	14	0.295	472.630	HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein
42	ITSN2	protein found in more fusions	4	0.333	202.564	C2 (PF00168, IPR000008, SM00239): C2 domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH3_2 (PF07653, IPR011511): Variant SH3 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) SH3_9 (PF14604, IPR001452): Variant SH3 domain MRP-S26 (PF14943, IPR026140): Mitochondrial ribosome subunit S26 VIR_N (PF15912, IPR031801): Virilizer, N-terminal PH_13 (PF16652, IPR001849): Pleckstrin homology domain
43	JAZF1	oncoprotein	1	0	0	ARS2 (PF04959, IPR007042): Arsenite-resistance protein 2 zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain zf-C2H2_aberr (PF17017, IPR031514): Aberrant zinc-finger
44	KDM1A	protein found in more fusions	17	0.433	1175.412	Amino_oxidase (PF01593, IPR002937): Flavin containing amine oxidoreductase CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain SWIRM (PF04433, IPR007526): SWIRM domain DUF4298 (PF14131, IPR025384): Domain of unknown function (DUF4298)
45	KLHL7	interactor	2	0	0	BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif Kelch_6 (PF13964): Kelch motif
46	M6PR	interactor	2	1.000	0	Man-6-P_recep (PF02157, IPR028927): Mannose-6-phosphate receptor
47	MARC1	interactor	5	0.400	6.638	MOSC (PF03473, IPR005302): MOSC domain MOSC_N (PF03476, IPR005303): MOSC N-terminal beta barrel domain
48	MGST3	interactor	3	1.000	0	MAPEG (PF01124, IPR001129): MAPEG family
49	MRPL15	interactor	8	0.429	25.704	Ribosomal_L27A (PF00828, IPR021131): Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
50	MT-ND5	interactor	9	0.972	0.083	NADH5_C (PF06455, IPR010934): NADH dehydrogenase subunit 5 C-terminus Proton_antipo_M (PF00361, IPR001750): Proton-conducting membrane transporter Proton_antipo_N (PF00662, IPR001516): NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus
51	MTA1	oncoprotein	9	0.917	1.650	BAH (PF01426, IPR001025, SM00439): BAH domain ELM2 (PF01448, IPR000949): ELM2 domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain GATA (PF00320, IPR000679, SM00401): GATA zinc finger
52	ND1	interactor	8	0.964	0.083	NA
53	ND4	interactor	6	0.933	0.083	NA
54	NDUFA11	interactor	21	0.667	16.037	7kD_coat (PF02495, IPR003411): 7kD viral coat protein Tim17 (PF02466, IPR003397): Tim17/Tim22/Tim23/Pmp24 family
55	NDUFA12	interactor	35	0.455	146.785	NDUFA12 (PF05071, IPR007763): NADH ubiquinone oxidoreductase subunit NDUFA12
56	NDUFA13	interactor	14	0.868	3.224	GRIM-19 (PF06212, IPR009346): GRIM-19 protein
57	NDUFA2	interactor	17	0.647	29.252	L51_S25_CI-B8 (PF05047, IPR007741, SM00916): Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain
58	NDUFA4	interactor	33	0.433	188.831	B12D (PF06522, IPR010530): NADH-ubiquinone reductase complex 1 MLRQ subunit
59	NDUFA7	interactor	14	0.527	179.016	CI-B14_5a (PF07347, IPR009947): NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a)
60	NDUFA8	interactor	29	0.466	512.145	CHCH (PF06747, IPR010625): CHCH domain Pet191_N (PF10203, IPR018793): Cytochrome c oxidase assembly protein PET191 Cdd1 (PF11731, IPR021725): Pathogenicity locus
61	NDUFA9	interactor	33	0.502	102.269	Epimerase (PF01370, IPR001509): NAD dependent epimerase/dehydratase family
62	NDUFAF3	interactor	12	0.652	104.314	DUF498 (PF04430, IPR007523): Protein of unknown function (DUF498/DUF598)
63	NDUFB10	interactor	14	0.659	14.586	NDUFB10 (PF10249, IPR019377): NADH-ubiquinone oxidoreductase subunit 10
64	NDUFB4	interactor	17	0.581	55.006	NDUF_B4 (PF07225, IPR009866): NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4)
65	NDUFB5	interactor	12	0.833	2.531	NDUF_B5 (PF09781, IPR019173): NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit
66	NDUFB8	interactor	18	0.529	46.914	NDUF_B8 (PF05821, IPR008699): NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8)
67	NDUFS1	interactor	30	0.508	527.030	NADH_dhqG_C (PF09326, IPR015405): NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer4 (PF00037, IPR001450): 4Fe-4S binding domain Molybdopterin (PF00384, IPR006656): Molybdopterin oxidoreductase NADH-G_4Fe-4S_3 (PF10588, IPR019574, SM00929): NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2_4 (PF13510): 2Fe-2S iron-sulfur cluster binding domain
68	NDUFS2	interactor	23	0.577	125.300	Complex1_49kDa (PF00346, IPR001135): Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases (PF00374, IPR001501): Nickel-dependent hydrogenase
69	NDUFS3	protein found in more fusions	35	0.467	143.928	Complex1_30kDa (PF00329, IPR001268): Respiratory-chain NADH dehydrogenase, 30 Kd subunit
70	NDUFS5	interactor	28	0.537	67.557	Ndufs5 (PF10200, IPR019342): NADH:ubiquinone oxidoreductase, NDUFS5-15kDa
71	NDUFS6	interactor	23	0.672	31.665	Thiolase_C (PF02803, IPR020617): Thiolase, C-terminal domain zf-CHCC (PF10276, IPR019401, SM00400): Zinc-finger domain
72	NDUFS7	interactor	20	0.784	8.665	Oxidored_q6 (PF01058, IPR006137): NADH ubiquinone oxidoreductase, 20 Kd subunit
73	NDUFS8	interactor	22	0.645	29.887	Fer4_7 (PF12838, IPR001450): 4Fe-4S dicluster domain Fer4_16 (PF13484): 4Fe-4S double cluster binding domain
74	NDUFV1	interactor	32	0.502	80.680	Complex1_51K (PF01512, IPR011538): Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S (PF10589, IPR019575, SM00928): NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB (PF10531, IPR019554): SLBB domain
75	NDUFV2	interactor	24	0.688	19.457	2Fe-2S_thioredx (PF01257, IPR002023): Thioredoxin-like [2Fe-2S] ferredoxin
76	NDUFV3	interactor	15	0.714	25.873	DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755) IMUP (PF15761, IPR026621): Immortalisation up-regulated protein NDUFV3 (PF15880, IPR026193): NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial
77	NR2C1	interactor	12	0.682	13.539	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) DUF2318 (PF10080, IPR018758): Predicted membrane protein (DUF2318) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
78	NR2C2AP	interactor	1	0	0	F5_F8_type_C (PF00754, IPR000421, SM00231): F5/8 type C domain
79	NUP188	interactor	2	0	28.322	Nup188 (PF10487, IPR018864): Nucleoporin subcomplex protein binding to Pom34 Nup192 (PF11894, IPR021827): Nuclear pore complex scaffold, nucleoporins 186/192/205
80	OGDH	interactor	5	0.700	1.556	E1_dh (PF00676, IPR001017): Dehydrogenase E1 component Transket_pyr (PF02779, IPR005475, SM00861): Transketolase, pyrimidine binding domain 2-oxogl_dehyd_N (PF16078, IPR032106): 2-oxoglutarate dehydrogenase N-terminus OxoGdeHyase_C (PF16870, IPR031717): 2-oxoglutarate dehydrogenase C-terminal
81	PARK2	suppressor	22	0.233	570.346	IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
82	PATZ1	oncoprotein	4	0.667	0.515	AT_hook (PF02178, IPR017956, SM00384): AT hook motif BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger zf-C2H2_assoc3 (PF16637): Putative zinc-finger between two C2H2 zinc-fingers on Patz
83	PDLIM7	interactor	4	0.500	103.134	LIM (PF00412, IPR001781, SM00132): LIM domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein DUF4749 (PF15936, IPR031847): Domain of unknown function (DUF4749)
84	PELI1	interactor	2	1.000	0	Pellino (PF04710, IPR006800): Pellino
85	PELI2	interactor	2	1.000	0	Pellino (PF04710, IPR006800): Pellino
86	PRPF40A	protein found in more fusions	5	0.333	38.834	FF (PF01846, IPR002713, SM00441): FF domain MCR_alpha (PF02249, IPR009047): Methyl-coenzyme M reductase alpha subunit, C-terminal domain Transformer (PF06495, IPR010519): Fruit fly transformer protein WW (PF00397, IPR001202, SM00456): WW domain YqzE (PF14038, IPR025622): YqzE-like protein SPT6_acidic (PF14632, IPR028083): Acidic N-terminal SPT6 SRRM_C (PF15230, IPR029360): Serine/arginine repetitive matrix protein C-terminus SOBP (PF15279, IPR026092): Sine oculis-binding protein IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
87	PRPH	interactor	1	0	0	Filament (PF00038, IPR001664): Intermediate filament protein Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region TolA_bind_tri (PF16331, IPR032519): TolA binding protein trimerisation
88	PRRT2	interactor	3	0.667	0.182	CD225 (PF04505, IPR007593): Interferon-induced transmembrane protein Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
89	RBBP4	oncoprotein	12	0.697	15.295	eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
90	RBCK1	interactor	9	0.500	183.907	GAGA (PF09237, IPR015318): GAGA factor IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
91	RBMX2	interactor	3	0.333	12.868	DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19
92	RPL14	interactor	11	0.400	365.950	KOW (PF00467, IPR005824, SM00739): KOW motif Ribosomal_L14e (PF01929, IPR002784): Ribosomal protein L14 UPF0688 (PF15772, IPR031530): UPF0688 family
93	RPL23	interactor	8	0.607	46.971	Ribosomal_L14 (PF00238, IPR000218): Ribosomal protein L14p/L23e
94	RPP38	interactor	1	0	0	Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
95	RPS14	interactor	10	0.444	145.827	Ribosomal_S11 (PF00411, IPR001971): Ribosomal protein S11
96	RPS2	interactor	12	0.424	135.184	Ribosomal_S5 (PF00333, IPR013810): Ribosomal protein S5, N-terminal domain Ribosomal_S5_C (PF03719, IPR005324): Ribosomal protein S5, C-terminal domain
97	RXRB	interactor	1	0	0	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor Nuc_recep-AF1 (PF11825, IPR021780): Nuclear/hormone receptor activator site AF-1
98	S100A4	interactor	1	0	0	S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
99	SDHB	suppressor	14	0.604	16.704	Fer2_3 (PF13085, IPR025192): 2Fe-2S iron-sulfur cluster binding domain Fer4_8 (PF13183, IPR017896): 4Fe-4S dicluster domain Fer4_17 (PF13534): 4Fe-4S dicluster domain
100	SLC25A5	interactor	12	0.348	191.236	Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
101	SMARCC1	suppressor	10	0.556	59.985	SWIRM (PF04433, IPR007526): SWIRM domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain DUF2618 (PF10940, IPR021237): Protein of unknown function (DUF2618) PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1 SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal
102	TAB1	interactor	4	0.833	0.476	PP2C (PF00481, IPR001932): Protein phosphatase 2C
103	TAB2	oncoprotein	12	0.455	98.457	CUE (PF02845, IPR003892, SM00546): CUE domain DivIC (PF04977, IPR007060): Septum formation initiator Mnd1 (PF03962, IPR005647): Mnd1 family zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
104	TANC2	interactor	1	0	0	RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat AAA_16 (PF13191): AAA ATPase domain TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat
105	TOMM20	interactor	6	0.467	68.138	RSN1_7TM (PF02714, IPR003864): Calcium-dependent channel, 7TM region, putative phosphate MAS20 (PF02064, IPR002056): MAS20 protein import receptor
106	TRAF6	protein found in more fusions	13	0.242	503.864	SlyX (PF04102, IPR007236): SlyX zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
107	TRIM28	protein found in more fusions	9	0.786	3.171	ASFV_J13L (PF05568, IPR008385): African swine fever virus J13L protein K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PHD (PF00628, IPR019787, SM00249): PHD-finger FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2
108	UBE2G2	interactor	3	1.000	0	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
109	UQCRB	interactor	22	0.381	153.582	UCR_14kD (PF02271, IPR003197): Ubiquinol-cytochrome C reductase complex 14kD subunit
110	UQCRC2	oncoprotein	22	0.476	211.477	Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16) Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain
111	UQCRH	interactor	4	0.667	0.422	Herpes_pp85 (PF04637, IPR006731): Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25)
112	VAPA	interactor	29	0.419	155.930	DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) UL45 (PF05473, IPR008646): UL45 protein, carbohydrate-binding C-type lectin-like Motile_Sperm (PF00635, IPR000535): MSP (Major sperm protein) domain
113	VDAC1	interactor	21	0.476	287.138	Porin_3 (PF01459, IPR027246): Eukaryotic porin
114	VDAC2	interactor	21	0.529	53.456	Porin_3 (PF01459, IPR027246): Eukaryotic porin
115	VDAC3	protein found in more fusions	18	0.490	38.084	Porin_3 (PF01459, IPR027246): Eukaryotic porin

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